>Homo_sapiens-EYA1(ENSP_342626) -------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTP N--GTE--------------------------VKTEPMSSSETAST---TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQ IYPSNRPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGISSYG---------------- ---------------ALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS-YQMQ----GSSFTT-SSGIYTGN NSLTNSSGF--NSSQQ-DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGITSQAVTDP-T------------AEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRISSHSDLMALHHALELEYL >Macaca_mulatta-EYA1(ENSMMUP_9947) -------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLDNSHINSNSMTP N--GTE--------------------------VKTEPMSSSETAST---TADGSLDNFSGSAIGSSNFSPRPTHQ-SPPQ IYASNRPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGISSYG---------------- ---------------ALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS-YQMQ----GLSFTT-SSGLYTGN NSLTNSSGF--NSSQQ-DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGITSQAVTDP-T------------AEYNTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNIGC ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRISSHSDLMALHHALELEYL >Mus_musculus-EYA1(ENSMUSP_27066) -------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLDSSHINSTSMTP N--GTE--------------------------VKTEPMSSSEIAST---AADGSLDSFSGSALGSSSFSPRPAHPFSPPQ IYPS-KSYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGISSYG---------------- ---------------ALWAGIKTESGLSQSQSPGQTGFLSYGTSFGTPQPGQAPYS-YQMQ----GSSFTT-SSGLYSGN NSLTNSSGF--NSSQQ-DYPSYPGFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGVTSQAVTDP-T------------AEYSTIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRVSSHSDLMALHHALELEYL >Rattus_norvegicus-EYA1(ENSRNOP_63439) -------------------------------------------MEMQDLTSPHSRLSGSSESPSGPKLDSSHINSTSMTP N--GTE--------------------------VKTEPMSSSEIAST---AADGSLDSFSGSALGSSSFSPRPAHPFSPPQ IYPS-KPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQHYGISSYG---------------- ---------------ALWAGIKTEGGLSQSQSPGQTGFLSYGTSFGTPQPGQAPYS-YQMQ----GSSFTT-SSGLYTGN NSLTNSSGF--NSSQQ-DYPSYPGFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGVTSQAVTDP-T------------AEYSTIHSPSTPIKESDSDRLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSR----ANCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRVSSHSDLMALHHALELEYL >Canis_familiaris-EYA1(ENSCAFP_11706) REWSSARPERSKGRRKPVDAAAVSAVQTSQTSSDVAVSSSCRSMEMQDLTSPHSRLSGSSESPSGPKLDNSHRNSNSMTP N--GTE--------------------------VKTEPMSSSEIVST---TADGSLDNFSGSAIGSSSFSPRPTHQFSPPQ IYPS-KPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGISSY----------------- -------------------GIKTEGGLSQSQSPGQTGFLSYGTSFGTPQPGQAPYS-YQMQ----GSSFTT-SSGLYTGN NSLTNSSGF--NSSQQ-DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGITSQAVTDP-A------------AEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRISSHSDLMALHHALELEYL >Monodelphis_domestica-EYA1(ENSMODP_9035) -----------------------------------------RSMEMQDLTSPHSRLSGSSESPSGQKLDNAHINSSSMTP N--GTEGELSLFL-------------------VKTEPMSSSEIATT---AADGSLDNFSGSAIGSSGFSPRQTHQFSPPQ IYPS-KPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGIPSYDKLLLT----------- ------------DLGALWAGIKTEGGLSQSQTPGQTGFLSYGTSFSTPQPGQAPYS-YQMQ----GFSFTT-SSGLYTGN NSLTNSSGF--NSSQQ-EYASYTSFGQGQYAQYYNSSPYPSHYMTSSNTSPTTPS-----------TNATYQLQEP---- ----PSGITSQA--------------------YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG NFCLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGVVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRISSHSDLMALHHALELEYL >Gallus_gallus-EYA1(ENSGALP_25135) -------------------------------?SDVAVSSSCRSMEMQDLASPHSRLSGSSESPSGPKLDNSHINNNSMTP NGTE----------------------------VKTEPMSSSEIATTTTTTTDGSLDNFSGSAIGSSGFSPRQTHQFSPPQ IYPS-KPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYATYPQPGQPYGIPSYG---------------- --------------------IKTEGGLSQSQSPGQTGFLSYGASFSTPQPGQAPYS-YQMQ----GSSFTT-SSGIYAGN NSLTNSTGF--NSSQQ-EYPSYPSFGQGQYAQYYNSSPYPSHYMTNSNTSFTTPS-----------TNATYQLQEP---- ----PSGITSQAVTDPAA------------AEYSTIHSPSTPIKDSDSDRLRRSSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIIFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGVVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRISSHSDLMALHHALELEYL >Xenopus_tropicalis-EYA1(ENSXETP_34849) -------------------------------------------MEMQDLASPHSRLSGSGDSPSGTGLDNSHINSNSMTP N--GTE--------------------------VKTEPMSSSDIVTT---TADGHLDNFSGSVIGSSGYSPRQAQQFSP-Q IYPSNRAYPHILPNPSSQTMAAY-GQTQFSS---------GMQQATAYATYPQPGQPYGIPPYG---------------- ---------------ALWAGIKTEGGLPQPQSPGQTGFLSYGSSFSTPQPGQAPYS-YQMQ----GSSFTT-ASGIYAGS NSLTNSTGF--NSSQQ-EYPSYPSFGQGQYAQYYNSSPYPSHYMTSSNTSPTTPS-----------TTATYQLQEP---- ----PSGITSQAVTDHST------------AEYSTIHSPSTPIKDSDSDRLRRSSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----SNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVVGDGVEEEQGAKKHS---MPFWRITSHSDLMALHHALELEYL >Anolis_carolinensis-EYA1(ENSACAP_14511) -------------------------------------------------------------------------------- --------------------------------VKTEPMSSSEIATT---TADGSLDSFSGSAIGSSSFSPRQTHPFSPPQ IYPSNRPYPHILPTPSSQTMAAY-GQTQFTT---------GMQQATAYSTYPQPGQPYGISSYG---------------- --------------------IKTEGGLSQTQSPGQTGFLSYGAGFSTPQPGQAPYS-YQMQ----GLSFTT-SSGIYAGN NSLTNSTGF--NSSQQ-EYPSYPSFGQGQYAQYYNSSPYPSHYMTSSNTSPTTPS-----------SNATYQLQEP---- ----PSGITSQAVTDP-T------------AEYSTIHSPTTPIKDSEADRLRRSSDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFGTDGFPAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGG K-CLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----TNCVNILVTTTQLIP--ALAKVLLYGLGVAFPIEN IYSATKIG-KESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHA---MPFWRITSHSDLMALHHALELEYL >Oryzias_latipes-EYA1(ENSORLP_10103) ---------------------------------------SARSMEMQDLASPHSRVSGSSESPNGPNLDNSHITNNSMTP N--GTEV--------------------------KTEPMSSGEIASS----VADPLDSFSGSAIGTSGFSPRQTHQFSP-Q IYPSNRTYPHILPTPSSQNMAAY-GQTQYTT---------GMQQAAAYASYPQPGQPYGISAY----------------- -------------------GIKTEGGLSQSQSPGQTGFLSYSSGFTTPQTGQAPYS-YQMQV-SKGGTFTT-TSGLYAGN NSLTNSAGF--NSAQQ-EYPSYPGFGQGQYAQYYNSSPYTSPYMTSNNTSPSTPS-----------TTTTYTLQEP---- ----PTGITSQALTDNPA------------GEYSTIHSPSTPIKDSDSDRLRRASDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFSADGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGG ---LLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSR----SNCVNILVTTTQLIP--ALAKVLLYGLGVVFPIEN IYSATKIG-KESCFERVIQRFGRKVVYIVVGDGVEEEQGSKKHN---MPFWRISSHSDLMALHHALDLEYL >Takifugu_rubripes-EYA1(ENSTRUP_31148) -----------------------------------------RSMEMQDLASPHSRVSGSSPQMSQP--DNSHISHNSMTP N--GTEA----------YLF-----------AVKTEPMSSSDIATS----VADSLDSFSGSAIGTSGFSPRQTHQFSP-Q IYPSNRTYPHILPTPSSQNMAAY-GQTQYTT---------GMQQAAAYASYPQPGQPYGIPAYD---------------- -------------LGPLWAGIKTEGGLSQSQSPGQTGFLSYGSGFTTPQTGQAPYS-YQMQ----GGTFTT-TSGLYAGN NSLTNSTGF--NSTQQ-DYHSYPTFGQGQYAQYYNSSPYPSPYMTSNNTSPNTPS-----------TTTTYTLQEP---- ----PPTITSQALTENPA------------GEYSTIHSPSTPIKDSDSDRLRRASDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFAADGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGG ---LLGPAKREAWLQLRTEIEALTDSWLTLALKALTLIHSR----SNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERVIQRFGRKVVYIVVGDGVEEEQGSKKHN---MPFWRISSHSDLMALHHALDLEYL >Tetraodon_nigroviridis-EYA1(ENSTNIP_1... -------------------------------------------MEMQDLASPHSRVSGSSESPNGPNLDNSHINNNSMTP N--GTEGDNITMLTTADWLLGSNSQST----AVKTEPMSSSEIATS----VADSLDGFSGSAIGTSGFSPRQTHQFSP-Q IYPSNRTYPHILPTPSSQNMAAY-GQTQYTT---------GMQQAAAYASYPQPGQPYGIPAY----------------- -------------------GIKTEGGLSQSQSPGQTGFLSYGSGFTTPQTGQAPYS-YQMQ----GGTFSNNVLGLYAGN NSLTNSTGY--NSTQQ-DYHSYPAFGQGQYAQYYNSSPYPSPYMTSNNTSPSTPS-----------TTTTYTLQEP---- ----PPAITSQALTENPA------------GEYSTIHSPSTP-KDSDSDRLRRASDGKSRGRGRRNNN---------PSP PPD-------------SDLERVFIWDLDETIIVFHSLLTGSYANRYG--RDPPTSVSLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFAADGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGG ---LLGPAKREAWLQLRTEIEALTDSWLTLALKALTLIHSR----SNCVNILVTTTQLIP--ALAKVLLYGLGIVFPIEN IYSATKIG-KESCFERVIQRFGRKVVYIVVGDGVEEEQGSKKSNSTTCPFWRISSHSDLMALHHALDLEYL >Homo_sapiens-EYA2(ENSP_353866) -------------------------------------------------------------------------------- ----------------------------MRYKEMVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVS QLF-SRSCPRVLPRQPSTAMAAY-GQTQYSA---------GIQQATPYTAYPPPAQAYGIPSYS---------------- --------------------IKTEDSLN--HSPGQSGFLSYGSSFSTSPTGQSPYTYQ-MHG----------TTGFYQGG NGLGNAAGF--GSVHQ-DYPSYPGFPQSQYPQYYG-SSYNPPYVPASSICPSPLS-----------TS-TYVLQEA---- ----SHNVPNQSSESLAG-------------EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD---------PSP AGD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSADGFHSSAPG---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGG ---LIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGSVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Macaca_mulatta-EYA2(ENSMMUP_38074) -------------------------------------------------------------------------------- ----------------------------FRYKEMLELVISASLTVNSACLEKLKFHRAGVTVWTLSDREGITRSAPLRVS QLF-SRSCPRVLPSQPSTAMAAY-GQTQYSA---------GIQQATPYTAYPPPAQAYGIPSYS---------------- --------------------IKTEDSLN--HSPGQSGFLSYGSSFSTPPTGQSPYTYQ-MHG----------TTGFYQGG NGLGNAAGF--GSVHQ-DYPSYPGFPQSQYPQYYG-SSYNPPYVPASSICPSPLS-----------TS-TYVLQEA---- ----SHNVPNQSSESLAG-------------EYNAHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD---------PSP AGD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSADGFHSSAPG---TNLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRQP-QPNCVNVLVTTTQLIP--ALAKVLLYGLGSVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYVVIGDGVEEEQGAKK----------------------------- >Mus_musculus-EYA2(ENSMUSP_66244) -------------------------------------------------------------------------------- ---------------------------------MLEVVTSPSLATSSD------WSEHGAAVGTLSDREGIAKSAALSVP QLF-VKSHPRVPPGQSSTAMAAY-GQTQYST---------GIQQAPPYTAYPTPAQAYGIPPYS---------------- --------------------IKTEDSLN--HSPSQSGFLSYGPSFSTAPAGQSPYTYP-VHS----------TAGLYQGA NGLTNTAGF--GSVHQ-DYPSYPSFSQNQYPQYFS-PSYNPPYVPASSLCSSPLS-----------TS-TYVLQEA---- ----PHNVPSQSSESLAG-------------DYNTHNGPSTPAKEGDTERPHRASDGKLRGRSKRNSD---------PSP AGD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSTDGFHSTAPG---ASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGSVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Rattus_norvegicus-EYA2(ENSRNOP_30502) -------------------------------------------------------------------------------- ---------------------------------MLEVVISPSLAASSD------WGEHGAAVGALTDREGTAKAASLSVP QLF-AKSHPRVPPGQSSAAMAAY-GQTQYST---------GIQQTPPYTAYPPPAQAYGIPPYS---------------- --------------------IKTEDSLN--HSPSQSGFLSYGPSFSTAPAGQSPYTYP-VHS----------TAGLYQGA NGLTNTAGF--GSVHQ-DYPSYPNFPQNQYPQYFS-PSYNPPYVPASSLCSSPLS-----------TS-TYVLQEA---- ----PHNVS-QSSESLAG-------------DYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSD---------PSP AGD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSTDGFHSTAPG---ASLCLGTGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGSVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Canis_familiaris-EYA2(ENSCAFP_15723) -------------------------------------------------------------------------------- ---------------------------------MLELVISPSLTVNSDRPGKLKLNRPAADVRTLSDVEGVTTSAPPSVS QFF-SRPCPRALPSQPATAMAAY-GQTQYSA---------GIQQAAPYTTYPPPAQAYGIPSYS---------------- --------------------IKTEDSLN--HSPSQSGFLSYGSSFSTPPTGQSPYTYQ-MHG----------TAGIYQGA NGLTNAAGF--GSVHQ-DYTSYPGFPQSQYSQYYS-SSYSPPYVPASSICPSPLS-----------TS-TYVLQEA---- ----SHSVPNQSSELLGG-------------DYNTHNGPSTPAKEGDADRPHRASDGKLRGRSKRSSD---------PSP AGD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSADGFHSSAPG---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGSVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Monodelphis_domestica-EYA2(ENSMODP_20... -------------------------------------------------------------------------------- ---------------------------------MLDLVISPSLTVNSHYSDRLTSNLSDIGALSPHDIGGRLMVSLWFVL DMH-IRSCPRFLSSFSFSSRATY-GQTQYSA---------GIQQSTAYSPYPPPAQAYGIPSYS---------------- --------------------IKTEDSLN--HSPGQSGFLSYGSSFGTPPTGQTPYTYQ-MHG----------ASGIYQGA NGLTNSAGF--GTMHQ-EYPSYPGFPQSQYSQYYS-SSYNSPYVSANSISPSPLS-----------TS-TYALQES---- ----SHNITSQSSESLAV-------------EYSTHNGPPTPAKDGETDRPHRGSDGKLRGRSKRSND---------PSP TVD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSADGFHSSAAG---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNMYKNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHALKALNLIHSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGTVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Ornithorhynchus_anatinus-EYA2(ENSOANP... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------LSARPFSNMAAY-GQAQYSA---------GIQQAAAYTAYPP-AQAYGIPSYS---------------- --------------------IKTEDSLS--HSPGQSGFLSYGSTFSTPPTGQAPYTYQ-MHG----------TSGIYQGT NGMTNSGGF--VSVHQ-DYPSYPSFTQSHYSQYYS-SSYNSPYVSTNNISSSPLS-----------TP-TYALQES---- ----SHNVASQSTESLPG-------------EYGSHNGSSTPAKDTESDRQHRGSDGKLRGRSKRSND---------PSP SMD-------------NEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHVDDVSSDDNGQDL---STYNFSADGFHSSAAG---ASLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGG ---LMGAPKRDTWLQLRSELEALTDLWLTQALKALNLIHSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGTVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Gallus_gallus-EYA2(ENSGALP_7168) -------------------------------------------------------------------------------- ---------------------------------MLDLVISPSLTVNKECPDRLKLNLTNIYATAPDDIEGNSKAAPQCPL HLYSTKHYPHIVTVQSFPTMATY-GQTQYSA---------GIQQAAAYTAYPPPAQPYGIPSYS---------------- --------------------IKTEDSLS--HSPGQSGFLSYGSSFSTPTAGQAPYTYQ-MHG----------TTGIYQGA NGLTNSAGF--SAVHQ-EYSSYPSFPQSQYSQYYS-SSYNSPYMSTNSISPSAIP-----------TS-TYSLQES---- ----SHNITSQSTESLS------------------GEYGTTPAKDIETDRHHRGSDGKVRARSKRSND---------PSP TAD-------------SEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHIDDVSSDDNGQDL---STYNFSADGFHSSAAS---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHALKALNLIHSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGTVFPIEN IYSATKTG-KESCFERIMQRFGRKAVHIAIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Taeniopygia_guttata-EYA2(ENSTGUP_5594) -------------------------------------------------------------------------------- ---------------------------------MLDLVISPSLTVNRECPDRLKLNLSHIYATAPDDIEGSSKAAPQCPL HLYTTKHYPHIVTVPSFPTMAAY-GQAQYST---------GIQQAAAYTAYPPPGQPYGIPSYS---------------- --------------------IKTEDSLS--HSPGQSGFLSYGSGFSAPAAGQAPYTYQ-MHG----------TTGIYQGA NGLTNSAGF--SAVHQ-EYSSYPSFPQSQYSQYYS-SSYSSPYVSANSISPSAIP-----------TS-TYSLQEP---- ----SHSISSQSTESLS------------------GEYSTTPAKDVETDRHHRGSDGKVRARSKRSND---------PSP TAD-------------SEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHIDDVSSDDNGQDL---STYNFSADGFHSSTAS---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGG ---LIGAPKRETWLQLRAELEALTDLWLTHALKALNLIHSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGTVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Xenopus_tropicalis-EYA2(ENSXETP_7517) -------------------------------------------------------------------------------- ------------------------------------------------------------------------------PL FYLCYRQYPHIVSPPSVPGMAAY-GQTQYSA---------GIQQTAAYSTYPPPGQSYGIPSYSNFFP------------ -------------------GIKTEDSLS--HSPGQSGFLTYGSSFSTPPPGQAPYTYQ-VHAQ-----SRTCPSGIYQGA NGLTNAGAF--GSVHQ-EYSSYPGFSQGQYPQYYS-SSYNSPYVPTNSISPTALS-----------TA-AYSIHES---- ----SHHVSNQSTESLSG-------------EYNTHNGPSTPIKDSENDRQQRGSDAKLRGRSKRSND---------PSP AVD-------------NEIERVFVWDLDETIIIFHSLLTGTFATRYG--KDTTTAVRVGLMMEEMIFNLADTHLFFNDLE ECDQIHIDDVSSDDNGQDL---STYNFSADGFHSSAAG---ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYSTYKNNVGG ---LIGAPKRETWLQLRAEMEALTDLWLTHALKALNLIHSR----PNCVNVLVTTTQLIP--AIAKVLLYGLGTVFPIEN IYSATKTG-KECCFERIMQRFGRKAVYVVIGDGVEEEQAAKKHN---MPFWRISCHADLEALRHALELEYL >Anolis_carolinensis-EYA2(ENSACAP_16399) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----NRHYPHIVTVPSFPTMATY-GQTQYSS---------GIQQTPAYTTYPPPGQPYGLPSYS---------------- --------------------IKTEDNLS--HSPGQSGFLSYGSGFSTTASGQAPYAYQ-MHGQ-----TEKCTSGIYQAP NGLTGSSGF--STVHQ-EYSSYPSFTQSQYSQYYS-SSYNSSYMSANSISPSAIP-----------TS-AYSLQES---- ----SHNINNQSTESLSGF-----------RFISIGEY-TTPIKDTETDRQHRGTDGKLRGRSKRSND---------PSP TAD-------------TEIERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTASVRIGLMMEEMIFNLADTHLFFNDLE DCDQIHIDDVSSDDNGQDL---STYNFSADGFHSSTAG---SNLCLGSGVHGGVDWMRKLAFRYRRVKELYDTYKNNVGG ---LIGAPKRETWLQLRTELEALTDLWLTHALKALDLIHSR----PNCVNVLVTTTQLIP--ALAKVLLYGLGTVFPIEN IYSATKTG-KESCFERIMQRFGRKAVYIVIGDGAEEEQGAKKHN---MPFWRISCHADLEALRHALELEYL >Danio_rerio-EYA2(ENSDARP_6502) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------MAAY-GQTQYSP---------ALQPAGPYTPYTHHTQGYSMTSYN---------------- --------------------IKTEDGLS--HSPGQSSLLGYTPNFSGTPPGQTLYSYS--HGG-----S--ISSGIFQGA NSITGSTPF--SPAQQ-DFSTYSSYSQSQYSPYYN-THYNSPYITASNITPSAIT-----------TAIPYQHTDH---- ----PAVSTNHSPESHTA-------------EYQAPTSPPTPGKDQDGAPPRRSADGKLRGR-KRASD---------PVP PLD-------------SDIERVFVWDLDETIIIFHSLLTGTFSTRFG--KDSGKAVSLGLWMEEMIFNLADSRLFFNDLE ECDQVHIDDVASDDNGQDL---STYNFGTDGFQTPAGG---GSLCLGSGVHGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGSPKREEWLQLRREMEVLTDLWLTQALKALALINSR----PNCVNVLVTTTQLIP--ALSKVLLYGLGGAFPIEN IYSATKTG-KESCFERVTQRFGRRAVYVVVGDGIEEETVAKKKN---MPFWRVTCRADLEALSHALELDYL >Oryzias_latipes-EYA2(ENSORLP_7802) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------SVMAAY-GQTQYSP---------ALQPAGPYAPYSHHTPGYSVPSYN---------------- --------------------IKTEDGLS--HSPGQTGLLGYT-NFSGTPPSQSLYSYSHTHGG-----G--ISSGIFQGT HAISGSTPF--NPTQQ-EFSSYSSYSQSQYSPYYNSHHYNSPYLAGSSISPPSIT-----------APLAYQHPDH---- ----PAMMPNHSPESHTG-------------EYHPPPSPPTPGKE-EGVPTRRGSDGKLRGR-KRVSD---------PTP PLD-------------SDIERVFIWDLDETIIIFHSLLTGTFSSRFG--KDSSKAVSLGLWMEEMIFNLADLRLFFNDLE ECDQVHIDDVASDDNGQDL---STYNFGSDGFQSPAGA---GSLCLGSGVHGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGSPKREEWLQLRREMEVLTDLWLTHALKALALITSR----PNCVNVLVTTTQLIP--ALSKVLLYGLGSAFPIEN IYSATKTG-KESCFERVTQRFGRRAVYVVIGDGAEEETVAKKKN---MPFWRVSCQADLEALSHALELDYL >Takifugu_rubripes-EYA2(ENSTRUP_34935) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------SNMAAY-GQTQYSP---------ALQPPGPYAPYAHHAQGYSVPSYN---------------- --------------------IKTEDGLS--HSPGQTGLLGYS-NFSGTPPSQSLYSYSHTHGG-----G--ISSGIFQGT HGISSSTPF--NPAQQ-EFSAYSSYSQSQYSPYYNSHHYNSPYLTSSNISPAAIA-----------APLAYQHPDP---- ----HVMLPNHSPESHAG-------------EYHPPPSPPTPGKE-EGVPARRGSDGKLRGR-KRVSD---------PAP PLD-------------SDIERVFIWDLDETIIIFHSLLTGTFSSRFG--KDSSKAVSLGLWMEEMIFNLADSRLFFNDLE ECDQVHIDDVASDDNGQDL---STYNFGSDGFQGPAGA---GSLCLSSGVHGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGSPKREEWLQLRREMEVLTDLWLTQALKALALINSR----PNCVNVLVTTTQLIP--ALSKVLLYGLGSAFPIEN IYSATKTG-KESCFERISQRFGRRAVYVVIGDGAEEEAVAKKKN---MPFWRVSCRADLEALSHALELDYL >Tetraodon_nigroviridis-EYA2(ENSTNIP_9... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------PTGRSNMAAY-GQTQYSP---------ALQPPGPYAPYAHHAQGYSMPSYN---------------- --------------------IKTEDGLS--HSPGQTGLLGYS-NFSGTPPSQSLYGYSHTHGG-----G--ISSGIFQGT HGISGSTPF--NAAQQ-EFSAYSSYSQSQYSPYYNSHHYNSPYLTSSNISPAAIT-----------APLAYQHPEP---- ----HVMLPNHSPESHTG-------------EYHPPPSPSTPGKE-EGIPARRGSDGKLRGR-KRVSD---------PAP PLD-------------SDIERVFIWDLDETIIIFHSLLTGTFSSRFG--KDSSKAVSLGLWMEEMIFNLADSRLFFNDLE ECDQVHIDDVASDDNGQDL---STYNFGSDGFQGPAGA---GSLCLNSGVHGGVDWMRKLAFRYRRVKEIYNTYKNNVGG ---LLGSPKREEWLQLRREMEVLTDLWLTQALKALALINAR----PNCVNVLVTTTQLIP--ALSKVLLYGLGSAFPIEN IYSATKTG-KESCFERISQRFGRRAVYVVIGDGAEEEAVAKKKN---MPFWRVSCRADLEALSHALELDYL >Homo_sapiens-EYA3(ENSP_362978) ------------------------------------------MEEEQDLPEQ--PVKKAKMQESGEQTISQVSN------ -----------------------------------PDVSDQKPETSS----LASNLPMSEEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETA--YPGQTQYQT----------LQQTQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQAS-------STNASLISTSS TIANIP-AAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSD--AESTT----------LAATTYQSEKP---- ----SVMAPAPAAQRLSSG----------DPSTSPSLSQTTPSKDTD-DQSRKNMTSKNRGK-RKADA----------TS SQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTVVIGSGLTMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYSFSTDGFSGSGGS---GSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGG ---LLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSR----KNCVNVLITTTQLVP--ALAKVLLYGLGEIFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHN---MPFWRITNHGDLVSLHQALELDFL >Macaca_mulatta-EYA3(ENSMMUP_17020) ------------------------------------------MEEEQDLPEQ--PVKKAKMQESGEQTISQVSN------ -----------------------------------PDVSDQKPETSS----LTSNLPISEEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETA--YPGQTQYQT----------LQQTQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQAS-------STNASLISTSS TIANIP-AAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNTD--AESTT----------LAATTYQSEKP---- ----SVMVPAPAAQRLSSG----------DPSTSPSLSQTTPNKDAD-DQSRKNMTSKNRGK-RKADA----------TS SQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTVVIGSGLTMEEMIFEVADTHLFFNDLE T------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Mus_musculus-EYA3(ENSMUSP_123045) ------------------------------------------MEEEQDLPEQ--PVKKAKMQEPREQTLSQVNN------ -----------------------------------PDASDEKPETSS----LASNLSMSEEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETT--YPGQTQYQT----------LQQSQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSSAHYSYPIQAS-------STNASLIPTSS AIANIP-AAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSD--AETTT----------LAATTYQTEKP---- ----SAMVPAPATQRLPS-----------DSSASPPLSQTTPNKDAD-DQARKNMTVKNRGK-RKADA----------SS SQD-------------SELE------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Rattus_norvegicus-EYA3(ENSRNOP_62689) ------------------------------------------MEEEQDLPER--PVKKAKMQEPGEQTLSQVNN------ -----------------------------------PDTSDQKPETAS----LASNLSMSEEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETT--YPGQTQYQT----------LQQSQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIPAS-------STNASLISTSS AIANIP-AAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSD--TENTA----------LAATTYQTEKP---- ----GAMGPAPATQRLPS-----------DSSTSPPLSQTTPNKDAD-DQARKNMTVKNRGK-RKADA----------SS SQD-------------SELE------------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Canis_familiaris-EYA3(ENSCAFP_17584) ------------------------------------------MEEEQDLPEQ--PVKKAKMQESGEQTLSQVSS------ -----------------------------------PEVSDQKPETSS----LASNLTMSEEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETA--YPGQTPYQT----------LQQSQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQAS-------STNASLISTSS TIANIP-AAAVSSISNQDYPTYTILGQSQYQTCYPSSSFGVTGQTNSD--AESTT----------LAAATYQAEKP---- ----SVMVPAPTAQRLSSG----------DPSTSPSLSQTTPNKEAD-EQSRKNMTGKNRGK-RKADA----------SS SQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTVVIGSGLTMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYSFSTDGFSGSGGG---GSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGE G--LLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSR----KNCVNVLITTTQLVP--ALAKVLLYGLGEIFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHN---MPFWRITNHGDLVSLHQALELDFL >Monodelphis_domestica-EYA3(ENSMODP_13... ------------------------------------------MEEEQDLPEQ--PVKKAKMQDSGEQALSQVNN------ -----------------------------------PEASDQKPETSS----LASNLTMSDEIMTCADYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETA--YSGQTQYQT----------LQQSQPYAVYPQATQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPAPSQHSVLTCTTGLTTGQPSPAHYSYPIQAS-------STNASLISSSS TIANIP-ASAVASISNQDYPTYTILGQSQYQACYPSSSFGVTGQSNSD--PENPT----------LAAATYQTEKP---- ----SVMVPAPAVQRLSSG----------DPSSSPSLSRSTPSKDTE-EQSRKNTPAKNRGK-RRADA----------AP AQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTVVIGSGLTMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYSFSTDGFSGSGGG---AGHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGG ---LLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSR----KNCVNVLITTTQLVP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHN---MPFWRITNHGDLVSLHQALELDFL >Ornithorhynchus_anatinus-EYA3(ENSOANP... ------------------------------------------MEEDRDLTEQQPTVKKAKMQESGEPALSQGTL------ -----------------------------------PDANEQKVEGPG----LASDVTMADGILTCTDYLPRPASDYSS-- QLYSAKPYTHILSVPVSETLTAYSGQTQYQA----------LPQSQPYTVYPQAAQSYGLPPFG---------------- ---------------ACHSWLR-RPWQVQTP-PTPAVVLHCRRGARKASKIPGHFA----AP-------SPNASLVSASS TATAAANVSAVASISSQDYPTYTILGQNQYQTCYPSPSFSLPAQTSSSSSAETAP----------LAAPVYQAGKP---- ----GGIAPTPANQRLSSG----------DPAASPSLARAAPSKEAE-EQARKNVAGKNRGK-RKADA----------TA SQD-------------NELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTVVIGSGLTMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYSFSTDGFSGSAGG---TGPGGAVGVQGGVDWMRKLAFRYRKVRETYDKPVWCHST G--LLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSR----KNCVNILITTTQLVPALALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHN---MPFWRVTNHSDLVSLHQALELDFL >Gallus_gallus-EYA3(ENSGALP_1125) ------------------------------------------MEEPQDLPEQ--PVKKAKMQESREQSLSHVSN------ -----------------------------------TEVSDQKAESSS----LGSNLPMSTEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETMSPYPGQTQYQA----------LQQSQPYTIYPQTTQTYGLPPF----------------- ------------------------------------------------------------AS-------TTNASPVSTSS TVVNIS-TSAVASISQQEYPTYTILGQSQYQTCYPSSGFGVITPADSN--AESTA----------LATATYPSEKP---- ----NAMVPTRTVQRHSSG----------DASTSPSLSRATASKESD-EQARKNIPGKNRGK-RKADT----------SS SQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTLVIGSGLSMEEMIFEVADTHLFFNDLE ECDQVHIEDVASDDNGQDL---SNYNFSTDGFSGSGSN---ANHSSSVGVQGGVDWMRKLAFRYRRVREIYDKYKTNVGG ---LLSPQKREALQRLRTDIEVLTDSWLETALKSLLLIQSR----KNCVNILITTTQLVP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEVAAKQHN---MPFWRITNHADLVSLHQALELDFL >Taeniopygia_guttata-EYA3(ENSTGUP_898) ------------------------------------------MEEPQDLPEQ--PVKKAKMQESREQSLSHVSS------ -----------------------------------TEVSDQKTESTN----LGSNLPMSSEIMTCTDYIPRSSNDYTS-- QMYSAKPYAHILSVPVSETMSPYPAQPQYQA----------LQQSQPYTIYPQTTQTYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSTSQHSVLTCTTGLTTSQPSPAHYSYSIEAS-------TTNASPVSTSS TVVNIS-TSAVASIS-QEYPTYTILGQSQYQSCYPSSGFGVVPPADSS--TESLA----------LATSTYPEEKP---- ----NTLVPARAVQRPSSG----------DASTSPLLPRATASKELD-EQARKNIPGKNRGK-RKADT----------SS SQD-------------SELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTLVIGSGLSMEEMIFEVADTHLFFNDLE ECDQVHIEDVASDDNGQDL---SNYNFSTDGFSGSGSN---ANHSSSVGVQG-VDWMRKLAFRYRRVREIYNKYKTNVGG ---LLSPQKREALQRLRTDIEVLTDSWLETALKSLLLIQSR----KNCENILITTTQLMP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEVAAKQHN---MPFWRITNHADLVSLHQALELDFL >Xenopus_tropicalis-EYA3(ENSXETP_28181) ------------------------------------------MEDGQDLTEQ--PVKKAKMQDSGEEGLSQVGN------ -----------------------------------NETGDRKAETSSN---MSSNHTIPSEILPCADYILR-ANDYTS-- QIYPAKPYTHILSVPVAETVAAYTGQTQYQT----------LQPSQPYTVYPQASPTYGLPPFG---------------- ---------------ALWPGIKSESGLIQTPSPP---AVLTSSGVSSSQSSPVLYSYPVQAS-------TTNASTMSSPS TIANIS-IPTVTNISNQDYPTYTILGQNQYPQCYPNQGF-PSAVASSN--AEANS----------VTPS-FPADKA---- ----ENPVPAQVSQRPLTD----------NAAA-------TGSKETE-EQNKKTVPVKNRGKGKKADA----------SS PQH-------------SDLERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPSLVVESGLAMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYSFTTDGFNGTAGN---RNHTTNAGVQGGMDWMRKLAFRYRKVIEVYEKYKNNVSG ---LLSPQRRDSLQRLRANIEALTDGWLGTALKCLLLIQSR----KNCVNVLITTTQLVP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVTRFGKKVTYVVIGDGRDEEMAAKQHN---MPFWRITNHNDLISLHQALELDFL >Anolis_carolinensis-EYA3(ENSACAP_17366) ------------------------------------------MEEAQDLAEQ--PMKKAKMQESGEQLLRQVNS------ -----------------------------------TDSSDQKPESSN----PGSNLSMSNEIMPCTDYISRSSNEYTS-- QMYSTKSYTHVLSVPVSETMASYSGQTQYQA----------LQQSQTYAVYPQTTQAYGLPPFG---------------- ---------------ALWPGMKPESGLIQTPSPSQHSVLTCTTGLTKSQSSPAHYSYPMQAP-------STNANSIATSS APVNIS-ASAITSISQQEYPTYTILGQSQYQPYYPSSAFGVITPADSS--TESAT----------LTPTTYPSEKP---- ----NAMVPTQTAQRHSSA----------GPDWDPSFPRATGSKDTD-EQYRKNVTGKNRGK-RKADP----------SS PQD-------------NELERVFLWDLDETIIIFHSLLTGSYAQKYG--KDPTLVIGSGLTMEEMIFEVADTHLFFNDLE ECDQVHVEDVASDDNGQDL---SNYNFSTDGFSGAGSN---ANHS-TTGVQGGVDWMRKLAFRYRKVREVYDKYKSNVAA ---LLSPEKKEALQRLREDIEMLTDSWLGTALKSLLLIQSR----KNCVNVLITTTQLVP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEMAAKQHN---MPFWRITNHADLVSLHQALELDFL >Danio_rerio-EYA3(ENSDARP_49839) ---------------------------------------MDESQEVPELPTKKARHDPEVSQEGDSRSVVANDSSDSPNR DESSTQS-----------------------NVNSYPPSSVTHLHSIPGAPDQSNQETISRSQGCVTENAYTHNAVTCKDL ATTTSTEYTSQMYQGSNTAVTAYASQVAFPS----------LGQSSMYSAFPQSGQTYGLPPFG---------------- ---------------AMWPGLKTE--LPEAPSVGQTGFLSFSSAYTSTQPNQIHYSYPSQGS-------CFTTSSVYTNI PPSTAVTTA---AGTHQEFTSYNSVGQNQFSQYY-VPPPSYMSAGLPSTDRDGAGV----------VAPGYPAIKT---- ----EGSASANLPNTTDASPG----VTLPTGVALPAGMALPTGARDQDEQNRKTPAGKAKGKAKKSDG----------SQ STD-------------NDLERVFLWDLDETIIIFHSLLTGSFAQKFG--KDPATVLNLGLQMEELIFELADTHLFFNDLE ECDQVHVDDVASDDNGQDL---SNYNFSSDGFSGPSAG---SGPGSTAAVQGGVEWMRKLAFRYRRLKEIYNGYKGNVGG ---LLSPMKRDLLLRLRSEIETVTDAWLSTALKSLLLIQS----RGRCMNVLVTTTQLVP--ALAKVLLYGLGDVFPIEN IYSATKIG-KESCFERIISRFGKKVTYVVIGDGRDEEFAAKQHN---MPFWRISSHGDLISLHQALELDFL >Oryzias_latipes-EYA3(ENSORLP_11778) ---------------------------------------MDEEQPAKKV---KVERDGGNSREQSHLGVGGSPPAALPSS EQAGSFG----------------------------LEAGEQKLSSTDGT-----AENQTCGDGGNSFPHAGSESAAASEY SQQGYQASSYENIPSLNPAVTSFSSQVAFPP----------LSQSSVYSGFPQSGQTYGLPPFG---------------- ---------------ALWPGIKTETGLPEAPSGGQPGFLSYSTAYTSTQPSALHYSYPSQGS-------SFTTSSVYSSM PSAVAVTAP-TTAASLQEFSSFSHLGQNQFSQFYTSPPTHEHSAG----------------------VAGYSSVKS---- ----EEASPADASPLES----------------VPAAAALPAGGRDQTELARRNSLGKAKGKNKKSET----------SP PAN-------------SDLERIFLWDLDETIIIFHSMLTGSYAQKFG--KDPAPVLNLGLQMEELIFELADTHLFFNDLE ECDQVHIEDVASDDTGQDL---SNYNFLADGFNGPSSG---ATSGAATGVQGGVEWMRKLAFRYRRLKEIYNSYKGNVGA ---LLSPVKRDLLLRLRSEIESITDAWLSTALKSLLLIQS----RGRCVNVLVTTTQLVP--ALAKVLLYGLGEVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEFAAKQHN---MPFWRISAHGDLTSLHQALELDFL >Takifugu_rubripes-EYA3(ENSTRUP_29555) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------PLTHILSCSPTVTSYPSQVVFPP----------LAQSTVYSTFPQTGQTYGLPPFG---------------- ---------------AMWPGIKTETGLPDAPSGGQPGFLSFSSTYTSAQPAHLHHSYPNQGS-------SFTTSSVYSSI LSATAATTTGTTTATQQEFS-YSSLGQNQFSQYYTALPPSYVPAGLPSSDDHSTGL----------GVAEYSAVKS---- ----EQAASAGLPPR---------------------GLAPPPGAREQDEVGRRNSVGKAKGKGRKCDS----------SP AAE-------------NDLERIFLWDLDETIIIFHSLLTGSYAQKFG--KDPATVLNLGLQMEELIFELADTHLFFNDLE ECDQVHIEDVASDDNGQEL---SNYNFLADGFNGASGG---GASGATTGVQGGVEWMRKLAFRYRRLKEIYNGYKGNVGG ---LLSPMKRELLLRLRSEIENVTDSWLTTALKSLLHIQS----RGKCMNVLVTTTQLVP--ALAKVLLYGLGDVFPIEN IYSATKIG-KESCFERIVSRFGKKVTYVVIGDGRDEEFAAKQHN---MPFWRISTHGDLVSLHQALELDFL >Tetraodon_nigroviridis-EYA3(ENSTNIP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------SSPAVTSYPGQEAFPP----------LAQSAVYSTFPQTGQTYGLPPFG---------------- ---------------AMWPGIKTESGLPGAPPGGQPGFLSFSSTFTSAPPAHLHYSYPNQGS-------SFTTSSVYSSI LSADRLFSV-----PTQEFSGYSSLGQNQFSQYYSALPPSYVPAGLPSSEDHGSGL----------GVAEYSAVKS---- ----EQAASAGLPPRDVSPP-----ETLPAGAALPAGAAPPTGARE-DEAGRRNCVGKAKGKGRKADS----------SP AAD-------------NDLERIFLWDLDETIIIFHSLLTGSYAQKFG--KDPATVLNLGLQMEELIFELADTHLFFNDLE ECDQVHIEDVASDDNGQEL---SNYNFLADGFNGAGGG---GASGAATGVQGGVEWMRKLAFRYRRLKEIYNGYKGNVGG ---LLSPLKRELLLRLRSEIETITDAWLSTALKSLLHIQSSSTTRGKCMNVLVTTTQLVP--ALAKVLLYGLGDVFPIEN IYSATKIGGKESCFERIVSRFGKKVTYVVIGDGRDEEFAAKQHN---MPFWRISAHGDLVSLHQALELDFL >Tetraodon_nigroviridis-EYA3(ENSTNIP_3... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------GS-------SFTTSSVYSSI L-------------PTQEFSGYSSLGQNQFSQYYSALPPSTR----PSSR---------------------SRRPR---- ----PACPPETLSPSDVSPP-----ETLPAGAALPAGVAPPTGARE-DEAGRRNCVGKAKGKGRKADS----------SP AAD-------------NDLERIFLWDLDETIIIFHSLLTGSYAQKFG--KDPATVLNLGLQMEELIFELADTHLFFNDLE ECDQVHIEDVASDDNGQEL---SNYNFLADGFNGAGGG---GASGAATGVQGGVEWMRKLAFRYRRLKEIYNGYKGNVGG ---LLSPLKRELLLRLRSEIETITDAWLSTALKSLLHIQSSSTTRGKCMNVLVTTTQLVP--ALAKVLLYGLGDVFPIEN IYSATKIGGKESCFERIVSRFGKKVTYVVIGDGRDEEFAAKQHN---MPFWRISAHGDLVSLHQALELDFL >Homo_sapiens-EYA4(ENSP_395916) --------------MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTT NGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATT---GDGALDTFTGSVITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SGSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTPS-----------STSTYQLQES---- ----LPGLTNQPGTDLHP------------GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTR----SNCINVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Macaca_mulatta-EYA4(ENSMMUP_9944) ----------------------------------------TRSMDMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTT NGTGGDNMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTTTT---GDGALDTFTGSVITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SGSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTPS-----------STSTYQLQES---- ----LPGLTNQP------------------AEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLN-ALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Mus_musculus-EYA4(ENSMUSP_90335) --------------MEDTQDLNEQSVKKTCPEADVSEPQNSRSMEMQDLASPHA-LVGGSDTPGSSKLDKSGLSSTSVTT NGTGV-----------------------SLLAVKTEPLHSSESTTTT---GDGALDTFTGSVITSSGYSPRSAQQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPAY----------------- ------------DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SSSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------STSTYQLQES---- ----LQGLTSQP------------------GEFDTVQSPSTPIKDLD-DRTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Rattus_norvegicus-EYA4(ENSRNOP_57892) -----------------------------------------RSMEMQDLASPHA-LVGGSDTPGSSKLDKSGLSSTSVTT NGTGV-----------------------SLLAVKTEPLHSSETTTTT---GDGALDTFTGSVITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPAY----------------- ------------DLGVMLPAIKTESGLPQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SGSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------STSTYQLQES---- ----LQGLTSQP------------------GEFDTVQSPSTPIKDLD-DRTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHATASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Canis_familiaris-EYA4(ENSCAFP_283) -----------------------------------------RSMEMQDLASPHP-LVGSGDTPGSSKLEKANLSSTSVTT NGTGGDNMTVLNTADWLLSCNTPSSATKSKVSTISELKNKSKTITLT---WNHPIDSFLNSIITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SSSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------STSTYQLQES---- ----LPGLTSQP------------------GEFDTVQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDLRCCSTYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Monodelphis_domestica-EYA4(ENSMODP_21... --------------------------------SSYAASYSNRSMEMQDLASPHT-LVGSSDTPGSSKLDKSNLSNTSVTT NGTGGDTMTVLNTADWLLSCNTPSSATMSLLAVKTEPMNNSETTTTT---GDGALDTFTGSVITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQTGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSNSTNF--SSSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------SSSTYQLQES---- ----LPGLTSQP------------------GDFDTVQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDRPEASWKEIHPEESPFYIAYLQLFCN-LR ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Ornithorhynchus_anatinus-EYA4(ENSOANP... -------------------------------------SCSNRSMEMQDLASPHS-LVGSSDTPGSSKLDKSNLSNTSVTT NGTGGDNMTVLNTADWLLSCSTASSATMSLLAVKTEPMNSSETTTTT---GDGALDTFTGSVITSSGYSPRSAHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSSLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFAP-SSTIYANN S-VSSSTNF--TSTQQ-EYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------SSSTYQLQES---- ----LPGLTSQP------------------GEFDTVQSPSTPIKDLD-ERTCRNSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDLRCCSTYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLLGPVKRDAWLQLRAEIEALTDSWLTNAHKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYGLGGVFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Gallus_gallus-EYA4(ENSGALP_22622) -------------------------------------------MEMQDLASPHN-LVGSSDAPGSSKLDKPNLSSTSVTT NGTG----------------------------VKTEPMNSNETTTTT---GDGSLDTFTGSVITSSGYSPRSAHQYSP-Q IYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFTP-SSTIYANN S-VSNSTNF--SSSQQ-DYPSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------SSSTYQLQES---- ----LPGLTSQPGTDLHS------------GEFDTVQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNIGE --GLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Taeniopygia_guttata-EYA4(ENSTGUP_11924) -------------------------------------------MEMQDLASPHN-LVGSSDASGSSKLDKSNLSSTSVTT NGTG----------------------------VKTEPMNNSETATTT---GDASLDTFTGSVITSSGYSPRSAHQYSP-Q IYPS-KPYPHILSTPAAQTMSAYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFTP-SSTIYSNN S-VSNSTNF--SSSQQ-DYSSYTAFGQNQYAQYYSASTYG-AYMTSNNTADGTSS-----------SS-TYQLQDS---- ----LPGLTSQPGTDLHS------------GEFDTVQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNIG- --GLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Xenopus_tropicalis-EYA4(ENSXETP_214) -------------------------------------------------------------------------------- ------------------------------------------------------------------------AHQYSP-Q LYPS-KPYPHILSTPAAQTMSAYGGQSQYS----------GMQQPTVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQSACLSYSPGFSPPQPGQTPYS-YQMPGTSTGSSFPP-SSSIYANN S-VSNSTNF--TNAQQ-DYPSYTAFGQNQYPQYYSASTYG-TYMTQNNTVDGTSS-----------SSSTYQLQDS---- ----LSGLTTQPG-----------------TDLQTVQSPSTPIKDLD-DRTCRTAGSKSRGRGRKNN----------PSP PPD-------------SDLED-FMWYIYTSVFSFVTLEIPSHGLEYIILKDSPTAVTLGLRMEEMIFNLADAHLFFNDLE ECDQVHVDDVSSDDNGQDL---SSYSFATDGFRAAASS---TTLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVG- --GLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTR----SNSVNVLVTTTQLIP--ALSKVLLYSLGGVFPIEN IYSATKVG-KESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNN---MPFWRISSHSDLLALHQALELEYL >Anolis_carolinensis-EYA4(ENSACAP_10268) --------------MEDTQDLNEQTVKKTCTDLDVSESQNSRSMEMQDLGSPHN-LVGSSETSGTSKLDKSNLSSTSVTT NGTSV-----------------------SLLAVKTEPMNSSESTTTTS--GDGSLDTFTGSVITSSGYSPRSSHQYST-Q LYPS-KPYPHILSTPAAQTMSGYAGQTQYS----------GMQQPAVYTAYSQTGQPYSLPTY----------------- ------------DLGVMLPGIKTESGLSQTQSPLQTGCLSYSPGFSTPQPGQTPYS-YQMP----GSSFTP-SSTIYANN S-VSNSTNF--SSSQQ-EYPSYTTFGQNQYPQYYSPSTYG-AYMTSNNTTDGTSS-----------SSSTYQLQDS---- ----LPGLTSQP------------------GEFDTVQSPSTPIKDLD-ERTCRSSGTKSRGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPVAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAASS---ANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNIG- --GLLGPAKRDAWLQLRAEIEALTDSWLTNALKSLSIISTR----SNCVNVLVTTTQLIP--ALAKVLLYSLGGAFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALELEYL >Danio_rerio-EYA4(ENSDARP_109988) --------------MENTQDLNEQSVKKSTTDSHAPDPVDNRALEMQELTDVQH-SVNSGSD-GTSKLDKNILSN-NITT NGTGGENMTILNTADWLLGCSSPPTAP-----IKSEPLNSSEAVSSA---GDSGLDTYTGSVISSSGFSPRPAHQYSP-P LYPS-KPYPHILTTPVAPPMSAYTGQSQFS----------SMQQSTVYTPYSQTTPPYGLSTY----------------- ------------DLGVMLPGIKTEGGLTQTQSTLQSG-LSYSPGFTTPQPGQTAYSPYQMP---AGSGFTT-SPGLYTSN N--SNPGNF--TTQQQ-EYPSYTTFGQNQYAQYYSTSSYG-SYMTSNSSLDGT-G-----------SVSTYQLQDP---- ------IMTGQAAD-LNP------------GEFEAGQSPSTPIKEME-DRACRGGGAKARGRGRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPLAVTLGLRMEEMIFNLADTHLFFNDLE ECDQVHIDDASSDDNGQDL---GTYSFATDGFHAAATS---ASLCLATGVRGGVDWMRKLAFRYRRVKELYCTYKNNVG- --GLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSR----SNCVNVLVTTTQLIP--ALAKVLLYSLGSAFPIEN IYSATKIG-KESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHN---MPFWRISSHSDLLALHQALEFEYL >Oryzias_latipes-EYA4(ENSORLP_20639) -------------CEVTYFPLVSLQVKKSHSESHVPDPSDVRSMEMQDLASPHN-RVGGGDS-TGSKLDKSNLESPSITS NGTGAQNLS-----------------------VKTEPLNSSDTVTTT---GDTALDTYAGSVITSSGYSPRSAHQYSP-P LYPS-KPYPHILSTPAAPSMPSYAGQPQFG----------SMQQSTVYTAYSQTGQPYGLSTY----------------- ------------DLGVMLPGIKTESGLTQSQSPLQTG-LSYSPGFTTPQPGQTAYSPYQMP----GSSFTP-SSGLYATN NSVSNPANY--TATQQ-DYPSYTTFGQNQYAQYYSASTYG-TYMTSN-SVDGT-G-----------STAAYQLQDP---- ----APAMTGQAA------------------DFDTVQSPSTPIKELD-DRACRSGGSKSRGRGRKNN----------PSP APD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPMAVTLGLRMEEMIFSLADTHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVG- --GLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSR----SNCVNVLVTTTQLIP--ALAKVLLYSLGSVFPIEN IYSATKIG-KESCFERIVSRFGTNITYVVIGDGKDEEHAASQHN---MPFWRISSHSDLLALHQALEFEYL >Takifugu_rubripes-EYA4(ENSTRUP_9464) --------------VNISSALVSLQVKKSHSESHVPDPSDARSMDMQDLASPHN-RVGGADS-TGSKLDKSNLGSPSITS NGLGGESMTVLNTADWLLGCSSPSPASASKDYVKTEPLNNSDTATTT---GDAVLDTYAGSVITSSGYSPRSAHQYSP-P LYPS-KPYPHILSTPAAS-QPTYAGQPQFS----------SMQQSSVYTAYSQTGQPYGLSTY----------------- ------------DLGVMLPGIKTEGGLSQSQSPLQTG-LSYSPSFSAPQPGQTAYSPYQMPG-SKGSSFNP-SSGLYATN NSVSNPANY--TTAQQ-DYPSYTTFGQNQYAQYYSASTYG-TYMTSN-SIDGT-G-----------STAAYQLQDPAA-- ----AAAMTGQAAE-LHP------------GDFDTVQSPSTPIKELD-ERACRSGGSKSRGRSRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPLAVTLGLRMEEMIFNLADSHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKELYTTYKNNVG- --GLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSR----SNCVNVLVTTTQLIP--ALAKVLLYSLGAVFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVVGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALEFEYL >Tetraodon_nigroviridis-EYA4(ENSTNIP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------LITSSGYSPRSAHQYSP-P LCPS-KPYPHILSTPAAPPMPSYAGQPQFS----------SMQQSSVYTAYSQTGQPYGLSTYSP--------------- ------------DLGVMLPGIKTESGLSQSQSPLQTG-LSYSPGFSTPQPGQTAYSPYQMP----GSSFTP-SSGLYATN NSVSNPANY--TAAPA?DYPSYTTFGQNQYAQYYSASTYG-TYMTSN-SVDGT-A-----------STAAYQLQDPSA-- ----AAAMTTQAAE-LHP------------GDFDTVQSPSTPIKELD-DRACRSGGSKSRGRSRKNN----------PSP PPD-------------SDLERVFVWDLDETIIVFHSLLTGSYAQKYG--KDPPLAVTLGLRMEEMIFNLADSHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYSFATDGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVG- --GLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSR----SNCVNVLVTTTQLIP--ALAKVLLYSLGSVFPIEN IYSATKIG-KESCFERIMQRFGRKVVYVVVGDGVEEEQAAKKHN---MPFWRISSHSDLLALHQALEFEYL >Drosophila_melanogaster-EYA1(FBpp0078... -----MLYNVPCYQNFSTLDYYKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLAS NGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFA QSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNP LDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPG------AAAAAAAYLTP SYAASGNNN--SQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDT HSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQP SPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYT--KDHSSLMTIAFRMEEMVFNMADTHFFFNEIE ECDQVHIDDVSSDDNGQDL---SAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGT ---LLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQR----ENCVNVLVTSTQLAP--ALAKVLLFGLGGIFNIEN IYSAHKIG-HETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMN---FPFWRISAHSDIRALYTALDMGFL >Ciona_intestinalis-EYA1(ENSCINP_17521) -----------------------------------------------------------MRDVTPIMTSDITEQTFVETS SKYNNEGAGF---------------------SPVQFQPQIMIPESSFAPPTAIPVDY-------QVTSQAEETSTQSQID YATMQSQFHYPRFPTQTG-------------------------NRAIKLEG-APQPAYSYVTQG---------------- -----------------------------FPAHAQYAIPGAGGGYG-------------------------YGGHASLT- ----TGHN-----MNTSQQEGYGGSG---YAHYYPTQGG--YFPSNTATSVMTSP-------------VTYQLQEPP--- ----PEHNIAGEP---------------------IKYTVDDLDRR---------KGGKAKTRNS----------RKNPSP GPD-------------AQLERVFVWDLDETIIIFHSLLTSSYAQRYG--KDASSTCALGLRMEELIFNLADNHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFSTDGFRSNTG-----NVCMATGVRGGVDWMRKLAFRYRRIKEMYETYAGNVQS ---LLPNHGRDAWAQLRSDLENVTDSWLTLAMKSLNIINQR----SNCVNVLATTTQLVP--ALAKLFLYGLGEVFNIEN VYSATKIG-KESCFERIIQRFGRNVTYVAIGDGRDEEQAAKVHN---MPFWRISSHSDLMALHHALEQDYL >Branchiostoma_floridae-EYA1(scaffold_... -----------MQCLYHAAPVYQVKKARHEELSDS---PANRLMDSQQLSSPGHQTGNGN-SPSSIANASYATNGTDTGQ GVIVTTGDSTVL-----------------TNSDWAMTGVTTQTTASVKS-EPITCDAPTSGTFTHGADFAGSTESRTMNS QGTSQNSTAYEGTAAQFAASQFPYGSPGRP---------YPHILPAPASQTGMPGYQQVVTGQQQ--------------- --------------------YMQPANPGYYNPQTRQPYLPGAYPPG---TYSTSAATYPTNS-------PATNTQAYAAQ QAVGKQTQS--GQEYTY-PPQFGQAGTYAHQYYTTPQGYSPFNTSSTTTLTAPS------------TTTTYQLQPMP--- --DLPTTGVVHED--------------------VTKVKS-------------------TPSRSKSR--------RKQPSP PPE-------------NDLERVFVWDLDETIIVFHSLLTGSYAQRFG--KDPQQAVALGLRMEEMIFNLADNHLFFNDLE ECDQVHIDDVSSDDNGQDL---STYNFATDGFHAAATS---ANLCLATGVRGGVDWMRKLAFRYRRIKEIYNSYKNNVGG ---MLGPAKREQWLQLRSEIEALTDSWLTIALKSLSIIHSR----SNTVNVLVTTTQLVP--ALAKCLLYGLGGVFPVEN IYSATKVG-KESCFERIVSRFGRKVTYVVVGDGRDEEQAAKQLQ---WPFWRISSHNDLAALHHALDLNLL >Strongylocentrotus_purpuratus-EYA1(XP... -------------MDHEDEDVRQVKRARTETEGDSNTPTPTRSLEIQQLSSPHSQVSNANGSSPQHANSPDSNNCSVTSN G---TDRSSSGQ-----------------SSLDMNLRQPKSEFPSQYYS-QAYPHILPTP--TAQGANFQ-PVGSQTQGT FG-SQSASSYP-YSTQTSPS--PYGLVGQA---------MSYGAKSLKSDP------ATLQGQGS--------------- --------------------YLSTYGSSSFTGSPQATQSPYYGMQG---TFTTAGYTYPSTSN------TTTNSQGFNS- ------THQ--GVEYGS-YTAYSQTG--FNQYYAS-QNYSPYSMSNSLSASTPLP-----------NTTTYQLAPLPS-- --DIENTFTTDAS--------------------IKLDDANGIGRGRQGQGQGPKNGNRTKSAGRSR--------RNNPSP PPE-------------DGLERVFVWDLDETIIIFHSLLTGSYATRFG--KDAPAAVSLGLRMEEMIFNLADMHLFFNDLE ECDQVHIDDVASDDNGQDL---SNYNFQTDGFHAAATS---ANLCLATGVRGGVDWMRKLAYRYRRIKEIYSSYKNNVGG ---LLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSR----SNCINVLVTTTQLVP--AVAKVLLYGLGGVFNIEN VYSATRVG-KESCFERIVARFGRKVTYVAIGDAKDEETAAKQLD---FPFWRVTSHSDLAALHHALDLGYL