>Homo_sapiens-LAPTM4A(ENSP_175091) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMSFKRNRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNVPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Macaca_mulatta-LAPTM4A(ENSMMUP_2109) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNVPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gorilla_gorilla-LAPTM4A(ENSGGOP_21414) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMSFKRNRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNVPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Mus_musculus-LAPTM4A(ENSMUSP_20909) ------------------------------------------------------------MWQKAEGEIPSRRPARAAPG AQSAGAQELARARAEGGPEDASFGCGHRRRVVWVEPLGRKLLSGAWARTRPARFRMVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFVVFIIFK--AYLINCVWNCYKYIN-------NRNVPEIAVYPAFETPP---- ------------QYVLPTYEMAVKIPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Rattus_norvegicus-LAPTM4A(ENSRNOP_9665) ------------------------------------------------------------MYQKAEGESPSRGPARAAPS AQSAGAQELAGARAEGGPEDASFGFGQRRRVVWVEPLGRKLLSGAWARARPTRFPMVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFVVFIIFK--AYLINCVWNCYKYIN-------NRNVPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKIPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryctolagus_cuniculus-LAPTM4A(ENSOCUP... -------------------------------------------------------------------------------G AQCAGAEELG-ARAGGGLEDASFGLGRRESTVRAQPLRGKLWSVTGPAARPASLPMVSMTFKRSRSDRFYSTRCCGCCHV RTGTIVLGTWYMVVNLLMAILLIVEVTHPNLMPAVNN----------------------IQYEVIGNYYSSERMADNVCV LFAVSVLTFIISSVLVYGAIFYQGGWL------------------IPFFCYRLFDFVLSCLVAVSSLTYLPRIKEYLDQL ---PDFPYKDDLLSLDSSCLLFIVLMFFVVFIIFK--AYLIYCVWNCYKYIN-------NRNLPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYLPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Bos_taurus-LAPTM4A(ENSBTAP_27837) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNMPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris-LAPTM4A(ENSCAFP_5704) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNMPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Equus_caballus-LAPTM4A(ENSECAP_14248) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMTFKRSRSDRFYSNRCCGCCHV RTETIILGTWYMVVNLLMAILLTVEVTHPNSMPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSSLLFIVLTFFALFIIFK--AYLINCVWNCYKYIN-------NRNMPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Myotis_lucifugus-LAPTM4A(ENSMLUP_1466) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------VVNLLMAILLTVEVTHPNSMPSVN-----------------------IQYEVIGNYYSSERMTDNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLAFFVLFIIFK--AYLINCVWNCYKYIN-------NRNTPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Pteropus_vampyrus-LAPTM4A(ENSPVAP_2745) -------------------------------------------------------------------------------- -------------------------------------------------------MVSMTFKRSRSDRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMAILLTVEVTHPNSVPAVN-----------------------IQYEVIGNYYSSERMADNACV LFAVSVLMFIISSMLVYGAISYQVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIN-------NRNTPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus-LAPTM4A(ENSO... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------TVFQVVNLLVGILLTVEVTHPNTVPAVN-----------------------IQYEVIGNYYSSERMAENACV LFAVSLLMFTISAMMVYGAIAHRVGWL------------------IPFFCYRLFDFVLSCLVAISSLTYLPRIKDYLDQL ---PDFPYKDDLLALDSSCLLFIVLVFFALFIIFK--AYLINCVWNCYKYIS-------NRNLPEIAVYPAFEAPP---- ------------QYILPTYEMAMKMPE---------KDPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus-LAPTM4A(ENSGALP_36077) -------------------------------------------------------------------------------- -------------------------------------------------------AASMTFKRSR-DRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMGILLTVEVTHPNVVPTVN-----------------------IQYEVIGNYYASERMAENACV LFAISLLMFTISAMMVYGAIAHRVGWL------------------IPFFCYQLFDFVVSCLVAISSLTYLPRIKDYLDQL ---PDFPYKDDLLSLDSSCLLFIVLVFFALFIILK--AYLINCVWNCYKYIS-------NRNLPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Taeniopygia_guttata-LAPTM4A(ENSTGUP_1... -------------------------------------------------------------------------------- --------------------------------------------------------AAMTFKRSR-DRFYSTRCCGCCHV RTGTIILGTWYMVVNLLMGILLTVEVTHPNMVPSVD-----------------------IQYEVIGNYYASERMAENACV LFAISLLMFTISAMMVYGAIAHRVGWL------------------IPFFCYQLFDFVLSCLVAISSLTYLPRIKDYLDQL ---PDFPYKDDLLSLDSSCLLFIVLVFFVLFIILK--AYLINCVWNCYKYII-------NRSFPEIAVYPAFEAPP---- ------------QYVLPTYEMAVKMPE---------KEPPPPYIPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio-LAPTM4A(ENSDARP_6123) -------------------------------------------------------------------------------- -------------------------------------------------MFLQSTENDMR-FKPSRDRLYSARCCGCCHV RTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTVD-----------------------LQYEVIEHYFASDRMSENACV GFAISLLMLTISAMMVYGAITNRDGWL------------------IPFFCYQLFDFALSCLVAISSLTYLPRIKDYLDQL ---PDFPYKDNLLSLDSSCLLLFVLIFFAILIVLK--AYLINCVWNCYKYIN-------NRNTPEIAVYPAFETPP---- ------------QYILPTYEMAMTMPA---------KEPPPPYMPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryzias_latipes-LAPTM4A(ENSORLP_15729) -------------------------------------------------------------------------------- -------------------------------------------------MFLPTLVEDMHHFKPSRDRLYTTRCCGCCHV RTGTIILGTWYIVVNLLMGILLTVAVTHPENVPTID-----------------------LQYEVIDHYFASDRMSENACV GFAISLLMLTISAMMVYGAITHRDGWL------------------IPFFCYQLFDFALSCLVAISSLTYLPRIRDYLDQL ---PDFPYKDNLLSMNSSCLLLFVLVFFAFLIILK--AYLINCVWNCYKYIN-------NRNMPEIAVYPAFETPP---- ------------QYILPTYEMAMKMPE---------KDPPPPYMPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes-LAPTM4A(ENSTRUP_46460) -------------------------------------------------------------------------------- -------------------------------------------------------VEDMHHFKPSRDRLYTTRCCGCCHV RTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTID-----------------------LQYEVIDHYFASDRMSENACV GFAISLLMLTISAMMVYGAITHRDGWL------------------IPFFCYQLFDFALCCLVAISSLTYLPRIKDYLDQL ---PDFPYKDNLLSMDSSCLLLFVLVFFAFLIILK--AYLINCVWNCYKYIN-------NRNMPEVAMYPAFETPP---- ------------QYILPTYEMAMKMPE---------KEPPPPYMPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Tetraodon_nigroviridis-LAPTM4A(ENSTNI... -------------------------------------------------------------------------------- -------------------------------------------------MFLPTLVEDMNHFKPSRNRLYTTRCCGCCHV RTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTID-----------------------LQYEVIDHYFASDRMSENACV GFAISLLMLTISAMMVYGAITHRDGWL------------------IPFFCYQLFDFALCCLVAISSFTYLPRIKDYLDQL VLQPDFPYKDNLLSMDSSCLLLFVLIFFAFLIILK--AYLINCVWNCYKYIN-------NRNMPEVAVYPAFETPP---- ------------QYILPTYEMAMKMPE---------KEPPPPYMPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus-LAPTM4A(ENSGAC... -------------------------------------------------------------------------------- -------------------------------------------------MFLPTLVEDMHHFKPSRERLYTTRCCGCCHV RTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTID-----------------------LQYEVIDHYFASDRMSENACV GFAISLLMLTISAMMVYGAITHRDGWL------------------IPFFCYQLFDFALSCLVAISSLTYLPRIKDYLDQL ---PDFPYKDNLLSLDSSCLLLFVLVFFAFLLILK--SYLINCVWNCYKYIN-------NRNMPEIAVYPAFETPP---- ------------QYILPTYEMAMKMPE---------KEAPPPYMPA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Hydra_magnipapillata-LAPTM4A(XP_00217... -------------------------------------------------------------------------------- ----------------------------------------------------MKSEENIRIQSISDERMKPTRCCLCMDV RLATVLIGLFCMAVNAAGFIASTTVMLKNKEKLGEWK-------------------------YFSNVKQASTSHAVDQLI GLSVTSICFVIIIALVYGAIKRKSNYI------------------LPFFCLQVFDATVTLMVAATMISYAPQVKYFIENH P--EVYMSADCISHMSVEKFRYFLVLFWLVMLTAK--YFMMTVVWSCYKYCKSFEERQSLVQLPQMLYHGNMDTVTN--- ---------------LPSYEDVVKIAP------------PPAYSS----------------------------------- -------------------------------------------------------------------------------- ------------------------ >Drosophila_melanogaster-LAPTM4A(FBpp0... -------------------------------------------------------------------------------- ----------------------------------MFRIHLKMGPQRNQLHSNNNNGAAGSSSSTGNRHLKEFTCCFGLHV HTATLMIGLWHLFLNILALSVLAVIWRNPEMMDELEGGTHDYTVDLSAPALPTPLSKVEPPYAYRDHSLNYRKRYQNFDM GGLVCTCMIAITLMMIYGTIKGKPSHL------------------LPFFCLQLFDFAITTLTAAGYLCYLQAIHSIIAES H---RLPWREKLLELPPEELVVVVLVVFICIVFLK--AYCIGIVWRCYKYLT-------LRQQHVRTLFPFLEPPTGVHS VGGTFGAEERSYSTLLPNYDEAIAQYL--------KQAPPPSYQVAMSNYEEGEDAAVGGAEVNPSVAPLFVALGAATTA NVASNTDDNMDNNNDQPNNNNTMHVNANTPPMRRSDAAVNANVDEEADDLEVIDAGVDVIGGIPPPPPYNDVADAQVQVP SQSPLHRQPNIPGQVFGGRDESQA >Ciona_savignyi-LAPTM4A(ENSCSAVP_614) -------------------------------------------------------------------------------- ----------------------------------------------------------------MTRNSVSTSCCFCLHV KTGTFMLSVLSGVSGLFALVVCSLALSGAVNFESYDVGT--------------------SKVFEQLYDHASTYQRSALWI GLGNGIFLTLISSLAVFGLIKKRPGFL------------------LPFFICQLFNFLCTIVYIGSVMFYWPSIKYNL--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ciona_intestinalis-LAPTM4A(ENSCINP_10... -------------------------------------------------------------------------------- ----------------------------------------------------------------MTRNTPSSTCCFCCHV KTGTFMLAVLTGVAGLITLVFCTLALSGSIEVQ-YDLGS--------------------AKMFNDLYENES-YRHSALWI GVGNGVFITLISGLAVFGLIKNRSGFL------------------LPFFICQLFNFLCTIVYIGSVMFYWPSIKANLLRC P-QMPQEWKDWLMSVDERWLACIVFTILFIIMVIK--SYLIAVVYRCYKHITTQQVILRQRQDPEIMCVSNNKEKSCP-- ------------IYKPPKYEDIQKVPLFDDMEEIDTKPAPPPYAA----------------------------------- -------------------------------------------------------------------------------- ------------------------ >Strongylocentrotus_purpuratus-LAPTM4A... -------------------------------------------------------------------------------- ------------------------------------------------------------------------------MG QMFAMLLIASMIMRGGDNAMNIDLDEQDP---------------------------------PQTPLSLNSQHDASDYCV GLVIVFCFLLITTMMMKGIIQYRSGYI------------------LPFFCLQLFDFFITFLTCIGVMSYYP---DFDYED S--PKFPYNQASTKANMGVTESEMPT------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Homo_sapiens-LAPTM4B(ENSP_367995) MELHERPDERRKARTSTQGRLGDWRRVHADGFTHRVWSSSSWLEPAMTSRTRVTWPSPPRPLPVPAAAAVAFGAKGTDPA EARSSRGIEEAGPRAHGRAGREPERRRSRQQRRGGLQARRSTLLKTCARARATAPG--AMKMVAPWTRFYSNSCCLCCHV RTGTILLGVWYLIINAVVLLILLSALADPDQ----YN----------------------FSSSELGGDFEF-MDDANMCI AIAISLLMILICAMATYGAYKQRAAWI------------------IPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQL P--PNFPYRDDVMSVNPTCLVLIILLFISIILTFK--GYLISCVWNCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDA-TVNG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Macaca_mulatta-LAPTM4B(ENSMMUP_11704) MQLHEWPDEKGKAGTSTDGRLGDRPRVHADGFIHPGLAAPSWLEPAMTSR-RVTWPSPPRPLP----AATAFGAQGPDAA DARRSRGIEEAR-RAHGREGREPERRRSRQQRRGGPQARRST-LKTWARARATAPG--AMKMVAPWTRFYSNSCCLCCHV RTGTILLGVWYLIINAVVLLILLSALADPDQ----YH----------------------FSSSELGGDFEF-MDDANMCI AIAISLLMILICAMATYGAYKQRAAWI------------------IPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQL P--PNFPYRDDVMSVNPTCLVLIILLFISIILTFK--GYLISCVWNCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDA-TVNG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gorilla_gorilla-LAPTM4B(ENSGGOP_535) MELHERPDERRKARTSTQGRLGDWRRVHADGFTHPGRSSSSWLEPAMTSRTRVTWPSPPRPFPVPAAAAVAFGAKGTDPG EARSSRGIEEAGPRAHGRAGREPERRRSRQLR-GGLQARRSTLLKICARARATAPG--AMKMVAPWTRFYSNSCCLCCHV RTGTILLGVWYLIINAVVLLILLSALADPDQ----YH----------------------FSSSELGGDFEF-MDDA---- ---------------------QRAAWI------------------IPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQL -------------------------------------GYLISCVWNCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDA-TVNG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Mus_musculus-LAPTM4B(ENSMUSP_22867) -------------------------------------------------------------------------------- -----------------------------------------------------------MKMVAPWTRFYSHSCCLCCHV RTGTILLGVWYLIINAVVLLILLSALADPNQ----YH----------------------FSGSELGGEFEF-MDDANMCI AIAISLLMILICAMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQL P--PSFPYRDDIMSVNPTCLVLIILLFIGILLTLK--GYLISCVWSCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDATAVPS-------TAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Rattus_norvegicus-LAPTM4B(ENSRNOP_8969) -------------------------------------------------------------------------------- -----------------------------------------------------------MKMVAPWTRFYSHSCCLCCHV RTGTILLGIWYLIINAVVLLILLSALADPDQ----YH----------------------FSGSELGGEFEF-MDDANMCI AIAISLLMILICAMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQL P--PSFPYRDDIMSVNPTCLVLVILLFIGIILTFK--GYLISCVWSCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDATAVTG-------TAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryctolagus_cuniculus-LAPTM4B(ENSOCUP... -------------------------------------------------------------------------------- ------------------------------------------------------------RMVAPWTRFYSNSCCLCCHV RTGTILLGVWYLIINAVVLLILLSALADPDQ----YH----------------------FSGSELGGDIEF-MDDANMCI AIAISLLMILICAMATYGAYKQHAAWL------------------IPFFCYQIFDFALNTLVAVTVLVYPNSIQEYIRQL P--PNFPYREDIMAVNPTCLVLIILLFISIILTFK--GYLISCVWNCYRYIN-------SRNASDVLVYVTSNDTT---- -------------VLLPPYDDA-AVNG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Bos_taurus-LAPTM4B(ENSBTAP_22559) -----------------------------------------PREPRPAPLPALVPPPFSAALGALAPAEVPTASS--SRG EARGPGPVVGGRGPGRGSEGSR---GERGRRQPRGAQDRRPKLLRTWAQSRATAPAARAMKMVAPWTRFYSNSCCLCCHV RTGTILLGVWYLILNAVVLLILLSALADPDH----YH----------------------FSSSELGGDFEF-MDDANMCI AIAISVLMILICAMATYGAYKQRAAWI------------------IPFFCYQIFDFALNTLVAVTVLVYPNSIQEYIRQL P--PDFPYKDDIMSVNPTCLVLIILLFISIILAFK--GYLISCVWNCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDA-TVNS-------ATKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris-LAPTM4B(ENSCAFP_679) -------------------------------WEEESWRPLEPAVTSLAPARVTWPPPPMTLTKAPAPPPAAFAAGGLAAA AARRAGLRRGAQSTVRVGEGAQRAAGEPATAARPAPSDAPDTPANLGARSRHGALAAGAMKSVAPWRRFYSSSCCLCCHV RTGAILLGVWYLIINAVVLLILLSALADPDQ----YH----------------------FSSSELGGDFEF-MDDANMCI AIAISLLMILICAMATYGAYKQRAAWI------------------IPFFCYQIFDFALNTLVAVTVLVYPNSIQEYIRQL P--PNFPYRDDIMSVNPTCLVLIILLFISIILTFK--GYLISCVWNCYRYIN-------GRNSSDVLVYVTSNDTT---- -------------VLLPPYDDA-TVNG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Equus_caballus-LAPTM4B(ENSECAP_17633) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------VINAVVLLILLSALADPDQ----YH----------------------FSSSELGGDFEF-MDDANMCI AIAISLLMILICAMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAVTVLVYPNSIQEYIRQL P--PNFPYKEDIMSVNPTCLVLIILLFISIILAFK--GYLISCVWNCYRYIN-------GRNASDVLVYVTSNDTT---- -------------VLLPPYDDA-AVNG-------TAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Myotis_lucifugus-LAPTM4B(ENSMLUP_3296) ---------------------------------------------------RVTWSGPPRLLPLPSPAAS---AQGPAAA VARSFRRGAQPGLGVSQREGREPERPRGRQQPRAAAGATPRVPQTAAR-----APALGAMKMVAPWTRFYSNSCCLCCHV RTGTILLGVSYLVINAVVLLILLSSLADPGQ----RQ----------------------FSSSELGGDLEF-MDDANMCI AIAISLLMILICAMATYGAYKRRAAWI------------------VPFFCYQIFDFALSALVAITVLVYPNSIQEYIRQL P--PNFPYKEDAMSVNSTCLVLVVLLFISILLAFK--GYLISCVWNCYRYIN-------GRNNSDVLVYVTSNDST---- -------------VLLPPYDDA-TVTG-------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Monodelphis_domestica-LAPTM4B(ENSMODP... -------------------------------------------------------------------------------- -----------------------------------------------------------MKMNAPWTRFYSNSCCLCCHV RTGTILLGIWNLIINAVVLLILLSAMADPDQ----YH----------------------LSNSELGGDFEF-MDDANMCI ATAISLLMILICAMATYGAYKQHAAWI------------------IPFFCYQIFDFALNSLVAISVLVYPNSIQEYIRQL P--PNFPYKEDLMSVNPTCLVLIILLFISIVLAFK--GYLISCVWNCYRYIN-------GRNSSDILVYITTNDTT---- -------------VLLPPYDDTTTASTA------TGKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus-LAPTM4B(ENSO... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --GYQLVGVWNLILNAVVLLILLSALADPDR----FH----------------------LSSAELGGDFEF-MDDANICI ATAISLLMILICAMATYGAYKQHAAWI------------------VPFFCYQIFDFALNTLVAISVLVYPNTIQEYIRQL P--ANFPYKEDIMSVNATCLVLIILLFISIVLAFK--GYLISCVWNCYRYVS-------GRNTSDVLVYITTNDTT---- -------------VLLPPYNDTANG---------AAKEPPPPYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus-LAPTM4B(ENSGALP_25740) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MCI ATAISLLMILICAMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAISVLVYPSTIQDYLRQL P--SNFPYKEEIMSVNPTCLVVIILLFISIILAFK--GYLISCVWNCYRYIN-------GRNNSEVLVYITTNDTA---- -------------ISSLPV------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Taeniopygia_guttata-LAPTM4B(ENSTGUP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MCI ATAISLLMILICAMATYGAYKQHAVWI------------------IPFFCYQIFDFALNTLVAISVLVYPSTIQDYLRQL P--SNFPYKEEIMSVNPTCLVVIILLFISIILAFK--GYLISCVWNCYRYIS-------GRNNSDVLVYITTNDTA---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio-LAPTM4B(ENSDARP_52079) -------------------------------------------------------------------------------- -------------------------------------------------------------MISPWDRWYTTSCCLCCHV RTGTIILGIWYMLINAVVLLILLSALNDPVQY--HYH----------------------LTSSELGTDLDV-MDDANMCI AAAISLLMILICGMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAISVVVYPNTIQDYLQQL P--GTFPYKEDLMSTNNMCLVLAVLLFVGCILAFK--AYLIACVWNCYRYVS-------GRSTTEVLVYVTTNDTT---- -------------VLLPPYEEAIAIPP---------KDPPPQYVSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryzias_latipes-LAPTM4B(ENSORLP_16528) -------------------------------------------------------------------------------- ------------------------------------------------------LLTAAFKMISPWDRWYSTSCCLCCHV RTGTIILGIWYMLINAVVLLILLSALNDPVQY--RYH----------------------LTSSELGTDIDV-MDDANICI ATAISLLMILICGMATYGAFKQHAAWI------------------IPFFCYQIFDFALNTLVAISVVVYPNTVQDYLHQL P--GTFPYKEDIMSTNNMCLVLAVLLFIGGILCFK--AYMIGCVWNCYRYVS-------GRGTTEVLVYVTTNDNTP--- ------------KVLLPPYEEAVAIPP---------KDTPPQYNQA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryzias_latipes-LAPTM4B(ENSORLP_3623) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------LINAVVLLILLTALSDPEQ----YH----------------------LTSAELANDLDV-MDDANMCI ASAISLLMILICGMATYGAYKLRAAWI------------------IPFFCYQIFDFALNTLVAVSIVVYPNTIQDYLQQL P--DNFPYKEEVSALSSVWLVLIVLLFIGCILGFKNQAYLIACVWNCYRYVS-------GRGSSELLLYVTTNDTT---- -------------VLLPPYDDNMSVPP---------KRVPAPCTSA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes-LAPTM4B(ENSTRUP_26828) -------------------------------------------------------------------------------- -----------------------------------------------------AVTKGKDKMISPWDRWFSTSCCLCCHV RTGTIILGVWYMLINAVVLLILLTALSDPDQ----YH----------------------LTSAELANDLDV-MDDANMCI ASAISLLMILICGMATYGAYKLRSAWI------------------IPFFCYQIFDFALNTLVAVSIVVYPNTIQDYLQQL P--ENFPYKDEIAALSNVCLVLIVLLFIGCILAFK--AYLIACVWNCYRYVT-------SRGSSEVLLYVTTNDTT---- -------------VLLPPYDDGVGVPV---------KQGPPPYNTA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes-LAPTM4B(ENSTRUP_38188) -------------------------------------------------------------------------------- -----------------------------------------------------------ARMISPWDRWYSTSCCLCCHV RTGTIILGIWYMLINAVVLLILLSALNDPVQY--RYH----------------------LTSSELGTDVDV-MDDANICI ATAISLLMILICGMATYGAYKQHAAWI------------------IPFFCYQIFDFVLNTLVAISVVVYPNTVQDYLQQL P--GTFPYKEDIMSTNNMCLVFAVLIFIGCILSFK--AYLIGCVWNCYRYVS-------GRGTTEVLVYVTTNDTT---- -------------VLLPPYEEAIAIPP---------KEPPPQYMEA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Tetraodon_nigroviridis-LAPTM4B(ENSTNI... -------------------------------------------------------------------------------- -----------------------------------------------------------TRMISPWDRWYSTSCCLCCHV RTGTIILGIWYMLINAVVLLILLSALNDPVQY--RYH----------------------LTSSELGTDVDV-MDDANICI ATAISLLMILICGMATYGAYKQHAAWI------------------IPFFCYQIFDFVLNTLVAISVVVYPNTVQDYLQQL P--GTFPYKEDIMSTNNMCLVFAVLIFIGCILSFK--AYLIGCVWNCYRYVS-------GRGSTEVLVYVTTNDTT---- -------------VLLPPYEEAVATPP---------KEPPPRYMEA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Tetraodon_nigroviridis-LAPTM4B(ENSTNI(2) -------------------------------------------------------------------------------- -----------------------------------------------------AVTDGNNKMISPWHRWLSTSCCLCCHV RTGTIILGVWYMLINTVVLLILLTALSDPDQ----YH----------------------LTSAELANDLDV-MDDANMCI ASAISLLMILICGMATYGAYKLRAAWI------------------IPFFCYQIFDFALNTLVAVSIVVYPNTIQDYLQQL P--NNFPYKDEIAALSNICLVLLVLLFISCILGFK--AYLITCVWNCYRYVT-------SRGSSEVLLYVTTNDTT---- -------------VLLPPYDDGVGAPG---------KQGPPPYNTA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus-LAPTM4B(ENSGAC... -------------------------------------------------------------------------------- -----------------------------------------------------------FRMISPWDRWYSTSCCLCCHV RTGTIILGIWYMLINAVVLLILLSALNDPVQY--RYH----------------------LTSSELGTDIDV-MDDANICI ATAISLLMILICGMATYGAYKQHAAWI------------------IPFFCYQIFDFALNTLVAISVVVYPNTVQDYLQQL P--GTFPYKEDIMSTNNVCLIFAVLLFIGCILSFK--AYLIGCVWNCYRYVS-------GRGTTEVLVYVTTNDTA---- -------------VLLPPYEEALAVPP---------KDPPPQYMEA---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Homo_sapiens-LAPTM5(ENSP_397380) -------------------------------------------------------------------------------- ---------------------------------------------------------------MDPRLSTVRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLR---IADLISSFLLITMLFIISLSLLIGVVKNREKYLLP FLSLQIMDYLLCLLTLLGSYIELPAYLKLASRS------RASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEDMPHNQFIKMMIIFSIAFITVLIFK--VYMFKCVWRCYRLIK-------CMNSVEE-----KRNSKM--- ----------LQKVVLPSYEEALSPAGP-VSCSQLGQRFRLSHSSGLSIIQPNNAWFISISSDTCLDDWPF--------- -------------------------------------------------------------------------------- ------------------------ >Macaca_mulatta-LAPTM5(ENSMMUP_11458) -------------------------------------------------------------------------------- ---------------------------------------------------------------MDPRLSTVRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSIEVAHGKASCKLSKMGYLR---IADLISSFMLIAMLFVISLSLLIGVVKNREKYLLP FLSLQIMDYLLCLLTLLGSYIELPAYLKLASRS------RASPSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLTSQEDMPYNQAVPG--IFWTGCLTWAFFQ--VYMFKCVWRCYRFIK-------CLNSIEE-----RSNSKM--- ----------FQKVVLPSYEEALSLP----SKTPEGDPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gorilla_gorilla-LAPTM5(ENSGGOP_16614) -------------------------------------------------------------------------------- -------------------------------------------------------------STMDPRLSTVRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLR---IADLISSFLLITMLFIISLSLLIGVVKNREKYLLP FLSLQIMDYLLCLLTLLGSYIELPAYLKLASRS------RASPSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEDMPHNQFIKMMIIFSIAFITVLIFK--VYMFKCVWRCYKFIK-------CMNSVEE-----KRNSKM--- ----------LQKVVLPSYEEALSLP----SKTPEGGPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Mus_musculus-LAPTM5(ENSMUSP_118415) -------------------------------------------------------------------------------- ---------------------------------------------------------------MASRAAPVRQTCCCFNI RVATIALAIYHIVMSVLLFIEHVVEVARGKVSCRFFKMPYLR---MADLLSSFLLIGVLFIISISLLFGVVKNREKYLIP FLSLQIMDFLLCLLTLLGSYIELPAYLKLARPR-------PGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGVPHSQFINMMLIFSVAFITVLILK--VYMFKCVYTCYKFLK-------HMNSAME-----DSSSKM--- ----------FLKVALPSYEEALSLP----PKTPEGDPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Rattus_norvegicus-LAPTM5(ENSRNOP_15198) -------------------------------------------------------------------------------- ----------------------------------------------------------RGPCTMASRAVPVRQTCCCFNV RVATVALAIYHIVMSVLLFIEHVVEVARGKVSCRFSKMPYLR---LADLLSSFLLIGVLFIISLSLLFGVVKNREKYLIP FLSLQIMDFLLCLLTLLGSYIELPAYLKFARPR-------PGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGMPRSQFINMMLIFSVAFITVLILK--VYMFKCVWTCYRFMK-------HMNSAVE-----DSSSKL--- ----------FLKVALPSYEEALSLP----TKTPEGDLAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryctolagus_cuniculus-LAPTM5(ENSOCUP_... -------------------------------------------------------------------------------- ---------------------------------------------------------------MAPHVAAVRQTCCCFNV RVATTALAIYHVIMSVLLFIEHSVEVAQGKASCRTSKAGYLR---IADLISSFLLITMLFAISLSLLIGVVKNREKYLLP FLSLQIMDFLLCLLTLLGSYIELPAYLKFASRS------RTGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGMARSQFIKMMIIFSVAFITVLILK--VYMFKCVWRCYRLMK-------CVNLAER-----RSDSKV--- ----------PPKVALPTYEEALSPAG--PVRCSRWGRFRLNHSSGLPKTQSND-------------------------- -------------------------------------------------------------------------------- ------------------------ >Bos_taurus-LAPTM5(ENSBTAP_7204) -------------------------------------------------------------------------------- ---------------------------------------------------------------MAPRAAAIRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKFSKTGYLR---IAELVSSFLLITMLFIISLSLLVGVVKNREKYLLP FLSLQIMDFLLCLLTLMGSYIELPAYLKFASRSS----RRVSPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQDGMTHNQFIKIMIIFSIAFITVLILK--VYMFKCVWRCYRLMK-------CTNSAEE-----RSGSKM--- ----------LQKVVLPSYEEAVSLP----YKVPEGGPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris-LAPTM5(ENSCAFP_16550) -------------------------------------------------------------------------------- ---------------------------------------------------------SRDGGTMAPRTAAVRQTCCCFNV RIATTALAIYHVIMSVLLFTEHLVEVVHGKASCKVWRTGYLR---LANLISSFLLIIMLFVISLSLLIGVVKNREKYLLP FLSLQIMDFLLCLLTLLGSYIELPAYLKFASRSSRVPLRPKGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKAMN H-MNYIPSQEGVAHSQFIKMMIIFSIAFITVLILK--VYMFKCVWRCYKLMK-------YMNSAEVPKVCWSSPSTI--- ----------LLEVVLPSYEEALSLP----YKTPDGGPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Equus_caballus-LAPTM5(ENSECAP_818) -------------------------------------------------------------------------------- ---------------------------------------------------------------MAP--SSVRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQTGYLR---IADLTSSFLLIIMLFVISLSLLIGVVKNREKYLLP FLSLQIMDFLLCLLTLLGSYIELPAYLKFASRSS-----RAGPSKVPLMTLKLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGMAHSQFVKMMVIFSVAFITVLILK--VYMFKCVWRCYRFIK-------CTNSTEE-----RSSSKT--- ----------PQKVVLPSYEEAVALP----CKTPEGDPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Myotis_lucifugus-LAPTM5(ENSMLUP_1089) -------------------------------------------------------------------------------- ---------------------------------------------------------------MAPS-TAVRQTCCCFNV RIATTALAIYHVIMSVLLFIEHSVEVAHGKAACKFSRTGYLR---IADLISSFLLIAMLFVISVSLLVGVVKNREKYLLP FMSLQIMDYLLCLFTLLGSYVELPAYLKFVSRS------QANPSKVPVMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGMAYNQFIKMMIIFSVAFITVLILK--VYMFKCVWRCYKLIK-------CMNSAEE-----KSSSKM--- ----------LPKVVLPSYEEAVSLP----SKTPEVGPAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Erinaceus_europaeus-LAPTM5(ENSEEUP_8684) -------------------------------------------------------------------------------- ---------------------------------------------------------------MAP--HAVRQTCCCFNV RIATTALAIYHAIMSVLLLIEHSV-VAHGKVSCKFSKLGYLR---MADLFSSFLLITMLFVISLSLLMGVIKNREKYLLP FLSLQIMDYLLCLLTLLGYYIELPAYFKFVSRSG-----RAGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSQEGMAHSQFIKMMIIFSVAFIMILILK--VYMFKCVWRCYKLIK-------YMNLAEE-----KDRTKM--- ----------LPKVVLPSYEEALSLP----CKTSEGGLAPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Monodelphis_domestica-LAPTM5(ENSMODP_... -------------------------------------------------------------------------------- ------------------------------------------------------------LATMALRAVPTQRICYCFNV RIATTALGIYHVVMSVLLLIEHSVEVAIGKGNCKVPQTSYYK---IADIASSFLLIVMLFIISVSLLYGVLKNRERHLLP FLSLQIMDFLLCLLTLLGSYIELPAYLKFGSRGS----HTKGPFKVPLMALQLLDFCLSILTLCSSYMEVPTYLNFKSMN H-MNYLPSREGLTQDQFVKLMIGFSIAFIMVLILK--VYMFKCVWRCYKYIK-------SLNRAED-----KANTKI--- ----------FQKILLPTYEEAVALP--------SKELAPPPYSAV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus-LAPTM5(ENSOA... -------------------------------------------------------------------------------- ----------------------------------------------------------------LSNSPSIRVLFCCLLP RRQ-NSVAILSLVVSVLLLVEHAVEVSSGKGQCQVTGTRSYR---LVDIASSFLLLGMLFIVSVSLLFGVIKKRERCLLP FLSLQIMDFLLGLLTLLGTYIELPGYLRLATATR-----ARGRPKTPRVALQLLDFCLSVLALCSSYMEVPAYLNFKAMN H-MNYLPSQEGKG---FLTTMLLFSVAFVAVLTLK--VYMFKCVWRCYRDIQ-------AQQATGG-----KVTPRL--- ----------LQQVALPSYEEAVALP--------GKGARPPPYSEV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus-LAPTM5(ENSGALP_780) -------------------------------------------------------------------------------- -----------------------------------------------------------EQRDPNMTAQTKPPKCCFFNI KTATLALGIFHMVMSILLLIEYSLEVASGKGYCKDLSKDYYR---IADVTTSFLLIIMLFVISFNLLFGVVKKRERLLIP FLALQVMDFLLSLLTMFSSYIQVPAMVSVSSLR------HTEHLKTPFLALQLLDFCLSILTLCSSYMEVPTYLSLKSAD N-RGFLPALEKLPTEEYAKVMVTFTVAFIAVLFLK--AYMFKCVLSCFKYIK-------ASKREEV-----KVDTQA--- ----------VEKAVLPSYEEALELP---------SKECPPPYVAV---------------------------------- -------------------------------------------------------------------------------- ------------------------ >Taeniopygia_guttata-LAPTM5(ENSTGUP_820) -------------------------------------------------------------------------------- --------------------------------------------------------------------------CCCFNI KTATVALGIFHMVMSILLLIEYSLEVANGKGFCKDLDNNYYR---IADITTSFMLILMLFVISFHLLLGVLKKRERFLIP FLALQVIDFLLSLLTMFSSYIQVPAIISVSSLG------HTGHARTPLLALQLLDFCLSILTLCSSYMEVPTYLSLKPVD N-GGSLPALEKLPAEEYAKVMITFTIAFVAVLILK--AYMFKCVLSCFKFIK-------ASRRDEE-----KVEPHA--- ----------VEKAVLPSYEEALELP---------SK------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Xenopus_tropicalis-LAPTM5(ENSXETP_13069) -------------------------------------------------------------------------------- ---------------------------------------------------------------------PNSKMPSCFNS RTVAHTLSLYHLVMSIFLLVEKTLDVNKK-------SDRYNS---TAEVLSSYILLAILFVISLLLSCGILMKRGPLVIP FLALQFLDLISSSLMFCSVYIEQPSFQASEGVKMK---DKMSERLLQAPAQMAFDICLNLLIQCSSFSVFPSYLKLEYIN P-MNDFP-KKNMSSKKYVLDLVLFNIMYISVLILK--AIFISHIWRVFVSLH-------HKKSSKDED---AQKQQE--- ----------ISKGVLPSYEEAVRSQAI-KFPVLKSATEPNKQSVSDTGPTLC--------------------------- -------------------------------------------------------------------------------- ------------------------