>Homo_sapiens-PTPRT(ENSP_362294) -MASLAALALSLL----LRLQLPPLPGARAQSAAGGCSFDEHY---SNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTG S-FMMVNSSGRASGQKAHLLLP-TLKENDTHCIDFHYYFSSRDRS--------------SPGALN-VYVKVNGGPQGNPV WN--VSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CIAGGKWSQHDKLWLQ--QWNGRDTALMVTRVVNHRRFSATVS--VADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLT---RP GEG-GTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKIYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKIS-A PSMPEYDT-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERLQKS-RR-AADIIECFSVPVSYRNASSLDSLH YFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR RNAYSYSYYLS-------QRKLAKKQKETQSG--AQREMGPVASADKPTTKLSASRNDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RTCDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLLVLD---GDPHSDYINANYID------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQF---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Macaca_mulatta-PTPRT(ENSMMUP_1477) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------PVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKIYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKIS-A PSMPEYDT-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERPQKS-RR-AADIIECFSVPVSYRNASSLDSLH YFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR RNAYSYSYYFS-------KLKLAKKQKETQSG--AQREMGPVASADKPTTKLSASRNDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RTCDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLLVLD---GDPHSDYINANYID------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQF---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Mus_musculus-PTPRT(ENSMUSP_105068) -MGSLGGLALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHY---SNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTG S-FMMVNSSGRASGQKAHLLLP-TLKENDTHCIDFHYYFSSRDRS--------------SPGALN-VYVKVNGGPQGNPV WN--VSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CIAGGKWSQHDKLWLQ--QWNGRDTALMVTRVVNHRRFSATVS--VADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLT---RP GEG-GTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKIYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKIS-A PSMPEYDA-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERLQKS-RR-AADIIECFSVPVSYRNASNLDSLH YFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR --------------------KLAKKQKETQSG--AQREMGPVASTDKPTAKLGTNRNDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RTCDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLLVLD---GDPHSDYINANYID------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQL---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Oryctolagus_cuniculus-PTPRT(ENSOCUP_1... --------------------------------SAGGCSFDEHY---SNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTG S-FMMVNSSGRASGQKAHLLLP-TLKENDTHCIDFHYYFSSRDRS--------------SPGALN-VYVKVNGGPQGNPV WN--VSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CIAGGKWSQHDKLWLQ--QWNGRDTALMVTRVVNHRRFSATVS--VADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLT---RP GEG-GTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKMYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKIS-A PSMPEYDT-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERLQKS-RR-AADIVECFSVPVSYRNASSLDSLH YFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR RNAYSYSYYLS-------QRKLAKKQKETQSG--AQREMGPVASADKPTAKLSTSRKDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RTCDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISC---RCPL QRPQQQ----GDPP--LCFSPVIQ------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYIIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQL---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Bos_taurus-PTPRT(ENSBTAP_53345) ----------MSRLGTCLATLTGLLLTAAGDSFSGGCLFDEPY---STCGYSQAV-DDEFNWEQVNTLTKPTSDPWMPSG S-FMLVNTSGRPEGQRAHLLLP-QLKENDTHCIDFHYFVSSKSNS--------------APGSLN-VYVKVNNGPLGSPI WN--ISGDPNRTWNRAELAISTFWPNFYQVIFEVITS-GHQGYLAIDEVKVLGHPCTRTPHF-LRIQNVEVNAGQFATFQ CSAIGRTVAGDRLWLQ--GIDVQDAPLKEIKVTSSRRFIASFN--VVNTTKRDAGKYRCMIRTDGGVGISNYAELVVKEP PVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWSDRQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYKVG-------GQEQVR EEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELVVQTDED-LPGAVLTESIQGSTF-EEKIFLQWREPIE TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEL-ETPLNQ--TDSTVTVLLKPAHSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASILNSQY YFAAEFPANSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYFQAASRANGETKIDCVRVATK----------------- ----------GAATPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAQKRKETMSS-TRQEMTVMVSSMDKSYAEQGTSCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPD---------ETHTM---------------------ASDTSSLVQPHTY--KKREPA DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDH--HSR VRLQTVE---GD-NSDYINGNYID------GYHRPN--HYIATQG------PMQETISDFWRMVWHENTASIVMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--VHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNTG----- >Canis_familiaris-PTPRT(ENSCAFP_13647) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------ADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKIYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKIS-A PSMPEYDT-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERLQKS-RR-AADIIECFSVPVSYRNASSLDSLH YFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR RNAYSYSYYLS-------QRKLAKKQKETQSG--AQREMGPVASADKPTTKLSTSRNDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RACDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLLVLD---GDPHSDYINANYID------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVSLIETEPLAEYVIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--PSNYVNAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQL---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Loxodonta_africana-PTPRT(ENSLAFP_11399) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------ADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQQYEA EEVIQTS----SHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED-VPGAVPLESIQGGPF-EEKIYIQWKPPNE TNGVITLYEI--NYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRITTKIS-A PSMPEYDT-DTPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEERLQKS-RR-AADIIECFSVPVSYRNASNLDFLH YFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKAPMGSA--------QVT PGTPLCLLTTGASTQNSN------------------------TVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR RNAYSYSYYLS-------QRKLAKKQKETQSG--AQREMGPVASADKPTTKLSANRNDEGFSSSSQD--VNGF------- -------------------------------TDGSRGE---------------------LSQPTLTIQTHPY--RTCDPV EMSYPRDQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLLVLD---GDPHSDYINANYID------GYHRPR--HYIATQ------GPMQETVKDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDTMLD----MAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQL---CMQYWPE KTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -REGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----- >Gallus_gallus-PTPRT(ENSGALP_5463) ------------------------------------------------------------------------MDPAVPTG S-FMMVNSSGRASGQKAHLLLP-TLKENDTHCIDFHYYLSSRDRS--------------SPGSLN-VYVKVNGGPQGNPI WN--VSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CIAGGKWSQHDKLWLQ--QWNGRDTALMVTRVVNHRRFSATVS--VADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGNWAETHIVDSPNYKLWHLDPDVEYEIRVLLT---RP GEG-GTGPPGPPLTTRTKCADPVHGPQNVEVVDIRSRQLTLQWEPFGYAVTRCHSYNLTVQYQYVFN-------QQKFEA EELIQTS----SHYTLRGLRPFMTIRLRLALSNPEGKMESEELVVQTEED-VPGPVPLESIQGGPF-EEKIYVQWKPPNE TNGIITLYEI--TYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTVKGFGPPITTRIATKIS-A PSMPEYDT-DSPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEEKLQKA-RR-AADIIECFSIPVSYKNASSLDSPH YFAAELKPINLPVTQPFTVGDNKTYNGYWNAPLSPLKSYSIYFQALSKANGETKINCVRLATKG---------------- -----------ASTQNSN------------------------AVEPEKQVDSTVKMAGVIAGLLMFVIILLGAMLTIKRR RNAYSYSYYL----------KLAKKQKETQTS--TQREMGPVAASDKASAKLSAVHNEEAFSSSCQD--VNGFI------ -----------------------------FKTDSSHGE---------------------MTQPTLTIQTHPY--RSCEPV EMSYPRGQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLQLLD---GDPHSDYINANYID------GYHRPR--HYIATQVFSHAPGPMQETVKDFWRMIWQENSASVVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIREIRQFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDIMLD----MAENEGVVDIFNCVRELRSQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSIYYNISRIDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRCMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDAAQL---CMQYWPE KTSCCYGPIQVEFVSADIDEDIINRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -RDGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVESLEQYKFVYEVALEYLSSF----- >Taeniopygia_guttata-PTPRT(ENSTGUP_4545) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------QI--TYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTVKGFGPPITTRIATKIS-A PSMPEYDT-DSPLNE--TDTTITVMLKPAQSRGAPVS-VYQLVVKEEKLQKA-RR-AADIIECFSVPVSYKNASSLDSPH YFAAELKPINLPVTQPFTVGDNKTYNGYWNAPLSPLKSYSIYFQALSKANGETKINCVRLATKG---------------- -------------MWNSN------------------------AVEPEKQVDSTVKMAGVIAGLLMFVIILLGAMLTIKRR --------------------KLAKKQKETQTS--TQREMGPVAASDKTSTKLSAVHNEEAFSSSCQD--VNGFSNAQVPW TSLVQEDSLSPAEPSQHPCRVWGETALQTPCRRDTDGG---------------------LAQPTLTIQTHPY--RSCEPV EMSYPRGQFQPAIR---VADLLQHITQMKR--GQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSR VRLQLLD---GDPHSDYINANYID------GYHRPR--HYIATQG----KWPMQETVKDFWRMIWQENSASVVMVTNLVE VGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--YHEIREIRQFHFTSWPDHGVPCYATGLLGFVRQV KFLNPPEAGPIVVHCS-AGAGRTGCFIAIDIMLD----MAENEGVVDIFNCVRELRSQRVNLVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRSIYYNISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRCMDVLPLDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTITDFWRLVFDYNCSSVVMLNEMDAAQL---CMQYWPE KTSCCYGPIQVEFVSADIDEDIINRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDG- -RDGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVESLEQYKFVYEVALEYLSSF----- >Danio_rerio-PTPRT(ENSDARP_103477) ---------MDQRNYFALLLLVLHVQLTFGEFFPGSCSFEEHY---SNCGYSVALGTNGFAWEQVNTWERPSMDAAVPTG S-FMMVNASGRASGQKAHLLLP-TLKENDTHCIDFHYSLSSRDGT--------------SPGTLN-VYIKVDGGPQGNPI WN--ASTPVTEGWVKAELAISTFWPNSYQVIFEAVSVQGHPGFIAVDEIHVLAHPCRKTPHF-LRLQNVEVNVGQNATFQ CIAGGKWSQHDKLWLQ--QWNGKDTSLMVTRVVNHRRFSATVS--VTDTSQRSTSRYRCVIRSDGGSGVSNYAELSVKAP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGNWAETHVVDAPTYKLWHLDPDVEYEIKVLLT---RP GEG-GTGPPGPPLITRTKCADPVNGPQNVNVVDIRARQLTLQWETFGYAVTRCHSFNLTVQYQYVFN-------QQVYAT EDLIPTS----SHYTLRGLRPFVTVRLRLVLANPEGSKESEEIVKQTEED-VPGPIPMESIQTGPY-EEKIFMQWKAPNE TNGVITLYEI--AYKALSSLDPTADLTTQRGRVFKLQNETHHLFVGLYPGTTYFFTLKASTNKGFGPPVTTRITTKIA-A PSMPEYET-DSPLNE--TDTTITVLLKPAQSRGAPVS-SYQVVVQEERKQKV-RR-ATDVLECFPVPVSFRNASILDSPH YFAAELPPVSLAVVQPFTIGDNKTYNGYWNAPLSPAKSYSIYFQALSKANGETKINCVRLATKVVIGRG--------QNT TPYILVIPSEGASTQNSN------------------------DIEPEKQVDSTVKMAGVIAGILMFVIILLGLLLTFKR- RNAYSYSYYLK----------LAKKQKETASSSTQR-EMGPVGTADKSTGKVSTLHKDDPFSTSNQD--LNGFSSSS-PC SFSIQGKAIQSKTLLNSYYSVSKEPVPATASIDGSHSE---------------------MSQPSMTIQTYPY--GGCESV EMSYQAGQFQPAIR---VADLLQHITQMKC--GQGYGFKEEYEGLAEGQTAPWETAKKEENRNKNRYGNIIAYPTDDHTR VRLQPLE---GDPHSDYINANYID------GYHRPR--HYIATQG------PMQETVRDFWRMIWQENSASIVMVTNLVE VGRVKCVRYWPDETEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--HHEIREIRQFHFTSWPDHGVPCYATGLLGFIRQV KFLNPPDAGPIVVHCS-AGAGRTGCFIAVDIMLD----MAESEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRAIYYNISRLDPQTNSSQVKDEFQT---LNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLAVDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTMADFWRLVFDYNCSTIVMLNEMDAAQL---CMQYWPE KGSCCYGPIQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKRSILQLVRRLAKWQEQYDG- -GDGRTVVHCLTGGGRSGTFCAICSICEMIQQQNIVDVFHTVKTLRNNKANMVETMEQYKFCYEVALESLNGF----- >Oryzias_latipes-PTPRT(ENSORLP_12273) ----------------------------------GGCTFEESY---SSCGYSVSLGTNGFTWEQVNSWEKTTLDPALPTG S-YMVVNASGRASWQKAHLYMP-VLKENDTHCIDFLYSLSSRDGA--------------SPGTLN-VYIKVNGGPQGNPV WN--ASDTVTEGWVKAELAISTFWPNSYQVIFEAVSVQGHPGYIAVDDIRVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CTAGGKWSQQDKLWLQ--QWNGKDTALMVTRVVNHRRFSATVS--VGDTSQRSTSRYRCVIRSDGGSGVSNYADLIVKAP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTAGNWAETHVVDSPTYKLGHLDPDVEYEIKVLLS---RP GEG-GTGPPGPPLVTRTKCADPVHGPQNVNVVDVRARQLTIQWETFGYAVTRCHSYNLTVQYQYVFN-------QQEFAA EELIQTS----SHYTLRGLRPFVTVRLRLVLANPEGSKESEEIVKQTEED-VPGSVPMESLQNTPY-EEKIFMQWKTPNE TNGAITLYEI--TYKALSSLDPSADLTTQRGRVFKLRNETHHMFVGLYPGTTYFFTLKASTNKGFGPPVTNRITTKIA-A PMMPEYDS-ESPLNE--TETTITVLLKPAQSRGAPIS-SYQLVVKEERKSKT-RRAAPEGLECFSAPVSFRNASILDSPY YIAADLPPSSLTVVQPFTVGDNKSYGGFWNPPLSPAKSYSIFYQAMSRANGETKINCVRLAHKDTVVTC--------QIQ PPLPLVLRTVGASTQDSD------------------------AMEPEKQVDSTVKMAGVIAGILMFIIILLGLVLTFKRR RHAYSYSYYLS-------LRKLAKKQKETASSSTQQREMGPVTTADKSTTKVSTLHKDDPFSTSNQD--LNGFIT----- --------------------------------DSSQPS---------------------LSQPSLTLQSFPY--GGCESV ELSYQSGQFQPAIR---VADLLQHITQMKC--GQGYGFKEEYEALAEGQTAPWETAKKDENRNKNRYGNIIAY---DHTR VRLQLLD---GDPHSDYINANYID------GYHRPR--HYIATQG------PMQETVRDFWRMVWQENTASIVMVTNLVE VGRVKCVRYWPDETEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--HHEIRELRQFHFTSWPDHGVPCYATGLLGFIRQV KFLNPPDAGPIVAHCS-AGAGRTGCYIAVDIMLD----MAENEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEAC LCGNTAIPVCDFRAIYYNISRIDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSVGLLPRNHDKNRSMDVLPADRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTISDFWRLVFDYNCSSIVMLNEMDAAQL---CMQYWPE KNSCCYGPIQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKRSILQLVRRLAKWQEQYDG- -GDGRTVVHCLTGGGRSGTFCAICSINEMIQQQNIVDVFHTVKTLRNNKTNMVETMEQYKFCYEVALEALNSF----- >Takifugu_rubripes-PTPRT(ENSTRUP_21083) ----------------------------------GGCTFEESF---FNCGYSVSLGTTGFTWEQVYSWRTPTMDPAMPTG S-FMLVNASGRASGQMAQLYMP-TMKENDTHCINFLYSLSSHDGT--------------SPGTLN-VYVQVDGGSRGNPV WN--ISGTVTEGWVKGELAISIFWPNSYQITFEAVSIKGHPGFIAISEIRVVPHPCRETPHF-LRLQNVEVNVGQNASFE CIAAGKWSQHDKLWLQ--QCNGKDTALMMTRVVNHRRFSSMVN--VGDTSKHGTSQYRCVVRSNGGSGVSSYANLSVKAP PSPIAPPELLNVGATYLWIKPNANSIIGDGPIISKEVAYRTTSGNWCETFAVDSPTYKLWHLDPDVEYEIKVILS---RP GEG-GKGPPGPPLITRTKCADPVQGPQNVNVVDVRARQLTIQWETFGYAVTRCHAYNLTLQYKYMYN-------QMEFGT EEVIRTS----SHYTLRGLRPFVTVWLRLILANTEGSKQSEEIVKQMDSD-VPSSIPKESLLKTVS-EDNIIMQWEAPTE PNGIITKYEI--TYNALSSSDPSADVTNQRGRIFKLSNETSHVFHGLYPGTTYIFTIKASTIKGFGPPVSITIITKIA-A PIMPEYKS-ETALNE--TDTTITILLKPAQPYGAPIR-SYQLIVKENR-TRS-RRDALKSPECFSIPVSFRNASVLDSPY YIAAELLPPSLSIVQPFTVGDNKSYGGFWNSPLSPVKSYSIYLQATSRTNGETTINCVRMANKVVIGRG--------QKT TPYILVIPSEAASIQDSG------------------------DMELDKQGNRKMKMVGVIIGILLFVIILLGIIFTFKRK RHAYSYSYYLS-------QRKLAKKQKETASSSTQQIEMAPVTAANTSTVNVVILHKDDPFSISGQD--LGGFT------ --------------------------------DSSQPS---------------------LAQSSLSLQSFPY--GECESV EVSYQSGQFQPAIR---VADLLQHITQMKC--GQGYGFKEEYEALAEGPTAPWETAKKDANQSKNRCGNIIAY---DHSR VRLQLLD---GNLHSDYINANYIN------GYSQPR--HYIATQG------PMQETVRDFWRMVWQENTSSIVMVTNLVE VGRVKCVRYWPDETEIYGDIKVTLTETEPLAEFVIRTFTVQKKG--YHDIREVRQFHFTSWPDHGVPCYATGLLGFIRQV KFLNPPGTGPIVAHCS-AGAGRTGCFIAVDFLLD----MAENEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEAC LC-NTAIPVCEFRAIYYDISRLDPQTNSSQIKDEFQT---LNIVTPRVLPEDCSVGLLPRNHDKNRSLDGLPADRCLPFL ISVDGD--RSNYINAALMDDSVYTQSHKQPAAFIVTQHPLPNTMGDFWRLVFDYNCSSIVMLNEIDAKQL---CMQYWPE KSSCRYGPIQVDLISADIDENIINRIFRICNMARPQDGYRVVKHFHFIGWPAQRDTPLSKRSILQLVQRLAKWQKQYDG- -GDGRTVVHCLTGGGRSGTFCAICSISEMIKQQNIIDVFHTVKTLRNNKTNMVETVEQYKFCYEVALEELNSF----- >Tetraodon_nigroviridis-PTPRT(ENSTNIP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------ISRLDPQTNSSQIKDEFQT---LNIVTPRVRPEDCSVGLLPRNHDKNRSLDVLPTDRCLPFL ISVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTMGDFWRLVFDYNCSSIVMLNEMDAAQL---CMQYWPE KSSCCYGPVQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKRSILQLVRRLAKWQEQYDG- -GDGRTVVHCLTGGGRSGTFCGICSINEMIQQQNIIDVFHTVKTLRNNKTNMVETMEQYKFCYEVALEALSSF----- >Gasterosteus_aculeatus-PTPRT(ENSGACP_54) -------------------------------SLPGGCTFEEPY---SSCGYSVSLGTSGFSWEQLNSWEKPTMDPALPTG S-FMMVNGSGQASGQKAHLYMP-TLKENDTHCIDFLYSLSSRDGG--------------SPGTLN-VYIKVNGGTQGNPV WN--ASNTITEGWVKAELAISTFWPNSYQVIFEAVSVQGHWGFIAVDDIQVLAHPCRKAPHF-LRLQNVEVNVGQNATFQ CTAGGKWSQHDKLWLQ--QWNGRDTAFMVTRVVNHRRFTATVR--VGDTSQRSTSRYRCVIRSDGGSGVSNYADLIVKAP PTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTSGNWAETHVVDSPTYKLWHLDPDVEYEIKVLLS---RP GEG-GTGPPGPPLVTRTKCADPVHGPQSVNVVDVRARQLTIQWETFGYAVTRCHSYNLTVQYHYAFN-------QQEFAA EELIQTS----SHYTLRGLRPFVTVRLRLVLANPEGSKESEEIVKETEED-VPASVPMESLQNTAY-EEKIFMQWKAPNE TNGVITLYEI--TFKALSSLDPSADLTTQRGRVFKLRNETLHFFVGLYPGTTYFFTIKASTNKGFGPPITTRISTKTS-A PMMPEYES-EAPLNE--TETTITILLKPAQSRGAPIS-SYQLVVKEERKSKT-RRAASNPFDCFSAPISFRNASFLDSSY YMAAELPPPSLAVVQPFTVGDNKSYGGFWNPPLSPAKSYVIYYQAVSRANGETKINCVRLANKVPLHTAGTTP----SVR PGIRLYVITLGASTQDSG------------------------AMEPEKQVDSTVKMAGVIAGILMFIIILLGVVLAFKRR RHAYSYSYYLLH------HRKLAKKQKETTSSSTQQREMGPVTTADKSTTKVSTLHKDDPFSTSNQE--LNGFT------ --------------------------------DSSQPS---------------------LSQPSLTLQSFPY--GGCESV ELSYQSGQFQPAIR---VADLLQHITQMKC--GQGYGFKEEYEALAEGQTAPWETAKKDENRNKNRYGNIIAY---DHTR VRLQLLD---GDPHSDYINANYID------GYHRPR--HYIATQAG-----PMQETVRDFWRMVWQENSASIVMVTNLVE VGRVKCVRYWPDETEVYGDIKVTLIETEPLAEYVIRTFTVQKKG--HNEIRELRQFHFTSWPDHGVPCYATGLLGFIRQV KFLNAPDAGPIVAHCS-AGAGRTGCFIAVDIMLD----MAETEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEAC LCGNTAIPVCEFRAIYYNISRLDPQTNSSQIKDEFQVNQTLNIVTPRVRPEDCSVGLLPRNHDKNRSMDVLSADRCLPFL IAVDGE--SSNYINAALMD------SHKQPAAFIVTQHPLPNTMADFWRLVFDYNCSSIVMLNEMDAAQL---CMQYWPE KSSCCYGPIQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKHSILQLVRRLAKWQEQYDG- -GDGRTVVHCLTGGGRSGTFCAMCSINEMIQQQNIVDVFHTVKTLRNNKTNMVETMEQYKFCYEVALEALSSF----- >Homo_sapiens_PTPRM(ENSP_331418) ----------MRGLGTCLATLAGLLLTAAGETFSGGCLFDEPY---STCGYSQSE-GDDFNWEQVNTLTKPTSDPWMPSG S-FMLVNASGRPEGQRAHLLLP-QLKENDTHCIDFHYFVSSKSNS--------------PPGLLN-VYVKVNNGPLGNPI WN--ISGDPTRTWNRAELAISTFWPNFYQVIFEVITS-GHQGYLAIDEVKVLGHPCTRTPHF-LRIQNVEVNAGQFATFQ CSAIGRTVAGDRLWLQ--GIDVRDAPLKEIKVTSSRRFIASFN--VVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEP PVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG-------GQEQVR EEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDED-LPGAVPTESIQGSTF-EEKIFLQWREPTQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEL-ETPLNQ--TDNTVTVMLKPAHSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASLLNSQY YFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATK----------------- ----------GAATPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPD---------ETHTM---------------------ASDTSSLVQSHTY--KKREPA DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTIE---GDTNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--VHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPSAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Macaca_mulatta-PTPRM(ENSMMUP_1036) -----------------------------------GCLFDEPY---STCGYSQSE-DDDFNWEQVNTLTKPTSDPWMPSG S-FMLVNASGRPEGQRAHLLLP-QLKENDTHCIDFHYFVSSKSNS--------------PPGLLN-VYVKVNNGPLGSPI WN--ISGDPTRTWNRAELAISTFWPNFYQVIFEVITS-GHQGYLAIDEVKVLGHPCTRTPHF-LRIQNVEVNAGQFATFQ CSAIGRTVAGDRLWLQ--GIDVRDAPLKEIKVSSSRRFIASFN--VVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEP PVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG-------GQEQVR EEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDED-LPGAVPTESIQGSTF-EEKIFLQWREPTQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEL-ETPLNQ--TDNTVTVMLKPAHSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASLLNSQY YFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYFQAASRANGETKIDCVRVATK----------------- ----------GAATPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPD---------ETHTM---------------------ASDTSSLVQSHTY--KKREPA DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTIE---GDTNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKVMSVHHSSPCCERFQDTGKPQHGVDSHLT------RHL KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQV---------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------ >Mus_musculus-PTPRM(ENSMUSP_45603) ----------MRTLGTCLVTLAGLLLTAAGETFSGGCLFDEPY---STCGYSQAD-EDDFNWEQVNTLTKPTSDPWMPSG S-FMLVNTSGKPEGQRAHLLLP-QLKENDTHCIDFHYFVSSKSNA--------------APGLLN-VYVKVNNGPLGNPI WN--ISGDPTRTWHRAELAISTFWPNFYQVIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHF-LRIQNVEVNAGQFATFQ CSAIGRTVAGDRLWLQ--GIDVRDAPLKEIKVTSSRRFIASFN--VVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEP PVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVG-------GQEQVR EEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDED-LPGAVPTESIQGSAF-EEKIFLQWREPTQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEF-ETPLNQ--TDNTVTVMLKPAQSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASILNSQY YFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATK----------------- ----------GAVTPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYAEQGTNCDEAFSFMGTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPD---------ETHTM---------------------ASDTSSLAQPHTY--KKREAA DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQMLE---GDNNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIDTELLAEYVIRTFAVEKRG--IHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Oryctolagus_cuniculus-PTPRM(ENSOCUP_1... ----------------------------------GGCLFDEPY---STCGYSQAE-DDDFNWEQVNTLTKPTSDPWMPSG S-FMLVNTSGRPEQQTAHLLLP-QLKENDTHCIDFHYFVSSKSNS--------------APGLLN-VYVRVNNGPLGNPI WN--ISGDPTRTWNRAELAISTFWPNFYQVIFEVVTS-GHQGYLAIDEVKVLGHPCTRTPHF-LRIQNVEVNAGQFATFQ CSAIGRTVAGDRLWLQ--GIDVRDAPLKEIKVTSSRRFIASFN--VVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEP PVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG-------GQEQVR EEVSWDPDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQALVVQTDED-LPGAVPTESIQGSTF-EEKIFLQWREPTQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEL-ETPLNQ--TDNTVTVMLKPAQSRGAPVS-VYQIVVEEERPRRT-KK-TTEVLKCYPVPIHFQNASILNSQY YFAAEFPADSLQAAQPFTVGDNKTYSGYWNTPLLPHKSYRIYFQAASRANGETKIDCVRVATK----------------- ----------GAATPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPD---------ETHTM---------------------ASDTSSLVQSHTY--KKREQT DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTIE---GDTNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--VHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCSSAGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLALDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRSVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Canis_familiaris-PTPRM(ENSCAF_27527) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------DPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVG-------GQEQVR EEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDED-LPGAVPTESIQGSTF-EEKIFLQWREPIQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKIS-A PSMPAYEL-ETPLNQ--TDNTVTVMLKPAHSRGAPVS-VYQVVVEEERPRRT-KK-TTEILKCYPVPIHFQNASILNSQY YFAAEFPANSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYFQAASRANGETKIDCVRVATKAAIIVTQLTTPYIRIAP AAGDDQLTASGAATPKP-------------------------VPEPEKETDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPNS-YYPDPFVPTAILDESHTM---------------------ASDTSSLVQSHTY--KKREPA DVPYQTGQLHPAIR---VADLLQHITQMKC--AESYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTIE---GDTNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--VHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Loxodonta_africana-PTPRM(ENSLAFP_6761) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------DPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYNVG-------GQEQVR EEVSWDTDSSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDED-LPGAVPTESIQGSTF-EEKIFLQWREPTQ TYGVITLYEI--TYKAVSCFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNKFTTKIS-A PSMPAYEL-ETPLNQ--TDNTVTVLLKPAQSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASLLNSQY YFAAEFPANSLQAAQPFTIGDNKTYSGYWNTPLLPHKSYRIYFQAASRANGETKIDCVQVATK----------------- ----------GAATPKP-------------------------VPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETMSS-TRQEMTVMVNSMDKSYTEHGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTSVPHS-HYPD---------ETHTM---------------------ASDTSSVVQSHTY--KKREPA EVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTVE---GDTNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWYENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--IHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRAVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Gallus_gallus-PTPRM(ENSGALP_22500) ------------------------------------------------------------------------------AG S-FMLVNTSGRYAGQKAHLLIP-HLKENDTHCIDFHYYVSSKSGS--------------SPGTLN-VYVKVNDGPIGNPV WN--TS--TTGTWNRAELAISTFWPNFYQVVFEVVTS-GHPGYVAIDEVKVLGHPCTKTPHF-LRLQSVEVNAGQFATFQ CTANGKFSTSDRLWLQ--GIYVRDAPLKNTKVFNIRRFVALFN--VVNATKRDAGNYRCMIRTEGGVGVSNYAELIVKEP PVPIAPPQLSSVGATYLWIQLNANSINGDGPIIQREVEYRTSSGSWYDIQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALKTRTKCADPMRGPRKLEVVEIKSRQITICWEPFGYNVTRCHRYNLTVHYRYQAG-------GQEQVR EEVSWDTESSHPQHTITNLSPYTNVSIKLVLMNPEGRKESQELVVQTDED-VPSAVPLESIQGSTF-EEKIFLQWREPVQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHYLFFGLYPGTTYSFTIRASTAKGFGPPITNQFTTKIS-A PSMPPYEL-ETPLNQ--TDSTVTVLLKPAQSRGAPVS-VYQIVVEEERPRRT-KK-TTEILKCYPVPIHFQNASLLNSRY YFAAEIPANGLQVAQPFTIGDNKTYSGFWNTPLLPHKSYSIYFQAASRANGETKIDCVRVATK----------------- ----------GAATRKP-------------------------DPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETLSS-TRQEMTVMVNSMDKSYTEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTTVPNS-YYPD---------ENHTM---------------------VSDTSSLVQSHTY--KKRDPA DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQPIE---GETNSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--AHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSIPASQVRSAYYEMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSIVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVEKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLQHQRAVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Taeniopygia_guttata-PTPRM(ENSTGUP_10269) ------------------------------------------------------------------------------AG S-FMLVNTSGRFSGQKAHLLMP-HLKENDTHCIDFHYYVSSKSGA--------------TPGILN-VYVKVNDGPIGNPV WN--TS--ITATWSRAELAISTFWPNFYQVVFEVVTS-GHSGYVAIDEVKVLGHPCTKTPHF-LRLQSVEVNAGQFATFQ CTANGGTDSGDRLWLQ--GIYVRDAPLKDIKVFNARRFVALFS--VVNATKRDAGNYRCMIRTEGGVGVSNYAELIVKEP PVPIAPPQLSSVGATYLWIQLNANSINGDGPIIQREVEYRTSSGSWYDIQPVDSTSYKIGHLDPDTEYEISVLLT---RP GEG-GTGSPGPALKTRTKCADPMRGPRRLEVVEIKSRQITICWEPFGYNVTRCHRYNLTVHYRYQAG-------GQEQVR EEVSWDTESSHPQHTITNLSPYTNVSIKLVLMNPEGRKESQELVVQTDED-VPSAVPLESIQGSTF-EEKIFLQWREPAQ TYGVITLYEI--TYKAVSSFDPEIDLSNQSGRVSKLGNETHYLFFGLYPGTTYSFTIRASTAKGFGPPITNQFTTKIS-A PSMPPYEL-ETPLNQ--TDSTVTVLLKPAQSRGAPVS-VYQIVVEEERPRRT-KK-ATEILKCYPVPIHFQNASLLNSQY YFAAEIPANGLVAAQPFTIGDNKTYSGFWNTPLLPHKSYSIYFQAASRANGETKIDCVRVATK----------------- ----------GAATRKP-------------------------DPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKR --------------------KLAKKRKETLSS-TRQEMTVMVNSMDKSYTEQGTNCDEAFSFMDTHN--LNGRSV---SS PSSFTMKTN-TLSTTVPNS-YYPD---------ETHTM---------------------VSDTSSLVQSHTY--KKRDPV DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQPIE---GETSSDYINGNYID------GYHRPN--HYIATQG------PMQETIYDFWRMVWHENTASIIMVTNLVE VGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRG--AHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQV KSKSPPNAGPLVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTSIPASQVRSAYYEMNKLDPQTNSSQIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQKAVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Takifugu_rubripes-PTPRM(ENSTRUP_12361) --SFTLSHLNASHCLAYCIMNAAG------EKITGDCTFEKPL---AACGYSQGR-DDDLDWEQASTREKPSSDPWVPTD SAFAMVNTSGRFAGQKALLLTP-QLRENDTHCVTFHYYIGGRDSS--------------HPGHLN-VYIKENNSPMGMPV WN--VSGPATRSWVQIELAVSTYWPNFYQIVFEAVTS-GQRGLLAIKDIVVKGHQCMNTPHF-LTIKGVEVNAGQTASFH CTVNGRKKDNFRLWLQKQGIGGREAPMRSTKPWNNRRFIGTFD--VKNTTKGDSGRYRCIIHSEKGVGVSNYGELTIKQP PVPIAPPQLTAVGATYLWIQLNANSINGDGPIIEREVEYRTVSGTMYDLQPVDKTTHKIGHLDPDTEYEISVLLT---RP LEG-GTGAPGPLLRAKTKCAEPMHGPRRLQVVDIQATQVTIRWEPLGYNVTRCHSYNLTVQYRSKVG-------GKEETR EEVCYDTQSRDPQHTIHNLTPFTNLSVKLVLRNPEGVMESTELKVQTDED-VPGAVPLESFQGSAY-EEKIILKWREPAQ TYGIITQYEI--SYKAVSSFDPDLDLSNQSGKVVKLGNETTHVFTGLYPGSTYSFTLRASTAKGYGPAIITQFTTKIS-A PSMPAYDQ-ETSLNQ--TDSTVTVLLKPAQSRGAPVS-AYQVVVEEERPRRA-RG-TAEILRCYPVPIHFQNATLLNSQY YFTAQFPATGIHSPQPFTVGDNKTYNGYWNAPLLPQKSYSIYYQAVSSANGETKIDCVRVATK----------------- ----------GSATHKPD------------------------AVEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLLMKKR --------------------KLAKKRKETLNS-TRQEMTVMVNSMDKSYTEQGTNCDEALSFMDTHNHTLNARSD---SS PSSFSLPKANTLSTSMPTSSYYPD---------ESQNV---------------------CSDTSSLVQSHTHSLRKREAV DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQALE---GEQSSDYINANYVD------GYHRPN--HYIATQG------PMQETVFDFWKMVWQENTAAIVMVTNLVE VGRVKCCKYWPDDTEIYRDVKVTLIETELLSEYVIRTFAVEKRG--AHEIREIRQFHFTGWPDHGVPYHATGLLGFIRRV KSKTMTNAGPMVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTTIPASQLRSVYYDMNRLDPQTNSSPIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSIVMLNDVDPAQL---CPQYWPE NGVHRHGHIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPISKRSFLKLIRQVDKWQEEYDG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLQHQRSVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLSSG----- >Tetraodon_nigroviridis-PTPRM(ENSTNIP_... ----NTSLAAALWCWILIMWPSPRSAAHLQACLTGDCTFEKPL---AACGYSQGR-DDDLDWEQASTREKPSSDPWLPSD SAFMMVNTSGRFAGQKALLLTP-QLKENDTHCVTFHYYIGGRDNS--------------HPGHLN-VYIKENNSPIGMPV WN--ISGPATRSWLQIELAVSTYWPNFYQIVFEAVTS-GQRGLLAIKDIVVKGHQCMNTPHF-LTIKGVEVNAGQTASFH CTVNGRKRDNFRLWLQQQGIGGREAPMRSTKPWNNRRFIGTFD--VKNTTKGDSGRYRCIIHSEKGVGVSNYGELTIKQP PVPIAPPQLTAVGATYLWIQLNANSINGDGPIIEREVEYRTVSGTMYDLQPVDKTTHKIGHLDPDTEYEISVLLT---RP LEG-GTGAPGPPLRAKTKCAEPMHGPRRLEVVDIQSTQVTIRWEPLGYNVTRCHSYNLTVQYRSKVG-------GKEDAR EEMCYDTQSRDPQHTIHNLTPFTNLSVKLVLRNPEGVMESKELEVQTDED-VPGAVPLESFQGSAY-EEKIVLKWREPAQ TYGIITQYEI--SYKAVSSFDPDLDLSNQSGKVVKLGNETTHMFAGLYPGSTYSFTLRASTAKGYGPAIITQFTTKIS-A PSMPAYDQ-ETSLNQ--TDSTVTVLLKPAQSRGAPVS-AYQVVVEEERPRRA-RG-TAEILRCYPVPIHFQNATLLNSQY YFTAQFPAAGIHSPQPFTVGDNKTYNGYWNAPLLPQKSYSIYYQAVSTANGETKIDCVRVATK----------------- ----------GSATHKPD------------------------AVEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLLMKKR --------------------KLAKKRKETLNS-TRQEMTVMPGHPNPSTLQRNR----------------NHQNR---SA P--------------YQERKIVLD---------ESQNM---------------------CSDTSSLVQSHTHSLRKREAV DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQALE---GEQSSDYINANYVD------GYHRPNRLHCYSSSG------PMQETVFDFWRMVWQENTAAIVMVTNLVE VGRVKCCKYWPDDTEIYRDVKVTLIETELLSEYVIRTFAVEKRG--AHEIREIRQFHFTGWPDHGVPYHATGLLGFIRRV KSKTMNNAGPMVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTTIPASQLRSVYYDMNRLDPQTNSSPIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDG---SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSIVMLNDVDPAQL---CPQYWPE NGVHRHGHIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPISKRSFLKLIRQVDKWQEEYDG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLQHQRSVDVFHAVKTLRNNKPNMVDLLDQYKFCYESSSGVFELGVTSKF >Tetraodon_nigroviridis-PTPRM(ENSTNIP_(2) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------------?IRCV KAKTPPTAGPTVVHCS-AGAGRTGCFIVIDIMLD----MADREGVVDIYNCVRELRARRVNMVQTEEQYVFIHDAILEAC LCGDTAVPANQLRSVYYEMNRLDPQTNSSQIKEEFRS---VNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDGE--SSNYINAALMD------SYKATSAFIVTQHPLPNTVKDFWRLVLDYHCTSIVMLNDVDPAQL---CPQYWPE NGVHRLGSLQVEFVSADLEEDVISRIFRIYNTARPQDGFRMVQQFQFLGWPMYRDTPISKRSFLKLVHQVDKWQEEYDG- -GEGRTVVHCL------------------------------------------------------------------- >Gasterosteus_aculeatus-PTPRM(ENSGACP_... ---------------------------------TGECNFEKPL---AACGYNQGR-DDDLDWEQVNTREKPSSEPWMPSG SAFVMVNTSGRFAGQKALLLTP-QLRENDTHCVTFYYYIGGRDNS--------------HPGHLN-VYIKENNSPMGMPV WN--VSAAATRSWGQVELAISTYWPNFYQIVFEAVTS-GQRGLLAIKDVVVQGHQCMNTPHF-LTIKGVEVNAGQTASFH CTVNGRKRDNFHLWLQ--GIGGREAPMKATKPWNNRRFIGTFD--VENTTKGDSGRYRCIVHSDKGVGVSNYGELTIKQP PVPIAPPQLTAVGATYLWIQLNANSINGDGPIVDREVEYRTVSGTMYDLQPVDKTTHKIGHLDPDTEYEISVLLT---RP LEG-GTGAPGPPLRARTRCAEPMHGPQRLEVVDIQSKQVTVRWMPLGYNVTRCYSYNLTVQYRSRVA-------GKEETR EEVCYDTGSRDPQHTIHNLTPFTNLSVKLVLRNPEGVKESTELEVQTDED-VPGSVPLESVQGSAY-EEKIILKWREPAQ TYGIITQFEI--SYKAVSSFDPELDLSNQSGKIVKLGNETAHVFTGLYPGSTYSFTLRASTAKGYGPPVVTQFTTKIS-A PSMPAYEQ-ETSLNQ--TDSTVTVLLKPAQSRGAPVS-AYQVVVEEERPRRA-RG-TAEILRCYPVPIHFQNATLLNSQY YFTAQFPSGGIHSPQPFTVGDNKTYNGYWNAPLLPQKSYSIYYQAVSTANGETKIDCVRVATKAAILVTQLTTPYVRVAP AAGDNQLT--GAATHKPD------------------------AVEPEKQTDHTVKIAGVIAGILLFVIIFLGLVLLMKKR --------------------KLAKKRKETLSS-TRQEMTVMVNSMDKSYTEQGTNCDEALSFMDTHNHTLNTRSELAGSS PSSFTLPKASTLSTSIPTNSYYQDPFVPTAILDESQNM---------------------GSDTSSLVQSHTHSLRKREPV DVPYQTGQLHPAIR---VADLLQHITQMKC--AEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYD---HSR VRLQTLE---GEQSSDYINANYVD------GYHRPN--HYIATQG------PMQETVFDFWRMVWQENTAAIVMVTNLVE VGRVKCCKYWPDDTEIYRDIKVTLIETELLSEYVIRTFAVEKRG--AHEIREIRQFHFTGWPDHGVPYHATGLLGFIRRV KSKTLTNAGPMVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEAC LCGDTTIPASQLRSVYYDMNRLDPQTNSSPIKEEFRT---LNMVTPTLRVEDCSIALLPRNHEKNRCMDVLPPDRCLPFL ITIDGE--SSNYINAALMD------SYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSIVMLNDVDPAQL---CPQYWPE NGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPMSKRSFLKLIRQVDKWQEEYDG- -GEGRTVVHCLNGGGRSGTFCAISIVCEMLQHQRSVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG----- >Homo_sapiens_PTPRK(ENSP_357193) -MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGP---GACDYHQDL-YDDFEWVHVSAQEPHYLPPEMPQG S-YMIVDSSDHDPGEKARLQLP-TMKENDTHCIDFSYLLYSQKGL--------------NPGTLN-ILVRVNKGPLANPI WN--VTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVHNKLWLQ--RRNGEDIPVAQTKNINHRRFAASFR--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES KADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPVPVKSLQGTSF-ENKIFLNWKEPLD PNGIITQYEI--SYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKREAGAMECYQVPVTYQNAMSGGAPY YFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILIVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Mus_musculus-PTPRK(ENSMUSP_20042) --MDVAAAALPAFVALWLLYPWPLLGSALGQFSAGGCTFDDGP---GACDYHQDL-YDDFEWVHVSAQEPHYLPPEMPQG S-YMVVDSSNHDPGEKARLQLP-TMKENDTHCIDFSYLLYSQKGL--------------NPGTLN-ILVRVNKGPLANPI WN--VTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVHNKLWLQ--RRNGEDIPVAQTKNINHRRFAASFR--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES RADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPVPVKSLQGTSF-ENKIFLNWKEPLE PNGIITQYEV--SYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PSLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEQLHPHR--TKREAGAMECYQVPVTYQNALSGGAPY YFAAELPPGNLPEPAPFTVGDNRTYKGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVIVIVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVNAMDRSYADQSTLHAEDPLSLTFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMVWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Oryctolagus_cuniculus-PTPRK(ENSOCUP_1... -METAAAAALPALVALLLLSPWPFLGSAQGQFSAGGCTFDDGP---GACDYHQDL-YDDFEWVHVSAQEPHYLPPEMPQG S-YMIVDSADHDPGEKARLQLP-TMKENDTHCIDFSYLLYSQKGL--------------NPGTLN-ILVRVNKGPLANPI WN--VTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVHNKLWLQ--RRNGEDIPVAQTKNINHRRFAASFR--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES KADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETVIQTDED-VPGPVPVKSLQGTSF-ENKIFLNWKEPLE PNGIITQYEV--SYSSIRSFDPAVLVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKREAGAMECYQIPVTYQSAMSGGAPY YFAAELLPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVVLVVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YSEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Bos_taurus-PTPRK(ENSBTAP_53498) ----TAAAALPTFVALLLLSPWPLLGSAQGQFSAGGCTFDDGP---GACDYHQDL-YDDFEWVHVSAQEPHYLPPEMPQG S-YMIVDSSDHDPGEKARLQLP-TMKENDTHCIDFSYLLYSQKGL--------------NPGTLN-ILVRVNKGPLANPI WN--VTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVHNKLWLQ--RRNGEDIPVAQTKNINHRRFAASFR--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES KADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPVPVNSLQGTSF-ENKIFLNWKEPLD PNGIITQYEV--SYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PTLPDYEGIDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKRETGAMECYQVPVTYQNAMSGGAPY YFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILVVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KFSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGTLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Canis_familiaris-PTPRK(ENSCAFP_1549) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------SEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES KADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPVPVNSLQGTSF-ENKIFLNWKEPLD PNGVITQYEV--SYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKREAGAMECYQVPVTYQSALSGGAPY YFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILIVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KFSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Loxodonta_africana-PTPRK(ENSLAFP_13113) -MDT-AAAALPAFVALLLFSPWPLLGSAQGQFSAGGCTFDDGP---GACDYHQDL-YDDFEWVHVSAQEPHYLPPEMPQG S-YMIVDSSDHDPGEKARLQLP-TMKENDTHCIDFSYLLYSQKGL--------------NPGTLN-ILVRVNKGPLANPI WN--VTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGVRSGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVHNKLWLQ--RRNGEDIPVAQTKNINHRRFAASFR--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFR---------GHNES KADCLDMDPKAPQHVVSHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-CLGPVPVKSLKGTSF-ENKIFLNWKEPLD PNGIITQYEV--SYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKREAGAMECYQVPVTYQNAMSGGAPY YFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFIVLLLVVILIVKK -------------------SKLAKKRKDAMGN-TRQEMTHMVSAMDRSYADQSTLHAEDPLSITFMDQHN-FSPRLP--- ----------------------NDPLVPTAVLDENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRG--YNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPE EGTLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS----- >Gallus_gallus-PTPRK(ENSGALP_23810) -------------------------------------------------------------------------------- ------------------------MKENDTHCIDFSYLLYSKSGA--------------NPGTLN-ILVRVNKGPLANPI WN--VTGSTGKDWLRAELAVSTFWPNEYQVIFEAEVSDGRNGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVNNKLWLQ--RRNGEDIPVAQTKNINHRRFAATFK--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGTWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGQPGPPLITRTKCAEPMRTPKTLKIAEIQARHIAVDWESLGYNITRCHTFNVTICYHYFC---------GRNES KADCLDMDPKAPQHVVDHLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPIPAKSVKGTPF-EDKIFLNWKEPVD PNGIITQYEV--SYSSIRSFDPAVPVAGPPQTVSKLWNSTHHVFSHLHPGTTYQFFLRASTVKGFGPATTINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKRETGAMECYQIPVTYQTALSGGSPY YFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILIVKK RLG----------------SKLAKKRKDAMGT-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDSHN-FSPRY---- ---------------------------------ENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYID------GYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACVVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLGRRG--YNEIREVKQFHFTGWPDHGVPYNATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQHPLPNTVKDFWRLVYDYGCTSLVMLNEVDLAQG---CPQYWPE EGILRYGPIQVECVSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHRDVPGSKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVETPEQYRFCYDVALEYLESS----- >Taeniopygia_guttata-PTPRK(ENSTGUP_12110) -------------------------------------------------------------------------------- ------------------------MKENDTHCIDFSYLLYSKNGG--------------NPGTLN-ILVRVNKGPLANPI WN--VTGSTGKDWLRAELAVSTFWPNEYQVIFEAEVSDGRNGYIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDAVNNKLWLQ--RRNGEDIPVAQTKNINHRRFAATFK--LQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREP PRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGTWTETHAVNAPTYKLWHLDPDTEYEIRVLLT---RP GEG-GTGQPGPPLITRTKCAEPMRTPKTLKIAEIQARHIAVDWESLGYNITRCHTFNVTICYHYFC---------GHNES KADCLDMDPKAPQHVVDRLPPYTNVSLKMILTNPEGRKESEETIIQTDED-VPGPIPAKSVKGTPF-EDKIFLNWKEPVD PNGIITQYEV--SYSSIQSFDPAVPVAGPPQTVSKLWNSTHHIFSHLHPGTTYQFFIRASTVKGFGPATTINVTTNIS-A PTLPDYEGVDASLNE--TATTITVLLRPAQAKGAPIS-AYQIVVEELHPHR--TKRETGAMECYQIPVTYQTALSGGSPY YFAAQLPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAA--------------- ------------ATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-ILVFILLLLVVILIVKK RLG----------------SKLAKKRKDAMGT-TRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDSHN-FSPRY---- ---------------------------------ENHSA----------------------TAESSRLLDVPR--YLCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKDQNRTKNRYGNIIAYD---HSR VILQPVE---DDPSSDYINANYID------GYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACVVMVTNLVE VGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLGRRG--YNEIREVKQFHFTGWPDHGVPYNATGLLSFIRRV KLSNPPSAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ---TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQHPLPNTVKDFWRLVYDYGCTSLVMLNEVDLAQG---CPQYWPE EGILRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHRDVPASKRSFLKLILQVEKWQEECEE- -GEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVETPEQYRFCYDVALEYLESS----- >Danio_rerio-PTPRK(ENSDARP_86940) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------EP PRPIAPPQLLGVGPTYLLIQLNANSIFGDGPIILKEVEYRMTSGSWTETHAVNSPNYKLWHLDPDTEYEIRVLLT---RP GEG-GTGQPGPALITRTKCAEPMRTPKSLKIAETQARFIAVDWESLGYNITRCHTFNVTICYHYHK---------TPNHS KADCLEMDPKAPRHVVGNLPPNTNVSLKMILTNPEGRKESDETLIQTQED-VPGPVPKEFVRSTPS-EDKISLQWKEPLE PNGIITQYEI--SYSSVHSFDPSVPLLRPPLLVSLPWNTSRYNFTLLHPGTTYQFLIRASTSKGFGPPTTLNVTTNISVA PTLEEYDGSEASLNE--TATTITVLLKPAQAKGAPIS-AYQIVVKEINPHR--GRREAGGGECYREPVSYQSAVSSGLPY YFAAEIPPRNLQEPLPFTVGDNKTYHGYWNAPLAPRKDYNIYFQAVSRVEKESKTQCLKLAFKGA--------------- -------------TEEPE-----------------------VIPDPAKQTDQVVKIAGISAA-VLVFILLVLVAILLLKK -------------------RKLAKKRKDAIGN-TRQEMTHMVNSMDRSYADQSTLHAEEPMTVTFMDSHN-FSNR----- --------------------------------YENHTAAA-------------------AAAENSRLLDIPR--YHCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDAAKKEQNRTKNRYGNIIAYD---HSR VILQPME---DDPSSDYINANYID------GYQRPS--HYIATQG------PVHETVYDFWRMIWQEQSACIVMVTNLVE VGRVKCYKYWPDDAEVYGDFKVTFVEVEPLAEYVVRTFTLERRG--FNEVREVKQFHFTGWPDHGVPYHATGLLSFIRRV KMSNPPTAGPIVVHCS-AGAGRTGCYIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAYYDMIRIDSQSNSSHLKDEFQ---TLNSVTPQPQPEDCSIALLPRNHDKNRFMDNLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQHPLPNTVKDFWRLVYDYGCTSIVMLNEIDLAQG---CPQYWPE EGMLRYGPVQVDCISCSMDCDVISRLFRICNLTRPQEGYLMVRQFQYLGWAGHREVPASKRSFLKLILQVDKWQEECEE- -GDGRTIIHCLNGGGRSGMFCAISIVCEMIKRQNVVDVFHAVKSLRNSKPNMVDSPEQYRFCYDLALEFIETS----- >Oryzias_latipes-PTPRK(ENSORLP_14115) QRPTVARACPEVVAMGTDDPLKDLLACWLSQSFAGSCTFDEGF---SQCDYQQDS-YDDFDWTHINTQEVPYISPDLPKG S-YMYVDVSQHDVGEKARFQLP-VMKENDTHCIDFNYLLTSTDGS--------------SPGTLN-VLVKVNKGPLANPI WN--VTTYTGKDWLKAELAVSTFWPNEYQVIFEAEVSDSKTGFIAIDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDTSSNKLWLQ--RRNGEDIPVAQTKTINHRRFAASFH--LKEVTGQDQDLYRCVTQSERGSGVSNFAGLIVREP PHPIAPPQLLGVGPTYLLIQLNANSIFGDGPIILKEVEYRMTSGSWTETHAVNSPNYKLWHLDPDTEYEIRVLLT---RP GEG-GTGKPGPPLITRTKCAEPMRTPKRLKIAETRSRLIAVDWESLGYNITRCHTFNVTICYHYMT---------ANNRS KADCLDMDPKAPRHLVGNLPPYTNVSLKMILTNPEGRKESDETVIQTDED-VPGPVPAQSLKATPS-EETINLHWKEPVE PNGVIIQYEI--SYSAIRSFDPSVPLQRPGLTVSLPSNITHHTFSQLHPGVMYLFSIRASTSKGFGPAATLNVTTNIS-A PTIDEYDMTEAFLNE--TATTITVLLKPAQAKGAPIS-AYQIVVEEINHQR--ERRHAS-SDCYKVPVSYHSASSSGSPY YYAAQLSPSNLPEPIPFTVGDNRTYQGFWNPPLAPRKNYNIYLQAVSSTERETKTQCLRLAAKYA--------------- -------------SEEPE-----------------------VIPDPSKQTDRVVKIAGISAG-VLVFILLVLVAILLVKK -------------------RKLAKKRKDVIGT-TRQEMTHMVNAMDRSYADQSTLHGEDPMAVTFMDSHN-YGNR----- --------------------------------YENHSG---------------------SAAENSRLLDVPR--YHCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESFFEGQSASWDVAKKEQNRTKNRYGNIIAYD---HSR VILQPTE---DDPSSDYINANYID------GYQRPS--HYIATQG------PVHETVYDFWRMVWQEQSACIVMVTNLVE VGRVKCYKYWPDDAELYGDFKVTFVEVEPLAEYVVRTFTLERRG--FNEVREVKQFHFTGWPDHGVPYHATGLLSFIRRV KMSNPPTAGPIVVHCS-AGAGRTGCFIVIDIMLD----MAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEAC LCGETAIPVCEFKAAFYELIRIDSQTNSSHLKDEFQ---TLNSVTPQPQPEDCSIAMLPRNQDKNRFMDGLPPDRCLPFL ITIDGE--SSNYINAALMD------NYRQPAAFIVTQHPLPNTVKDFWRLVYDYGCTSLVMLNEIDLTQG---CSQYWSE EGVFRYGPVQVECMSSLKDCDVISRLFRVCNLTRPQEGYLMVRQFQYLGWAGHREVPTSKRSFLKLILQVDQWQREGEE- -GEGRTIVHCLNGGGRSGVFCACSIVCEMAKRQSVVDVFHAVKTLRNSKPNMVDTPEQYRFCYDLALEFIESS----- >Takifugu_rubripes-PTPRK(ENSTRUP_45855) ---------------------------------AGSCTFNEGF---SKCDYQQDP-YNDFDWTHINTKEVPYVSPDLPQG S-YMYVDVSQYTVGEKARFQLP-VMKENDTHCIDFNYFLTSPDGS--------------SPGTLN-VLVKVNKGPLANPI WN--VTTFTGKEWLKAELAVSTFWPNEYQVIFEASVLDSKVGFIAVDDIQVLSYPCDKSPHF-LRLGDVEVNAGQNATFQ CIATGRDTTSNKLWLQ--RRNGEDIPVAHTKTINHRRFAASFN--LKEVTSQDQDLYRCVTQSERGSGVSNFAGLIVREP PHPIAPPQLLGVGPTYLLIQLNANSIFGDGPIILKEVEYRMTSGTWTETHAVNSPNYKLWHLDPDTEYEIRVLLT---RP GEG-GTGKSGPPLITRTKCAEPMRTPKRLKIAETRSRLIAVDWESLGYNITRCHTFNVTICYHYMT---------ANNHS KADCLDMDPKAPRHLVGNLPPYTNVSLKMILTNPEGRKESDETIIQTDED-VPGAVPSQSLRATPF-EDRILLYWKEPSE PNGIIIQYEI--SYSGLRSFDPSVPLQRPGLTASLPSNASHHLFSQLHPGVTYQLSIRASTSKGFGPATTLNVTTNIS-A PTIEEYDGSEAFLNE--TATTITVLLKPAQAKGAPIS-AYQIVVEIVIPQR--TRRQAS-SDCYEVPVSYHSASSRGSPY YYAAQLSPSNLPEPLPFTVGDNKTYQGFWNPPLALRKNYNIYLQAVSSTEKETKTQCLRLATKAMLT------------- -----------GATEEPE-----------------------VIPDPAKQTDRVVKIAGISAG-VLVFILLVLVAILLVKK -------------------RKLAKKRKDVIRT-TGQEMTHMVNSMDRSYADQSTLHGDDPMAVTFMDSHN-YNNRLP--- ----------------------NDPLVPTAVLDENHTG---------------------SAAENSRLLDVPR--YHCEGT ESPYQTGQLHPAIR---VADLLQHINLMKT--SDSYGFKEEYESLFEGQSASWDVAKKEQNRTKNRYGNIIAYD---HSR VILQPIE---DDPSSDYINANYIDIWLYRDGYQRPS--HYIATQG------PVHETVYDFWRMVWQEQSACIVMVTNLVE VGRVKCFKYWPDDAELYGDFKVTFVEVEPLAEYVVRTFTLERRG--FNEVREVKQFHFTGWPDHGVPYHATGLLSFIRRV KISNPPSAGPIVVHCS-AGAGRTGCFIVIDIMLKKSFTHSHPQSSLQFILCVSSEPKLQSSHQQTQEQYIFIHDAILEAC LCGETAIPVCEFKAAFYELIRIDSQTNSSHLKDEFQ---TLNSVTPQPQPEDCSIALLPRNQDKNRFMDGLPPDRCLPFL ITIDGE--SSNYINAALMD------SYRQPAAFIVTQHPLPNTVKDFWRLVYDYGCTSLVMLNEIDLAQG---CPQYWPE EGMLRYGPVQVECMSCSMDCDIISRLFRVCNLTRPQEGYLMVRQFQYLGWAGHRDVPASKRSFLKLILQVDQWQREGEE- -GEGRTIVHCLNGGGRSGVFCASSIVCEMSKRQSVVDVFHAVKTLRNSKPNMVDTPEQYRFCYDLALEFIESS----- >Takifugu_rubripes-PTPRK(ENSTRUP_6014) -------------------------------------------------------------------------------- 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