>Homo_sapiens_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------MEVRKLSISW QFLIVLVLI---------------LQILSAL-DFDPYRVLGVSRTASQADIKKAYK---------------KLAREWHPD KNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQ--REYRFRHFHENFYFDESFFHFPFN------ ----SERRDSIDEKYLLHFS--HYVNEVVPDSFKKPYLIKITSDWCFSCIHIEP----------------VWKEVIQELE ELGVGIGVVHAGYERRLAHH--LGAHSTPSI---------LGIINGKISFFHN----AVVRENLRQFVESLLPGNLVEKV -------TNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVG--------------------- ------------LRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDDFITRNKYLLAARLTSQKLFHEL CPVKRSHR-QRKYCVVLLT-----AETTKLSKPFE-AFLSFALANT-------QDTVRFVHVYSNRQQEFADTLLPDSEA FQGKSAV-----------------SILERRNTAGRVVYKTLEDPWIGSES-------------DKFILLGYLDQLRKDPA LLSSEAVLPDLTDELAPVFLLR-WFYSASDYISDCWDSIFHNNWREMMPLLSLIFSALFI-----LFG---TVIVQAFS- ----------------------DSNDERESSPPEKEEAQEKTGKTEPSFTKENS-SKIPKKGFVEVTELTDVTYTSNLVR LRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFS-FLSLDKHREWLEYLLEFAQ--------DAAPIPNQYD-- KHFMERDYTGYVLALNGHKKYFCLFKPQKTVEEEE-AIGSCSDVDSSLYLGE-----------------SRGKPSCGLGS RPIKGKLSKLSLWMERLLEGSLQRFYIPSWPELD---------------------------------------------- --------------------------------------------------------------------- >Mus_musculus_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------MELKRLGVSW RFLMVLVLI---------------LQSLSAL-DFDPYRVLGVSRTASQADIKKAYK---------------KLAREWHPD KNKDPGAEDRFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQKQQRE----HRFRHFHENFYFDESFFHFPFN------ ----AERRDSGDEKYLLHFS--HYVNEVLPESFKRPYLIKITSDWCFSCIHIEP----------------VWKEVVQELE GLGVGIGVVHAGYERRLAHH--LGAHSTPSI---------LGVISGKITFFHN----AVVHENLRQFVESLLPGNLVEKV -------TNKNYVRFLSGWQQENKPHALLFGQTPAVPLMYKLTAFAYKDYVSFGYVYVG--------------------- ------------LRGVEEMTRQYNVNLYTPTMLIFKEHINKPADVIQARGLKKQVIEDFIAQNKYLLASRLTSQRLFHEL CPVKRSHR-QRKYCVVLLT-----AETNKVSKPFE-AFLSFALANT-------QDTVRFVHVYSNRQQEFASTLLPDMEA FQGKSGV-----------------SILERRNTAGRVVFKTLEDPWTGSES-------------DKFVLLGYLDQLRKDPA FLSSEAVLPDLTDELAPVFFLR-WLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFI-----LFG---TVMVQAFS- ----------------------DSNEERESHPADKEEVPEKAGKTEPSFTKESS-SKIPKKGFVEVTELTDVTYTSNLVR LRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFS-FLTLDKHREWLEYLLEFAQ--------DAAPIPNQYD-- KHFMERDYTGYVLALNGHKKYFCLFKPLKTVDEET--VASC-DPDS-----------------------SRGKPSCGLGP KPLKGKLSKLSLWMERLLEGSLQRFYIPSWPELD---------------------------------------------- --------------------------------------------------------------------- >Canis_familiaris_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------MEVKKLSISW QFLIVLVLI---------------LQILSAL-DFDPYRVLGVSRTASQADIKKAYK---------------KLAREWHPD KNKDPGAEDKFIQISKAYEILSNEEKRSNYDHYGDAGENQGYQKQQQQ--REYRFRHFHENFYFDESFFHFPFN------ ----SERRGSIDEKYLLHFS--HYVNEVVPDSFKKPYLIKITSDWCFSCIHIEP----------------VWKEVVQELE RLGVGIGVVHAGYERRLAHH--LGAHSTPSI---------LGIINGKISFFHN----AVVRENLRQFVESLLPGNLVEKV -------TNKNYIRFLSGWQQENKPHVLLFDQMPVVPLLYKLTAFAYKDYLTFGYVRTG--------------------- ------------LREAEEMKRQYNVNVYAPTILIFKEHINKPADAIQARGMKKQVIDDFITQNKYLLAARLTSQRLFHEL CPVKRSHR-QRKYCVVLLT-----AEAAKLSKPFD-AFLSFALANT-------KDTVRFVHVYSNRQQEFANTLVPDSDT FQGKSAV-----------------SILERRTTGGRVVYKTLEAPWTGSES-------------DKLTLLGYLDQLRRDPA LLSSEAVLPDLTDELAPIFLLR-WFYSASDYISDCWDSIFHNNWREMMPLLSLVFSALFI-----LFG---TVIVQAFS- ----------------------DSNDERESNPPDKEEAHEKAGKTEPSFAKENS-SRIPKKGFVEVTELTDVTYTSNLVR LRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFS-FLSLDKHREWLEYLLEFAQ--------DAAPIPNQYD-- KHFMERDYTGYVLALNGHKKYFCLFKPQKAVEEEE-ALGSCSDLDSSLHLGD-----------------SRGKSSCGLGP RPIKGKLSKLSLWMERLLEGSLQRFYIPSWPELD---------------------------------------------- --------------------------------------------------------------------- >Gallus_gallus_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------MELGRAGP-A GLLLLLLLL---------------LAAQAAP-ERDPYRVLGVGRSSSQADIKKAYK---------------RLARQWHPD KNKDPGAEDKFIQISKAYEILSNEEKRANFDRYGDAGESQGYSQHQQ-----RQFHHFHEGFYFDESFFHFPFN------ ----SERRDTSDEKYLLHFS--HYINEIVPDSFKKPYLIKITSDWCFSCIHIEP----------------VWKEVAQELE ALGVGIGVVHAGYERRLAHH--LGAHSTPSI---------LGLINGKITFFHS----AVVRENLRQFVENLLPGNLVEKI -------TDKNYIRFLSNWKKENKPHVLLFDHMPVVPLLYKLTAFAYRDYLSFGYVYVG--------------------- ------------LRGTEELSSRYNINVYTPTLMIFKEHIDKPADVAQARDMKKQLIDDFLSQNKFLMAARLTNQRLFQEL CPVKKSHR-QRKHCVVLLT-----GEGDKFADAYE-AFLTFAVANT-------KDTLRFAHIYNDRQPEFADALLMDEEK YRGKSAV-----------------VILERRNNAGKIAYKTLEEAWQGSNE-------------DNFILLDLLDQLRTDPG LLSSETVLADLNDELAPMFLIR-WFYSTLDYILDCWDSLFHSNWREMMPLLSLLFSALFI-----LFG---TVIVQAFS- ----------------------DSSDTRDSPASEKKDTTAKTEKNDTSFNKESN-SRVPKKGFVEVTELTDINYNSNLVR LRPGHMNVVLILSNSTKTALLQKFALEVYTFTGSSSLHFS-FLSLDKHREWLEYLLEFAQ--------DAAPIPNQYD-- KHFLERDYTGYVLALNGHKKYFCLFKPHRSGDEGG-TLGACEDYDSSLHT-E-----------------ARGKSSCSPGS RSLKNKLHKLSFWMERLLEGSLQRFYIPSWPALD---------------------------------------------- --------------------------------------------------------------------- >Danio_rerio_DNAJC16_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------AAEHTVTMRTVVGLLSV IMLYVLLND---------------ATVESTA-EFDPYKVLGVTRSASQAEIKKVYK---------------RLAKEWHPD KNKNPEAEDMFIKITKSYEILTNEEKRASYDRYGQTDDTQPYGHR-HHG-----FRHFHDNFYFDESFFHFPFN------ ---NKGGRDFADSKYTLHFN--QYVNEVVPDSFKRPYLIKITSDWCFSCIHIEP----------------VWKETVQELE TTGIGIGVVDVGYERRLANH--LGAHQTPSI---------LGVVNGKVSFFHY----AVVKEHLIQFVDDLLPQRLIEKV -------TDKNNHEFLKSWHELNKPHVLLFDQVPSVPLLYKLTAFAFKDYVQFGYVDQG--------------------- ------------LSETAELLRKFNINTYAPTMLVFKEDVEKPADIIQAKGMKKQIIDEFISNNKFLLAPRLVNQKLFDEL CPVKQFHR-RRKYCILLIT-----GEDESYIPGNE-AFLLLASANA-------NDVLRFAYVYHRRQQPLCDILLKDKDD -TAPQQV-----------------VILERRNGAGKILYKPLLGGWNGSKE-------------DKHKLLEELQRLQKDPS ILNYNAILPELNNEFASMFLVR-WIYTAYDYLSEIIDDLLHNNWREMMPLLSLIFSALFI-----LFG---TVVIQAFSF S---------------------DSSEEKQPKMKVKE-TKSENGSPNTSNAS--S-SRPPKKNFVEVTELTDITYTSNLVK LRPGHINVVLVLTDGTKNILLSKFAKEVYSFTGSLTLHFS-FLNVDKHKEWMAAVLEFAQ--------DAMQIDTDED-E MGTRKVDYTGYVLALNGHKKYLCLFKPVYTGEDLDGK--AEEEGGVSRSRKS--------------------TTRSRSTS LQIHHKLDRLGLWMERLMEGTLPRYYVPAWPGLD---------------------------------------------- --------------------------------------------------------------------- >Danio_rerio_DNAJC16_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MYQKMGGWSVFVSCCAW AILLLALFG---------------DSLASAP-EFDPYSVLGVSKHASLTEIKKMYK---------------KLAREWHPD KNKSPGAEDMFIKITKSYEILSNEERRANYDRFGQMDENQNFARP-PQG-----FRQYHDSFYFDESFFHFPR------- -----TSRDFTESKHLLHYN--QYMNEVLPDSFKRPYLIKITSEWCFTCIHIEP----------------IWKDTVLELE PLGVGIGVVDIGYERQLANH--LGAHRTPSI---------LGLVNGKVTFFHY----SVVREHLRQFVESLLPQRLVEKV -------TDSNYLEFLNSWHEENKPRVIMFDIASNVPLLYKLTAFAYKDYVRFGYVDMG--------------------- ------------LTETSKVVQRFNINTYAPTMLLFKENTEKPADVIQARGMKKQILDEFVSNNRFLLVPRLVNQKLFDEL CPVKQFHR-RRKYCVLLVT-----GEGEQFVSVNE-AFFDFASSNT-------KEVLRFAYVDQRQQQPLCDTLLK--KD DTTPPQV-----------------IILERRSTSGRVLYRTVTGGWNGSDD-------------DKHRLHEQLELLQRDPS YLTHDAMLPELNNEFASMFLIQ-WINTAYDYLAQFYFDLLYSNWREMMPVLSLIFSALFI-----LFG---TVIIQAFS- --------------------DSGEEKPTKQKATESP--KTPESSPGPESTSS----RPPKKNFVEVTELTDITYMSNLVR LKPGHINVVLILTDASKQVLLRKFAKEVYSFSGSQNLHYS-FLNVDKHRQWMDSLMESAP--------DARSDEEEEVED PSTNKLDHTGHVLALNGHKKYFCVFRPVFTGEEAERSRYSDDDAATGGTSRT---------------SRSRSSSRQKATT LEIHHKLDRLGLWMERLMEGTLPRHYVSAWPGMDTITPQK---------------------------------------- --------------------------------------------------------------------- >Takifugu_rubripes_DNAJC16_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------SNMSWLLAV AVLLSMLLM---------------GDTHAVP-EMDPYKILGVTRAASQAEIKKVYK---------------RLAKEWHPD KNKHPGAEEMFIKITKSYEILSNEDKRNNYDRYGQTEDTQPYGSS-HYG-----HR--HDAFYFEESFFNFPYG------ ---SKNQRDFADSKYILHFN--QYVNDVVPNSYRRPYLIKITSDWCFSCIHIEP----------------VWKEVVQEME SLGVGIGVVDVGYERRLANH--LGAHRTPSI---------LGIVNGRVTFFHY----AVAKEHLRQFVEDLLPLRLVEQI -------TDANYQQLLNSWHELNKPHVFLFDQVPGVPLLYKLTAFAYRDYLQFGYVDQG--------------------- ------------LSETTNLQKKFNINSYAPTMLVFKENAQKPADIIQAKGMKKQIIDEFMANNKFLLVPRLVNQKLFDEL CPVKQFHR-RRKYCVLLLT-----GDEEPFASGNQ-EFFSFASTNT-------KEVVRFAYVYKRLQQPLCDILMQKQDN GQSPTQV-----------------VILERRNAAGKAFFKPVTA-WNGSEE-------------DKQRLLDELEQLKKDPS ILTHDAMLPELNNEFASVFLIR-WIYAFSDYLSEVIDDILHNNWREMMPLLSLIFSALFI-----LFG---TVVIQAFS- ----------------------DSSEDNQTKTKAKDGTRAENGSPRAGGAPRQE-SRAPKKNFVEVTELTDITYTSNLVK LRPGQMNVVLLLTDTSKNVLLSKFAKEVYSFTGSLTLHFS-FLNIDKHSQWMVALLDSSQ--------DAAQIAADDI-D GGNHKTDYTGYVLALNGHKKYFCLFKPVYTGEDLDSK--TSEEERMASGVRS------------------------NISI LQIHHKLDRLGLWMERLLEGTLPRYYITAWPEVD---------------------------------------------- --------------------------------------------------------------------- >Gasterosteus_aculeatus_DNAJC16_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------VAV VLVLSVLLA---------------GASHAGP-EMDPYKVLGVTRSASQAEIKKVYK---------------RLAKEWHPD KNKNPGAEDMFIKITKSYEILSSEDKRANYDRYGQTDDTQPYGGA-RYG-----HR--HDSFYFDESFNSFPFN------ ---SKHHRDFADNKYTLHFN--QYVNDVVPDSYKRPYLIKITSDWCFSCIHIEP----------------VWKEVVQEME TLGVGIGVVDVGHERRLANH--LGAHRTPSI---------LGVINGKVTFFHY----AVAKEHLRQFVEDLLPQRLVEWV -------TDKNDLQFLSSWHELNKPHVLLFDQVPEVPLLYKLTAFVYKDYLQFGYVDQG--------------------- ------------LSETANLQKEFNINTYAPTMLVFKENIDKPADIIQAKGMKKQIIDEFMSNNRFLLVPRLVNQKLFDEL CPVKQFHR-RRKYCVLLIT-----GDEETFTLGNH-AFLSFASTIT-------KEVVRFAYVYQRLQRPLCDVFTQSKDS AESSAQV-----------------VILERRNAAGKALFKPVTG-WNGSEE-------------DKRRLLEELERLQKDPS ILVHDAVLPELNNEFASMFAIR-WIYASYDYLSEVIDDILHNNWREMMPLLSLIFSALFI-----LFG---TVVIQAFS- ----------------------DSSEDVQTKPKAKDGSKAENGSPETGSAS----SRPPKKSFVEVTELTDITYMSNLVK LRPGHMNIVLVLTDASKNILLSKFAKEVYSFTGSLTLHFS-FLNMDKHGEWMFTLLEYAQ--------DATQIDADED-D GGNRKADYTGYVLALNGHKKYLCLFKPVYTGEDPDGK--SSEDEGAGSGGRS-----------------SRSKRSRSLST LQIHHKLDRLGLWMERLMEGTLHRYYIPTWPGLD---------------------------------------------- --------------------------------------------------------------------- >Gasterosteus_aculeatus_DNAJC16_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------LRRIRRYPRTLLL AIFLLILSV---------------QLVKAAS-EYDPYKILGVSRSASQAEVKKAYK---------------SLAKEWHPD KNKDPNAEDMFIKVSKSYEILSNEERRSNFDRYGQMDENQQFAQSQHQG-----FRGFHNSFYFDESFFHFPRSS----- ---SSRSRDFADSKYLLHHG--QFNTDVLPDSHKRPYLIKVTSEWCFACIHIEP----------------VWKETVLELE PLGVGIGIVDLGYERRLAHQ--LGAHRAPSI---------IGLVNGRVNFFHQ----AVVREHLRQFIEDLLPQKLVEKI -------TDDNYRVFLDSWRVENKPSVLLFDQIPIVPLLYKLTAFAFRDYVRFGFVDQG--------------------- ------------DTHNIQLLRQFNINTYAPTMLLFKEDSEKPVDIIQARGMKRQIMDEFVSNNKFLQVPRLVNQQLFDDL CPVKQFHR-RRKYCVLLIT-----GDDQAFHPGNK-AFLEFASANK-------KDVLRFAYVYQRQQQPLCQALLH--NQ AALSPQV-----------------VILERRSHAGKVMYRSVSGGWNGSEE-------------DKYHLHEQLELLQKDPT YLRSDATLPELNNEMAPVMLCRYWMNSAYDYIVQIYDDLLYSNWREMMPILSLIFSALFI-----LFG---TVIIQAFRG SCF----------------SEPGESKPRKPKPKEQP--QPEEDASSRGSTSS----RPPKKDFVEVTELTDITYISNLVK LRPGHINVVLVLTNASKNALLRKFAKEVFSFSGTQTLHFS-FLNADKHRHWMPSLLCSTS--------GAMR--REVHSD EDEESANYAGHVLALNGHKKYFCLFRPVFTGDNPNDS--SSETLFSSDSRRK---------------SRPRSRSSSHSRS RSHS----RLGLWMERLMEGTLLRLQVPAWPSLS---------------------------------------------- --------------------------------------------------------------------- >Oryzias_latipes_DNAJC16_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------------MTLAV AVVLAVLLT---------------PPARAAS-EMDPYKILGVTRSANSAEIKKVYK---------------RLAREWHPD KNKDPGAEDMFIKITKSYEILSSEDKRANYDRYGQTDDTQPYGSG-HYG-----HR--HDNFYFDESFFNFPFN------ ---NKNQRDFGDNKYTLHFN--HYINDVVPDSYKRPYLIKITSDWCFTCIHIEP----------------VWKEVVQEME SLGVGIGVVDVGYERRLANH--LGAHRTPSI---------LGVLNGKVTFFHY----AVAKEHLKQFVEDLLPQRLVEQV -------NDKNDQQFLNSWHDLNKPHVLVFDQVPVVPLLYKLTAFAYKDHLQFGYVDQG--------------------- ------------LTETADLQKRFNINTYAPTILVFKENIDKPADIIQAKGLKKQIVDEFMSNNKFLLAPRLVNQKLFDEL CPVKQFHR-RRKYCVLLIT-----GDEDIFAAGNQ-EFVSFASTNT-------KEVVRFAYVYQRLQQPLCDVLMQSRDG SPSTAQV-----------------VILERRNTAGKALFKPVTP-WNGREE-------------EKQLLLEELDRLQKDPS ILIHDAVLPALNNEFASMFVIR-WIYASYDYLSEVIDDILHNNWREMMPLLSLIFSALFI-----LFG---TVVIQAFSF LC-----------------PCSDSSADQLVKLTGKDGTTAENGS--SSSTS----SRPPKKNFVEVTELTDITYTSNLVK LRPGHMNIVLVLTDASKNILLSKFAKEVYSFTGSMTLHFS-FLNIDKHSEWMNTLLEYVQ--------DAMQIEADEEED GGNRKMDYTGHVLALNGHKKCFCLFKPVYTGEDVDGK--LSEDEGVTSGGRSRARSR------DDH-PARKSRRPRSTPT LQIHHKLDRLGLWMERLMEGTLPCYYVQTWPGIDKITSSK---------------------------------------- --------------------------------------------------------------------- >Oryzias_latipes_DNAJC16_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------KCHVVV AIFLLLLTV---------------DVVKATS-EYDPYKILGVSRSAGQAEIKRAYK---------------KLVREWHPD KNKDPKAEDMFIKISKSYEILSNEERRANFDRYGQMDENQPFGQSQHQG-----FHGFHRSFYFDESFFHFPR-F----- ---HLMSRDFADSKYMLHHA--QFNSEILPDSYKRPYLIKVTSDWCFACIHIEP----------------VWKEAVQELE PLGVGIGVVDLGYERRLANQ--LGAYRTPSI---------IGLVNGRVTFFHQ----VVVQEHLRQFVEDLLPQKLVEKV -------NDDNYLAFLESWHAENKPGLLLFDRVSDVPLLYKLTAFSFRDYMRFGYVEQG--------------------- ------------GTHITQLLQQFNINTFAPSMLLFKEDTQKPADIIQARGMKRQIMNEFVSNNKFLQVPRLVSQQLFDEL CPVKQFHR-RRKYCVLLIT-----GEDDAFLPGNK-AFLDFASAYK-------KDVLRFAYVYQRKQQPLCQALLQ--NQ AAVSPQV-----------------VILERRSQAGRVLFRSVSGGWNGSEE-------------DKHRLHEQLELLQRDPS YLTTDATLPELNNEMAPIFIVQ-WLSAVFDYILQIYDGLLYSNWREMMPILSLIFSALFI-----LFG---TVIIQAFS- --------------------EPGESKPQNPKQKESPTTQNEENPSSRASTSSEQ-SRPPKKDFVEVTELTDVTYTSNLVK LKPGHINVVLVLTNASKNTLLRKFAKEVFSFSGSQTLHFS-FLNADKHRHWMASLLRSAC--------FNHQ--SESHSD -DEDSPDCAGYVLALNGHKKYFCLFRPVFTGDNHSGS--SSETSFSSDSRRP---------------SRSRSRSSSHSRS RSHSSKLDRLGLWMERLMEGTLPRIQVPVWPTLD---------------------------------------------- --------------------------------------------------------------------- >Drosophila_melanogaster_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------MISCLISN---------------YIIT ILVLCTTSY---------------IHVC--SSLNDPYAILGINKKATTYEIREAYK---------------ELAKKWHPD KVKNDYGAEKFIQIKLAYEILADLDRRRIFDRYGVSDINSQYFQKKHDYSEYN-RFTLNQNDDDFGQRFDIK-QD----- ---IAFYQKLSITEN-------YFEKMILSKNAKKVHVVMFYNDWCFKCTRIVD----------------AFKKILELLQ PIGINFATVNAVHEESVFRK--CGAREVPQL---------VLILDNQYFLYRDH---SFTPQKVVEFIRKKIPFNVFKRI -------EHDNFNDFLGG-WSDNRARALIFEPRSLTRLRYLLTAFEFYDRVAFGFVNTIS-------------------- -------------KDSSNIITRFKVNTSLDTLILFNEDTTTFTASVCMEEIPNHILVNMVSTNQFLAFPRISSQNIMESV CPTEWNRQ-RKHLCVILIT-----E-NNRKKDFER-VALRNIALSVGYNSEK----VRFAYIFKESQPDFIKSISKGS-- FKDSLIE-----------------IVIIWRRDKKRIKYNWVY-----VAKQNGNSSPEHLMNSTKDQISNAVKKLLKNSE ALCYEAIVENLFNEHSQGILTK-WISQFLYVVDYLSDNIEDEHLLAVFSLLGTIAFMFTV-----GYV-----LIYFVR- -------------------------VEEKYLKAHG-HLIDIQDQRHINLIPELK-----------LYELRAEKYNGMVRL LKPGCRTLLLINDCQSRHKLIPYFHKAVWPYRKSKTLLFG-HMVIERGLPWFAEILRLSL-----------SKNRHLQ-- --VNPRNCVGTVLALNGHRKYFCMYHAKHPESALG--TKRTLKNTQKLLDANEDPEIGTFLKRDFSEESES-----EPNI LLEDNLLNGLDNWLERLFDGRTQKYYINYWPDFITK-------------------------------------------- --------------------------------------------------------------------- >Apis_mellifera_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------MLSINFLTFESINKRLNNINRKASYTELLMKFSFFIV IFIVTTYLL---------------SSVSGSESLGNPYKILGVHKRATLQEIRKAYK---------------NLVKEWHPD KTDHPGAENKFVEITKAYEILTDPERRKKFDNHGITEEN--ISRQRRDNSHFNNVFDPLEELFARNFKFHYQNRD----- ---ISLFYKMSITYR-------SFENVIVPKTFRTPYLILFYSDWCFACLQIEP----------------TWRRLIDELE PLGLGLATAHAEKESALARK--LGIHSLPCL---------VVTIDGRTSVYKES---LFSIQKIVDFLRSKFPYKLISNI -------NKNNIDSFLSG-WIDNRIRALIFDKKESVRLRYLFVAFYYRDRVAFGFVQMEK-------------------- -------------PETELIMTKYKISVDLDTLLLFNENSEKPMASVSMKDISSDTMHNIISNNKFLALPRLSNQAMLDSL CPPEWLRP-QKRLCAVLIS-----QQNSHFHDLAR-HKFRQAALESSYSTER----VRYTYVFKDTQPEFVSALSTGEGS PLEPLLH-----------------IVIIWRRDANHLKYEWLP------TGWIEAAQDESQWNETRRNLEQTIQRLLRASE ALPYAAVVGELADEHAQGTVDK-LIGKALLAVDYISDSLTKEQILPLVSVIATLMLIGAA-----GYG-----MSYLAK- -------------------------LEEASIQAERAQCKNNS--KPTPTQPQLR-----------LHELRAEKYNGLVRL LKPGCRTIILLVDDQSRLKLLPAFHKAVWPYRKNKTLMFG-HLSLERGLEWYKKLLSLTL-----------PEQKELN-- --INAKNCIGTVLSLNGHRKYFCMYHAKHPECIKGKGSKRIERMTKQLTRKTDDAEAGAFIGFDSSNESDVSEEENGNNI LCQDNLLDGLPMWLDRLFEGLTHRYYINYWPEFTAK-------------------------------------------- --------------------------------------------------------------------- >Anopheles_gambiae_DNAJC16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------MKTKAINNRHSKS--------LVYWIR LLVFFASIC---------------LSLS--ASS-DPYSILGVHKRASMQDIRRAYK---------------QLAKEWHPD KSKHPEAETRFVEIKQSYELLSDSERRRAFDQYGITNEDAVLDHNRPEYNNYG-RFKDTFEHFYGAHNFNYHDQD----- ---ISLYHRLSITTK-------YYETNIVPKSRHTPQIIMFYADWCFACMKAAN----------------SFKKLIDTLE PYGITFATVNAGHEEQLVRK--VGVHSLPCV---------IMVLNDHNYVYKDS---VFNPQHVVDFIRQKMPYKLLTPV -------TDNTLDKFLNG-WVDNRVRALILEPRMQPRLRYLITAYYFRERVVFGFVELNS-------------------- -------------KETAYIQAKFKAHPELDTLLIFNEFPPQPIATVTMSDIPSTTLNNIISLNKYLILPRLSSQDMLESV CPAEWNRP-RKKLCVVLVT-----E-NTRLHDGAR-TVMRKIALESLYNREK----VRFAYIYQEKQNDFISAFSKHNQ- SKETLLQ-----------------IIIFWRRDTKHIRYEWVDQTILEAEKVLENDTHDQYFNNTKQKLDSIIHRLLRSTE ALSFETEVKDLFDENSESSIMR-MLNRIILALEYISDNLGHEHILPAISVLGTVTFILII-----GYL-----MSYLLH- -------------------------LEEEDIQLNKSKRLENSNGKRISYIPELR-----------LHELRAEKYNGLVRL LKPGCRTIVLLTDLQSRSKLIPSFHKAVWPYRKNKTLMFA-HMLIEKGIGWYAELLRLSL-----------SECREMN-- --INPRNCIGTVVALNGHRKYFCMYHAKHPESNRG--AKRMIKITRHLSSMPTDPEAGAFLGMDSSDSETSVSDVFEPRI LLEENLLDGLPNWLDRLFEGTTHRYYINYWPDFTSK-------------------------------------------- --------------------------------------------------------------------- >Homo_sapiens_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLY---PLPSARALLEI IMKNG--------STAGNSPHCRKPSGSGDQSKPNCTKDST--------------------------------------- ---------------------S-GSGEGGKGYTKDQVDGVLSINKCKNYYEVLG------------------VTKDAGDE DLKKAYRKLALKFHPDKNH--APGATDAFK------------KIGNAYAVLSN-------PEKRKQ-YDLTGNEEQA--- -------CNHQNNGR--------FNFHRGCEA-DITPEDLFNIFFGG----GFPSG------------------------ -----------------------SVHSFSNGR---AGYSQQHQ-HRHSGHEREEER----GDGGFSVFIQLMPIIVLILV SLLSQLMVSNPPYSLYP-------RSGTGQTIKMQ--------------------------------------------- ---------------------------TENLGVVYYVNKDFKNEYKGM----------------------LLQKVEKS-- ------------------------------VEEDYVTNIRNNCWKERQQKTDMQYAAKV-------YR------------ -----------------------------------------------------------DDRLRRKADALSMDNCKELER LTSLYKGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Mus_musculus_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLY---PLPAARALLEI IMKNG--------STAGSSTHCRKPPGSSDQSKPSCGKDGT--------------------------------------- ---------------------S-GAGEGGKVYTKDQVEGVLSINKCKNYYEVLG------------------VTKDAGDE DLKKAYRKLALKFHPDKNH--APGATDAFK------------KIGNAYAVLSN-------PEKRKQ-YDLTGSEEQA--- -------CNHQNNGR--------FNFHRGCEA-DITPEDLFNIFFGG----GFPSG------------------------ -----------------------SVHSFSNGR---AAYSHQHQ-HRHSGHEREEER----ADGGFSVFIQLMPIIVLILV SLLSQLMVSNPPYSLYP-------RSGSGQTIKMQ--------------------------------------------- ---------------------------TENLGVVYYVSKDFKSEYKGT----------------------LLQKVEKS-- ------------------------------VEEDYVTNIRNNCWKERQQKTDMQYAAKV-------YR------------ -----------------------------------------------------------DEQLRRKADALSMENCKELER LTSLYKGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Canis_familiaris_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLY---PLPSARALLEI IMKNG--------STAGNSPHCRKPSGCGGQSKPNCTKDST--------------------------------------- ---------------------S-GGNEGGKGYTKDQIDGVLSINKCKNYYEVLG------------------VTKDAGDE DLKKAYRKLALKFHPDKNH--APGATDAFK------------KIGNAYAVLSN-------PEKRKQ-YDLTGNEEQA--- -------CNHQNNGR--------FNFHRGCEA-DITPEDLFNIFFGG----GFPSG------------------------ -----------------------SVHSFSNGR---AGYSHQHQ-HRHSGHEREEER----GDGGFSVFIQLMPIIVLILV SLLSQLMVSNPPYSLYP-------RSGSGQTIKMQ--------------------------------------------- ---------------------------TENLGVVYYVNKDFKNEYKGM----------------------LLQKVEKS-- ------------------------------VEEDYVTNIRNNCWKERQQKTDMQYAAKV-------YR------------ -----------------------------------------------------------DDRLRRKADALSMDNCKELER LTSIYKGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Gallus_gallus_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCIGIAREALEAGNRDRALRFLGKAQKLY---PTETARVLLEA ITKNG--------STAGGGAYCRKPASSNDQSKPSSTKEGN--------------------------------------- ---------------------ASAAGESGKGYTKDQMEGVFSMKKYKNYYEVLG------------------VSKDAGEE DLKKAYRKLALKFHPDKNH--APGATEAFK------------KIGNAYAVLSN-------PEKRKQ-YDLTGNEEQT--- -------CNHPSNGR--------FNFHRGCEA-DITPEDLFNMFFGG----AFPTG------------------------ -----------------------SVHSFSNGR---AGYSHPNQ-HRQSGHEREEER----GDGGFSMFIQLMPVIVLILV SLLSQLMVSNPPYALYP-------RSSTRQTIKMQ--------------------------------------------- ---------------------------TENLGVVYYVNKEFRNEYKGA----------------------SLQKVEKS-- ------------------------------VEEDYVSNIRNNCWKERQQKTELLHASKV-------YR------------ -----------------------------------------------------------DDRFRKKADSMSMENCKELER LTSLYRGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Xenopus_tropicalis_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MESNRDEAERCVRIAKAAIEAGDKEKAKRFLSKAERLY---PSSEARALLQA FEKN---------DTAGNGPQSAKMAKGTEQ--PKAEKDSN--------------------------------------- ---------------------ASASSDTGKGHTQDQLDGVQRIKKCKTYYEVLG------------------VSTDAGEE DLKKAYRKLALKFHPDKNH--APGATEAFK------------KIGNAYAVLSN-------PEKRKQ-YDLTGSEDQM--- -------QNNHRNGG--------FDYHRGFEA-DITPEDLFNMFFGG----GFPSG------------------------ -----------------------SVHTFSNGR---ARYSHHQH-HHHSGHDREDER----ADGGFSMFIQLMPIIVLILV SLLSQFMVSNPPYSLYP-------RSG--QATKRV--------------------------------------------- ---------------------------TENLQIAYYVSKDFQSEYSGI----------------------LLQKLEKN-- ------------------------------IEEDYVANVRNNCWRERQQRSDLMHAAKV-------YR------------ -----------------------------------------------------------DERLKVKAESISMENCKELNR LTSLFRGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Danio_rerio_DNAJB14_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAKKCLNIAVKAIEDGNKNKALKFLYKAEKLY---PTEKAKVLLEA LLNNG--------NSTGNSTAYCGKSSNGSKPGSQTQHEAPK-------------------------------------- --------------------QDSAAADLTKGFTKEQAEGVQRIKKCKNYYEVLG------------------IRKDASDD ELKKAYRQLALKFHPDKNH--APGATDAFK------------KIGNAYSVLSN-------PEKKRQ-YDLSGGEEPST-- -------PNYSSHEG--------FDFHRGFES-DITPEDLFNMFFGG----SFPSS------------------------ -----------------------NSHEFTNGR---TYSHHTEE-TRG---ERVEER----GDGGFSMFIQLMPIVVLVLV SILSQLLVSTPPYSLYS-------RPSTGQTVKRQ--------------------------------------------- ---------------------------TENLHVDYFVTTDFKSEYKGS----------------------ALLKIEKS-- ------------------------------VEEDYVSNVRNNCWKERQTKTDLLYAAKV-------YR------------ -----------------------------------------------------------DERLQRKAELMTMENCKELDR LNDLFRGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Takifugu_rubripes_DNAJB14_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCIHIATKALEAGDKEKALRFLNKAEKLY---PTEKAKKLLDA LTKNG--------SSAGNGAYRRRPAETSEHAGAHQDKEG---------------------------------------- --------------------QEPGALDASKGFTTEQVEGVQRIKRCKDYYEVLG------------------VGKDVGDE ELKKAYRKLALKFHPDKNH--APGATEAFK------------KIGNAYAVLSN-------PNKRRQ-YDLTGGEEPSS-- -------PGHSHGGG--------FDFHRGFEA-DITPEDLFNMFFGG----GFPSS------------------------ -----------------------SSHTFSHSR---RRNSHQTE-YQQ---ERTEER----GDGGFSMFIQLMPIVVLILV SLLSQMLVSPPTLQALTLD-----RMSTGQTVKRQ--------------------------------------------- ---------------------------TENLHVDYYVTRDFKSEYKAS----------------------ALQQIEKN-- ------------------------------VEEDYVSNVRNNCWKERQTKTDLLYAAKV-------YR------------ -----------------------------------------------------------DERMRKKAELMTMDNCKELDR LNSIFRGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Gasterosteus_aculeatus_DNAJB14_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MEGNRDEAEKCINIATKALQAGDKEKASKYLIKAEKLY---PTDRAKALLDA LTKNG--------SSAGNGAYRRRAADS---TGAQPGGEG---------------------------------------- --------------------QESGGGDSTKGFTKDQVEGVQRIKRCKDYYEVLG------------------VSKEVNED ELKKAYRKLALKFHPDKNH--APGATEAFK------------KIGNSYAVLSN-------PEKRRQ-YDLTGGEEPSS-- -------PGHSHGGGGGGG----FDFHRGFEA-DITPEDLFNMFFGG----GFPSS------------------------ -----------------------TTHTFTNSR---TSYSNQTD-NRQ---ERTEER----GDGGFSMFIQLVPIVVLILV SILSQMMVSPPPYSLYS-------RPSTGQTVKRQ--------------------------------------------- ---------------------------TENLHVDYYVSRDFKSEFKGS----------------------ALHQIEKN-- ------------------------------VEDDYVSNVRNNCWKERQTKTDLLYAAKV-------YR------------ -----------------------------------------------------------DDRMRKKAELMTMDNCRELDR LNNLFRGG------------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Drosophila_melanogaster_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLF---PTDNAKKLLAQ -------------LKSTPSNESNGKSRTAGASDEKDSGPRKR-------------------------------------- ----------------VNSD-SRSSAP---DYTKDQLEAVRKVKTCKDYYEVLG------------------VSKTATDS EIKKAYKKLALQLHPDKNK--APGAVEAFK------------ALGNAAGVLTD-------AEKRKN-YDLYGINESHNGH GNNGGGHHGHGQYYNNE------YGYSRGFQA-DISAEELFNMFFNG----GFPQQ------------------------ -----------------------NVHMR--------------QQR-RRQQAREDRE-----GNNSSALVNLLPIVLLIGL SMMSSFFISDPMYSLTP---------SHKYSVKRE--------------------------------------------- ---------------------------TNSLKVPYYVKDNFYSEYQG-----------------------SVARLEES-- ------------------------------VEEDFVNHLKHSCSRERNYRDSMLAKART-------FG------------ -----------------------------------------------------------DRDLYRKAQNINTPSCENLQK YLIT---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Apis_mellifera_DNAJB14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MDSNKDEAERCMELAELYLREKKYEEAEKFVRKALKLY---PMKKAEDVLAK -------------VTMLSKQNQKSE---SEPTLRKRQTASKE-------------------------------------- ----------------TTHT-QASS-----DYTKEQLEHIKRIKKCKDYYEILG------------------VNKDATDS DIKKAYKKLALQLHPDKNK--APGAAEAFK------------AIGNAVAILTD-------VEKRKQ-YDMYGPEEERL-- ------QSAQAHQNHSH------YNYTRGFET-DITAEELFSMFFGG----GFPQQ------------------------ -----------------------EFYMRRSGR---------WARQQDAQAQHAHSQQ----ANGYTTFLQMLPVLLLILL TMMSSFFISDPVYSLHS---------NAKYSVLRT--------------------------------------------- ---------------------------TQGLKVPYYVKENFHTEYQG-----------------------SLRRLEIS-- ------------------------------VEEEYLNNLRHACFREKSYRETMMWKARN-------FG------------ -----------------------------------------------------------DQELFFKAKNIETPSCKKVQE LQGA---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Homo_sapiens_RP11-762I7.5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------?PALQRCLTLLRDSRPWQRLVRIVQWGWLELPWVKQNINRQGN APVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDI VSNAEKRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDF WAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRIPGTRGRQRATPDAPPADLQDFLSRIFQV PPGQMPNGNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKLAELKQECLARG------------------LETKGIKQ DLIHRLQAYLEEHA---------------------------EEEANEEDVLGDE------TEEEETK--PIELPVKEEE- ------------------------PPEKTVDVA----AEKKVVKIT---------------------------------- -----------------------------------------SEIPQTERMQKRAER--------FNVPVSLESKKAARAA RFGISSVPTKG-------------LSSDNKPMVN---------------------------------------------- ------------------------------LDKLKERAQRFG---------------------------LNVSSISRK-- -------------------------------------SEDDEKLKKRKERFGIVTSSAG--T------------------ ------------------------------------------------------------GTTEDTEAKKR----KRAER FGIA---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Pongo_abelii_RP11-762I7.5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------MATETVELHKLKLAELKQECLARG------------------LETKGIKQ DLIHRLQAYLEEHA---------------------------EEEANEEDVLGDE------TEEEETK--PIELPVKEEE- ------------------------PPEKTVDVA----AEKKVVKIT---------------------------------- -----------------------------------------SEIPQTERMQKRAER--------FNVPVSLESKKAARAA RFGISSVPTKG-------------LSSDNKPMVN---------------------------------------------- ------------------------------LDKLKERAQRFG---------------------------LNVSSISRK-- -------------------------------------SEDDEKLKKRKERFGIVTSSAG--T------------------ ------------------------------------------------------------GTTEDTEAKKR----KRAER FGIA---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Taeniopygia_guttata_RP11-762I7.5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------MAAEPVELHKLKLAELKQECLARG------------------LEAKGNKQ DLIHRLQAYLEEHA---------------------------EEEPNEEDVLGEE------IEEEEPK--APEPPGKVEE- ------------------------APLKSPDVC----REE-GVKIS---------------------------------- -----------------------------------------SDISQMERMQKRAER--------FNVPVSLESKKAARAA RFGLATIPTKG-------------LAADSKPTLN---------------------------------------------- ------------------------------LEKLKERAQRFG---------------------------LNVSSLSRK-- -------------------------------------SEEDEKLKKRKERFGIVT---G--A------------------ ------------------------------------------------------------GAADDSE------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Takifugu_rubripes_RP11-762I7.5_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------KMAEVVELQKLKLAELRQECDARG------------------LATKGNKG ELIARLQAYLDEHA---------------------------EDDVDVDDVLVED------AEDFTK---SESDGVVNDIK ------------------------DPESSVETL----AEKKVVKIS---------------------------------- -----------------------------------------PASTASERLQKRAER--------FSLPASAESKKALRAA RFGLPAEGSGS----------SAGAAGDSKAPVN---------------------------------------------- ------------------------------IDQLKKRAERFG---------------------------MNVSTISQK-- -------------------------------------VEEDERLKKRKERFGALTSGRA--------------------- ------------------------------------------------------------AGAADTEAKKR----KRAER FGIV---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Gasterosteus_aculeatus_RP11-762I7.5_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------KMAEVIELQKLKLAELRQECEARG------------------LETKGNKG ELIARLQTYLDEHG---------------------------EDDVDVDDVLAED------AEVKDLDKVEDAINIKDEKT ------------------------SESTEQEPP----ADKKVVKIA---------------------------------- -----------------------------------------PPSSTGERLQKRAER--------FNMPATAESKKAIRAA RFGESTENSNP---------------AAGLAKVN---------------------------------------------- ------------------------------VDQLKKRAERFG---------------------------MNVSSVSQK-- -------------------------------------IEEDEKLKKRKERFGVSAVAG---------------------- ------------------------------------------------------------AGSAEVEAKKM----KRAER FGKV---------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Strongylocentrotus_purpuratus_RP11-762I7.5 --MAEQQQSPSGFKRMSLDKIIEAMTSDLESSNGHYVQFGVNPQQTTSHN----WGNYSSNQTRHYITSQSPHSNLPTMQ SMSPMG--------------------APLYMQDISNYDSPTDSIYFPSQTGVNHLGINENNDLIGTIDVGGGNYINVIYG N-------------------------------------------------ASQIMAEQCQLSNMTSYRNQNMIDREYGLF NDQHINIPPELPTQNFNGKQLIENLVGNWVPNQSG--------------------------------------------- --------TYSPFGGS------------SNVTSVVQSNVDIRDSEELPRNSTDSQHKKPRVVAEVKPMRPSYSDVLTKSA PTPPSPLTIQS-----------------IKPKTESVNKKISNKNSKNKSKSTTLKRQNSSGSDDHNSPKMQ------IPR KILEKNNSNLPRRWVSLDNLGSTTETHEINTFDRSNQFEKKK-------------------------------VSKMSKK IEKGETLNNSKIQNNNPKSIGNILKRPIQIN-------------------NNLNIINASSQTISPEKIEKNQQIVNKMNK EEKKATKEKNSKRFQTEKTQQIKKAQRNRRRENKE-----------------SPVKDLYKNLNKYASHWIKIGLKIFHWL LHLVSDVVSMSANLMILLAKCGWYHTILYLKYSWVYMAITFSKIRILN-IVGKQLDNWFG-NSKFAFWRKIKTK------ ----N---EEKEENSNWIHGGLEANIALPSTGEEAMKRLLACKGK--DPYSILG------------------VTPTCSDD DIKKYYKRQAFLVHPDKNNQ--PGAEEAFK------------ILVHAFDIIGE-------PERR----QAFDQTRQVEAA WGV----------------------LSDLLSQLHRKMEQAANTIRCT--------------------------------- -------------------------NCGLRHK-----RIPTQRPCYAARFCAQCKIRHSAKEGDIWAESRLMGFLWHYYA CMEGAVYDVT------------------DWAACQAGNL------------------------------------------ -----------------------KHLRANTHSVQYRIVLGQRPPSQTPNNGK--------RRQQIDPNTS---------- ---------------------------------EADFEDFLNN-----LYNHSKTGN----------------------- ---------------------------------------------------------------SSPPDQSSFRGDCKRRK TKRKK--------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Homo_sapiens_DNAJC14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAQ KHPGERGLYGAHHSGGASLRTLGPSVDPEIPSFSG--------------------------------------------- ----------------------------------------LRDSAGTAPNGTRCLTEHSGPKHTQHPNPAHWLDPSHGPP GGPGPPRDAEDPD----------------QSETSSEEESGVDQELSKENETGNQKDGN-SFLSIPSACNCQ-----GTPG IPEGPYSEGGNGSSSNFCHHCTSPALGEDE-LEEEYDDEESLKFPSDF-------------------------SRVSSGK KPPSRRQRHRFPTKEDTREGGRRDPRSPG--------------------RHRLGRKRSQADKRKGLGLWGAEELCQLGQA GFWWLIELLVLVGEYVETCGHLIYACRQLKSSDLDLFRVWMGVWTGRLGGWAQVMFQFLSQGFYCGVGLFTRFLKLLGAL LLLALALFLGFLQLGWRFLVGLGDRLGWRDKATWLFSWLDSPALQRCLTLLRDSRPWQRLVRIVQWGWLELP-------- -------WVKQNINRQGNAPVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLG------------------VEATASDV ELKKAYRQLAVMVHPDKNHH--PRAEEAFK------------VLRAAWDIVSN-------AEKRKEYEMKRMAENELSRS -------------------------VNEFLSKLQDDLKEAMNTMMCS--------------------------------- -------------------------RCQGKHR-----RFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFA LMDGKVYDIT------------------EWAGCQR--------------------------------------------- -----------------------VGISPDTHRVPYHISFGSRIPGTRGRQRA-----------TPDAPPADLQDFLSRIF QVPPG----------------------------QMPNGNFFAA---PQPAPGAAAAS----------------------- ------------------------------------------------------------KPNSTVPKGEA--KPKRRKK VRRPFQR------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Mus_musculus_DNAJC14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAQ KHPGERRLCGAHRSGGTSLSTSGSSVDPEILSFSG--------------------------------------------- ----------------------------------------LRDSAETAPNGTRCLKEHSGPKYTQPPNPAHWSDPSHGPP RGPGPPRGGGYPD----------------ESETGSEE-SGVDQELSRENETGYQEDGSPSFLSIPSACNCQ-----GSPG VPEGTYSEEGDGSSSSLCHHCTSPALGEDEELEEEYDDEEPLKFPSDF-------------------------SRVSSGK KPLSRRQKHRFLIKEDVRDSGRREPKAPG--------------------RHRLARKRSQTDKRRGLGLWGVEELCQLGQA GFWWLIELLVLVGEYVETCGHLIYACRKLKGSDLDLFRVWVGVWARRLGGWARMMFQFLSQSFFCVVGLLIRILRVVGAF LLLALALFLGCLQLGWRFSVGLGNRLGWRDKTAWLFSWLGSPALHHCLTLLKDSRPWQQLVRLIQWGWQELP-------- -------WVKQRTKKQGNAPVASGRYCQPEEEVTRLLTMAGVPEDELNPFHVLG------------------VEATASDT ELKKAYRQLAVMVHPDKNHH--PRAEEAFK------------ILRAAWDIVSN-------PERRKEYEMKRMAENELSRS -------------------------VNEFLSKLQDDLKEAMNTMMCS--------------------------------- -------------------------RCQGKHR-----RFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFA LMDGKVYDIT------------------EWAGCQR--------------------------------------------- -----------------------VGISPDTHRVPYHISFGSRVPGTSGRQRA-----------TPESPPADLQDFLSRIF QVPPG----------------------------PMSNGNFFAA---PHPGPGTTSTS----------------------- ------------------------------------------------------------RPNSSVPKGEA--KPKRRKK VRRPFQR------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Rattus_norvegicus_DNAJC14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAQ KHPGERGLCGVHHSGGSSLITSGSSVDPEILSFSG--------------------------------------------- ----------------------------------------LRDSKETAPNGTRCLKEHSDPKCTQPPNPAHWSDPSHGPP RGPGPPREGGYPD----------------ESETCSEE-SGVDQELSRENETGYQEDGSPSFLPIPSACNCQ-----GSPG VPEGTCSEEGDGSSSSFCHHCTSPALGEDEELEEEYDDEEPLKFPSDF-------------------------SRVSSGK KPPSRRQRHRFLTKEDVRDSGRRDPKAPG--------------------RHRLARKRSQTDKRRGLGLWGVEELCQLGQA GFWWLIELLVLVGEYVETCGYLIYACRKLKGSDLDLFRIWVGVWARRLGGWARVMFQFLSQSFFSVAGLFIRLLRVVGAF LLLALALFLGCLQLGWRFLVGLGDRLGWRGKAAWLFSWLDSPALHHFLTLLKDSRPWQQLVRVIQWGWLELP-------- -------WVKQRTQRQGTAHVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLG------------------VEATASDI ELKKAYRQLAVMVHPDKNHH--PRAEEAFK------------VLRAAWDIVSN-------PERRKEYEMKRMAENELSRS -------------------------VNEFLSKLQDDLKEAMNTMMCS--------------------------------- -------------------------RCQGKHR-----RFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFA LMDGKVYDIT------------------EWAGCQR--------------------------------------------- -----------------------VGISPDTHRVPYHISFGSRVPGTSGRQRA-----------TPESPPADLQDFLSRIF QVPPG----------------------------PMSNGNFFAA---PHPGPGTTSTS----------------------- ------------------------------------------------------------RPNSSVPKGEA--KPKRRKK VRRPFQR------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Anolis_carolinensis_DNAJC14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------MVWNGNC DQGGHGGLHFDSP----------------GPESSSCRCQGDVSDLSATYPETNFCDFTCRYWCSGVAGGKD-----TSRQ LQEEEEEEEEDT------------------EDGSAAKAKEELPNGTRG-------------------------ASVGRKV PRQQRHRPTVKGEGRFVLSSGGKHRPMRK--------------------RCDGGRHQVRAELLKHLERVASFCVSCF-KL FISLIVQVTHRCGEGVEASGKLLYSCCSFSPRDLDGMRSSIRTWIQQAGLSGRKLTRQLGLWVTLAYRLLKMLCAILFLV LMLLLGSLRLCWRVSKSALASLLGRLSHSSYGARLLSAVDLSL---IWTHVKDSRTCKWLAGVLLKWHALFWMP------ ----QRLRTTQEGDTTYNSSPGGSGPYQPGEEVARLLAMAHIPEEELNPFQVLG------------------LEATASDA ELKKAYRHLAVLVHPDKNKH--PRAEEAFK------------VLRAAWDIVSN-------PERRKEYEIKRMAETELTKS -------------------------MNEFLSKLQDDLKEAMNTMMCN--------------------------------- -------------------------KCQGKH-----KRFEMDRDPLNARYCAECSKLHAAEEGDFWAESSMLGLKITYFA MMDGKVYDIT------------------EWAGCQR--------------------------------------------- -----------------------VGISPDTHRVPYHISFGAR--GSGGRQRTK-----RAASEGSPASAAELQDFFNRIF QGNQG----------------------------QMPNGNFFST---PQQPPSSGTVPT---------------------- ------------------------------------------------------------PPAPPSKKGDS--KQKRRKK VRRPFQR------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Danio_rerio_DNAJC14_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------R-----KRMAATELSKS -------------------------MNEFLTKLQDDLKEAMNTMMCT--------------------------------- -------------------------KCEGKHK----R-FEMDREPGEARFCAECNKWHGAEEGDLWAESSMLGLRITFFA FMDGKVFDIT------------------EWAGCQR--------------------------------------------- -----------------------ISISPDTHRVPYHISFGSKGSSGPSRHRS------SSDHAAGGGSPADLQDFFNRFF Q------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------- >Takifugu_rubripes_DNAJC14_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------R-----KRMAATELSKS -------------------------MNEFLTKLQDDLKEAMNTMMCT--------------------------------- -------------------------KCEGKHR----R-FEMDRDPAEARFCAECKRCH