>Homo_sapiens-PLEKHA3(ENSP_234453) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP SFSS----------------------------------------------------------- >Pan_troglodytes-PLEKHA3(ENSPTRP_21689) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP SFSS----------------------------------------------------------- >Gorilla_gorilla-PLEKHA3(ENSGGOP_19243) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP SFSS----------------------------------------------------------- >Macaca_mulatta-PLEKHA3(ENSMMUP_2920) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPGQM--MKRSVSHPGS CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCN--------------------DIPLEDPDRPVHCSKNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRLMA--------KKKSESEDTLP SFSS----------------------------------------------------------- >Erinaceus_europaeus-PLEKHA3(ENSEEUP_3777) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------HSADNTRLELIIPGEQHFYMRAVNAAERQRWL-ALGSSKACLTDTR TK-GKEIN-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSP PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLTHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CSSERTSHPMKEPVPTFY------------------------------------------------------RF-----S QRRRRTYSDTDTCN--------------------DIPLEDPDRPVHCSRSTLNGDLAP---------------------- --------------------------------------------------VTIPEESKLTA--------KKTSESEDLLP SFPS----------------------------------------------------------- >Bos_taurus-PLEKHA3(ENSBTAP_1453) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMKQVHTIQ-EFVHH---------------DESHSS LSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLSHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CSTERSSHSIKEPVSALH------------------------------------------------------RL-----S QRRRRTYSDTDSCN--------------------DVPLEDPDRPVHCSRNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRFMA--------KKKSESEDPLL SFSS----------------------------------------------------------- >Mus_musculus-PLEKHA3(ENSMUSP_107551) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHPADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TAKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHR---------------DERHPS PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSASHPGS CSSERSSCSIKEPASALH------------------------------------------------------RL-----P QRRRRTYSDTDSCN--------------------DVPPEDPERPLHCSGNTLNGDLAS---------------------- --------------------------------------------------ATIPEESRLMA--------KTQSE--EPLL PFS------------------------------------------------------------ >Rattus_norvegicus-PLEKHA3_(ENSRNOP_16132) -----------------------------------------------------------------------MEGVLYKWT NYLTS---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TAKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DEDHSS PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSASHPGP CSSERSSCSIKEPASALH------------------------------------------------------RL-----P QRRRRTYSDTDSCN--------------------DVPPEDPERPLHCSGNTLNGDLAS---------------------- --------------------------------------------------AAIREESRLTA--------KTHSESEEPLP PFS------------------------------------------------------------ >Oryctolagus_cuniculus-PLEKHA3(ENSOCUP_4767) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DESRSS PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGS CNSERSSHCTKEPVSTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCN--------------------DIPLEESDRPTHCSRNTLNGDLTS---------------------- --------------------------------------------------ATIPEENRLTA--------KKKPESEALLP PFSS----------------------------------------------------------- >Loxodonta_africana-PLEKHA3(ENSLAFP_5359) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETHSS PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGT CSSERSSHAVKEPASTLH------------------------------------------------------RL-----S QRRRRTYSDTDSCN--------------------DIPLEDPERPVHCSRNTLNGDLAS---------------------- --------------------------------------------------AAIPEENKCTA--------KKKSELEDPLP SFS------------------------------------------------------------ >Monodelphis_domestica-PLEKHA3(ENSMODP_12354) -----------------------------------------------------------------------MEGVLYKWT NYLTG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHPADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLTDTR AKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DDSHSS PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSISHPGS YSSERSSHTVKEPGPSLH------------------------------------------------------RI-----S QRRRRTYSDTD-YN--------------------DIPPEDPDRPVHCSRNILNGDLAS---------------------- --------------------------------------------------ATIPEENRTMS--------KKRSELEDVLP SFSS----------------------------------------------------------- >Ornithorhynchus_anatinus-PLEKHA3_(ENSOANP_13762) -----------------------------------------------------------------------LPSVLFHSS LFIQC---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHPTDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------EENHSS PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSISHPGS YGSERNSHSMKEQISSFH------------------------------------------------------RL-----S QQHRRTYSDTDSYN--------------------DSPFEDPDRPILCSRDALNGDLTS---------------------- --------------------------------------------------ATIPEENRSAT--------KKRTELEDPFL SST------------------------------------------------------------ >Gallus_gallus-PLEKHA3(ENSGALP_32659) -----------------------------------------------------------------------MEGVLYKWT NYLAG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTR TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETCSP PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSISHPGP CYSERDNHSVKEPVSSLH------------------------------------------------------RL-----S QQRRRTYSDTASYS--------------------DTPPEDSQRSAHCPRNAVNGDLVS---------------------- --------------------------------------------------STIPEENRSIS--------NERSELEGSLS SFSS----------------------------------------------------------- >Taeniopygia_guttata-PLEKHA3(ENSTGUP_9483) -----------------------------------------------------------------------MEGVLYKWT -TTSG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTR TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETRSP PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPIQM--MKRSISHPGP CSSERINHSVKEPGLSLH------------------------------------------------------RV-----S QRRRRTVSDTESYS--------------------DTLSEDSQGSAHCSRSAVNGDLVS---------------------- --------------------------------------------------STIPEESKSVS--------KERSELEETP- -FI------------------------------------------------------------ >Anolis_carolinensis-PLEKHA3(ENSACAP_16986) -----------------------------------------------------------------------YNKKLMLCS LFALG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIKAKVHPTDSTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTK TKKEKETN-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EYVHH---------------DKNSSS PTVENMN-----EASSLLSATCDTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSVSHPGT CYPERSGHFTKEPISSSH------------------------------------------------------RL-----S QKCRRAVSDAGPSI--------------------DIPLEDTDRPASCSRDTLNGDLAPP--------------------- --------------------------------------------------AVLPETSLPLCD------SKKEPELEETLP PTF------------------------------------------------------------ >Xenopus_tropicalis-PLEKHA3(ENSXETP_32856) -----------------------------------------------------------------------MEGVLYKWT NYITG---------------------------WQPRWFVLDNGILSYYD------------------------------- ----------SQDDVCKGSKGSIKMAVCEIK--VHSTDNTRMELIIPGEQHFYVKAVNAAERQRWLVALGSSKACLADNR TRKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVNH---------------DEHRPS PSTENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMY-QLVPHD--VSAVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQM--MKRSMSHPGT YISEGGSQSYKD--SSFH------------------------------------------------------RA-----T HRRRSAYSDTETCNN-------------------DVFLEEMEGPAHCLKTGINGDLSP---------------------- --------------------------------------------------ANVQEENRQKS--------KKLCESENSPV SLSF----------------------------------------------------------- >Danio_rerio-PLEKHA3(ENSDARP_73572) -----------------------------------------------------------------------MEGVLYKWT NYMTG---------------------------WQPRWFVLDNGIISYYD------------------------------- ----------SQDDVCKGSKGSIKMSVCEIK--VHPTDNTRLELIIPGEQHFYVKAVNAAERQKWLVALGSSKAGLIDTR TKKERELT-----------------ETTESLKTKMSELRLYCDLLMQQVHTIQ-ESVEQ---------------HEEPAV ANTETRN-----EASSLLSATCETFIKTLEECMKIAN---SKFKTDML-QSSPSDSIMSPVS------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PSPVQMSRMKRSISHPGT YNYERSS--LPKDCVAFQ------------------------------------------------------KS-----S QRRTRTCSDTEAHS--------------------DRGPDDIER-LMFHRANINGDSTP---------------------- ---------------------------------------------------SIPEEVGTST--------KFLSETDTPES DLSL----------------------------------------------------------- >Oryzias_latipes-PLEKHA3(ENSORLP_24324) -----------------------------------------------------------------------MEGILYKWT NYMTG---------------------------WQPRWFVLENGVISYYD------------------------------- ----------SEDDVNKGSKGSIKMSVCDIK--VHPTDSTRLDLIIPGEQHFYVRAVNAAERQRWLVALGSSKAGNLDSK KHGGEKSR-----------------RCPECLKTKMSELRLYCDLLVQQVQTIQSQNNTG---------------DEATPT SEVSTLP-------ASLLSATCTTFIQTLEECMSLAN---QSLMPDLR-PAEKVTLSLN----VK--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------TCLFSSAQMKRSVSHPGT YSFER-G-MLKECVSGAQ------------------------------------------------------RS-----M PRRPRTCSDSSVY------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------- >Gasterosteus_aculeatus-PLEKHA3(ENSGACP_15363) -----------------------------------------------------------------------MEGILYKWT NYMTG---------------------------WQPRWFVLEGGVISYYD------------------------------- ----------SEDDVDKGSKGSIKMSVCDIK--VHPTDTTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLESH RHKDRQLA-----------------QSPDCLKTKMSELRLYCDLLVQQVQTIQSQHTSD---------------TEETPT SESEESE------SSSLLSATCATFIRTLEECMTLAN---QSMTPDLR-PPERVILLLLPMDKTF--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------PAFVSPAQLKRSTSHPGT YSFDRSG-VLKEYSSGGQ------------------------------------------------------KS-----S QRRTRTFSDSSLYDA-------------------ER-----------LLPTLNGDSS----------------------- ----------------------------------------------------IPEER--PDS------PKTTPTDTDTDL SI------------------------------------------------------------- >Takifugu_rubripes-PLEKHA3(ENSTRUP_15479) -----------------------------------------------------------------------MEGILYKWT NYMTG---------------------------WQPRWFVLENGVISYYD------------------------------- ----------SEDDVGKGSKGSIKMSVCDIK--VHPTDPTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLDGH KHKDIEEKT--------------ETTGPDGLKTKMSELRLYCDLLVQQVQTIQTQYTAD---------------TEAPPT VEVAHLLFS--PNKASLLSATCSTFIRTLEECMTLAN---QSLTSDLR-PTERVTTPLL-----S--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------GLL-LFAQMKRSISHPGT YSFDRSG-VLKEYLSAGQ------------------------------------------------------RS-----A QRRNRTCSDSFVYDA-------------------EFHACFMRVCFPGASPGFSGDPAI---------------------- ----------------------------------------------------IPEERGLSVS------PKTTPTDTDTDL SI------------------------------------------------------------- >Tetraodon_nigroviridis-PLEKHA3(ENSTNIP_12769) -----------------------------------------------------------------------MEGILYKWT NYMTG---------------------------WQPRWFVLENGVISYYD------------------------------- ----------SEDDVGKGSKGSIKMSVCDIK--VHPTDPTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLDSH KHKDLCLS-----------------AGPDGLKTKMSELRLYCDLLVQQVQTIQTQYSAD---------------TEAAPT VEVARLP-------ASLLSATCATFIRTLEECMTLAN---QSLTPDLR-PTERVTTPLS-----A--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------AIFSKITQMKRSISHPGT YSFDRSG-VLKEYVSAGQ------------------------------------------------------RS-----V QRRNRTCSDSSVY------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------- >Oryzias_latipes-PLEKHA9(ENSORLP_9275) -----------------------------------------------------------------------MEGTLHKWT NYISG---------------------------WQPRWFVLDGGILSYYD------------------------------- ----------SQEDAWKGCKGSIKISVCEIQ--VHTSDSTRVDLTIPGEQYFYLKAINAAERQKWLVAMGTAKACLTDNR TKREKE-----------------LQENTEALKTKMSELRLYCDLLLQQVNKIK--ES------------------DELGQ TVETGLD------TGKMVKSTCTTFLKTLEECMQIAN---RTFSTDVTAHSPPGTPPLAAIKQNKSIKLANHLNLNLGEK RKD--ASPERSGQSGAEEPEKPEVHPFPS--------------------------------------------------- -----------------------------SKTGFQTAHSPGGSLGK--EPVNPAPGSNQPSPELEHLEQPAEGDEKYDTP EEKETKQEQNNKVDQSQELPNNSEINGVRLQRETASVQEENGE--DETQKVEDTEQVE--TFFSTMSHRFNDIRLDDDNG IPTQEFLDSCYAIVPVLD------------------------------------------------------KLGSTVFA PVKMDFVGNIKKIH------QKLMSDPECFPTLQSIVQHEVRTEVAQVRNSATEALLWLRRGLKFLKEFLSEVNAGERDI QG-----------------------------------------ALNNAYGKTLRIYHGWVVRGVFALALRAAPCYESFTA ALVTREGDELHSEFTNS---MHRDLGMYLPAMEKQLAILDELYEEYNLESDEVV--------- >Takifugu_rubripes-PLEKHA9(ENSTRUP_39875) -----------------------------------------------------------------------MEGMLYKWT NYISG---------------------------WQPRWFVLEGGTLSYYD------------------------------- ----------SQEDAWKGCKGSIKVSVCEIQ--VHSTDATRVDLTIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNR TKREKE-----------------LQENTDALKTKMSELRLYCDLLLQQVNKIK--EN------------------DELVD TAETAID------NGNMVKSTCATFLKTLEECMQIAN---HTFSLDMATQSPPGSPPVAAIKPRK---VSPNIGTDLSEA PVEPVAHDNHSLDSGPEGPEEPDKPDDLH--------------------------------------------------- -----------------------------NKS--TEVTNTKSVTDE--DMVGPNAHAPQDAPESKHYDATTR------EA DDKQTDQEQKHKVDQSLEEETCTDAVQHHQEQEAAPDQHQWETC-TDPAEPEDTEQVE--TFFSTMSHRFSDLRLDDDNG IPTQEFLDSCYAIVPVLD------------------------------------------------------KLGSTVFA PVKMDFVGNIKKIH------QKLMSDPGSFPTLQSIVLNEVQNNVALVRNSATEALLWLRRGLKFLKEFLSEVNAGQQDI QG-----------------------------------------ALNNAYGKTLRQYHGWVVRGVFALALRAAPSYQSFSA ALVLREGDELKSGFTRG---MHRDLGVYLPAMEKQLAILDDLYEEYNLESDEVV--------- >Danio_rerio-PLEKHA9(ENSDARP_59622) -----------------------------------------------------------------------MEGVLYKWT NYISG---------------------------WQPRWFVLEGGTLSYYD------------------------------- ----------SQEDAWKGCKGSIKISVCEIQ--VHPSDFTRVDLIIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNR TKREKE-----------------LQENSEALKTKMSELRLYCDLLLQQVNKIQ--ESPL---------------AETSAG SGEGGDE------TGNLVKSTCTTFLKTLEECMHIAS---RTFNPDLLSRTPPGSPSVATIKPQK-IKSNDPKNLHPGET RKD---LINTSGTSAHES--GPDNEPPPS--------------------------------------------------- -----------------------------PQENISTAHTESGLMEDQNDLIEPNNGS---SSSTQDHEEPVE------EQ QKDGSTEDADHSQEEQQEVSMSPTQNKQEVQEDIQTDLELNETQSENKQEEEDEDKVD--TFFSTMSHRFSDIILEEDSG IPTQAFLDSCYAIVPVLD------------------------------------------------------KLGPTVFA PVKIDFVGNIKKIQ------QKVVSDPESFPTLQSIVLHEVKTEVAQVRNSATEALLWLKRGLKFLKEFLYEINTGVKDV QG-----------------------------------------ALYNAYGKTLRQYHGWVVRGVFALALRAAPSYEGFMA ALVSYEGDELKEGFRTG---MHRDLDIYLPAMENQLSILDTLYEEYGLESDEIV--------- >Anolis_carolinensis-PLEKHA9(ENSACAP_936) -----------------------------------------------------------------------QAYVIQLCS FFFPG---------------------------WQPRWFLLAGGVLSYYD------------------------------- ----------SREDAWKGCKGSIQMAVCEIQ--VHPTDNTRVDLIIPGEQYFYLKSKNAADRQKWLVALGTAKACLTDIR TLKEK-----------------EFSENTDALKTKMAELRLYCDLLVQQADKTK--VTP----------------LSNVSE VLQNGVD------TGALLTTTCTTFLKTLDECMQIAN---VAFSSELLYQPTSGSPHSAFYKLNK-LKLPSIFSRGVAER QMELKNTENGYIYANAN-LPEQTPVLLKT--------------------------------------------------- -----------------------------DDSLYSSKINVIVAIIE--------------------------------KN NTCNNTNNNRD--GSKKDGKDKLLPKIPDRDTKSLELPADSIGKSTPLSEETNKDFK---TFFSAMSIRFSDIELSEDEG IPTEEFLRSCYEIVPVLD------------------------------------------------------KLGPTVFA PVKMDFEGNIKKIN------QKYITSKDDFHTLQKLILHEVSSGDAQLRNSATEALMWLKRGLKFLKEFLIEIKNGEKNI QT-----------------------------------------ALNHAYGKTLRQYHGWVVRGVFALALRASPTYEGFAL ALSIGEHKYQEDIFYNS---MQRDLDIYLPAMEKQLSILDALYEEHGLESNEVV--------- >Ornithorhynchus_anatinus-PLEKHA9(ENSOANP_17160) -------------------------------------------------------------------------------- ---SG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNVAERQRWLVALGSAKACLTDSR AQKEK-----------------EFTENTETLKTKMSELRLYCDLLVQQVDKTR--EAT----------------AAGVSG S-EEGID------VGALLRSTCNTFLKTLEECMQIAN---TTFTSELLYPTPPGSPRLAVLKPSK-MKHPIIPIHNPVER QMELNSCENGSLNVEVTDSEPTPVTN-ET--------------------------------------------------- -----------------------------PSDLKLAENDGTMSAEE--------------------------------SS GDGIAFSGQE----TKQAGERGISPASGRCDNDLMPPGGDFLSESTKSQREEEKEEVR--TFFSAMNTSFSDIELLEDSG IPTEAFLESCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKERDHESCVERIIKNQSVKSQKRRVIVIGAVLKGAYTAKFVGHAEGWADRGNKGLSMERISLKFSNSSL QT-----------------------------------------VKDNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTVREGDDQKEAFSIG---MERDLNVYLPAMEKQLEILDTL--------------------- >Gallus_gallus-PLEKHA9(ENSGALP_18216) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SQEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSR TQKEK-----------------EFTENTEALKTKMSELRLYCNLLVQQVHKTK--EAS----------------ISAVSE P-ESGID------VGALLKSTCDTFLKTLEECMQIAN---TAFTSELLHQTPPGSPHLAVLRTNK-IKHSVLSSHTSTER QMELNPCENGSIKAENN-QQEQT--LIKS--------------------------------------------------- -----------------------------LACLN-------LETNE--------------------------------RS SDVSVEDHIEE--VMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEG IPTEEFLESCYAIVPVLD------------------------------------------------------KLGPTVFA PVKMDFVGNIKKIN------QKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVA ALSVEDCDPQEETFYRA---MQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV--------- >Taeniopygia_guttata-PLEKHA9(ENSTGUP_3106) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SQEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSR TQKEKGKNTLLL--------AHNFTENTEALKTKMSELRLYCNLLVQQVHKTK--EAS----------------ISGVSE P-ESEID------MGALLKSTCDTFLKTLEECMQIAN---TAFTSELLHQTPPGSPNLAVLRMSK-VKHSVLPSHTSTER QVELNPCENGCVKGEIK-HQEQA--VIKS--------------------------------------------------- -----------------------------LECLN-------LETNE--------------------------------GA GDIYVEDHVAK--DLANDGEDKLQAVEGCGAHKLLQSETNSLSGLTLCEEERNENDS--PTFFSVMSNRFSDIELQEEEG IPTEEFLESCYAIVPVLD------------------------------------------------------KLGPTVFA PVKMDFVGNIKKIN------QKFITNKEEFDTLQKIVLHEVNAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVA ALSVDECNPQEETFYKG---MQRDLNIYLPAMEKQLNILDTLYEVHGLESDEVV--------- >Monodelphis_domestica-PLEKHA9(ENSMODP_19111) --------------------------------------------------------------------------HHGCLS FLFAG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSADNTRMDLIIPGEQYFYLKARNVAERQRWLVALGSAKACLTDIR AQKEKG----------------EFTENTETLKTKMSELRLYCDLLVQQVNRTK--EAA----------------AAGAAD P-KEGID------VGTLLKSTCNTFLKTLEECMQIAN---TAFTSELLYRTPPGSPRLAALKPSK-TKLPIMPIHNALER QIALNSCENGSLNTEGSDSEEALMRN-ES--------------------------------------------------- -----------------------------PSRGRPEMGRSVAAADD--------------------------------GD DPLAALDDFRPPPPSNLMGLEATLSSTGPLSFSICKPKG------RRAGAAQQEEEVQ--TFFSAMNTSFSDIELLEDSG IPTEAFLESCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNKAEFTTLQKIVLHEVGADVAQVRNSATEALLWLKRGLKFLKGFLTEVRNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTIREGDHHKEAFSLG---MQRDLNLYLPAMEKQLDILDNL--------------------- >Pteropus_vampyrus-PLEKHA9(ENSPVAP_12191) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVGKTK--EVT----------------ATGVSS S-EEGVD------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIVPIHNSLER QMELNNCENGSLNMEINDDEEIVMKN-KS--------------------------------------------------- -----------------------------SLYMKSAEIDCSISSEE--------------------------------NT DDNITVQGEI----MKEDGEENLGNHD----TNVLQPGSDSSSSSPESQWEEGQEVIP--TFFSTMNTSFSDIELLEDGG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNREEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTVKEGDHQKAAFSVG---MQRDLSLYLPAMEKQLAILDTL--------------------- >Macaca_mulatta-PLEKHA9(ENSMMUP_16456) ---------------------------------------------AAGAPRLLGSGAVRGPAGVGRVAAGAMEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKGK---------------FFAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER QMELSTCENGSLNMEINGEEEILMKN-KN--------------------------------------------------- -----------------------------SLSLKSAGIDCSISSEE--------------------------------NT DDNITVQGEI----MKEDGIENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVDG--------SC------WKY--------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------------- >Mus_musculus-PLEKHA9(ENSMUSP_112466) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVA----------------TAGVTD S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAVLKSSK-MKHPIIPIHNSLER SMELNSCENGSLSIEVNGDEEILMKT-KS--------------------------------------------------- -----------------------------SLYLKSTEVDCSISSEE--------------------------------NT DDNVTVQGEI----MKEDGEENLESHD----KDPAQPGSDSV-CSPESPWEDNEEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTIKEGDHQKEAFSAG---MQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV--------- >Rattus_norvegicus-PLEKHA9(ENSRNOP_13528) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVA----------------TAGVAD S-EEGID------VGTLLRSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAVLKSSK-MKHPIIPIHNSLER PIELNSCENGSLSVEVNGDEELLMKTKKS--------------------------------------------------- -----------------------------SLYLKSTKADCNISSEE--------------------------------NT DGNTTVQGER----MKEDGEENLESHD----RDLAQPGSDSV-CSPESPWEDSEEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVARVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTIKEGDHQKEAFSAG---MQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV--------- >Homo_sapiens-PLEKHA9(ENSP_336073) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------MSELRLCCDLLVQQVDKTK--EVT----------------TTGVSN S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAMLKSSK-MKHPIIPIHNSLER QTELSTCENGSLNMEINGEEEILMKN-KN--------------------------------------------------- -----------------------------SLYLKSAEIDCSISSEE--------------------------------NT DDNITVQGEI----MKEDRMENLKNHD----NNLSQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCCAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVENIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRATPSYEDFVA ALTVKEGDHRKEAFSIG---MQRDLSLYLPAMKKQMAILDAL--------------------- >Homo_sapiens-PLEKHA8(ENSP_407802) ---------------------------------------------AAGAPRLLGPGAVRGPAGVGRVAAGAMEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER QMELSTCENGSLNMEINGEEEILMKN-KN--------------------------------------------------- -----------------------------SLYLKSAEIDCSISSEE--------------------------------NT DDNITVQGEI----RKEDGMENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTVKEGDHQKEAFSIG---MQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV--------- >Macaca_mulatta-PLEKHA8(ENSMMUP_16458) -----------------------------------------------------------------------MEGVLYKWT NYLSG---------------------------WQPRWFLLCGGILSYYD------------------------------- ----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER QMELSTCENGSLNMEINGEEEILMKN-KN--------------------------------------------------- -----------------------------SLSLKSAGIDCSISSEE--------------------------------NT DDNITVQGEI----MKEDGIENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA ALTIKEGDHQKEAFSIG---MQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV--------- >Anopheles_gambiae-PLEKHA8(XP_565108) ---------------------------------------------MADDYYVQNNSNSDDSEVELNLSSPELKGYLSKWT NYIHG---------------------------WQPRFIVLKDGTLSYYK------------------------------- ----------SEQDSDFGCRGAISLQKATIK--SHEFDECRFDVAIG-QNVWYLRAETPEDKSNWIEVLQSYKTDQPETV SLRRHGSTISLQSNTLSTASGSSLKRVSRGLREKLHEIETFRDILYGQIDTLQRYFDALHTK-----------NEDQPPL DLGDGLKPIDFRGEAITFRETTAGVIITLQHCLDIISQKEESFKKKLDKEQERRRKAEELYRTAKDELAKNRNSVIPGPD LEEGPHSTIPEDEFFDAVETGLDKIEEDR--------------------------------------------------- ----------------------------------QLRVRLKYQSQQ---------------------------------V SCMQTEALAETEDEIPQLAEDFGTGAQAKSHKLWPEIDRICTEQLTQARQGVGEDGNGWQLFADEGEMKMYRREEEVDGM VIDPLKSCHVVKGVTAREMCH---------------------------------------------------YFFDPAYR NDWETTLEDVQIVDN-----VAPDTLVFLQTYKRIWPASQRDALFWSHMRRITDNLDAGANDVWIVCNHSNQNEEYPPAN QG----------------------------------------------KCVRIYLTVILVCQTYLPPGKDSKTATRDDLT CKITYCSTVNPGGWAPATVLRAIYKKEYPKFLKRFTGYVVDQCKAKPIMY------------- >Caenorhabditis_elegans-PLEKHA3(Y47D3A.17c) MVPNHCVMLDDMQKAAASGISGKNEKKRRAKIDSNEENDDISKRRQNGGNGEIRRDEEKAEKSGDKDPPRQFPSLLTSCS SFYSSSPSTSTYCSLSSLSPSSLPPPLQKSTKIHRRIMGTLRGRLRQARKQITWCAFPVRARRKAHHRDDESVYESACGD SEKLFGLQERNPSEVGHTCRGSINLQEARVH----TDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRA ESEEDEDAQMAKT---DSNRSDALILANRQMSGKLCDLRTAANMMNKQGDELMRALN---------------GTVETDKN SLAERADLL--KMTTSAVLQAAEEFVELSEQSAKRLN---KIVAVEQKEKALLQEQLEALAKQHSSLERAA--------- --SKCARGAAPVSVYSDQEDDEFHDAEED---------------LAMPCSNSNGPPATAGVHLTPTKRHIG--------- --------------------------AGDPSSSTCSDSGAVVVVGAHKGGRQRRTTVPERPNLPINLWSIMKNCIGKELS KIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLG WRSVTEQVSHHPPAAAHH-----AEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVG KLWIDNHGDMEITN------HETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNH EK-PKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQR VVRRRREAEKELAMKKGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF >Ciona_savignyi-PLEKHA3(ENSCSAVP_16452) --------------------------------------------------------------------SDHFKGWLWKWT NYIKG---------------------------YQRRWFVLSNGLLSYYR------------------------------- ----------SQAEMAHTCRGTINLAGSFIV----TEDSCNFMISNGGTQTFHLKASSEVERQRWITALELAKAKATRFT ESDDSSDE--------DSLVKNDLRNTLRALVGKLDDLATCNDLISKHGGALQRALSDLESIENNLISQNDSPALSSRIK TVNERATLF--RITSTAMINACSDFLQLAQNQGKRWH---KAIIHEREQRLRLEETVETLAKQHNTLERALHAGTGPPRP DPSNKDDESKQTNEIASDDEDEFVDASDK----------------GFTTEFVKDHRKTPSTASSSSIDANN--------- ------------------------------ASVVLNTANVSDKSDPDKIIRERRSRIPDKPNYSVNLWSIMKNCIGKDLS KIPMPVNFNEPLSMLQRLGEDLEYSDILDRAEKCATSQEQMAH------------------PFNPLLGETFELDRRSDLG FKMICEQVSHHPPAAMHVDSANVSENSGWSYWEEITLVSKFRGKYLNVAPTGVVHLKFHKSGNYYTWRKVTTTVHNIIVG KLWVDQSGDAEVVN------HTTGDRCKHKYFAYSYFSRETPRKVSGVVQDAKGIAHYVMSGTWDSYMECAKIVTTNNAN KSKPLYKTLPS--KRLWQVHPLPVGADKMYFLTKLAVTLNEMETGIAPTDSRFRPDQRVMEEGNWDLANDLKQRLEDAQR SRRKRRE----AAIAMGQEVEPYKPVWFEPQKCQFSGEVTHVYKNSYWESKKAQNWSACPTIF >Drosophila_melanogaster-PLEKHA3(FBpp_84176) -------------------------------------------------------MTDAAGNALAEKGLPEMKGWLLKWT NYIKG---------------------------YQRRWFVLSKGVLSYYR------------------------------- ----------NQSEINHTCRGTISLHGALIH----TVDSCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAI ECEEEEETETA-----HVVPSQEISSVVRDLTDRLESMRTCYDLITKHGAALQRALNDLETNEE--------ESLGSRTK IVNERATLF--RITSNAMINAGNDYLHTAEAQGHKWS---KMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVR--QNK PVSSTSGAGTAGSLVTSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQVEGHLEGSSSESDEQKRT VQTVQQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNCIGKDLS KIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYG WRCLAEQVSHHPPVAALH-----CESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVG KLWVDQHGEMEIRGSQ----AAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSV SS-PTYTTGEF--KLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQR TERRRRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY >Anopheles_gambiae-PLEKHA3(XP_309799) --------------------------------------------------------SSTSVAAAASQPEPDMKGWLLKWT NYLKG---------------------------YQKRWFVLSKGVLSYYR------------------------------- ----------NQAEMAHTCRGTISLHGALIH----TVDSCTFVISNGGTQTFHIKAANEVERQSWVTALELAKAKAIRAM ESDEEEEDNTA-----NTIPSEELNLVVRELTVRLENLKTCYDLITKHGAALQRALSELETG----------DDLANKTK IVSERATLF--RISSNAMINACSDYLQTAQTQGHKWS---KMLQHERDQKLHLEEMVEQLARQHSHLEQAATRHR--PSD HVSSATKSFNAATSASDDEDNEFYDAQEE---GGSVTQEDSSFILNIPVTTHHNHRRNSNDATGSSSEGEDGNSETQQCR SLTAGHLSLSFSPRTGISAENLDNMDVTDRISVHSSQALTPTLANQSKVVRKRRTRVPDKPNYPLNLWSIIKNCIGKDLS KIPMPVNFNEPLSMLQRLTEDFEYSEILDKAAQAKDTCEQLAYVTAFTVSSYSTTSNRTGKPFNPLLGETYECDRTDDLG WRCINEQVSHHPPMAAQY-----CEGRGWRCWQEFTMTSKFRGKYIQIVPLGYAHVEFPATGNRYTWRKVTTTVHNIIVG KLWVDNHGDMEIFGER----NAKGVKCHLKYLPYSYFTRDTQRRVKGVVMDSSNQVKWVVNGTWDSKIEIAPVTSTSGST EN-PVYKTGNY--KTAWTRRMPPPDSDRYYNFTLLACQLNEPEPGVAPTDSRLRPDQRLMEDGKWNESNQEKLRLEEGQR ARRRQREAEAETAAAEGRPYPPYEPIWFGKEKEEGTDNLVHVYNGTYWDAKAKGDWSKCSTIF