>Homo_sapiens-FMNL2(ENSP_288670) -----------------------------------------------------MGNAGSMDSQQTDFRAHNVPLKLPMPE PGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESVE STVESSVDKSKPWSRSIEDLHRGSNLPSPV-GNSVSRSGRHSALRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLSM-----GSEVVAGN--SVGPTMGAA SSGPLPPPPPPLP-------------------PSSDTPET---------------------------------------- -----VQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLP-SAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNK-------VTLLEA NRAKNLAITLRKAGKTADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TLLKEFILNNEGKLKKLQDDAKIAQ-------DAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDPKSPSHKSKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-NQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM >Mus_musculus-FMNL2(ENSMUSP_88472) -----------------------------------------------------MGNAGSMDSQQTDFKAHNVPLKLPMPE PGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESVE STMESTVDKSKPWSRSIEDLHRGSNLPSPV-GNSVSRSGRHSALRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-MASGTLST-----GSELAVGN--YVGSVPGAT TSGPSVPPPPPLP-------------------PSSDTSEA---------------------------------------- -----AQNGTASPPMSPPPPPPPPPPPPPPPPPP--LPGPAAETSPAPPLPPPPPPSAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKASSK-------VTLLEA NRAKNLAITLRKAGKSADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TLLKEFLLHNEGKLKKLQEDAKIAQ-------DAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDAKSPSHKSKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-NQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM >Rattus_norvegicus-FMNL2(ENSRNOP_56145) -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESVE STVESTVDKSKPWSRSIEDLHRGNNLPSPV-GNSVSRSGRHSALRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLPM-----GSDLAGGN--YVGPVPGAA SSGPSVPPPPPLP-------------------PSSDTPEA---------------------------------------- -----AQNGPASPPMSPPPP?-------PPPPPP--LPGPAAETVPAPPLPPPPPPSAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSSK-------VTLLEA NRAKNLAITLRKAGKSADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFTESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TLLKEFILHNEGKLKKLQDDAKIAQ-------DAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDPKSPSHKSKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-NQPYRRADAVRRSVRRRFDDQNLRSVNGGEITM >Bos_taurus-FMNL2(ENSBTAP_38204) -------------------------------------------------------------------------------- --------------MNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESVE STVESSVDKSKPWSRSIEDLHRGSNLPSPV-GNSVSRSGRHSALRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLPT-----GSEVAVGN--FVGPVMGAP SSGPLPPPPPPLP-------------------LSSDAPEA---------------------------------------- -----VQNGPATPPVPPPPPPPPPPPP?PPPPPPP-LPGPAAETLPAPPLPPPPPPSAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTAEEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFTESIQMLTPQLHSIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLV----------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------- >Canis_familiaris-FMNL2(ENSCAFP_8703) -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENRGLDVLVEYLSFAQYAVTFDF----------------ESVE STVESSVDKSKP--KSIENLHRRSNLPSPV-GNSVSRSRRTLRCRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLKLLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLST-----GSEAAVGN--FVGPVTGVA SSGPLPPPPPPLP-------------------PSSETPEA---------------------------------------- -----VQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLPPPPPPSAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVFRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFTESIQMLTPQLHSIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TLLKEFILNNEGKLKKLQDDAKIAQ-------DAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALLEQ-------QDPKSPSHKSKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-NQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM >Equus_caballus-FMNL2(ENSECAP_9610) -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESVE STVESSVDKSKPWSRSIEDLHRGSNLPSPV-GNSVSRSGRHSALRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLSM-----ASDMAVG------QIMGAA STGPLPPPPPALP-------------------PSSDTPEA---------------------------------------- -----VQNGPATP-MPPPPPPPPPPPPPPPPPPPPPLPGPAADTVPAPPLPPPPPPSAPPLPG-------------TSSP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFAESLQMLTPQLHSIIAAS-VSIKSSQKLKKILEASEIILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TLLKEFIFNNEGKLKKLQDDAKIAQ-------DAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDPKSPSHKSKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITVLK-TVPFTARTAKRGS--RFFCEPVLTEEYHY---- >Monodelphis_domestica-FMNL2(ENSMODP_5... -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESLE NNVENSVDKSKPWSRSIEDLHRGSNLPSPV-GNSISRSGRHSTLRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVASMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMAKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDISILPV-VASGTLPA-----GTEATVNPNAFVGQVPGTP SSVPSPPPPPPLP-------------------PSTAASETGKRP------------------------------------ -----VQNGPVTSPVPPPPPPP------PPPPPPPPLPGPATDTPPAP-LPPPPPPSAPPLPG-------------TASP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLTSSKQKITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTADEICK-AIHIFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFSESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVREKYHQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGMDLTKREYTM---HDHN TMLKDFIHNNEGKLKKLQDDAKIAQ-------DAFDDAVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDPKSPSHKTKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITALKKNNITKFPNVHSRILETSHTDEPMR--------- >Ornithorhynchus_anatinus-FMNL2(ENSOAN... -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFGF----------------RAHE STVHRGGSKARSSSCSFPPRSRSSIVKVPP-GSFVSRRFLHSSIQYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNPRIDRTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFKN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLSLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMSKIVELEKQLMQRNKDLDVAR----------EIYKD-----------------------ANTQVHTLRK LIKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDISILPV-VVSGALPT-----GSEASVNS--CSGQVSGEA SSTSSPPPPPPLP-------------------PSTPTSEAEQNG------------------------------------ -----STTTVTGWRRRPSWAPEPHPGLNPPAVEPRSFPGSIPPVRKCHFPGLLPPHHPTLCPG-------------PGNS N-------------------------FIPHVLVLA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLTSSKQKITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTADEICK-AIHVVTDVSLRNDLLFPCPMRGKGTKNQIQVYRLPFR--RYFPEDLSRRQIRMSFRC PLQRKEGRTAVWATCHVRSNTCLSLGPQLHAVIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVREKYQQVALFYNELHYVEKAAAASVSLENVLLDVKELQRGMDLTKREYTM---HDHN TMLKEFIHNSEGKLKKLQDDAKIAQ-------DAFDDAVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLLEQEALMEQ-------QDQKSPSHKTKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-SQPYRRADAVRRSVRRRFDDQNLRPVNGAEITM >Gallus_gallus-FMNL2(ENSGALP_20433) -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESLE NNVENSMDKSKPWSRSIEDLHRGSNLPSPV-GNSASRSGRHSTLRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMAKIVELEKQLMQRNKELDVIR----------EIYKD-----------------------ANSQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDISILPVALASGMVPA-----GAEAAAGT--CVTPAAGVA SSVPLPPPPPPLP-------------------ALAAASEA---------------------------------------- -----VQNGPVTVPVPPPPPPPPP----PPPPPAPPLPGPALDTAPAAPLPPPPPPSAPPLPG-------------TASP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLTSSKQKITQKGSNK-------VTLLDA NRAKNLAITLRKAGKTADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPIENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLETKSTDRKQTLLHYISNVVKEKYQHVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGLDLTKREYTM---HDHN TMLKEFIQNNEGKLKKLQDDAKIAQ-------DAFDDAVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLMEQEAMMEQ-------QDQKSPSHKTKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITDLR-NQPYRRADALRRSVRRRFDDQTLRSANGTEITM >Taeniopygia_guttata-FMNL2(ENSTGUP_12478) -------------------------------------------------------------------------------- -------------AMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDF----------------ESLE NSVESSMDKSKPWSRSIEDLHRGSNLPSPV-GNSISRSGRHSTLRYNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---SSETLVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENLSHLS EKLQDTENEAMAKIVELEKQLMQRNKELDVIR----------EIYKD-----------------------ANSQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDISILP---------------------------------P STLALP-------------------------------------------------------------------------- ------------LPVPPPPPPPPP----PPPPPPPPLP-----DAAPAPLPPPPPPSAPPLPG-------------TS-P T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAMDLTSSKQKIPQKGSNK-------VTLLDA NRAKNLAITLRKAGKTADEICK-AIHVFDLKTLPVD-FVECLMRFLPTENEVKVLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFAESIQMLTPPLPSSLRNSPAPSQLPQEFSSPFP---APSGILQPLPSSS-GILQPFLS-HSS PHLLETKSTDRKQTLLHYISNVVKEKYQHVALFYNELHYVEKAAA--VSLENVLLDVKELQRGLELTKREYTM---HDHN TMLKDFIQSNEGKLKKLQDDAKIAQ-------DAFDDAVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENELRKKQEQALMEKLMEQEAVMEQ-------QDQKSPSHKSKWQQQELIAELR--RRQVKDNRHVYE--GKDGTIEDI ITALK-SVPFTARTAKRGS--RFFCDPSHHDESSC---- >Anolis_carolinensis-FMNL2(ENSACAP_12638) -------------------------------------------------------------------------------- ------------NAMNLPPDKARLLRQYDSEKKWELICDQ-ERFQ--VKNPPHTYIQKLKGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLNVLVEYLSFAQYAVTFDF----------------ESLE NNMENSMDKSKPWSRSIEDLHRGSNLPSPV-GSSISRSSRHSTLRYNTLPSRR--ALKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDHFKE-- ------------------------------------------VCGEKQRFEKLMEHFRN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLDEYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLS EKLQDTENEAMAKIVELEKQLMQRNKELDVVR----------EIYKD-----------------------ANTQVHTLRK MVKEK----EEAIQRQSTLEKKIHELEKQGSIKIQKKGDGDINILPVGVASGTLSS-----GSDAVTTT--VGGSVSGTT SSVALPPPPPPLP-------------------LSAEESEA---------------------------------------- -----VQNGPITTSMPPPPPPPPPP---PPPPPAPPLPGPAAEPVPAPPLPPPPPPSAPPLPG-------------TASP T-------------------------VVFNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQ-ITQKGSNK-------VTLLEA NRAKNLAITLRKAGKTSDEICK-AIQAFDLKTLPVD-FVECLMRFLPMENEVKMLRLYERE-RKPLENLSDEDRFMMQFS KIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKQTLLHYISNVVRDKYQQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGLDLTKREYTM---HDHN TMLKEFIQINEGKLKKLQDDAKIAQ-------DAFDDAVKYFGENPKTTPPSVFFPVFVRFVKAYKQ----AEE------ -ENDLRKKQEQALMEKLLEQEALMEQ-------QDQKSPSHKTKRQQQELIAELR--RRQVKDNRHVYE--GKDGAIEDI ITVLK-TVPFTARTAKRGS--RFFCEPVLTEEFHY---- >Danio_rerio-FMNL2(ENSDARP_24319) ------------------------------------------------------MGNAGSMNQHTDPRGHHMPLKLPMPE PAELEERFALVLNSMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYIHKLQSYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTYDG----------------DSSE NSTENSVDKSKAWSRSIEDLHGGNHLSSGGSGSNISRTNRHSTIRSNTLPSRR--TLKN------------SRLVCKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDHFKE-- ------------------------------------------VCLEEQRFEKLMEYFKN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYDFTKLGLDEYLDK---LKHTESDKLHVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLT EKLQDTENEAMAKIVELEKQLMQRNKELDSLR----------DVYKD-----------------------ANSQVHTLRR MVKEK----DEAIQRQCNLEKKIHELEKQGTIKIQKKGDGDIAILTSPPQGNGHLTGSESITGVPSGGVVSHGGVANGVA HGVHIPDPSLPLP-------------------PPSSSVS----------------------------------------- -----------ETVLNGPSAAPAPAPPPPPPPPPPPLP-----VDISAPMPPPPPPMAPPLPG-------------CGSP T-------------------------VIMNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKAQGPAIDITSSKQKTAQKGPHK-------ISLLDA NRSKNLAITLRKVGKTSEEICR-GIQLFDLRTLPVD-FVECLMRFIPSEAELKVLRQYEKE-RKPLENLTDEDRFMIQFS KIERLMQKMTIMAFVGNFTESIQMLTPQLHAVIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKITLLHYIANVVKDKYQQVSLFYNELNYVEKAAA--VSLENVLLDVKELQRGMDLTRKEYSM---HGHN TLLKDFIQQNENKLKKLQDDAKIAQ-------DAFDEVVKFFGENAKTTPPSVFFPVFVRFVKAYRQ----AEE------ -DNEQKKRHEQMMMEKLIEQEAMEQ--------EDQKSPSHKNKRQQQELIAELR--KKQVKDSRHVYE--GKDGAIEDI ITVLK-TVPFTARTAKRSS--RYFNEELHF--------- >Takifugu_rubripes-FMNL2(ENSTRUP_20770) --------------------------------------------------RRGNMGNAGSMEQHPDFRGHNMPLKLPMPD PGELEERFASVLNSMNLPPDKARLLRQYDNEKKWELICDQQERFQ--VKNPPHTYLQKLRGYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEDNKGLDVLVEYLSFAQYAVTFDG----------------DCLE NNPEATLDKSKPWSRSIEDLHGGSTLPSPITGNGLTRAGRHSTLRCNTLPSRR--TLKN------------SRLVCKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKSP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCMETQRFEKLMEYFKN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQFDFTKLGLDDYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENLSHMT EKLQDMENEAMSKIVELEKQLMQKNKDLESIR----------EVYKD-----------------------TSSQVISLRQ MVKEK----DEAIQRQTKLEKKIHELEKQGTIKIHKKGDGDISIL--PSLPVGTIA-----GAMMAANGSAVGPNHTGVA AGMPAPPPPPPPP-------------------PLPVNGTL---------------------------------------- ------ANGPSSPSPAAPPPPPPPPPPPPPPPPPPGLA-----SEISVPLPPPPPPLAPPLPG-------------CGTP T-------------------------VIMNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKAQGPTIDLNTSKTKVSQKMPNK-------VTLLDS NRAKNLAITLRKVGKTPEEICR-AIQIFDLRTLPVD-FVECLMRFQPTENEVKTLRQFEKE-RKPLESLTDEDRFMMQFS KIERLMQKMTIMAFIGNFCESVQMLTPQLHAVIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKLTLLHYIANVVKEKYAQVSLFYNELHYVEKAAA--VSLENVLMDVRELNRGMELTKREYSM---HGHN TMLKEFIAHNESKLKKLQDDAKIAQ-------DAFDEAVKFFGENAKTTPPSVFFPVFVRFVRAYRQ----AEE------ -DNEQRKRQAQILMEKLLEQEAMLE--------ENQKSPSHKNKRQQQELIQELR--KKQVKDSRHVYE--GKDGAIEDI ITDLR-NQPYRRADAVRRSVRRRFDDQNLRPMNNGEVVM >Tetraodon_nigroviridis-FMNL2(ENSTNIP_... -------------------------------------------------------------------------------- ------------NSMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHTYLQKLRGYLDPAVTRKVFLIFINV-- RKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEDNKGLDVLVDYLSFAQYAVTLDG----------------DCVE NNPEAALDKSKPWSRSIEDLHGGSTLPPPIAGTGLTRVGRHSTLRCNTLPSRR--TLKN------------SRLVSKKDD VHVCIMCLRAIMNYQ---YGFNMVMSHPHAVNEIALSLNNKSP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCMETQRFEKLMEYFKN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQFDFTKLGLDDYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENLSHMT EKLQDMENEAMSKIVELEKQLMQKNKDLESIR----------EVYKD-----------------------TSSQVISLRQ MVKEK----DEAIQRQTKLEKKIHELEKQGTIKIHKKGDGDISIL--PSSPVG--------TAVPAGNGAAVGPIHSGVA GGMPAPPPPPPPP-------------------PLPVNG------------------------------------------ ---------ACSRPEGRPLSAFSAVSNGPSTPSPAAAA-----SEISAPLPPPPPPLAPPLPG-------------CGTP TEPDPSAPQR---------------PVSLSQGVVTGSDATDTADG-----------------------PPVKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKAQGPTIDLSTSKQKMSQKVPNK-------VTLLDS NRAKNLAITLRKVGKTPEEICR-AIQIFDLRTLPVD-FVECLMRFQPTENEVKTLRQFEKE-RKPLESLTDEDRFMMQFS KIERLMQKMTIMAFIGNFCESVQMLTPQLHAVIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKLTLLHYIANVVKEKYAQVSLFYNELHYVEKAAA--VSLENVLLDVKELNRGMELTKREYSM---HGHN TMLKEFIGHNESKLKKLQDDAKIAQ-------DAFDEVVKFFGENAKTTPPSVFFPVFVRFVKAYRQ----AEE------ -DNEQRKRQEQILMEKLLEQEAMLE--------EDQKSPSHKNKRQQQELIQELK--KKQVKDSRHVYE--GKDGAIEDI ITVLK-TVPFTARTAKRGS--RFFCEPALNEEYHC---- >Gasterosteus_aculeatus-FMNL2(ENSGACP_... -----------------------------------------------------NMGNAGSMDQHADFRGHNMPLKLPMPE PGELEERFATVLSSMNLPPDKARLLRQYDNEKKWELICDQ-ERFQ--VKNPPHAYLQKLRSYLDPAVTR----------- KKFRRRVQEST--QVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDG----------------ESAE NDPEAVMDKSKPWSRSIEDLHGGGTLPSSITGNSITRAGRHSTIRNNTLPSRR--TLKN------------SRLVCKKDD VHVCIMCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKSP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCLETQRFERLMEYFKN-EDNNIDFMVACMQFINIVVH SVEDMNFRVHLQYDFTKLCLDDYLDK---LKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHMT EKLQDTENEAMSKIVELEKQLMQRNKDLESIR----------EVYKD-----------------------TSSQVHTLRQ VLKEK----DEAIQRQSNLEKKIHELEKQGTIKIHKKGDGDISILTSPSCGVGGLP-----GALTGGNVAAVTPNHVGVA ADT--PPPPPPAP-------------------PLPVNG------------------------------------------ ---------------------------------TPGLT-----SHLSAHLP----PVAPPLPG-------------CGTP T-------------------------VIMNSGLAA-----------------------------------VKIKKPIKTK FRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKAQGPAIDLISSKQKVIQKMPNK-------VTLLDS NRAKNMAITLRKVGKTPEEISK-AIQIFDLRTLPVD-FVECLMRFQPTENEIKVMRQFEKE-RKPLESLTDEDRFMMQFS KIERLMQKMTIMAFIGNFSESVQMLTPQIHAVIAAS-VSIKSSQKLKKILE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHYIANVVKEKYSQVSLFYNELHYVEKAAA--VSLENVLLDVKELQRGMELTKREYSM---HGHN TMLKDFIAHNESKLKKLQDDAKIAQ-------DAFDEAVKFFGENSKTTPPSVFFPVFVRFVKAYRQ----AEE------ -DNEHKKRQEQFLMENSLEQEAHDGGG------PEAQSPSHKNKRQQQELIQELR--KKQVKDSRHVYE--GKDGAIEDI ITDLR-NQPYRRADGVRRSVRRRFDDQNLRPMASGEVVV >Homo_sapiens-FMNL3(ENSP_293590) --------------------------------------------------MGNLESAEGVPGEPPSVPLLLPPGKMPMPE PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EGLE SGDDGAFDKLRSWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESIK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPNVRGLES-----VDSEALAR---------------------------VGPAELS EGM--PPSDLDLL-------------------APAPPPE----------------------------------------- ----------EVLPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLEELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- SVLRNFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Pongo_pygmaeus-FMNL3(ENSPPYP_5128) ---------------------------------------------GGPAAMGNLESAEGGPGEPPSVPLLLPPGKMPMPE PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EGLE SGDDGAFDKLRSWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESIK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPNVRGLES-----VDSEALAR---------------------------VGPAELS EGM--PPSDLDLL-------------------APAPPPE----------------------------------------- ----------EVLPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AGP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLEELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- SVLRNFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITGLH-CQPMVVRHQARSA--APPSGPPRAPGPH----- >Mus_musculus-FMNL3(ENSMUSP_85566) --------------------------------------------------MGNLESTDGGPGEPPSVPLLLPPGKTPMPE PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPNVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EGLE SGDDGAFDKLRSWSRSIEDLQPPNALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESIK----------ETYEN-----------------------TSNQVHTLRR LIKEK----EEAFQRR-----CHLEPSARGLES-----MGGEALAR---------------------------VGPTELT EGI--PPSDLDLL-------------------APAPPTE----------------------------------------- ----------ETLPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLEELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- SVLRNFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Oryctolagus_cuniculus-FMNL3(ENSOCUP_1... -------------------------------------------------------------------------------- --------SLLQSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDDNKGLDVLVDYLSFAQCSVMFDF----------------EGLE SADDGAFDKLRAWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNA---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESIK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPSARGLDS-----MGSEALGR---------------------------VGPAELS EGS--PASELDPL-------------------APAPPSEG---------------------------------------- ----------NQDPWEPGGAASLWGPRPH---------------------SPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKVLEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AVHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLEELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSL---HDN- SVLRSFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQ-KEHRPVYE--GKDGAIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Bos_taurus-FMNL3(ENSBTAP_22075) --------------------------------------------------MGNLESAEGGPGEPSSVSLLPPPGKMPMPE PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EALE SGDDGAFDKLRSWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESVK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPSARGLES-----MGSEALAR---------------------------VGSAELN EGM--PHSDLDLL-------------------TLAPPAE----------------------------------------- ----------EALPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLEELTAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- SVLRNFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKV----SRREVFKEA SASEKSEKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Canis_familiaris-FMNL3(ENSCAFP_12461) --------------------------------------------------MGNLESAEGGPGEPPSVSLLPPPGKMPMPE PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EGLE SGDDGAFDKLRSWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESVK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPGARGLES-----VGSEALAR---------------------------IGPAELS EGM--LPSDLDLL-------------------APAPPPE----------------------------------------- ----------EALPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKSKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLDELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- TVLRNFLSTNEGKLDKLQRDAKTAE-------EAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Equus_caballus-FMNL3(ENSECAP_5101) -------------------------------------------------------------------------------- ------------SSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLQSFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDF----------------EGLE SGDDGAFDKLRSWSRSIEDLQPPSALSAPF-TNSLARSARQSVLRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLT EKLLDLENENMMRVAELEKQLLQREKELESIK----------ETYEN-----------------------TSHQVHTLRR LIKEK----EEAFQRR-----CHLEPSARGLES-----VGSEALAR---------------------------VGPVELS EGM--PPSDLDLL-------------------APAPPPE----------------------------------------- ----------EALPLPPPPAPPLPPPPPP---------------------LPDKCPPAPPLPG--------------AAP S-------------------------VVLTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLEA NRAKNLAITLRKAGRSAEEICR-AIHMFDLQTLPVD-FVECLMRFLPTEAEVKLLRQYERE-RQPLDELAAEDRFMLLFS KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS-ASVKSSQKLKQMLE---IILALGNYMNSSKRGAVYGFKL-QSL DLLLDTKSTDRKMTLLHFIALTVKEKYPDLATFWHELHFVEKAAA--VSLENVLLDVKELGRGMELIRRECSI---HDN- SVLRNFLSTNEGKLDKLQRDAKTAEASTGWRREAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKE----AEQ------ -ENEARKKQEEVMREKQLAQEAKKLD---------AKTPSQRNKWQQQELIAELR--RRQAKEHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDAAHHDESNC---- >Ornithorhynchus_anatinus-FMNL3(ENSOAN... -----------------------------------------------------RAGSSPGPAPARPRDLSPQMGARPLPW APALEKRRRIGLSSMNLPPDKARLLRQYDNDKKWDLICDQ-ERFQ--VKNPPHTYIQKLRTFLDPSVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGLAPKILNNNNRGRDTLFIYL?FIHYRTKFDA----------------EGLE IGDDGPFEKLRAWSRSIEDLQHPSPLAAPF-ANSLARSARQSALRYSTLPGRR--ALKN------------SRLVSQKDD VHVCILCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCKELHRFEKLMDYFRN-EDSSIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQ------HTESEKLQVQIQAYLDNVFDVGGLLEDAETKSVALEKVEELEEHVSHLS EKLLDLENENMMRVAELEKQLLQREKELESIK----------ESLSLWTPAHRPEDHSR--VRAEGPSRFPARGGIASSE LELDPGTTPDSSLANHT--VGRALVPEATGLPSRPLPLAPSLPGGRG--------------------------DGPAGQA GGSRRPSPVPSLR-------------------QPRPSPAG---------------------------------------- ----------DVRECQPPSAHPAEAHQGERG------------------GLPAPVPPGHPPPGTGGEGPVPAD-PDLLSP A-------------------------LPPEVWAGGPRPR----GG-----------------------PAIRIKKPIKTK FRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLVCSKSKTSQKAASK-------VTLLEA NRAKNLAITLR-------NICR-AIHTFDLQTLPVD-FVECLMRFLPTEAEVKSLRQYERE-RQPLDELANEDRFMLLFS KVDRLTQRMAGMAFLGNFQDNLQMLTP----------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------- >Taeniopygia_guttata-FMNL3(ENSTGUP_15139) -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------YGTLPSRR--ALKN------------SRLVSQKDD VHLCIMCLRAIMNYQ---YGFNLVMSHPHAVNEIALSLNNKNP---RMKALVLELLAAVCLVRGGHEIILAAFDNFKE-- ------------------------------------------VCKEKHRFERLMEYFRN-EDSSIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLEEFLQK---SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHLT EKLLDLENENMMRVAELEKQLLQREKELEVVK----------VCWG-------------------------AVGAVGSGE IIKEK----DEGLQ-----------EENKGSEPDQLPRAPKHNLRHQ--------------------------KEPSEEP -----SIPVLPTV-------------------EVEPHPP----------------------------------------- ---------------NPPTPLPPPATP-----------------------LPGKCPPAPPLPG--------------ASP S-------------------------IALTVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPSQISGTVFSELDDERVLEDLDLERFEELFKTKAQGPALDLVCAKSKAAQKVATK-------VTLLEA NRAKNLAITLRKAGRSADEICR-AIHTFDLATLPVD-FVECLMRFLPTEAEAKALRQYERE-RKPLEELADEDRFMLQFS KVERLPQRMAIMAFLGNFAENIQMLTPQLNA------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------- >Danio_rerio-FMNL3(ENSDARP_99869) -------------------------------------------------------------------------------- ---LMHKCCVLQNSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLRGYLDPKVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLSFAQCAVMLDF----------------EGLE NGEDFSLDKAKSWSRSIEDLHQNG-------CNTLVRSARQSVLRYGSTSNSK--TIKN------------SRLVSQKDD VHVCIMCLRAIMNYQ---YGFNLVMSHAHAVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCKEKHRFEKLMEYFRS-EDGNIDFMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLDDFLEK---SKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHVT EKLLDVENETMTKVADLEKQLLHKDKELAVIK----------ETYES-----------------------ASTQVHTLRR MIQEK----DAAFQRHNNIEKQLLELEQQGTIRLRKQPDGDIAIETL--------------------------G------ -AGAVAGTPLTDL-------------------ELLSERQK---------------------------------------- ----------EKPPLLWKTLPSVESIP----------------------IPPPPP---PPLPG--------------PSP S-------------------------VILSVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQINGTVFNEIDDDRVLEELDLEKFEELFKTKAQGPVVDLSCSKSKVSQKVINK-------VQLLDA NRSKNLAITLRKANKTTEEICK-AIQTFDLKALPVD-FVECLMRFLPTEAESKLLRQYERE-RRPLDQLAEEDRFMLLFS KIERLTQRMSIITFVGNFNDNVNMLTPQLNAIIAAS-ASVKSSPKLKKILE---IILALGNYMNSSKRGSVYGFKL-QSL DLLLDTKSTDRKMTLLHYIALVVKEKYPELANFYNELHFVDKAAA--VSLENVLLDVKELGKGMDLVRRECSL---HDH- AVLKGFAQTSDTQLDKLAKDAKTAE-------EAFNNVVLYFGESPKTTPPSVFFPVFVRFIRAYKE----AVE------ -ENEQRKKQEEAMREKLLAQEAKQHD---------PKVQAQKKRHQQQELIAELR--RRQAKDHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCDANLFDESIC---- >Takifugu_rubripes-FMNL3(ENSTRUP_22683) -----------------------------------FPRPWAGLLLKPRPSLKLKMGNIESVDGQSEMKHHIMPLKVPMPD PTELEEKFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLRGYLDPRVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLSFAQCAVMFGF----------------EGSE NGEEDFLDKSKSWSRSIEDLHRPTSQ--PF-YNTLVRSARQSVLRYGSVSSSR--TIKN------------SRLVSQKDD VHVCIMCLRAIMNYQ---YGFNMVMSHAHAVNEIALSLNNKNS---RTKALVLELLAAVCLVRGGHEIILSAFDNFKE-- ------------------------------------------VCKEKHRFERLMDYFRS-EEGNIDFMVACMQFINIVVH SVEDMNFRVHLQFEFTKLGLDDYLEK---SKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNAALEKVEELEDHLSHVT EKLLEVENETMMKVADLEKLLLHKDKELQVIR----------ETYES-----------------------TSSQVNTLRK VIKEK----DAAFQRHFNIERRLLELEQQGTIRLHKKPDGDIAIEPC--------------------------VVGGS-S NGGVILQGEIGQL-------------------SLGSTVGL---------------------------------------- ----------TVPGGPDTSLPPASEAPPPPPPPPPPPPPLPSASSPNIPAPPPPPPLAPPLPD--------------ASP S-------------------------VILSVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQINGTVFNEIDDERVLEELELERFEELFKTRAQGPIMDLSCTKSKVAQKAVNK-------VTILDA NRSKNLAITLRKANKTSEEICK-AIEKFDLKTLPVD-FVECLMRFLPTEMEVKALRQYERE-RRPLDQLAEEDRFMLLFS KIERLTQRMNIITFIGNFSDNVAMLTPQLNAIIAAS-ASVKSSPKLKRMLE---IILALGNYMNSSKRGCVYGFKL-QSL DLLLDTKSTDRKMTLLHYIALIVKEKYPELANFYNELHFVDKAAAE-VSLENVLLDVRELGKGMDLIRRECSL---HDH- SVLKGFLQASDTQLDKVQRDAKTAE-------EAFNNVVNYFGESAKTAPPSVFFPVFVRFLKAYKD----AVE------ -ENELRKKQEQAMREKLLAEEAKQQD---------PKVQAQKKRQQQHELIAELR--KRQAKDHRPVYE--GKDGTIEDI ITDLR-NQPFLRADALMRS--GWKR-------------- >Tetraodon_nigroviridis-FMNL3(ENSTNIP_... -------------------------------------------------------------------------------- --------------MNLPPDKARLLRQYDNEKKWDLICDQ-AFLSGATAAYPGQSCGAIFGAFYPNIVA----------- RLIEPRTED---------------------VREFLNDENRGLDILVEYLSFAQCAVMFDF----------------EGLE NGEEDFLDKSKSWSRSIEDLHRPSSQ--PF-YNTLVRSARQSVLRYGSVSSSR--TIKN------------SRLVSQKDD VHVCIMCLRAIMNYQV-PYGFNMVMSHAHAVNEIALSMNNKNS---RTKALVLELLAAVCLVRGGHEIILSAFDNFKESS KHRNETSTVHTKKGTSQTELINPVVKTASYFRTSCN----ETVCKEKHRFERLMDYFRC-EEGNIDFMVACMQFINIVVH SVEDMNFRVHLQFEFTKL-LDDYLEK---CKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNAALEKVEELEDHLSHVT EKLLEVENETMMKVADLEKLLLHKDKELQIIRVRRQLLNARRETYES-----------------------TSSQVTTLRR VIKEK----DAAFQRHFNIERRLLELEQQGTIRLHKKPDGDIAIEPC--------------------------VGGGGGS GGGIILQSEIGQL-------------------ALGSTAGL---------------------------------------- ----------TELGGPDTSLPPASEAPPPPPPPPPPPPPLPSALSPNIPAPPPPPPLAPPLPD--------------ASP S-------------------------VILST--------------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQINGTVFNEIDDER---ELDLEKFEELFKTRAQGPIVDLSCTKSKVAQKAVNK-------VTILDA NRSKNLAITLRKANKT-----------FDLKALPVD-FVECLTRFLPTETEVKALRQYERE-RRPLDQLAEEDRFMLLFS KIERLTQRMNIITFIGNFSDNVAMLTPQLNAIIAAS-ASVKSSPKLKRMLE---IILALGNYMNSSKRGCVYGFKL-QSL DLLLDTKSTDRKMTLLHYIALIVKEKYPELANFYNELHFVDKAAAE-VSLENVLLDVRELGKGMELIRRECSL---HDH- LVLKGFLQASDAQLDKLQRDAKTAE-------EAFNNVVNYFGESAKTTPPSVFFPVFVRFLKAYKD----AVE------ -ENELRKKQEQAMREKLLAEEAKQQD---------PKVQAQKKRQQQQELIAELR--KRQAKDHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCEANLCDDANC---- >Gasterosteus_aculeatus-FMNL3(ENSGACP_... ------------------------------------------------------MGNIESVDGQSDMKHHIMPLKVPMPD PTELEEKFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQ-ERFQ--VKNPPHTYIQKLRGYLDPGVTR----------- KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENRGLDVLVEYLSFAQCAVMLNF----------------EGLE NGEDGFLDKAKSWSRSIEDLHHSSSQ--PF-CNTLVRSARQSVLRYGTVSNSK--TIKN------------SRLVSQKDD VHVCIMCLRAIMNYQ---YGFNMVMSHAHAVNEIALSLNNKNS---RTKALVLELLAAVCLVRGGHEIILSAFDHFKE-- ------------------------------------------VCKEKHRFERLMDYFRS-EEGNIDYMVACMQFINIVVH SVEDMNFRVHLQYEFTKLGLDDYLEK---CKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNAALEKVDELEEHLSHVT EKLLEVENETMMKVADLEKVLLQKDKDLHAIR----------ETYES-----------------------TNTQVTTLRR VIKEK----DAAFQRHFNIERRLLELEQQGTIRLHKKADGDIAIEAL--------------------------GVGGG-- GLGIPLG-DISQL-------------------SLGSTAGF---------------------------------------- ----------NVPGGPDSSLPPASHCAP---------------------VPPPPPPLAPPLPG--------------ASP S-------------------------VILSVGLS-----------------------------------AIRIKKPIKTK FRLPVFNWTALKPNQINGTVFNEIDDERVLEELDLERFEELFKTRAQGPIVDICCTKSKVAQKTVNK-------VTLLDA NRSKNLAITLRKANKTTEEICK-AIEKFDLKALPVD-FVECLMRFLPTEGEVKVFRQYERE-RRPLDQLAEEDRFMLFFS KIERLTQRMNIITFVGNFSDNINMLTPQLNAVIAAS-ASVKSAPKLKRVLE---IILALGNYMNSSKRGCVYGFKL-QSL DLLLDTKSTDRKMTLLHYIALILKEKYPELANFYNELHFVDKAAA--VSLENVLLDVRELGKGMDLIRRECTL---HDH- SVLKGFVQASDTQLDKLQKDAKTAE-------EAFNNVVNYFGESAKTTPPSVFFPVFVRFIRAYKD----AVE------ -QNEQRKKQEEAMREKLLAEEAKQHD---------PKVQGQKKKQQQHELITELR--KRQAKDHRPVYE--GKDGTIEDI ITVLK-SVPFTARTAKRGS--RFFCEANLCDDANC---- >Homo_sapiens-FMNL1(ENSP_327442) ---------------------------------------MGNAAG--------SAEQPAGPAAPPPKQP--APPKQPMPA AGELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYVDTGGVSRKVAADWMSNL G-FKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVTYDM----------------ESTD NGASNS-EKNKPLEQSVEDLSKGPPSSVP--------KSRHLTIKLTPAHSRK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLT ERLRDAENESMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTAMGPSR RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVS----------------------------IEILPVAVA TPSGGD--APTP-------------------GVPTGSPSP---------------------------------------- -------DLAPAAEPAPGAAPPPPPP-----LPGLPSPQEAPPSA----PPQAPPLPGSPEPPPAPP-------LPGDLP PPP---------------------PPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGR-----RDSELGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKAAQKAPSK-------ATLIEA NRAKNLAITLRKGNLGAERICQ-AIEAYDLQALGLD-FLELLMRFLPTEYERSLITRFERE-QRPMEELSEEDRFMLCFS RIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAAS-MSIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLADVRSLQRGLELTQREFVR---QDDC MVLKEFLRANSPTMDKLLADSKTAQ-------EAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKK----AEQ------ -EVEQWKK-EAAAQEAGADTPGKGEP-------PAPKSPP-KARRPQMDLISELK--RRQQ-KEPLIYES-DRDGAIEDI ITDLR-NQPYIRADTGRRSARRRPPGPPLQVTSDLSL-- >Pongo_pygmaeus-FMNL1(ENSPPYP_9337) -----------------------------------------------------SAEQPSTPAQQE???P--APPKQPMPA AGELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYVDTGGVSRKVAADWMSNL G-FKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVTYDM----------------ESTD NGASNS-EKNKPLEQSVEDLSKGPPSSVP--------KSRHLTIKLTPAHSRK--TLRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNVFDVGALLEDTETKNAVLEHMEELQEQVALLT ERLRDAENESMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTAMGASR RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVS----------------------------IEILPVAVA TPSGGD--APTP-------------------GVPTGSPSP---------------------------------------- -------DLAPAAGPAPGAAPPPPPP-----LPGLPSPQEAPPSA----PPQAPPLPGSPEPPPAPP-------LPGDLP PPP---------------------PPPPPPPGTDGPVPPPPPPPPPP-GGPPDAL-R-----RDSELGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKA-------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------- >Mus_musculus-FMNL1(ENSMUSP_46296) ---------------------------------------MGNAAG--------SAEQPAGPTASPPKQP--AVPKQPMPA AGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYLDTGGVSRKVASDWMSNL G-FKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDM----------------ESTD SVASGA-EKSKPLDQSVEDLSKAPPSSVP--------KSR-LTIKLTPAHSRK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKSP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRH-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLT ERLRDTENDSMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTPMGTSR RIPEPEKVPVPTVVRPSALELKVEELEEKGLIRILRGPGDVVS----------------------------IEILPGAAA TPSGDD--AQAP-------------------RVSTDSPSTA--------------------------------------- ------ESIPEAASP-PPPPPPPPPP-----LPNLQSQQEAPPSA----PPLAPPLPGCAEPPPAPP-------LPGDLP PPP---------------------PPPP--LGTDGPVPPPPPPPP---GGPPDILGG-----QGPDIGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDISALKGKASQKAPTK-------TILIEA NRAKNLAITLRKGNLGADRICQ-AIETYDLQTLSLD-FLELLTRFLPTDYERSLIARFEKE-QRPMEELSEEDRFMLRFS RIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAAS-MSIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLGDVRSLQRGLELTQREFVR---QDDC LVLKEFLRANSPTMDKLLADSKTAQ-------EAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKK----AEQ------ -EVEQWKK-EAAA-----DTSGREEP-------PTPKSPP-KARRQQMDLISELK--RKQQ-KEPLIYES-DRDGAIEDI ITDLR-NQPYIRADTGRRSARRRPPGPPLPVTTDLAL-- >Rattus_norvegicus-FMNL1(ENSRNOP_4353) ---------------------------------------MGNAAG--------SAEQPAGPTASPPKQP--AVPKQPMPA AGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYLDTGGVSRKVATDWMSNL G-FKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDM----------------ESTE NVASGT-EKNKPLEQSVEDLSKAPPSSVP--------KSR-LTIKLTPAHSRK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLT ERLRDTENDSMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTPMVTSR RIPEPEKVPAPTVVRPSALELKVEELEEKGLIRILRGPGDVVS----------------------------IEILPGAAA TPSGDD--APAP-------------------RVSTDSPSTA--------------------------------------- ------ESVPEAASPTPPPPPPPPPP-----LPNLQSQQEALPSA----PPLAPPLPGCAAPPPAPP-------LPGDLP PPP---------------------PPPP--LGTDGPVPPPPPPPP---GGPPDILGG-----QDPEIGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEQFKTKSQGPSLDISALKGKTAHKAPTK-------ATLIEA NRAKNLAITLRKGNLGADRICE-AIETYDLQTLSLD-FLELLTRFLPTDYERSLIARFEKE-QRPMEELSEEDRFMLRFS RIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAAS-ISIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLGDVRSLQRGLELTQREFVR---QDDC LVLKEFLRANSPTMDKLLADSKTAQ-------EAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKK----AEQ------ -EVEQWKK-EAAA-----DTSGREEP-------PAPKSPP-KARRQQMDLISELK--RKQL-KEPLIYES-DRDGAIEDI ITDLR-NQPYIRADTGRRSARRRPPGPPLPVTADLSL-- >Oryctolagus_cuniculus-FMNL1(ENSOCUP_1... ---------------------------------------RQEHQG--------WPGIPRNPGSLPVSLPPSRRPPRVLPY PVQTEPPLQLSLNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYLDTGGVSRK--------- --FRRRVQEST--QVLRELETSLRTNHIGWVQEFLNDENRGLDVLLEYLAFAQCSVAYDM----------------DSTD NGAPSP-EKSKPLEQSVEDLSKGPPSSVPK-SRLTIKTRNQAPKRLTPAHSRK--TVRN------------SRIVSQKAD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNVFDVGALLEDTETKNAVLEHMEELQEQVALRG S--RDAENESMR-SPNWEKQLSQARKELETLREP-----------------------------------AAD-------- --------PSPGNHR---LELKVEELEEKGLIRILRGPGDDVS----------------------------IEILPGAVA TPSVGDGDAATP-------------------GVPAGSPSP---------------------------------------- ------------GTDGPVPPPPPPPP--------------GDPLS----SSRAPALSG----------------LGVGVL RQG---------------------RGSSPLSGIS-----------------------------------GVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSEFEEQFKTKSQGPSLDLSALKGKAAQKAPSK-------ATLIEA NRAKNLAITLRKGNLGADRICQ-AIETYDLQALGLD-FLELLTRFLPTEYERSLIARFERE-QRPVEELSEEDRFMLRFS RIPRLPERMATLTFLGNFPDTAQLLMPQLNAIIAAS-MSIKSSEKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLGDVRALQRGLELTQREFVR---QDDC VVLKEFLRTNSPTMDKLLADSKTAQ-------EAYESVVEYFGENPKTTAPSTFFSLFSRFTKAYKK----AEQ------ -EVEQWKK-EAAAQEAGADPQGSGQP-------PAPKSPP-KARRQQMDLISELK--RKQQ-KEPLIYES-DRDGAIEDI ITVLK-TVPFT-ARTGKRTSRLLCEASLGEEMPL----- >Bos_taurus-FMNL1(ENSBTAP_34709) -------------------------------------------------------------------------------- ------------NCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLKSYLETGGVSRK--------- --FKRRVQEST--QVLRELEISLRTNHIGWVQEFLNEENRGLDVLLDYLAFAQCSVAYNM----------------ETTD NGAPGS-EKSKPLEQSVEDLSKGPPSSLPP-P----PKSRHLTIKLTPAHSKK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILSAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLT ERLRDAENESMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTLMGTSR RPSEPEKVPAPVPARPSALELKVEELEEKGLIRILRGPGDAVS----------------------------IEILPVAVA TPSGSD--APTP-------------------GAPTGSPS----------------------------------------- ----------------PAPPPPPLPP-----LPGLPSQQEAPPLA----PPLAPPLPGSPEPPPPPP-------LPGDQP PPP---------------------PPPPPPPGADGQVPPPPPPPP---GGPTDAQAG-----PDSEMGPGVKAKKPIQTK FRMPLLNWVALKPNQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSVDLSALKSKAAQKAPSK-------ATLIEA NRAKNLAITLRKGNLGADRICQ-AIETYDLQTLGLD-FLELLTRFLPTEYERSLITRFERE-QRPIEELSEEDRFMLRFS RIPRLPERMNTLTFLGNFPDTAQMLMPQLNAIIAAS-MSIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLGDVRSLQRGLELTQREFVR---QDDC VVLKEFLRVNSPVMDKLLADSKTAQ-------EAYESVVEYFGENPKTTSPSMFFSLFSRFIKAYKK----AEQ------ -EVEQWKK-EAAAQEAGTDTAGKGEP-------QAPKSPP-KVRRQQMDLISELK--RKQQ-KEPLIYEG-DRDGAIEDI ITDLR-NQPYIRADTGRRSARRRPPGPPLQVTSDLSL-- >Canis_familiaris-FMNL1(ENSCAFP_20371) ---------------------------------------MGNAAG--------SAEQPAGPAAPSPKQP--AAPKQPMPA AGELEERFNRVLNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLRSYVETGGVSRKVAADWMSNL G-FKRRVQEST--QVLRELEISLRTNHIGWVEEFLNEENRGLDVLLEYLAFAQCSVTYDM----------------ESTD NGVPGS-EKSKPLEQSVEDLSKGPPSSLPP-Q----PKSRHLTIKLTPAHSRK--TLRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMTHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEQHRFEKLMEYFQK-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLER---LRLTESDKLLVQIQAYLDNVFDVGALLEDTETKNAVLEHMEELQEQVALLT EKLRDAENESMAKIAELEKQLSQARKELETLRER-----------------------------------FSESTPMGASR RPPEPEKVPTSVPARPSALELKVEELEEKGLIRILRGPGDAVS----------------------------IEILPVAVA TPSGND--ALTPP------------------GVPTSGPSA---------------------------------------- -------EPAPGAAPPPPPPPPPPPP-----LPSSSSQQEAPPSA----PPLASPIPGSSDPPPPPPP------LPGGLP PPP---------------------PPPPLPPGADGPVPPPPPPPP---GGPSDAPGG-----SGPEMGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKGKAAQKAPSK-------ATLIEA NRAKNLAITLRKGNLGADRICQ-AIEMYDLQALGLD-FLELLTRFLPTEYERSLITRFEQE-QRPMEELSEEDRFMLRFS RIPRLPERMATLTFLGNFPETVQLLMPQLNAIIAAS-MSIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DVLLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGS--VSLDSVLGDVRSLQRGLELTQREFVR---QDDC MVLKEFLRANSPTMDKLLADSKTAQ-------EAYESVVEYFGENPKTTSPSMFFSLFSRFIKAYKK----AEQ------ -EVEQWKK-EAVAQEAGADAPGKEEA-------PAPKSPP-KARRQQMDLISELK--RKQQ-KEPLIYES-DRDGAIEDI ITVLK-TVPFT-ARTGKRTSRLLCEASLGEEIPL----- >Equus_caballus-FMNL1(ENSECAP_20484) ----------------------------------------ATRAG--------SAEQPASLAALSPKQP--RRPSRRCPA G-ELKERFNRVLNCMNLPPDKVQLLSQYDNEKKWELICDQ-ERFQ--VKNPPAAYIQKLRSYLETGGVSRKVAADWMSNL G-FKRRVQEST--QVLRELEISLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVTYDI----------------ESTD NGAPGS-EKSKPLEQSVEDLSKGPPSALPP-Q----PKSRHLTIKLTPAHSRK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEIALSLNNKNP---RTKALVLELLAAVCLVRGGHEIILAAFDNFKEA- -------------------------------------------CGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTHLGLDLYLEK---LRHTESDKLQVQIQAYLDNVFDVGALLEDTETKNAVLEHMEELQEQVTLLT ERLRDAENESMAKIAELEKQLSQARKELETLRDR-----------------------------------FSESTAMGVSR RPPEPEKVPAPAPARPSALELKVEELEEKGLIRILR-PGDAVS----------------------------IEILQVAVA TPSGSD--APTP-------------------GVPTGSPSP---------------------------------------- -------DLPPAAEPVPGAAPPPPPPPSPPPLPSLPSQQEAPPLA----PPPAPPLPGSPEPPPPPP-------LPGDLP PPP---------------------PPPPPPPGTDGPVPPPPPP----LGGPSDALGR-----PGPEMGPGVKAKKPIQTK FRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKAVQKAPTQ-------ATLIEA NRAKNLAITLRKGNMGADRICQ-AIETYDLQALGLD-FLELLTRFLPTEYERSLIARFERE-QRPMEELSEEDRFMLRFS RIPRLQERMATLTFLGNFPDTAQLLMPQLNAVIAAS-MSIKSSDKLRQILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKASS--VSLDSVLGDVRSLQRGLELTQREFVR---QDDC VVLKEFLRANSPTMDKLLADSKTAQ-------EAYESVVEYFGENPKTTSPSMFFTLFSRFIKAYKK----AEQ------ -EVEQWKK-EAAAQEAGADTLGRGEP-------PAPKSPP-KIRRQQMDLISELK--RKQQ-KEPLIYES-DRDGAIEDI ITVLK-TVPFT-ARTGKRTSRLLCEASLGEEIPL----- >Xenopus_tropicalis-FMNL1(ENSXETP_7013) ---------------------------------------MGNAAGSLDMFQARDTRGQSTSGTPPQKQKEGTPSKLPRPN SVELEQRFNVVLNAMNLPPDKIQVLRQYDQDKKWELVCDQ-ERFQ--VKNPPAAYIQKLRSYLDTGGISRK--------- --FKRRVQEST--QVLRELEISLRTNHIGWVEEFLSPEVGGLDALVEYLSYAQGSFPIDT----------------ECSD NGTP---EKSKSLQRSLEDINKSSSSPSPT-N--TPSRSRNLTARYN-LHSRS--TMRN------------TKHANMKDD VHVCIMCLRAIMNY---QSGFSMVMSHSSCVNKITLSLSNKNP---RTKALVLELLAAVCLVRGGHELILSAFNYFMEM- -------------------------------------------CGEGARFEKLMEYFRT-EDSNIDFMVACMQFINIVVH SVKNMNFRVFLQYEFTLLGLDEYLEI---LKNTESERLQVQIQAYLDNIFDVNSLLEDTDTKNEMLEHVEDLQEHLTRVT EKLQLTENEYVRRVAELEKQLDQCRREMSSAKEK-----------------------------------LVVQAPQVTQN IVQRTELVKRSVLWVEPAGDTCTEDISDNTFTSDLPSAASTPPLSPS---------------------AIRITLISPSVT STGALSSRGNSPRSTTPPALLPSLPESSEIFSIPAPSPVPSS-------------------------------------- ------EDSSATALKASKVTPVPSLPTIIDQTQTSNAQSLSRTHDESPPPPPPPPLPSIAEPPPPPPLP-----MSADVP PPPPLPELSGIPPPPPLPMGEQGAPPPPPSMGAPGVPPPPPPPPSGFGPAPPPPPPGGQ---PAATLNTGVSIKKPIQTK LRMQVLNWVALKPTQINGTVFTHLNDEKVLQELDMSDFEENFKTKAQGPSQTTFSMKVKAAQNQPNK-------VSLIET NRAKNLAITLRKGGLSPEAITS-AIQKYDMQAFNMD-FLELLARFLPTDWERQQISRYCRD-QKPLDDLTAEDRFMVHLC SIPRLAERVNTMTFMANFPDMASRLKPQLDALIAAS-MSIKSSDKLKGILE---LVLAFGNYMNSSKRGAAYGFRL-QSL DVLLETKSTDRKQTLLHYMIRVICEKYSHLSNFYCDLNFMDKAAT--VSLDSVLADVKSLQAGMEQVQKEFTK---QDDC LILKDFIKSNMDSLKQMSADAKTAQ-------EAYDAAVGYFGENAKTTPPSTFFPIFVRFIKAYKQ----AEQ------ -DLETWKKQESAVQEAKPETAGK----------QAPQSPVVKSLRPQVNLMAELN--KKLQTKEPRVYE---QNWAIEDI ITDLR-NQPYRRTDVGRRSGKKQNSGQPLNTPDIQV--- >Anolis_carolinensis-FMNL1(ENSACAP_16216) -------------------------------------------------------------------------------- ------------NSMNLPPDKMKLLSQYDNEKKWELICDQ-ERFQ--VKNPPSAYIQKLKGYLDSGGFSGKAVIPILGRL ALFKRRVQEST--QVLRELEISLRTNYIGWVQEFLNEENKGLDVLVDYLAFAQCSVTYDM----------------DSTD NGSPGS-DKGRPLDRSMEDLSRNSSPTQGS-T-----KTRHFTVRLNTAHSRK--ALRN------------SRIVSQKDD VHVCIMCLRAIMNY---QSGFSLVMNHPACVNEITLSLNNKNP---RTKALVLELLAAVCLVRGGHDIILAAFDNFKEV- -------------------------------------------CGEKNRFEKLMEYFRN-EDSNIDFMVACMQFINIVVH SVENMNFRVFLQYEFTQLGLDEYLER---LRYTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHVEDLQEEVGQLT EKLQDAENESLARVAELEKQLCQSRRELEALRAR-----------------------------------TTSDEQ--GPP LLQKQSSQGAGEPPLPSALERKLEELEDKGLIRILRGAGSDAITG--------------------------IEIIPVIVD TTAATTITIEAPS------------------STSTDVPSP---------------------------------------- -------SASPVPPAAPEIPPAPPLP---LTQTTREEISLPPPPS----PPPAPPLPGGSEPPPAPPL------PIAATG SHP---------------------PPPPPLPSVNGPAPPPPPPPPMVEGGQPNNASGKSGLIRNKALFQTVKIKKPIQTK FRMPIFNWVALKPNQVNGTVFNELNDEKVLQELDMSHFEDQFKTRAQGPGREFGAVKVKVSQKASSK-------VTLIEC NRAKNLAITLRKGGLPIDGICK-AIQTYDLQSLSLD-FLELLMRFIPTEYELTTIRKYEKE-QRPLDDLSDEDQFMIKFS KIPRLTERMNIMTFLGNFGDTVQLLLPQLNAVIAAS-MSIKASTRLRQILE---IVLAFGNYLNSSKRGAAYGFRL-QSL DALLDMKSTDRKQTLLHYIVRVIEEKYPDLISFSSELHFLDKAAT--VSLDSVLQDVRGLQRGMELTRKEFMR---QDDS AVLKEFLKTNTEVMEKLQADSKTAQ-------EAYEATVEYFGENPKTTPPTMFFPMFVRFIKAYKKK--KAED------ -DIQLWKKQEAAAKEEEMDSSKKEEQ-------VAAKSPTHKAKRQQMDLIAELK--KKQMVKEPLIYE--EKDGAIEDI ITALK-TVPFT-ARTGKRSSRLFCDASFNEESPL----- >Danio_rerio-FMNL1(ENSDARP_77930) -----------------------------MGN-AAGGLEQAEGQE-----AKGSTGGLNPAPSILKKK--CAPPKLPMPP EEELEERFNVVLSTMNLPPDKMKLLSQYDNEKKWELVCDQ-ERFQ--VKNPPSAYLTKIKSFYQDQGGVTRR-------- --FKKRVQEST--QVLRELEISLRTNHIGWAQEFLNEENQGLDVLVDYLSYSQSDVPFEV----------------ESVE NGGSIS-DNRRMSERSVEDLAKNVNHSAP--HTMT-RAARALTVRITSLAHSR-KTLRI------------ARLATQRDD VHLCIMCLRAIMNY---QSGFNLVMTHPRCVNEITLSLNNKNP---RTKALVLELLAAVCLVRGGHDIIISAFDNFKDAS G--------------------------------------------EKNRFEKLMEYFMH-DDSNVDFMVACMQFINIVVH SVENMNFRVHLQYQFSQLGLDQYLES---LKDMESEKLQVQIQAYLDNVFDVGALLEDAENKGDIVDLVADLQENNAQLT ARLQECENGALDKIAELEQQLLQATKESALLKQE-----------------------------------RQSQPSQVDRE KGSEKE----------SKLEKKLKELQEKGLLRLERTVSGSLD----------------------------IDVIPVTLE KIVTQTGKSRRRS----------------KRSFPSGCHLKRMHEITLIYLMLLYKMTRIKKQNILHVVYTYIQSAQSTMC SQKHGVFLKKESCTSGEEKSMPAMTV------PDSASQAPPSPAAAPPPPPPPPPLPGAEVLEVEAPPP------GSGPP PPP----------------------GAPPAPGAETVFY------------------------------TGPKARKTIQTK FRMPLLNWQALKPNQVSGTVFSELNDEQVLQALNMDLFAEQFKTKAQGPPADLSKLKVKVAEKAPTK-------VSLLEA NKAKNLAITLRKGGMNPDKICT-AIESYDQ-SLSLD-FLELLERFIPSEYEMKLLQNYEKE-GRPLEDLSEEDRFISRFG KIPRLSQRINTLTFMGNFPESIKRLQPQLDAIIAAS-VSLKSSSKLKKMLE---IILAFGNYMNSSKRGAAYGFRL-QSL DLLLDTKSTDRTQTLLHFIANMVHEKYPELTSFHNELRFVDKAAL--VSLDGVLQDVRSLERGMEGTKKEFMV---QDDI PALKEFVKANSDVLDSLVKDGKTAQNK-----EAYAAVVEYYGENPKTTQPSMFFPIFARFIKAYKQ----AEQ------ -DNEQKKKQEMAAEEQATPSPKKKEG-------TPQKGP----MMPKMDLIAELK--KRQV--KPQVT-----DGAIDDI ITDLR-NSPYRRGDGRRAAPRQSDAQVVYSSSLEM---- >Danio_rerio-FMNL1(ENSDARP_102181) -------------------------------------------------------------------------------- ------------NSMNLPPDKVMLLSQYDSEKKWELVCDQ-ERFQ--VKNPPSAYIQKLK-SVLEQGGGRK--------- VQFKRRVQEST--QVLRELEISLRTNHIGWAEEFLNEENNGLDVLVDYLSFAQRAVIYDM----------------DSSS ENGSFE-EK------SVEDLTTSATNSPT--HNSP-RSARPFTTRSVTLSNLK--ALRY------------SRMLSQNNH LHLCIMCLRAIMNY---QLGFNQVTAHPSCVNEITLSLNN------RTKALVLELLAAVCLVRGGHEMILAAFNNFRE?- -------------------------------------------CGEKNRFEKLMEYFRN-EESNIDFMVACMQFINIVVH SVEDMNFRVFLQYEFTQLGLDSYLEK---LNMTESERLQIQIQAYLDNVFDVGAMLEDAEAKNTLMEHLEELQEQNTQLN TRLHQCEIEALEKTTDLEQQLIQSSKQVELLKQ-----------------------------------LQQVNVCLLFQE SVKEVRLSSSSFSSSSMQMEKMLQLLVERGLIRMERSASGALD----------------------------LHIIAAANT TVNCN------------------------EIISKCTGSWS---------------------------------------- ---------------KTSVHPLLCIF------FIHIINKSYQDKCSKETSPVPP----------------------LAPP TS-----------------------PFIGRTGTIKTGE------R----------------NHDSHLWYRMKGKQPIKTK YRMPLLNWQALMEEQVAGTVFTELDDQTVLQELNMDVFEELFKTKAQSAPVDVGTLKVKVAQKASSK-------ISLLEP NRAKN------------------EVETYNLELLKSD-FLELLERFVPSDYELKLIQNYERS-GRPLVELSEEDRFMMAFS KIPRLTQRISTLTFMGSFSESVLILKPQLNAVISAS-KSIRSSSKLKKILE---IILAFGNYMNSGKRGSAYGFRL-QSL DLLLDMKSTDRKQTLLHFIVSIIQDKYPQLSNFHTELHFLDK-AAL-VSLDSVLSDVCSLQKGMDVVCKELEQ---QQNS SVLTQFICTNRGLLDTLIKDSTTAQ-------EAYQSVVEYFGENPKSTPPSAFFPVFTRFIKAYKL----CEQ------ -EIDQRRKRLSDSEE-TADLKFSDAP-------VHRQKVK-PLRLPQLDLISELK--RRQM--SPLVRE--GKDGAIEDI IT------------------------------------- >Oryzias_latipes-FMNL1(ENSORLP_5641) -------------------------------------------------------------------------------- --------------MNLPPDKLKLLSQYDNDKKWELVCDQ-QHMT--LGR------LLLPSCGQSMGSIYSNN------- --LWVWVLLAE--QKR-------------WAQEFLNEENKGLDVLVEYLSHAQSDSPFDM----------------DSVE NG-TVS-DRKKSMDRSMEDLTKSPSSSQS--HGVT-RAARALTVRISSTLVN--KMQKK------------PHVSLQRDD IHVCIMCLRAIMNYQV-QSGFNLVMSHPRCVNEITLSLNSRNP---RTKALVLELLAAVCLVRGGHDIILSAFDNFKEEA KTHSNKIVETTIQNTQPKPPRTALFHYINRSKNITIMPYREKVSKEKDRFEKLMEYFIH-DDNNIDFMVACMQFINIVVH SVENMNFRVHLQYEFTHLGLDKYLES---LKETESEKLKVQIQAYLDNVLDVGALLEDAENRGGVLDHVDELQEHNIQLS ARLQEVENQSAERISELETQLLQSSKEIELLRQIIG--------------------------LQVCISTSQESLRESCSQ VGSLRERLSTSVSQTNSELEQKIQELQEKGLIRVGRNPSGGLD----------------------------IQVVPVTVV EYVQTPTT--EPS----------------SPSPYLGHARS---------------------------------GPP---- ------------------------------------PPPPPPGCG----PPLPPPPPG---------------------- ------------------------GGPPLPPGAVDTQS-------------------------------GLKSKRSIQTK FRMPLLNWQALKPNQVTGTVFNDLDDEQILEELNMEDFEEQFKTRAQGNAADLSKVKKKMVQKAPSK-------TSLIDA NKAKNLAITLRKGGMR-----------YDQ-SLSID-FLELLEHFIPSDFEMKLLVNYEKE-GRPLDELTHEDQFILRFG KIPRLNQRINTLTFMGNFPDTIKRLQPQLNSIIAAS-MSIKSSAKLKKILE---IVLAFGNYMNSSKRGAAYGFRL-QSL DLLLETKSTDRKQTLLHFITSIIQEKYPDLVNFYTDLQFVDKAAL--VSLDGILQDIRTLERGMEMTKKEFLV---QDDS TVLKEFIKVNSEHLDSLIKDSKTAQ-------EAYLSVVEYFGENPKTTQPSMFFPIFGRFIKAYKT----AKQ------ -ELEQKKKMESESQEVKESP-SPNKA-------VSPKGPG-MPKMPQMDLIAELK--KKQL--KPPVRE--GKDGALEDI ITDLR-NTPYRRTDGRR---------------------- >Oryzias_latipes-FMNL1(ENSORLP_17622) -------------------------------------------------------------------------------- --------------MNLPPDKVEILVQYDNEKKWELICDQ-PFFV--G-------------FYLGTG------------- --CSQPLERSY--KNVAPSLIEKSKNRITWAKEFLNEENRGLDVLVNYLSFINSTVKNDV----------------DTSD RNTECR-DQHT--YASVDNLN--GSPPPK--SSAS-RASRGFTLRYVTVVYRQRRPMRN------------SRVSSQKDD VHLCIMCLRAIMNYQILLSGFSQVMQHPSCVNEITLSLNDRHP---RTNALVLELLAAVCLVQGGHGIILSAFNNFKEVR AVSMGMLVMETLLSTTEETLNPTMPLVVGWCQH----SGESLVCGEKRRFEKLMEYFRS-EESNLDFMVACMQFINIVVH SVEDLNFRVYLQHEFTQLQLDDYLEQ---LKLSESDRLLVQIQAYLDNLFDVGSLLEDAEAKNAMMEHVEQLQEKNVKLN TRLQESESEAKVKVSQLENKLIQTTKELELLK-------------------------------------ERSQMSFLLLR GSLNSPSSQ-GNTDDPHKLVSRVQVLVQQGVLCVERSPTGEAV----------------------------VKVQQTADE LNGHRLVGGRIGG----------------WMDKTLWSGTS---------------------------------------- ---------------KDETDAAATSP------QPPTEESPQTPAALIPPPPPPPPLSSGGFTNQKED---------AGGE SR-----------------------SRFPTVGLKTMHR---YCKT----------------TINLVVSLGNKTKKPIQTK YRMPLLNWKPLQSYQVEGTIFSELDDTSVLKTLDMSTFEDQFKTKAQASTVDLGTLKTKASPKPSIK-------VSVVNL HRSKNLAITLRQED-----------KEYNLKALRLD-FLELLEPFIPTKHEMKLIQDFEAE-GRCLDELSEADRFMVHFS KIPRLPQRISTLTFMGNFPDSVQLIQPQLDAIIAAS-MSIKSSNKLKRILE---IILAFGNYMNSGKQGPVYGFRL-ESL NLLFETKSTDRKQTLLHFIVNVIQEQYSDLQTFYTELHFLDK-AVL-VSLDQLLADVGALERGMELTKQELCE---EEDN AVLKTFVDSNTQLLSSLVADGKTAQ-------DAYESAVLYFGEDPKSTPPSAFFSHFNRFIKAYKE----AEK------ -EQKRK--KFDLQYE-ARSGPVNAKG-------AERKSLA-PCVKPHMDLMAELK--KRQS--TPLVRE--GKDGTIEDI ISALK-SVA-FVAR