>Danio_rerio-RAMP1(ENSDARP_60320) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MAS--------VSWRHA------LFVL-VAVNLLVLARACS-SHYGSAIEEFCMAKFKLDMEVLDQR QWCSWEDTVE-------------SYGELTNCTF---------------------LVALKMNCFWP--------------- ---NRM-----------------------VDEFFIRVHRHYFHD-CSLSG--------RLLHDPPN-------------- -------------------------------------------------------------------------------- ---RILGPFIVVPILVTLLMTALVVWRS---------------------------------------------------- -------------------------KRS-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Oryzias_latipes-RAMP1(ENSORLP_2951) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------IEV--------FGFLDL------SFDS-FAAQILPPASGCNRGAYEIKIDEFCQAKFRLDMMGLERS AWCSWPTTMK-------------IYEELTNCTH---------------------QVALKMDCFWP--------------- ---NAV-----------------------VDHFFMRVHTDYFSD-CALTG--------RLLHDPPI-------------- -------------------------------------------------------------------------------- ---SILAPFIAVPVLMTLLMTAAVVWRS---------------------------------------------------- -------------------------KRT-------EGML----------------------------------------- -------------------------------------------------------------------------- >Oryzias_latipes-RAMP1(ENSORLP_22680) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MGT--------ALLKHT------LLCLIVAVSQCVSVQGCG-SHYEFAIEEFCLAKFKLDMQMLDQR QWCSWEDTVE-------------LYSDLTNCTY---------------------IVAQGMNCYWP--------------- ---NRM-----------------------VDEFFIQVHRYYFHN-CSLSG--------RLLKDPPN-------------- -------------------------------------------------------------------------------- ---RILGPFIVVPILVTLLMTALVVWRS---------------------------------------------------- -------------------------KRS-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Takifugu_rubripes-RAMP1(ENSTRUP_37347) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------LAFSSH--------AKLLFL------LFYFQLLAHVLPLVSGCNRSLYERTIHDLCLANFRLDLGGLDPG LWCSWPDTMK-------------IYEDLTNCTH---------------------QVAHRVGCFWP--------------- ---NQM-----------------------VDRFFMQIHRSYFHN-CALTG--------RLIHDPPP-------------- -------------------------------------------------------------------------------- ---SILAPFIAVPVLVTLLMTALMVWRS---------------------------------------------------- -------------------------KRT-------EGVL----------------------------------------- -------------------------------------------------------------------------- >Takifugu_rubripes-RAMP1(ENSTRUP_19127) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------MISVIRKQNQPCQGLWRI------PLHLFTSVSQCVSASGCG-PQYELAIDEFCLAKFRLDMQELDQG HWCSWEDTVE-------------IYGELTNCTF---------------------LVALKVGCFWP--------------- ---NRL-----------------------VDDFFIRVHRHYFHD-CSLSG--------RLLRDPPN-------------- -------------------------------------------------------------------------------- ---GILGPFIAVPILVTLLMTALVVWRS---------------------------------------------------- -------------------------KRS-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Tetraodon_nigroviridis-RAMP1(ENSTNIP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------VSPVVS------FLSLI------RLFPVSAVSQCVSTLACG-PQYELAIDQFCLAKFRLDMQELDQK HWCSWEDTVEKSR----------IYGELTNCTF---------------------LVALKVGCFWP--------------- ---NRL-----------------------VDEFFIRVHRHYFHD-CSLSG--------RLLRDPPN-------------- -------------------------------------------------------------------------------- ---GILGPFIAVPVLVTLLMTALVVWRS---------------------------------------------------- -------------------------KRS-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Tetraodon_nigroviridis-RAMP1(ENSTNIP_(2) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MES--------PSLLTA------GFMALMAVSVLPLVSGCDRGFYEKMIQKLCLANFRSNLGGLDPG LWCSWPDTME-------------MYEDLTNCTF---------------------QVALGVGCFWP--------------- ---DHV-----------------------VDRFFMQIHQSYFHD-CALTG--------RLIHDPPP-------------- -------------------------------------------------------------------------------- ---SILAPFIAVPVLVTLLMTALVVWRS---------------------------------------------------- -------------------------KRT-------KGVL----------------------------------------- -------------------------------------------------------------------------- >Gasterosteus_aculeatus-RAMP1(ENSGACP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MGPPTG-----ATQRRQ------ALLWFIVVSQCVSALGCG-SHYEFGIEDLCLAKFRLDMHELGER HWCSWEDTVE-------------LYGRLTNCTN---------------------LVAFKLGCFWP--------------- ---NKL-----------------------VDDFFIRVHKHYFQD-CSLSG--------RLLKDPPN-------------- -------------------------------------------------------------------------------- ---RILGPFIVVPILVTLLMTGLVVWRS---------------------------------------------------- -------------------------KRS-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Gasterosteus_aculeatus-RAMP1(ENSGACP_(2) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------LEEL--------AMAAQR------ASLLMLLLAVLPSASGCNRGFYER-INDMCLVKFKLDMGGLDRG LWCSWPDTSE-------------IYEGLTNCTY---------------------QVASRMDCFWP--------------- ---NQM-----------------------VDRFFMEIHRDFFRD-CALTG--------RLLHEPPT-------------- -------------------------------------------------------------------------------- ---SVLAPFIAVPVLVTLLMTALVVWRS---------------------------------------------------- -------------------------KRT-------QGVL----------------------------------------- -------------------------------------------------------------------------- >Monodelphis_domestica-RAMP1(ENSMODP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------PP--------------------RGLWLCTFHCFILVTACPEADFGQLLNEFCLTKFKLEMDEIDKN LWCDWGQTVK-------------SYREVTNCTY---------------------LVAQKLDCYWP--------------- ---GPQ-----------------------VNDFFITIHRNYFHD-CPATG--------RVPKDPPS-------------- -------------------------------------------------------------------------------- ---NVLCPFIIAPILVTLLGTALVVYKS---------------------------------------------------- -------------------------QRN-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Bos_taurus-RAMP1(ENSBTAP_15322) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MAPG----LRGLRC---------RGLWLLLVTHLCLATACQHADHGTLLQEFCLPQFQAHMEAVGRT LWCDWGKTIR-------------SYRELSDCTR---------------------HVVQKLDCFWP--------------- ---NAE-----------------------VDKFFLVVHQRYFRN-CPVSG--------RALQDPPS-------------- -------------------------------------------------------------------------------- ---SILCPFIVVPILVTLLVTVLVVWRASAQRASCRPRSVCGGRGRAARSQKLQSRWEVGTEARPDQGFWSPNGRADPRA PPPPRKSPLLLRRAHPGMPA--RVVKHTRWPGKAAQGLGGSGHSCWSCWGWSELSPNNPHHSRVLPVARLWRSICD---- -------------------------------------------------------------------------- >Canis_familiaris-RAMP1(ENSCAFP_32174) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------APGSLSTWAGPPCGPWEGRGGDAGDTLVAVHHLLVATACQDADYGALLQDLCLARFKVSMEAIGKT LWCDWAKTIG-------------SYGELTDCTR---------------------HVADQLDCFWP--------------- ---NAA-----------------------VHKFFVAVHQRYFKN-CPASG--------RAVRDPPR-------------- -------------------------------------------------------------------------------- ---SILCPFIVVPILVTLLVTMLMVWRS---------------------------------------------------- -------------------------KRP-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Oryctolagus_cuniculus-RAMP1(ENSOCUP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------SYGALTHCTQ---------------------QVAAQLGCFWP--------------- ---NAE-----------------------VDKFFVAVHQHYFRS-CPVSG--------RAVHDPPS-------------- -------------------------------------------------------------------------------- ---SVLCPFIVVPIVVTLLVTALVVWRS---------------------------------------------------- -------------------------KRT-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Homo_sapiens-RAMP1(ENSP_254661) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------MARA----LCRLPR---------RGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGET LWCDWGRTIR-------------SYRELADCTW---------------------HMAEKLGCFWP--------------- ---NAE-----------------------VDRFFLAVHGRYFRS-CPISG--------RAVRDPPG-------------- -------------------------------------------------------------------------------- ---SILYPFIVVPITVTLLVTALVVWQS---------------------------------------------------- -------------------------KRT-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Macaca_mulatta-RAMP1(ENSMMUP_41196) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------SYRELADCTW---------------------HMAEKLGCFWP--------------- ---NAE-----------------------VDRFFLAVHGHYFRA-CPISG--------RAVRDPPG-------------- -------------------------------------------------------------------------------- ---SVLYPFIVVPITVTLLVTALVVWQS---------------------------------------------------- -------------------------KHT-------EGIV----------------------------------------- -------------------------------------------------------------------------- >Oryzias_latipes-RAMP3(ENSORLP_7549) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------CHVTPQRMSSLSKVAHSLSQFSIIFFLTATDTISVEPTSPWRRRICNESRLQWEVEVCGEDFKRNMAHIDPQ HWCNLTHFIS-------------EYHLFTLCTE---------------------NKSQNVNCYWP--------------- ---NPL-----------------------VESYIIRIHKHFFSN-CTLEQ--------VVWFDPPD-------------- -------------------------------------------------------------------------------- ---DTLAILILIPVFLTLAMIALVVWCS---------------------------------------------------- -------------------------KRS-------DILA----------------------------------------- -------------------------------------------------------------------------- >Takifugu_rubripes-RAMP3(ENSTRUP_10935) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------VLCSLPANDSFSLEPTAPW--RPCNESRLQWEVEVCGEDFKKEMDHIKLQ YWCNLTHFIS-------------EYYRFTQCTE---------------------VKSKMVHCYWP--------------- ---NPL-----------------------VESYIIRIHKHFFSN-CTNRQ--------VVYVDPPD-------------- -------------------------------------------------------------------------------- ---KTLTVLILVPVFLTLAMIALVVWCS---------------------------------------------------- -------------------------KRS-------DILA----------------------------------------- -------------------------------------------------------------------------- >Tetraodon_nigroviridis-RAMP3(ENSTNIP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------MDTNALTIVKL-LLLWILVDASLLSGLSANDSFVAEPTPAWPRRPCNESRLQWEVEVCGEVFKKDMDHIHPQ YWCNLTYFIG-------------EYHLFTLCTE---------------------AKSRLFHCYWP--------------- ---NPL-----------------------VESYIIRIHKHFFSN-CTNRQ--------VVFVDPPD-------------- -------------------------------------------------------------------------------- ---NTLTILILIPVFLTLAMIALVVWCS---------------------------------------------------- -------------------------KRS-------DILA----------------------------------------- -------------------------------------------------------------------------- >Gasterosteus_aculeatus-RAMP3(ENSGACP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------MVTSVLYLIRS-LSFFFAVNAWMMRGLSAADSLDIEPTAPRPKKACNESRLRWEVEVCGEVFKRDMGHIDPQ YWCNLTHFIS-------------EYHHFTRCTE---------------------LKADVVSCYWP--------------- ---NPL-----------------------VESYIIRIHKHFFSN-CSADH--------VVWVDPPD-------------- -------------------------------------------------------------------------------- ---DTLTILILIPVFLTLAMIALVVWCS---------------------------------------------------- -------------------------KRS-------DILA----------------------------------------- -------------------------------------------------------------------------- >Bos_taurus-RAMP3(ENSBTAP_27593) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MGTRALRRPYFFPLLLLLLLCGESPPVGGCNEKRMLAMLPRCGKTFAEKMKKVEVW KWCNLSEFIV-------------YYESFTNCTE---------------------VETNVVGCYWP--------------- ---NPL-----------------------AESFIASVHRQFFQN-CSVDR--------QDWEDPPD-------------- -------------------------------------------------------------------------------- ---EILIPLITVPVLLTIAMTGVVVWRS---------------------------------------------------- -------------------------KHT-------EQVL----------------------------------------- -------------------------------------------------------------------------- >Dasypus_novemcinctus-RAMP3(ENSDNOP_526) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------YYETFTTCTE---------------------AETNVVGCYWP--------------- ---NPL-----------------------AEGFITSVHRRFFSN-CTMDQ--------THWEDPPD-------------- -------------------------------------------------------------------------------- ---AILIPLVALPVLLTVAMAGLVVWCS---------------------------------------------------- -------------------------QRG-------HQLG----------------------------------------- -------------------------------------------------------------------------- >Monodelphis_domestica-RAMP3(ENSMODP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------GACQRTSGCNETLMLERLPACGKAFEEMMKKVDVK NWCNLTEFIT-------------YYDNFTSCTE---------------------LETNIVGCFWP--------------- ---NPL-----------------------TEGFITGVHRQFFSN-CTSDK--------VHWEDPPD-------------- -------------------------------------------------------------------------------- ---EILIPLILIPVLLTVGMASLVVWCS---------------------------------------------------- -------------------------KRN-------DVLV----------------------------------------- -------------------------------------------------------------------------- >Homo_sapiens-RAMP3(ENSP_418460) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------METGALRRPQLLP--LLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVW KWCNLSEFIV-------------YYESFTNCTE---------------------MEANVVGCYWP--------------- ---NPL-----------------------AQGFITGIHRQFFSN-CTVDR--------VHLEDPPD-------------- -------------------------------------------------------------------------------- ---EVLIPLIVIPVVLTVAMAGLVVWRS---------------------------------------------------- -------------------------KRT-------DTLLCGN-------------------------------------- -------------------------------------------------------------------------- >Macaca_mulatta-RAMP3(ENSMMUP_5103) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------METGARRRPQLLP--LLLLLCGGCPRAGGCNETGLLERLPLCGKAFADMMGKVDVW KWCNLSEFIV-------------YYESFTNCTE---------------------MEANIVGCYWP--------------- ---NPL-----------------------AQGFITGIHRQFFSN-CTMDK--------VHLEDPPD-------------- -------------------------------------------------------------------------------- ---EVLIPLIIIPVVLTVAMAGLVVWRS---------------------------------------------------- -------------------------KRT-------DTLL----------------------------------------- -------------------------------------------------------------------------- >Mus_musculus-RAMP3(ENSMUSP_47518) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MKTPAQR-LHLLP--LLLLLCGECAQVCGCNETGMLERLPRCGKAFADMMQKVAVW KWCNLSEFIV-------------YYESFTNCTE---------------------METNIMGCYWP--------------- ---NPL-----------------------AQSFITGIHRQFFSN-CTVDR--------THWEDPPD-------------- -------------------------------------------------------------------------------- ---EVLIPLIAVPVVLTVAMAGLVVWRS---------------------------------------------------- -------------------------KHT-------DRLL----------------------------------------- -------------------------------------------------------------------------- >Rattus_norvegicus-RAMP3(ENSRNOP_10866) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MATPAQR-LHLLP--LLLLLCGECAQVCGCNETGMLERLPRCGKAFAEMMQKVDVW KWCNLSEFIV-------------YYESFTNCTE---------------------METNIVGCYWP--------------- ---NPL-----------------------AQSFITGIHRQFFSN-CTVDR--------THWEDPPD-------------- -------------------------------------------------------------------------------- ---EVLIPLIAVPVLLTVAMAGLVVWRS---------------------------------------------------- -------------------------KRT-------DRLL----------------------------------------- -------------------------------------------------------------------------- >Canis_familiaris-RAMP3(ENSCAFP_4688) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------QHEGPLFRLCVMP--VAVPSPGGCPRVGGCNETRMLEKLPRCGKAFADMMHKVDVW KWCNLSEFIVW------------YYESFTNCTE---------------------VETNVVGCYWP--------------- ---NPL-----------------------AQGFITGVHRQFFAN-CTVDR--------THWEDPPD-------------- -------------------------------------------------------------------------------- ---EVLIPLIAVPVLLTVAMAGLVVWRS---------------------------------------------------- -------------------------KRP-------DQLL----------------------------------------- -------------------------------------------------------------------------- >Danio_rerio-RAMP2(ENSDARP110442) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MKTNVVLYQGLLLNALFLFSGQITQDNKTVFEETFQDQNLQYRRCDEQVLMFYGDYCWAVFSDNMSTIDEQ NWCVMEVVLR-------------SYSDLTECMD---------------------AASGIAGCFYP--------------- ---NHV-----------------------VEHLFMGIHQQYFSS-CNNEE--------D-LSDAPP-------------- -------------------------------------------------------------------------------- ---GVVLVATLLPIALIPFIVYIVVWKS---------------------------------------------------- ------------------------------------SLKY---------------------------------------- -------------------------------------------------------------------------- >Danio_rerio-RAMP2(ENSDARP_55236) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------MASLLTPTSKPTWNLLFWVCLCAMVSGLQTLVPNGQKH SVKMTVSTLPTVQTTAYTRADPVHGNGGTIGCANKG-GCEVYCSICVNITAQ---ECYEILVNHWCNYHFVLAMDSMNST DWCSLEKVKS-------------AYNNFTMCTE---------------------TVADCLLVPWP--------------- ---NRF-----------------------VEQKFVDIHATYFHD-CPTEA----------LRDPPP-------------- -------------------------------------------------------------------------------- ---SIILALVMTPICLIPVMVVLVVFKT---------------------------------------------------- -------------------------KNG-------DRRS----------------------------------------- -------------------------------------------------------------------------- >Oryzias_latipes-RAMP2(ENSORLP_5336) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------MKGALAFIG-------VFLSFLS--------------- --VLNFGFIP-------------------ATCGSGP-YCESLCSICEDIFSGPSVECLSALFHHFCMPKFNNAMDLLNTT DWCVWGNVNS-------------LYSNLSICTE---------------------EISDCLQIPWP--------------- ---NPL-----------------------VEQIFVDIHSTYFKE-CPTEE----------FSDPPP-------------- -------------------------------------------------------------------------------- ---ATVFALVITPICLIPIMVSLVVLKT---------------------------------------------------- -------------------------KNG-------DGSS----------------------------------------- -------------------------------------------------------------------------- >Takifugu_rubripes-RAMP2(ENSTRUP_38554) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------MGKSLVLCWG-------FWILLGWGCETTVCSVDDKSTV QPVTSTAYLSTTPGIANHTNGQMMP----FACGSKSHICPEYCSTCY-YFAGPTIHCISILLHNECLKIFEDEMVSRNRD DWCNWGNVSG-------------LYSNLSLCTE---------------------KVFDCLLIPWP--------------- ---NPF-----------------------VEAIFVDIHTKFFRD-CPTEE----------LNDPPP-------------- -------------------------------------------------------------------------------- ---AIVFALVITPICLIPVMVSLVVLKT---------------------------------------------------- -------------------------KNG-------DGSS----------------------------------------- -------------------------------------------------------------------------- >Gasterosteus_aculeatus-RAMP2(ENSGACP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------KSNIQFFS-------YLISLLAGCSTVVCLVNEKITA PPATPTGYFSTVTEVATPTNSELLLCRKNAACGNNSDTCGIYCRICDTHYHGPTMDCLSTLLQIQCITKFYDAMASLNST EWCTWSNVGG-------------LYSNLSLCTE---------------------EISDCLMIPWP--------------- ---NPL-----------------------VEQTFVEIHSSHFKD-CPSQE----------LSDPPP-------------- -------------------------------------------------------------------------------- ---VIVFALVMTPICLIPVMVSLVVLKT---------------------------------------------------- -------------------------KNG-------DGRP----------------------------------------- -------------------------------------------------------------------------- >Monodelphis_domestica-RAMP2(ENSMODP_1... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------MASIETRCSGCPHLPA TPARLRSPLW-------LLLLLCSILNAQGSGAQTVPNGSFASVPIV-----MTSEQNYELTARQCWFSYEDHMRNISTE HWCEWDMISR-------------PYSDLQYCLE---------------------KMAEYLKLGFP--------------- ---NSL-----------------------AEQIIFHSHQMYFAN-CSLERR-------PLFFDPPE-------------- -------------------------------------------------------------------------------- ---EVLLALIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDS-------EVQT----------------------------------------- -------------------------------------------------------------------------- >Gallus_gallus-RAMP2(ENSGALP_40567) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------EIYTNLTHYCWESFVKVMQNVTGA QLCEWKVISR-------------PYSSLQKCLE---------------------DHADLLNYSYP--------------- ---NAL-----------------------AESYIFQSHHHYFQN-CSAGS--------QAYFDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVIWRS---------------------------------------------------- -------------------------KDG-------KAQP----------------------------------------- -------------------------------------------------------------------------- >Taeniopygia_guttata-RAMP2(ENSTGUP_2853) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------LTERNYTDMTEECWKYFVSLMGNVMTS ELCEWKVISR-------------PYSALQRCLE---------------------DWAESFNYSYP--------------- ---NAL-----------------------AEQYIFQSHHRYFHN-CTLEQ--------PVYFDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVIWRS---------------------------------------------------- -------------------------KDG-------KAQA----------------------------------------- -------------------------------------------------------------------------- >Canis_familiaris-RAMP2(ENSCAFP_21815) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MASLRAERAASGPRLPA TRAGRPAALR-------LLLLLGAVLKPQESLAQLLPTE--GSLKLE----GNK-MADYETSVQFCWQSYKEQMDSIP-K DWCDWAMISR-------------PYSDLQYCLE---------------------HFAEAFGLGFP--------------- ---NPW-----------------------AEEVIFETHQIHFAN-CSLVQ--------PTLSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDN-------EAQA----------------------------------------- -------------------------------------------------------------------------- >Homo_sapiens-RAMP2(ENSP_400664) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MASLRVER-AGGPRLPR TRVGRPAALR-------LLLLLGAVLNPHEALAQPLPTT--GTPGSEASVPTGGTVKNYETAVQFCWNHYKDQMDPIE-K DWCDWAMISR-------------PYSTLRDCLE---------------------HFAELFDLGFP--------------- ---NPL-----------------------AERIIFETHQIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLITLVVWRS---------------------------------------------------- -------------------------KDS-------EAQA----------------------------------------- -------------------------------------------------------------------------- >Macaca_mulatta-RAMP2(ENSMMUP_2868) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------AVLKPHEALAQPLPTT--GTTGSE-----GVTVKNYETAVQCCWNHYKDQMDSIE-K DWCDWAMISR-------------PYSTLRECLE---------------------HFAELFDLGFP--------------- ---NPL-----------------------AERIIFETHQIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLITLVVWRS---------------------------------------------------- -------------------------KDS-------EAQA----------------------------------------- -------------------------------------------------------------------------- >Mus_musculus-RAMP2(ENSMUSP_122072) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MAPLRVERAPGGSRLGV TRAQRPTALCLPPLLLLLLLLLGAVSASPESLNQSLPESQNQSHPTEDSLVSKGKMEDYETHVLPCWYEYKSCMDSV--K DWCNWTLISR-------------HYSDLQNCLE---------------------YNADKFGLGFP--------------- ---NPL-----------------------AENIILEAHLIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDS-------DAQA----------------------------------------- -------------------------------------------------------------------------- >Rattus_norvegicus-RAMP2(ENSRNOP_27698) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MAPLRVERAPGGSQLAV TSAQRPAALRLPPLLLLLLLLLLGARDHPASANRPSPESLNQSHPTEDSLLSKGKMEDYETNVLPCWYYYKTSMDSV--K DWCNWTLISR-------------YYSNLRYCLE---------------------YEADKFGLGFP--------------- ---NPL-----------------------AESIILEAHLIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDG-------DAQA----------------------------------------- -------------------------------------------------------------------------- >Oryctolagus_cuniculus-RAMP2(ENSOCUP_2... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MASLRAERAAGGPRLP- -------ALR-------LLLLLLAVLKPQESLAQTLPTP--GSLEPE----GRTGEENYETNVLLCWNDYKVYMDSIE-K DWCDWAVISR-------------PYSELRDCLE---------------------QNAEEFGLGFP--------------- ---NPW-----------------------AERIIFETHQIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDS-------EAQG----------------------------------------- -------------------------------------------------------------------------- >Bos_taurus-RAMP2(ENSBTAP_34674) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------MASLRAEHAVGGSWLPA TRSGRPAALR-------LLLLLGAVLKPQESLAQLLPTP--DSSKSE----GKTVLETYGTNVLQCWHDYKVQMDSIK-K DWCDWALISR-------------PYSFLRDCLE---------------------KGAEEFGLGFP--------------- ---NPW-----------------------AEEIIFETHNIHFAN-CSLVQ--------PTFSDPPE-------------- -------------------------------------------------------------------------------- ---DVLLAMIIAPICLIPFLVTLVVWRS---------------------------------------------------- -------------------------KDS-------EAQT----------------------------------------- -------------------------------------------------------------------------- >Anopheles_gambiae-RAMP2(XP_318843) MLKLLIKCTIGALFALQSIHCEADPQLNLPPLAPPGLEGRRPVTFPNGEASPTRVPLGVDGVVSGDGSSVHDRSRSERFG PPYDGDDDEEDERPNYPAQQPEGRANDYDRRDRQDSPYSYNDRNRYGGDRGYDRNQNRERYPGDRSPNPYVSDVDNPLLY RDGGDRNRNRYVSDVENPLLYRDRTPYNPSRDYDDRNRYNPNARPYNPNDPSFGGRNPPDPNYRGPGQRDPNYRDQGFRE PGQRFPGDDRTRYPDDPNYPYRSPEEERFRIENERRFRAETEKLRAFLTEIDRKSSLECSLNVAAQWNFETNINDATQVE ALAAQQRYNDFQRLLWDQMRRIDQTKIFDDKLYRQVRLMSIIGPSALPPDQLDRYNRIVNDMLAIFNGATICAYEQPFEC GLRLQPHLKDVSEQSIMAKSRDWNELQYTWLEWRRKSGRNMRDLFEQLVDLTNDAGRVNNFTDAAAYWTFPYESRNFREE MEQVWREILP-------------LYEMIHAYVRRKLREFYGPDKINKNAPLPDHILGDMYGQSWQ--------------- ---NILDIVIPYPGRSFLEVTPEMQKQGYNPLVMFQIAEEFFVS-MNMSAMPPDFWASSIVTQPPDRPILCQPSSWDFCT GKDYRVKMCTQVTHKDFITVHHELAHIQYFLNYRNNPKVFRDGANPGFHEAIGDAISLSVASPKHLQNLGLVQKSVDDTA HDINFLFSLAMEKVVFLPFALALEAWRYDVFSKRVRKEQYNCHWWLLREEYGGVKPPVLRSELDFDPGAKYHVAANIPYI KYFFSNVLQFQIYRALCTASGQYVPQDPSKPLHKCDIYRQPAAGNILKKLMERGTSQPWQQVLQEVIGEGRLDGSALREF FRPLEEWLRNENLRNNEYVGWIYDGDYCKHSIETANLQVFGGFYNVAVEVQLTSWLMLMLSSWLVVMRTFAIVG >Drosophila_melanogaster-RAMP2(FBpp_87... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------MHGYRTYNMESHHAHHDASPVDQKPLVVDLLATQY GKPQTPPPSPNECLSSPDNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIK VWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAAS------------------ILQAAANSVGMPYPPYAPAAAAAAAAAAA VATNPMMATGMPPMG-----------MPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAG----------- -------------------------------------------------------------PHMHHPHMMGSSATGSSYS AGAAGLLGALPSATCYTGLGVGVPKTQTPP-------------------------------------------------- ----------------------LDLQSSSSP--HSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTSPLPAPGL LMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA--------------------------------------