>Homo_sapiens-GRB14(ENSP_263915) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTR GCAADRRKKKDLDVPEMPSIPNPFPELCC--SPFTSVLSADLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFFLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Macaca_mulatta-GRB14(ENSMMUP_20055) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----RRKKKDLDVPEMPSIPNPFPELCC--SPFTSVLSADLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKK-FLFLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Pan_troglodytes-GRB14(ENSPTRP_21504) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSASSRAAARNSPLAAQVCGATHARGDAHDLAPAPWLHARALLPLPDGTR GCAAYRRKKKDLDVPEMPSIPNPFPELCC--SPFTSVLSADLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFFLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Gorilla_gorilla-GRB14(ENSGGOP_26018) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----RRKKKDLDVPEMPSIPNPFPELCC--SPFTSVLPADLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFFLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Callithrix_jacchus-GRB14(ENSCJAP_11133) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MPSIPNPFPELCC--SPFTSVLSADLFSKE---------------------------------- ----------------------------------------------------NARKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPV-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKVYFFLRRSGLYFSTKGTSKE PRHLQFFTEFGNSDIYVSPAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSVSPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGSHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Pongo_pygmaeus-GRB14(ENSPPYP_14387) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----RRKKKDLDVPEMPSIPNPFPELCC--SPFTSVLSADLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALDVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFFLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISLMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSATN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTMDDAHTRFTDVIQLVEFYHLNKGVIPCKWKHYCVRIAL------------ ----------- >Mus_musculus-GRB14(ENSMUSP_28252) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHA--LSPASDATL RGAIDRRKMKDLDVLEKPPIPNPFPELCC--SPLTSVLSAGLFPRA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYVDDNSWTLFEHLSHIGLERTVEDHELPTEVLSHWGVEEDNKLYLRKN-YAKYEFFKNPM-YFFPEHM VS------FAAEMNGDRSPTQILQ-----VFLSSSTYPEIHGFLHAKEQGK----KSWKKAYFFLRRSGLYFSTKGTSKE PRHLQLFSEFSTSHVYMSLAGKKKHGAPTPYGFCLK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKDGMQLYQNYM HPYQG-----------------------------RSACNSQSMSPMRSVSENSLVAMDFSGEKSRVIDNPTEALSVAVEE GLAWRKKGCLR---LGNHGSPSAPSQSSAVN-------MALHRSQPWFHHRISRDEAQRLIIRQGPVDGVFLVRDSQSNP RTFVLSMSHGQKIKHYQIIPVEDDGELFHTLDDGHTKFTDLIQLVEFYQLNRGVLPCKLKHYCARMAV------------ ----------- >Rattus_norvegicus-GRB14(ENSRNOP_42214) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAAGRAGAQDSPLAVQVCRVAQGKGDAQDPAQVPGLHA--LSPASDATR RGAMDRRKAKDLEVQETPSIPNPFPELCC--SPLTSVLSAGLFPRS---------------------------------- ----------------------------------------------------NSRKKQVIRIWKEDESSRALEVPSDVTA RDVCQLLILKNHYVDDNSWTLFEHLSHTGVERTVEDHELLTEVLSHWVMEEDNKLYLRKN-YAKYEFFKNPM-YFFPEHM VS------FATEMNGDRSLTQIPQ-----MFLSSNTYPEIHGFLHAKEQGK----KSWKKAYFFLRRSGLYFSTKGTSKE PRHLQFFSEFSTSNVYMSLAGKKKHGAPTPYGFCFK-PTKA-GGPRDLKMLCAEEDQSRMCWVTAIRLLKYGMQLYQNYM HPSQA-----------------------------RSACSSQSVSPMRSVSENSLVAMDFSGQKTRVIDNPTEALSVAVEE GLAWRKKGCLR---LGNHGSPTAPSQSSAVN-------MALHRSQPWFHHRISRDEAQQLITRQGPVDGVFLVRDSQSNP RTFVLSMSHGQKIKHFQIIPVEDDGEVFHTLDDGHTKFTDLIQLVEFYQLNKGVLPCKLKHYCARMAV------------ ----------- >Oryctolagus_cuniculus-GRB14(ENSOCUP_2... -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAADRAAARDSPLAAQVCGAAQGRDDAHDPARAPWLHARALVPAPDGTR GCAADRRKKKDLDVLETPSIPNPFPELCC--SPFTSVLSAGLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYVDDHSWTLFEHLPHIGVERIIEDHELVTEVLSNWGMEEENKLFFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSTTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGSSDIYVSLTGRKKHGAPTHYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGVHGSPTASSQSSAAN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPIEDDGAMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARMAL------------ ----------- >Bos_taurus-GRB14(ENSBTAP_25686) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAAGRAAARDSPLAAQVCGAAQGRGDARDLAPAPWLHARALLPPPDATR GCAADRRKKKDLDVLEMPSIPNPFPELCC--SPFTSVLSAGLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHVGLERTIEDHELVIEVLSNWGMEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGYSSQSISPMRSISENSLVAMDFSGQKTRVIENPTEALSVAVEE GLAWRKKGCLR---LGSHGSPTASSQSSATS-------MAIHRSQPWFHHKISREEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Canis_familiaris-GRB14(ENSCAFP_15605) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----RRKKKDLDVLEMPSIPNPFPELCC--SPFTSVLSAGLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGLERTMEDHELVIEVLSNWGMEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LATHGSPTASSQSSATN-------MAIHRSQPWFHHKISREEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGELFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Loxodonta_africana-GRB14(ENSLAFP_11152) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSAAGRAAAQDSPLAVQVCGAGQGRGDARDLAPAPWLHARALLPPPDGTR -FSWCRRKKKELDVLEMPSIPNPFPELCC--SPFTSVLSAGLFPKV---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYVDDHSWTLFEHLPHIGLERTIEDHELVIEVLSNWGMEEENKLYFRKN-YAKYEFFKNPV-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFK-PNKA-GGPRDLKMLCAEEEQSRTCWLTAIRLLKYGVQLYQDYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGLHGSPTASSQSSSTN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGETFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Equus_caballus-GRB14(ENSECAP_18698) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------MPSIPNPFPELCC--SPFTSVLSAGLFPKT---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPHIGLERTIEDHELVIEVLSNWGMEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGNSDIYMSLAGKKKHGAPTNYGFCFK-PHKA-GGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSTTN-------MAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDEGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARITL------------ ----------- >Pteropus_vampyrus-GRB14(ENSPVAP_7697) -------------------------------------------------------------------------------- ----------------------MTTSLQDGQRAAGRAAARDSPLAVQVCGAAQGRGDARDLAPAPWLHARALLPPPDGTR GCAADRRKKKDLDVLEMPSIPNPFPELCC--SPFTSVLSAGLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYVDDHSWTLFEHLPHIGLERIIEDHELVVEVLSNWGMEEENKLYFRKN-YAKYEFFKNPM-YFFPEHM VS------FATETNGEISPTQILQ-----IFLSSNTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSDFGNSDIYVSLAGKKKHGAPANYGFCFK-PNKA-RGPRDLTMLCADEEQSTTCWMTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGNHGSPTASSQSSATS-------LAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHAQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAKIAL------------ ----------- >Erinaceus_europaeus-GRB14(ENSEEUP_13070) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------RKKKDLDILEIPSIPNPFPELCC--SPFTSVLSAGLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYSEDETSRALEVPSDITA RDVCQLLILKNHYIDDHSWTLFEHLPRIGLERTIEDHELVIVGVSNWGMEEENKLYFRKN-YAKYEFFKSPM-YFFPEHM VS------FATETNGEISPTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFGSSDIYVSLAGKKKHGAPTTYGFCFK-PNKA-GGPRDLKMLCADEEQSRTCWVTAIRLLKYGMQLYQNYM HPYQG-----------------------------RSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEE GLAWRKKGCLR---LGTHGSPTASSQSSSTN-------IAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDEGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Monodelphis_domestica-GRB14(ENSMODP_7... -------------------------------------------------------------------------------- ----------------------MTTSLQDGQSARGKAAARGLGLA-QVCGAAQGRGDASALAVRP---QGLPCSTREGAH FCSADRRKKKDLNVLEMPSIPNPFPELCC--SPFASVFSASLFPKA---------------------------------- ----------------------------------------------------NSRKKQVIKVYNEDGTSRALEVPSDTTA RDVCQLLILKNHYINDNSWTLIEHLPHIGLERTIEDHELVMEVQSNWGMEEENKLYFRKN-YAKYEFFKNPM-NFFPEQM VS------FATETNGELSQAPILQ-----NFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYYSTKGTSKE PRHLQFFSEFGSSDIYVSLAGKKTHGAPANYGFCLK-PNKA-GGSRDLKLLYADEEQSRTCWVTAIRLLKYGMQLYQNYM HPCPG-----------------------------RSSCSSQNMSPIRSISENSLVAMDFSGHKSRVIENPTEALSVAVEE GLAWRKKGCLR---LNTHGSPTAP-QNSSTN-------LALHKAQPWFHHRISRDEAQRLIIQQGLVDGVFLVRDSQSNP KTFVLSLSHGRKIKHFQIIPLEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCSRIAL------------ ----------- >Ornithorhynchus_anatinus-GRB14(ENSOAN... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----RRKKKDLHDAEIPSIPNPFPELCC--SPFTPVFSADLLPET---------------------------------- ----------------------------------------------------DLRKKQVIKVYSEDDTSRALEVPSDITA RDVCQLLILKNHYIDDHSWTLFEYLPHMGLERTIEDHELVVEIQSKWGMEEENRLCFRKN-YAKYEFFKNPV-NFFPEHM LS------FSSETNGEITHTQILQ-----MFLSSSTYPEIHGFLHAKEQGK----KSWKKIYFLLRRSGLYFSTKGTSKE PRHLQFFSEFSSSDLYVSLAGKKMHGAPSNFGFCVK-PNKT-GGTRDLKLLCADEEQSRICWVTAIRLLKYGMQLYQNYT QPHQG-----------------------------RSGCSFQNISPMRSISENSLVAMDFSGHKGRVIENPTEALSVAVEE GLAWRRKGCLR---LNAHGSPTAS-QTSSSN-------IAIHRSQAWFHHKISRDEAQKLILQQGLVDGLFLVRDSQSNP KTFVLSLSHGQKIKHFQIIPLEDEGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCSRIAL------------ ----------- >Gallus_gallus-GRB14(ENSGALP_32500) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------QVIKVYSEDDSSKALEIPSDITA RDVCQLLILKNHYIDDHNWTLFEELTHTGLERPIEDHELVMEVQSNWGMEEENKFYFRKN-YAKYEFFKNPV-GFFPDHM IS------FSSETNATVKHSGILQ-----MFLNSSTYPEVHGYLHAKEQGK----KSWKKLYFVLRRSGLYFSTKGTSKE PRHLQFFCEFSNSDIYMSLTGRKISGAPTSYGFCFK-PNKS-GGTRDLKQLCADDEQSRTCWMTAIRLFKYGMQLYQNYM QPYQG-----------------------------RSGCSPLSVTPMRSISENSLVAMDFSGHRSRIIENPTEALSVAVEE GLAWRRRGCLR---LNSHGSPIAMSNM------------AIHRSQSWFHHKISRDEAQRLILQHGLVDGVFLVRDSQSNP KTFVLSLSHGLKIKHFQIVPLEDDGKLFYTLDDGQTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIPL------------ ----------- >Taeniopygia_guttata-GRB14(ENSTGUP_7219) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----NRRKKKGDSILEKPSIPNPFPELCC--SPFASVFSASLLPKA---------------------------------- ----------------------------------------------------TSRKKQVIKVYSEDDTSRALEVPSDITA RDVCQLLILKNHYVDDHSWTLFEQLTHTGLGRAIEDHELVLEVQSNWVMEEETKLYFRKN-YAKYEFFKNPL-SFFPDHM IS------FPSETNAALSHSGILQ-----MFLSSSTYPEIHGYLYAKEQGK----KSWKKLYFLLRRSGLYFSTKGTSKE PRHLQFFCEFSNSDMYMSLTGKKISGAPTIYGFCFK-PNKS-GGTRDLKQLCADDEQSRTCWMTAIRLLKYGMQLYQNYM QPYQG-----------------------------RSGCSPLNITPMRSISENSLVAMDFSGHRSRIIENPTEALSVAVEE GLAWRRRGCLR---LNSHGSPIAMSNMGM----------SIHRSQSWFHHKISREEAQRLILQHGLADGVFLVRDSQSNP KTFVLSLSHGLKIKHFQIVPLEDDGKLFYTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL------------ ----------- >Danio_rerio-GRB14(ENSDARP_89458) -------------------------------------------------------------------------------- ------------------------------MSAMNDSLDETHTSGSLGEKATIFRGARGGGSAVGSAFIPLRSPLQPPNA AVFKGNRKVREVDETQMGPVPDPFPELLP--S-AVSLVSECLLPWT---------------------------------- ----------------------------------------------------KNSATQVIKVYSEDNTSRAVEVPSDITA RDICQLFILKNHCVDDHSWTLFEQIPHLSIERTIEDHESVMEVQSGWGMDSHCCLYFRKN-YAKYEFFKKPL-DFFPEHM VS------ISSETNGIMNHSQLIQ-----TFLSSSSCPEIHGFLHAKEHGR----KSWKKFYFVLRRSGLYFSNKGTSKE PRHLQFIAEFSDSDVYTLLSAKKVYGAPTDYGFCVK-ASKS-SSARDLKLLCADDEQTRTCWVTAMRLFKYGMQLYQNFI QPYQ-----------------------------------KQKSSPMRSISENSLVAIDFSGHKTRVIENPSEALSVAVEE GLSWRRKSCHR---LSSHGSP-SASQSSMSS-------IAIHMAQPWFHSKLSREEAQKLITQQGLVDGVFLVRDSQSNP RTFVLSLCHTQKIKHFQIVPVEENSELFYSLDDGHTRFSDLLQLVEFYQLNRGILPCKLKHHCARISL------------ ----------- >Oryzias_latipes-GRB14(ENSORLP_21170) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MEVLSVGGMDTDCRLYFRKN-YAKYEFFKKPL-VFFPDHM FS------MSSETNGIVDASELIE-----TFVKSSTCPEVHGYLHAKDQSR----KSWKKFYFVLRRSGLYFSSKGTSKE PRHLQFFADFTDCDIYSVLSARKLYGAPTEFAFCIK-STKS-CSARDLKLLCADVEHTKTCWITAMRLLKFGMQLYQNFI QPHQ-----------------------------------KQKLSPMRSISENSLVAMDFSGQKTRVIENPSEVLSVAVEE GLSWRRKSCHR---LSSHGSP-SSSQSSVPN-------IAIHLAQPWFHGKLSREEAQRLITQQGLIDGVFLLRDSQSSP KAFVLSLCHLQKIKHFPIMPVDDDGEVFYSLDDGHTRFTDLIQLVEFHQLNRGILPCKLRHHCTQITL------------ ----------- >Takifugu_rubripes-GRB14(ENSTRUP_2093) -------------------------------------------------------------------------------- --------------------------------------------------TQILSGVRVQPGSERRVLLLL--------- -------------------------------------------------------------------------------- ---------------------------------------------------------QVIKVYNEDNTSRAIEVPNDISA RDICQLFVLKNNCIDDHSWTLFEHLSLLGIERIIEDHESVMEVLSGWGMDTDSRLYFRKN-YAKYEFFRKPL-DFFPDHM VS------ITPETNGSVDHSQLIQ-----TFLKSSSCPEIHGHLHTKELSR----KNWKKLYFVLRRSGLYFSNKGTSKE PRHLQFFASFNDSDVYTLLSAKKLHGAPSDYGFCVK-STKC-SSARDLKLLCADDEQTRTCWITAMRLLKFGMQLYQNFV QPRQ-----------------------------------KQKASPMRSISENSLVAMDFSGQRSRVIENPSEALCVAVEE GLSWRKKSCHR---LSTHGSP-STSQSLATS-------IGLHLSQSWFHGKMSREDAQRLITQQGLIDGVFLLRDSQSNP KTFVLSLCHMQRIKHFQILPMDDEGEVLFSLDDGHTRFTDLIQLVEFYQLNCGVLPCKLKHHCTRITL------------ ----------- >Tetraodon_nigroviridis-GRB14(ENSTNIP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ISAERIIEDHESVMEVLSGWGMDTDSRLYFRKN-YAKYEFFRKPL-DFFPDHM VS------ISSEMNGTVDHSQLIQ-----TFLESSSCPEIHGHLHAKELSR----KSWKKSYFILRRSGLYFSNKGTSKE PRHLQFFASFSDSDIYTILSDKKVHGAPSDYGFCVK-STKC-SSARDLKLLCADDEQTRTCWITAMRLLKYGAQLYKNYI QPHQ-----------------------------------KQKASPMRSISENSLVAMDFSGQKSRVIENPSEALSVAVEE GLSWRKKSCHR---LSTHGSP-STSQSLASS-------ISLHVGQSWFHGKMSRDDAQRLITQQGLIDGVFLLRDSQSNP KTFVLSLCHMQRIKHFQIIPMDDEGEVLLSLDDGHTRFTDLIQLVEFYQLNCGVLPCKLKHHCTRVTL------------ ----------- >Gasterosteus_aculeatus-GRB14(ENSGACP_... -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MEVLSGWAIDTECRLYFRKN-FAKYEFFRKPL-AFFPDHM VS------ISSETNGAVDHSLLIQ-----TFLNSSTCPEIHGHLHAKEQSR----KSWKKFYFVLRRSGLYFSNKGTSKE PRHLQFIADFSDSDVYTVLSAKKLHGAPTDCGFCVK-STKC-SSARDLKLLCADDEQTRTCWITAMRLLKYGMELYQNFI QPHQ-----------------------------------KQKASPMRSISENSLVAMDFSGQKSRVIENPSEALSVAVEE GLSWRRKSCHR---LSSHGSP-STCAS------------ALHLAQSWFHGKLSRDEAQRLITQQGLIDGVFLLRDSQSNP KTFV---------------------------------------------------------------------------- ----------- >Homo_sapiens-GRB10(ENSP_381793) -----------------MALAGCPDSFLHHPYY-QDKVEQT-PRSQQDPAGPGLPAQSDRLANHQ----EDDVDLEALVN DMN--ASLESLYSACS-MQ--SDTVPLLQNGQHARSQPRASGPPRSIQPQ--------------VSPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQTQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIK-PNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Macaca_mulatta-GRB10(ENSMMUP_35307) -------------------------------------------------------------------------------- -MN--ASLDSLYSACS-MQ--SDTVPLLQNGQHDRSQPRASGP-RSVQPQ--------------VSPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQSQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYSAPTDHGLCIK-PNKVRNEAKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Pan_troglodytes-GRB10(ENSPTRP_59240) -----------------MALAGCPDSFLHHPYY-QDKVKQT-PRSQQDPAGPGLPAQSDRLANHQ----EDDVDLEALVN DMN--ASLESLYSACS-MQ--SDTVPLLQNGQHARSQPRASGPPRSVQPQ--------------VSPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQTQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIK-PNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Gorilla_gorilla-GRB10(ENSGGOP_6350) -----------------MALAGCPDSFLHHPYY-QDKVEQT-PRSQQDPAGPGLPAQSDRLANHQ----EDDVDLEALVN DMN--ASLESLYSACS-MQ--SDTVPLLQNGQHARSQPRASGPPRSVQPQ--------------VSPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQTQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIK-PNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Callithrix_jacchus-GRB10(ENSCJAP_20517) -----------------MALAGCPDSFLHHPYY-QDKVEQT-PRSQQEPAGPGLPTQPDRLVNRQGKDAEDDVDLEALVN DMN--ASLES-------MQ--SDTVPLLQNGQHARSQPRASGT-RSVQPQ--------------ASPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQATAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQSQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYSAPTDHGLCIK-PNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Pongo_pygmaeus-GRB10(ENSPPYP_19679) -----------------MALAGSPDSFLHHPYY-QDKVEQT-PRSQQDPAGPGLPAQSDRLANHQ----EDDVDLEALVN DMN--ASLESLYSACS-MQ--SDTVPLLQNGQHARSQPRASGPPRSVQLQ--------------VSPRQRVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MANESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQTQLLQ-----NFLNSSSCPEIQGFLHVKELGK----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIK-PNKVRNETKELRLLCADDEQTRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Mus_musculus-GRB10(ENSMUSP_77544) -----------------------------------------------------------------------------MNN DIN--SSVESLNSACN-MQSDTDTAPLLEDGQHASNQGAASSS--RGQPQ--------------ASPRQKMQRSQPVHI- -LRRLQEEDQQLRTASLPAIPNPFPELTGAAPGSPPSVAPSSLPPPPSQPPAKHCGRCEKWIPGENTRGN----GKRKIW RWQFPPGFQLSKLTRPGLWTKTTARFSKKQPKNQCPTDTVNPVARMPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTA RDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVEST--MPSESKFLFRKN-YAKYEFFKNPV-NFFPDQM VN------WCQQSNG--GQAQLLQ-----NFLNTSSCPEIQGFLQVKEVGR----KSWKKLYVCLRRSGLYYSTKGTSKE PRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIK-PNKAKTEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYR IPQ-------------------------------RKGLPPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEE GHAWR-KRSTR---MNILSSQSPLHPSTLNA--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Rattus_norvegicus-GRB10(ENSRNOP_48487) -----------------------------------------------------------------------------MNN DIN--SSVESLNSACN-MQSDTDTVPLLENGQSASNQPSASSS--RGQPQ--------------ASPRQKMQRSQPVHIQ PLRRLQEEDQQLRTSSLPAIPNPFPELAGGAPGSPPSVAPSSLPPPPSQPPAKHCGRCDKWTPGGNTQG-----GKLKIW RCKFPPGFQLAKLTRPGLWTKTTARFSKRQPKNQCQTDTANAVSRIPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTA RDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVEST--MPSESKFLFRKN-YAKYEFFKNPV-NFFPDQM VT------WCQQSNG--GQAQLLQ-----NFLNSSSCPEIQGFLQVKEVGR----KSWKKLYVCLRRSGLYYSTKGTSKE PRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIK-PNKAKIEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKGLAPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEE GHAWR-KRSTR---MNILSSQSPLHPSTLNS--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHQQKIRNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Oryctolagus_cuniculus-GRB10(ENSOCUP_1... ------------------------------------------------PAGPGVPSSREALALSP----AEDDDLEKLVN DMN--TSLESLYSACSNMQ--SDTVPLLQNGQHTRSPPPAASA------R--------------PAPPQKVQRSQPVHIL AVRRLQDEDPQFRTSSLPAIPNPFPELSG--PGSSPVLPPASLPP--SQPVTKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILTDMTA RDLCQLLIYRSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEGT--MGSEGKFLFRKN-YAKYEFFRNPV-NFFPEQM VT------WCQQSNG--SHTQLLQ-----NFLNASSCPEIQGFLHVKELGR----KSWKRLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEESNIFSLISGKKQYSAPTDHGLCIK-PNKVRNEIKELRLLCAEDEQSRICWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLAPFATPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILSSQSPLHPNSFST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFLSLDDGNTRFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Bos_taurus-GRB10(ENSBTAP_22720) ---------------------------------------------------------------------EDDVDLEALVN DMD--ASLESLCAA-------SETVPLLHNGQHSRG---PVPRARVLQPQ--------------AAPRQRVQRSQPVSIL AVRRLQEEDLHLRTSSLPAIPNPFPELCG--PGSPPALTPGSLPP--GPAAAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYRSHCVDDNSWALVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SHTQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLYVCLRRSGLYCSTKGASKE PRHLQLLADLEDSSIFSLIAGRKQYSAPTDYGFCIK-PNRVRNEAKELRLLCAEDEQSRTCWMTACRLLKYGMLLYQNYR IPQQ------------------------------RKAMLSHFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSALST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCRLKHHCIRVAL------------ ----------- >Loxodonta_africana-GRB10(ENSLAFP_13018) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------Q-------------------------- ----------------------------------------------------------DVKVFSEDGTCKVVEILADVTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MGSESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNGSIPQTQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGRKQYSAPTDHGFCIK-PNKVRNETKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWRQKRSTR---MNVLGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQMFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Equus_caballus-GRB10(ENSECAP_21816) ---------------------------------------------------------------------EDDVDLEALVN DMN--ASLESLYSACS-MQ--SETVPLLENGQHARSQPTPSGT-RSLQPQ--------------VSPRQKVQRSQPVHIL AVRRLQEEDQQFRTSSLPAIPNPFPELCG--PGSPPVLTPGSLPP--SQATAKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYRSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--MASESKFLFRKN-YAKYEFFKNPM-NFFPEQM VT------WCQQSNG--SQTQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLYVCLRRSGLYCSTKGVSKE PRHLQLLADLEDSSVFSLIAGKKQYSAPTDYGFCIK-PNRVRNETKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDDGQMFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Monodelphis_domestica-GRB10(ENSMODP_1... ---------------------------------------------------------------------DDDVDLEALVN DMN--SSFESLYSTCS-MQ--SETAPLLQNGQHNRSQLPTSGT-SALQQQ--------------VSPKQKVQRSQPMHIL AVRRLQEEDQQFRTSSLPAIPNPFPDLCS--PTNS-VLTTSSLPQ--NQPASKQ-------------------------- ----------------------------------------------------------DVKVFSEDGTCKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHLHLGLERCLEDHELVVQVEST--MGGESKFLFRKN-YAKYEFFKNPV-NFFPEQM VA------WCQQSNGSIPQTQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLYVYLRRSGLYCSTKGTSKE PRHLQLLADLEDSNVFSLITGKKQYNAPTDYGFCIK-PNKVRNETKDLRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKAVLSHFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEE GHAWR-KRSTR---MNVLGSQSPLHPSTLST--------VIHRTQNWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKNFQILPCEDEGQMFFSLDDGNTKFTDLIQLVEFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Gallus_gallus-GRB10(ENSGALP_36287) -------------------------------------------------------------------------------N DMN--SSFESLYSTCS-MQ--SETTPLLQNGQLNRSPLPTSGS-SALQP---------------TSPRQKVQRSQPVRIM AVRRLQEEEQQFRTSSLPAIPNPFPELCS--PASSPVLAPGSLPQ--SQPANKHF------------------------- ---QGFFAFYFCFSRSSHATKGIALQSLKNPKIFLATDVVSRVLRMSHSLSLKKKKRKDVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELIVQVEST--MGSESKFLFRKN-YAKYEFFKNPM-NFFPEQM VA------WCQQTNGSIPQSQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLYVCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGKKLYNAPAEYGFCIK-PNRVRNETKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKAMLPHFSTPVRSVSENSLVAMDFSGQIGRVIENPVEAQSAAMEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKHFQILPCEDDGQIFFSLDDGNTKFSDLIQLVEFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Taeniopygia_guttata-GRB10(ENSTGUP_8212) -----------------MALAGCPDSFLHLPYR-IDNVDQTSAHGRRDLVEPGFQEPSNRISLNH---QDDDVDLEALVN DMN--SSFESLYSTCS-MQ--SETTPLLQNGQLNRSQLPSSGP-STLQP---------------LSPRQRVQRSQPVRIM AVRRLQEEEQQFRTSSLPAIPNPFPELCS--PASSPVLAPGSLPQ--SQPASKH-------------------------- ----------------------------------------------------------DVKVFSEDGTSKVVEILADMTA RDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELIVQVEST--MGSESKFLFRKN-YAKYEFFKNPM-NFFPEQM VA------WCQQTNGSIPQSQLLQ-----NFLNSSSCPEIQGFLHVKELGR----KSWKKLFMCLRRSGLYCSTKGTSKE PRHLQLLADLEDSNIFSLIAGKKLYNAPAEYGFCIK-PNRVRNETKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR IPQQ------------------------------RKAMLPHFSTPVRSVSENSLVAMDFSGQIGRVIENPAEAQSAALEE GHAWR-KRSTR---MNILGSQSPLHPSTLST--------VIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP KAFVLTLCHHQKIKHFQILPCEDDGQIFFSLDDGNTKFSDLIQLVEFYQLNKGVLPCKLKHHCIRVAL------------ ----------- >Danio_rerio-GRB10(ENSDARP_51165) -----------------MAVAGCPDYFLHHPN-YKDNVDRAANHRQADLIGPSFQQSASHNSPSH---QEDDVDLEALVN DMN--SSLESLYTSCS---VQSESTPLLHNGQPHRPSAYHTHAQPISP-------------------HQRLRRSQPMNIL AVRRLQEEAQQYRTSSLPAIPNPFPELCS--PASSPTLSSGSLPQ--CQPSDK--------------------------- ---------------------------------------------------------YIIKIFSEDGMGKVVEIPADMTA RDLCQFLVYKNHCVDDNSWALVEHHPALGLERCLEDHELVVQVQTS--MISESKFLFRKN-YAKYEFFKNPL-NFFPEQM IA------WCQETNGTIPPSQLLQ-----NFLNSSSCPEIQGYLYVKEMGR----KSWKKLYVFLRRSGLYFSTKGTSKE PRHLQLLADLEDSNVFTVITGRKLHSAPTDFEFCIK-PNKVRNEVKELRMLCAEDEQSRTCWMTAFRLFKYGILLYQNYK IHQQ------------------------------RKTLLSHFSAPVRSVSESSLVAMDFSGRIGRVIDNPVEAQSAAMEE GHAWRKKSQQR---MNILGSPSSLHPSSLSG--------VIHRTQLWFHGRISREESHKLIHQQGRVDGMFLLRDSQSNP KAFVLTLCHHQKIKHFQILLCEEDGQMFLSLDDGAVKFTDLIQLVEFYTLNRGVLPCKLKHPCTTVAL------------ ----------- >Danio_rerio-GRB10(ENSDARP_42171) -----------------MALAGCPDYFLHHPNY-QDNVDRTSSHRPSNLIGSSFQ-SSTRTSPNH---PEDDVDLEALVN DMASLSSYESIYATCE--IQHSDSAPLLHSTDSSGLHGNRVAPLPRAPSHK---------VTAPHSPAQRLRRSQPMHIH AVRRLQEEELQVRPASLPAIPNPFPELCS--PSGSPVLSPGSL----PQPSES--------------------------- ---------------------------------------------------------HIIKVFSEDGVGKVVEVTAGMMA RDVCQFLVYKSHCLDDNCWSLVEHHSLLGLERCLEDHELVVSVKAC--MPPESKFLFRKN-YAKYEFFRNPL-NFFPEQM VA------WCQESNGSIPQSQLLQ-----NFLNSSSCPEIQGFLYMKETGR----KSWKKLYMFLRRSGLYYSTKGMSKE PRHLQLLSDLEESNIFTVTTGRKMHNAPTDYQFCIK-PSKGRTELKELKMLCAEDEQSRTCWMTAFRLLKFGILLYQNYK TPHQ------------------------------RKT-ISNFTTPVRSVSENSLVAMDFSGRTGRVIDNPVEAQSAAMEE GHTWR-KRSQR---MNVLGSPSPLHPSPLSS--------VIHRTQLWFHGRIMREESHRMIMQQGQVDGLFLLRDSQSNP KAFVLTLCHHQKIKHFQILPFEEDGQVFFSLDDGSTKFTDLIHLVEFYQLNRGILPCKLKHPCTVVAL------------ ----------- >Oryzias_latipes-GRB10(ENSORLP_6700) ---------------------------------------------------------------------EDDVDLEALVN DMN--SSLESLYSSCS--GPQTESTPLLHNGQSSSSHHHHHHTSPELPSSSSL---------SADLPRTSLRRSQPMHIL AVRRLQEEELQLRTSSLPAIPNPFPELCS--PASSPVLSPGSLPP--GDPTTG--------------------------- --------------------------------------------------------KHIVKIFSEDGVGKVVEIPADMMA RDLCQLLVYKSHCLDDNSWVLVEHHPLLGLERCLEDHELVVQVQAS--MNSDGRFLFRKN-YAKYEFFRNPL-TFFPEHM VA------WCQETNHTIPPSQLLQ-----NFLSTNTCPEIQGYLYIKEVGR----KSWKKVYMFLRRSGLYCSTKGASKE PRHLQLLADLEDSNIFTVITGKKQHSAPTDFEFCIK-PNKSRGEMKELRMLCAEDEQSRTCWMTGFRLFKYGIILYQNYK LPQQ------------------------------RKPLLSPFSAPVRSVSENSLVAMDFSGRIGRVIDNPVEAQCAAMEE GHTWRKRT-QR---MNVIGSQSPLHHSTLNS--------VIHIAQLWYYGRITREESHRIIHQQGQVDGLFLVRVSQSNP KAFVLTLCHHKKIKHFQILPCEEDGQVFFSLDDGVTKFTDLIQLVEFYQLNRGVLPCKLKHPCTVVAL------------ ----------- >Takifugu_rubripes-GRB10(ENSTRUP_24701) -----------------------------------------------------------------------------LVN DMN--SSLESLYSTCS--GQQTESTPLLHNGQHVS---------PELPSSSS-----------VDSPQTGLRRSQPMHIL AVRSLQEEEQQLRTSSLPAIPNPFPELCS--PASSPVLSPGSLPP--GEPPADNFINCEKQRPVIAKRCSQKSHSWKCSG SEAFHLAKLSRTHEETGTAARFSVGERASVCLCVCEGDGLTPKMPSCSPDCCLLRAVEIVKIFSEDGMGKVVEIPADMTA RDLCQLLVYKSHCVDDNSWALVEHHPLLGLERCLEEHELVVQVQAS--MNSDSRFLFRKN-YAKYEFFRNPL-TFFPEHM VA------WCQESSRTIPPSQLLQ-----NFLASTSCPEIQGYLYVKELGR----KSWKKVYMFLRRSGLYCSTKGTSKE PRHLQLVADLEDSNIFTVITGKKQHGAPTDYGFCVK-PNKGRGEMKELRMFCAEDEQGRTCWMTAFRLFKYGIVLYQNYK IPQQ------------------------------RKTLLSHFSAPVRSVSENSLVAMDFSGRIGRVIDNPVEAQSAAMEE GHAWRKRS-QR---MNILGSHSPLHHSSLNS--------VIHIAQLWFHGRISREESHRIIHQQGQVDGLFLVRVSQSNP KAFVLTLCHHQKIKHFQILPCEEDGQVFFSLDDGATKFTDLIQLVEFYQLNRGVLPCKLKHPCTAVAL------------ ----------- >Tetraodon_nigroviridis-GRB10(ENSTNIP_... -----------------MAVAGCPEYFPHHSNYKQESMDRTSSRRSEGLIVPSFQRQASQTLPHH---HDDDVDLEQLVN DMN--SSMENVYST------QADTALLLNNGHGHAPNYHHHHPHAHPAYPG-------PAIVASSPSRDRLRHSQPMHIQ AVRCLREE-QQLRPASLPAIPNPFPELCS--PAGSPVLSP-------TQASNN--------------------------- ---------------------------------------------------------HIVKVWSEDGAGKVVEIPADMTA RDVCQLLVYKNHCLDDNAWTLVEHHPILGLERCLEDHELVAQIQAS--MSSDSKFLFRKN-YAKYEFFRNPL-NFFPEQM VA------WCQESNGSIPQSQLLQ-----NFLNSSSCPEIQGYLHLKEPGR----KSWKKLYMFLRRSGLYFSTKGTSKE PRHLQLLSDLEDSGIFSVITGRKLHNAPTDFQFCIK-PSKARSDCKELKMLCAEDEQSRTCWMTAFRLLKYGIVLYQSYN VPQQ------------------------------RKSSLPPFSAPVRSVSENSLVAMDFSGRTGRIIDNPVEAQSAALEE GQTWRQKRSQR---MNVLGSPSPMHPSSLSA--------AIHRTQVWFHGRIVREEAHKMIIQQGQVDGLFLLRDSQSNP RAFVLTLCHHQKIKHFQILPCEEDGQVFFSLDDGSTKFTDLIHLVDFYQLNRGVLPCKLKHPCTAVAL------------ ----------- >Tetraodon_nigroviridis-GRB10(ENSTNIP_(2) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------IVKIFSEDGMGKVVEIPADMTA RDLCQLLVYKSHCVDDNSWALVEHHPLVGLERCLEDHELVVQVQAS--MNSDSRFLFRKN-YAKYEFFRNPLQTFFPEHM VA------WCQESSRTIPPSQLLQ-----NFLASTSCPEIQGYLYVKELGR----KSWKKVYMFLRRSGLYCSTKGTSKE PRHLQLVADLEDSNIFTVITGKKQHGAPTDYSFCIK-PNKGRGEMKELRMLCAEDEQGRTCWMTAFRLFKYGIVLYQNYK IPQQ------------------------------RKTLLSHFSAPVRSVSENSLVAMDFSGRIGRVIDNPIEAQSAAMEE GHAWRVR--RR---SSLSATAN---TSDFSA--------VIHIAQLWFHGRITREESHRIIHQQGQVDGLFLVRVSQSNP KAFVLTLCHHQKIKHFQILPCEEDGQVFFSLDEGATKFTDLIQLVEFYQLNRGVLPCKLKHPCTVVAL------------ ----------- >Gasterosteus_aculeatus-GRB10(ENSGACP_... -----------------MAVAGCPDYFLHHPNYQQDNIDRSSNHIQADIIGPNFQQSANRSSPNH---QDDDVDLEALVN DMN--SSLESLYSTCS--GQQTESTPLLHNGQSSSSHQLHHH--PHHTQLNQP---------RQDLSHRSLRRSQPMHIL AVRRLQEAEQQLRTSSLPAIPNPFPELCS--LANSPVLSPGSLPP--GEPSTG--------------------------- --------------------------------------------------------IYIVKVFSEDGLGKVVEIPAGMTA RDLCQLLVYKSHCVDDNSWALVEHHPLLGLERCLEDHELVIQVQAS--MSSGSRFLFRKN-YAKYEFFRNTH-TFFPEHM VA------WCQETNRTIPPSQLLQ-----NFLATSSCPEIQGYLYVKDVGR----KSWKKVYMFLRRSGLYCSAKGTSKE PRHLQFLADLEDSSIFTVITGKKLHGAPTDYEFCIKKPNKCRGESKELRMLCAEDEQGRTCWMTAFRLFKYGIVLYQNYK IPLQ------------------------------RKTLLSHFSAPVRSVSENSLVAMDFSGRIGRVIENPLEAQSAAMEE GHAWRKRS-QR---MNVLGSHSPLHHSSLSS--------VIHIAQMWFHGRITREESHRLIHQQGQVDGLFLLRVSQSNP KAFVLTLCHHQKIKHFQILPCEEDGQVFFSLDDGATKFTDLIQLVEFYQLNRGVLPCKLKHPCTVVAL------------ ----------- >Gasterosteus_aculeatus-GRB10(ENSGACP_(2) -----------------MALAGCPDYFLHHSNY-QENMDRTSARRPEELIVPGFQRSANQNLPHH---HEDDVDLEQLVN DMN--SSMESVYST------QADTARLLNNGHAAAPHQHHQQQQQHHPGHGQAHRRHTPPLLPSPPSRDRPRPSQPMHIH AVRCLQKK-HLLRPASLPAIPNPFPELCS--PDGSPVLCP-------LQTSND--------------------------- ---------------------------------------------------------HIVKVWSEDGAGKAVEIPAHMTA RDLCQLLVYKSHCVDDNAWTLVEHHHALGLERCLEDHELVVQVQAS--MSSDSKFLFRKN-YAKYEFFRNPL-NFFPEQM VA------WCQESDGSIPQSQLLQ-----NFLNSSSCPEIQGYLHVKEPGR----RSWKKLYMFLRRSGLYYSTKGTSKE PRHLQLLSDLEDSNIFTVITGRKLHNAPTDYHFCIK-PSKVTSDGKELKMLCAEDEQSRTCWMTAFRLLKYGILLYQSYN VPQQ------------------------------RKSNLPPFSAPVRSASENSLVAMDFSGRTGRVIENPLEAQSAALEE GQSWR-KRSQR---MNVLGSPSPLHPSSLST--------VIHRTQIWFHGRVVREDAHKMIIQQGQVDGLFLLRDSQSNP KAFVLTLCHHQKIKHFQILPCEEDGQVFFSLDDGATKFTDLIHLVEFYQLNRGLLPCKLKHPCTAVAL------------ ----------- >Homo_sapiens-GRB7(ENSP_403459) -----------------------------------------------------------------------------MGK WRPGQGHTTGSVKPLSCSDAMELDLSPPHLSSSPEDLCPAPGTPPGTPRPPD------------TPLPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEE AQAWRKK------TNHRLSLPMPASGTSLSA--------AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Macaca_mulatta-GRB7(ENSMMUP_27343) -------------------------------------------------------------------------------- --------------------MELDLSPPHLGSSPEDLCPAPGTPPGTPRPPD------------TPLPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYRNYQ QAQSR-----------------------------HLRPPCLGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSVALEE AHAWRKK------TNHRLSLPTPASGTSLSA--------AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Pan_troglodytes-GRB7(ENSPTRP_15510) -------------------------------------------------------------------------------- --------------------MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPD------------TPLPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEE AQAWRKK------TNHRLSLPTPASGTSLSA--------AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Gorilla_gorilla-GRB7(ENSGGOP_15078) -----------------------------------------------------------------------------MGK WRPGQGHTTGSVKPLSRSDAMELDLSPPHLGSSPEDLCPAPGTPPGTPRPPD------------TPLPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEE AQAWRKK------TNHRLSLPTPASGTSLSA--------AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Callithrix_jacchus-GRB7(ENSCJAP_51727) -----------------------------------------------------------------------------MGK CRPGQGHTTGSLQP-SPSDTMELDLSPPHLGSSPEDLCPAPGAPPGNPWPPE------------GPVPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPPQSPILRGPSSVRGLLPR------------------------------- ----------------------------------------------------DASCPHVVKVYSEDGACRSVEVEAGATA RHVCEMLVQRTHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFIFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGVSHEDLIQ-----NFLNVGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGAQLYKNYQ QAQSR-----------------------------HLRPSCLGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSVALEE AQAWRKK------TNHRLSLPTPASGTSLSA--------AIHRTQLWFHGRISREESQQLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Pongo_pygmaeus-GRB7(ENSPPYP_9525) -------------------------------------------------------------------------------- --------------------MELDLSPPHLGSSPEDLCPAPGTPPGTPRPPD------------TPLPEEVKRSQPLLIP TTGRKLRE-EERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYMVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLHPSCLGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSVALEE AQAWRKK------TNHRLSLPTPASGTSLSA--------AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Mus_musculus-GRB7(ENSMUSP_19456) -------------------------------------------------------------------------------- --------------------MELDLSPTHLSSSPEDVCPTPATPPETPPPPD------------NPPPGDVKRSQPLPIP SS-RKLRE-EEFQATSLPSIPNPFPELCSPPSQKPILGGSSGARGLLPR------------------------------- ----------------------------------------------------DSSRLCVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDESWGLVESHPYLALERGLEDHEFVVEVQEAWPVGGDSRFIFRKN-FAKYELFKSPPHTLFPEKM VS------SCLDAQTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGRGSGRKLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLHIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLRLSYLGSPPLRSVSDNTLVAMDFSGHAGRVIDNPREALSAAMEE AQAWRKK------TNHRLSLPTTCSGSSLSA--------AIHRTQPWFHGRISREESQRLIGQQGLVDGVFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEDEGCLYFSMDEGQTRFTDLLQLVEFHQLNRGILPCLLRHCCARVAL------------ ----------- >Rattus_norvegicus-GRB7(ENSRNOP_9299) -------------------------------------------------------------------------------- --------------------MELDLSPSHLSSSPEDVCPTPGTPPETPPPPD------------NPPPGDVKRSQPLPIP SS-RKLRE-EEFQATSLPSIPNPFPELCSPPSQKPILGGSSGARGLLPR------------------------------- ----------------------------------------------------DSSRLCVVKVYSEDGACRSVEVAAGATA RHVCEMLVQRAHALSDENWGLVECHPYLALERGLEDHESVVEVQEAWPVGGDSRFIFRKN-FAKYELFKSPPHTLFPEKM VS------SCLDTPTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGRGSGRKLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADINESNVYVVTQGRKLYGIPTDFGFCVK-PNKLRNGHKGLHIFCSEDEQSRTCWLSAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLRLSYLGSPPLRSVSDNTLVAMDFSGHAGRVIENPQEALSAATEE AQAWRKK------TNHRLSLPTPCSGLSLSA--------AIHRTQPWFHGRISREESQRLIGQQGLVDGVFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEDEGCLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCARVAL------------ ----------- >Oryctolagus_cuniculus-GRB7(ENSOCUP_22... -------------------------------------------------------------------------------- --------------------MELDLSPPQLSSSPEDLCPVPGTPPGTPPLPD------------ASLPGEVKRSQPLPIP PS-RRLRE-EGLQASSLPSIPNPFPELCSPPSQAPILGGSASARGLLPR------------------------------- ----------------------------------------------------DTS--HVVKVYSEDGACRSVEVAAGATA RHVCEMLVHRAHALNDENWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKH-FAKYELFKSSPHSLFPEKM VS------SCVDAHAGVSHEDLIPGGGPRNFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCIK-PNKLRSGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLRPPYLGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSAALEE AQAWRKK------TNHRLSLPTPCSGTSLSA--------AIHRTQPWFHGRISREESQQLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGCLYYSMDDGHTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Bos_taurus-GRB7(ENSBTAP_23091) -------------------------------------------------------------------------------- --------------------MELGLSPLHLSSSPEDLYLASGTPPGTPPPLD------------APLSGEVKRSQPLPIP TSRKLLRE-EELQSTSLPSIPNPFPELCSPSSQSPILGGSSSARGLLPR------------------------------- ----------------------------------------------------DTSCPHVIKVYSEDGTCRSVEVATGATA RYVCEMLVQRSHALSDENWGLVECHPYLALERALEDHESVAEVQAAWPIGGDSRIVFRKN-FAKYELFKSTPHSLFPEKM VS------SCLDAHTGMSHEDVIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCIK-PNKLRNGHKGLRLFCTEDERSRSCWLAAFRLFKFGVQLYKNYQ QTLCR-----------------------------HMCPPCGGSPPSRSVSDDTLVAMDFSGHAGRVIENPREALSAALEE AQAWRKK------TNHRLSLPTPSSGTSLSA--------AIHRTQPWFHGRISREESQRLIRQQGLVDGLFLVRESQRNP QGFVLSLCHVQKVKHYLILPSEEEGRLYFSMDDGLTRFTDLLQLVEFHQLNRGILPCLLRYCCTRVAL------------ ----------- >Canis_familiaris-GRB7(ENSCAFP_24052) -------------------------------------------------------------------------------- --------------------MELGLSPPHLSSSPEDLYLAPGTPPGTPPPPD------------APLPGEVKRSQPLPIP TSRNLLRE-EELRSTSLPSIPNPFPELCSPPSQTPILGGSSGARGLLPR------------------------------- ----------------------------------------------------DASCPHVVKVYSEDGACRSVEVAAGATA RYVCEMLVQRAHALSDENWGLVECHPHLALERGLEDHESVVEVQAAWPIGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCVDAHTGLSHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTEGRKLYGMPTDFGFCIK-PNKLRNGHKGLRVFCSEDEQSRTCWLAAFRLFKYGAQLYKNYQ QAQSR-----------------------------HLRPSCVGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSAALEE AQAWRK--------NHRLSLPTPGSGTSLSA--------AIHRTQPWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Loxodonta_africana-GRB7(ENSLAFP_13709) -------------------------------------------------------------------------------- --------------------MELDLSPPHLSSSPEDLCAIPGTPPGTPPPPS------------APLSGEVKRSQPLSIP AS-RKFRE-EELQTTSLPSIPNPFPELCSP-SQSPILGGTSSARGLLPR------------------------------- ----------------------------------------------------DASRPHVVKVYSEDEACRSVEVAAGATA RHVCEMLVQRAHALSDENWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKN-FAKYELFKNSPHSLFPEKM VS------SCLDANTGISHEDLIQ-----NFLNSGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGMQLYKNYQ QAQSR-----------------------------HLRPSCLGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSAALEE AQAWRKK------TNHRLSLPTPSSGSSLSA--------AIHRTQPWFHGRISREESQRLIRQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCIRVAL------------ ----------- >Equus_caballus-GRB7(ENSECAP_10909) -------------------------------------------------------------------------------- --------------------MELGLSPPHPSSFPEDLYPAPGTPPGTPPPPD------------PPLPGEVKRSQPLPIP TSRKLLRE-EELRASSLPSIPNPFPELCSPPSQTPILGGSCSARGLLPR------------------------------- ----------------------------------------------------DASCPHVVKVYSEDGACRSVEVAAGATA RYVCEMLVQRAHALSDENWGLVECHPHLALERGLEDHESVVEVQAAWPIGGDSRFIFRKN-FAKYELFKSSPHALFPEKM VS------SCFDAHTGISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKFYGMPTDFGFCIK-PNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGMQLYKNYQ QAQSR-----------------------------HLRPSCVGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSAALEE AQAWRKK------TNHRLSLPTPCSGSSLSA--------AIHRTQPWFHGRISREESQRLIGQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL------------ ----------- >Pteropus_vampyrus-GRB7(ENSPVAP_8060) -------------------------------------------------------------------------------- --------------------MELGLSPPHSSSSPEDLYPAPGTPPGTPPPPD------------VPLPGEVKRSQPLPIP NSRKLLRE-EELRTTSLPSIPNPFPELCSPSSQTPILGGPSSARGLLPR------------------------------- ----------------------------------------------------DASCLHVVKVYSEDGACRSVEVAAGATV RYVCEMLVQRAHALSDENWGLVECHPHLALERGLEDHESVVEVQAAWPIGGDSRFVFRKN-FAKYELFKSSPHSLFPEKM VS------SCLDTQTDISHEDLIQ-----NFLNAGSFPEIQGFLQLRGSGR----KLWKRFFCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYVVTQGRKLYGLPTDFGFCIK-----------------------TCWLAAFRLFKYGVQLYKNYQ QAQSR-----------------------------HLRPSCVGSPPLRSVSDNTLVAMDFSGHAGRVIENPREALSVALEE AHAWRKK------TNHRLSLPTPCSGTSLSA--------AIHRTQPWFHGRISREESQRLIAQQGLVDGLFLVRESQRNP QGFVLSLCHLQKVKHYLILP---------SMDEGQTRFTDLLQLVEFHQLNRGILPCFLRHCCTCVAL------------ ----------- >Monodelphis_domestica-GRB7(ENSMODP_33... -------------------------------------------------------------------------------- --------------------MDLDLSLPHLSNSSDDPSPEPGTPPGTPPGSN------------AHLPGELKRSQPLSIQ AS-RKLRE-EELRASSLPAIPNPFPELCSPPSQSPILGAPSSGRAFLPR------------------------------- ----------------------------------------------------ATSGTHVVKVYSEDGACRSVEVAADATA RHVCEMLVQRVHALSDESWGLVECFPHLALERGLEDHESVIEVQSAWPVGGDNRFVFRKN-FAKYELFKSSPHSLFPEVM VS------SCLDTNTRMSHEELIQ-----NFLNAGSCPEIQGFLQLRGSGR----KHWKRFYCFLRRSGLYYSTKGTSKD PRHLQYVADVNESNVYLVTKGRKLYGMPTDFGFCVK-PNKLRS-PKGLRIFCSEDEQSRSCWVAAFRLFKYGMQLYKNYQ QMQSR-----------------------------RIRPSWFGPTPLRSVSDNTLVAMDFSGHGGRVIENPREALSAALEE AQAWRKK------TNHRYSLPTPCPSSTFSS--------AIHRSQPWFHGRISREDTQRLIGEQGLVDGVFLVRESQRNP QGFVLSLCHLQKVKHYLILPSEDEGRLYFSMDEGQTRFTDLLQLVEFHQLNRGILPCPLRHCCTRVAL------------ ----------- >Ornithorhynchus_anatinus-GRB7(ENSOANP... -------------------------------------------------------------------------------- --------------------MELAISLTQHASPPDEL--EKGLSLG-PPPRS------------PPVPGELKRSQPLFIQ CG-RKSKE-EELRASSLPSIPNPFPELCNPPAHSPILASSSGGRGLLSY------------------------------- ----------------------------------------------------DASGPNSFRLP---------IVTFNRSN QSALEMDAN--KGMSHEELIQVRDRPPRPQSPPPHSESSISPDFCSW--AGPVHFASHSSPLQEVIMQERHPITPMPSFI HSYL----SLPKSPASLPFPDPPT--RRQNFLNVGSCPEIQGFLQLREAGR----KLWKRSYFFLRRSGLYFSTKGTSKD PRHLQYLADVNETNVYVVTQGRKLYGTPTDFGFCLK-KGSLRNSQKG-----GDRQQNKTRSCSPWGLFKYGVQLYKNYQ QVQSR-----------------------------HSQLAWFGPTPLRSVSDNTLVAMDFSGCAGRVIKNPPEALSAALEE AQALTKKK-----TTHRYSLPTPCPGTTLSA--------ALHRTQPWFHGRLSREDTQRLIWQQGLVDG----------- -------------------------------------------------------------------------------- ----------- >Taeniopygia_guttata-GRB7(ENSTGUP_2306) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -RHLQYFADLTESNIYYVTQGKKLYGTPTEFGFCIK-PHKVRSGAKGLKLLCSEDEQSRSCWVAAFRLFKYGMQLYRNYQ QAQAR-----------------------------LSQPPWIGPTPLRSVSDNALVAMDFSG------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------- >Ciona_savignyi-GRB7(ENSCSAVP_5223) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------LSTERYVEDYEIIDEIWGNQEPDIISRFCLNKS-PSKFSILQSPE-LCLPNGM LTSPGLSSNSSEIGSTVRRLQMQH-----VLTKT--APELSGWLHVREVGR----SSWKKLFCVLRNSGLYHSSKSTSKE PQHLVCIAEV----WYPINNKKPTSSAPHPHCFCLK-PKSY-KSGAIIRWFCAESSHLRLAWISGLRLTMNGSRFYESYL SARR------------------------------LGQTNLVRSSSDRSINRHDFAPMDFRGETGRVIQDPKEVAMLELEQ QSSWRRRLIN--RTLTGQGEGADIVLTTSTT--------AIHQTQPWFYGKITREQANDEVQRNGNIDGLFLVRDSRTIP GGIVITVCHNQKCRHIPITQIKRCGQSFYTADNGETRFVDMIQLIDFHRLNRGSLPCLLLYECPGSQL------------ ----------- >Ciona_intestinalis-GRB7(ENSCINP_6852) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------MSAWISGLRLTMNGSRFYESYL SARR------------------------------QSQSNLVRSSSDRTINRHDFAAMDFRGETGRVIHDPKEVAMLELEQ QSSWRRRLIN--RTITGQASDRNIVGSSAPTKQVAFFARAIHQTQTWFYGKITREEATEELHRNGNVDGLFLVRDSHTIP GGIVVTLCHNQKSRHIPITQIERNGQNFYTADNGETRFVDMIQLVDFHRLNKGSLPCLLLHECSHSQMS----------- ----------- >Branchiostoma_floridae-GRB7(XP_2599482) MAFGRPLCSDPWCRGQREKAAVSAGFSPRFSGGVPPCRRRESCSRTSGGAARTRFRSSSCEKFKPILILVDDPRKESMLP CKKTSRSFCILIESFL-KTERFLKTIFTTQVTALTHQDDDVDLDALIRDMSFEAREHVMDKQPADEEHTPLLATDRDTPS NSFMSQSRPSRPVHINLNNSHSPNHRVSG--SPISSPCTPNPFPDIPVSASPTTWMISPRAASAPKKDTGSSV------- ------------------------------IKRPTETTSPMLPQRRDEYRDYREMKRVSIKIHKCDGTSKAVDVGEQMTA REVCSEVALRCRSSDERNCVLMEHIVPLGLERNLEDHERVLQVCNSWGRDSSNKLVFKKD-FRKYEVFCNPS-QFFPEDM LTNFDEIGSHSEKAEMARNMQLLN-----LLGTPGSVPNLQGWLHIRDAHK----KSWKKVMVVIKGSGLYYSTKGNSME PRHLHCYSAYSDCDIYTATQGKKVFGAPTEFCFCIK-PSKLNVEKHDIKCLCAEDERTRQCWLTAFRISKHGQLLYKNWE LSKKSWKFSDEGCPSPIISPEWNLGSYRQRMLMQESQAKEEWARSPQGPGGKNRVAMDFTGYRGRVIANPNEAVAVAVEE GQSWRKRHSSGSRALVGSPRNSPLLSPRSSR---FISPQGVHQTQPWFHHGINREEANNMMHMQGMVDGLYLVRESQTFP GTFVLTFCHDQRVKHYQIQPNVIDDKTFYSLDEGETKFGDLVQLVEFYQINRGALPHSLTHPCTGAGLRWREDDEDYGLM SFPMAKSAPAT