>Homo_sapiens-HCK(ENSP_365012) ----------------------------------------------------------LGGRSSCEDPGCPRDEERAPRM GCMKSKFLQV-GGNTFSKTETSA--SPHCPVYVPDPTSTIKPGPNSH----------------------------NSNTP GIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMV--VLEESG-------EWWKARSLATRKEGYIPSNYVARVDSLETE EWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQEL VDHYKKGNDGLCQKLSVPCMSSKPQKP--WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANVMKTLQHDKLVKLHAVVT-KEPIYIITEFMAK------------------------------GSLLDFLKSDE GSKQPLPKLIDFSAQ-IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRIPY--PGMSNPEVIRALERGYRMPRP------ENCPEELYN-IMMRCWKN RPEERPTFE--------------YIQSVLDDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Macaca_mulatta-HCK(ENSMMUP_156) ------------------------------------------------------------------------------RM GCMKSKFLQS-GGNTFSKTETSA--NPHCPVYVPDPTSTIKPGPNSN----------------------------NRNTP GIGE-GSEDIIVVALYDYEAIHHEDLSFQKGDQMV--VLEESG-------EWWKARSLATRKEGYIPSNYVARVDSLETE EWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQEL VDHYKKGSDGLCQKLSVPCVSSKPQKP--WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKTLQHDKLVKLHAVVT-KEPIYIITEFMAK------------------------------GSLLDFLKSDE GSKQPLPKLIDFSAQ-IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRIPY--PGMSNPEVIRALERGYRMPRP------ENCPEELYN-IMMRCWKN RPEERPTFE--------------YIQSVLDDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Mus_musculus-HCK(ENSMUSP_3370) ----------------------------------------------------------LGGRSSCEDPGCPRSEGRAPRM GCVKSRFLR--DGSKASKTEPSA--NQKGPVYVPDPTSSSKLGPNNS----------------------------NSMPP GFVE-GSEDTIVVALYDYEAIHREDLSFQKGDQMV--VLEEAG-------EWWKARSLATKKEGYIPSNYVARVNSLETE EWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQEL VLHYKKGKDGLCQKLSVPCVSPKPQKP--WEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKSLQHDKLVKLHAVVS-QEPIFIVTEFMAK------------------------------GSLLDFLKSEE GSKQPLPKLIDFSAQ-ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRIPY--PGMSNPEVIRALEHGYRMPRP------DNCPEELYN-IMIRCWKN RPEERPTFE--------------YIQSVLDDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Rattus_norvegicus-HCK(ENSRNOP_12432) ----------------------------------------------------------LGGRSSCEDPGCPRGEGRVPRM GCVKSRFLR--EGSKASKIEPNA--NQKGPVYVPDPTSPKKLGPNSI----------------------------NSLPP GVVE-GSEDTIVVALYDYEAIHREDLSFQKGDQMV--VLEESG-------EWWKARSLATKKEGYIPSNYVARVNSLETE EWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQEL VVHYKKGKDGLCQKLSVPCVSPKPQKP--WEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKTLQHDKLVKLHAVVS-QEPIFIVTEFMAK------------------------------GSLLDFLKSEE GSKQPLPKLIDFSAQ-ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRIPY--PGMSNPEVIRALEHGYRMPRP------DNCPEELYS-IMIRCWKN RPEERPTFE--------------YIQSVLDDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Canis_familiaris-HCK(ENSCAFP_32817) ERTAEAEASRRGRRGFSARGAREAARRPSPSEAALCLFSKVSPSPFGCGRPGSPGAAELGGRSSCEDPGCPQEEERAPRM GCMKSKFLQ--DRGKVSKTEPSA--NSHSPVYVPDPTSANKRRPDHS----------------------------NDNLP GSKEAGPDDIIVIALYDYEAIHHEDLSFQKGDQMV--VLEESG-------EWWKARSLTTRKEGYIPSNYVARVDSLETE EWFFKGISRKDAERQLLAPGNVLGSFMIRDSETTKGSYSLSVRDYDPQHRDSVKHYKIRTLDSGGFYISPRSTFNSLQEL VAHYKKGSDGLCQKLTVPCMSSKPQKP--WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKTLQHDKLVKLHAVVT-EEPIYIITEFMAK------------------------------GSLLDFLKSSE GSKQPLPKLIDFSAQ-IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGVLLMEIVTYGRIPY--PGMSNPEVIRALERGYRMPRP------EHCPEELYN-IMTRCWKN RPEERPTFE--------------YIQSVLEDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Loxodonta_africana-HCK(ENSLAFP_28715) ------------------------------------------------------------------------------RM GCMKSKFLR--SGGKVSKTEPSS--TQQSPTYVPDPTSSGKRG-FNS----------------------------NSKLP GSSEAGAEDFVVVALYDYEAIHREDLSFQKGDQMV--VLEESG-------EWWRARSLVTQKEGYIPSNYVARVNSLETE EWFFKGISRKDAERQLLP-GNMLGSFMIRDSETTKGSYSLSIRDYDPQHGDAVKHYKIRTLDGGGFYISPRSTFSTLHEL VAHYKKGKDGLCQKLTVPCVSSKPQKP--WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANVMKTLQHDKLVKLHAVVT-EEPIYIITEFMAK------------------------------GSLLDFLKSEE GSKQPLPKLIDFSAQ-IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLTEIVTYGRIPY--PGMSNPEVIRALEHGYRMPRP------EHCPEELYN-IMTRCWKN RPEERPTFE--------------YIQSVLDDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Pteropus_vampyrus-HCK(ENSPVAP_4037) -------------------------------------------------------------------------------M GCVKSKFLR--DRGKVSKTEPSA--NTHSAVYVPDPTSSGKRRPDNS----------------------------NGNPP GSTEKGSEDIIVIALYDYEAIHHEDLSFQKGDQMV--VLEESG-------EWWKARCLATQKEGYIPSNYVARVDSLETE EWFFKGISRKDAERQLLAPGNVLGSFMIRDSETTKGSYSLSVRDYDPQHRDAVKHYKIRTLDNGGFYISPRNTFNTLQEL VAHYKKGSDGLCQKLTVPCVSSKPQKP--WEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKTLQHDKLVKLHAVVT-EEPIYIITEFMAK------------------------------GSLLDFLKSEE GSKQPLPKLIDFSAQ-IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRTPY--PGRSNPEVIRALEHGYRMPRP------EHCPEELYN-IMTRCWKN RPEERPTFE--------------YIQSVLEDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Monodelphis_domestica-HCK(ENSMODP_24291) -----------------------------------------------------------------------------PRM GCVKSRFNQ--DGRKIFKKDSPT--NNQGPVYVPDPTS-----PGKR----------------------------VSKLS GLVG-GNVDITVVALYDYEAIHNEDLSFRKGDQMA--ILEKSG-------EWWRARSLATRKEGYIPSNYVAQVNSLETE EWFFKDISRKDAERHLLAPGNVLGSFMIRDSETTKGNYSLSIRDYDPQHQDAVKHYKIRTLDNGGFYISPRSTFSTLQDL VAHYKKGSDGLCQKLTVACVVPKPQKP--WEKDAWEIPRESLKFEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFLAEANLMKTLQHDKLVKLHAVVTKEEPIYIITEFMAK------------------------------GSLLDFLKTDE GRRQPLPKLIDFSAQ-IAEGMAFIELRNYIHRDLRAANILVSSALVCKIADFGLARLIEDNLYNAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLMEIVTYGRIPY--PGMSNPEVIRSLDHGYRMPRT------ENCPEELYS-IMTRCWMN KPEDRPTFE--------------YLQSVLEDFY----------------------------------------------- ----TATESQYQKQP-------------------- >Danio_rerio-HCK(ENSDARP_75977) -------------------------------------------------------------------------------- ---------------------LF--HWCS--------------------------------------------------- ------ASENIAIALYDYEAMHEGDLGFKKGDRLR--ILQESG-------EWWKAVIISTGQEGFIPSNYVAK-DTLETE EWFFKGVSRKDAERQLLASGNKTGSFMIRDSETTKGSYSLSVRDSDHQA-DTVKHYKIRTLDNGGFYISPRITFNTLQDL VSHYKKQSDGLCQSLTSPCLSPKPQKP--WEKDAWEIPRESLKLDKRLGAGQFGEVWMAMYNKHTKVAVKTMKPGSMSVE AFLMEANLMKSLQHDKLVRLNAVVTKEEPIYIITEFMEK------------------------------GSLLDFIKSDE GNRVQLPKLIDFSAQ-IAEGMAYIEQRNYIHRDLRAANILVNKSLVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLTEIISYGRTPY--PGMTNPEVIRALERGYRMQRL------DSCPQELYD-IMLECWKN KPEDRPTFE--------------YLQSVLEDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Oryzias_latipes-HCK(ENSORLP_2943) -------------------------------------------------------------------------------- --------------------------FLT--------------------------------------------------- -----ALGESVAIALYDYEAIHEGDLGFKKGDRLK--ILEESG-------EWWKAKSISSGQEGFIPSNYVAK-DTLETE DWFFKGVSRKDAERQLLASGNKTGSFMIRDSETTRGSYSLSVRDHDPQAGDTVKHYKIRTLDNGGFYISPRITFRTLQEL VSHYKKQGDGLCQSLTSPCLSPKPEKP--WEKDAWEIPRSSLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFMMEANLMKRLQHDKLVRLNAVVTKEEPIYIITEFMEK------------------------------GSLLDFLKSDE GNRVQLPKLIDFSAQ-IAEGMAYIEQNNYIHRDLRAANILVNKALVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLTEIISYGRTPY--PGMTNPEVIRSLEKGYRMQRL------ESCPTELYD-IMLDCWKN KAEERPTFD--------------YLQSILEDFF----------------------------------------------- ----TATESQYQQQP-------------------- >Takifugu_rubripes-HCK(ENSTRUP_3758) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----LAPGEMVAVALYDYEAIHDGDLTFKKGDRLK--ILEESG-------EWWRAKLTSTGDEGYIPCNYVAK-DTLETE EWFFKGISRKDAERQLSAPGNVLGSFMIRDSETTKGSYSLSVRDS--PTGDTVKHYKIRTLDNGGFYISPRITFGTLQEL VSHYKQSSDGLCQTLTKACLNPKPEKP--WEKDAWEIPRSSLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFMAEANLMKSLQHDKLVRLNAVVTKEEPIYIITEFMEK------------------------------GSLLDFLKSDE GNRVQLPKLIDFSAQ-TAEGMAYIEQRNYIHRDLRAANILVNKALVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLTEIISYGRTPY--PGMTNPEVIRALEKGYRMQKL------DSCPPELYK-IMMECWKN KPEDRPTFD--------------YLQSVLEDFF----------------------------------------------- ----TATESQYQ----------------------- >Tetraodon_nigroviridis-HCK(ENSTNIP_20... ----------------------------------------------------------------------------AGRM GCIKSRLDGGVSK-GVEEKSSPQTVRTQLARYVRDPTSDINHN-------------------------INNSLLPGQRFQ TLEEK-GVEKIVIALYPYEALHPDDLGFKKGERMK--ILEERG-------EWWRAKSLSTNREGFIPSNYVGQADTMETE DWFFKDISRKDAERQLLAPANRAGSYLIRESETAKGSFSLSVRDVDDGGTDLVKHYKIRLLDNGGYYISPKISFTDISSM IKHYHSKADGLCRKLDRPCVKPKAEKP--WDKDAWEISKDSIRMVKRLGAGQFGEVWMAYYNNITRVAVKTLKPGTMTVE AFMDEANLMKKLQHDRLVRLYAVVTKTEPIYIITEYMAN------------------------------GSLLDFLKSDL GCSLQIPKLIDFSAQ-IAEGMAYIERRNYIHRDLRAANVLVSECLLCKIADFGLARVIEDDEYSAREG-AKFP-IKWTAP -EAINYGSFTIKSDMWSFGVLLYEIITYGKIPY--PGMTKGEVISSIQRGYRMPQP------DSCPSELYH-MMLDCWKD KPDARPTFE--------------YMQSVLNDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Tetraodon_nigroviridis-HCK(ENSTNIP_5084) -------------------------------------------------------------------------------M GCVGSKKEEKAPGKGARDLELNN--PAHTAHYVKDPTATNSRGVSERR---------------------LPWRCTTMRPF TKATLASRRATVCRSWRSGFPRRSEVFFSRVRWVIRRVLCRSG-------EWWKAKLTSTGEEGYIPSNYVAK-DTLETE EWFFKGISRKDAERQLLAPGNILGSFMIRESETTKGSYSLSVRDS--QAGDTVKHYKIRMLDNGGFYISPRITFSTLQEL VSHYRQHSDGLCQTLSKACLNPKPEKP--WEKDAWEIPRSSLKLEKRLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE AFMAEANLMKSLQHDKLVRLHAVVTKEEPIYIITEFMEKGTTRWRFF-------------TWLTRICFTGSLLDFLKSDE GNRIQLPKLIDFSAQ-VS-------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Tetraodon_nigroviridis-HCK(ENSTNIP_19... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------ADGLCQRLFAPCKPKAFQQP--WAQDEWEIPRDTLKMVKKLGAGQFGEVWMGYYKNTQKVAIKTLKEGTMEPA AFLEEANLMKQLQHERLVRLHAVVT-KEPILIVTEFMVN------------------------------GSLLDFLKSDA GKKLKVNKLIDMAAQ-IAEGMAYIEVKNYIHRDLRAANILVSETLHCKIADFGLARIIES-EYTAQEG-AKFP-IKWTAP -EAINFGTFSIKSDVWSFGILLTEIVTFGRIPY--PGMTNPEVIRNLERLYRMPRP------EGCPAELYE-VMMTCWKE KPEERPTFE--------------FLQNILNDFF----------------------------------------------- ----IATEGQYEMQP-------------------- >Gasterosteus_aculeatus-HCK(ENSGACP_4798) -------------------------------------------------------------------------------M GCVGSKKEQEPMGKGTDDGDQQS--HTLTTHYVKDPTVGIPGSKPVS----------------------------SSGSV VLGQGAVGESIAMALYDYEAIHEGDLGFKKGDKLR--ILTESG-------EWWKAKLISSGQEGFIPSNYVAK-DTLEAE EWFFKGVSRKDAERQLLAPGNRAGSFMIRDSETTRGSYSLSVRDGDPQSGDTVKHYKIRTLDNGGFYISPRNTFTTLQEL VTHYKKQGDGLCQNLTSPCLSPKPEKP--WEKDAWEIPRSSLKMDKKLGAGQFGEVWMATYNKHTKVAVKTMKPGTMSVE AFMGEANLMKTLQHDKLVRLNAVVTKEEPIYIITEYMEK------------------------------GSLLDFLKSDE GNRLQLPKLIDFSAQ-TAEGMAYIEQRNYIHRDLRAANILVNKALVCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGVLLTEIISYGRTPY--PGMTNPEVIRALEKGYRMQRQ------ESCPTELYD-IMLECWKN KPEDRPTFD--------------YLQSVLEDFY----------------------------------------------- ----TATESQYQQQP-------------------- >Homo_sapiens-LYN(uc003xsk.3) -------------------------------------------------------------------------------M GCIKSKGKDSLSDDGVDLKTQPVR-NTERTIYVRDPTSNKQQRPVP-----------------------ESQLLPGQRFQ T-KDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEEHG-------EWWKAKSLLTKKEGFIPSNYVAKLNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQADGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPRV------ENCPDELYD-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Macaca_mulatta-LYN(ENSMMUP_18594) -------------------------------------------------------------------------------M GCIKSKGKDSLNDDGVDLKTQ----------------------PVP-----------------------ESQLLPGQRFQ A-KDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEEHG-------EWWKAKSLLTKKEGFIPSNYVAKLNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQPDGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPRV------ENCPDELYD-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Mus_musculus-LYN(ENSMUSP_38838) -------------------------------------------------------------------------------M GCIKSKRKDNLNDDEVDSKTQPVR-NTDRTIYVRDPTSNKQQRPVP-----------------------EFHLLPGQRFQ T-KDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEEHG-------EWWKAKSLSSKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMSALSQGYRMPRM------ENCPDELYD-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Rattus_norvegicus-LYN(ENSRNOP_11130) -------------------------------------------------------------------------------M GCIKSKRKDNLNDDGVDMKTQPVR-NTDRTIYVRDPTSNKQQRPVP-----------------------ESQLLPGQRFQ A-KDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEEHG-------EWWKAKSLSSKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSAQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAK------------------------------GSLLDFLKSDE GSKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPRM------ENCPDELYD-IMKMCWKE SAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Canis_familiaris-LYN(ENSCAFP_10452) -------------------------------------------------------------------------------M GCIKSKRKDNLNDEGIDLKTQPVR-NTDRTIYVRDPTSNKQQRPT----------------------------LPANSPP S-QNPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEELG-------EWWKAKSLSTKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPRM------ENCPDELYD-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Loxodonta_africana-LYN(ENSLAFP_6556) -------------------------------------------------------------------------------M GCIKSKRKDNLNDDGVDLKPQPVR-NTDRTIYVRDPTSNKQQRPVS-----------------------ESQLLPGQRFQ A-KDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMK--VLEEHG-------EWWKAKSLSTKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNSPGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRRLEKACISPKPQKP--WDKDAWEIPRESIKLMKRLGAGQFGDVWMGYYNNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEYMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPQM------ENCPDELYE-IMKLCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Myotis_lucifugus-LYN(ENSMLUP_13530) ------------------------------------------------------------------------------NM GCIKSKRKDHLNDDGVDLKTQ----------------------PVP-----------------------ESQLLPGQRFQ T-KDPEEPVVIVVALYPYDGIHPDDLSFRKGEKMK--VLEEHG-------EWWKAKSLSTKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNGPGAFLIRESETLKGSYSLSVRDYDPLHGDVIKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRRLEKVCISPKPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYHNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEYMAK------------------------------GDLLDFLKSDE GGKVQLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGCFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALSQGYRMPRM------ENCPDELYE-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Monodelphis_domestica-LYN(ENSMODP_11408) -------------------------------------------------------------------------------M GCIKSKRKHSSTHDGIDLKTQPVR-NTDRTIYVRDPT-NKQQRPLPEYH-------------------LYSDLLPGQRFQ S-NDSEEE--MVIAIYPYEGLHPDDLSFKKGEKMK--VLEEYG-------EWWKAKSLSTKKEGYIPSNYVAKLNSLETE DWFFKDITRKDAERQLLLPGNRVGAYLIRESETLKGGFSLSVRDYDPLHGDVIKHYKIRSLDNGGYYISPRITFPTITDL IKHYQRQPDGLCRRLDKACISTQPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNGSTKVAVKTLKPGTMSVQ SFIEEANLMKTLQHEKLVRLYAVVTKEEPIYIVTEFMAK------------------------------GSLLDFLKSGE GTKLLLPKLIDFSAQ-IAEGMAFLERKNYIHRDLRAANVLVSESLICKIADFGLARIIRDDEYKAREG-AKFP-IKWTAP -EAINFGSFSIKSDVWSFGILIYEIITYGKVPY--PGRTNAEVIMALGKGYRMPRM------DSCPNELYD-IMSMCWKE RAEERPTFD--------------YLQSVLEDYY----------------------------------------------- ----TATEGQYQQQP-------------------- >Ornithorhynchus_anatinus-LYN(ENSOANP_... -------------------------------------------------------------------------------M GCIKSKRKDNLNDDGIDLKSQPVR-NTDRTIYVRDPTSNKQQRPVLCS---------------------DSHLLPGQRFQ S-KDPEEQGVIVVALYPYDGIHQDDLSFKKGEKLK--VLEEHG-------EWWKAKSLSTKREGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNSAGAFLIRESETQKGSFSLSIRDFDPQQGDVIKHYKIRSLDNGGYYISPRITFTCISDM IKHYQKQSDGLCRRLEKVCISPKPQKP--WDKDAWEIARESIKLVKKLGAGQFGEVWMGYYNNTTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEYMAK------------------------------GSLLDFLKSDE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSEALKCKIADFGLARIIEDNEYTAREG-AKFP-IKWTAP -EAINFGSFTIKSDVWSFGILLYEIVTYGKIPY--PGRTNADVMTALQQGYRMPRM------ENCPDELYD-IMKMCWKE KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Gallus_gallus-LYN(ENSGALP_29288) -------------------------------------------------------------------------------M GCIKSKRKANLHGDGLDLKNQ----------------------PANT----------------------DAHLLPGQIFA N-EETEEHGVIVVALYPYDGLHEDDLSFKKGEKLK--VIEELG-------EWWKARSLTTKKEGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNGPGAFLIRESETLKGSYSLSIRDYDPQHGDVIKHYKIRSLDNGGFYISPRITFPSINDM IKHYQKQSDGLCRKLEKACISPKPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYHNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAK------------------------------GSLLDFLKSDE GSRLMLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSDLLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLYEIVTYGKIPY--PGMSNSDVMVALQRGYRMPRM------ETCPAELYD-IMKTCWKD KAKERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Taeniopygia_guttata-LYN(ENSTGUP_11433) -------------------------------------------------------------------------------M GCIKSKRKENLHGDGLDLKNQPVR-KTERTIYVRDPTSNKQQRPGNP----------------------EAQLLPGQRFV N-QDAEEQGVIVVALYPYDGIHEEDLSFKKGEKLK--VIEESG-------EWWRAKSLTTRKEGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNGPGAFLIRESETLKGNYSLSIRDYDPEHGDVIKHYKIRSLDNGGFYISPRITFPNINDM IKHYQKQSDGLCRKLEKACISPKPQKP--WDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYHNSTKVAVKTLKPGTMSVQ AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAK------------------------------GSLLDFLKSDE GSKLLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSDLLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLYEIVTYGKIPY--PGMSNSDVMVALQRGYRMPRM------ETCPAELYD-IMKTCWKD KAEERPTFD--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Anolis_carolinensis-LYN(ENSACAP_17713) -------------------------------------------------------------------------------M GCIKSKRKENLHGDGNESKNIHLVRKTERTIYVRDPTSNKPQRPAN-----------------------EEILLPGQRFT K-EDRE-HRALVVALYPYDGIHEDDLSFKKGERMT--ILEEHG-------EWWRAKSLVTKNEGFIPSNYVAKVNTLETE EWFFKDITRKDAERQLLAPGNAPGAFLIRESETLKGSYSLSIRDQDAQHGDVVKHYKIRSLDNGGYYISPRITFPCISDM IKHYQKQSDGLCRKLEKACISPKPQKP--WDKDAWEIPRDSIKLVKKLGGGQFGEVWMGYYNNNTKVAVKTLKPGTMSVQ SFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITELMAK------------------------------GSLLDFLKSPE GGKVLLPKLIDFSAQ-IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGVLLYEIITYGKIPY--PGMSNSDVMVALQRGYRMPRM------EVCPVELYD-IMKTCWKD KAEERPTFE--------------YLQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Danio_rerio-LYN(ENSDARP_40554) -------------------------------------------------------------------------------M GCKKSKLDGDQNG-CVLEPVNKEHPVRTDQTYVRDPTSYKPPI-TS----------------------QNAGLLPGQVFQ KMEEK---EKIVVALYPYEAIHADDLGFKKGEKLK--IIEEHG-------EWWKARSLTTRKEGFIPSNYVAEADTMETE EWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHYKIRSLDNGGYYISPKITFSDISSM IKHYHKQSDGLCRKLDKACEKPKAQKP--WDKDAWEISKDSIKMVKKLGAGQFGEVWMAFYNNSTKVAVKTLKPGTMSVE AFLEEANLMKTLQHDRLVRLYAVVTKTEPIYIITEYMAN------------------------------GSLLDFLKSQA GSKIQLPKLIDFSAQ-IAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIEDDQYTAREG-AKFP-IKWTAP -EAINYGSFTIKSDMWSFGVLLYEIITYGKIPY--PGMSNSEVMSSVQRGYRMPRP------ENCPVELYE-IMTTCWKN KPEDRPTFD--------------YIQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Oryzias_latipes-LYN(ENSORLP_15921) -------------------------------------------------------------------------------M GCIKSILIGELTN-GVEEKGSQQAAQTDQAHYVRDPTSTSKST-RL----------------------KSNSLLPGQVFQ KLEEENKSYKIVIGLYPYEAVHSDDLGFKKGEKMK--VLEERG-------EWWKARSLTTNKEGFIPCNYVAQANTMETE EWFFKDLTRKDAERQLMAPANKPGSYLIRESETSKGSYSLSIRDRDNQGMDLVKHYKIRKLDNGGFFISPKISFNDIGSM VKHYHSKADGLCRKLESPCVKPKAQKP--WAKDAWEISKDSIKMVKKLGAGQFGEVWMAYYNNTTKVAVKTLKPGTMTVE AFLEEANIMKTLQHERLVRLYAVVTKTEPIYIITEYMAN------------------------------GSLLDFLKSEV GGKLQLPKLIDFSAQ-IAEGMSFIEKRNYIHRDLRAANVLVSESLLCKIADFGLARVIEDDEYSAREG-AKFP-IKWTAP -EAINYGSFTIKSDMWSFGVLLYEIITFGKIPY--PGMTKGEVVSSIQRGYRMPRP------ENCPTQLYE-IMTSCWKF RPEDRPTFE--------------YMQSVLDDFY----------------------------------------------- ----TATEDQYQHQP-------------------- >Takifugu_rubripes-LYN(ENSTRUP_4702) -------------------------------------------------------------------------------M GCMKSTLCESLGS-GLERKNSPQTVGAEQRHYVRDPTFEAKHNFLS----------------------QNSSLLPGQRFQ TMEDK-VVGKIMVGLYPYEALHADDLGFKKGERMK--ILEEHG-------EWWKAKSLTTNREGFIPSNYVGQADTMETE DWFFKDISRKDAERQLLAPANRPGSYLIRESETSKGSFSLSIRVVDDSGADSVKHYKIRLMDNGGYYISPKITFNDISSM IKHYHNKADGLCRNLDRPCVKPKAQKP--WDKDAWEIPKECIKMVKKLGAGQFGEVWMAYYNNTTKVAVKTLKPGTMTVE AFLDEANLMKKLQHDRLVRLYAVVTKTEPIYIITEFMAN------------------------------GSLLDFLKSDS GCTLPMPKLIDFSAQ-IAEGMAYIEKKNYIHRDLRAANVLVSESLLCKIADFGLARVIEDDEYSAREG-AKFP-IKWTAP -EAINYGSFTIKSDMWSFGVLLYEIVTYGKNPY--PGMTKGEVISSIQRGYRMPQT------DNCPTELYS-MMLNCWKE KPEERPTFE--------------YMQSVLNDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Gasterosteus_aculeatus-LYN(ENSGACP_18... -------------------------------------------------------------------------------M GCMKSRLTDGLSG-GVEGKTGEQTVHTDRMDFVKDPTSNRTSN-CA----------------------PDNFLLPGQRFQ KREEQSGVGKIVISLYPYEALHDDDLGFKKGEKMK--ILEEHG-------EWSKAKSLTTNKEGFIPGNYVAQADSMETE EWFFKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSVRDVGAEGTDSVKHYKIRTMDDGGYYISPKISFPSIAAM IKHYHHKADGLCRKLDRACVKPQAQKP--WDKDAWEISKNSIKMVRKLGAGQFGDVWMAYYNNTTIVAVKTLKPGTMTAE AFMEEANVMKTLQHDRLVRLYAVVTKTPPIYIITEYMAN------------------------------GSLLDFLKSDA GCRLQLPKLIDFSAQ-IAEGMAFIERKNYIHRDLRAANVLVSESLLCKIADFGLARVIEDDEYSAREG-AKFP-IKWTAP -EAINYGTFTIKSDMWSFGVLLFEIITYGKIPY--PGMTKGEVISSVQRGYRMPQP------GNCPNELYA-IVMLCWKN KPEDRPTFD--------------YMQSVLDDFY----------------------------------------------- ----TATEGQYQQQP-------------------- >Homo_sapiens-LCK(ENSP_362663) -------------------------------------------------------------------------------M GCGCSSHPED-DWMENID-VCENCHYPIVPLDGKG--TLLIRNGSEV---------------------RDPLVTYE--GS NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLR--ILEQSG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHEL VRHYTNASDGLCTRLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPS GIKLTINKLLDMAAQ-IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTHGRIPY--PGMTNPEVIQNLERGYRMVRP------DNCPEELYQ-LMRLCWKE RPEDRPTFD--------------YLRSVLEDFF----------------------------------------------- ----TATEGQYQPQP-------------------- >Mus_musculus-LCK(ENSMUSP_99656) -------------------------------------------------------------------------------M GCVCSSNPED-DWMENID-VCENCHYPIVPLDSKI--SLPIRNGSEV---------------------RDPLVTYE--GS LPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLR--ILEQSG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHDL VRHYTNASDGLCTKLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHPRLVRLYAVVT-QEPIYIITEYMEN------------------------------GSLVDFLKTPS GIKLNVNKLLDMAAQ-IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTHGRIPY--PGMTNPEVIQNLERGYRMVRP------DNCPEELYH-LMMLCWKE RPEDRPTFD--------------YLRSVLDDFF----------------------------------------------- ----TATEGQYQPQP-------------------- >Rattus_norvegicus-LCK(ENSRNOP_12936) -------------------------------------------------------------------------------M GCVCSSNPED-DWMENID-VCENCHYPIVPLDSKS--TLPIRTGSEV---------------------RDPLVTYE--GS LPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLR--ILEQSG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHDL VRHYTNASDGLCTKLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHPRLVRLYAVVT-QEPIYIITEYMEN------------------------------GSLVDFLKTPS GIKLNVNKLLDMAAQ-IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTHGRIPY--PGMTNPEVIQNLEKGYRMVRP------DNCPEELYH-LMMLCWKE RPEDRPTFD--------------YLRSVLDDFF----------------------------------------------- ----TATEGQYQPQP-------------------- >Canis_familiaris-LCK(ENSCAFP_15667) -------------------------------------------------------------------------------M GCSCSSNPED-DWMENID-VCENCHYPIVPLDGKA--TLPMRNGSDV---------------------RDPLVIYE--GS NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLR--ILERNG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDKGGFYISPRITFPGLHEL VRHYTNSSDGLCTRLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMEN------------------------------GSLVDFLKTPP GIKLTINKLLDMAAQ-IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTHGRIPY--PGMTNPEVIQNLERGYRMVRP------DNCPEELYQ-LMMLCWKE RPEDRPTFD--------------YLRSVLEDFF----------------------------------------------- ----TATEGQYQPQP-------------------- >Loxodonta_africana-LCK(ENSLAFP_9603) -------------------------------------------------------------------------------M GCSCSSNPED-DWMENID-VCENCHYPIVPLDSKA--MLPMRNGSDV---------------------RDPLVTYE--GS IPPASPLQDNLVIALHNYEPSHDGDLGFEKGEQLR--ILEQSG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTVGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHEL VRHYTNAPDGLCTRLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENGALQAPRSPAPLLDLSSFCSLCSLLMLLPTGSLVDFLKTPP GIKLTINKLLDMAAQ-IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTHGRIPY--PGMTNPEVIQNLERGYRMVRP------DNCPEELYD-LMLLCWKE RPEDRPTFD--------------YLRSVLEDFF----------------------------------------------- ----TATEGQYQPQP-------------------- >Erinaceus_europaeus-LCK(ENSEEUP_14558) -------------------------------------------------------------------------------M GCSCSSNPED-DWMENID-VCENCHYPIVPLDGKG--LLPMRNGSEV---------------------RDPLVTYE--GS DPPASPLQDNLVIALHSYKPSHDGDLGFEEGEQLR--ILEQNG-------EWWKAQSLTTGQEGFIPFNFVAKANSLEPE PWFFKNLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFSGLHEL VRHYTNNSDGLCTRLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD AFLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENDSFLDFQL-EKGLGAAPWGKLG-QLLLLLTGSLVDFLKTST GMKLTVSKLLDMAAQ-IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AQYA-IKWTAP -EAIN--------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Monodelphis_domestica-LCK(ENSMODP_21795) -------------------------------------------------------------------------------M GCCCSSSLDE-DWMENID-VCERCHYPIVPLDAKD--MLPMRNGSEV---------------------RDPLVDYN--GL DPPVSPLQDNLVIALHSYKPSHDGDLGFEKGEQLK--ILEQNG-------EWWKAQSLTTGQEGFIPFNFVAKVNSLEPE PWFFKDLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHEL VQHYSKVSDGLCTRLSRPCQTQKPQKP--WWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKAGSMSPD AFLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMEN------------------------------GGLVDFLKTST GVKLTIHKLLDMAAQ-IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTYGRIPY--PGMTNPEVIQN---------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Gallus_gallus-LCK(ENSGALP_10524) -------------------------------------------------------------------------------M GCVKSKEDS-----IQEKMQLGR--GKK------DPTSGSKQHDEHR----------------------------VPVPP -PVD-GSGDSVVLALYDYEAMHSGDLSFKKGERLQ--VLEQLG-------EWWQARSLLTGRKGFIPSNFVARANSLEAE EWFFKSISRKDAERQLLGPGNTLGSFMIRDSETTKGCYSLSVRDGDSLQGGSVKHYRIRTLDSGGFYISSRSSFDTLQEL VKHYKGQSDGLCRRLTYPCSVPRPQKP--WEKDAWEIPRASLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVS AFLEEANLMKSLQHDKLVRLHAVVTREEPIYIITEFMEK------------------------------GSLLDFLKSEE GNKQPLPKLIDFSAQ-IAEGMAYIEKRNYIHRDLRAANILVSAMLVCKIADFGLARIIEDNEYVAREG-AKFP-IKWTAP -EAINYGSFTIKSDVWSFGILLTEIVTYGRIPY--PGMSSAEVIRALEHGYRMPRT------ESCPEELYD-VMIRCWKT KPEDRPTFE--------------YMQSILEDFF----------------------------------------------- ----TATEGQYQKQA-------------------- >Xenopus_tropicalis-LCK(ENSXETP_11469) -------------------------------------------------------------------------------M GCGCSSEYED-DWIENFD-VCDHCHLPRQNIDAKL--TITVT-GRSV---------------------KDPLVSYT--GL NPPSSPLHDNLVVALYNYEPMHDEDLGFEAGEKLH--VLEQKD-------EWWKAKSLRTGQVGYIPYNFVASVNGIESE MWFFRDLGRKDAERQLLAPGNQQGSFLVRESETTKGSYSLSVRDLDQNQGEVVKHYKIRNLDNGGFYISPRKTFQTLQEL VQHYRRSSDGLCTLLKEPCQTQRPQKP--WWADEWEIPRNKLQLVKKLGAGQFGEVWMGYYNGHTKVAIKSLKPGTMSPE AFLAEANLMKQLQHPRLVRLNAVVT-QEPIYIVTEYMEK------------------------------GCLVDYLKTSE GLKLTIYKLIDMSAQ-VAEGMAFLEHKNYIHRDLRAANILVSESLCCKIADFGLARVIVDNEYTAKEG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGVLLTEIVTYGRIPY--PGMTNPEVIENLERGYRMPQP------DNCPMELYE-LMLRCWKE EPEERPTFE--------------FLRSLLEDFF----------------------------------------------- ----TATEGPYQSQP-------------------- >Anolis_carolinensis-LCK(ENSACAP_4189) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------QDKLVVALYDYDSTHEGDLVLRTGEQLR--VLEESG-------EWWKAQSLTTGRVGYIPSNFVAKLNSLEQE PWFFKALSRKDAERQLLTAGNTHGAFLIRESESTKGSFSLSVRDFDQDQGEVVKHYKIRNMDNGGFYISPRITFDSLHNL VEHYMRNTDGLCTRLGKPCQTQKPQKP--WWQDEWEVPRENLKLEEKLGAGQFGEVWKGMYNGHTKVAIKSLKQGSMSPE AFLAEANLMKKLRHPRLVRLYAVVT-QRPMYIITEFMEK------------------------------GNLVDFLKGSE GSRLTIYKLLDMSAQ-IAEGMAFLEKKNYIHRDLRAANILVSEAICCKIADFGLARLIEDDEYTAQEG------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------- >Danio_rerio-LCK(ENSDARP_96251) -------------------------------------------------------------------------------M G-NCGSFDPDDEFSYHPDEWCDQCNCPKPPVSQNF----------------------------------DPLIPYPSQYT PPPSSPLPENLVVAIYKYDPAHSDDLGFEKGEKMK--ILDCDDP------EWYMAESLFTGQRGYIPKNFVAKLNSMETE PWFYKNLSRNDAMRQLLAPGNTQGSFLIRESETQPGSFSISVRDLDPMQGDIIKHYRIRNMDAGGFYITNKISFNSLSEL VKHYSREADGLCTRLVKPCQTRAPQKP--WWQDEWEVPRESLKLERRLGQGQFGEVWMGLYNNNRQVAIKSLKPGTMSIS AFLAEANLMKSLQHPRLVRLFAVVT-QEPIYIITEYMEN------------------------------GSLVDFLKTPE GSDIPINTLIDMAAQ-VAEGMAYVEQKNYIHRDLRAANILVSHELTCKIADFGLARLIENNEYTAREG-AKFP-IKWTAP -EAINYGTFSIKSDVWSFGVLLTEIVTYGRIPY--PGMTNPEVIANLERGYRMPCP------DNCPEALYN-VMKHCWTE NPDNRPTFE--------------FLRSVLEDFF----------------------------------------------- ----TATEGQYQEQPC------------------- >Oryzias_latipes-LCK(ENSORLP_21875) -------------------------------------------------------------------------------M GCACSTDSE--EWLENLDDICEHCNCPIPPQSSKGKLS-------IY---------------------TDQLIQHP-SSH SPPLSPLPDNIALAVYSYEPKHDGDLGFEKGDKLK--ILNKDDP------EWYLAESLTTGQQGYIPFNFIA-MTTMETE PWFFRDISRNDAMRLLLAPGNTQGSFLIRESETTKGSYSLSIRDLDHNAGEGVKHYRIRNLDSGGFYITAKISFNSLKEL VQHYTREADGLCSTLGKPCQSRAPQKP--WWHDEWEIPRESLKLLRRLGAGQFGEVWMGLYNNDSKVAIKNLKMGTMSVE AFLAEANMMKNLQHPRLVRLFAVVT-EEPIYIVTEYMEN------------------------------GSLVDFLKTQE GGNLPINTLIDMASQ-VADGMAFIEQRNYIHRDLRAANILVSHELICKVADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINFGTFTIKSDVWSFGILLTEIVTYGRIPY--PGMSNPEVIQNLERGYRMPKP------EGCPDGLYA-IMCHCWKE TPDDRPTFE--------------YLKDVLEDFF----------------------------------------------- ----ASTERQYH----------------------- >Takifugu_rubripes-LCK(ENSTRUP_11084) -------------------------------------------------------------------------------M GCNCSSDYSDGEWIENLDEMCEHCNCPIAPQSCNPNSSSMFSP--QY---------------------TDQLIPIHSPQL SPPSSPLPDNLVVAIYSYEPKHDGDLGFEKGDKLK--IISKEDP------EWYLAESLTTGQRGYVPYNFVA-MSTMEIE PWFFKNISRNEANRRLLAPGNTQGSFLIRESETTPGSYSLSIRDLDSNVGDEVKHYRIRNMDNGGFYITAKISFNALKEL VQHYSRDSDGLCTKLVKPCQSKAPQKP--WWQDEWEIPRESLKLERKLGAGQFGEVWMGIHNNERRVAIKCLKIGTMSVE AFLAEANMMKSLQHMHLVRLFAVVT-QEPIFIVTEYMEN------------------------------GSLVDYLKTTE GSSLSINTLIDMASQ-VADGMAFIEARNYIHRDLRAANILVSHELICKIADFGLARLIENNEYTAREG-AKFP-IKWTAP -EAINYGTFSIKSDVWSFGILLTEIVTYGRIPY--PGMSNPEVIHQLEQNYRMPKP------ENCPDGLYN-FMLLCWRE KPEDRPTFD--------------YLRSVLEDFF----------------------------------------------- ----TATERQYQE---------------------- >Tetraodon_nigroviridis-LCK(ENSTNIP_1166) -------------------------------------------------------------------------------M GCNCSSDYSDAEWIENLDEICEHCNCPIAPQSCNP-VKYLCRPDLKY---------------------TDQLIGFS--QL SPPSSPLPDNLVVAIYSYNPKHDGDLGFEKGDKLK--IINKDDS------EWYLAESLTTGQRGYIPYNFIA-MSTMETE AWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFD-NNGDGVKHYRIRNMDNGGFYITTKISFNSLKEL VQHYSRDSDGLCTKLVKPCQSKAPQKP--WWQDEWEIPRESLKLERKLGAGQFGEVWMGVYNNERRVAIKCLKIGTMSVE AFLAEANMMKNLQHARLVRLFAVVT-QEPIYIVTEYMEN------------------------------GSLVDYLKTTE GSSLSMNTLIDMASQ-VGCCCCGIETQPQEDKTLRAILVMVETDRKCRVKEEGRAPLLCKSHVSARSA-GSFR-PKCHIP KEAINFGTFSIKSDVWSFGILLTEIVTYGRIPY--PGMSNPEVIQQLERNYRMPKP------DNCSDGLYS-IMLLCWRE KPEDRPTFE--------------YLRSVLEDFF----------------------------------------------- ----TATERQYQE---------------------- >Gasterosteus_aculeatus-LCK(ENSGACP_9577) -------------------------------------------------------------------------------M GCNCSSDYSDGEWMENLDEICEHCSCPIPPQSCNP-----------Y---------------------TDQLTPYP-AQH SPPTSPLPDNLVVAIYSYEPTHDGDLGFEKGDTLK--IINKDDP------EWYLAESLITGQRGYIPHNFVA-MTTVETE PWFFKNISRNEAMRLLLSPGNTLGSFLIRESETTQGSYSLSIRDLDHDTGEGVKHYRIRNMDNGGFYITAKISFSSLKEL VQHHSREADGLCTKLMKPCQSRAPQKP--WWQDEWEIPRESLKLEQKLGAGQFGEVWMGIYNNDRRVAIKNLKMGTMSVE AFLAEANMMKNLQHPCLVRLFAVVT-QEPIYIVTEYMEN------------------------------GSLVDYLKTAE GGTLPMNTLIDMAAQ-VAEGMAFIEMKNYIHRDLRAANILVSSELVCKIADFGLARLIEDNEYTAREG-AKFP-IKWTAP -EAINYGTFSIKSDVWSFGILLTEIVTYGRIPY--PGMSNPEVIQNLERGYRMPKP------ENCSDGLYG-VMGLCWKE NPDDRPTFE--------------YLKSVLEDFF----------------------------------------------- ----TATERQYQE---------------------- >Homo_sapiens-BLK(ENSP_406620) -------------------------------------------------------------------------------M GLVSSKKPDKEKPIKEKDKGQWSPLK--VSAQDKDAPPLP----------------------------PLVVFNHLTPPP PDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQ--VLKGTG-------DWWLARSLVTGREGYVPSNFVARVESLEME RWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDV-TTQGELIKHYKIRCLDEGGYYISPRITFPSLQAL VQHYSKKGDGLCQRLTLPCVRPAPQNP--WAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPE AFLGEANVMKALQHERLVRLYAVVT-KEPIYIVTEYMAR------------------------------GCLLDFLKTDE GSRLSLPRLIDMSAQ-IAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDS-EYTAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGVLLMEVVTYGRVPY--PGMSNPEVIRNLERGYRMPRP------DTCPPELYRGVIAECWRS RPEERPTFDCTPGRVTRPLCAASFVEGCNSDLARSSGVLSPSKVFRTGKRLSSSKAPVLGTPRAGRVPASAPCVDPALPR YRSQTGSRGRQQGQPQPRLRSSTAGLFCNKVTSVR >Mus_musculus-BLK(ENSMUSP_14597) -------------------------------------------------------------------------------M GLLSSKRQ-----VSEKGKG-WSPVK--IRTQDKAPPPLP----------------------------PLVVFNHLAPPS PNQDPDEEERFVVALFDYAAVNDRDLQVLKGEKLQ--VLRSTG-------DWWLARSLVTGREGYVPSNFVAPVETLEVE KWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDI-TTQGEVVKHYKIRSLDNGGYYISPRITFPTLQAL VQHYSKKGDGLCQKLTLPCVNLAPKNL--WAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPE AFLGEANVMKTLQHERLVRLYAVVT-REPIYIVTEYMAR------------------------------GCLLDFLKTDE GSRLSLPRLIDMSAQ-VAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYTAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGVLLMEIVTYGRVPY--PGMSNPEVIRSLEHGYRMPCP------ETCPPELYNDIITECWRG RPEERPTFE--------------FLQSVLEDFY----------------------------------------------- ----TATEGQYELQP-------------------- >Rattus_norvegicus-BLK(ENSRNOP_15021) -------------------------------------------------------------------------------M GLLSSKRQ-----ISEKSKS-WSPVK--ARAQGKVPPPLP----------------------------PLVVFNHLPPPS PNQHPDEEERFVVALFDYAAVNDRDLQVLKGEKLQ--VLKSTG-------DWWLARSLVTGREGYVPSNFVAPVETLEVE KWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDV-TSQGEMVKHYKIRSLDNGGYYISPRITFPTLQAL VQHYSEKGDGLCQKLTLPCVNPAPKNP--WAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPE AFLGEANVMKTLQHERLVRLYAVVT-REPIYIVTEYMAR------------------------------GCLLDFLKTDE GSRLSLPRLIDMSAQ-VAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYTAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGVLLMEIVTYGRVPY--PGMSNPEVIRSLEHGYRMPCP------ETCPPELYHDVITECWRG RPEERPTFE--------------FLQSVLEDFY----------------------------------------------- ----TATEGQYELQP-------------------- >Canis_familiaris-BLK(ENSCAFP_11788) -------------------------------------------------------------------------------M GVGSSKKQ-----VKEKEKGQWSPVK--VSTQSKDPPPLP----------------------------PLILFNHLTPAP PDACLDQEERFVVALYDYSSVNDRDLQMLKGEKLQ--ILKEAG-------DWWWARSLITGREGYVPSNFVTRVETLEVE KWFFRSISRKDAERQLLAPVNKAGSFLIRESETNKGAFSLTVKDV-TTQGEMIKHYKIRSLDEGGYYISPRITFPTLQAL VQHYSQKGDGLCQRLTQPCVSLAPQNP--WAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNVKVAIKTLKEGTMSPE AFLGEANLMKTLQHERLVRLYAVVT-KEPIYIVTEYMAR------------------------------GCLLDFLKTVE GSRLSLPRLIDMSAQ-IAEGMAYIEQMNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYTAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGILLMEIVTYGRVPY--PGMSNPEVIRSLERGYRMPRP------DSCPPELYHGVIAECWRS RPEERPTFE--------------FLQSVLEDFH----------------------------------------------- ----TATEQQYELQP-------------------- >Loxodonta_africana-BLK(ENSLAFP_5724) -------------------------------------------------------------------------------M GVVSSKKQ-----VKEKDKGRWSPLR--ISTQSKAPPPLP----------------------------PLVVFNHLASPP ADKHLDREEHFVVALYDYNAVDDQDLQMLKGEKLQ--ILKETG-------DWWLAKSLITGREGYVPSNFVARVETLEVE KWFFRSISRKDAERQLLAPINKVGSFLIRENETNKGAFSLSVKDV-TTQGEVIKHYKIRVLDEGGYYISPSITFPSLQDL VQHYSKNGNGLCQRLMLPCVSLAPQKP--WVQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNVKVAIKTLKEGTMSPE AFLGEANMMKTLQHERLVRLYAVVT-KEPIYIVTEYMAR------------------------------GCLLDFLKTDE GSRLSLPRLIDMSAQ-IAEGMAYIEQRNSIHRDLRAANILVSETLCCKIADFGLARIIDS-EYIAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGILLMEIVTYGCVPY--PGMSNPEVIRSLEQGYRMPRP------DSCPPELYSGVISKCWRS RREERPTFE--------------FLQSVLQDFY----------------------------------------------- ----TATEQQYESSP-------------------- >Pteropus_vampyrus-BLK(ENSPVAP_2779) -------------------------------------------------------------------------------- ----------------------------------------------------------------------IMFNHLAPAP PDTCPDQEEHFVVALYDYSAVNDRDLQMLKGEKLQ--ILKEAG-------DWWLAKSLVTGREGYVPSNFVARVETLEVE KWFFRSISRKDAERQLLAPINKAGSFLIRESETNKGAFSLSVKDV-TAQGEMIKHYKIRSLDEGGYYISPRVTFPALQDL VQYYSKKGDGLCQRLTQPCVNLAPQNP--WAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNTKVAIKTLKEGTMSPE AFLGEANLMKTLQHERLVRLYAVVT-KEPIYIVTEYMAR------------------------------GCLLDFLKTDE GSRLSLSRLIDMSAQ-IAEGMAYIEKMNSIHRDLRAANVLVSETLCCKIGDFGLARIIDS-EYTAQEG-AKFP-IKWTAP -EAIHFGVFTIKADVWSFGILLMEIITYGRVPY--PGMNNPEVIRCLERGYRMPRP------DSCPPELYHGVIAECWRS RPEERPTFE--------------FLQSVLEDFQ----------------------------------------------- ----TATERQYELQP-------------------- >Monodelphis_domestica-BLK(ENSMODP_15019) -------------------------------------------------------------------------------M GVVSSKKL-----AKEKGKNQWNFKEPHIVFPKTPPPPLP----------------------------PLVVFNHLTTPT PVLKPDQEEHYAVALWDYEATNDRDLKVVKGEKLQ--ILMKTG-------DWWLARSLVTKREGYVPSNFVTQVETLEVE KWFFKTISRREAERELLAPVNKTGAFLIRESETIKGAYSLTVKDT-TSAGNVIKHYKIRALDDGGYYISPRVTFPSLREL VQHYSKKGDGLCQKLTMPCMILAPQTQ--WAQDEWEVPRHSLKLVRKLGAGQFGEVWMGYYKNNIKVAIKTLKEGSMSPE AFLAEANLMKTLQHDKLVRLYAVVT-QEPIYIVTEYMAK------------------------------GSLLDFLKSEE GCKLPFSRLIDIMAQ-IAEGMAYIEQRNSIHRDLRAANVLVSESLGCKIADFGLARIVDS-EYTAHEG-AKFP-IKWTAP -EAINFGVFSIKSDVWSFGILLMEIVTYGRIPY--PGMTNPEVIRNLERGYRMPCP------EMCPAELYS-IISKCWRN RPEERPTFE--------------YLQSVLEDFY----------------------------------------------- ----IATEQQYELQP-------------------- >Gallus_gallus-BLK(ENSGALP_26839) -------------------------------------------------------------------------------M GLIGSKNQL---MSNEKFTSGSNPKN---RSRPPPAPPKS----------------------------KLTFNSALPKPS AHQSPAEYDTIVIALYDFAASSDRDLELVKGEKLQ--ILSNEG-------DWWLAKSLRSGKKGYIPSNFVALVDSLEQE KWFFKTLSRKDAERLLLSSGNKVGSFLVRESETSTGAYSLSVRDSDSAHGDIIKHYRIRSLDGGGYYISPRMTFATLPEL IHHYSQRGDGLCQRLMAPCTSLAPQRP--WAQDEWEIPRESLKLVKKLGSGQFGEVWMGYYKNNFKVAVKTMKEGSMDPE AFLAEANLMKKLQHNKLVRLYAVVT-KQPIYIVTEYMAN------------------------------GCLLDYLKTEE GSQLNLPKLIDMSAQ-VAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIED-EYLAQEAGAKFP-IKWTAP -EAINFGVFTIKSDVWSFGILLTEIITYGRIPY--PGMTNPEVIRNLEQGYRMPCP------DMCPAELYS-IILRCWRN KPEERPTFE--------------YLQSVLEDFY----------------------------------------------- ----TATEKQYEAEPQP------------------ >Taeniopygia_guttata-BLK(ENSTGUP_13694) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------VIALYDFPASNDRDLELVKGEKLQ--VLSKEG-------DWWLAKSLNSGRKGYIPSNFVAQVDSLEQE KWYFRTLSRKDAERLLLSSGNKVGSFLVRESETTKDAYSLSVRDNSSAHGDIIKHYRIRSLDGGGYYISPRMTFSSLPEL IHHYSREGDGLCQRLTAPCTSLVPQRP--WAKDEWEIPREALKLVKKLGSGQFGEVWMGYYKNNIKVAVKTMKEGSMDPD AFLAEANLMKKLQHNKLVRLYAVVT-KQPIYIVTEYMAN------------------------------GCLLDFLKTEE GSQLNLPKLIDISAQ-VAEGMAYIERMNFIHRDLRAANILVSETLCCKIADFGLARLIEN-EYLAQEG-AKFP-IKWTAP -EAINYGVFTIKSDVWSFGILLTEIITFGRIPY--PGMTNPEVIRNLERGYRMPCP------ESCPGELYS-IILKCWRS IPEERPTFE--------------YLQSVLEDFY----------------------------------------------- ----TSTEKQYEPEP-------------------- >Anolis_carolinensis-BLK(ENSACAP_11257) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------KHCVIAQHDFVPSSERDLPLTAGERFE--VLCSNG-------DWWLAKSLTTKKIGYIPSNFVVRFNSLEEE KWFFKGLSRKETERFLMAPRNAVGSFLIRESETTPDAFSLSIRDS-TSQGDVIKHYKIRKMDNGGYYICPKAMFFSLPEL VKHYSVHQGGLCQRLREPCISLTPQIP--WATDEWEIPRSTLKLIKKLGSGQFGEVWMGYYKNNVKVAIKTLKEGSMSPD AFLAEANLMKQLQHSKLVRLHAVVT-EQPIYIITEYMAN------------------------------GSLLDYLQTEE GKKLNLPRLIDMAAQ-VAEGMAYIERMNSIHRDLRAANILVSATLCCKVADFGLARIIED-EYFAQEG-TKFP-IKWTAP -EAINYGVFTIKSDVWSFGILLTEIITYGRCPY--AAMTNPEVIQKLEQGYRMPCP------DSCPPELYA-MMLKCWRG KAEERPTFE--------------YLQSTLEDFY----------------------------------------------- ----TSTEMQYQPEP-------------------- >Danio_rerio-BLK(ENSDARP_8826) -------------------------------------------------------------------------------M GCACSDQNH-------------------PKGHEHYNSTNS----------------------------KTSHASRDHKKQ NN---NQDEDVVIAQYDFQPASENDLQFKKGDRLR--IIKENG-------EWWLAKSLVTGYEGFIPSTYVARAQTLQVE RWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVKHYKIRALDNGGYYISPSTSFSSLQEL VKYYSRTADGLCQRLGNPCKSTAPQRP--WAQDEWEIPRETLKLVKKLGAGQFGEVWMGFYKNNQKVAIKTLKEGTMEPE AFLQEANLMKQLQHERLVKLHAVVT-REPIYIVTEYMAN------------------------------GSLLDFLKTDD GHKLKLSKLIDMTAQ-IAEGMAYIERKNYIHRDLRAANILVSETLHCKIADFGLARIIET-EYTAQEG-AKFP-IKWTAP -EAINYGTFTIKSDVWSFGILLTEIVTYGRVPY--PGMTNPEVIRNLDRNYRMPCP------DACPGELYD-IMTKCWME KPEDRPTFE--------------YLQDTLNDFF----------------------------------------------- ----IATEGQYEMQP-------------------- >Oryzias_latipes-BLK(ENSORLP_20477) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------DVFVAQHDFKATNGSDLSFKKGDKLK--ILHERG-------EWCLAKSISTGDEGYIPSNYVARADSLEVE KWFFKDVSRRETERLLLAPGNKPGTFLIRESETSKGSYSLSIRDHDQQQGDVVKHYKIRCLDKGGFYISPSTTFSSLSEL VKYYSRTADGLCERLNSPCKPKDPQEP--WAHDEWEIPRDTLKMTKKLGAGQFGEVWMGYYKNTQKVAIKTLKEGTMEPE AFLQEANLMKQLQHDRLVRLHAVVT-KEPILIVTEYMVN------------------------------GSLLDFLKSDE GGKLKMNKLIDMSAQQIAEGMAYIEKKNYIHRDLRAANILVSETLHCKIADFGLARIIET-EYTAQEG-AKFP-IKWTAP -EAINFGTFTIKSDVWSFGILLTEIVTYGRIPY--PGMTNPEVVRCLDQSYRMPRP------DDCPVELYD-IMMMCWRQ RPEERPTFD--------------FLQNTLNDFF----------------------------------------------- ----IATEGQYEMQP-------------------- >Takifugu_rubripes-BLK(ENSTRUP_15829) -------------------------------------------------------------------------------M GCTCSGQNK-------------------VKDDKRRHKGQG----------------------------NHTSEH------ ----------VFVALHDFKSTNSSDLPFKEGDKLK--VLQSDG-------QWWVAKSLESGLEGFIPCNYVARAETMEME KWFFNDMSRKETERLLLAPGNQTGSFLVRESETSPGSYSLSIRDYEPQQGDVVKHYKIRTMDKGGYYISPYNTFPTLQKL VTYYTGTADGLCQQLYAPCKPKATQQP--WAHDEWEIPRETLKMVKKLGAGQFGEVWMGYYKSTQKVAIKTLKEGTMEPA AFLQEANLMKQLQHERLVRLHAVVT-KEPILIVTEFMVN------------------------------GSLLDFLKSDE GKKLKVNKLIDMAAQ-IAEGMAYIEVKNYIHRDLRAANILVSETLHCKIADFGLARIIES-EYTAQEG-AKFP-IKWTAP -EAINFGTFSIKSDVWSFGILLTEIVTFGRTPYPAPGMTNPEVIRSLDRSYRMPCP------DSCPVELYD-VMMMCWKQ KAEERPTFE--------------FLQTTLNDFF----------------------------------------------- ----IATEGQYEMQP-------------------- >Gasterosteus_aculeatus-BLK(ENSGACP_14... -------------------------------------------------------------------------------M GCSWSGQKR-------------------VKGDN-FYKGKQ----------------------------NHEASNPSNHIV SGPVVKETLDVFVAQHDFKATNNSDLPFKKGDKFK--VLQENG-------EWWLAKSLTTGEEGMIPCNYVARADTLEVE KWFLKDVSRRQTEQLLLAPGNKPGAFIVRASETCKDSFSLSVRDYVKEQGDVVKHYKIRCLDKGGYYIAPTNTFPSLQEL VNYYTGTADGLCQRLQAPCKVKAPEPP--WAQDEWEIPRETLKLVKKLGAGQFGEVWMGYYKNTQKVAVKTLKEGTMEPE AFLQEANLMKQLQHERLVRLHAVVT-KEPILIVTEFMVN------------------------------GCLLDFLKSNE GKKLKLNKLMDMSAQ-IAEGMAYIERKNYIHRDVRAANILVSDTLTCKIADFGLARIIET-EYTAQEG-AVFPRIKWTAP -RPQ-FGTFSIKSDVWSFGILLTEIVTYGRIPY--PGMTNPEVISSLDKLYRMPCP------DACPKELFD-IMNMCWRQ KPEERPTFD--------------FLQNTLNDYF----------------------------------------------- ----IATEGQYEMQP-------------------- >Ciona_savignyi-HCK(ENSCSAVP_16773) -------------------------------------------------------------------------------M GCCTSKEKDNGGVTSVDGGTHYARDPGINSNPVVISGPQMSSGPVSDSSRNTNQFGGFNPGQMPLFNQTQSGMVPIKGMP SRPSMTGQAVRYVALYDYDARTADDLSFKKGEQLF--ILNS------TEGDWWEARSLITQDTGYIPSNYVAPANSVQCE EWFFGKIGRKDSERLLMNQENIRGTFLIRESETAQGTFSLSILDEDQAKGLNVKHYRIRKLDSGGFYITARAQFETLKHL VDHYQNVADGLCCRLLDPCPLLEKPQTITIARDVWEIPRESLKLEKKLGAGMFGEVWKGLWNGTTEVAIKTLKPGTMSPE AFLAEAKIMKMLRHEKLVSLYAVVS-KEPIYIVTEYMCH------------------------------GSLLDYLKEGQ GHKSNLVDQIDMAAQ-IAGGMAYIERMNYIHRDVRAANILVGKNQVCKIADFGLARLIVDDEYSARQG-AKFP-IKWTAP -EAAMYGKFTIKSDVWSFGILLTEIVTKGRIPY--PGMMNREVLEQVERGYRMPKPTLLPNDPPCPDSLYD-LMLQCWN- -------------------------------------------------------------------------------- ----------------------------------- >Ciona_savignyi-HCK(ENSCSAVP_11139) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----APNVGKFVAMFDYDARTKEDLPFKKGENLI--ILNSSRKYHNSEGEWWHARSPTTGQTGYVPSNYLALAGGLESE IWFFGKISRKECERTMKQSQ--RGTFMVRESENDPGAHSLSITDQVEENRSIIKHYKIRKLDNGGYYITTRAQFTDLVEL VNHYQKTADGLCCRLLEPCPKTAKPGGVGLGRDVWEIDREQLTLQKKLGAGMFGEVWKGLWNGTTEVAIKTLKPGTMSPE AFLEEAKIMKMLRHEKLVNLYAVVS-TEPIYIVTEFMCH------------------------------GSLLDYLREGP GVDSNLVDQIDIASQ-IAAGMAFIELNNYIHRDVRAANILVGSSQICKVADFGLARLIEDDETSTP-G-SKFP-IKWTAP -EAATHGRFTIKSDVWSFGILLTEIVTKGRIPY--PGMKNATVLMRVESGYRMPKPPIQPPQAPCPDSLYE-LMLQCWHR DEMQRPTFE--------------YLQVFLEDYF----------------------------------------------- ----TATEPHYQESGEGA----------------- >Branchiostoma_floridae-HCK(7400010) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------MPITKD----------------------------------- LSHHT--------------------------KDAWEIDRESISLKEKLGQGNFGEVWLAVWNHSTKVAVKTLRSGSMSPQ AFLEEATIMKKLRHEKLVALYAVCTDREPIYIITEYMCN------------------------------GSLLDYIVKGD GQKSGLKELVDMGAQ-IAFGMAYIERMKYVHRDLRAANVLVGDDNNCKIADFGLARLIEDDLYKAQQG-AKFP-IKWTAP -EAALYGKFTIKSDVWSFGILLTELVTHGKIPY--PGMMNREVLDQVERGYRMPQP------QGCPDSLYN-LMLQTWAR DEETRPTFE--------------YLHNFLDDYF----------------------------------------------- ----TATEPNYREPDSI------------------ >Ciona_intestinalis-HCK(ENSCINP_17456) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------VAMYDYDARTHEDLSFRKGETLF--ILNN-------EGDWWQARSAASGQEGYVPSNYVAPAGGLDCE EWFFGKISRKECERKLIQHRTPRGTFMIRESETAPGTYSLSITDQDQGKGSTVKHYRIRQLDNGGYYITTRAQFQDLVGL ISHYQNSADGLCCRLTNPCPKNEKPETSGIAPDVWEIDREQLTLQKKLGAGMFGEVWKGLWNSTTEVAIKTLKPGTMSPE AFLEEAKIMKMLRHEKLVNLYAVVS-CEPIYIVTEFMCH------------------------------GSLLDYLKDGA GRHSNLVDQIDMAAQ-IAAGMAFIERNNYIHRDVRAANILVGKNQVCKVADFGLARLIEDDEYNAQQG-SKFP-IKWTAP -EAATHGRFTIKSDIWSFGILLTEIVTKGRIPY--PGMMNREVLERVETGYRMPKPPIQPPQPPCPDSLYE-LMLQCWHR DDMQRPTFE--------------YIQGFLEDYF----------------------------------------------- ----TATEPHYQESG--------------------