>Homo_sapiens_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MAPRPRARPGVAVACCWLLT---------------------------------------VVLR CCVSFNVDVKNSMTFSG-PVEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPKNRTGDVYKCPVGRGESLP-CVKL-DL P------VNTSIPNVTE-VKENMTFGSTLVTNPNG-GFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP------ ------------------------------------------------------------VQECSTQLDIVIVLDGSNSI YP--WDSVTAFLNDLLERMDIGPKQT-QVGIVQYGE---------------------------NVTHEFNLNK--YSSTE EVLVAAKKIVQRGGRQ---TMTALGIDTARK------------------------------------EAFTEA-RGARRG VKKVMVIVTDGESHDN--HRLKKVIQDCEDENIQRFSIA-ILGSYNRGNLS---TEKFVEEIKSIASEPTEKHFFNVSDE LALVTIVKTLGERIF-ALEAT----------------------------------------------------------- -----------ADQSAASFEMEMSQTGFSAHYSQ----DWVMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMQKASQIIIPRN TTFNVESTKK----------------------------------NEPLASYLG------YTVNSATASSGD-----VLYI AGQPRYNHTGQ---VIIYRME---------DGNIKILQTLSGE---QIGSYFG-SILTTTDIDKDSNTDILLVG---APM YMGTEKEE----QGKVYVYALNQTR----------FEYQMS-------LEPIKQTCCSSRQHNSCTTENKNEPCGARFGT AIAAVKDLNLDGFN---DIVIGAPLEDD-------HGGAVYIYHGSGKTIRK---------EYA-QRIPSG----GDGKT LKFFGQSIHGEM-DLNGDGLT-------------------------DVTIGGLGGAALFWSR------------------ ---------------------------------DVAVVKVTMNFEPNKV------------------------------- ----------------------------------NIQKKNCHMEGKETVCINATVCFDVKLKSKE----DTIYEADLQYR VTLDS----LRQISRSFFSGTQE--------------------------------RKVQRNITVR--KSECTKHSFYML- -------------------------------------------------------------------------------- --------------------------------------------------DKHDFQDSVRITLDFNLT-DPENGP----- -----------------------------------------------VLDDSLPNSVHEYIPFA---KDCGNKEKCISDL SLHVATTEKD------------------------------------------------------------------LLIV RSQNDKFNVSLTVKNTK----------DSAYNTRTIVHYSPNLVFSGIEAI----------------------------- -------------QKDSCESNHNITCK-----VGYPF-LRRGEMVTFKILFQFNT-SYLMEN-----------VTIYLSA TSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSAS---EYHISIAANETVPEVINSTED--------------------- IGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNG-----------------------------YPVLYPTGLSSS--EN ANCRPHI------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------FEDPFSINSGKKMTTS-TDHLKRGTILD--- -------------------------------------------------------------------------------- -------------------------------------------------CNTCKFATITCNLTSSDISQ---VNVSLILW KPTFIK---------------------------------------------SYFSSLNLTIRGELRSENA-SLVLSSSNQ KRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Mus_musculus_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MVPRRPASLEVTVACIWLLT---------------------------------------VILG VCISFNVDVKNSMSFSG-PVEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPKARTGDVYKCPVGRERSMP-CVKL-DL P------VNTSIPNVTE-IKENMTFGSTLVTNPKG-GFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSFAP------ ------------------------------------------------------------VQECSTQLDIVIVLDGSNSI YP--WESVTAFLNDLLKRMDIGPKQT-QVGIVQYGA---------------------------NVTHEFNLNK--YSSTE EVLVAANKIGRRGGLQ---TMTALGIDTARK------------------------------------EAFTEA-RGARRG VKKVMVIVTDGESHDN--YRLKQVIQDCEDENIQRFSIA-ILGHYNRGNLS---TEKFVEEIKSIASEPTEKHFFNVSDE LALVTIVKALGERIF-ALEAT----------------------------------------------------------- -----------ADQSAASFEMEMSQTGFSAHYSQ----DWVMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMQKANQIVIPHN TTFQTEPTKM----------------------------------NEPLASYLG------YTVNSATIP-GD-----VLYI AGQPRYNHTGQ---VVIYKME---------DGDVNILQTLSGE---QIGSYFG-SVLTTIDIDKDSYTDLLLVG---APM YMGTEKEE----QGKVYVYAVNQTR----------FEYQMS-------LEPIKQTCCSSLKDNSCTKENKNEPCGARFGT AVAAVKDLNVDGFN---DVVIGAPLEDD-------HAGAVYIYHGSGKTIRK---------EYA-QRIPSG----GDGKT LKFFGQSIHGEM-DLNGDGLT-------------------------DVTIGGLGGAALFWAR------------------ ---------------------------------DVAVVKVTMNFEPNKV------------------------------- ----------------------------------NIQKKNCRVEGKETVCINATMCFHVKLKSKE----DSVYEADLQYR VTLDS----LRQISRSFFSGTQE--------------------------------RRIQRNLTVR--ESECIRHSFYML- -------------------------------------------------------------------------------- --------------------------------------------------DKHDFQDSVRVTLDFNLT-DPENGP----- -----------------------------------------------VLDDALPNSVHGHIPFA---KDCGNKERCVSDL TLDVSTTEKN------------------------------------------------------------------LLIV RSQNDKFNVSLTVKNKG----------DSAYNTRTVVQYSPNLIFSGIEEI----------------------------- -------------QKDSCESNQNITCR-----VGYPF-LRTGDVVNFKIIFQFNT-SHLSEN-----------AIIHLSA TSDSEEPLESLYDNEVNISIPVKYEVGLQFYSSAS---EHHISVAANETVPELINSTKD--------------------- IGDEINVFYTIRKRGHFPMPELRLAISFPNLTSDG-----------------------------YPVLYPTGWSSS--DN VNCRPRS------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LEDPLGINSGKKMTISKSEVLKRGTIQD--- -------------------------------------------------------------------------------- -------------------------------------------------CSTCKIATITCHLLPSDVSQ---VNVSLILW KPTFIK---------------------------------------------AHFSSLNLTIRGELQSENS-SLTLSSSNR KRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Canis_familiaris_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------M TSIKCYNMNLTELFMDSSRWRKPMRLWQLIHCSSAMSFSGTR----------------------------MLLPGAVVLG FCVSFNVDVKNSMTFSG-PVEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPKNKTGDVYKCPVGRGKPLP-CIKL-DL P------VNTSIPNVTE-VKENMTFGSTLVTNPNG-GFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP------ ------------------------------------------------------------VRECSTQLDIVIVLDGSNSI YP--WESVTAFLNDLLERMDIGPKQT-QVGIVQYGE---------------------------NVTHEFNLNK--YSSTE EVLVAANQIIQRGGRQ---TMTALGIDTARK------------------------------------EAFTEA-RGARRG VKKVMVIVTDGESHDN--HLLNKVIQDCEDENIQRFSIA-ILGSYNRGNLS---TEKFVEEIKSIASEPTEKHFFNVSDE LALVTIVEALGERIF-ALEAT----------------------------------------------------------- -----------ADQSAASFEMEMSQTGFSAHYSQ----DWVMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMQKANQIIIPHN TTFNVESTKK----------------------------------NEPLASYLG------YTVNSATVS-GA-----VLYI AGQPRYNHTGQ---VVIYRMD---------DGDIKILQTLSGE---QIGSYFG-SVLTTIDIDKDSNTDILLVG---APM YMGTEKEE----QGKVYVYALNQTR----------FEYQMS-------LEPIKQTCCSSLKHNSCTKENKNEPCGARFGT AIAAVRDLNLDGFD---DIVIGAPLEDD-------HGGAVYIYHGSGKTIRK---------EYA-QRIPSG----GDGKT LKFFGQSIHGEM-DLNGDGLT-------------------------DVTIGGLGGAALFWSR------------------ ---------------------------------DVAVVKVTMNFEPNKV------------------------------- ----------------------------------NIQKKNCRVEGKETVCINATVCFDVKLKSKE----DTIYIADMQYR VTLDS----LRQISRSFFSGTQE--------------------------------RKIQRNITVE--ESECTKLSFYML- -------------------------------------------------------------------------------- --------------------------------------------------DKHDFRDSVRITLDFNLT-DPENGP----- -----------------------------------------------VLDDSLPNSVHEYIPFA---KDCGNKEKCISDL ALKVSTTEKG------------------------------------------------------------------LLIV RSHNDKFNVSLTVKNKK----------DSAYNTRTIVHYSPNLIFSGIEAI----------------------------- -------------QKDSCESNHNLTCK-----VGYPF-LRRGEEVTFKILFQFNT-SYLMEN-----------VVIHLSA TSDSEEPPEALSDNEVNISIPVKYEVGLQFYSSAS---EYHISIAANETVPEVINSTED--------------------- IGDEINIFYLIRKSGHFPMPELKLSISFPNLTSDG-----------------------------YPVLYPSGWSSS--NN ANCRPSS------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LQDPLGVNSGKKTIISKSEDLKRGTIPD--- -------------------------------------------------------------------------------- -------------------------------------------------CSTCKFATITCNLIPSDMSQ---INVSLIVW KPTFIK---------------------------------------------ARFSSLNLTVRADLQSENT-SLILSTGNQ KREFAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Bos_taurus_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------LTLCNWMFVSSLK----------------------------------------VVLR FCVSFNIDVKNSMTFSG-PVEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPKNRTGDVYKCPVGRSESLP-CIKL-DL P------VNTSIPNVTE-VKENMTFGSTLVTNPKG-GFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP------ ------------------------------------------------------------VQECSTQLDIVIVLDGSNSI YP--WESVTAFLNDLLKRMDIGPKQT-QVGIVQYGE---------------------------NVTHEFNLNK--YSSTE EVLVAAKKIVQRGGRQ---TMTALGIDTARK------------------------------------EAFTEA-RGARRG VKKVMVIVTDGESHDN--HRLNKVIQDCEDESIQRFSIA-ILGSYNRGNLS---TEKFVEEIKSIASEPTEKHFFNVSDE LALVTIVEALGERIF-ALEAT----------------------------------------------------------- -----------VDQSAASFEMEMSQTGFSAHYSQ----DWIMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMQKADQSVIPQN TTFNVESTKK----------------------------------NEPLASYLG------YTVSSATTP-GD-----VLYI AGQPRYNHTGQ---VVIYRME---------GRDIRILQTLNGE---QIGSYFG-SVLTTTDIDKDSNTDILLVG---APM FMGREKEE----QGKVYVYALNQTR----------FEYQMS-------LEPIKQTCCSSLKHNSCTKENRNEPCGARFGT AIAAVKDLNLDGFN---DIVIGAPLEDD-------HGGAVYIYHGSGKTIRE---------EYA-QRIPSG----GDGET LKFFGQSIHGEM-DLNGDGLT-------------------------DVTIGGLGGAALFWSR------------------ ---------------------------------DVAVVKVTMNFEPNKV------------------------------- ----------------------------------NIQKKNCRVEGKETVCINGTVCFNVKLKSKE----NVVYEADMQYR VTLDS----LRQISRSFFSGTQE--------------------------------RKIQRNITVR--ESECTKHSFYML- -------------------------------------------------------------------------------- --------------------------------------------------DKHDFRDSVRITLDFNLT-DPENGP----- -----------------------------------------------VLDDSLPNSVHEYIPFA---KDCGNKEKCVSDL ALDVSTTEKG------------------------------------------------------------------LLIV KSHNDKFNVSLTVKNKK----------DSAYNTRTIVNYSPNLIFSGIEAI----------------------------- -------------QKDSCESNHNITCK-----VGYPF-LRKGEMVTFKILFQFNT-SYLMEN-----------VIIHLSA TSDSEEPPETLFDNEVNISIPVKYEVGLQFFSSAS---EYHISIAANETVPEIINSTED--------------------- LGNEIDIFYLIRKSGHFPMPELKLTISFPNVTSDG-----------------------------FPVLYPSGWSSS--EN VNCIPSN------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LQDPFGINTGKKMMISKSEDIKRGTILD--- -------------------------------------------------------------------------------- -------------------------------------------------CSACKFATITCNLIPSDMSQ---VNVSLILW KPTFIK---------------------------------------------AHFSSLNLTVRAELQSENA-TLVLSAGNQ KRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Monodelphis_domestica_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------MKLVRKDIEKDNAGQVTLVPEEPEDMWHTYNLLQVG DSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVETIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQ WDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRKRRGNCSQHDRALERFYEQVVQAIQRH IHFDVVKCVLVASPGFVREQFCDYMFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVK ALDDFYKMLQHEPDRAFYGLKQVEKANEALAIDTLLISDELFRHQDVATRSRYVKLVDSVKENAGTVRIFSSLHVSVVLG FCVSFNVDVKNAMTFSG-PVEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPKNRTGDVYKCPVGRGESLP-CIKL-DL P------VYTSIPNVTE-VKENMTFGSTLVTNPKG-GFLACGPLYAYRCGHTYYTTGICSDVDSKFQVVNSIAPS----- ------------------------------------------------------------VQGCNTQLDIVIVLDGSNSI YP--WTSVTDFLNSLLGKMDIGPKQT-QVGIVQYGE---------------------------NVTHEFNLNK--YTTTE EVLIAANQIVQRQGRQ---TMTALGIDTARK------------------------------------EAFTKA-RGARSG VKKVMVIVTDGESHDN--HRLNEVIQDCEDEDIQRFSIA-ILGHYNRGNLS---TEKFVEEIKSIASEPTEKHFFNVSDE LALVTIAEVLGERIF-ALEAT----------------------------------------------------------- -----------TDLSAASFEMEMSQTGFSAHYSQ----DWVMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMQKDNQIITPQN NSFNVESTKK----------------------------------NEPLASYLG------YMVNSATIP-GD-----VIYI AGQPRYNHTGQ---VITYTME---------GQEIKIIQTLNGE---QIGSYFG-SVLTTIDIDKDSFTDLLLVG---APM YMGTEKEE----QGKVYVYALNQTR----------FEYQMS-------LEPIKQTCCSSLKHDSCKKKNKNEPCGARFGT AIASVKDLNLDGFN---DVVIGAPLEDD-------HGGAVYIYHGSGKTIRK---------EYA-QRIPSG----GDGET LKFFGQSIHGEM-DLNGDGLT-------------------------DVTIGGLGGAALFWSR------------------ ---------------------------------DVAEVKVTMAFAPNKV------------------------------- ----------------------------------NIQKKNCKMEGKETVCINATMCFNVKLKSKE----DTIYEADLQYR VTLDS----VRQISRSFFSGTQE--------------------------------RKIQRNITVR--GSECIKHYFYMLA SKSCIIA------------------------------------------------------------------------- --------------------------------------------------DKHDFRDSVKVSLDFNLS-DPENGP----- -----------------------------------------------VLDGDLPNSVYEYIPFA---KDCGNKEKCISDL ALTVSTSGKD------------------------------------------------------------------LLIV KSHSDKFNVSLTIMNKK----------DSAYNTRAIVQASPNVIFSGIEGI----------------------------- -------------QKDSCESNQNITCK-----VGYPF-LKGGEEISFKILFQFNT-SYLTDN-----------VTIHISV TSDSEEPLEALFDNEVDISIPVKYEAELQFSSSAS---EYHISIAANDTVPDIINSTSD--------------------- IGNEINVFYSIQKSGHIPIPELSLKISFPNLTSNE-----------------------------YPVLYLTGWSSS--DN VNCRPRS------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LQDPFNIKFGKKMIPK-SGELKRGTILD--- -------------------------------------------------------------------------------- -------------------------------------------------CDTCKYATIKCNVIPSDKSQ---VNVTFILW KSTFIK---------------------------------------------ASFSSLNLTIKAELQSENS-SLVLSSGNQ KRELAIQISKDLVPGRVPLWVILLSAFAGFLLLMLLILALWKIG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Gallus_gallus_ITGA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------MSSSGTRMWLHVP-------------------------------------------ALFH LIGASNVDVKNAMTFSG-PLEDM-FGYTVQQYENEE---GKWVLIGSPLVGQPEKRTGDVYKCPVGRDSQSP-CIKL-NL P------DATSVPNVME-VKENMTLGTTLVTNPKG-GFLACGPLYAYKCGRLHYTTGVCSNVSSTFETVKAIAPS----- ------------------------------------------------------------VQECKTQLDIVIVLDGSNSI YP--WESVTAFLNSLLRNMDIGPQQT-QVGIVQYGQ---------------------------TVVHEFYLNT--YSTTE EVMDAALRIRQRGGTQ---TMTALGIDTARE------------------------------------EAFTEA-HGARRG VQKVMVIVTDGESHDN--YRLQEVIDKCEDENIQRFAIA-ILGSYSRGNLS---TEKFVEEIKSIASKPTEKHFFNVSDE LALVTIVEALGERIF-ALEAT----------------------------------------------------------- -----------TDQQAASFEMEMSQAGFSAHYSQ----DWVMLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMVKDSDISIPSN DTFRDRHSEK----------------------------------IEPLAAYLG------YTVNSALTP-GG-----VLYI AGQPRYNHTGQ---VIIYKME---------GREVKVLQRLKGE---QIGSYFG-GVITTIDINRDSFTDLLLVG---APT YMGTEKEE----QGKVYVYALNKTK----------FEYQMS-------LEPIKQTCCSPLKHDTC-KVLKNEPCGARFGT AIAAVKDLNLDGYN---DIVIGSPLEDD-------HRGAVYIYHGHGNTISK---------KYT-QRIASG----GDGEK VKFFGQSVHGEM-DLNDDGLI-------------------------DVTIGGLGGAALFWSR------------------ ---------------------------------DVAEVNVSMQFMPKSI------------------------------- ----------------------------------NIQQQNCQINKRKTICINATICFKTRLKSKE----D-IFESSLQYW ITLDA----QRQISRSLFTETHE--------------------------------RKMQKNITIK--GSECIKHNFYML- -------------------------------------------------------------------------------- --------------------------------------------------DKPDFQDSVKVLLEFNFS-DPESGP----- -----------------------------------------------VLDSNLPNSISEYIPFT---KDCGAKNKCISDL ALNVKASIAGD--------------------------------------------------------------SSSPFIV KSRNDRFTIQLSIKNKK----------DSAYNTRALVQYSPNIIFAGIEDI----------------------------- -------------QKDSCESNHNITCK-----VGYPF-LKPEEEISFKISFQFNA-SYLLEN-----------ATVDVYA TSDSEEPPETLRDNRGQVTIPVKYEVGLIFVSVFK---EHHVIIAANETIPTAINTTEQ--------------------- IGDEVTLHYRIEKGEHFPMPNLTLQILYPDVTTAK-----------------------------NTLLYITTLSHS--QN AICKSSY------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------PVDHLKIGSGKSYVLPKIKEPTKDTIME--- -------------------------------------------------------------------------------- -------------------------------------------------CDTFSCASINCALAPSDISQ---VNVSLRVW KPTIIK---------------------------------------------ASIHSLTLVVKALLRSENS-SLILRNDHQ KLETMIKISKELPPGSVPLWVILLSIFAGLLILALLIFALWKAG----------------------FFKRP--------- -----------------------------------------------------------LKKKMEK-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Danio_rerio_ITGA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------MLSGVYQFTLAAL--------------------------------------------LALLP WLSCFNVDEKNRMSFSG-PVEDM-FGYTVQQFENSE---GKWVLIGSPLTGQPAKRTGDVYRCRVGSNSDSK-CEKF-LL S------ENTTIPNINE-VKENMTMGTTLVVNPDGNGFLACGPQYGYMCGKQQYITGICSNVSSSFKVLNSIAPT----- ------------------------------------------------------------VRECSQDMDIVIVLDGSNSI YP--WDHITDFLVKFLQNIEIGP--A-RVGIVSYGD---------------------------DVGHVFNLSQ--FSNTK ELVKNAADIRQRTGHK---TMTALGIDTARK------------------------------------EAFTVE-RGARPG VKKVMVIVTDGESHDH--HNLKSVIDQCQEDGIERFAVA-VLGDYNRQNKSIDEIKKFIEEIEYIASETKSDHFFNVSDE RALVTIVDTLGSKIF-ALEAT----------------------------------------------------------- -----------SGKHTSSFEMEMSQAGFSAHTSK----AGVMLGAVGAFDWNG--------------------------- -----------------------------------------------------------------TVVMQAGNEFVVPKK NTFHNPSVQR----------------------------------YEGMAGYVG------YDVQSAYTP-NG-----VLYI TGAPRFNHSGR---VTVYRFD---------GENVTIVQTLKGE---QIGSYFG-SVLQTHDIDGDNYTDILLVA---APM FMGPERDE----QGQVYVYKLNESGL---------FEHEMT-------LKPVNQTCCSGHSHNNCKIVSKNEPCGARFGT AIAAVPDLNLDKFS---DIVIGSPLEND-------HRGAVYIYHGSQKSIKE---------KYV-QRIAAG----GDGES MKFFGQSIHGIM-DLNDDGII-------------------------DVTIGGIGGAALYWSR------------------ ---------------------------------DVAELLAEMTFDPIKI------------------------------- ----------------------------------NLQHTCQVHG-KTTVCVKTRVCFKYRIKSVK----EMNTGTVIRYS LTLDS----LRAVARGRFNETED--------------------------------RRLQKNESIR--NKFCREHTFYTD- -------------------------------------------------------------------------------- ---------------------------------------------------KLDFRDPIMVTLEFGLA-DEDKGP----- -----------------------------------------------VLDGELPTSLNKTVSFPPARVDCGSNEKCVANL HLQASANISS-------------------------------------------------------------------LLI KSNQEKFYVNIDIKNTG----------DNAYNTKVTLSHTENINYVKVEPK----------------------------- -------------DKDCETNHTRIVCA-----VGYPF-LKTKDRETFKIQFEPNP-SLIRKD-----------IVINVTA TTDSEQSDSALKRNFETIIIPVRHEASMRFTAYNKYMKEDHIILKEKETIPSVFNHTSV--------------------- IGDEVKISYTIEKDPDMPSPPVKLTIMFPYQTSAK-----------------------------NFLLYLTDLSYT--AG IRCSAD-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------WINPLKIQPSKPHSLNTKKETLSIYLLSCKE -------------------------------------------------------------------------------- -------------------------------------------------KENP-CQSFSCFIPSGDFNQ---INTTFRLW RPTFIK---------------------------------------------GEFSTIHMAVDAKLETQNTDLFVLNENIK TREVRIQVTKDIRTG-IPLWIIILSILIGLLILALVIFALWKAG----------------------FFKRK--------- -----------------------------------------------------------SVEEMNEDKKDTD-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Tetraodon_nigroviridis_ITGA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------SLSPSSPP----------------------------------------------------TALLA CVLSFNVDQKNSKSFSGGSLEDL-FGYTVQQFENSE---GKWVLIGSPLLGQPAKRTGDVYKCPVD-KEHNT-CVKL-EL P------KNTTVPNLHE-VKENMAMGTTLVTNPSG-GFLACGPQYGYMCGQQQYISGVCANVSSSFQVLNSIA-S----- ------------------------------------------------------------VQECAKELDIVILLDGSNSI YP--WPSITDFLERFIKTIDIGPKLS-QVGIVSYGE---------------------------TVTHNVNLSQ--FDNTA ALMDFVRQLPQQTGFK---TMTFMGINTTRL------------------------------------EAFLPE-RGARQG VKKVMVIVTDGESHDF--HALDEVIAACDRDGIERFGIA-VLGDYNRQNKSKDEIQKFIKEIQSISSEPLKDHFFN-SDE VALLTIVDTLGSRIF-ALEAT----------------------------------------------------------- -----------SSKYTSSFEMEMSQTGFSAHTSK----EGVLLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVVMHTSGGTIVPGK TQFYDPSVEAG---------------------------------YERLAGYLG------YDVQSASTP-DG-----VLYI TGAPRYNHTGR---VVVYHLN---------KTEVVVSQILKGE---QIGSYFG-SVLQTLDVDGDSFTDLLLVG---APM FMGPDKDE----QGQVYVYRLKQNGQ---------FEHQFT-------LKPVNQSCCTAHSRS---CRIKNEPCGARFGT AIAAVSDLNLDNFT---DVAIGAPLEND-------HRGAVYIYHGDKMTLKE---------KFV-QRIAAG----GDGSK MKFFGQSIHGVM-DLNGDGIT-------------------------DVTIGGLGGVSQFWSR------------------ ---------------------------------DVAELHANLTFDPTKI------------------------------- ----------------------------------NLQQAQCEHGGRRSTCVTANVCFSYSVKSKQW---DPASSTEIRYD LTLDA----VRTKARASFIEGD---------------------------------RKISRTFYIR--QSRCRNETFVMEA -------------------------------------------------------------------------------- ---------------------------------------------------RPDFRDPLLVTLDFGLT-EEDRGP----- -----------------------------------------------ILDESLPRSINRTILL----VDCGSEEKCIADL SLAAKASETW-------------------------------------------------------------------MLI KSSNDKIDVDITVRNRK----------DNAYNTKVTLSFTPNINFINVET------------------------------ -------------DIVCSLLEAKVECA-----VGYPF-FGSMEEKSFKVKFEANP-KYVEEF-----------ILINVTA TSDSEELPSTLHDNSVQISIPVKYEAGINFAVWP---VDKHVVVRVGEEYPSTINNT-T--------------------- IGEEITMTYTLEMTGATPTPAIDLNVTYPHLSPRG-----------------------------NNLLYLTHMGAS--PQ VTCNTK-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------PKEIN-WDVTVLSPLKETLSDFLLS--- -------------------------------------------------------------------------------- -------------------------------------------------CQNLQCASFSCSIPENTSSQ---VNVSFRLW KPTFIK---------------------------------------------GDFSSLFMRVNASLSVRNSQLFQLSS-SQ RTQFTIQVSKETLGG-IPIWIIIISILIGILILALVIFILWKMG----------------------FFKRK--------- -----------------------------------------------------------SRDYSKE-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Gasterosteus_aculeatus_ITGA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------IVPRSPAHLSFPFVL--------------------------------------------AVLLP CVLSFNVDQKNGMSFEG-PLEDM-FGYTVQQFENNE---GKWVLIGSPLSGQPAKRTGDVYKCPVG-RGNNT-CVKL-EL P------KNTTVPNLHE-VKENMTMGTTLVTNPNG-GFLACGPQYGYMCGQQQYISGVCANVSESFQILNSVAPA----- ------------------------------------------------------------VQECPKELDIVIVLDGSNSI YP--WSSIIDFLRRFIENIQIGPKLS-QVGIVSYGL---------------------------NVTHRVNLSQ--FDNTR DLLNFVEELPQQTGYK---TMTFLGIDTARK------------------------------------EAFLPE-RGARPG VKKVMVIVTDGESHDS--HNLKKVIKECEEDDIERFGIA-VLGDYNRQNKGSEEVQKFIKEIESISSEPLHDHFFNVSDE VALLTIVDALGSKIF-ALEAT----------------------------------------------------------- -----------TGNFTSSFEMEMSQAGFSAHTSK----DGLLLGAVGAYDWNG--------------------------- -----------------------------------------------------------------TVIMHTAGGTIVPGK TAFYDPETEAG---------------------------------YEGLSGYLG------YDVQSASTQ-DG-----VLYI SGAPRYNHTGR---VVVYRLDA--------ENHVVVSQILKGQ---QIGSYFG-SVLQTVDVDGDSSTDLLLVG---APM YMGTERDE----QGQVYVYELDQGGQ---------FHHTFT-------LKPVNQSCCTAHSAS---CTNKNEPCGARFGT AIAAVSDLNLDGFN---DVAIGAPFEND-------HRGAVYIYHGDKKSLKE---------KFV-QHIPAG----GDGEK MKFFGQSIHGVM-DLNGDGIT-------------------------DVTIGGLGGASLFWSR------------------ ---------------------------------DVAALRANMTFDPVKI------------------------------- ----------------------------------NLQKTQCVHAGRASVCVQMTVCFDYSIKSNNQ---DEKPAAVIRYN LTLDA----LRAKARASFKASDDK-----------------------------SDRRITGSLSITDKERKCVQETFVMSP -------------------------------------------------------------------------------- ---------------------------------------------------RLDFREPLMVSLEFGLA-DEDKGP----- -----------------------------------------------VLDENLPRSINETIPL----VDCGIDERCIADL SLKAEPSVKR-------------------------------------------------------------------MLI RGNKDEIVVKVNIRNSK----------DNAYNTKVTLSFTPHINYAKVEP------------------------------ -------------ETLCTLNNTKVECA-----VGYPF-LGSNVEEHFQVRFDVNP-NHIQEV-----------IQINVTA TSDSEELTSTQHDNAVQISIPVKYEAGLIFSVRP---ADEHIVVKEGEQYATEINDTGA--------------------- IGEEVNISYTVEKSADRASPPVRLTVTYPRLSPRQ-----------------------------NNLLYLTHVTAS--PH VKCDAAR------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------WINPLNIN-PKVISPNPKKETLSVFLLAPQS -------------------------------------------------------------------------------- -------------------------------------------------CENLQCASFSCSIPEAASSQ---VNVTFRLW KPTFIQ---------------------------------------------GEFSNLHMLVNATLRIEGTSLFELTSDSK SRTMKIQVSKETLGG-IPIWIIIISILIGLLILALVIFALWKMG----------------------FFKRK--------- -----------------------------------------------------------TRDFSKE-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Homo_sapiens_ITGA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MGPERTGAAPLPLLLVLALS---------------------------------------QGILN CCLAYNVGLPEAKIFSG-PSSEQ-FGYAVQQFINPK---GNWLLVGSPWSGFPENRMGDVYKCPVDLSTAT--CEKL-NL Q------TSTSIPNVTE-MKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPA----- ------------------------------------------------------------TQPCPSLIDVVVVCDESNSI YP--WDAVKNFLEKFVQGLDIGPTKT-QVGLIQYAN---------------------------NPRVVFNLNT--YKTKE EMIVATSQTSQYGGDL---TNTFGAIQYARK------------------------------------YAYSAA-SGGRRS ATKVMVVVTDGESHDG--SMLKAVIDQCNHDNILRFGIA-VLGYLNRNALD---TKNLIKEIKAIASIPTERYFFNVSDE AALLEKAGTLGEQIF-SIEG------------------------------------------------------------ -----------TVQGGDNFQMEMSQVGFSADYSS--QNDILMLGAVGAFGWSG--------------------------- -----------------------------------------------------------------TIVQKTSHGHLIFPK QAFDQILQDR------------------------------------NHSSYLG------YSVAAISTG-ES-----THFV AGAPRANYTGQ---IVLYSVNE--------NGNITVIQAHRGD---QIGSYFG-SVLCSVDVDKDTITDVLLVG---APM YMSDLKKE----EGRVYLFTIK-----------------------------------EGILGQHQFLEGPEGIENTRFGS AIAALSDINMDGFN---DVIVGSPLENQ-------NSGAVYIYNGHQGTIRT---------KYS-QKILGSDG--AFRSH LQYFGRSLDGYG-DLNGDSIT-------------------------DVSIGAFGQVVQLWSQ------------------ ---------------------------------SIADVAIEASFTPEKI------------------------------- ----------------------------------TLVNKNAQII--------LKLCFSAKFRPTK-----QNNQVAIVYN ITLDADGFSSRVTSRGLFKENNE--------------------------------RCLQKNMVVNQ-AQSCPEHIIYIQ- -------------------------------------------------------------------------------- --------------------------------------------------EPSDVVNSLDLRVDISLE-NPGTSP----- -----------------------------------------------ALEAYSETAKVFSIPFH---KDCGEDGLCISDL VLDV-RQIPAA--------------------------------------------------------------QEQPFIV SNQNKRLTFSVTLKNKR----------ESAYNTGIVVDFSENLFFASFSLP--VDG------------------------ ----------TEVTCQVAASQKSVACD-----VGYPA-LKREQQVTFTINFDFNL-QNLQNQ-----------ASLSFQA LSESQE--ENKADNLVNLKIPLLYDAEIHLTRSTN---INFYEISSDGNVPSIVHSFED--------------------- VGPKFIFSLKVT-TGSVPVSMATVIIHIPQYTKEK-----------------------------NPLMYLTGVQTDKAGD ISCNAD-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------INPLKIGQTSSSVSFKSENFRHTKELN--- -------------------------------------------------------------------------------- -------------------------------------------------CRTASCSNVTCWLKDVHMKGEYFVNVTTRIW NGTFAS---------------------------------------------STFQTVQLTAAAEINTYNPEIYVIED--N TVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLG----------------------FFKRK--------- -----------------------------------------------------------YEKMTKNPDEIDETTELSS-- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Mus_musculus_ITGA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MGPGQAGGALLLRLLMLV-----------------------------------------QGILN -CLAYNVGLPGAKIFSG-PSSEQ-FGYSVQQLTNPQ---GNWLLVGSPWSGFPENRMGDVYKCPVDLPTAT--CEKL-NL Q------NSASISNVTE-IKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPA----- ------------------------------------------------------------VQACPSLVDVVVVCDESNSI YP--WEAVKNFLVKFVTGLDIGPKKT-QVALIQYAN---------------------------EPRIIFNLND--FETKE DMVQATSETRQHGGDL---TNTFRAIEFARD------------------------------------YAYSQT-SGGRPG ATKVMVVVTDGESHDG--SKLKTVIQQCNDDEILRFGIA-VLGYLNRNALD---TKNLIKEIKAIASTPTERYFFNVADE AALLEKAGTLGEQIF-SIEG------------------------------------------------------------ -----------TVQGGDNFQMEMAQVGFSADYAP--QNDILMLGAVGAFDWSG--------------------------- -----------------------------------------------------------------TLVQETSHKPVIFPK QAFDQVLQDR------------------------------------NHSSFLG------YSVAAISTE-DG-----VHFV AGAPRANYTGQ---IVLYSVNK--------QGNVTVIQSHRGD---QIGSYFG-SVLCSVDVDKDTITDVLLVG---APT YMNDLKKE----EGKVYLFTIT-----------------------------------KGILNQHQFLEGPEGTGNARFGS AIAALSDINMDGFN---DVIVGSPVENE-------NSGAVYIYNGHQGTIRT---------KYS-QKILGSNG--AFRRH LQFFGRSLDGYG-DLNGDSIT-------------------------DVSIGALGQVIQLWSQ------------------ ---------------------------------SIADVAIEALFTPDKI------------------------------- ----------------------------------TLLNKDAKIT--------LKLCFRAEFRPAG-----QNNQVAILFN MTLDADGHSSRVTSRGVFRENSE--------------------------------RFLQKNMVVNE-VQKCSEHHISIQ- -------------------------------------------------------------------------------- --------------------------------------------------KPSDVVNPLDLRVDISLE-NPGTSP----- -----------------------------------------------ALEAYSETVKVFSIPFY---KECGSDGICISDL ILDV-QQLPAI--------------------------------------------------------------QTQSFIV SNQNKRLTFSVILKNRG----------ESAYNTVVLAEFSENLFFASFSMP--VDG------------------------ ----------TEVTCEVGSSQKSVTCD-----VGYPA-LKSEQQVTFTINFDFNL-QNLQNQ-----------AAINFQA FSESQE--TNKADNSVSLTIPLLYDAELHLTRSTN---INFYEISSDENAPSVIKSVED--------------------- IGPKFIFSLKVT-AGSAPVSMALVTIHIPQYTKEK-----------------------------NPLLYLTGIQTDQAGD ISCTAE-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------INPLKLPHTAPSVSFKNENFRHTKELD--- -------------------------------------------------------------------------------- -------------------------------------------------CRTTSCSNITCWLKDLHMKAEYFINVTTRVW NRTFAA---------------------------------------------STFQTVQLTAAAEIDTHNPQLFVIEE--N AVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMTAGLWKLG----------------------FFKRQ--------- -----------------------------------------------------------YKKMGQNPDEMDETTELNS-- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Canis_familiaris_ITGA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MRPGRAGGAPLRLLLVLG-----------------------------------------QGILN CCMAYNVGLLEAKIFSG-PSSEQ-FGYAVQQFINPK---GNWLLVGSPWSGFPENRMGDVYKCPIDLSAAT--CEKL-NL E------TATSIPNVTE-MKTNMSLGLTLTRNMGTGGFLTCGPLWAQQCGSQYYATGVCSDVSPDFQILTSFAPA----- ------------------------------------------------------------AQTCPSLIDVVVVCDESNSI YP--WEAVKNFLEKFVQGLDIGPKKT-QVGLIQYAN---------------------------KPRVVFNLNT--FKTKA EMTEATSQTYQYGGDL---TNTFKAIQYAKD------------------------------------FAYAAA-AGGRPG ATKVMVVVTDGESHDG--SMLKAVIDQCNNDNILRFGIA-VLGYLNRNALD---TKNLIKEIKAIASIPTERYFFNVSDE AALLEKAGTLGEQIF-SIEG------------------------------------------------------------ -----------TIQGGDNFQMEMSQVGFSADYSP--QKDILMLGAVGAYGWSG--------------------------- -----------------------------------------------------------------TVVQQTSHGHFIFPK QAFDQILQDK------------------------------------NHSSYLG------YSVAAISTG-KD-----IHFV AGAPRANYTGQ---IVLYSVDE--------NGNVTVIQAHRGD---QIGSYFG-SVLCSVDVNKDTITDVLLVG---APM YMNDLKKE----EGKVYLFTIT-----------------------------------KGVLNWHQFLEGPNGVENARFGS AIAALSDINMDGFN---DVIVGSPLENQ-------NSGAVYIYNGHEGTIRM---------RYS-QKILGSNG--AFRSQ LQYFGRSLDGYG-DLNGDSIT-------------------------DVSIGAFGQVVQLWSQ------------------ ---------------------------------SIADVSVDASFTPDKI------------------------------- ----------------------------------TLFNKNADIT--------LKLCFSAKFRPTK-----QNDQVAIIYN ITIDANLYSSRVTSRGLFKENNE--------------------------------RCLQKNMLISQ-AQSCAEYTINIQ- -------------------------------------------------------------------------------- --------------------------------------------------KPSDVVNSLDLYVNISLE-HPGTSP----- -----------------------------------------------ALEAYSEKAKVFSIPFY---KDCGDDGVCISDL VLNV-QHLSAT--------------------------------------------------------------QDQPFIV SNQNRRLTFSITLKNKR----------ESAYNTRIVVDFSENLFFASWSMP--VDG------------------------ ----------TEVTCQIASSQKTVTCD-----VGYPA-LKREQQVTFTINFDFNL-QNLQNQ-----------ASVSFQA LSESYE--ENKADNLVNFKTPLRYDADIHITRSTN---INFYEVSSDGNVPSIVHSYED--------------------- IGPKFIFSIKVT-TGSVPVSMASVIIHIPQYTKEK-----------------------------NPLMYLTEVHADQAGD ISCNAK-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------INPLKIGHTSPSVYFKNENFRHIKDLN--- -------------------------------------------------------------------------------- -------------------------------------------------CRTASCSNVTCWLKDLQVKGEYFLNVSTRIW NGTFAA---------------------------------------------STFQTVQLTASAEIDTYNPQIYVIEE--N TVTIPITIMKPHEKAEVPTGVIIGSVIAGIILLLALVAVLWKLG----------------------FFKRK--------- -----------------------------------------------------------YEKMSKNADEIDETTELNS-- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Bos_taurus_ITGA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MRPGRTGGTPLQLVLVFS-----------------------------------------QGILN CCVAYNVGLPKAKIFSG-PSSEQ-FGYAVQQFINPK---GNWLLVGSPWSGFPKNRMGDVYKCPVDLSTTT--CEKL-NL Q------TSTSMSNVTE-MKTNMSLGLTLTRNVGTGGFLTCGPLWAQQCGSQYYTTGVCSDVSPDFQLRTSFAPA----- ------------------------------------------------------------VQTCPSFIDVVVVCDESNSI YP--WDAVKNFLEKFVQGLDIGPTKT-QMGLIQYAN---------------------------NPRVVFNLNT--FKSKD EMIKATSQTFQYGGDL---TNTFKAIQYARD------------------------------------TAYSTA-AGGRPG ATKVMVVVTDGESHDG--SKLKAVIDQCNKDNILRFGIA-VLGYLNRNALD---TKNLIKEIKAIASIPTERHFFNVSDE ADLLEKAGTIGEQIF-SIEG------------------------------------------------------------ -----------TVQGGDNFQMEMSQVGFSAEYSP--QNNILMLGAVGAYDWSG--------------------------- -----------------------------------------------------------------TVVQKTPHGHLIFSK QAFEQILQDR------------------------------------NHSSYLG------YSVASISTG-NS-----VHFV AGAPRANYTGQ---IVLYSVNE--------NGNVTVIQSHRGD---QIGSYFG-SVLCAVDVNKDTITDVLLVG---APM YMNDLKKE----EGRVYLFTIT-----------------------------------KGILNWHQFLEGPKGLENARFGS AIAALSDINMDGFN---DVIVGSPLENQ-------NSGAVYIYNGHEGMIRL---------RYS-QKILGSDR--AFSSH LQYFGRSLDGYG-DLNGDSIT-------------------------DVSVGAFGQVVQLWSQ------------------ ---------------------------------SIADVSVDASFTPKKI------------------------------- ----------------------------------TLLNKNAEIK--------LKLCFSAKFRPTN-----QNNQVAIVYN ITIDEDQFSSRVISRGLFKENNE--------------------------------RCLQKTMIVSQ-AQRCSEYIIHIQ- -------------------------------------------------------------------------------- --------------------------------------------------EPSDIISPLNLCMNISLE-NPGTNP----- -----------------------------------------------ALEAYSETVKVFSIPFH---KDCGDDGVCISDL VLNV-QQLPAT--------------------------------------------------------------QQQPFIV SNQNKRLTFSVQLKNKK----------ESAYNTEIVVDFSENLFFASWSMP--VDG------------------------ ----------TEVTCQIASSQKSVTCN-----VGYPA-LKSKQQVTFTINFDFNL-QNLQNQ-----------ASISFRA LSESQE--ENMADNSVNLKLSLLYDAEIHITRSTN---INFYEVSLDGNVSSVVHSFED--------------------- IGPKFIFSIKVT-TGSVPVSMASVIIHIPQYTKDK-----------------------------NPLMYLTGVHTDQAGD ISCEAE-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------INPLKIGQTSSSVSFKSENFRHIKELN--- -------------------------------------------------------------------------------- -------------------------------------------------CRTASCSNIMCWLRDLQVKGEYFLNVSTRIW NGTFAA---------------------------------------------STFQTVQLTAAAEIDTYNPQIYVIEE--N TVTIPLTIMKPHEKVEVPTGVIVGSVIAGILLLLALVAILWKLG----------------------FFKRK--------- -----------------------------------------------------------YEKMAKNPDETDETTELNS-- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------- >Monodelphis_domestica_ITGA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------