>Homo_sapiens-ING5(ENSP_322142) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDILAAEYI---STVK---TLSPDQRVERLQKIQNAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD---------------------------------- -------------------------------------------------------------FESSGGRGLK--KGRG--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKHKG G---------------------------------SEFTD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKRKKK---------------------- >Macaca_mulatta-ING5(ENSMMUP_22341) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDILAAEYI---STVK---TLSPDQRVERLQKIQNAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD---------------------------------- -------------------------------------------------------------FESSGGRGLKS-NGRG--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKHKG G---------------------------------SEFTD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKRKKK---------------------- >Canis_familiaris-ING5(ENSCAFP_19298) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDILAAEYI---STVK---TLSPDQRVEHLQKIQSAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD---------------------------------- -------------------------------------------------------------FESSGGRGLK--KGRA--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKHKG G---------------------------------SEFTD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QERRKKK---------------------- >Equus_caballus-ING5(ENSECAP_12148) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------IENLP-CELQRNFQLMRELDQRT--EDKKAEIDILAAEYI---STVK---TLSPDQRVEHLQKIQSAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD---------------------------------- -------------------------------------------------------------FESSGGRGLK----RG--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKHKG G---------------------------------SEFTD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QERRKKK---------------------- >Mus_musculus-ING5(ENSMUSP_27505) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDILAAEYI---STVK---TLSSAQRVEHLQKIQSAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDR-MDGSD---------------------------------- -------------------------------------------------------------FESTGARSLK--KGRS--- QKEKRSSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKHKS G---------------------------------SEFTD---SILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKRKKK---------------------- >Monodelphis_domestica-ING5(ENSMODP_10749) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDSLAAEYI---STVK---TLSPEQRVEHLQKIQTAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKEK-MEGSD---------------------------------- -------------------------------------------------------------LESSGGRGLK--KGRG--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKLKG GWTRTRPRW-------------------------SEFAE---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKRKK----------------------- >Ornithorhynchus_anatinus-ING5(ENSOANP_20022) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------LCQ CDHTDTYLGGIENLP-CELQRNFQLMRELDQRT--EDKKAEIDLLAAEYI---STVK---NLSPEQRVEHLQKIQNAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MDGSD---------------------------------- -------------------------------------------------------------FESPGGRGLK--KGRG--- QKEKRGSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKLKG G---------------------------------SEFAD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKRKKK---------------------- >Gallus_gallus-ING5(ENSGALP_10199) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-CELQRNFQLMRELDQRT--EDKKAEIDRLAAEYI---ESVK---SMSAEQRVEHLRRIQSAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-LEGSD---------------------------------- -------------------------------------------------------------FESSGSRNLK--KGKS--- QKDKRSSR----GRGK-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKLKG G---------------------------------SEFAD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QEKKKSKK--------------------- >Taeniopygia_guttata-ING5(ENSTGUP_6097) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------FIVGIENLP-CELQRNFQLMRELDQRT--EDKKAEIDSLAAAYI---ESVK---NMLPEERVEHLRKIQSAYSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-LEGSD---------------------------------- -------------------------------------------------------------FETPGSRSLK--KGRS--- QKDKRSSR----GRGR-RTSEED--------------------------------------------------------- ---------------------------------------------------------------------TPKK--KKLKG G---------------------------------SEFAD---TILSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCV-QERKKKK---------------------- >Danio_rerio-ING5(ENSDARP_40700) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AIYLEHYLDSIENLP-CELQRNFTLMRELDNRA--EEKKCEIDKLAEEYI---ANVR---NLAPDQRVEHLQKIQNGFSK CKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFENELKEK-LDVSG---------------------------------- -------------------------------------------------------------YESPDNRTHKKVTGRGN-- LKEKRRPK----GRGR-KSSDDE--------------------------------------------------------- ---------------------------------------------------------------------SPRK--KKMKN S---------------------------------PEFPE---SILPVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCT-QDRKKK----------------------- >Oryzias_latipes-ING5(ENSORLP_1915) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AIYLEHYLDSIENLP-CELQRNFTLMRDLDSRT--EEKKGEIDRLAEEYI---SNVK---NLASEQRVEHLQKIQNAYSK CKEFSDDKVQLAMQTYEMVDKHIRRLDADLARFENELKEK-LELTG---------------------------------- -------------------------------------------------------------YDSTDSRTLKKGDSRG--- QRDKRGSR----GRGK-KGSDDD--------------------------------------------------------- ---------------------------------------------------------------------SPKK--KKMKI S---------------------------------QDLSD---ALLPMQ---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLATKPKGKWFCPRCT-QDRKKNKR--------------------- >Takifugu_rubripes-ING5(ENSTRUP_41448) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AIYLEHYLDSIENLP-CELQRNFTLMRDLDNRT--EEKKAEIEKLAEEYV---VTVK---NLASEQRVEHLQKIQNAYSK CKEFSDDKVQLAMQTYEMVDKHIRRLDADLARFENELKEK-LEVGG---------------------------------- -------------------------------------------------------------YESTDGRAVKKGESRG--- LREKRGSK----GRGR-KGSDED--------------------------------------------------------- ---------------------------------------------------------------------SPKK--KKMKN S---------------------------------PDLSD---ALLPMQ---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVDLATKPKGKWFCPRCT-QDKKKNKH--------------------- >Gasterosteus_aculeatus-ING5(ENSGACP_14629) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AIYLEHYLDSIENLP-CELQRNFTLMRDLDNRT--EEKKGEIDQLAEEYV---VKVK---NFASEQRVEHLQKIQNAYSK CKEFSDDKVQLAMQTYEMVDKHIRRLDADLARFENELKEK-LELSG---------------------------------- -------------------------------------------------------------YESTEGRSVKKPETRG--- LRDKRASR----GRAK-KASDED--------------------------------------------------------- ---------------------------------------------------------------------SPKK--KKIKN S---------------------------------PELSD---ALLPMQ---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCTIEWFHFACVDLASKPKGKWFCPRCT-QDKKKK----------------------- >Oryzias_latipes-ING4(ENSORLP_15230) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFNLMRDLDQRT--EDLKGQIDSLAKEYT---ANAR---TLSSEQKLSILRQIQQSYSK CKEFGDDK----------VDKHIRRLDTDLARFEADLKEKQIESTD---------------------------------- -------------------------------------------------------------YDSTSSKGKKG-DTR---- QKEKKVAK----TRSKVKSSDEDG-------------------------------------------------------- ---------------------------------------------------------------------SPKSAQKKVKL LQP-------------------------------GEFNSPSSNFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNTECSIEWFHFACVGLTTKPRGKWYCPRCS-QDRKRK----------------------- >Gasterosteus_aculeatus-ING4(ENSGACP_13616) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -MYLEHYLDSIENLP-FELQRNFNLMRDLDQRT--EDLKGQIDSLAKEYT---ANAR---TLSSEQKLSILRQIQQSYSK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESTD---------------------------------- -------------------------------------------------------------YDSTSSKGKKV-ETR---- QKEKKTAK----TRSKVKSSDEDG-------------------------------------------------------- ---------------------------------------------------------------------SPKSAQKKVKL LQP-------------------------------GEFNSPTNNFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCS-QDRKRK----------------------- >Takifugu_rubripes-ING4(ENSTRUP_5742) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFNLMRDLDQRT--EDLKGQIDSLAKEYT---ANAR---TISSEQKLSILRQIQQSYSK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESTD---------------------------------- -------------------------------------------------------------YDSTSSKGKKG-DTR---- QKEKKMAK----TRSKVKSSDEDG-------------------------------------------------------- ---------------------------------------------------------------------SPKSAQKKVKL LQSNR-----------------------------GEFNSPSNNFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCS-QDRKRK----------------------- >Danio_rerio-ING4(ENSDARP_45244) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKGQIDSLAREYT---ANAR---TLSSEQKLSLLRQIQQSYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESTD---------------------------------- -------------------------------------------------------------YDSTSSKGNKS-DIRG--- PKKKEVNR----ARSKVKNSDDDC-------------------------------------------------------- ---------------------------------------------------------------------SSKSGQKKVKL TQS-------------------------------TEFSTPAVNFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNTDCSIEWFHFACVGLTTKPRGKWYCPRCS-QERKKK----------------------- >Gallus_gallus-ING4(ENSGALP_23298) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKSEIDKLATEYI---SNAR---TLSSEEKLGLLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRA--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKTAQKKLKL VRTS------------------------------TEYGMPSVTFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Taeniopygia_guttata-ING4(ENSTGUP_13715) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKSEIDKLATEYI---SNAR---TLSSEEKLGLLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRA--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKTAQKKLKL VRTS------------------------------TEYGMPSVTFGNVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Equus_caballus-ING4(ENSECAP_22343) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---NLSSEEKLALLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRT--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKAAQKKLKL VRTS------------------------------PEYGMPSVTFGSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Homo_sapiens-ING4(ENSP_380024) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---SLSSEEKLALLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRT--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKTAQKKLKL VRTS------------------------------PEYGMPSVTFGSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Macaca_mulatta-ING4(ENSMMUP_22340) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---SLSSEEKLALLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRT--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKTAQKKLKL VRTS------------------------------PEYGMPSVTFGSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Mus_musculus-ING4(ENSMUSP_121519) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---SLSSEEKLALLRQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRT--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKAAQKKLKL VRTS------------------------------PEYGMPSVTFGSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Canis_familiaris-ING4(ENSCAFP_21782) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---SLSSEEKLALLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRT--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKATQKKLKL VRTS------------------------------PEYGMPSVTFGSVHRICGGHFF------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------SFLCSIRAPDFRF FHLPPF---------QCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Monodelphis_domestica-ING4(ENSMODP_22570) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAA GMYLEHYLDSIENLP-FELQRNFQLMRDLDQRT--EDLKAEIDKLATEYM---SSAR---SLNSEEKLALLKQIQEAYGK CKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD---------------------------------- -------------------------------------------------------------YDSSSSKGKK--KGRV--- QKEKKAAR----ARSKGKNSDEE--------------------------------------------------------- ---------------------------------------------------------------------APKAAQKKLKF VRTS------------------------------PEYGMPSVTFGSVH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS-QERKKK----------------------- >Ciona_savignyi-ING1(ENSCSAVP_651) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEQYLDSLETLP-FELQRNFQLMRQLDQRS--EDLKVEIDDKTESYV---GDAK---ALSPQQRVKKIKEIQERYYK CRGFADDKVQLAMQTYEMVDKHIRRLDSDLARFEADLKEKSVQDTTGSSKVRNIDAMYCGAFALMYTHK----------- ------------------------------------------------------------YWGNPHHRHLHIIIQGDCDA IMSERKRK----KKGR-IASEDE--------------------------------------------------------- ----------------------------------------------------------------------GKSGRKKLKT GEFR--------------------------------WCIELAPLVSAYQ--SSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNQDCPIEWFHFGCVGLTTKPKGKWFCPKCKDRDRKKK----------------------- >Ciona_intestinalis-ING1(ENSCINP_20230) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEQYLDSLENLP-FELQRNFQLMRQLDQRS--EDIKVEIDGRTEGYV---REAK---SLSPPQRVKKIKEIQERYLK CREFADDKVQLAMQTYEMVDKHIRRLDSDLARFEADLKEKSIQDATGTSKVGSLCS------------------------ -------------------------------------------------------------WESLGANGVYRVIVMSLSE TRSERKKV----ARHRKMRARTD--------------------------------------------------------- ----------------------------------------------------------------------GKN-KRRVSV IEM------------------------------------MTSPLAAAYQ--SSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNQDCPIEWFHFGCVGLQTKPKGKWFCPKCKDRDRKKK----------------------- >Branchiostoma_floridae-ING4(XP_002588507) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-FELQRNFSLMRDLDQRS--QDLRGEIEKMAEDYV---SDVK---GLSPEKRVERLKNIQSAFNK SKEFGDDKVQLAMQTYEMVDKHIRKLDADLARFEAELKNKTVDSPT---------------------------------- ------------------------------------------------------------VDPGPSGKSNK--RGKK--- -QDKTTSKKG--SQKKGRLSDDETPKL----------------------------------------------------- ------------------------------------------------------------------NKKKQKTSHTKVEA A---------------------------------QPVILPSLPVAFTH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFGCVGLTTKPKGKWFCPKCT-MERKKK----------------------- >Branchiostoma_floridae-ING5(XP_002585609) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT AMYLEHYLDSIENLP-FELQRNFSLMRDLDQRS--QDLRGEIEKMAEDYV---SDVK---GLSPEKRVERLKNIQSAFNK SKEFGDDKVQLAMQTYEMVDKHIRKLDADLARFEAELKNKTVDSPT---------------------------------- ------------------------------------------------------------VDPGPSGKSNK--LQEV--- -KSKT--------------------------------------------------------------------------- -----------------------------------------------------------------------RPPARRVHR R---------------------------------KPVILPSLPVAFTH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFGCVGLTTKPKGKWFCPKCT-MERKKK----------------------- >Strongylocentrotus_purpuratus-ING4(XP_001201481) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MAT ALYLEQYLDSIENLP-FELQRNFTLMRDLDQRT--QELAKSIDEDTVNYL---KTVK---DLKPEQRAERLKKINHSFTK SREYGDDKVQLAMQTYEMVDKHIRRLDADLARFEQELKERTLEQAS---------------------------------- ---------------------------------------------------------------PVEGREKK---KKG--- -AEKSAKK----LKKAGRSSDDE--------------------------------------------------------- ---------------------------------------------------------------------TPKTSRKKMKT S------------------------------------ARFVVIVYCSH---PSDVL------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVGLVTKPKGKW------------------------------------ >Drosophila_melanogaster-ING1(FBpp0080103) -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MSS AIYLENYLDGLESLP-TELERNFKLMRKLDDRA--QTAMKSIDSHAKDFM---RKLGENGAMSEDERRERQEDIKALFGK AKEYSDDKVQLAIQTYELVDKQIRRLDNDLARFEGEIQEKASSTRAKS-------------------------------- -------------------------------------------------------------EEVVAKKGRKKTKDSKTTG KKKKSASSDEETGRGNNQSNANSSVNS----------------------------------------------------- ------------------------------------------------------------------SSNAGQGSKKKKSK VNQEKETRKGGAQKKTVEV---------------DDSEKESCHTAATH---PSDVM------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DMPVDPNEPTYCL CHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKCT-QDRKKK----------------------- >Drosophila_melanogaster-ING3(FBpp0074385) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEHLP-QELRDRFTEMRELDLAV--QNNMDSLDKKAHMFFKQCKRDE----LQHESMDTEFHSLRGEYFK VMEDADEKVAIATQIHELVERYLRRLDSELFKFKCELEADNNGITEILERRSLELDGNSTAATALLLSMNQKENRYYGAS SANTMVNSSTGHATGAATGSSGIALVSGAAGTGGALSSISTAQLGSSQRHRKLEKRRETICTVPVQEKRANLNHSLPVVG SGSTTAAAASSSSATTAAAAASLASATTAQTHVSNHIGSIAATHLTLPVAMGVAGGSSSLASSSLATGTGSLVRQLPTNL THTVLSTSGGATAAAAAGGNSTSVVAAGTAHGHAHVSGHSAAGATVTYNLQQLGGG-AAASSAIAAAASQAIVATQQMQQ GRRTASLKASYEAIHGTAGTTTDFWTQAGQGGLQQSTAGSVTVAAGTALATGAAGGSSTGSHHSHHSQSHHGGHGHGHGH GHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALTLPTVQPTAGSSSGNSIGSSSSISLESVNKLTTSAALAAASAT TTYMSVGGQALLAMTPGGGGGGNLAESSAEGVPAGMIAMNLPTTTVTPGSSLTIGENGLVVEQTNEGEWSYDPNEPRYCT CNQVSYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPKCTASMRRRGNRKN------------------- >Ciona_savignyi-ING3(ENSCSAVP_824) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYIELIEHLP-SDLRERFTDMREMDLQV--QNTVDSLDDRVKKLFQKCFLKK----SKITGADQNYEEIRNEYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELSKFKMELEADNAGITEVLEQRSLELDNPSSQLRSNK-----------VFI QLLKERRKHSTAVGGIP--------------------------------QTSTA--VGHINGEGPPEKKIKSEQIIKSEL LAQLQDTS--DYQSKSMIEVIDTGGR---------------------------MQSG-PLHLQEGKR------------- -------------------------------------------ICIELKLCDPG-------TKEN--PAMSGRRPSFIKL ES---TNRTDYDKIIVD-------SYDIGDQVSDSSVCSITGGAVHRPLRTKKQTSKAAAWVQQRQQAEAR--------- ---------------------LEQRKK-------------------------------DHVPTTSADGESTVEVVGESS- -----------------------------------------------------------------AVEWNYDPNEPRYCL CNQVSYGEMVGCDNDKCPIEWFHYGCVGLNQAPTGKWYCPQCTQTMKRRNKNK-------------------- >Ciona_intestinalis-ING3(ENSCINP_28225) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYIELIEHLP-SDLRERFTDMREMDLQV--QNSVDSLDDKVKKLFQKCFMKK----TKITGADQVYEEIRNEYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELSKFKMELEADNAGITEVLEQRSLELDNPQSQQRTSVSFRLSISKLHFILS QLQKERRKH--AVGGTP--------------------------------HTSTSNTVTINNGDGPPEKKIKSEQILKSEL LAHLQDNSNLEYTTKVLNEVAEIGGR---------------------------EVAGFPIHYHEG--------------- -------------------------------------------WCGLFTAEIPGGS-LENEMKENQSSAQPTRRTSLVKH EIKIESRTSEYDRISVD-------SLDANEQVSDSSICSATGGAVHRPFRAKKQTSKAAAWVQQRQQAEAR--------- ---------------------LEQRKK-------------------------------ETATVTDSN-DPGVEVIGESS- -----------------------------------------------------------------NVEWNFDPNEPRYCL CNQVSYGEMVGCDNDKCPIEWFHYGCVGLEQAPTGKWFCPQCTQTMKRRNKNK-------------------- >Strongylocentrotus_purpuratus-ING3(XP_001191966) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-IELKERFTEMREMDLQI--ENSVDTIEEKVKKFFEAAKKL------KTESKQQQYDTLRKEYYK LLDSADEKVQIANQVYDTVERYLRKLDQEVSRFKMELEADHAGITEVLERRSLELDS-SQPMK----------------- --SGSAKSD----------------------------------------KRKVS-------HDNHVDKRVNADKILSTLA TNAVQDIAP-SRSSSLSSNSNSLVNSR------------------------ESSGNSQPSLP------------------ -----------------------------------------------YSLDNVGSS-----SAIAMAAAQAVSNTLHMQQ GRRTASLKASYEAIK--------------------SGGYSGLGTLGRDFTYGNTST--SDGVPSSSS-SSTK-------- --------------------SSRHRNK----------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------- >Danio_rerio-ING3(ENSDARP_31200) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVNEFFTNAKKN------KPEWREEQMEIIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLEMDSPSQPVN----------------- --NHHVHSHTTVE------------------------------------KRKYSTPAHH-TTEHVPEKKFKSEALLSTLT SDATKENTPGCRANST-SSSNSMYN----------------------------VNSSQSLTSS----------------- -----------------------------------------------YNLSPLPAGPAAGAGAISMAAAQAVQATAQMKE GRRTSSLKASYEAVKN-----NDF-LGRDFTMSRDSSSYSSS-ALASTLTQPLTSTNSSDSRTARKTKSNTK-------- --------------------SSNHQSS-----------------SSSSSSS---LSSCSSSSALAHELVQTT--VTETDT S---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Takifugu_rubripes-ING3(ENSTRUP_3694) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNATDQLEQKVNEFFVNAKKN------KPEWREEQMEVIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLEMDSPSQPVN----------------- --NHHVHSHTTTET-----------------------------------ERKYSTPLHH-TTEHIPEKKFKSEALLSTLT SDASKENTPGCRTNSTPSSANSVYS----------------------------VNSSQPLAS------------------ -----------------------------------------------YNLSALPAGPGAGAGAITMAAAQAVQATAQMKD GRRTSSLKASYEAIKN-----NDFQLGREFSLSRDGTGYSSS-ALASTLTQTLAPNTTSDSR-GRKSKSSIK-------- --------------------SSNHQSS-----------------SSSSSSS---LSSCSSSSALAQELSQQASVLPEPEA N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNTDCPIEWFHYGCVGLSEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Gallus_gallus-ING3(ENSGALP_14665) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------DAMDQLEQRVNEFFMNAKKN------KPEWREEQMTSIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKHNPSSHHGATDHVPEKKFKSEALLSTLT SDASKENTPGCRNNNSSSSSNNAYN----------------------------TNSSQPLAS------------------ -----------------------------------------------YNLGSLSSG--SGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGREFSLSRDSTGYSSS-ALASTLTQTLSSS-STDSRSGRKSKNNNK-------- --------------------SSSQQSS-----------------SSSSSSSLS---SCSSSSALAQELSQQTAVIPESDS N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Monodelphis_domestica-ING3(ENSMODP_34509) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMTSIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHTTTDHIPEKKFKSEALLSTLT SDASKENTPGCRNSNSSTSSNNAYN----------------------------VNSSQPLAS------------------ -----------------------------------------------YNIGSLSSG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGREFSLARESTGYSSS-ALASTLTQTISSA-ATDSRSGRKSKNNLD-------- --------------------DTSDAEI-----------------FLKNGDGELREFVLDSLSLLTQELSQQTTAIPESDS N---------------------------------------------------------------NQVDWTYDPNEPRYCI CNQVSMWKMVGCDTQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Ornithorhynchus_anatinus-ING3(ENSOANP_8991) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------LEICTRLLDVEISDIPL--KNAMDQLEQRVSEFFMNAKKN------KPEWREEQMTSIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHATADHVPEKKFKSEALLSTLT SDASKENTPGCRNNNSSTSSNNAYN----------------------------VNSSQPLAS------------------ -----------------------------------------------YNIGSLSSG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGREFSLARESTGYSSS-ALASTLTQTLSS--TTDSRSGRKSNNNNL-------- --------------------VSLTVAQ-----------------FSVVMPICR---SNNKSSTLAQELSQQTAAIPESDS N---------------------------------------------------------------NQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLSEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Macaca_mulatta-ING3(ENSMMUP_3268) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMASIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHTTTDHIPEKKFKSEALLSTLT SDASKENTLGCRNNNSTASSNNAYN----------------------------VNSSQPLGS------------------ -----------------------------------------------YNIGSLSTG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGKEFSMARETVGYSSSSALMTTLTQNASSS-AADSRSGRKSK------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------- >Mus_musculus-ING3(ENSMUSP_31680) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMASIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHAAADHIPEKKFKSEALLSTLT SDASKENTLGCRNNNSTASCNNAYN----------------------------VNSSQPLAS------------------ -----------------------------------------------YNIGSLSSG--AGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGKEFSIPRETAGYSSSSALMTTLTQNASSS-ATDSRSGRKSKNNTK-------- --------------------SSSQQSS-----------------SSSSSSSSSSLSLCSSSSTVVQEVSQQATVVPESDS N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSRHK------------------- >Homo_sapiens-ING3(ENSP_320566) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMASIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHTTTDHIPEKKFKSEALLSTLT SDASKENTLGCRNNNSTASSNNAYN----------------------------VNSSQPLGS------------------ -----------------------------------------------YNIGSLSSG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGKEFSMARETVGYSSSSALMTTLTQNASSS-AADSRSGRKSKNNNK-------- --------------------SSSQQSS-----------------SSSSSSS---LSSCSSSSTVVQEISQQTTVVPESDS N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Canis_familiaris-ING3(ENSCAFP_5192) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMASIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHTTTDHIPEKKFKSEALLSTLT SDASKENTLGCRNNNSTTSSNNAYN----------------------------VNSSQPLAS------------------ -----------------------------------------------YNIGSLSSG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSS-AADSRSGRKSKNNNK-------- --------------------SSSQQSS-----------------SSSSSSS---LSSCSSSSTVVQEISQQTTVVPESDS N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Equus_caballus-ING3(ENSECAP_6448) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MLYLEDYLEMIEQLP-MDLRDRFTEMREMDLQV--QNAMDQLEQRVSEFFMNAKKN------KPEWREEQMASIKKDYYK ALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVN----------------- --NHHAHSHTPVE------------------------------------KRKYNPTSHHTTTDHIPEKKFKSEALLSTLT SDASKENTLGCRNNNSTASSNNAYN----------------------------VNSSQPLAS------------------ -----------------------------------------------YNIGSLSSG--TGAGAITMAAAQAVQATAQMKE GRRTSSLKASYEAFKN-----NDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSS-AADSRSGRKSKNNNK-------- --------------------SSSQQSS-----------------SSSSSSS---LSSCSSSSTVVQEISQQTTVVPESDS N---------------------------------------------------------------SQVDWTYDPNEPRYCI CNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK------------------- >Branchiostoma_floridae-ING1(XP_002596469) -------------------------------------------------------------------------------- ----------------------------------------------------------MPGNEDGGSKGLTPRVVDELCA VTYVEDYLDCIESLP-DDLQRNVSQLREIDAQF--QEVMKEIEESQERYV-NES--------DPIVRRRKLIQIQRGLVK SQELGDEKLQLVSAMVDMVENRARQLDEDQRNLDAGKDTDHPPEIVKPE------------------------------- --------------------------------------------------------------QPPERNNKRSRRQRS--- -HEKRE--------AQDKDIPSDNP------------------------------------------------------- -------------------------------------------------------------------------KPVKKKK R--------------------------------------SKAKAEKQREERESSPS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------ELAIDPNEPRYCL CNQVSYGEMIGCDNEECEIEWFHFDCVSLHNKPKGKWYCPKCRGDKATERGPGIDKKSHGHDADEKKKRGGNR >Strongylocentrotus_purpuratus-ING1(XP_792118) -------------------------------------------------------------------------------- ---------------------------------------------------------------------MSHTAANMFQT TSYVEDYLDCIESLP-NDLQRSVSQIREIDSTY--QSVLREIKQLYETLTTKDL--------DNHNKRRTLIRLHRCLIQ SQELGDEKLQFASQISEIVENRLRQMNMNRTHLEITEKPEHPPDPPSKTKKAVP-------------------------- -----------------------------------------------------------VVVEPEAPAEKASKRLRR--- -SRNSD--------VVKEKDNHRVP------------------------------------------------------- --------------------------------------------------------------------------QQNDNP KA-------------------------------------KKKKRNKTKE-RDILPI------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DPPIDPNEPTYCL CQQVSYGDMVGCDNKDCPYEWFHFGCVGLSTKPKGKWYCPKCLPEVKKK------------------------ >Mus_musculus-ING1(ENSMUSP_62593) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLSPANGE-QIHL VNYVEDYLDSIESLP-FDLQRNVSLMREIDAKY--QEILKELDDYYEKFK-RET--------DGTQKRRVLHCIQRALIR SQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEA---------------------- ------------------------------------------------------------ITQADKPNNKRSRRQRN--- -NENRE---NASNNHDHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKS--------KKERAYNR >Equus_caballus-ING1(ENSECAP_2300) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------EILKELDDYYEKFK-RET--------DGTQKRRVLHCIQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAHQEVSDTTGHSGKAGQDKSKNET---------------------- ------------------------------------------------------------ITQAEKPNNKRSRRQRN--- -NENRE---NAANNHEHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKA S--------------------------------------KKKKRSKAKAEREASPT------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Canis_familiaris-ING1(ENSCAFP_35494) LSPMECPYQS-AAQLLVAADEGGQCAVTGTGLRFRCLLF--SGGRGAGGGPLDLNVFGSPGLRPPIGP--------SALL CSDWRPAWPPPCGPAIPADGGSGAG-RVARWPPPHWLGARPRPCPSGARSRPLPAAEGRARARTPRTPRTRSRGR-GWEG SRCQAPCLSALGYCRGFQEKNLITYRYSTQWCI--KEILKELDEYYEKFK-RET--------DSVQKRRVLHCIQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAHQEVNDTTGHSGKAGQDKSKSET---------------------- ------------------------------------------------------------ITQAEKSNNKRSRRQRN--- -NENRE---NAANNHDHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKA S--------------------------------------KKKKRSKAKAEREASPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Monodelphis_domestica-ING1(ENSMODP_5573) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLSPANGE-QIHL VNYVEDYLDSIESLP-FDLQRNVSLMREIDAKY--QEILKELDEYYEKFK-RET--------DSVQKRRVLHCIQRSLIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFETCQEANDTTGNSGKTSQDKSKNET---------------------- ------------------------------------------------------------ITQAEKPNNKRSRRQRN--- -NENRE---NASNNHDHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Gallus_gallus-ING1(ENSGALP_27168) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------AEILKDLDDYYEKFK-REN--------DAVQKRRMLHCIQRALIR SQELGDEKIQIVSQMVELVENRSRQVDSHVELFETCQETNDTTGNSGKASQDKSKNET---------------------- ------------------------------------------------------------IAQSEKPNNKRSRRQRN--- -NENRE---NASNNHDHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPP------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Taeniopygia_guttata-ING1(ENSTGUP_9109) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLSPANGD-QLHL VNYVEDYLDSIESMP-FDLQRNVSLMREIDAKY--QEILKDLDDYYEKFK-RET--------DAVQKRRMLHCIQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFETCQETNDTTGNSGKASQDKSKNEA---------------------- ------------------------------------------------------------IAQAEKPNNKRSRRQRN--- -NENRE---NASNNHDHDDITSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPP------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Ornithorhynchus_anatinus-ING1(ENSOANP_24605) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLSPANGE-QLHL VNYVEDYLDSIESLP-FDLQRNVSLMREIDAKY--QDILKELDDYYEKFK-RET--------DPGQKRRVLHCIQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFETRQEANDPTGNGGKAGPEKAKNET---------------------- ------------------------------------------------------------MGQAEKPNNKRSRRQRN--- -NENRE---NASNNHDHDDLTSGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREPSPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Homo_sapiens-ING1(ENSP_364929) MSFVECPYHSPAERLVAEADEGGPSAITGMGLCFRCLLFSFSGRSGVEGGRVDLNVFGSLGLQPWIGSSRCWGGPCSSAL RCGWFSSWPPPSKSAIPIGGGSRGAGRVSRWPPPHWLEAWRVSPLPLSPLSPATFGRG-------FIAVAVIPGL-WARG RGCSSDRLPRPAGPARRQFQAASLLTRGWGRAWPWKQILKELDECYERFS-RET--------DGAQKRRMLHCVQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEA---------------------- ------------------------------------------------------------AAQADKPNSKRSRRQRN--- -NENRE---NASSNHDHDDGASGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Macaca_mulatta-ING1(ENSMMUP_30046) -SFVECPYHSPAERLVAEADEGGCSAITGMGLCFRCLLFSFSGRSGVE--VVDLNVFGSLGLQPRIGPCRCWGGLCSSAL RCGWFSSWPPPSKSAIPICGGSRGARRVSRWPPPHWLEGRLVSPRPLSPLSTATFGRG-------VMAVTGTPGL-GARG RGCSSGRLPRPARPARRQSQAASLLTRGRGRAWPGKQILKELDECYERFS-RET--------DGAQKRRMLHCVQRALIR SQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEA---------------------- ------------------------------------------------------------AAQAEKPNSKRSRRQRN--- -NENRE---NASSNHDHEDSASGTP------------------------------------------------------- -------------------------------------------------------------------------KEKKAKT S--------------------------------------KKKKRSKAKAEREASPA------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPNEPTYCL CNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKS--------KKERAYNR >Takifugu_rubripes-ING1(ENSTRUP_25019) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLNPSNGDPNQVV VNYVEEYLELVESLP-CDLQRSVSLMKEIDAKY--QDVLKELDDAYERYR-RES--------DSLQRRKLQMSIQRALIR SQELGDEKIQIAGQMVELVENRTRQIDWHSQLLLSSQEVPESHVPTTTSMTTSAASMMSSSSSTSNVTPGKTS------- ------------------------------------------------HHDKKRDEITPGSAGGDKSGGKRSRRQKN--- -GDTRD---SYGGMDHSDEVSLGAS------------------------------------------------------- -------------------------------------------------------------------------REKRAKT SS-------------------------------------KKKKRSKGKSEREVSPP------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPDEPTYCL CEQVSYGEMIGCDNDECSIEWFHFSCVGLHHKPKGKWYCPKCRGENEKTMDKALERA--------KKERAYNR >Oryzias_latipes-ING1(ENSORLP_22617) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLNSANGDPGHVV VNYVEEYLDLVESLP-FDLQRSVSLMREIDAKY--QDVLKELDDAYERYR-RES--------DSLQRRKLQLSIQRALIR SQELGDEKIQIAGQMVEMVENRTRQIDWHSELLLSSQEVPESHVSTPASLTTTATSLM---------------------- ------------------------------------------------------------SSSVDKAGGKRSRRQKN--- -GENRE---SYAGLDHPEDVGA--S------------------------------------------------------- -------------------------------------------------------------------------REKRAKT SS-------------------------------------KKKKRSKGKSEREVSPP------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPDEPTYCL CEQVSYGEMIGCDNDECPIEWFHFSCVGLHHKPKGKWYCPKCRGENEKTMDKALERA--------KKERAYNR >Gasterosteus_aculeatus-ING1(ENSGACP_4599) -------------------------------------------------------------------------------- -------------------------------------------------------------------MLNPANGDPSHAV VNYVEEYLDLVESLP-FDLQRSVSLMKEIDAKY--QDVLKELDDAYERYR-RES--------DSLQRRKLQLSIQRALIR SQELGDEKIQIAGQMVELVENRTRQMDWHSELLLSSQEVPKRDEVTPS-------------------------------- ------------------------------------------------------------SAAGDKAGGKRSRRQKN--- -GENRE---SYGGLDQAEEVGAGAS------------------------------------------------------- -------------------------------------------------------------------------REKRAKT SS-------------------------------------KKKKRSKGKSEREVSPP------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DLPIDPDEPTYCL CEQVSYGEMIGCDNDECPIEWFHFSCVGLHHKPKGKWYCPKCRGENEKTMDKALERA--------KKERAYN- >Oryzias_latipes-ING2(ENSORLP_15380) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------EVLKEVDEVFEKYK-DEE--------DAAQRKRLQIQLQRALIS SQELGDEKIHVVTQMTELVENRSRQMDSHSLCLQESCDAERLPVERRSSVQESP-------------------------- --------------------------------------------------------------APERASNRRPRRQRN--- -SESRDSSLPSANGSLLDDPLDDPPLP----------------------------------------------------- ------------------------------------------------------------------AQ-----REKKSKS S--------------------------------------KKKKR-KAKQERDTSPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DFAIDPNEPTYCL CEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMDKSLDKN--------RKDRRSR- >Gasterosteus_aculeatus-ING2(ENSGACP_1097) -------------------------------------------------------------------------------- -------------------------------------------MLG----------------------HHYPNADKSQQL VNYVEDYLECVESLP-LDIQRNVSLLREIDAKY--QEVLKEVDEVFEKYK-SEQ--------DAAQRKRLQIQLQRALII SQELGDEKIHVVTQMTELVENRSRQMDSHSICLQEPSEAERLTTERRTSVQDSS-------------------------- --------------------------------------------------------------APERTSARRRDASAT--- -ARAATSSHRSGNGSVVDDPMEELPIP----------------------------------------------------- ------------------------------------------------------------------PP-----REKKSKS A--------------------------------------KKKKR-KAKQERDASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DFAIDPNEPTYCL CEQVSYGEMIGCDNDQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMDKSLDKN--------RKDRRSR- >Takifugu_rubripes-ING2(ENSTRUP_35350) -------------------------------------------------------------------------------- -------------------------------------------MLG----------------------HQYPNADKSQQL VSYVEDYLECVESLP-LDIQRNVSLLREIDAKY--QDVLKEVDEVFEKYK-GEQ--------DVSQKKRLQTQLQRALII SQELGDEKIHVVTQMTELIENCSRQMDSHSLYLQGPSEPERLSAERRSSLQDPL-------------------------- --------------------------------------------------------------APERSSARRPRRQRN--- -SESRESSQPSANGSLVEDSLEELSNL----------------------------------------------------- ------------------------------------------------------------------PS-----KEKKSKS V--------------------------------------KKKKR-KAKQERDNSPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------DFAIDPNEPTYCL CEQVSYGEMIGCDNDQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMDKS------------RKDRRSR- >Danio_rerio-ING2(ENSDARP_9928) -------------------------------------------------------------------------------- -------------------------------------------MLG------------------HYP-----NVEKSQLV N-YVEDYLECVESLP-LDIQRNVSLLREIDTKY--QEVLKEVDEIYEKYK-KES--------DSGQRKRLQIQLQRALIS SQELGDEKIHVVTQMMEVVENRSRQIEAHSPCFLEPGDVERPPEKVR---HDPASTST---------------------- ------------------------------------------------------------NVMPERSSARRPRRQRN--- -SESRD---TCANG-ALEDLGEEPPPQ----------------------------------------------------- ------------------------------------------------------------------P------REKKSKS A--------------------------------------KKKKRSKAKQEREASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFTIDPNEPTYCL CEQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMEKSADRA--------KKDRRSR- >Gallus_gallus-ING2(ENSGALP_17323) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------RF--VEALKEIDDVYEKYK-SEN--------DPAQKKRLQQHLQRALIN SQELGDEKIQIVTQMLELVENRARQMETHSQCFQDLSENDKPLEKAK---MESC-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHIANGIDDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKRSKS S--------------------------------------KKKKRSKAKQEREVSPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMDKCTDKS--------KKDRRSR- >Taeniopygia_guttata-ING2(ENSTGUP_6752) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------F--IEALKEIDDVYEKYK-SEN--------DPVQKKRLQQHLQRALIN SQELGDEKIQIVTQMLELVENRARQMETHSQCFQDLSENEKPLEKAK---MESC-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHIANGIDDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKRSKS S--------------------------------------KKKKRSKAKQEREVSPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVGLTYKPKGKWYCPKCRGDNEKTMDKCTDKS--------KKDRRSR- >Monodelphis_domestica-ING2(ENSMODP_5181) -------------------------------------------------------------------------------- ----------------------------------------------------------------LYPAAGLLAGERGRLL SCYVQDYLECVESLP-LDMQRNVSVLREIDTKY--QEALKEIDDACEKYK-KEN--------DPHQKKRLQQNLQRALIN SQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPSESERPSDKTK---MDSS-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHIANGIEDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKKSKS A--------------------------------------KKKKRSKAKQEREASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKT--------KKDRRSR- >Homo_sapiens-ING2(ENSP_307183) -------------------------------------------------------------------------------- -------------------------------------------MLG-------------QQQQQLYSSAALLTGERSRLL TCYVQDYLECVESLP-HDMQRNVSVLRELDNKY--QETLKEIDDVYEKYK-KED--------DLNQKKRLQQLLQRALIN SQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAK---MDSS-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHMANGIEDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKKSKS A--------------------------------------KKKKRSKAKQEREASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKT--------KKDRRSR- >Macaca_mulatta-ING2(ENSMMUP_11648) -------------------------------------------------------------------------------- -------------------------------------------MLG-------------QQQQQLYSSAALLTGERSRLL TCYVQDYLECVESLP-HDMQRNVSVLRELDNKY--QETLKEIDDVYEKYK-KED--------DLNQKKRLQQLLQRALIN SQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAK---MDSS-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHMANGIEDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKKSKS A--------------------------------------KKKKRSKAKQEREASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKT--------KKDRRSR- >Equus_caballus-ING2(ENSECAP_13009) -------------------------------------------------------------------------------- -------------------------------------------MCGCWMRRRRRRRRQQQQQQQLYSSAALLTGERSRLL TCYVQDYLECVESLP-HDMQRNVSVLRELDNKY--QETLKEIDDVYEKYK-KED--------DSNQKKRLQQHLQRALIN SQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERGSDKAK---MDSS-------------------------- --------------------------------------------------------------QPERS-SRRPRRQRT--- -SESRD---LCHMTNGIEDCDDQPP------------------------------------------------------- -------------------------------------------------------------------------KEKKSKS A--------------------------------------KKKKRSKAKQEREASPV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------EFAIDPNEPTYCL CNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKT--------KKDRRSR- >Mus_musculus-ING2(ENSMUSP_79226) -------------------------------------------------------------------------------- -------------------------------------------MLG------------