>Homo_sapiens_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVSEFLKQAWFIENEEQEYV----------------------------------------- -------------------------------------------------------------------QTVKSSKGGPGSA VSPYPT-FNPSSDVAALHKAIMVKG----------------------------------------VDEATI---IDILTK RNNAQRQQIKAAYLQETGKP-----LDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMK--GLGTDEDTLIEILASR TNKEIRDINRVYRE--ELKRDLAKDITSDTSGDFRN--ALLSLAKGDR-SEDFGVNEDLADSDARA-------------- -----LYEAGERRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDVNVFNTILTTRSYP--QLRRV--------F QKYTKYSKHDMNKVLDLELKGDIEKCLTAI---VKCAT-SKPAFFAEKLHQAMKGVGTRHKALIRIMVSR-SEIDMNDIK AFYQKMYGISLCQAILD--------ETKG-----DYEKILVALCGGN--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gorilla_gorilla_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVSEFLKQAWFIENEEQEYV----------------------------------------- -------------------------------------------------------------------QTVKSSKGGPGSA VSPYPT-FNPSSDVAALHKAIMVKG----------------------------------------VDEATI---IDILTK RNNAQRQQIKAAYLQETGKP-----LDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMK--GLGTDEDTLIEILASR TNKEIRDINRVYRE--ELKRDLAKDITSDTSGDFRN--ALLSLAKGDR-SEDFGVNEDLADSDARA-------------- -----LYEAGERRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDINVFNTILTTRSYP--QLRRV--------F QKYTKYSKHDMNKVLDLELKGDIEKCLTAI---VKCAT-SKPAFFAEKLHQAMKGVGTRHKALIRIMVSR-SEIDMNDIK AFYQKMYGISLCQAILD--------ETKG-----DYEKILVALCGGN--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Mus_musculus_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVSEFLKQARFLENQEQEYV----------------------------------------- -------------------------------------------------------------------QAVKSYKGGPGSA VSPYPS-FNVSSDVAALHKAIMVKG----------------------------------------VDEATI---IDILTK RTNAQRQQIKAAYLQENGKP-----LDEVLRKALTGHLEEVVLAMLKTPAQFDADELRGAMK--GLGTDEDTLIEILTTR SNEQIREINRVYRE--ELKRDLAKDITSDTSGDFRK--ALLALAKGDR-CQDLSVNQDLADTDARA-------------- -----LYEAGERRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDVNVFTTILTSRSFP--HLRRV--------F QNYGKYSQHDMNKALDLELKGDIEKCLTTI---VKCAT-STPAFFAEKLYEAMKGAGTRHKALIRIMVSR-SEIDMNEIK VFYQKKYGISLCQAILD--------ETKG-----DYEKILVALCGGN--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gallus_gallus_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVSEFLKQAWFMDNQEQECI----------------------------------------- -------------------------------------------------------------------KSSKG-----GSS VQSRPN-FDPSADVSALDKAITVKG----------------------------------------VDEATI---IDILTK RTNAQRQQIKAAYQQAKGKS-----LEEDLKKVLKSHLEDVVVALLKTPAQFDAEELRASMK--GLGTDEDTLIEILASR NNREIREASRYYRE--VLKRDLTQDIISDTSGDFQK--ALVILAKGDR-CEDPHVNDDLADNDARA-------------- -----LYEAGEKRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDVNVFITILTSRSYP--HLRRV--------F QKYAKYSKHDMNKVLDLELKGDIENCLTAL---VKCAT-SKPAFFAEKLHLAMKGSGTRHKQLIRIMVSR-HEIDLNEIK AYYKSLYGISLRQAIMD--------ELKG-----DYETILVALCGSDK-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Taeniopygia_guttata_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVSEFLKQAWFIENQEMECI----------------------------------------- -------------------------------------------------------------------KSAKG-----IHG VQSYPN-FDPSADVAALDRAITVKG----------------------------------------VDEATI---IDILTK RTNAQRQQIKAAYQQTKGKS-----LEEALKKALKGHLEDVVVALLKTPAQFDAEELRASMK--GLGTDEDTLIEILASR TNQEIREANRYYKE--VLKRDLTQDIISDTSGDFQK--ALVALAKADR-CENPHVNDELADNDARA-------------- -----LYEAGEKRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDTGVFITVLTKRSYP--HLRRV--------F QQYTKYSKHDMNKVLDLELKGDIENCLTAL---VKCAT-SKPAFFAEKLHLAMKGAGTRHKDLIRIMVSR-HEVDLNEIK GYYKSLYGISLRQAIMD--------ELKG-----DYETILVALCGSDN-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Anolis_carolinensis_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMVQEFLKMAYFMDTNEEQYV----------------------------------------- -------------------------------------------------------------------KNSKS-----GSA VHSYPS-FNPSADAAALDQAINAKG----------------------------------------VDEATI---IDICTK RNNAQRQQIKAAYQQLKGKP-----LEDALKKALKSHLEDVIMALLKTPAQFDAEELRWSMK--GLGTDEDTLIEILASR NNREIREASRAYQE--IFKRDLAKDIASDTSGDFQK--ACLALAKGDR-DENPHVNQELADNDARA-------------- -----LYEAGERRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDINCFISILTTRSPN--HLRSV--------F QKYSKYSKHDMNKVLDLELKGDIENCLTAI---VKCAT-SKPAFFAEKLHLAMKGSGTRHRTLNRIMVSR-SEIDMNEIK GFYKAMYGKTLAQAILD--------ETKG-----DYETTLVALCGGDN-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Pelodiscus_sinensis_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSMVQAFLKQAWFMDNEEQDCI----------------------------------------- -------------------------------------------------------------------KNSKA-----GSA VQTYPN-FNPSSDAAALDKAITAKG----------------------------------------VDEATI---IDILTK RTNAQRQQIKAAYQQSKGKS-----LEEALRKALKSPLEDVVLGLLKTPAQFDAEELRAAMK--GLGTDEDTLIEILASR NNRELKEIQRVYKE--EFKRDLLKDIASDTSGDFQK--ALLALAKGER-NEDGRVNEELADNDARA-------------- -----LYEAGEKRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDVATFINILTVRSFP--HLRRV--------F QKYTKYSKHDMNKALDLELKGDIESCLTAI---VKCAT-SKPAFFAEKLYLSMKGSGTRQKILNRVMVSR-SEVDMSEIK GYYNKLYGKSLCQAILD--------ETKG-----DYETILVALCCGDN-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Xenopus_tropicalis_ANXA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------SQKPGVGAEES-------------------------------------------- -----------------------------------------------------------------------------GPS LKANPG-FNAAADAANLDKAIKAKG----------------------------------------VDEGTI---IDILTK RTNCERQQIRAAYQQLTGKS-----LDDALKKCLKSHLEEVVLGLLKTPAQFDAHELRGAIK--GLGTDEDCLIEILVSR TNCEIKEINKVYKE--EFKKELGKDILGDTSGDFQK--TLLALSKGER-NEDTRVNEDQADNDARA-------------- -----LYEAGEKRKGTDVSTFINILTNKSYPHIQKVLQRYARYSKNDLNRAIDLEMKGDLEKCLMSIVKCASSKPAYFAE RFYLAMKGSGTRHNALIRVLVSRSEIDLKEIKTCYKRLYGKSLRQAIMEEKLKGDYETIMLALCGPDSNRAGHVSPHPDP KIFQTWDMVQSLQQQPSGGLKGAPGFNPSADAATLDKAIKTKGVDEATIIDILTKRNNAQRQEIKNAYQKSQVYKCELTK DLISDTSGDFQKALVALAKTDPVLFTGKAKMDKEPGNGSDREFLKKLLSSNVPEIAWLNQYKSIIHCDPELSRMSFLSQD KNKIYIQLLCGVCNRNGQQLLVQLNKNHLVLLTLFCQALYEAGEKRKGTDVNAFTTILTTRSFQ--HLQKV--------F MRYTKYSQHEMNKALDLELKGDIEKCLTAI---VKCAS-NRAAFFAEKLHEAMKGSGTRDKDLIRIMVSR-SEIDMNEIK AQYQRLYGKSLHQAILD--------DTKG-----DYETILIALCGGK--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Danio_rerio_ANXA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSFVSSFLEQLAYQGMQETT------------------------------------------- ----------------------------------------------------------------------VQDITEVQGT VKPYAQ-FNAAADAAVLDKAIKAKG----------------------------------------VDEPTI---IDTLVH RSNAQRQQIKAAYQQATSKP-----LDVALKNALKGELEDVVLGLLMTPAQYDAFQLKYAMK--GAGTTEDTLIEILASR TNKEIGDIKQVYKQ--EYKKDLEADIKSDTSGDFRN--ALLSLCKATR-SEDNIVKDDLADKDARA-------------- -----LYEAGEKRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GTDCSVFIDILTSRNGP--HLRKV--------F QQYNKYSKVDVAKAIDLELKGDIESCLIAV---VKCVS-NKPAFFAEKLNLAMKGSGYRGKILTRILVSR-SEIDLANIK QEYQKKYGKSLYQDIQD--------DTKG-----DYETILLALCGN---------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Takifugu_rubripes_ANXA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSLISAFLKQTIYMGMPDDSAT----------------------------------------- -------------------------------------------------------------------VRCVLKVLKREGT VVPAPN-FSASGDAAVLDKAIKVKG----------------------------------------VDEKTI---IDILVK RSNEQRQQIKEAYQQSSGKP-----LEAALKNALKGDLEDVVLALLKTPAQYDAQQLKLAMK--GIGTDEDTLIEILASR NNRELLDIKKAYKQ--DYKKDLEDDVRSDTSGDFRA--VLLEILKASR-TEV--VCDQLIDSDARA-------------- -----LYEAGEGRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GKDCAMFIEILATRSFP--HLRQV--------F DRYSKYSKVDVAKAIDLEMKGDIESCLTAI---VKCTG-SRPAFFAEKLNASMKGKGTRKNILTRIMVSR-SEIDMKQIK EEYKKNYGKSLYMDILD--------DTKG-----DYEKILLALCGDD--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Takifugu_rubripes_ANXA1_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSFFKKFFKNVIHDRDPDETVT----------------------------------------- --------------------------------------------------------------------VKGKKKPKYYGT IAPYPD-FDPRSDASNLQSSIESRG----------------------------------------VDEDVI---VSILVK RNNEQRQKIKVVYEATAGER-----LDKALKSALRSDLEDVSLALLMSPATFDAYLIRKATK--RLGTDEDVLVEIFATR TNKEILEIKSAFKE--EYNIDLEDVIRDETSGDFTT--ALLAMLQANK-DENGEVDTELARKDAEVQENKLLVRHVFVFV LLLQILFEAGENASG----------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------INVAAFIDILTRRSGP--QLCKT--------F QQYAALSDISLPKALDLELKGDIEDCLIDI---VKCAW-NTPAFFAEKLHKAMKGHGTCEDTLIRILVSR-SEIDLKKIL DEYRAMYDVSVQEDILN--------DTKG-----HYRDVLLGICGAH--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gasterosteus_aculeatus_ANXA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSFIQAFLQQTVYMGLPDDS------------------------------------------- -------------------------------------------------------------------------LLQKEGT VTAAPN-FNSSGDAGVLEQAIKAKG----------------------------------------VDENTI---IEVLVK RSNEQRQQIKDAYQKASGKS-----LESALKNALKGDLEEVVLALLKTPAHYDAQLLKLAMK--GLGTDEDVLIEILASR NNREIMDIKKAYKE--DYKKDLEADIKSDTSGDFRA--ALLELCKANR-TEG--VCEQMVDSDARA-------------- -----LYEAGEGRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GNNCSVFIEVLTSRSAP--HLRKV--------F ERYSKYSKVDMAKAIDLEMKGDIESCLTAV---VKCAG-SRPAFFAEKLYLAMKGKGTRKSILTRIMVSR-SEIDMKRIK DEYKKAYGATLYRAILD--------DTAG-----DYEKILLALCGSEN-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gasterosteus_aculeatus_ANXA1_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSFFKKFFKDVLRKADPADDTV----------------------------------------- -------------------------------------------------------------------KVKDNPKPKYYGT VTPYPN-FNASQDAATLQSAIKSKG----------------------------------------VDEDVI---IAILVK RNNEQRQKIKVVYEASTGKK-----LEADLKSVLRSDFEDVCLALLMDPTHYDAHLLRKATK--GFGTHEDILVEILATR SNQEIREIKRVFNE--VYKTELETVIQDETGGDFTS--ALLAMLKANK-DESKEVDMSLAQKDAEI-------------- -----LFEAGEKTKG----------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------INISVFIDILTKRSAP--QLSKT--------F QQYATVSDVKLPKALEMELRGDIEKCLIDIGL-VKCSW-NTPAFFAEKLHLAMKGIGTHDHTLIRVLVSR-SEVDLKKIV EEYRAMYSVSLQDDIVK--------DTKG-----HYQAILLGLCGAP--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Oryzias_latipes_ANXA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MSFIQAFLQQTVYLGMPDDS------------------------------------------- -------------------------------------------------------------------------VLRNEGT VTAAPN-FSPSGDAAVLDKAIKAKG----------------------------------------VDENTI---IEILVK RSNEQRQQIKEAYQQASGKP-----LESALKSALKGDLEEVVLALLKTPAQYDAQQLKLAMK--GLGTDEDTLIEILASR NNRQIMDLKKAYKE--DYKKDLEEDIRSDTSGDFRA--ALLALCKAGR-TEG--ISEQLIDSDARA-------------- -----LYEAGEGRK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------GKDCSVFIEILTTRSGP--HLRKV--------F ERYSKYSKVDMAKAIDLEMKGDIESCLTAI---VKCSG-SRAAFFAEKLNLAMKGKGTRKNILTRIMVAR-SEIDMKLIK EEYKKNYGKTLYKDILD--------DTKG-----DYEKILLALCGGDN-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Oryzias_latipes_ANXA1_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAMFKKFFNNIIHTKDSDNKKVPE--------------------------------------- -------------------------------------------------------------------PVKEKPKPKYYGT VTPHPD-FDASKDAGVLRSAIQSKG----------------------------------------VDEDVI---VAVLAK RNNEQRQKIKTVYEASVGKK-----LEQSLKDVLRSHLEDACLALLMPPANYDAHLLRKATK--GLGTDENVLVEILATR SNREIENIKRVFKE--EYKTELEEVIKDETSGDFTK--ALLAMLSAKK-DEGEKVDLELAQKDAKI-------------- -----LFEASGNSK------------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------INVSTFIEILTSRSGP--QLKKT--------F QHYASVSDTSLPKALELQLKGDIEDCLIDI---VKCAW-NTPAFFAEKLHNSMKGSGTRDNTLIRILVSR-SEVDLKKII EEYKAMFGRRLQEDIQK--------DTKG-----DYQQILLGLCGPH--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Homo_sapiens_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGD------------------------------------------- ----------------------------------------------------------------------HSTPPSAYGS VKAYTN-FDAERDALNIETAIKTKG----------------------------------------VDEVTI---VNILTN RSNAQRQDIAFAYQRRTKK-----ELASALKSALSGHLETVILGLLKTPAQYDASELKASMK--GLGTDEDSLIEIICSR TNQELQEINRVYKE--MYKTDLEKDIISDTSGDFRK--LMVALAKGRRAEDGSVIDYELIDQDARDLYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPKWISIMTERSVP--HLQKV--------F DRYKSYSPYDMLESIRKEVKGDLENAFLNL---VQCIQ-NKPLYFADRLYDSMKGKGTRDKVLIRIMVSR-SEVDMLKIR SEFKRKYGKSLYYYIQQ--------DTKG-----DYQKALLYLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gorilla_gorilla_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGD------------------------------------------- ----------------------------------------------------------------------HSTPPSAYGS VKAYTN-FDAERDALNIETAIKTKG----------------------------------------VDEVTI---VNILTN RSNAQRQDIAFAYQRRTKK-----ELASALKSALSGHLETVILGLLKTPAQYDASELKASMK--GLGTDEDSLIEIICSR TNQELQEINRVYKE--MYKTDLEKDIISDTSGDFRK--LMVALAKGRRAEDGSVIDYELIDQDARDLYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPKWISIMTERSVP--HLQKV--------F DRYKSYSPYDMLESIRKEVKGDLENAFLNL---VQCIQ-NKPLYFADRLYDSMKGKGTRDKVLIRIMVSR-SEVDMLKIR SEFKRKYGKSLYYYIQQ--------DTKG-----DYQKALLYLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Monodelphis_domestica_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MSTVHEILCKLNLEGD------------------------------------------- ----------------------------------------------------------------------HSTPPSAYGS VKAYNN-FDAERDALNIEAAIKTKG----------------------------------------VDEVTI---VNILTN RSNEQRQDIAFAYQRRTKK-----ELTSALKSALSGHLEAVILGLLKTPAQYDASELKASMK--GLGTDEDSLIEIICSR TNQELYEINKVYRE--MYKTELEKDIISDTSGDFRK--LMVALAKGRRAEDGSVIDYELIDQDARDLYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPKWISIMTERSVC--HLQKV--------F ERYKSYSPYDMLESIRKEVKGDLENAFLNL---VQCIQ-NKPLYFADRLYDSMKGKGTRDKVLIRIMVSR-SEVDMLKIR SEFKRKYGKSLYYFIQQ--------DTKG-----DYQKALLYLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gallus_gallus_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MSTVHEILSKLSLEGD------------------------------------------- ----------------------------------------------------------------------HSLPPSAYAT VKAYSN-FDADRDAAALEAAIKTKG----------------------------------------VDEVTI---INILTN RSNEQRQDIAFAYQRRTKK-----ELSAALKSALSGHLEAVILGLLKTPSQYDASELKAAMK--GLGTDEDTLIEIICSR TNQELNEINRVYRE--MYKTELEKDIISDTSGDFRK--LMVALAKGKRCEDTSVIDYELIDQDARELYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPKWINIMTERSVP--HLQKV--------F ERYKSYSPYDMLESIKKEVKGDLENAFLNL---VQCIQ-NKQLYFADRLYDSMKGKGTRDKVLIRIMVSR-CEVDMLKIK SEFKRKYGKSLYYFIQQ--------DTKG-----DYQRALLNLCGGED-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Taeniopygia_guttata_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MSTVHEILSKLSLEGD------------------------------------------- ----------------------------------------------------------------------HSLPPSAYAT VKAYSN-FDADRDAAALETAIKTKG----------------------------------------VDEVTI---INILTN RSNEQRQDIAFAYQRRTKK-----ELSAALKSALSGHLEAVILGLLKTPAQYDASELKAAMK--GLGTDEDTLIEIICSR TNQELSEINRVYRE--MYKTELEKDIISDTSGDFRK--LMVALAKGKRCEDTSVIDYELIDQDARDLYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPKWINIMTERSVP--HLQKV--------F DRYKSYSPYDMLESIKKEVKGDLENAFLNL---VQCIQ-NKQLYFADRLYDSMKGKGTRDKVLIRIMVSR-CEVDMLKIK SEFKRKYGKSLYYFIQQ--------DTKG-----DYQRALLNLCGGED-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Anolis_carolinensis_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------MSSWGPILRRGLGSGSKPLPGTGLGSGSKPLPGTDGSALPTVRSSC SSSSSSSCCCCSAAVSGHLSKMSTVHEILSKLTLEGD------------------------------------------- ----------------------------------------------------------------------HSLPPSAYAT VKAYGN-FDAERDAAALETAIKTKG----------------------------------------VDEVTI---VNILTN RSNEQRQDIAFAYHRSTKK-----ELPVALKSALSGHLETTILGLLKTPAQYDASELKAAMK--GLGTDEDTLIEIICSR TNQELHLINRVYKD--MYKTELEKDIISDTSGDFRK--LMVALAKGRRNEDVSVVDYELIDQDARELYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVAKWINIMTERSIP--HLQKV--------F ERYNSYSPYDILESIKKEVKGDLENAFVNL---VQCIQ-NKQLYFADRLYDSMKGKGTRDKILIRIMVSR-AEVDMLKIK SEFKRKYGKSLYYFIQQ--------DTKG-----DYQRALLNLCGGED-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Xenopus_tropicalis_ANXA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MSLIHEILGKLSLEGN-Q----------------------------------------- ----------------------------------------------------------------------SSTRQSTLGS VKASSN-FDAERDAAAIETAIKTKG----------------------------------------VDELTI---INILTN RSNEQRQDIAFAYHRKTKK-----DLPSALKGALSGNLETFMLGLIKTPPQYDASELKASMK--GLGTDEDSLIEIICSR TNKELLNIQNAYRE--LFKTELEKDIVSDTSGDFRK--LMVALAKGKRQEECNVVDYEKIDQDARELYE----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVNKWISIMTERSIP--HLQKV--------F ERYKSYSPYDMEESIKKEVKGDLENAFLNL---VQCIQ-NKPLYFADRLYDSMKGRGTKDKILIRIMISR-SESDMLKIR SEFKKKYGKSLHYFIGQ--------DTKG-----DYQRALLNLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Danio_rerio_ANXA2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MALVSEFLGQLTLELGGG----------------------------------------- --------------------------------------------------------------------------EPTYPT VVPEAN-FDPDKDAARIETAIKTKG----------------------------------------VDEQTI---IDILTK RTYNQRREIAFAYERRAKK-----DMISALKGALSGSLETVILGLMKSTAQYDASEIKASIK--GLGTDEESLIEILCSR SNAEIMEIKKVYRE--LFKKELEKDVAGDTSGDFAK--LLLALVEAKREQSSSVIDYQRIDEDARALYD----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVKCWISIMSERSVP--HLQKV--------F DRYKSYSPYDMQESIRKEVKGDLEKSFLTL---VQCFE-NKQLYFASRLQDAMKSKGAKEKVLTRIMVSR-CEVDLKKIR QEFKQHFGKSLHQTIAE--------HTKG-----DYQRALLSLCNGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Danio_rerio_ANXA2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MALVSEYLSKLTLSYGG------------------------------------------ ------------------------------------------------------------------------EREPKCPT VVAAYD-FNPEVDAAKIETAIKTKG----------------------------------------VDEQTI---IDILTR RSYLQRNDIAFEYEKRAKK-----DLVSALKGALSGSLEHLILGLMKSTPQYDAFELKASMK--GLGTDEESLIEMVCSR NKEELAEIKKVYKE--MFKKDLEKDISGDTSGDFAK--LLLALAQGKREEQSSVVDYEKIDNDARTLYE----------- --------TGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVVTWISIFSERSVS--HLQKV--------F ERYKRYSPYDIKESIRMEVKGDLEKSFLTL---VECLE-NKHLYFASRLNDAMKGKSVKDKIITRIIVSR-CEVDLMKVR IEFKRNFGRSLHQTISE--------HTKG-----DYQRALLNLVGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Takifugu_rubripes_ANXA2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MALVSEFLGQLTLSYGTVSDPL------------------------------------- ------------------------------------------------------------------SCNRKLEPEPTFPT VVPARD-FDPARDAARIDVAIKTKG----------------------------------------TDEQTI---IDILTR RSYEQRRDVAFEYERFAKK-----DLVTALKGALSGSLETLMLGLMKSTVQYDASELKASMK--GLGTDEETLIEIICSR NNEELTEIKKFYRE--MFKKELDKDIAGDTSGNFAK--LLLALVQTKRDEPSNVIDYEMIDNDARSLYE----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVTTWISIMSQRSVP--HLQKV--------F ERYKSYSPYDIQESIRKEVKGDLEKSFLTL---VDCFQ-NRQLYFANRLSEAMKSKGAKEKVVTRIIVSR-CEVDLKKIR SEFKRQHKKSLFQTIAE--------HTKG-----DYQRALLSLCGGD--------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Tetraodon_nigroviridis_ANXA2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MAMVSEFLGQLTLNAGSH----------------------------------------- --------------------------------------------------------------------------EPHFPT VVPALN-FDPNQDAARIETAIKTKG----------------------------------------VDEQTI---INILTK RTYSQRREIAFSYEKTAKK-----DMISALKGALSGSLESVILGLMKSTTQYDASEIRGSIK--GLGTDEETLIEILCSR SNTELMEIKKVYVE--LFKKELDKDVAGDTSGNFAK--LLLALVQAKRAEASSVVDFEKIDQDARALYQ----------- --------AGVGVKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPTWISIMSERSVP--HLQKV--------F QRYKSYSPYDMQESITKEVKGDLQKSFLVI---VQCIE-NKQLYFAKRLNEAMKGKGAKEKLLTRIIVSR-CEVDLKKIC SEYKSHFGQSLQKAITE--------HTKG-----DYQKVLLSLCGPEE-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Tetraodon_nigroviridis_ANXA2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MALVSEFLGQLTLSYGT------------------------------------------ ------------------------------------------------------------------------EPEATFPT VVPAPD-FDPARDAARMDTAIKTKAG---------------------------------------TDEQTI---IDILTR RSYEQRCEIAFEYERLAKK-----DLNSALKGALSGSLEALMLGLMKSAAQYDATELKSSMK--GLGTDEETLIEIVCSR SNQEMAEIKKVYRE--VFRKELDKDIAGDTSGNFAK--LLLALVQTKRDEPSNVIDYQMINADARSLYE----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DAA-WISIMSQRSVP--HLQRV--------F ERYQSYSPYDIKESIRKEVKGDLERSFTTL---VECFQ-NRQLYFANRLGEAMKSKGAKEKVVTRILVSR-CEVDLMKIR AEFRKLHQRSLFQTISE--------HTRG-----GYQRALLSLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gasterosteus_aculeatus_ANXA2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MAMVSEFLGQLTLSYGA------------------------------------------ ------------------------------------------------------------------------EVEPKFPT VVPERD-FDPSKDAARIETAIKTKG----------------------------------------VDEQTI---IDILTR RSTEQRREIAFEYERIAKK-----DLMTALKGALSGPLETLMLGLMRSTAQYDASELKASMK--GLGTDEETLIEIVCSR NYKELEEIKKVYKD--MFKKEVEKDIAGDTSGDFAK--LLLALVQTKRDEPSNVVDYEKIDEDARSLYE----------- --------AGVKRKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVATWISIMSQRSVP--HLQKV--------F ERYKRYSPYDIKESIRKEVKGDMEKSFLTL---VECFE-NRQLYFANKLNDAMKGKGAKEKVVTRIMVSR-CEVDLMKIR TEFKKQHKRSLYQTIAE--------QTKG-----DYQNALLSLCGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Gasterosteus_aculeatus_ANXA2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MAMVSEILGQLSLNIGAR----------------------------------------- --------------------------------------------------------------------------EPTFPT VVPAKD-FDPDKDAARIETAIKTKG----------------------------------------VDEQTI---IDVLTK RTYSQRTEIAFAYEKRAKK-----DMVSALKGALSGSLETVILGLMKSTTQYDASLIRGSIK--GAGTDEETLIEVLCSR SNNELVEIKKVYME--LFKKDLEKDVAGDTSGNFAK--LLLALVQTKRAEPSSIVDYEKIDEDARALYE----------- --------AGVKIKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVPTWISIMSERSVP--HLQKV--------F ERYKNYSPYDMQESIVKEVKGDLQKSFLVL---VKCFE-NKQLYFASKLNEAMKSKGAKEKSVTRIIVSR-CEVDLKKIC SEYKTNFGESLQKTILE--------HTKG-----DYQKVLLGLCGPEE-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Oryzias_latipes_ANXA2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MAMVSEFLGQLSLNETG------------------------------------------ --------------------------------------------------------------------------EIKYPT VVPVVN-FDPDKDAARIETAIKTKG----------------------------------------VDEQTI---IDILTK RTYSQRRDIAFAYERKTKK-----DMISALKGALSGSLESVILGLMKSTAQFDATEIKGSMK--GLGTDEETLIELLCSR SNSELVQIKSVYKD--LFKKELHKDVAGDTSGNFAK--LLLALVQTKRDEPSSVVDYGKIDEDARALYE----------- --------AGVKIKGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------DVATWISIMSERSVP--HLQKV--------F QKYRSYSPYDMQESIVKEVKGDLQKSFLVL---VQCIE-NKQLYFAKKLNEAMKSSGAKEKIVTRIIVSR-CEVDLQKIC SEFKSAFGKSLQETIEG--------HTKG-----DYQKALLSLCGPAA-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------- >Homo_sapiens_ANXA3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------MASIW----------------VGHRGT VRDYPD-FSPSVDAEAIQKA--IRGIG--------------------------------------TDEKML---ISILTE RSNAQRQLIVKEYQAAYGK-----ELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMK--GAGTNEDALIEILTTR TSRQMKDISQAYYT--VYKKSLGDDISSETSGDFRK--ALLTLADGRR-DESLKVDEHLAKQDAQILYK----------- --------AGENRWGT---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------D----EDKFTEILCLRSFP--QLKLT--------F DEYRNISQKDIVDSIKGELSGHFEDLLLAI---VNCVR-NTPAFLAERLHRALKGIGTDEFTLNRIMVSR-SEIDLLDIR TEFKKHYGYSLYSAIKS--------DTSG-----DYEITLLKICGGDD-------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------