>Homo_sapiens-CACNB4(ENSP_343563) ------MSSSSYAKNGTADGPHSPTS-QVARGTTTRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------AKQKQK----------VTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Equus_caballus-CACNB4(ENSECAP_328) ------------------------------------------------------------------------GSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------AKQK----------QKVTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Mus_musculus-CACNB4(ENSMUSP_77438) -------MSSSYGKNGAADGPHSPSS-QVARGTTTRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTTT-------------------------------------AKQKQK----------VTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTSSSTPMTPLLGRNVGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGCSHDS--------------RHR----------------------- ------- >Rattus_norvegicus-CACNB4(ENSRNOP_56186) ------------------------------------------------------MYDNLYLH---GVEDSEAGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTTT-------------------------------------AKQK----------QKVTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTSSSTPMTPLLGRNVGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGCSHDS--------------RHRL---------------------- ------- >Macaca_mulatta-CACNB4(ENSMMUP_13794) ------MSSSSYAKNGTADGPHSPTS-QVARGTTTRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------GSYTYMP---------ATEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Canis_familiaris-CACNB4(ENSCAFP_13068) -----------------------------------------------------------------------QGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTSTGCPQMDWTCLGDHGTSLIRRQN------ILPHPLKNNVTRKNVSI------SRKTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------LTYNDFSSDKVIPPV---------------------------------SKLQQDTCYLLSVTV -----HYFSSSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHR----------------------- ------- >Pteropus_vampyrus-CACNB4(ENSPVAP_13662) -------MSSSYAKNGTADGPHSPTS-QVARGTTTRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------VKVVQKI---------QTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEDYPDTY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Ornithorhynchus_anatinus-CACNB4(ENSOANP0_9736) ------SSSSSYTKNGIADGPHTPTSQVVARGTTNRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------VKELTLF---------YTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLAEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEEYSDSY------- ------------------QDTYKPHRNRAS--PGGYSHDS--------------RHRL---------------------- ------- >Monodelphis_domestica-CACNB4(ENSMODP_36010) ---------------------------QVARGTTTRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSGGNSSSS---------LGEMV SGTFRATPTST-------------------------------------GRG--VI---------TTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLAEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPSAISGLQ------------------------- -----------------SQRMRHSNHSTEN-----------------------------------SPIERRS-------- -------LMASDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEEYSDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Gallus_gallus-CACNB4(ENSGALP_36967) -----------------------------------------------------------------------QGSADSYTS RPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDW WIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHG-------------------GKSSGNSSSS---------LGEMV SGTFRATPTST-------------------------------------AKQKQK----------VTEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLAEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPAAISGLQ------------------------- -----------------SQRMRHSSHSTEN-----------------------------------SPIERRS-------- -------LMTSDENYHNERARKSRNRLSSSSQHS------------------------RDHYPLVEEEYSDSY------- ------------------QDTYKPHRNRGS--PGGYSHDS--------------RHRL---------------------- ------- >Takifugu_rubripes-CACNB4(ENSTRUP_37153) ------MSRHIYTRHGIGEA-LQKPVSQVNRGTYSRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEEKEGGPQEREQQATVQLERAKTKGVAFAVRTNVSYCGALDEDVPVSGTGVSFDAKDFLHIKEKFNNDW WIGRLVKEGCEIGFIPSPLKLENIRLQQEQKRGRFHG-------------------SKSSGNSSSS---------LGEMV SGTFKPNPNSA-------------------------------------GKQKQK----------VAEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARALQLVVLDADTINHPGQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAAEKLAQCPS-EMFDIIL DENQLEDACEHLAEYLEAYWRATHTSLSTPLNPLLGRNLGSTALSPYPAAIQA--------------------------- ------------------QRNRNSNHAMTDH----------------------------------SPVERRT-------- -------LMPADENYHNERARKNRNRLSSGSQHS------------------------RDHSPLVEEDYPDPY------- ------------------QDSYKPHRNRGS--PGGYSQES--------------RHRI---------------------- ------- >Gasterosteus_aculeatus-CACNB4(ENSGACP_1586) ------MSRHIYSRHGAGDG-TQKPVFQVRTPERSTTSTSFIL-------RQVRTPERSTTS---TSFILRQGSADSYTS RPS-DSDASLEEEKEAGRQEKEQQAAAQLERAKTKAVAFAVRTNVSYCGALDEDVPAGGTAVSFDAKDFLHIKEKYNNDW WIGRQVKEGCDVGFIPSPLKLESIRLQQEHKRGRLHGR--------------RHGGSKSSGNSSSS---------LGDMA TGSFKPTPSAA-------------------------------------GKQKQK----------VAEHVPPYDVVPSMRP LVLVGPSLKGYEVTDMMQKALFDFLKHRFDKRVSITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARCLQLVVLDADTVNHPAQLAKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAAEKLAQCPS-EMFDIIL DENQLEDACEHLAEYLEAYWRSTHASPSTPLNPLLGRNLGSTALTPYPAAIQAYQ------------------------- -----------------AQRNRNSNHTTTDL----------------------------------PPLERHC-------- -------LMPADEN------HKNHNRLSSGSQYS------------------------RDHTPLVEEDYQDPY------- ------------------QDSYKPHRNRGS--PGVFSQDSS-------------RHQH---------------------- ------- >Takifugu_rubripes-CACNB4(ENSTRUP_16303) ------MSRHIYIRNKLGEG-IQAPIFQVNRGTYSRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEEREVQAQEREQLATIQLERAKTKPVAFAVRTNVSYCGALDEDVPVPATAISFDAKDFLHIKEKFNNDW WIGRLVKEGCEIGFIPSPLKLENIRLQQEQKRGRVQG--------------------KSGGNSSSS---------VEDEV SASIRPLISSA-------------------------------------GKQKQK----------VTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLLKTSLAPIIVHVKVSSPKVLQRLVKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDVIL DENQLEDACEHLAEYLEAYWKATHTSMATPLNPLLGRNLGPTILTPYPSTISGLQQ------------------------ -----------------SQRMRQSNHTGDHS----------------------------------TSNERRN-------- -------LMTSEENFHNERAHKGRNRMSSGSQHS------------------------REHQ-DPYQDYQDPY------- ------------------QDAYKPHRNRSS--PGSYSHDS--------------RHRL---------------------- ------- >Gasterosteus_aculeatus-CACNB4(ENSGACP_19536) ------MSRHIYIRNKIGEG-IQAPIFHVNRGTYSRRS-------------RLKRSDGSTTS---TSFILRQGSADSYTS RPS-DSDVSLEEEREVQAQEREQQAATQLERAKTKPVAFAVRTNVSYCGALDEDVPVPATAISFDAKDFLHIKEKFNNDW WIGRLVKEGCEIGFIPSPLKLENIRLQQEQKRGRVQG--------------------KSGGNSSSS---------VEDEV SASIRPLISSA-------------------------------------GKQKQK----------VTEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS-LAEVQSEIERIF ELARSLQLVVLDADTINHPAQLLKTSLAPIIVHVKVSSPKVLQRLVKSRGKSQSKHLNVQLVAADKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHTSLATPLNPLLGRNLGPTTLTPYPTSISGLQ------------------------- -----------------SQKIRQSNNTGDHS----------------------------------TPNERRN-------- -------LMTSDENYHNERAHKGRNRMSSGSQHS------------------------RDQQ-DHYQDYQDPY------- ------------------QDAYKPHRNRSS--PGSYSHDS--------------RHRL---------------------- ------- >Takifugu_rubripes-CACNB3(ENSTRUP_1184) -MVQVKMSKSPVDPLSAVETGSQSNYFQPNSSAGPVGARAAPFLKLPKRKSRFKRSDGSTSSDTTSSFIKRQGSADSYTS RPS-DSDLSAEEDREAYRREAERQAQLQLDRAKSKPVAFAVKTNVSYCGALDEDCPVQGAAVNFDAKDFLHIKEKYNNDW WIGRLVKEGADIAFIPSPLRLEAMRLKQEQKQRSA-----------------GIPSLRKAGGNSSS---------LGDMV TGSWRTTPPSAGEFCCSYKLNRSKNSVSGRRQG---------NGSSRKLKLKPENSCRHLDSAEFNEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADLSLAKRSVLN---KRPIMERSNTRSS-LAEVQSEIERIF ELAKSLQLVILDADTINHPAQLAKTSLAPIVVYVKVSSPKVLQRLVKSRGKSQSKHLNVQMMAADKLSQCPP-DMFDVIL DENQLEDACEHLAEYLEVYWRATHLPGNTPLNPLLDQ-----SLMTPPSAMSSLQFC----------------------- ----------PSVLQNKNQSQPHEVVDLEADEEEEEEVG----------------------EEAHSPLEQDS-------- -------LMPSDE------ASDSLSRGQRGSPST------------------------RGGE--EEEEGEDEYTSPRHTR T----------------YRDMYPPHHGHTGAAHSANGHES--------------QDRLLRHEAQQGHNQRNSRQRSRPWP RDTY--- >Gasterosteus_aculeatus-CACNB3(ENSGACP_11323) ----------------------------LYSHIG--------------YRTGLKK--------------KRKGSADSCTS RPS-DSDLSLEEDQEASRREAERQAQLQLERAKSKPVAFAVKTNVSYCGALDEDCPVQGAAINFETKDFLHIKEKYNNDW WIGRLVKEGADITFIPSPVKLEAMRIKQEQK------------------------AAARKGGNAS--------------- SGGWRSTPPSA-------------------------------------AKQKPKQ----------TELVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLN---KKAIMERSNTRSS-LAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLLKTSLAPIIVYVKVSSPKVLQRLIKSRGKSQSKHLNVQMMAGDKLAQCPP-EMFDVIL DENQLEDACEHLAEYLDIYWRATHLPCSAPVNPLLDQ-----SEVTPPSANSSQQV------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------- >Monodelphis_domestica-CACNB3(ENSMODP_12462) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEARDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLETIRLKQEQKAR--------------------------RSGNPS-------------GD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSTARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVYVKVSSPKVLHRLIRSRGKSQMKHVNVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHYPAPGPG------------LLGPPSAIPDLQN------------------------ ------------------QQLLGERG------------------------------------GECSPLERDS-------- -------LMPSDE------ASESSHQAWTGSSQR------------------------SSHH--LEDEYTDVY------- ------------------QDLYQPHRQHTSGLPSANGQDP--------------QDRLLARNSEHNYNERN-WQRNRPWP KDSY--- >Canis_familiaris-CACNB3(ENSCAFP_13041) -----------------------------------------------------------------------QGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARKHLRLLNGVQDVHTHTSRLTSLSALRRSGNPSS---------L--TD IGNRRSPPPSLG-------------------------------------SFSKKPSRSKSRSILQAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSAIPGLQVP----------------------- ----------ISSSQAKPAKALPPPGPGDCPWPPARRPKDCRSQAEPEFCRSPKLQFSMSQVEDASPSLHHL-------- -------LYPGTERYE---ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHNHNDRN-WQRNRPWP KDSY--- >Mus_musculus-CACNB3(ENSMUSP_3442) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--GD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSAIPGLQN------------------------ ------------------QQLLGERV------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHDHNDRN-WQRNRPWP KDSY--- >Rattus_norvegicus-CACNB3(ENSRNOP_17490) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--SD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLDDACEHLAEYLEVYWRATHHPAPGPG------------MLGPPSAIPGLQN------------------------ ------------------QQLLGERG------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHDHNDRN-WQRNRPWP KDSY--- >Homo_sapiens-CACNB3(ENSP_301050) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--SD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSAIPGLQN------------------------ ------------------QQLLGERG------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHNHSDRN-WQRNRPWP KDSY--- >Equus_caballus-CACNB3(ENSECAP_10205) ------------------------------------------------------------------------GSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--SD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSAIPGLQN------------------------ ------------------QQLLGERG------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHNHNDRN-WQRNRPWP KDSY--- >Macaca_mulatta-CACNB3(ENSMMUP_11056) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--SD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSVIPGLQN------------------------ ------------------QQLLGERG------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSRH--LEEDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHNHNDRN-WQRNRPWP KDSY--- >Pteropus_vampyrus-CACNB3(ENSPVAP_9250) -------------------------MYDDSYVPG------------------FEDSE--------------AGSADSYTS RPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDW WIGRLVKEGGDIAFIPSPQRLESIRLKQEQKAR--------------------------RSGNPSS---------L--SD IGNRRSPPPSLA-------------------------------------KQKQK----------QAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS-IAEVQSEIERIF ELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPP-ESFDVIL DENQLEDACEHLAEYLEVYWRATHHPAPGPG------------LLGPPSAIPGLQN------------------------ ------------------QQLLGERG------------------------------------EEHSPLERDS-------- -------LMPSDE------ASESSRQAWTGSSQR------------------------SSHH--LEDDYADAY------- ------------------QDLYQPHRQHTSGLPSANGHDP--------------QDRLLAQDSEHNHNDRN-WQRNRPWP KDSY--- >Homo_sapiens-CACNB1(ENSP_377840) MVQKTSMSRGPYPPSQEIPMEVFDPSPQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASAK-QKQ----------------------------------------------KSTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ------------------------- ----------GPYLASGDQPLE---RATGEHASMHEYPG----------------------ELGQPPGLYP--------- ----SSHPPGRAGTLRALSRQDTFDADTPGSRNS------AYTEL-------------GDSCVDMETDPSEGPGL----- ----GDPAGGG-----TPPARQGSWEDEEEDYEEELTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG RGVYIR- >Equus_caballus-CACNB1(ENSECAP_1519) MVQKTSMSRGPYPPSQEIPMEVFDPSPQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPTPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASAK-QKQ----------------------------------------------KSTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ------------------------- ----------GPYLASGDQSLE---RATGEHPSVHESPG----------------------EPGHPPGLYP--------- ----SSHPPGRAGTLRALSRQDTFDADTPGNRNS------AYTEL-------------GDSCVDMETDPSEGPGL----- ----GDPAGGS-----TPPARQGSWEDEDDDYEEELTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG RGVYIR- >Macaca_mulatta-CACNB1(ENSMMUP_34642) MVQKTGMSRGPYPPSQEIPMEVFDPSPQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASAK-QKQ----------------------------------------------KSTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ------------------------- ----------GPYLASGDQPLH---RATGEHASVHEYPG----------------------ELGQPPGLYP--------- ----SSHPPGRAGTLRALSRQDTFDADTPGSRNS------AYTEL-------------GDSCVDMETDPSEGPGL----- ----GDPAGGG-----TPPARQGSWEDEEEDYEEELTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG RGVYIR- >Canis_familiaris-CACNB1(ENSCAFP_24296) -----------------------------------------------ITLGWLELETSMMGG--TSVPSEAQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASAF-ELDP-------LELDDEEA-ELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALASSPAPVSNLQ------------------------- ----------GTRGSETDSRKG---PSMGALPWQLLPIS----------------------EFTPLNNSREKAM------ ----NSHPPGRVGTLRALSRQDTFDADTPGNRNS------AYTEL-------------GDSCVDMETDPSEGPGL----- ----GDPAGGS-----TPPARQGSWEDEEEDYEEELTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG RGVYIR- >Mus_musculus-CACNB1(ENSMUSP_99433) MVQKSGMSRGPYPPSQEIPMEVFDPSPQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASGN-EMTNFAFELDPLELEEEEA-ELGEHGGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLSFWGGLEASPRGGD AVAQPQEHAMGPYLASGDQPLD---RATGEHASVHEYPG----------------------ELGQPPGLYP--------- ----SNHPPGRAGTLRALSRQDTFDADTPGSRNS------AYTEP-------------GDSCVDMETDPSEGPGP----- ----GDPAGGG-----TPPARQGSWEDEE-DYEEEMTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG QGVYIR- >Rattus_norvegicus-CACNB1(ENSRNOP_30299) MVQKSGMSRGPYPPSQEIPMEVFDPSPQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASGN-EMTNFAFELDPLELEEEEA-ELGEHGGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLSFWGGLEASPRGGD AVAQPQEHAMGPYLASGDQPLD---RATGEHASVHEYPG----------------------ELGQPPGLYP--------- ----SNHPPGRAGTLRALSRQDTFDADTPGSRNS------AYTEP-------------GDSCVDMETDPSEGPGP----- ----GDPAGGG-----TPPARQGSWEEEE-DYEEEMTDNRN---------RGRNKARYCAE--GGGPVLGRNKNELEGWG QGVYIR- >Monodelphis_domestica-CACNB1(ENSMODP_15872) -------------------MEVFDPRQQ---------------GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTS RPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSRGDEAPVQGMAITFEPKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLDSLRMVQEQKMRQNRLS-----------------SSKSGDNSSSS---------LGDVV TGTRRPTPPASAF-ELDP-------LELEEEEA-ELYDHTGSPKPSVSSITTPSPHGKRIPFFKKAEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIVERSNTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPAQLAKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP-EMFDIIL DENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ------------------------- ----------GAYRVPGDQAPE---RAVGERASLHEYQG----------------------E---PQGHHTG-------- ----SSHPPGRAGTLRSLSRQDTFDADASGNRNS------AYIEL-------------GDSCVDMETDPSEGPGK----- ----GDPAGGS-----SPPARQGSWEEED--EEEELPDNRNRATP-----RGPAKPQYCPE--GGGTMLGRNKNELEGWG RGVYNR- >Takifugu_rubripes-CACNB1(ENSTRUP_42127) MVQKSSMSRTPSTSTQEIQMDMFDHHPHTQFAPVGAGVAGRTQGKYAKRKSRFKRSDGSTSSDTTSNSFVRQGSADSYTS RPS-DSDVSLEEDPEALRKEADRQALATLEKAKTKPVAFAVRTNVGYNPGPSDDVPVQGMAISFEAKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLENTRQLQEQRMRQNRLS-----------------SSKSG--GSSS---------L-DVT TGTRRPTPPGTAHVDMSTVTFDADPLDLDAEEPPEFQGDHRSPKAMSGSVTSPQANVHRLPFFKKMEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHKFEGRISITRVTADISLAKRSVLNNPSKHTIIERSSTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPSQLAKTSLAPIIVYIKIASPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDIIL DENQLEDACEHLADYLEAYWKATHPPSSNPPNPLLNRTMATAALAASPEPVSNLQ------------------------- ----------VQVLTSLRRNLD-LWPDMDGAVANEDLGA----------------------KPQQQQQAHMR-------- ----SSRGQLRGGSGRGLSRQDTFDSETQGSRDS------AYTEA-------------GDSCMDIETDPYEEPEPYRGG- ----GSRLHLA-----QHHGRQASWEDEGAEPDQENLNHPPMPSQPQPHGRAKLRERYCQDPVDTGANKSRNKN-QDDWG RDVYIR- >Gasterosteus_aculeatus-CACNB1(ENSGACP_12280) MVQKSSMSRTPSTSTQEIQMDMFDHHPH-------------TQGKYGKRKSRFKRSDGSTSSDTTSNSFVRQGSADSYTS RPS-DSDVSLEEDPEALRKEADRQALATLEKAKTKPVAFAVRTNVGYNPGPSDEVPVQGMAISFEAKDFLHIKEKYNNDW WIGRLVKEGCEVGFIPSPVKLENTRLLHEQKMRQNRLS-----------------SSKSG--GSSS---------L-DVA TGTRRPTPPGTG-----------------------------------GPAKQKQ---------KSMEHVPPYDVVPSMRP IILVGPSLKGYEVTDMMQKALFDFLKHKFEGRISITRVTADISLAKRSVLNNPSKHTIIERSSTRSS-LAEVQSEIERIF ELARTLQLVALDADTINHPSQLAKTSLAPIIVYIKIASPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDIIL DENQLEDACEHLADYLEAYWKATHPPSSNPPNPLLNRTMATAALAASPEPVSNLQ------------------------- ----------GPYLVHGEQKLEGPLTECGGSGTLHDYQT----------------------DTGGKPHPYLR-------- ----SSRGQLRGGSGRGLSRQDTFDSETQGSRDS------AYTEA-------------GDSCMDIETDPYEEPEPYRGGS G---GSRLHLA-----QHHGRQASWEDEGAEPDQENLNHPAVPSQTQAHGRAKLRERYCQDPVDTGANMSRNKN-QDDWG RDVYIR- >Takifugu_rubripes-CACNB2(ENSTRUP_19753) -MKATWIRLLKRAKG------------------------------------------------GHVKSSDACGSADSYTS RPS-DSDVSLEEDKEAVRREAERQAQAQLDKAKTKPVAFAVRTNVSYSPSHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKIENTRILQEQRAKQGKFH-----------------SSKLGANSSSS---------LGEVV PNSRKSTPPSS--------ALDIDATDLDPEDN-ELPVNLRSPKASPNTVMSPLSKEKRMPFFKKTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSN-LAEVQSEIERIF ELARTLQLVVLDADTINHPSQLGKTSLAPIIVYVKITSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-EMFDIIL DENQLEDACEHMADYLEAYWRSTHPSSSNPPNPVVA-KLSTATLPSNAAPISDVQ------------------------- ---------------GSSAE-QKGEKALVERK-----GS----------------------RRNQHVHHRSSSTRTDHHN HHHHHHHHHHHSGRARGLSRQETLDSETPESRES---KDSSYIDPRAQLHHQ----EVEEPPPHRDHNHHHHHHHHRSG- ----PDEAGQS-----TGHHRSKEREQDHNERNKQRSHHHRPTRDH--PHHSYDRDRDRD-----GEVAPKKRGDTGDWT RDSYIYQ >Gasterosteus_aculeatus-CACNB2(ENSGACP_5344) -------------------------------------------------------------------------------- --------------------------------------------------------------------------KFNNDW WIGRLVKEGCEIGFIPSPVKLENTRILQEQRAKQGKFH-----------------SSKLGANSSSS---------LGEVV PNTRKSTPPSS--------AIDIDATDLDPEDN-EPPVNLRSTKASPNTVMSPLAKEKRMPFFKKAEHVPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSN-LAEVQSEIERIF ELARTLQLVVLDADTINHPSQLGKTSLAPIIVYVKITSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-EMFDIIL DENQLEDACEHMADYLEAYWKSTHPTSCNPPNPLLT-SLPAATLPPGPALVSGVQ------------------------- ---------------VRKQRPHRATPAASGRETHSNGAS----------------------RRAPHIHHRSSSTRTEHQN -----HHHHHHNSRGRGLSRQETLDSETPESRESRESKDSAYNEPRTQLHHQEQGEELEEPLPHRDHNHHHHHHHHRGGG GGGGAEEAGRGGGGGVAGHHRSKEREQDHNERNKQRSHHHRPARDH--HHHYYDRDRDRDR---EGEVAPKKRGEAGEWA RDSYIHQ >Ornithorhynchus_anatinus-CACNB2(ENSOANP_9080) -----------------------------------------------------------------------QGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLDKAKSKPVAFAVRTNVSYSAAHDDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKESCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKAGGNSSSS---------LGDVI PSSRKSTPPSSVGNRMSRFAVDIDAAGLDAEEG-DTPANHRSPKPNANSVTSPHSKEKRIPFFKKTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRVSITRVTADISLAKRSVLNNPSKHVIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIVVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAAEKLAQCPP-ELFDVIL DENQLEDACEHLADFLE-YWKAAHPPGSPATHALPGATLSGSPGPVS--------------------------------- ------------------------APQFWIS----------------------------------TSRRAGVS------- ------------------------------------------------------------YVITLEANQRE--------- ----GDRGARP-------QGRGT--------------------------------------------------------- ------- >Gallus_gallus-CACNB2(ENSGALP_13972) -MKATWIRLLKRAK------------------------------------------------GGRLKNSDICGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVGYSAAHDDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQKAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-EMFDVIL DENQLEDACEHLADYLEAYWKATHPPSSNPPNQLLTRTLATATLPISPGPNINLQQ------------------------ -------------GSQGDQRNDHSVPERSNSQIEEEARV----------------------EPIKKSHHR--SS------ ----TQHHNHRSG-VRGLPRQETFDSETQDSRDS------AYVEPKEDYSHEHG----DHYDSHRDHNHRDESHG--DH- ----RHRESRH-------RSKERDREQDHNECNKQRSRHK-------------SRDQYCDK---DGEVISKKRNDAGEWN RDVYIRQ >Monodelphis_domestica-CACNB2(ENSMODP_12021) -MKATWIRLLKRAK------------------------------------------------GGRLKNSDICGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHIPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDVIL DENQLEDACEHLADYMEAYWKATHPPSSNPPNPLLSRTLATASLPISSTPASNSQ------------------------- -------------GSQ-DQRNDYSAPTRSASQAEEEPCL----------------------EPVRKSQHRSSSS------ ----AQHHNHRSGPSRGLSRQETFDSETQDSRDS------AYVESKEDYSHEHGG---DHYAPHRDHNHREDLHGSSDH- ----RHRESRH-------RSREADREQDHNECHKQRSRHK-------------SKDRYCDK---DGEVISKKRNEAGDWN RDVYIRQ >Canis_familiaris-CACNB2(ENSCAFP_6689) -MLDRRLMSP------------------------------------------------------QTKCIIPGGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRIPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDVIL DENQLEDACEHLADYLEAYWKATHPPSSHLPNPLLSRTLATSTLPSSPTQASNSQ------------------------- -------------GSQ-DQRTERSAPARSVSQAEEEACP----------------------EPVKKTQHRSSS------- ----AQHHGHRSGTSRGLSRQETFDSETQESRDS------AYVEPKEDYSHEHV----DHYAPHRDHNHRDEPHGSSEH- ----RHRESRH-------RSRDLDREQDHNECNKQRSRHK-------------SKDRYCDK---DGEGISKKRNEAGEWN RDVYIRQ >Equus_caballus-CACNB2(ENSECAP_12041) -MLDRRLTSS------------------------------------------------------QTKCFIPGGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKSKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDVIL DENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSTLPVSPALASNSQ------------------------- -------------GSQGDQRTDRSAPARSASQAEEEPCL----------------------EPVKRSQHRSSSS------ ----AQHHNHRSGTSRGLSRQETFDSETQESRDS------AYVEPKEDYCHEHV----DHYAPHRDHNHRDEPHGSSEH- ----RHRESRH-------RARDLDREQDHNECNKQRSRHK-------------SKDRYCDK---DGEGISKKRNEAGEWN RDVYIRQ >Homo_sapiens-CACNB2(ENSP_320025) -MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDVIL DENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ------------------------- -------------GSQGDQRTDRSAPIRSASQAEEEPSV----------------------EPVKKSQHRSSSS------ ----APHHNHRSGTSRGLSRQETFDSETQESRDS------AYVEPKEDYSHDHV----DHYASHRDHNHRDETHGSSDH- ----RHRESRH-------RSRDVDREQDHNECNKQRSRHK-------------SKDRYCEK---DGEVISKKRNEAGEWN RDVYIRQ >Macaca_mulatta-CACNB2(ENSMMUP_9770) -MVQSDMSKSPPTAAAAVAPEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AVDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPP-ELFDVIL DENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ------------------------- -------------GSQGDQRTDRSAPIRSASQAEDEPSV----------------------EPVKKSQHRSSSS------ ----APHHNHRGGTSRGLSRQETFDSETQESRDS------AYIEPKEDYSHDHV----DHYASHRDHNHRDETHGSSDH- ----RHRESRH-------RSRDVDREQDHNECNKQRSRHK-------------SKDRYCEK---DGEVISKKRNEAGEWN RDVYIRQ >Mus_musculus-CACNB2(ENSMUSP_110371) -MVQSDTSKSPPVA--AVAQESQMELLESAAPAGALG--AQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVIL DENQLEDACEHLADYLEAYWKATHPPSGNLPNPLLSRTLASSTLPLSPTLASNSQ------------------------- -------------GSQGDQRPDRSAP-RSASQAEEEPCL----------------------EPVKKSQHRSSS------- ----ATHQNHRSGTGRGLSRQETFDSETQESRDS------AYVEPKEDYSHEHV----DRYVPHREHNHREETHSSNGH- ----RHRESRH-------RSRDMGRDQDHNECIKQRSRHK-------------SKDRYCDK---EGEVISKRRNEAGEWN RDVYIRQ >Rattus_norvegicus-CACNB2(ENSRNOP_37354) ------------------MKATWIRLLKRAK--------------GGRLKN----------SDICG-------SADSYTS RPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDW WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFY-----------------SSKSGGNSSSS---------LGDIV PSSRKSTPPSS--------AIDIDATGLDAEEN-DIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS-LAEVQSEIERIF ELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVIL DENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLPLSPTLASNSQ------------------------- -------------GSQGDQRTDRSAP-RSASQAEEEPCL----------------------EPVKKSQHRSSS------- ----ATHQNHRSGTGRGLSRQETFDSETQESRDS------AYVEPKEDYSHEHV----DRYVPHREHNHREESHSSNGH- ----RHREPRH-------RTRDMGRDQDHNECSKQRSRHK-------------SKDRYCDK---EGEVISKRRSEAGEWN RDVYIRQ >Anopheles_gambiae-CACNB1(XP_317433) TGIAPKISGLEEDWRPERPMVQRASSDAPSVSGGHRESRG---IGLGLGYTSFQSAGYNKLFTQVSLTATHGGSADSNYS QPS-SDLS-LDEEKESLRREKERQALGQLEKARSKPVAFAVRTNVSYDGSLDDDSPVHGSAVSFEVGDFLHIKEKYDNNW WIGRLVKEGCEVGFIPSPVKLEHIRMQVRTET--PRLYT-----------------SKGS---SSS----------GNLG ASGVPGAEPSRGS------------TPPTPDDSDSMGASRHGKTPLATP----PTKEKRKPFFKKQETSSPYDVVPSMRP VVLVGPSLKGYEVTDMMQKALFDFLKHRFESRIIITRVQADISLAKRSLMNNPSKRAIMERSNSRSSCLAEVQAEIERIF ELARTLQLVVLDCDTINHPSQLAKTSLAPTIVYLKIASSKVLQRLIKSRGKAQAKNLSVQMVAAEKLSQCPP-EMFDVIL DENQLEEACNHLAEYLEAYWRATHPPVRPTP------------SVPRPLPSQEAS------------------------- ------------------------------------------------------------------PSGEQ--------- ----------------PGRMGPPP---PTG------------------------------------RLFVST-------- -------------------------------------------------------------------------------- ------- >Branchiostoma_floridae-CACNB1(XP_002598413) ------MAFVVYTYYPE-----------PPVSDAGKIER----------------------------QRKRKGSAESYNS RPSESDISSQDEDREALRRESEKQALTQLEKARTKPVAFAVRTNVGYDPMADDDSPVQGKAVRFEARDFLHIKEKYNNEW WIGRLVKEGCDVGFIPSPVKLENIRLQQSAAQNRSRIYS-----------------SKASDRESASESELLTVEGTGNYR LSSVEGLDSEQNG------------VDLG-EDSDSLSNVRRSTQSVTTPSLTTPTKKEKRPFFKKVENIPPYEVVPSMRP VVFVGPSLKGYEVTDMMQKALFDFLKHRFEGRIVITRITADIALAKRTMNNSSSK--LSDRSATRGQGVAEVQAEIERIF ELARSLQLVVLDCDTINHPAQLAKTSLAPLVCYVKIGSPKVLTRLIKSRGKSQSRHLNVQLVAADKLAQCPP-EMFDVIL DENQLDEACEHLAEYLEAYWRATHPPLPKPD------------VPPGPLPTAELAR------------------------ -------------------------------------------------------------KIQNTPSSRQGPD------ -------LVHDDRSPRSPRRGPPPHDLPTSHSPE------------------------YNANSRVDRTHIDNHPEP---- ------------------HLDRHGHRDLGGHRDMRDPRREVS-----------LSRERLPHSPSRSHNRSPARNHPMREP REIAT--