>Homo_sapiens-PRKAG2(ENSP_287878) MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRG PQPR--------PSSPMSAPVRPKTSPGSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPATSPGGIRF FSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKH----EPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAP SKAAALAAA--LGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE- >Macaca_mulatta-PRKAG2(ENSMMUP_14355) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------EDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVTNVLLTAYFLSINT----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE- >Mus_musculus-PRKAG2(ENSMUSP_30784) MGSAAMDTKKKKEVSSPGGSSGKKNPSLKRRSLRVHIPDLSSFAMPLLDGDVENSEKHSSRKVDSPFSSGSPSRGLFSRG PQPR--------PSSPVSAPVRPKTSPGSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPSTSPGGIRF FSRSRKTSSVSSSPSTPTQVTKQHPFPLESYKQ----EPERPESRIYASSSPPDTGQRFCLA-FQSPARPPLASPTYHAP LRTAVLAAA--PGPAEAGMLEKLEFQEE--EDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE- >Rattus_norvegicus-PRKAG2(ENSRNOP_12111) --------------------------------------DLSSFAMPLLDGDVENSEKHSSRKVDSPFSSGSPSRGLFSRG PQPR--------PSSPVSAPVRPKMSPGSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPSTSPGGIRF FSRSRKTSSVSSSPSTPTQVTKQHPFPLESYKQ----EPERLESRIYASSSPPDTGQRFCLA-FQSPVRLPLASPTHHAP LRTAALAAA--PGPAEAGMLEKLEFQEE--EDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDELGIGTYHNIAFIHPNTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE- >Pteropus_vampyrus-PRKAG2(ENSPVAP_13679) --------------------------------------DLSSFAMPLLDGDLESSEKHSSRKVDSPFGSGSPSKGFFSRG PQHR--------PSSPVSAPVRPKTSPGSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKESS-PTSNASTSPGGI-L LSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKH----EPERLENRIYASSPPPDTGQRFCPSSFQSSSRPPSASPTHYTP SKTAALAAA--PGPAEAGMLEKFELEEEAAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDLINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLGALGIGTYDNIAFIHPDTP IIKALNVFVERRVSALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSRLELLET IVDRIVRAEV-HRLVVVNDADSIVGIISLSDILQALILTPPGAKQKEPETE- >Bos_taurus-PRKAG2(ENSBTAP_53577) MGSAAMDTKKKKDVCSPGGSGGKKNSSQKRRSQRVHIPDLSSFAMPLLDGDLESSEKPPSRKVDSPFGSGSPSKGFFTRG PQPR--------PSSPVSAPVRPKTSPGSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKDSS-PSSNPSTSPGGIRF FSRSRKTPGLSSSPSTPTQVAKQHTFPLESYKQ----EPERLENRIYASSSPPDTGQRFSPSSFQSAARPPSASPTHPSP SKSAALAAA--PGPAEAGMLEKFELEEEAAEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVHSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDALGIGTYHNIAFIHPDTP IIKALNVFVERRVSALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLEILET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKQTEAE- >Canis_familiaris-PRKAG2(ENSCAFP_7340) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MFKLQQNEQ----IQET--------------------------------------- ------------------------------EDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWRET--ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPK-PAFMKQNLDALGIGTYHNIAFIHPDTP IIKALNVFVERRVSALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLEILET IVDRIVRAEV-HRLVVVNEADSIVGIISLSDILQALILTPAGAKQKEAETE- >Monodelphis_domestica-PRKAG2(ENSMODP_5687) MGSAAMDTKKKKDVSSPGGSSGKKSSGQKRRSLRVHIPDLSSFAMPFLDGDLESSEKHASRKVDSPFSSGSPSKGFFSRG PQHR--------PSSPVSAPVRARNSPGSPKTVFPFPYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPSTSPGGIKF FSRSRKTPGLSSSPSTPTQVIKQHTFPLESYKN----EPERLETRIYASSSPPDTGQRFCLPSFQSSAKPPSAAVAAAAA AAAVAAAAA--PGTAEAGMLEKLELEEEAIEESESDIYMRFMKSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYRS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVSEMPK-PAFMKQNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLET IVDRIVKAEV-HRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKESEAE- >Ornithorhynchus_anatinus-PRKAG2(ENSOANP_9860) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------LLDVSFFAAE------------------------------ ------------------------------EESESDIYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVSEMPK-PAFMKQNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLET IVDRIVKAEV-HRLVVVSEADSIVGIISLSDILQALVLTPAGAKQKEGEAE- >Gallus_gallus-PRKAG2(ENSGALP_10021) MGSTAMDTKKK---DSSGSG--RRGSSQKKLMLRVHIPDLSSFAMPFLDGDVENTDKNASRKVEESYSAGSPSKGIFSKG LQNR--------PSSPVSAPVRSKHSPGSPKTVFPFPYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPSTSPGGIKF FSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKH----EPERLETRIHCSS-PPDTGQRFSLPPSQSAAKPPIMTPSPCAT SKPVSRACPEPSLVQLEAMIMKLTYCSKSLEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPK-PAFMKKNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLET IVDRIVKAEV-HRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE- >Taeniopygia_guttata-PRKAG2(ENSTGUP_615) MGSTAMDKKKD---ASSSSSSTQKSSSHKKLMLRVHIPDLSSFAMPFLDGDVESTDKNASRKVDESYSAGSPSKGLFSKG LQNR--------PSSPVSAPVRSKHSPGSPKTVFPFPYQE--SPPRSPRRMSFSGIFRSSSKESS-PNSNPSTSPGGIKF FSRSRKTSGLSSSPSTPTQVTKQPTFPLESYKH----EPERPETRIHCSS-PPDTGQRFSLPPSQSAAKPPIMTPAPCAT SKPVSKACVQFATGKCAGLCVDCVLCYSSLEESESDIYVRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIS PDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFMSEMPK-PAFMKKNLDELGIGTYHNIAFIHPDTP IIKALNIFVERRISALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALQHRSQYFEGVVKCSMLETLET IVDRIVKAEV-HRLVVVNEADSIVGIISLSDILQALVLTPAGAKQKENESE- >Xenopus_tropicalis-PRKAG2(ENSXETP_21429) --------------------------------------DLSSFAMPFLDGDLDNAEKNSQRKAEEPCSTGSPSKSFFPRG LQNQ--------PSSPLSAPVKTKYSPGSPKTVFPFPYQE--SPPRSPRRMSFSGIFRSSSKDSSSPNSNPSTSPGGIRF FTRSRKASGLSSSPSTPTQVTKQPTFPLESYKH----EPERLEARLRSYSSPPDTGQRFSLPHMPVTVTKSSVLSSSLSA TSRTAQSTT-------EGMLEKLELEDEAVEESESDIYTRFMKSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWETKNQSFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVNIF PDASLFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVSEMPK-PAFMKQNLEELGIGTYHNIAFIHPHTP IIKALNIFVERRVSALPVVGESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALEHRSQYFEGVVKCSKLETLET IVDRIVKAEV-HRLVVVDEADSIVGIISLSDILQALVLSPAGAKRKESEAE- >Oryzias_latipes-PRKAG2(ENSORLP_20994) ----------MGSTVMDSNKQSSKKTPKRRRSLRINMPDFGAFTASP----AAETGSSSKSGTQTSRKLDSFFYETSPTK GAFARSPVS--VPPTPLSAPVQSKPISTSPKTIFPYPSNQNSSSPKSPRRLSFSGIFRSNSTAAS-QNINPKRKVTGSFF YTLKITPSGLSTPPTTPVQASSQPVFPQEAQQSTSSHESLEPGSRVRSLSSTLDTGQRVNLPSAKPPVSSATPMPHYSTS QHS-AWPGPV-----SAGMLEKLELDDDAAE-PESDIYMRFMKSHKCYDIVPTSSKLVVFDTALQVKKAFFALVANGVRA APLWDTEKQSFV------------GMLTITDFIIILHRYYKS--PMVQIYELEEHKLETWR----EVYLQATFKPLVNIS PDASLFDAVYTLIKNKIHRLPVIDPVTGNALYILTHKRILKFLQLFMYEMPK-PAFMKQTLSELGIGTYHDIAYIHPDTP IIKALNIFVEKRVSALPVVDDSG-TVVDIYSKFDVIN----LAAEKTYNNLDITVTQALKHRSQYFEGVVKCHKMETMEA IVDRIVKAEV-HRLVVVDERSGIQGIVSLSDILQALVLSPADINKEENVTE- >Gasterosteus_aculeatus-PRKAG2(ENSGACP_17670) ----------MGSTVMESSKDPSKNRPKRRRSLRINMPDFGAFSSPQ-----ADTSGSTKSGAQTG---EPRVRSASPTG VASARRPAGAPLVPGSRSAPVQLKAGSSAPKTIFPYPSHQ-DSPPKSPRRLSFSGIFRSSSCSTP-ASIK---------I FSRTRRASGLSTPPSTPTQACSPPVFTQEAQASGPRPERLEAVARSRSISTPPDTGQRPGLPSARPPIACSSPVPSPPSQ QQR--KVRGP-----FEGMLEKLQLDDDAAAEPESDIYMRFMKSHKCYDIVPTSSKLVVFDTALQVKKAFFALVANGVRA APLWDTEKQSFV------------GMLTITDFIIILHRYYKS--PMVQIYELEEHKLETWRA---EVYLQATFKPLVNIS PDASLFDAVYTLIKNKIHRLPVIDPVTGNALYILTHKRILKFLQLFMCEMPK-PAFMKQTLGELGIGSYHNIAFIHPNTP IIKALNIFVERRVSALPVVDESG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALKHRSQYFEGVMKCHKTETMKT IVDRIVKAEV-HRLVVVDAHSSIEGIVSLSDILQALVLGPAGIDAQ------ >Takifugu_rubripes-PRKAG2(ENSTRUP_13041) ----------MGSTLMESGKS-SKKMPKKRRSLRINMPNLGALLCFCRTVILASTYQESQHNPQEI---DFPSQSASPSR AGCALSPV--LVAPCPQSAPVHSKTSSGSPKTIFPYPSPH-TSSPKSPRRLSFSGIFRSSSSCSS-TSIK---------L FSRTRRASGFSTPPNTPTQSCSQPVFTQEAQPSTADAENPDASTRSRSMSTPPDIGQRLTLPAAKPPIPSSSPAPSHSTS HDTAAAAAAN-----GAGMLEKLDLDDDAAE-PESDIYMRFMKSHKCYDIVPTSSKLVVFDTALQVKKAFFALVANGVRA APLWDTEKQSFV------------GMLTITDFIIILHRYYKS--PMVQIYELEEHKLETWR----EVYLPAAFKPLVNIS PDASLFDAVYTLIKNKIHRLPVIDPVTGNALYILTHKRILKFLQLFMCEMPK-PAFMKHTLKELGIGTYRDIAFIHPNTP IIKALNIFVERRVSALPVVDGCG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALKHRSQYFEGVVKCHKMETMET IVDRIVKAEV-HRLVVVDEHSSIEGIVSLSDILQALVLSPAG---------- >Tetraodon_nigroviridis-PRKAG2(ENSTNIP_18286) -------------------------------------------------------------------------------- ------------PPCSQSAPVHSKTTSVSPKTIFPYPSHQ-TSSPKSPRRLSFSGIFRSSSSCSS-TSIK---------L FSRTRRASGFSTPPNTPTQSCSQPVFTQEAQPSTPVAANPDASPRSRSMSTPPDIGQRLSLPSIRPSIPPSNHGPSHSTS -----QVCSL-----FEGMLEKLELDDDAAE-PESDIYMRFMKSHKCYDIVPTSSKLVVFDTALQVKKAFFALVANGVRA APLWDTEKQSFV------------GMLTITDFIIILHRYYKS--PMVQIYELEEHKLETWR----EVYLPAAFKPLVNIS PDASLFDAVYTLIKNKIHRLPVIDPVTGNALYILTHKRILKFLQLFMCEMPK-PAFMKQTLRELGIGTYRDIAFIHPDTP IIKALNIFVERRVSALPVVDDSG-KVVDIYSKFDVIN----LAAEKTYNNLDITVTQALKHRSQYFEGVMKCHKTETMET IVDRIVKAEV-HRLVVVDQHSNIEGIVSLSDILQALVLSPAG---------- >Gasterosteus_aculeatus-PRKAG2(ENSGACP_7439) --------------------------------------DRTVFAMPFLEGDDDRAEKDSNRKLEAPFLSTSPPLSFFQRA PFRR--------PSSPCSTRARTSSFNVNPGHPKTVFLNQIGPPQLESPPKTPRSRLSFSGIFRSTSRDSKPQPVSIKLF TCNKQDKAREYHHPHTPQNLSAFPLEMYQEEPR-------RLETRLRSFSSPPNTKQCSCSSCLQLPAVAPPLPVRRLVS AASAAFPSVG--GSMSEQLDPED----PASEESERDIYMRFMKCHKCYDLIPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILTRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVHIS PGASIFEAVHSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVCEMPM-PAFMKQTLEDLSVGTYDNIAFIHPHTP LITALSVFTLRRVSALPVVDHHG-RVVDIYSKFDVIN----LAAEKTYNNLDLTVTQALRHRSQYFEGVMKCNKLETLDT IVDRIVKAEV-HRLVVVDEDSRIVGIVSLSDILQALVLTPAAGLRRKESLPS >Tetraodon_nigroviridis-PRKAG2(ENSTNIP_16537) ---------------------------------------------------------RPQEGRRRDVLRPAEDRGQTQGQ RSAP--------ARRSAGAHLSPPS----------------PAHSLSPPPPLPPA-FQLET------------------Y LSEPQR-------LQTRR---------------------------LRSFSSPADAALFVIN-----NISAARAPLSSITH NNNKATAALG--VVISPTGAFKELKLSTGSGESERDIYMRFMKCHKCYDIIPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILTRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVHIS PDASVFDAVHSLIKQRIHRLPVIDPISGNALYILTHKRILKFLQLFVCEMPM-PAFMKQTLEELAVGTYANIAYIQPDTP LITALSVFTHRRVSALPVVDHSG-KVVDIYSKFDVIN----LAAEKTYNNLDVTVTQALQHRSQYFEGVMKCNKLETLET IVDRIVKAEV-HRLVVVDEESRIVGIVSLSDILQALVLTPAGGWDLETELQ- >Oryzias_latipes-PRKAG2(ENSORLP_4914) ---------------------------------------------------------------PAPPSSREEDVVFQLQT YLSE--------PQRPESRRLRS----------------------FSSPP-DPGQRFALP-----TST-----------F ACCQQP-------PQAPP-----------------------------THASPPISIQPGFR-----AAVIP----SKLPK QAGAADG-------MTEQQDLDD----AVSEESERDIYMRFMKCHKCYDIIPTSSKLVVFDTTLQVKKAFFALGANGVRA APLWESKKQSFV------------GMLTITDFINILTRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVHIP PDASIFEAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFVCEMPM-PAFMKQSLQQLGVGTYSNIAYIHPDTP LITALSVFTHRRVSALPVVDHNG-RVVDIYSKFDVIN----LAAEKTYNNLDVTVTQALRHRSQYFEGVMKCNRLETLET IVDRIVKAEV-HRLVVVDEDSRIVGIVSLSDILQALVLTPAG---------- >Takifugu_rubripes-PRKAG2(ENSTRUP_44823) -----------------------------------------------------------MKRLSSLMLRKWKEKERWSGR RRSE--------PYGAEGGAVS--------------------SVSLTPPSVLSLAPLPLET------------------Y LSEPQR-------LETRR---------------------------LRSFSSPADAHLSSSS-----SACIPPALPHLLWV QVFRAAP--------PPAPASERHMCLAGSGGSERDIYMRFMKCHKCYDIIPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWESKKQSFV------------GMLTITDFINILTRYYKS--PMVQIYELEEHKIETWR----ELYLQETFKPLVHIA PSASIFDAVYSLIKNKIHRLPVIDPVSGNALYILTHKRILKFLQLFVCEMPM-PAFMKKPLEELAVGTYSNIAYIHPDTP LITALSVFTHRRVSALPVVDHSG-KVVDIYSKFDVIN----LAAEKTYNNLDVTVTQALRHRSQY-EGVMKCNKLETLET IVDRIVKAEVVHRLVVVDEESHIVGIVSLSDILQALVLTPAGASPLLVLHH- >Branchiostoma_floridae-PRKAG2(XP_002606213) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------ADDAVYLNFMRSHHIYDIIPTSSKLVVFDTQLLVKKAFFALVYNGIRA APLWDSRTQNFV------------GMLTITDFINVLQKYYKS--PLVQMDELEEHKIATWR-----EVLGLTNRPLVSID PDETLFEGIKRLIGCKIHRLPVIDETTGNAIYVLTHKRILKFLWLYLKDIPK-PDYMNNTLEELGIGTYSNIATASPETH LIHALHIFVERRVSALPVVDSDG-KVVDIYAKFDAIN----LAAEKTYNNLDITIRQALQHRSQGFEGVHRCLKTETLDT ICDRVVKAEV-HRLVVVDTDDCVVGVVSLSDILKFLVLKPAG---------- >Strongylocentrotus_purpuratus-PRKAG2(XP_001196977) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------MATTEEEDMTFVRFMKNHKCYEIIPTSSKLVVFDAELLVKKAFYALVYNGVRA APLWDSSKQDFV------------GMLTITDFINILQYYYKS--PLVKMDELEEHKIATWR-----EVLKEKARPLVWIN PDQSLFEAVKMLIQQKIHRLPVIDNATGNVIYILTHKRILKFLAL-LTEIKS-PSFLKKTLKELNIGTYTNIATARPDTP LITALNMFINKRVSALPIVDENN-KIVDIYAKFDVIN----LAAEKTYNNLDITIQQALQFRQTYFEGVSTCKASETLET IMERIIKAGV-HRLVVTDDEKHVIGVISLSDILNSLVLKPA----------- >Danio_rerio-PRKAG1(ENSDARP_16733) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------MECLPAVLDDLDC KKEA----------------------HIEDPEFN--VYTRFMKSHRCYDLVPTSSKLVVFDTSLQVKKAFFALVSNGVRA APLWDSKKQCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EVYLQDSFKPLVSIS PNASLYDAVSSLLKHKIHRLPVIDPLTGNALYILTHKRILKFLKLFISEIPK-PAFLSQTLEELNIGTFDNIAVVHSDTP LYAALGIFVEQRVSALPVVDENG-RVVDIYSKFDVIN----LAAEKTYNNLDITVTKALQHRSQYFEGVLTCRASETLQA IINRLVEAEV-HRLVIVDEQEVVKGIVSLSDILQALVLTSGDDGSA------ >Gasterosteus_aculeatus-PRKAG1(ENSGACP_939) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------MECIPVAMDDLEG KKDP----------------------IIEDPEHN--VYTRFMKSHRCYDLVPTSSKLVVFDTSLQVKKAFFALVSNGVRA APLWDSKKQCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----ELYLQDSFKPLVSIS PNASLYDAVSSLLKNKIHRLPVIDPLTGNTLYILTHKRILKFLKLFISEMPK-PSFLRQTLEDLNIGTFRNIAVVRSDTP LYTALGIFVEQRVSALPVVDDKG-RVVDIYSKFDVIN----LAAEKTYNNLDLTVTKALKHRSQYFEGVLTCNRHETLEA IINRLVEAEV-HRLVVVDEQDVVKGIVSLSDILQALVLTDGEEGKYNLVT-- >Takifugu_rubripes-PRKAG1(ENSTRUP_31172) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------MECIPATIEDLEG KKDF----------------------VHEDPEHN--VYTRFMKSHRCYDLVPTSSKLVVFDTSLQVKKAFFALVSNGVRA APLWDSKKQCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PSASLYDAVSSLLKNKIHRLPVIDPLTGNTLYILTHKRILKFLKLFISEMPK-PSFLSQSIGELNIGTFQNIAVVRADTP LYTALGIFVEQRVSALPVVDDRG-RVVDIYSKFDVIN----LAAEKTYNNLDVTVTKALQHRSQYFEGVLTCNRHETLET IINRLVDAEV-HRLVVVDEQEVVKGIVSLSDILQALVLTDGDAGESSRSSAA >Tetraodon_nigroviridis-PRKAG1(ENSTNIP_17618) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------MKSHRCYDLVPTSSKLVVFDTSLQVKKAFFALVSNGVRA APLWDSKKQCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PSASLYDAVSSLLKNKIHRLPVIDPLTGNTLYILTHKRILKFLKLFISEMPK-PSFLSQSIGELNIGTFQHIAVVRADTP LYTALGIFVEQRVSALPVVDDRG-RVVDIYSKFDVIN----LAAEKTYNNLDVTVTKALQHRSQYFEGVLTCNRDDTLET IINRLVEAEV-HRLVVVDEQEVVRGIVSLSDILQALVLTD--AGTA------ >Oryzias_latipes-PRKAG1(ENSORLP_1994) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------MDCIPVTIDDLEG KKDP----------------------VIEDSEHN--AYTRFMKSHRCYDLVPTSSKLVVFDTSLQVKKAFFALVSNGVRA APLWDSKKQCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----ELYLQDSFKPLVSIS PNASLYDAVSSLLRNKIHRLPVIDPLTGNTLYILTHKRILKFLKLFISEMPR-PSFLSKTVEELNIGTFKNIAMVRKDTP VYTALGIFVEQRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVTVTKALQHRSQYFEGVLTCHIHDTLEA IINRLVEAEV-HRLVVVDEQEVVKGIVSLSDILQALVLTNKEECKY------ >Xenopus_tropicalis-PRKAG1(ENSXETP_24423) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------GSVMIESNMQE KCEP----------------------ASDVLESDSGVYTRFMKNHKCYDLIPISSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQGFV------------GMLTITDFINILHRYYKS--PMVQIYELEEHKIETWR----ELYLQDSFKPLVSIS PSASLFDAVSSLIKNRIHRLPVISPDSGNTLYILTHKRILKFLKLFMSEVEK-PAFVTKSLKDLHIGTYENIALVRPDTP VYVALGIFVQRRVSALPVVDDSG-RVVDIYSKFDVIN----LAAEKTYNNLDITVTKALGHRSHYFEGVLKCYQHETLET IINRLVEAEV-HRLVVVDENDVAKGIVSLSDILQCLVLTAGGEKSLI----- >Monodelphis_domestica-PRKAG1(ENSMODP_19616) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------SRAHSSRDEGEIL IPSC----------------------SAETPESNSAVYTCFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFVVSI---WLP---GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPDSGNTLYILTHKRILKFLKLFIAEFPK-PEFMSKSLKELQIGTYANIALVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDISVTKALQHRSHYFEGVLKCYQHETLET IINRLVEAEV-HRLVVVEENNVVKGIVSLSDILQALVLT-GGEKP------- >Dasypus_novemcinctus-PRKAG1(ENSDNOG_5136) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------TPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMAQSLEELRIGTYANIALVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENNVVKGIVSLSDVLQALVLR-GGEKQP------ >Oryctolagus_cuniculus-PRKAG1(ENSOCUP_7265) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------LVQVTASDSCSAV KNEH----------------------SQDTPDSNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMTKSLQELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDESNVVKGIVSLSDILQALVLT-GGEKP------- >Loxodonta_africana-PRKAG1(ENSLAFP_4217) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------YAETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIAEFPK-PEFMCKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKKP------ >Mus_musculus-PRKAG1(ENSMUSP_132499) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------MESVAAESSPAL ENEH----------------------FQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLQELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDEHDVVKGIVSLSDILQALVLT-GGEKKP------ >Rattus_norvegicus-PRKAG1(ENSRNOP_20093) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------------MESVAAESAPAP ENEH----------------------SQETPESNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEA IINRLVEAEV-HRLVVVDEHDVVKGIVSLSDILQALVLT-GGEKKP------ >Macaca_mulatta-PRKAG1(ENSMMUP_20637) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------METVISSDSSPAL ENEH----------------------PQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFVVLR---ALSCPLGMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKKP------ >Canis_familiaris-PRKAG1(ENSCAFP_12869) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------QVTSSDSSSAL ENEH----------------------PQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKL------- >Myotis_lucifugus-PRKAG1(ENSMLUP_10167) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------METVISSDNSPAL ENEY----------------------PQETPESNNTVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKP------- >Homo_sapiens-PRKAG1(ENSP_323867) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------METVISSDSSPAV ENEH----------------------PQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKKP------ >Bos_taurus-PRKAG1(ENSBTAP_43459) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------MEKVPSSDSYPAV ENEH----------------------LQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRA APLWDSKKQSFV------------GMLTITDFINILHRYYKS--ALVQIYELEEHKIETWR----EVYLQDSFKPLVCIS PNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPK-PEFMSKSLEELQIGTYANIAMVRTTTP VYVALGIFVQHRVSALPVVDEKG-RVVDIYSKFDVIN----LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLET IINRLVEAEV-HRLVVVDENDVVKGIVSLSDILQALVLT-GGEKP------- >Takifugu_rubripes-PRKAG3(ENSTRUP_18884) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------EDDVLSMESGGVCTYAPP P---------------------------LEPDPDIFIYMNFMKSHTCYDAIPTSSKLVIFDTTLQVKKAFFALVANGVRA APLWDNKLKCFVDIS-AAECILTRGMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EIYLEYSTNRLISIT PDCSLFDAIYSLLKNKIHRLPIIDPISGDVLHILTHKRILKFLHIFGSMIPK-PRFLQKQIGEVAIGTFRQIATVHESAS VHDALMIFVERRVSALPVVNEEG-KVVALYSRFDVIN----LAAQKTYNNLNMTMREAIASRACCVEGVLKCYHHETLET IIDRIAKAEV-HRLVLVDSEDVVRGIVSLSDLLQALVLTPAGIDA------- >Tetraodon_nigroviridis-PRKAG3(ENSTNIP_18721) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------FVGVCTHARP PPGS-----------------------PAEPDPDTFIYMNFMKSHTCYDAIPTSSKLVIFDTTLQVKKAFFALVANGLRA APLWDNKLKCFV------------GMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EIYLEYSTNKLISIT PECSLFDAIYSLLKNKIHRLPIIDPVSGDVLHILTHKRILKFLHIFGSMIPK-PRFLQRQIGDVAIGTFRQVATVQESAS VYDALMIFVERRVSALPVVNKEG-TLLDLCLHFRNNN----LAAQKTYNNLNMTMREAIASRACCVEGVLKCYRHETLET IIDRIAKAEV-HRLVLVDSEDVVRGIVSLSDLLQALVLTPAGIDA------- >Gasterosteus_aculeatus-PRKAG3(ENSGACP_11081) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------MEPLAEVPLFEMDEEEDVLSMKSTGGCAYGAR ALAP-----------------------PAGVDSDAFIYMNFMKSHCCYDAMPTSSKLVIFDTTLQVKKAFFALVANGVRA APLWDNKLKRFVG-----------NATLYTDFINILHRYYKS--PLVQIYELEEHKIETWR----EIYLQYSINTLISIT PDCSLFDAIYSLLKNKIHRLPVIDPASGNVLHILTHKRILKFLHIFRSKIPK-PGFLQKRIHEVEIGTFKQIATVQESAS VFDALTVFVERRVSALPVVSERGGKVVALYSRFDVIN----LAAQKNYNNLNMTMREAVSSRACCVEGVLKCYPHETLET IIDRIAKAEV-HRLVLVDADDVVRGIVSLSDLLQALVLTPADIHEGSRGRD- >Oryzias_latipes-PRKAG3(ENSORLP_22813) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------------------VSAEASTYASH PVAP-----------------------PADADPDTFIYMNFMKRHCCYDAIPTSSKLVIFDTMLQVKKAFFALVANSVRA APLWDSKLQCFVG---FRRLRVLAGMLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----EIYLQYSNNRLISIT PESSLFDAIYSLLKNKIHRLPVIDPTSGNVLHILTHKRILKFLHIFGSMIPK-PRFLQKSISEVPIGTFKQIATVQESAT VYQALSIFVERRVSALPVVNEQD-KVVALYSRFDVIN----LAAQKNYNNLNITMREAIACRSCWMEGVLKCYPHETLET IIDRIAKAEV-HRLVLVDSNDVVRGIVSLSDLLQALVLSPAGKPP------- >Danio_rerio-PRKAG3(ENSDARP_2296) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------MDPLTEFPFMEDEGLTMKRTG PLQ----------------------------DPDADVYAKFFMSHCCYDAIPTSSKLVVFDTTLQVKKAFFALVANGVRA APLWDDKLQCFVG------------MLTITDFINILHRYYKS--PLVQIYELEEHKIETWR----ETYLQYSVTSLISIA PDSSLFEAIYSLLKNKIHRLPVIDPETGNVLHILTHKRILKFLHIFGSMIPK-PRFLQKRIEEVEIGTFKSIATVKETET VYDALTIFVERRVSALPVVNEQG-KVVALYSRFDVIN----LAAQKTYNHLNMTMAEAIQGRWCCIEGVLKCYPHETLET VIDRIAEAEV-HRLVLVDTEDVVRGIVSLSDLLQALVLTPAGVEALFS---- >Danio_rerio-PRKAG3(ENSDARP_112412) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MRTEELDRAHAQMDTGTQDDCHED CLVN-----------------------ITDLDPNAETYMNFMKKHCCYDAIPTSCKLVIFDTTLQVKKAFFALVANGLRA APLWDHKLQRFV------------GMLTITDFINILHRYYRS--PMVQIYELEEHKIETWR----DVYLQYQDQCLISIT PDASLFDAVYSLLKHKIHRLPVIDPESGNVLHILTHKRILKFLHIFGTTVPK-PRFLKMQIKEAGIGTFRDVATVSQTAT VYDALSVFVERRVSALPVVDDDG-KVVALYSRFDVIN----LAAQKTYNNLSMSMQEAVRRRRCYVEGVIKCYPDETLET VIDRIVKAEV-HRLVLVDREDVVRGIISLSDLLQAIVLSPAGIDALFS---- >Gasterosteus_aculeatus-PRKAG3(ENSGACP_19964) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------LLATLQVNEG--------------- ----------------------------FLTEHDAAVYMDFMRSHSCYDAIPTSCKLVIFDTKLPVKKAFLALVANGLRA APLWDSKLQRFV------------GMLTITDFINILHYYYRS--PMVQMYELESHKIETWR----DVYLQSSNRILISIS PEASLFDAVYSLLKYKIHRLPVIDPESGNVLHILTHKRILKFLHIFWRKIPK-PAFMRRQIQELGIGTFKNIATVQQTAT LYDALAIFVERRVSALPVVDEQG-KVVSLYSRFDVIN----LAAQKSYNNLDVPMRDAVNGRSCFVEGVIKCYPYETLET IVDRIVHAEV-HRLVLVDRANVVKGIVSLSDLLQSMVLTPAGVDALLS---- >Oryzias_latipes-PRKAG3(ENSORLP_6691) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------EEE----------------- -------------------------------EEDAAVYMNFMKRHRCYDAIPVSCKLVIFDTTLQVKTAFFALVTNGLRA APLWDSKLQRFVAITFFFLYVAAAGMLTITDFINILHCYYKS--PLVQMYGLESHKIETWR----DVYLCYSSQFLVSVS PEASLFDAIYSLLRYKIHRLPVIDPESGNVLHILTHKRILKFLHIFGKKLPR-PGFIRRPIQELGIGTFSNIATVQQTST LYDALSIFVERRVSALPVVDGHG-KVVALYSRFDVIVPPQNLAAQKTYNNLDMTMQEAVRRRTCHVEGVIKCYPHETLET ILDRIVKAEV-HRLVLVDTADVVKGIVSLSDLLQAMVLTPAGIDA------- >Tetraodon_nigroviridis-PRKAG3(ENSTNIP_17552) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------RTDLPS----------------- -------------------------------EADASVYMNFMKSHCCYDAVPVSCKLVIFDTQLQVKKAFFALVANGLRA ALLWDSKLQTFV------------GMLTITDFINILHCYYQSFPPKVQMYELESHKIETWR----DVYLQWSRRVLISIS PQASLFDAVYSLLKHKIHRLPVIDPESGNVLHILTHKRILRFLHIFGKQIPK-PAFTGKPIQDLAIGTFSNVATVQETAT LYDALSIFVERRVSALPVVDEQG-KVVALYSRFDVIN----LAAQRTYNHLDMTMQEAVRRRTGFVEGVIKCYPEETLDT VIERIVEAEV-HRLVLVDVADVVKGIISLSDLLQAMVLSPAGIDVL------ >Gallus_gallus-PRKAG3(ENSGALP_37439) -------------------------------------------------------------------------------- ------------------------------MEQLSSPAAPQMVLLDAAAR----------------PVEEG--------- -------------VPTGFPEA---------------------------LHPRGEEEEEEKRKGSGPVTFTLGNEILGLEP D--------------------------NNFQSPDAEVYMHFMRSHCCYDAVPTSCKLVVFDTTLEIKKAFVALVANGVRA APLWDSKMQSFV------------GMLTITDFINILHRYYRS--PLVQIYEVEEHKIETWR----EVYLQGSFKPLVYIS PSDSLFDAVYSLIKHKIHRLPVIEPISGNVLHILTHKRILKFLHIFG-STIPKPRFLKKTVQELCVGTFRDVAVVPENAP VYAALEIFVDRRVSALPVVNAAG-QVVGLYSRFDVIH----LAAQKTYNNLDISVREALRQRTVCLEGVLTCYPHETMED IIDRIAEEQV-HRLVLVDENRYPRGIVSLSDILQALVLTPAGIDALNS---- >Taeniopygia_guttata-PRKAG3(ENSTGUP_5794) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------LPAGFPKA---------------------------VCPREEEEEEEEYRR--PVTFTLGNEILGLGS E--------------------------TEFQTPDAEVYMHFLRSHCCYDAIPTSCKLVVFDISLEIKKAFLALVANGVRA APLWNSKTQSFV------------GMLTITDFINILHRYYRS--PLVQIYEVEEHKIETWR----EVYLQGSLQPLVYIS PSNSLFDAVYSLIKHKIHRLPVIEPVSGNVLHILTHKRILKFLHIFA-SSIPKPRFLKKTVQELCIGTFRDLAVVAETAP IYTALEIFVDRRVSALPVINDAG-QVVGLYSRFDVIH----LAAQKTYNNLDISVREALRQRTVCLEGVLTCYPHEPMED IIDRIAKEQV-HRLVLVDENQYPRGIVSLSDILQALVLTPAGIDALNS---- >Monodelphis_domestica-PRKAG3(ENSMODP_19188) -------------------------------------------------------------------------------- ------------------------HTELNYS--GDSPSRLLPCMNTTPEKSCEDRGAKASRWTRQEAMEESDPPILEEED SPQSKEWAGPLPQSVSTTSEAGSLGQVAAFPGSDS--IDWGLEAIDLDSTTMCPGLTSIPSGAISLEPETLSIRKEGESP ERATRSPSPQ--------VLLPKLGWDGELLRPGAQIYMHFMQEHNCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRA APLWDSQKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHTIQTWR----EIYLQGSFKPLVSIS PNDSLFEAVYSLIKNRIHRLPVLDPASGNVLHILTHKRLLKFLHIFG-ALLPKPQFLSRSIQDLGIGTFRDLAVVLDTAP ILSALDIFVDRRVSALPVVNESG-QVVGLYSRFDVIH----LAAQKTYNHLDMSVAEALRQRSLCLEGIISCQPHESLGD VIDRIAREQV-HRLVMVDESQHLLGVISLSDILQALVLSPAGIDALGA---- >Pteropus_vampyrus-PRKAG3(ENSPVAP_16195) ---------------------------------------------------------MEP-ELEHALR------------ ------------RTPFWSRP-VDEHQEMSFLEQGDSTSWPSPAMTTSSERSHGKWGDKASRWTRQEAVEEEEEPDLGE-- GLQSR-PAAESIGLEATFPKAIPLAQSATLAGMDAPLTEWDLLSPECTDSAAGSSMDDLELGKEFPATAICSYELG-LME ERPALCPSPQ--------APFTKQGWDDELQKPGAQVYMHFMQKH-CYDAMATSSKLVIFDTTLEIKKAFFALVANGVRA APLWDNKKQSFV------------GMLTITDFILVLQRYYRS--PLVQIYEVEEHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLYIITHKRLLKFLHIFG-ALLPRPSFISRTIQDLGIGTFRDLAVVLETAP VLTALDIFVDRRVSALPVINETG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVAEALRQRTLCMEGVLSCQPEESLEE VINRIVREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGLDTLNA---- >Mus_musculus-PRKAG3(ENSMUSP_80342) ---------------------------------------------------------MEP-ELEHTLP------------ ------------GTLTWSHSGGPESQEMDFLEQGE-NSWPSPAVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGE-- GAQSR-PAAESTRQEATFPKATPLAQAVPLAEAETSPTGWDLLLPDCAASAGGSSTGDLELTIEFPAPEAWDCELEGLGK DRPRPGPSPQ--------APLLGLSWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYALIKNRIHRLPVLDPVSGTVLYILTHKRLLKFLHIFG-ALLPRPSFLCRTIQDLGIGTFRDLAVVLETAP VLTALDIFVDRRVSALPVVNESG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALSA---- >Rattus_norvegicus-PRKAG3(ENSRNOP_23365) ---------------------------------------------------------MEP-ELEHTLP------------ ------------GTLTWSHSGGPESQEMDFLEPEE-NSWPSPTVATSSERTCAIRGVKASRWTRQEAVEEAEPPGLGE-- GAQSG-PAAESTRQKATFPKATPLAQAVPLADAETSTTGWDLFLPDCAASAVGSSTGDLELTIEFPGPEVWDCELKGLEQ DRPRPCPSPQ--------APLLSLSWDDELQKPGAQIYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFAMVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWRGFSAEIYLQGCFKPLVSIS PNDSLFEAVYALIKNRIHRLPVLDPVSGTVLYILTHKRLLKFLHIFG-ALLPRPSFLCRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVVNESG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALSA---- >Oryctolagus_cuniculus-PRKAG3(ENSOCUP_2935) ---------------------------------------------------------MEP-ELEPALR------------ ------------RIPSWSSLGGPEPQEISFLEERDGDSWPSPAVTTSSERLCGKRGTKASRWTKQEAVEKGEPPGVGE-- GPRAR-PAAESTGPEATFPESTPLA------GVGTPAAGWDCQPPDCAASAAGSGTDDGELAAAFPASEDWGCELEGMVE ERPAPCPSPQ--------APLLSLGWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWR----EIYLQGCFKPLVSIS PSDSLFEAVYTLIKNRIHRLPVLDPVSGTVLYILTHKRLLKFLHIFG-TLLPRPSFLCRTIQDLGIGTFRDLAVVLETAP VLTALDIFVDRRVSALPVINESG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTVCLEGVLSCQPHETLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Loxodonta_africana-PRKAG3(ENSLAFP_13401) ---------------------------------------------------------SPPHQTYFS-------------- -----------PQTPSWSRLGEPDHREMSFLGQGDSASWSSPTMTTRSERTCGKQGAKASKWTRQEVVEEGELPGLGK-- GFRSR-PAAESTKPEATFPKATPLAQAAPLACPGTPPTGWDLLPPGCAISAGGSSTDDLALNIEFPATPDGGYELERLVE DRPSPCSSPK--------FLLPKMGWDDELRKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWR----EIYLQGCFKPLVSIS PNDSLLEAVYVLIKNRIHRLPVLDPVSGTVLHILTHKRLLKFLHIFG-TLLPPPSFLSRTIQDLGIGTFRDLAVVLETAP LLTALDIFVDRRVSALPVINESG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTQCLEGVLSCQPHESFGE VIDRIVREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Bos_taurus-PRKAG3(ENSBTAP_17940) ---------------------------------------------------------MEPAELEHALCGS---------- --------LFSTQTPSWSSFGGPEHQEMSFLEQGDSTSWPSPAMTTSAEISLGEQRTKVSRWKSQEDVEERELPGLEG-- GPQSR-AAAESTGLEATFPKATPLAQATPLSAVGTPTTERDSLPADCTASASSSSTDDLDQGIEFSAPAAWGDELG-LVE ERPAQCPSPQ--------VPVLRLGWDDELRKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTMLQIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWR----EIYLQGCFKPLVSIS PSDSLFEAVYTLIKNRIHRLPVLDPVSGAVLHILTHKRLLKFLHIFQRTLLPRPSFLYRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVINEAG-QVVGLYSRFDVIH----LAAQQTYNHLDISVGEALRRRTLCLEGVLSCQPHETLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Canis_familiaris-PRKAG3(ENSCAFP_7343) ---------------------------------------------------------VRVGRMEHTLRRVGGCLRGWVHA HAGLPGRGPTCGSNPSWSSLGGPEHQEMSFLEQGESTSWPSPAMTTGSERSHGKQGAKSSRWTRQEVVKEGELQGLEE-- DPQAR-PPAECTGLEATFPKATHLLQAAPLARVGTPPTEWDISPLNHAASAVGSSPDDLELDIEFPVTADWGYELG-LVE ERPTLCPSPR--------ALLPRPGWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDITLEIKKAFFALVANGIRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEQHTIETWR----EIYLQGCFKPLVSIS PNSSLFEAVYALIKNRIHRLPVLDPVSGAVLHILTHKRLLKFLHIFG-TLLPQPSFLSRTIQDLGIGTFRDLAVVLDTAP ILMALDIFVDRRVSALPVVNETG-QVVGLYSRFDVIH----LAAQQTYNHLDISVGEALKQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Equus_caballus-PRKAG3(ENSECAP_3236) ---------------------------------------------------------MEP-ELEHALC------------ ------------RTPSWSDLGGPEHQEMSFLEQGDSISWPSPAMTASSERSHGTQGPEALSWTKQKAVEAEELSGPEE-- GPQSR-PAAESTGLEATFPEATPLAQAAPLAGVDTPPPERGILPSDCASSSTGSSTDDLDLGIEFSATAGWGCELG-LVE ETPARYPSPR--------ALLPRLGWDDELQKPGAQVYMHFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEEHKIETWR----EIYLQGCFKPLVSIS PSDSLFEAVYTLIKNRIHRLPVLDPVSGAVLHILTHKRLLKFLHIFG-TLLPQPSFLSRTIQDLGIGTFRDLAVVLETAP LLTALDIFVDRRVSALPVVNEEG-QVVGLYSRFDVIH----LAAQQTYNHLDVSVGEALRQRTVCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Macaca_mulatta-PRKAG3(ENSMMUP_25110) ---------------------------------------------------------MEP-ELEHALH------------ ------------RTPSWSSLGGSEHQEMSFLEQEDSSSWPSPAVTSSSERIHGKWRAKASRWTRQEVVEEGEPPGQGQ-- GPRSR-PAAESTGLEATFPKATPLAQADP-ARVGTPPTGWDCLPSDCIASATGSSTDDVELATEFPATEAWQCELEGLVE ERPAPCPSPQ--------ALFPKLGWDDELQKPGAQTYMRFMQEHTCYDAMATSSKLVIFDTTLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEQHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFG-SLLPRPSFLYRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVVNECG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAQEQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Pongo_pygmaeus-PRKAG3(ENSPPYP_14733) ---------------------------------------------------------MEP-ELEHALR------------ ------------RTPSWSSLGGSEHQEMSFLEQENSSSWPSPAVTSSSERIRGKRRAKASRWTRQKAVEEGEPPGQGE-- GPRST-PAAESTGLEATFPKATPLAQADP-AGVGTPPIEWDCLPSDCTASAAGSSTDDVELATEFPATEAWECELEGLVE EKPAPCLSPQ--------APFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEQHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFG-SLLPRPSFLYRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVVNECG-QVVGLYSRFDVIH----LAAQQTYNHLDVSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Homo_sapiens-PRKAG3(ENSP_436068) ---------------------------------------------------------MEP-GLEHALR------------ ------------RTPSWSSLGGSEHQEMSFLEQENSSSWPSPAVTSSSERIRGKRRAKALRWTRQKSVEEGEPPGQGE-- GPRSR-PAAESTGLEATFPKTTPLAQADP-AGVGTPPTGWDCLPSDCTASAAGSSTDDVELATEFPATEAWECELEGLLE ERPALCLSPQ--------APFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEQHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFG-SLLPRPSFLYRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVVNECG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA---- >Gorilla_gorilla-PRKAG3(ENSGGOP_3197) ---------------------------------------------------------MEP-GLEHALR------------ ------------RTPSWSSLGGSEHQEMSFLEQENSSSWPSPAVTSSSERIRGKRRAKASRWTRQKAVEEGEPPGQGE-- GPRSR-PAAESTRLEATFPKATPLAQADP-AGVGTPPTGWDCLPSDCTASAAGSSTDDVELATEFPATEAWECELEGLVE ERPAPCLSPQ--------APFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRA APLWDSKKQSFV------------GMLTITDFILVLHRYYRS--PLVQIYEIEQHKIETWR----EIYLQGCFKPLVSIS PNDSLFEAVYTLIKNRIHRLPVLEPVSGNVLHILTHKRLLKFLHIFG-SLLPRPSFLYRTIQDLGIGTFRDLAVVLETAP ILTALDIFVDRRVSALPVVNECG-QVVGLYSRFDVIH----LAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGE VIDRIAREQV-HRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA----