>Danio_rerio_(Zebrafish)SOCS1b(Chromosome_1:_8038708-8042130) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------MSGLQFRMVHHNDN----------------GHTNA PPKS---------------------------------------------------------------------------- ---AEPPKPCSVPP----------------THFHPFRDQQECNLIKQAVVYLTH-------------------------- ---SGFYWGPLDVDEAHARLANLPLGTFLI---RDSMQANVFFTLSYR---APEGPTSVRVLL-----KN-ESFSLAG-- ---------SKHT-FSCIFG--LLGYYIAS-----------------------------------------------PKK SLSRP--------YRGD-VPQTLQELARRAVVQSF----GKDSIPHLP-VSKKLKEFIWLYPFSI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Danio_rerio_(Zebrafish)SOCS3b(Chromosome_3:_58237025-58239849) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MITHSKLD-------------------------------------------------------------------NAM SSGLFDASMRLPF-----------------YHFKTFSSKVQFQLVQHTIRMLQE-------------------------- ---SGFYWGAISGKEANHLLSSEPSGTFLV---RDSSDNRHFFTLSVK---TESGTKNLRVQC-----DN-KSFFLQT-- ------DSKSMQSVPRFDCVLRLVQHYMPRSALSIG---------------------------IPRSSYYIYTGGEKIPL ELLRP--------LQC--SMSSLQHLCRKTVNGH-T----DVSSKREH-LPQQLKDFLQEYDAPI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Takifugu_rubripes_(Fugu)SOCS1b(scaffold_40:_493007-493658) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------THLRPFSSLAQYKLVRTTYVQLLH-------------------------- ---SDYYWRSMTMEEAHRILASAQLGTFLI---RDSCQPDIFFTLSYQ---SDEGPISIRIQL-----ND-LLFSLCG-- ---------SQRT-FTSLFS--LLAYYSSS-----------------------------------------------SCK -LTTP--------YRKQ-RPELLKQMCRRALIRTY----RAEDL-LLPGLS-KIKDYVLAYPYCI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Takifugu_rubripes_(Fugu)SOCS2b(scaffold_87:_457888-458553) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------PPAP-----------------PAAWGPSEDYRSITATFRYLET-------------------------- ---SGWYWGPTSVSDAQEALLRKSEGTFLM---RDSNHPKHMLTLSVK---TCCGPTSVRIEY-----SR-GSFWLDS-- ------IAAGQLRTQTFPDVVSLVQHYMTLGHVPQSHTHSDMYQR--------AKPDPSGDAA----------RGCDVPL KLMFP--------LHKPGGFPSLRHLTRLAINRHAS------CPDQLP-LPKLLLRYLQDYPFHI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Tetraodon_nigroviridis_(Tetraodon)SOCS1b(Chromosome_18:_9114794-9115414) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------THLRAFSSLAEYKLVRKTYVQLLH-------------------------- ---SDYYWRSMTMEEAHRALAHAQLGAFLI---RDSGQPDVFFTLSYQ---SEDGPTSIRIQL-----NN-LLFSLCG-- ---------SHRT-FASLFS--LLAYYTRS-----------------------------------------------SCK -LTTP--------YRQQ-RPERLKQMCRRALIRTH----GAENINTIPGLS-KLKDYVHAYPYCI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Tetraodon_nigroviridis_(Tetraodon)CISHb(Chromosome_11:_6552636-6554271) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MQDSYDFHQFK GCHQSAMVARA------------------------------------------------------------------MAL FPHQEAGVLCCPNAP-----------------PPAWGPSEDHRSITTTFQYLET-------------------------- ---SGWYWGPTSVSEAQEALMKKPEGTFLM---RDSSHPKHMLTLSVQ---TCCGPTSVRVDY-----SR-GSFWLDS-- ------IAAGQPCTQTFPDVLSLVQFYASSGPVPQSQTPSAAHPK--------VKPEPAPDLA----------QGSNVAL KLMHP--------LHKPGAFPSLRHLTRLTINRHAS------CPRPAA-AAKASAGLPAGLPVSGMRGSVVGAGVAP--- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Oryzias_latipes_(Medaka)SOCS1b(Chromosome_1:_25168617-25173035) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------MVRDGLNRTAIQCQKQNKPAE---------IEGQSQA PEEGTSPEQSE----------------------------------------------------------NPDRQLEPLWW NQPVEEPIPWSQPVTGAE--------ADFFTHLRPFSSQEAYKLVRHTYQQLQH-------------------------- ---SGFYWGPMTMEEAHEKLSHAPIGTFLI---RDSGQPDVFFTLSYQ---SEDGPTSVRIIL-----EN-LLFNLYG-- ---------SLRT-FSSLFA--LLTYYTSS-----------------------------------------------SCK -LTEP--------YRKQ-RPERLKQMCRRAVIRAY----GSECTSTLPGLSVQMKAYVRAYPHCI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Oryzias_latipes_(Medaka)SOCS2b(ultracontig62:_278438-278929) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----WYWGSISAGEAKEALLTKPEGTFLL---RDSSHPQFMLALSVK---TRCGPTSVRIDY-----NR-GCFWLDS-- ------ISRGAPHLKTFSDVLSLIQHYTVSGQTSQDLAS----FK--------TKADPSQHAA----------KDAGVPL RLVRP--------LHRREGFPSLQHLARLTINKQTN------CPDQLP-LPKPLLDFLQNYPFII--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Branchiostoma_floridae_(Amphioxus)SOCS4XP_002604536 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------EVA-QKLTPR-------------------------------------------------------------- ---------------------------------RIHTQIDYIHCLVPDMVTIVN-------------------------- ---QPYYWGVMDRYEAEDVLEGKPEGTFLL---RDSAQEDFLFSVSFR---RYGRTLHARIEQ-----WN-HLFSFDV-- ---------HDPAVYAAPTVCQLLEHYKNPDCCMF------------------------------------------FEP MLTTP--------LPRP-FTFPLQALCRSVICKFT----SYDGINSLR-LPGSLKDYLKVYHYKQRVRVRRFEMDKQPAI KITTV--------------------------------------------------------------------------- ----------------------------------------------------------------------- >Branchiostoma_floridae_(Amphioxus)SOCS5XP_002605939 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKRLTLKNLKR SLHHQSKQGGGEGGEGIEEAYNSDSETACREEDSDESAEVPGRRLRRAGTLPYPSRRRREREGFMSTIRH---------- ---RLKIGKGSQD----QQNTTEEVKDE------------------------------EREDAEVVEEETVTPRRPTRSK SMRVRK-------------KESATTVALRPANSEENLSQRKDSQYWTRKLHEKNRKDLPP-------------------- ------------------------------------------------------APHDGDENGEITMDI----------- ----------------------------------------CHKKVERKDSSDSRSSKSSKSRNSPFS------------- --------------VSSINCTQEKPISSEKSRLKALRSFLTLPRRGSKKKGSKEKEEPDSPDTISSN------------- -------GVSPRALPPCPSLTESHDIFNGASSTVPRPRNG------------------------------NNGS-SYEPY DDEDNERKIASYEQVGGR--------------------THVNHSLTEELRKLVR-------------------------- ---HGWYWGPISRAEAEEKLAHLSNGSFLV---RDSSDDRYLLSLSFR---SYDRTFHTRIEHC----N--GIFSFYSQ- ----------VESEG-HKSIVDLIEHSMRES-QSAVFCYSRSRTPGA----------------------------PSFPV RLTNP--------VSRFTQVRTLQYLCRFVIR-QYTRI---DHIQLLP-LPTKIREYLQECHY----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Branchiostoma_floridae_(Amphioxus)SOCS7XP_002598571 ------------MAESANIRLVDRVKRKLRFTNRRRDHDIRQLDTETAKTYMARYRSTASNSHIQETVLQNGAGTTTSPT EKSESVSRAPPIKEVEKGTAALKIGEFKDDSSTNARSIPSPHMNGNVRQRGIVDLPSDENVNEIAIIGLEQTKTVPYEHA RLCKDTIPSGLLPTDVEAYLVERQGHKNHICNGNGMLAGPKPDRMNTAQDVLISGGTDGLQQASCQPCKKDTCETYKEKV LANGDMQGEGFPVPAEKLSESQRGQSETTPCHNGRKGLEVPGRKTSITDVMPSRVDDRNANAALPVRTEPLKNARKASAA ESAFTGGNRKDSLSDMESISSEADASGAKEAEVQQDSEVIREEQLQVKQPMSPCMPVQVDEGYRSDCSPT---------- ---MTAKQCAEIKDVESNPSANVACACGSSKNLDQGQPQNGRRCPNPPSEEIPNAAMTEKSDSKEAGSTPTKTFNSADCQ SGSCNKENRLPEHPKCEGAPPCVANGTASQTPCAEATNEPKIDLGARPKEKKPGDCVDRSKLSPSFKHRSVSDGHVCISR RYNDDGSPPPLPPRDPSLFQRLLNSRGPPVADVEEDEFPTHEFLPEMDHPPVFDEASLSLVERETFQRDLLTNAIQHRRS LEFVTEVNRDSTVLVGGR----------------------RRESCGENSPNGVDSNRQVPPSSPNSLMPPPLSVGHPQAG SSRPGDYHDVVLPARNARPTSLYQNTGSNYVNTGNYAGKMPESPGPRSPKSPKILQRDYEDSRNQEANFKKRMSVWLETC KKNLDPRKRHSASDLKLANRPLPDLPPVEAMKPPPNPAVL------------------------------PG--LRENPP EVDPLPENSVFLKNRPKYGRV----PSTTGEKEDLPPVEGSPREFARSLKELER-------------------------- ---CGWYWGPMNWDDAETKLAGKPDGSFLV---RDSSDDRYILSLSFR---ARGGTHHTRIEHS----K--GVFSFWSQ- ----------PKSHGCSPSIVEFIETAMLHSNTGKFQYYLRARALGS----------------------------PPVPV LLLKP--------ISRFENLKTLQHICRFVIR-KQVRI---DHIDLLP-LPKGLKVYLTDCQYYDIEEETFFDERKRKEE QKSG--DDSDEDEEDQREGLY----------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS1(Chromosome_14:_9162499-9163122) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------MVAHSKVSADNAVA---------------ADPR CLLDPPARDRS----------------------------------------------------------QARG----YRG TG---RP----GAAQA-----------PSSTHFRTFRSQADFSSITRASSLLDA-------------------------- ---CGFYWGPLTVSAAHEKLKSEPEGTFLI---RDSTQKNCFFAISVK---TATGPTSIRINF-----QT-GRFSLDG-- ---------SKET-FDCLFK--LLEHYLSS-----------------------------------------------PRK VLVTP--------LRKV-RVQPLQELCRKSIVKTF----GRENLNQIP-LNPVLKDYLKSFPFQI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS2(Chromosome_1:_46783618-46785293) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------MRRK------------------------------------------------------------------ANY FLW--------------------------------QIKLYDACRTP-ACEQLWKWVSADPSGEERAVTRTAGSKSISAFS PPLPGWYWGNMSVAEAKERLQDAPEGTFLV---RDSSHSEYLLTISVK---TSAGPTNLRIEY-----QD-GKFRLDS-- ------ITCVRSRLKQFNSVVHLIEYYVLMCKDR---TETP--------------------------------SNGTVHL YLNKP--------LYT--SAPSLQHRCRITINKCTN------QIWELP-LPTRLKEYLKEYRYQV--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS3(Chromosome_18:_9788132-9790179) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MVTHSKFP-------------------------------------------------------------------AAG MSRPLDTSLRLK----------------------TFSSKSEYQLVVNTVRKLQE-------------------------- ---SGFYWSTVTGGEANVLLSAEPAGTFLI---RDSSDQRHFFTLSVK---TESGTKNLRIQC-----EG-GSFSLQS-- ------DPRSSQPVPRFDCVLKLVHHYMP-PTPCAGPEQPGGALH-------------------PKRTYYIYSGGEKIPL VLSRP--------LSS--SVSTLQHLCRKTVNGH-L----DSYEKMTQ-LPAPIKEFLDQYDAPL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS4(Chromosome_5:_58880897-58882207) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------MAENKDSNTKNTDVRPKSSRSR-------- -----------------------------------------------SAD------------------------------ -RKDGY----VWSGKK-LSWSKKTERCSDAETANAAGRSGPNLRSQERKYSCSSIELDLDRSCG---------------- -------HRFLGRSLK--------------------------------------QKLQDAVGQCFPIKN----------- ---------------------------------------------CTSRHASGLQSKRKIHISELMLDKCP--------- ---------FPPRSELAFRWHLIKRHTAPVNQ----KAE----DWIIADLSQNEEKEEDLR-------DNE-----VESD PPSAPSPSSDL--TDGIPSRRDSRSELVAGKVVRSSKD---------------------------DSDMDSDDE-VITLC TSSRKRNKPKWETDDEL---------LRMETPPKYHTQIDYVHCLVPDLLQINN-------------------------- ---NPCYWGVMDKYAAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYSRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSPDITGLLEHYKDPSSCMF------------------------------------------FEP LLSTP--------LNRT-FPFSLQHICRTVICNCT----TYDGIDALP-IPPSVKLYLKEYHYKSKVRVLRIDVPEQQS- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS5(Chromosome_3:_28036388-28037995) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------MDKVGK MWNNFKYRCQNLFSHEGGS-QNENVVVNSSSCSSAKDRTVQITGLAQQQPSSPLRENIALQLGLSPSKNSVR-------- -----------------------------------------------RNQNCVTEIPQIVEISIEKEN-DSCVTT-GARL ARRDSYSRHAPWGGKKKHSCSTKTQSSLDTE--KRFGRTRSGLQRRERRYGVSSVHDMDAASN----------------- -------RTVGSRSLR--------------------------------------QRLQDTVGLCFPMRT----------- ---------------------------------------------YSKQSKPLFSNKRKIHLSELMLEKCP--------- ---------FPAGSDLAQKWHLIKQHTAPVSP----HST--FFDTFDPSLVSTEDEEDRLRERRRLSIEEG-----VDPP PNAQIHTFEAT-AQVNPLYKLGPKLAPGMTELTGDKNA-------------------------TPPGNCDSEED-TTTLC LQSRRQKQRQMSGENHG--------HISKQGAWKVHTQIDYIHCLVPDLLQITG-------------------------- ---NPCYWGVMDRYEAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYNRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSSTVTGLLEHYKDPSSCMF------------------------------------------FEP LLTVS--------LNRT-FPFSLQYICRAVICRCT----TYDGIDDLP-LPSMLQDFLKEYHYKQKVRVRWLEREP-IKT K------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS6(Chromosome_2:_95940273-95941877) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKKISLKTIRK SFNLNKSKDESDFVVVQQPSLS-EFGKDDSLFGSCYGKDLASCEVNSEDEKG--GKNRSKSESLMGTLKR---------- ---RLSAKQKQKG-KGSTPSGSSADDDT------------------------------FSSSSAPITFKDVRAQRPLRST SLRNHHYSPTPWPLRPTNSEETCIKMEVKVKALVHSSNPSPALNGVRKDFHDLQSDNVFQ-------------------- -----EQNNALKN----------------------------------------TESQNGDLHLHIDEH------------ ----------------------------------------VPVVIGLMPQDYIQYTVPLDEGMYPL-------------- --------------EGSRSYCLDSSSPMEVSTVSSQVGENAFHEEESQVDQDVVVAPDIFVDQAVNGLLIGTTGVVLQNP RVNHSDVPPLSPLLPPMQNN-QIQRNFNGLNGTDAHVAES------------------------------MRCHLNFDPN TAPGVGRVYDSVQNSG----------------------PMVVTSLTEELKKLAK-------------------------- ---QGWYWGPITRWEAEGKLANVPDGSFLV---RDSSDDRYLLSLSFR---SHGKTLHTRIEHS----N--GRFSFYEQ- ----------PDVEG-HTSIVDLIEHSIRDS-ENGAFCYSRSRLPGS----------------------------ATYPV RLTNP--------VSRFMQVRSLQYLCRFVIR-QYTRI---DLIQKLP-LPNKMKDYLQEKHY----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)SOCS7(Chromosome_27:_3866908-3872130) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----GWYWGPMNWEDAEMKLKGKPDGSFLV---RDSSDPRYILSLSFR---SQGITHHTRMEHY----R--GTFSLWCH- ----------PKFEDRCQSVVEFIKRAIMHSKN----VTPPPPLQGL----------------------------PPTPV QLLYP--------VSRFSNVKSLQHLCRFRIR-QLVRI---DHIPELP-LPNLSLQYLRK--------------KNAEL- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Gallus_gallus_(Chicken)CISH(Chromosome_12:_1736930-1741989) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------PHP----LLAEEKIQR-LSLRGIAEDLTE HIMQPLPVPAF------------------------------------------------------------------PEE -PAP-TFAAPEPDGSA----------------PQTRDPEEDLLCIAKTFSYLRE-------------------------- ---SGWYWGSITASEAKQHLQKMPEGTFLV---RDSTHPSYLFTLSVK---TNRGPTNVRIEY-----AD-SKFRLDS-- ------NYLSKPRILAFPDVVSLIQHYVTSCTTESKSEAPYPPPA--------PLPPVQKEVA-----------VAAVHL KLLRP--------LGRRDSIPSLQHLCRLRINRCTT------EVERLP-LPRRMGDYLKQYPFQL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS1(Chromosome_16:_11425834-11426469) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------MVAHNQVAADNAVST-------------AAEPR RRPEPSSSSSS----------------------------------------------------------SS--------A APARPRPCPAVPAPAP------------GDTHFRTFRSHADYRRITRASALLDA-------------------------- ---CGFYWGPLSVHGAHERLRAEPVGTFLV---RDSRQRNCFFALSVK---MASGPTSIRVHF-----QA-GRFHLDG-- ---------SRES-FDCLFE--LLEHYVAA-----------------------------------------------PRR MLGAP--------LRQR-RVRPLQELCRQRIVATV----GRENLARIP-LNPVLRDYLSSFPFQI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS2(Chromosome_12:_93784454-93790809) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---MTLRCLEP------------------------------------------------------------------SGN GGEGTRSQWGTAGSA--------------------EEPSPEAARLAKALRELGQ-------------------------- ---TGWYWGSMTVNEAKEKLKEAPEGTFLI---RDSSHSDYLLTISVK---TSAGPTNLRIEY-----QD-GKFRLDS-- ------IICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAP--------------------------------RNGTVHL YLTKP--------LYT--SAPSLQHLCRLTINKCTG------AIWGLP-LPTRLKDYLEEYKFQV--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS3(Chromosome_17:_77324103-77327397) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MVTHSKFP-------------------------------------------------------------------AAG MSRPLDTSLRLK----------------------TFSSKSEYQLVVNAVRKLQE-------------------------- ---SGFYWSAVTGGEANLLLSAEPAGTFLI---RDSSDQRHFFTLSVK---TQSGTKNLRIQC-----EG-GSFSLQS-- ------DPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSS----EVPEQPSAQPLPGSPPRRAYYIYSGGEKIPL VLSRP--------LSS--NVATLQHLCRKTVNGH-L----DSYEKVTQ-LPGPIREFLDQYDAPL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS4(Chromosome_14:_53990809-54013445) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------MAENNENISKNVDVRPKTSRSR-------- -----------------------------------------------SAD------------------------------ -RKDGY----VWSGKK-LSWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCG---------------- -------HRFLGRSLK--------------------------------------QKLQDAVGQCFPIKN----------- ---------------------------------------------CSSRHSSGLPSKRKIHISELMLDKCP--------- ---------FPPRSDLAFRWHFIKRHTAPINS----KSD----EWVSTDLSQTELRDGQLK---RRNMEEN-----INCF SHTNVQPCVIT--TDNALCREGPMTGSVMNLVSNNSIE---------------------------DSDMDSDDE-ILTLC TSSRKRNKPKWELDDEI---------LQLETPPKYHTQIDYVHCLVPDLLQINN-------------------------- ---NPCYWGVMDKYAAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYSRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSPDITGLLEHYKDPSACMF------------------------------------------FEP LLSTP--------LIRT-FPFSLQHICRTVICNCT----TYDGIDALP-IPSSMKLYLKEYHYKSKVRVLRIDAPEQQC- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS5(Chromosome_2A:_47500543-47502153) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------MDKVGK MWNNFKYRCQNLFGHEGGS-RSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSR-------- -----------------------------------------------RNQNCATEIPQIVEISIEKDN-DSCVT-PGTRL ARRDSYSRHAPWGGKKKHSCSTKTQSSLDAD--KKFGRTRSGLQRRERRYGVSSVHDMDSVSS----------------- -------RTVGSRSLR--------------------------------------QRLQDTVGLCFPMRT----------- ---------------------------------------------YSKQSKPLFSNKRKIHLSELMLEKCP--------- ---------FPAGSDLAQKWHLIKQHTAPVSP----HST--FFDTFDPSLVSTEDEEDRLRERRRLSIEEG-----VDPP PNAQIHTFEAT-AQVNPLYKLGPKLAPGMTEISGDSSA-------------------------IPQANCDSEED-TTTLC LQSRRQKQRQISGDSHT--------HVSRQGAWKVHTQIDYIHCLVPDLLQITG-------------------------- ---NPCYWGVMDRYEAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYNRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSSTVTGLLEHYKDPSSCMF------------------------------------------FEP LLTIS--------LNRT-FPFSLQYICRAVICRCT----TYDGIDGLP-LPSMLQDFLKEYHYKQKVRVRWLEREP-VKA K------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS6(Chromosome_18:_66564151-66566683) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKKISLKTLRK SFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKG--GKNRSKSESLMGTLKR---------- ---RLSAKQKSKG-KAGTPSGSSADEDT------------------------------FSSSSAPIVFKDVRAQRPIRST SLRSHHYSPTPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQ-------------------- -----EQANSLKS----------------------------------------SASHNGDLRLHLDEH------------ ----------------------------------------VPVVIGLMPQDYIQYTVPLDEGMYPL-------------- --------------EGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSP RAGHDDVPPLSPLLPPMQNN-QIQRNFSGLTGTEAHVAES------------------------------MRCHLNFDPN SAPGVARVYDSVQSSG----------------------PMVVTSLTEELKKLAK-------------------------- ---QGWYWGPITRWEAEGKLANVPDGSFLV---RDSSDDRYLLSLSFR---SHGKTLHTRIEHS----N--GRFSFYEQ- ----------PDVEG-HTSIVDLIEHSIRDS-ENGAFCYSRSRLPGS----------------------------ATYPV RLTNP--------VSRFMQVRSLQYLCRFVIR-QYTRI---DLIQKLP-LPNKMKDYLQEKHY----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)SOCS7(Chromosome_17:_19005151-19048833) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------PPPPPPGPLR--------------------------PLAGPSRKGSFKIRLSRLFRTKSCNGG SGGGDGTGKRPSGELAASAA-SLTDMGGSA--------GRELDAGRKPKLTRTQSAF----------------------- ------SPVSFSP--------------------------------------LFTGETVSLVDVDISQR------------ ---------------------------------------------GLTSPH--------PPTPP---------------- -------------------------------------------PPPRRSLS------------------------LLDDI SGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAP-----------------------------------IRAAES LHSQPPQHLQCPLYRP------------------------DSSSFAASLRELEK-------------------------- ---CGWYWGPMNWEDAEMKLKGKPDGSFLV---RDSSDPRYILSLSFR---SQGITHHTRMEHY----R--GTFSLWCH- ----------PKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGL----------------------------PPTPV QLLYP--------VSRFSNVKSLQHLCRFRIR-QLVRI---DHIPDLP-LPKPLISYIRKFYYYDPQEEVYLSLKEAQLI SK-----QKQE-VEPST--------------------------------------------------------------- ----------------------------------------------------------------------- >Pan_troglodytes(Chimpanzee)CISH(Chromosome_3:_51404929-51408918) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------MYLEHTSHCPHHDDDTAMDTPLPRPRP----LLAVERTGQ-RPLWAPSLELPK PVMQPLPAGAF------------------------------------------------------------------PEE VAEG---TPAQTESE-----------------PKVLDPEEDLLCIAKTFSYLRE-------------------------- ---SGWYWGSITASEARQHLQKMPEGTFLV---RDSTHPSYLFTLSVK---TTRGPTNVRIEY-----AD-SSFRLDS-- ------NCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPT--------PALPMPKEDAPSDPALPAPPPATAVHL KLVQP--------FVRRSSARSLQHLCRLVINRLVA------DVDCLP-LPRRMADYLRQYPFQL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Ciona_intestinalis_(Ascidian)SOCS1(Chromosome_3:_4841489-4844693) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKRFRNLSVNK -----RKK--HLDTAVPEIDNVEPQSKDDNVPINQKAKFKFR---------------------IGKTLFR---------- ---TKSAK-KSSSSNESERNSTIAENKN------------------------------GPSSSLTDVQSNQDSPIQVNNS --------------------------------NFLN-DSTQERSCQTDELSNGQAGNVQN-------------------- -------ITPKQH----------------------------------------INGHAGGDQL---HSS----------- ----------------------------------------NYTCNNFTSQGTSE-------------------------- -----------------------NSPNENLYQLPSND----THTNHSG-KLSQLQEED---------------------- -----------TVVPDSTDV--YQTPESLDHGIMGATAAP------------------------------VSPDVNHTFH -TLTSLHVPPTMRKNT----------------------------LTNEFKKLAQ-------------------------- ---QGWYWGPLTRSEAEDKLNETPNGSFLV---RDSSDERYLLSLSFR---SFGRTLHTRIEHS----S--GNFSFYEN- ----------NRMQS-YDSVVDLIMDSVRDSQEAGIFCYSRTRDPLA----------------------------TTYPV RLIHP--------VSRLSQVRTLQYLCRFVIR-QYTRI---DHIESLP-LPNPVKGYLNESYF----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Ciona_savignyi_(Ascidian)SOCS2(reftig_1:_3927523-3932668) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKKIHNLAVTK -----RKKQQENDTAIPKNEKTTSHNYDEQLTNNRKSKFKF----------------------LGKTFFR---------- ---GKGVKSRAVASSEETPNGEDTYHES------------------------------DASCMPAGNNSTQDTTKTIEIQ --------------------------------CSLGGDTRQEKSCQTDDKNEIQSDYVEN-------------------- -------TSFVPHQ---------------------------------------ANGYAGGDQINIPTSS----------- ----------------------------------------VSTFSNIVSSRFDE-------------------------- -----------------------SAVSTNLTQLSVNANNNRTYENESNPIVDQLPSQNG--------------------- ----------THVMPDSPNE--SQSDSGRIQEYPADVEVP------------------------------VSPAVDHNFH NSPLNLTVPRSNKRNT----------------------------LTNEFKNLAQ-------------------------- ---QGWYWGPLSRTEAEDKLNDTPNGSFLV---RDSSDERYLLSLSFR---SFGRTLHTRIEHS----T--GRFSFYEN- ----------NRMQS-YDSVVELITDSVRDSQDAGIFCYSRTRDPLA----------------------------TTYPV RLIFP--------VSRLSQVRTLQYLCRFVIR-QYTRI---DHIESLP-LPNPVKGYLNECYF----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS1(Chromosome_25:_9975299-9975970) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------MVAHNQVAADNAIST-------------AAEPR RRPESSSSSSS----------------------------------------------------------SSSSTSSPSSA APARLRPCPAAAAPAPAP--------APGDTHFRTFRSHAEYRRITRASALLDA-------------------------- ---CGFYWGPLSVHGAHERLRAEPVGTFLV---RDSRQRNCFFALSVK---MASGPTSIRVHF-----QA-GRFHLDG-- ---------SRES-FDCLFE--LLEHYVAA-----------------------------------------------PRR MLGAP--------LRQR-RVRPLQELCRQRIVATV----GRENLARIP-LNPVLRDYLSSFPFQI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS2(Chromosome_5:_23523981-23528860) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---MTLRCLES------------------------------------------------------------------SGN GAEGAQSQWGTAGSA--------------------EEPSPEAARLAKALRELSH-------------------------- ---TGWYWGSMTVNEAKEKLKEAPEGTFLI---RDSSHSDYLLTISVK---TSAGPTNLRIEY-----QD-GKFRLDS-- ------IICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAP--------------------------------RNGTVHL YLTKP--------LYT--SAPPLQHLCRLTINKCTS------TVWGLP-LPTRLKDYLEEYKFQV--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS3(Chromosome_19:_54458856-54459555) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MVTHSKFP-------------------------------------------------------------------AAG MSRPLDTSLRLK----------------------TFSSKSEYQLVVNAVRKLQE-------------------------- ---SGFYWSTVTGGEANLLLSAEPAGTFLI---RDSSDQRHFFTLSVK---TQSGTKNLRIQC-----EG-GSFSLQS-- ------DPRSTQPVPRFDCVLKLVHHYMPAAGAPSFSQPPAEPSSSPSSEVPEQPPAQPLSGNPPRRAYYIYSGGEKIPL VLSRP--------LSS--NVATLQHLCRKTVNGH-L----DSYEKVTQ-LPGPIREFLDQYDAPL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS4(Chromosome_10:_67735433-67749358) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------MAENSESNSKNVDVRPKTSRSR-------- -----------------------------------------------SAD------------------------------ -RKDGY----VWSGKK-LSWSKKSESCSDAETVSAIEKTEVPLRSQERKHSCSSIELDLDHSCG---------------- -------HRFLGRSLK--------------------------------------QKLQDAVGQCFPIKN----------- ---------------------------------------------CSSRHSSGLPSKRKIHISELMLDKCP--------- ---------FPPRSDLAFRWHFIKRHTAPISP----KSD----EWVSTDLSQSELRDGQLKQ--RRNMEE------VSCF SHTSVQPCVIT--SNNSSGRGGPGTDSIVNLASNNSIE---------------------------DSDMDSDDE-IITLC TSSRKRNKPKWEIDEEI---------LQLETPPKYHTQIDYVHCLVPDLLQINN-------------------------- ---NPCYWGVMDKYAAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYSRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSPDITGLLEHYKDPSACMF------------------------------------------FEP LLSTP--------LIRT-FPFSLQHICRTVICNCT----TYDGIDALP-IPSSMKLYLKEYHYKSKVRVLRIDAPEQQC- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS5(Chromosome_11:_28985138-29053248) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------MDKVGK MWNNFKYRCQNLFGHEGGS-RSENVDMNSNRCLSVKEKNISLGDSAPQQQSSPLRENVALQLGLSPSKNSSR-------- -----------------------------------------------RNQNCAAEIPQIVEISIEKDN-DSCVT-PGTRL ARRDSYSRHAPWGGKKKHSCSTKTQSSLDTD--KKFGRTRSGLQRRERRYGVSSVHDMDSVSS----------------- -------RTVGSRSLR--------------------------------------QRLQDTVGLCFPMRT----------- ---------------------------------------------YSKQSKPLFSNKRKIHLSELMLEKCP--------- ---------FPAGSDLAQKWHLIKQHTAPVSP----HST--FFDTFDPSLVSTEDEEDRLRERRRLSIEEG-----VDPP PNAQIHTFEAT-AQVNPLYKLGPKLAPGMTEVNGDSCA-------------------------VPQANCDSEED-TTTLC LQSRRQKQRQVSGDSHA--------HVSRQGAWKVHTQIDYIHCLVPDLLQITG-------------------------- ---NPCYWGVMDRYEAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYNRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSSTVTGLLEHYKDPSSCMF------------------------------------------FEP LLTIS--------LNRT-FPFSLQYICRAVICRCT----TYDGIDGLP-LPSMLQDFLKEYHYKQKVRVRWLEREP-VKA K------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS6(Chromosome_24:_7303047-7304704) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------MKKISLKTFRK SFNLSKSKEDAEFMVVQQPALAGDFGKEESLFGSCYGKEMAGCELHGEDEKGGGGKNRAKSESLMGTLKR---------- ---RLSAKQKAKG-KGGAAAGGAADEDT------------------------------FSSSSAPLVFKDARAPRPMRST SLRSHHYSPTPWPLRPTASEETCIRMEVRVKALVHSPGTGPALNGVRKDFGELRPAAEPAC------------------- --PCPEPPAAPGS----------------------------------------PAPVAGDLRLRLGEH------------ ----------------------------------------VPVVLGLLPQDYLPYTVPLDG------------------- ------------------------SSPMX--------------------------------------------------- -------------------------------GPDAHAADS------------------------------VRCHLNFDPT SAPGVARVYDSVQSSG----------------------PLAVTSLTEELKKLAK-------------------------- ---QGWYWGPITRWEAEGKLANVPDGSFLV---RDSSDDRYLLSLSFR---SHGKTLHTRIEHS----N--GRFSFYEQ- ----------PDVEG-HTSIVDLIEHSIRDS-ENGAFCYSRSRLPGS----------------------------ATYPV RLTNP--------VSRFMQVRSLQYLCRFVIR-QYTRI---DLIQKLP-LPNKMKDYLQEKHY----------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)SOCS7(Chromosome_19:_39648073-39672758) -------------------------------------------------------------------------------- ------------------MVFRNVGRPPEEEDAEAAQEPGP--SELLCPRHRCALD------------------------ -------PKALPP---------------------------GLALERTWGP------AAGLEAQ----------------- -----LAALGLGQPAGPGVKTVGGGCCPCPCPPQPP---------------PPQPQPPAAAP------QAGEDPTETSDA LLVLEGLES-EAESLETNSCSEEELSSPGR------GGG-GGGRLLLQTPGPELPPVPFPMQDLVPPGRL---------- ---SRGEQPQQP----PPPPPPPGPLR--------------------------PLAGLSRKGSLKIRLSRLFRTKSCNGG SGGGDGAGKRPSGELVASAA-SLTDMGGSA--------GRELDAGRKPRLTRTQSAF----------------------- ------SPVSFSP--------------------------------------LFTGETVSLVDVDISQR------------ ---------------------------------------------GLTSPH--------PPTPP---------------- -------------------------------------------PPPRRSLS------------------------LLDDI SGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAP-----------------------------------IRAAES LHSQPPQHLQCPLYRP------------------------DSSSFAASLRELEK-------------------------- ---CGWYWGPMNWEDAEMKLKGKPDGSFLV---RDSSDPRYILSLSFR---SQGITHHTRMEHY----R--GTFSLWCH- ----------PKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGL----------------------------PPTPV QLLYP--------VSRFSNVKSLQHLCRFRIR-QLVRI---DHIPDLP-LPKPLISYIRKFYYYDPQEEVYLSLKEAQLI SK-----QKQEVLEPST--------------------------------------------------------------- ----------------------------------------------------------------------- >Bos_taurus_(Cow)CISH(Chromosome_22:_50320205-50325617) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------MVLCVQGLCP----LLAVEQIGQ-RPLWAQSLELPQ QVMQPLSAGAF------------------------------------------------------------------LEE AVEE---SPAQPERE-----------------PKVVDPEEDLLCIAKTFSYLRE-------------------------- ---SGWYWGSITASEARQHLQKMPEGTFLV---RDSTHPSYLFTLSVK---TTRGPTNVRIEY-----AD-SSFRLDS-- ------NCLSRPRILAFPDVVSLVQHYVASCAADTRSDSPDLATT--------PALPTPKEDAPGDPALP----ATAVHL KLVQP--------FVRRSSTRSLQHLCRLVINRLVV------DVDCLP-LPRRMADYLRQYPFQL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS1(SuperContig_scaffold_53:_3889083-3890456) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------RRARSRASCGRGSCTAPRPGA-------------------------- ---CAFYWGPLSVHGAHER-RSEPVGTFLV---RDSRQ-NCFFALSVK---MASGPTSIRVHF-----QA-GRFHLDG-- ---------SRES-FDCLFE--LLEHYVAA-----------------------------------------------PRR LLGAP--------LRQR-RVRPLQELCRQRIVATV----GRENLARIP-LNPVLRDYLSSFPFQI--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS2(SuperContig_scaffold_2:_87913758-87916027) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---MTLRCLEP------------------------------------------------------------------SGN GAEGTRSQWGIAASA--------------------EEPSPEAARLATALRELSQ-------------------------- ---TGWYWGSMTVNEAKEKLKEAPEGTFLI---RDSSHSDYLLTISVK---TSAGPTNLRIEY-----QD-GKFRLDS-- ------IICVKSKLKQFDSVVHLIDYYVQMCKDKGTSPEAP--------------------------------RNGTVHL YLTKP--------LYT--SAPSLQHLCRLIINKCTG------TIWGLP-LPTRLKDYLEEYKFQV--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS3(SuperContig_scaffold_49:_4513057-4513743) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MVTHSKFP-------------------------------------------------------------------AAG MSRPLDTSLRLK----------------------TFSSKSEYQLVVNAVRKLQE-------------------------- ---SGFYWSAVTGGEANLLLSAEPAGTFLI---RDSSDQRHFFTLSVK---TQSGTKNLRIQC-----EG-GSFSLQS-- ------DPRSTQPVPRFDCVLKLVHHYMPPAGAPSASSPPPEPSS-PSSEVPEQPPAQPPTGSTPRKAYYIYSGGEKIPL VLSRP--------LSS--NVATLQHLCRKTVNGH-L----DSYEKVTQ-LPGPIREFLDQYDAPL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS4(SuperContig_scaffold_9:_30582363-30583673) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------SIENNSKNVDVRPKTSRSR-------- -----------------------------------------------SAD------------------------------ -RKDGY----VWSGKK-LSWLKKSESCSDAETVDTVEKTEVPLRSQERKHSCSSIELDLDHSCG---------------- -------HRFLGRSLK--------------------------------------QKLQDAVGQCFPIKN----------- ---------------------------------------------CSSRHSSGLPSKRKIHISELMLDKCP--------- ---------FPPRSDLAFRWHFIKRHTVPINP----KSE----EWVSTDLSQSELRDGQLKQ--RRNMEED-----VNCF SHTNVQPCVIT--TNSASCKGDPMTGSVINLVSNNSIE---------------------------DSDMDSDDE-IITLC TSSRKRNKPKWELDDEI---------LQLETPPKYHTQIDYVHCLVPDLLQINN-------------------------- ---NPCYWGVMDKYAAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYSRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSPDITGLLEHYKDPSACMF------------------------------------------FEP LLSTP--------LIRT-FPFSLQHICRTVICNCT----TYDGIDALP-IPSSMKLYLKEYHYKSKVRVLRIDAPEQQ-- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS5(SuperContig_scaffold_52:_15142133-15143743) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------MDKVGK MWNNFKYRCQNLFSHEGGS-RSENMAVNSNRCSSVKEKNTSGEDSAPQQQSSPLRENVALHLAVSPSKNPSR-------- -----------------------------------------------RSQNCAAEIPQIVEISIEKEN-DPCVTTPGTRL ARRDSYSRHAPWGGKKKHSCSTKTQSSLDSD--KKFGRTRSGLQRRERRYGVSSVHDMDSVAS----------------- -------RTGGSRSLR--------------------------------------QRLQDTVGLCFPMRT----------- ---------------------------------------------YNKQSKP-FSNKRKIHLSELMLEKCP--------- ---------FPAGSDLAQKWHLIKQHTAPVSP----HST--FFDTFDPSLVSTEDEEDRLRERRRLSIEEG-----VDPP PNAQIHTFEAT-AQVNPLYKLGPKLAPGMTEISGDSSS-------------------------VPQANCDSEED-TTTLC LQSRRQKQRQVSGDSHT--------HVSRQGAWKVHTQIDYIHCLVPDLLQITG-------------------------- ---NPCYWGVMDRYEAEALLEGKPEGTFLL---RDSAQEDYLFSVSFR---RYNRSLHARIEQ-----WN-HNFSFDA-- ---------HDPCVFHSSTVTGLLEHYKDPSSCMF------------------------------------------FEP LLTIS--------LNRT-FPFSLQYICRAVICRCT----TYDGIDGLP-LPSMLQDFLKEYHYKQKVRVRWLEREP-VKA K------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)SOCS7(SuperContig_scaffold_31:_20795318-20825968) -------------------------------------------------------------------------------- ---------------------RNVGRRQSSRR-EAAPEPGP--SELLCP-HRCALD------------------------ -------PKSLPS---------------------------GLALERTWGP------AAGLEAQ----------------- -----LAALGLGQPAGPGVKMVGAGCCPCPCPAQPP---------------PPQPQPPAATP------QAGEDPTETSDA LLVLEGLES-EAESLETNSCSEEELSSPGR------GGG-GGGRLLLQPPGPELPPVPFPLQDLVPRARL---------- ---SRGEQPQQP----LPPPPPPGPLR--------------------------PLAGPSRKGSLKIRLSRLFRTKSCNGG SGSGDGTGKRPSGELAASAA-SLTDMGGSA--------GRELDAGRKPRLTRTQSAF----------------------- ------SPVSFSP--------------------------------------LFTGETVSLVDVDISQR------------ ---------------------------------------------GLTSPH--------PPTPP---------------- -------------------------------------------PPPRRSLS------------------------LLDDI SGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRVAP-----------------------------------IRATES LHSQPPQHLQCPLYRP------------------------DSSSFAASLRELEK-------------------------- ---CGWYWGPMNWEDAEMKLKGKPDGSFLV---RDSSDPRYILSLSFR---SQGITHHTRMEHY----R--GTFSLWCH- ----------PKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGL----------------------------PPTPV QLLYP--------VSRFSNVKSLQHLCRFRIR-QLVRI---DHIPDLP-LPKPLITYIRKFYYYDPQEEVYLSLKEAQLI SK-----QKQE-VEPST--------------------------------------------------------------- ----------------------------------------------------------------------- >Loxodonta_Africana_(Elephant)CISH(SuperContig_scaffold_12:_16922581-16927134) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------MVLCVQGPCS----LLAEEQIGQ-QTLKARSLELPE SAMQPLPVGVF------------------------------------------------------------------LEE VAEE---IPAQLESEQ----------------PKVLDPEEDLLCIAKTFSYLRE-------------------------- ---SGWYWGSITASEARQHLQKMPEGTFLV---RDSTHPSYLFTLSVK---TTRGPTNVRIEY-----AD-SSFRLDS-- ------NCLSRPRILAFPDVVSLVQHYVASCAADTRSNSPDPAPA--------PALPAPKEDATSNPVLPAPT-ATAVHL KLVQP--------FVRRSSARSLQHLCRLVINRVVA------DVDCLP-LPRRMADYLRQYPFQL--------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------- >Xenopus_tropicalis_(Frog)SOCS1(Scaffold_GL173342.1:_447301-451397) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------MVANSKVEADNAVAD---------------