>Homo_sapiens_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------MTRWVPTKR ------------EEKYGVAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KGHSATG---KSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPG------------------VNE QLYKAMKALES--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSINDMMSSMSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------M GLLTIQKLYCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSHILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMVQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCVAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTDRYLQ--EHPEAHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGV RIMPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDL-----EKE-KKDKKKEKRNS KHQEIFEKEFKPTDISLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVMNVIGSE--- ------------RRFSVSPSSPSS-----QQTPPP-VTPRA--------------KLSFSMQSS---------------- ------------LELNGMTG---ADVADVPPPLPLKGSVADYGNLMENQDL-------LGSPTPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQASVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Pan_troglodytes_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------FYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KGHSATG---KSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPG------------------VNE QLYKAMKALES--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSINDMMSSMSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------M GLLTIQKLYCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSHILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMVQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCVAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGQKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFTNYEKA------ -----FFTDRYLQ--EHPEAHEKIEKLKDLIAWQ---------------------------------------------- ---PSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDL-----EKE-KKDKKKEKRNS KHQEIFEKEFKPTDISLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVMNVIGSE--- ------------RRFSVSPSSPSS-----QQTPPP-VTPRA--------------KLSFSMQSS---------------- ------------LELNGMTG---ADVADVPPPLPLKGSVADYGNLMENQDL-------LGSPTPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- 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-------------------------------------------------------------------------------- ----------------------------------- >Macaca_mulatta_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------AFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KGHSATG---KSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPG------------------VNE QLYKAMKALES--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSINDMMSSMSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------M GLLTIQKLYCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSHILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMVQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--VREEVDTTFLAFITLES---VNLKN-FWSLLRAFVFSLYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCVAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFTNYEKARDPPAC SGQAAFFTDRYLQ--EHPEAHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGV RIMPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDL-----EKE-KKDKKKEKRNS KHQEIFEKEFKPTDISVQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINVIGSE--- ------------RRFSVSPSSPSC-----QQTPPP-VTPRA--------------KLSFSMQSS---------------- ------------LELNGMTG---ADVADVPPPLPLKGSVADYGNLMENQDL-------LGSPTPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Callithrix_jacchus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------AFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KGHSATG---KSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDNAEKPG------------------VNE QLYKAMKALES--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSINDMVSSMSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------V GLLTIQKLYCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSHILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMVQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKEQLYQEIIHFFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGEDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFTNYEKA------ -----FFTDRYLQ--EHPEAREKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RILPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDL-----EKE-RKDKKKEKRNS KHQEIFEKEFKPTDISLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINIIGSE--- ------------RRFSVSPSSPSS-----QHTPPP-VTPRA--------------KLSFSVQSN---------------- ------------LELNGMMG---VDVADVPPPLPLKGSVADYGNVMENQDL-------LGSPTPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Mus_musculus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------MTRWVPTKR ------------EEKYGVAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEVASKQ-----VEE RLQEEK---SQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPM--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDSNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQA---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETLK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKGELEE-------KGHSATG---KGMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTNLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRTYVASAEKPG------------------VNE QLYKAIKALEY--------------IFKFIVRSR-----VLFNQLYENKGEAD-FVESLLQLFRSINDMMSSLSEL---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------A GLLTVQKLSCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -ELEACCQLLSNILEVLYR---------KDVGPTQRHVQIIMETLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNTMQN----KVFLRAINQYADMLNKRFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKDNRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-FQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYETEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPSFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKTSPGQ-YIQ--CFTVKPKLDL--PPRF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKISSMVQQHLD-DPGLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTDRYLQ--EHPEAHGQIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSGLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSFSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDP-----DKE-KKDKKKEKRNS KHQEIFDKEFKPADSSLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINVIGNE--- ------------RRFSVSPASPSS-----QQTPPP-VTPRA--------------KLSFSIQPS---------------- ------------LELNGMMG---MDVADVPPPLPLKGNMADYGNLMENQDM-------MVSPTSPPPPPPQRQQPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Rattus_norvegicus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------MTRWVPTKR ------------EEKYGVAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEVASKQ-----VEE RLQEEK---SQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDSNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETLK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKGELEE-------KGHSATG---KGMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTNLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRTYVASAEKPG------------------INE QLYKAIKALEY--------------IFKFIVRSR-----VLFNQLYENKGEAD-FVESLLQLFRSINDMMSSMSEL---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------V GLLTVQKLYCLIEIVHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSNILEVLYR---------KDVGPTQRHVQIIMEELLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDFHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNTMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKDNRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDACAAHLIQRDG-FQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYETELFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPSFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKTSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKISSMIQQHLD-DPGLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTDRYLQ--EHPEAHGQIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSGLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSFSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDP-----DKE-KKDKKKEKRNS KHQEIFDKEFKPADSSLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINVIGSE--- ------------RRFSVSPASPCS-----QPTPPP-VTPRA--------------KLSFSIQPN---------------- ------------LELNGMMG---MDVADVPPPLPLKGNMADYGNLMENQDL-------MGSPTSPPPPP-QRQQPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Oryctolagus_cuniculus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------MTRWVPTKR ------------EEKYGVAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRRKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEVASKQ-----VEE RLQEEK---SQKQNLDITRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDV HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KGHAVTG---KSLQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYVDNAEKPG------------------IND QLYKAMKALEY--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSINDMMSSLSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------V GLLTFRKLCCLIEIVHTDLFT---QHDCREILLPMMTDQLKRHLE---RQE----------------------------- -DLEACCQLLSDILEVLYR---------EDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRRATIPIFFDMMQCEFHSTR------------------SFQVFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKSGEVFVRLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYETEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-HIQ--CFTVKPKLDL--PLKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHAEAHEQIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSSLD--ERRGSRPRSMVRSFTMPSTSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDG-----DKE-RKDKKKEKRNS RHQETLEKDFRPADACPPQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVLSVVGSE--- ------------RRFSVSPSSSPA-----QQTPPP-VTPRA--------------KLSFSLQSS---------------- ------------VELNGMTT---VDLADVPPPLPLKGSMADYGNLMENQDS-------VGSATPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- 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----------------------------------- >Canis_familiaris_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------MRRPTPSAPHYKEREK ------------CLPGWSAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKRDKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KAHSATG---RSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYVDNAEKPG------------------INE QLYKAMKALEY--------------IFKFIVRSR-----ILFNQLYEDKGEAD-FMESLLQLFRSISDMMSSVSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTDFILNVP------M GLLTIQKLYCLIEIIHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSNILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHRECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKMNSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHPEAHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSSLD--DRRGNRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDP-----EKE-KKDKKKEKRNS KHQEIFDKEFKPTDISLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINVTGSE--- ------------RRFSVSPSPPSS-----QPTPPP-VTPRA--------------KLSFSLQSS---------------- ------------LELNGMTGMTGMDTAEVPPPLPLKGSMADYGNLMENQDL-------ISSPTPPPPPPHQRVSQP---- --------------ETRNTGF----------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Felis_catus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------TDWMRFNMKNK ------------QEQGR-AFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFASTPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-VNYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKRDKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEGISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAATYLS---LPSTKAELEE-------KAHSATG---RSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTSLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYVDNAEKPG------------------IND QLYKAMKALEY--------------IFKFIVRSR-----ILFNQLYEDKGEAD-FMESLLQLFRSISDMMRGESDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTDFILNVP------M GLLTIQKLYCLIEIIHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCHLLSNILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LTGNFVACMTAILRQMENYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKMNSMVQQHLH-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHPEAHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFSLEPLLPKKMHSRSQDK---LDKDDP-----DKE-KKDKKKEKRNS KHQELFDKEFKPTDVSLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINVTGSE--- ------------RRFSVSPSPPSS-----QPTPPP-VTPRA--------------KLSFSLQSS---------------- ------------LELNGMTGLTGMDTAEVPPPLPLKGSMADYGNLMENQDL-------ISSPTPPPPPPHQRHAPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Bos_taurus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------SVHMSLTHR ------------QEKHRTAFYNYDARGADELSLQIGDAVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPGDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEVASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DAGTYLS---LPSTKAELEE-------KGHSATG---KSMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTNLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYVDNAEKPG------------------ISD QLYKAMKALEY--------------IFKFIVRSR-----ILFNQLYENKGEAD-FVESLLQLFRSISDMMSSVSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTDFILNVP------V GLLTIQKLYCLIEIIHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSNILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKERLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKINSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHPEAHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFRQLKEKVEKQYGV RTMPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDP-----DKE-KKDKKKEKRNS KHQEIFDKEFKPTDIPLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINAMGGE--- ------------RRFSVSPSSPSS-----QSTPPP-VMPRA--------------KLSFSLQSS---------------- ------------LELNGMTVA-GLDVAEVPPPLPLKGTSTDYGTLNENLDL-------TGSPTPPPPPPHQRHLPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Loxodonta_africana_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------MTRWVPTKR ------------EEKYGVAFYNYDARGADELSLQIGDTVHILETYEG-WYRGYTLRKKSKKG--IFPASYIHLKEAIVEG KG--------QHETVIPSDLPLIQEVTTTLR-EWSTIWRQLYVQD-NREMFRSVRHMIYDLIEWRSQILSGTLPQDELKE LKKKITAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSFALFVNLKNVVCKIGEDAEVLMSLYDPV--ESKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKRDKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RKLTSGLRRPFGVAVMD------VTDIINGKLD-DEDKQ HFIPFQP---------------------VAGENDFLQTVINKVIAAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKTGFPEIIMP-GDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLE--HVIFPG AGDEAISEYKS-VIYYQVKQPRWFETVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DASTYLS---LPSTKAELEE-------KGHSATG---KGMQSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTNLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYVDNAEKPG------------------INE QLYKAMKALEY--------------IFKFIVRSR-----ILFNQLYEDKGEAD-FMESLLQLFRSINDMMSSLSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------L GLLTIQKLYCLIEIIHSDLFT---QHDCREILLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSNILEVLYR---------KDVGPTQRHVQLIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPSDWVIMNMMQN----KVFLRAISQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKELLYQEIIHYXXXXX-MWEEAIALGKELAEQYENEMFDYEQLSQLLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGLPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQ-YIQ--CFTVKPKLDL--PPKF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTIYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKIHSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHPESHEKIEKLKDLIAWQ---IPFLAEGIRIHGEKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSSLD--DRRGSRPRSMVRSFTMPSSSRPLS----------------VASVSSLSSDST--PSRPGSD--------- --------------------------------GFVLEPLLPKKMHSRSQDK---LDKDDA-----DKE-KKDKKKEKRNS RHQETFDKEFKPADVSSQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINPIGGE--- ------------RRFSVSPSPPTS-----QQAPPP-VTPRA--------------KLSFSLQSS---------------- ------------LELNGMTG---VEVANVPPPLPLKGSTADYGNVMENQDL-------VGSP--PPPPPHQRHQPPPLPS KTPPPPPPKTTRKQTSVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Dasypus_novemcinctus_DOCK1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MFRSVCHMIYDLIEWRSQILSGTLPQDELKE LKKKVTAKIDYGNR---------------------ILDLDLVVRDEDGN-ILDPELTSTISLFRAHEIASKQ-----VEE RLQEEK---SQKQNIDINRQAKFAATPSFALFVNLKNVVCKIGEDAEVLMSLYDPV--EFKFIS-ENYLVRWSSSGLPKD IDRLHNLRAVFTDLGSKDLKREKISFVCQIVR--------------------VGRMELRDNNT----------------- -----------------------------------------RRLTSGLRRPFGVAVMD------VTDIINGKVD-DEDKQ HFIPFQP---------------------VAGESDFLQTVINKVITAK-EVNHKGQG------------LWVTLKLLPGDI HQIRKEFPHLVDRTTAVARKMGFPEIIMP-GDVRNDIYITLVQGDFDKGSKTTAKNVEVTMSVYDEDGKRLE--RVIFPG AGDEAISEYKS-VIYYQVKQPRWFEIVK--VAIPIEDVNR--SHLRFTFRHRSSQDSKDKSE--KIFAL----AFVKLMR YDGTTLRDGEHDLIVYKA----EAKKLE--DASTYLS---LPSTKAELEE-------KGHAATG---RSMHSLGSCTISK DSFQISTLVCSTKLTQN-VDLLG-LLKWRSNTNLLQQN---LRQLMKVDGGEVVKFL--QDTLDALFNIMME-NSESETF DTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRNYMDNAEKPG------------------INE QLYKAMKALEY--------------IFKFIVRSR-----VLFNQLYEDKGEAD-FVESLLQLFRSINDMMSSLSDQ---- TVRVKG------------------------------AALKYLPTIVN-DVKLVFDPKELS--KMFTEFILNVP------M GLLTIQKLHCLIEIIHSDLFT---QHDCRELLLPMMTDQLKYHLE---RQE----------------------------- -DLEACCQLLSNILEVLYR---------KDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSE------------------- ----------------------------------------------------LIGNFVACMTAILRQMEDYHYAHLIKTF GKMRTD------------VVDFLMETFI-MFKNLIGK--NVYPFDWVIMNMMQN----KVFLRAINQYADMLNKKFLDQA N----FELQ--LWNNYFHLAVAFLTQES---LQLEN-FSSAKRAKILNKYGDMRRQIGFEIR-DMWYNLG--QHKIKFIP EMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR------------------SFQMFENEIITKLDHEVE-GGRGDE QYKVLFDKILLEHCR-------------------KHKYLAKTGETFVKLVVR--LMERLLDYR-----TIMHDENKENRM SCTVNVLN-----FYKEIER--EEMYIRYLYKLCDLHKECDNYT---EAAYTLLLHAKLLKWSEDVCAAHLTQRDG-YQA TTQGQLKEQLYQEIIHYFDKGK-MWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVK-VIRPKPDYFAVGYY GQGFPTFLRGKVFIYRG--KEYERREDFEARLLTQFPNAEKMKTTSPPGDDVKTSPGQ-YIQ--CFTVKPKLDL--PPRF H-RPVSEQIVS-FYRVNEVQRFEYSRP------IRKGEKNPD----------NEFAN--MWIERTMYTTAYKLPGILRWF EVKSVF------MVEISPLENAIETMQLTNDKIDSMVQQHLD-DPSLPINPLSMLLNGIVDPAVMGGFANYEKA------ -----FFTERYLQ--EHPEGHEKIEKLKDLIAWQ---IPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGV RTMPSGLD--SRRGSRPRSMVRSFTMPSSSRPLS----------------AASVSSLSSDST--PSRPGSD--------- --------------------------------GFALEPLLPKKMHSRSQDK---LDKDDL-----DKE-KKDKKKEKRNS KHQEIFDKEFKPTDVSLQQSEAVILSET---------------------------------------------------- -------------ISPLRPQRPKS--------------------------------------------QVINIMGSE--- ------------RRFSGSPSPPSS-----QQTPPP-VTPRC--------------KLSFSLQSS---------------- ------------LELNGMTS---MEGATVPPPLPLKGSMADYGNLMESQDL-------TGSPTSPPPPSHQRHLPPPLPS KTPPPPPPKTTRKQASVDSGIVQ--------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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