>Homo_sapiens_YTHDF1 ---MSATSVDT---QRTKGQ-----DNKV---QNGSLHQKDTVHDNDFEPYLTGQSNQ------------------SNSY PSMSDPYLSS------------YYPPSIGF-------PYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------TYP PSSLGGTVV-DGQPGFH--SDT-LSKAP--GMNSLEQGMVGLKIG---DVSSS--AVKTVGSVVSSVALTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKTKSG-P-VMGGGLPPPPI---KHNMDIGTWDNKGPVPKA PVP-------------------------QQAPSPQAAPQPQQ-VAQP--------------------------------- ---LPAQPP-----ALAQPQYQSPQQPP------------------QTRWVAPRNRNAAFGQS---------------GG AGSDSNSPGNVQPNSA-------------------PSVESHPVLEKLKAAHSYNPKEFEWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRCMSSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIISSYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQSRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Macaca_mulatta_YTHDF1 ---MSATSVDT---QRTKGQ-----DNKV---QNGSLHQKDTVHDNDFEPYLTGQSNQ------------------SNSY PSMSDPYLSS------------YYPPSIGF-------PYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------TYP PSSLGGTVV-DGQPGFH--SDT-LSKAP--GMNSLEQGMVGLKIG---DVSSS--AVKTVGSVVSSVALTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKTKSG-P-VLGGALPPPPI---KHNMDIGTWDNKGPVPKA PVP-------------------------QQAPSPQAAPQPQQ-VAQP--------------------------------- ---LPAQPP-----PVAQLQYQSPQQPP------------------QTRWVAPRNRNAAFGQS---------------GG AGSDSNSPGNVQPNST-------------------PSVESHPVLEKLKAAHSYNPKEFDWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRCMSSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIISSYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Callithrix_jacchus_YTHDF1 ---MSATSVDA---QRTKGQ-----DNKV---QNGSLHQKDTVHDGDFEPYLTGQSNQ------------------SNSY PSMSDPYLSS------------YYPPSIGF-------PYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------TYP PSSLGGTVV-DGQPGFH--SDT-LSKAP--GMNSLEQGMVGLKIG---DVSSS--AVKTVGSVVSSVALTGVLSGNG--- -----GAN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKTKSG-P-VMGGALPPPPI---KHNMDIGTWDNKGPVPKA PVP-------------------------QQAPSPQAATQPQQ-VAPP--------------------------------- ---VPTQPP-----PLAQPQYQSPQQPP------------------QTRWVAPRNRNTAFGQS---------------GG AGSDSNSPGNVQPNAA-------------------PSVESHPVLEKLKAAHSYNPKEFDWNL--RSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRCMSSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIISSYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Mus_musculus_YTHDF1 ---MSATSVDP---QRTKGQ-----DNKV---QNGSLHQKDAVHDNDFEPYLSGQSNP------------------SNSY PSMSDPYLSS------------YYPPSIGF-------PYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------TYP PSSLGGTVV-DGQTGFH--SDS-LNKAP--GMNSLEQGMVGLKIG---DVTTS--AVKTVGSVVNSVALTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKTKSG-P-IVGGALPPPPI---KHNMDIGTWDNKGPAPKA SAP-------------------------QQTPSPQAAPQPQQ-VAQP--------------------------------- ---LPVQPP-----PLVQPQYQSPQQPL------------------QPRWVAPRNRNAAFGQS---------------GG ANSDSNSVGNAQPTSA-------------------PSVESHPVLEKLKAAHSYNPKEFDWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAFRSMSSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Rattus_norvegicus_YTHDF1 ---MSATSVDP---QRTKGQ-----ENKV---QNGSLHQKDAVHDNDFEPYLSGQSNP------------------SNSY PSMSDPYLSS------------YYPPSIGF-------PYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------TYP PSSLGGTVV-DGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIG---DVTTS--AVKTVGSVVNSVALTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKTKSG-P-IVGGTLPPPPI---KHNMDIGTWDNKGPAPKA SAP-------------------------QQTPSPQAAPQPQQ-VAQP--------------------------------- ---LPVQPP-----PLVQPQYQSPQQPL------------------QPRWVAPRNRNAAFGQS---------------GG ANSDSNSVGSAQPTSA-------------------PSVESHPVLEKLKAAHSYNPKEFDWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAFRSMSSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Canis_familiaris_YTHDF1 -------------------------------------------------------------------------------- --MADPYLSS------------YYPPSIGF-------PYSLNEAPWSTGGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQA-----QSSAYGSSY-------TYP PSSLGGTIV-DGQTGFH--SET-LNKAP--GMNSLEQGMVGLKIG---DVTTS--AVKTVGSVVSSVAMTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKAKSG-P-VIGAALPPPPI---KHNMDIGTWDNQGPVPKA PAP-------------------------QQAPAPQSAPQPQP-VVQP--------------------------------- ---LPTQPP-----PLAQPQYPSPQQPP------------------QTRWVAPRNRNAAFGQS---------------GG TSSDGNSPGNTQPSSA-------------------PTVESHPVLEKLKAAHSYNPKEFDWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAFRAASSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKP---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Felis_catus_YTHDF1 -------------------------------------------------------------------------------- --MADPYLSS------------YYPPSIGF-------PYSLNEAPWSTGGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNS---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQA-----QSSAYGSSY-------TYP PSSLGGTIV-DGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIG---DVTTS--AVKTVGSVVSSVAMAGVLSGSG--- -----GTS-VNMPV-----SKPTSWAAIASKPAKPQP-KMKAKSG-P-VIGAALPPPPI---KHNMDIGTWDNKGPVPKP PAP-------------------------QQAPAPQPAPQPQP-VVQP--------------------------------- ---LPAQPP-----PLAQPQYPSPQQPP------------------QTRWVAPRNRNAAFGQS---------------GG AGGDGNSPGSAQPHSA-------------------PSVESHPVLEKLKAAHSYNPKEFDWNL--KSGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAFRAAGSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLRIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Myotis_lucifugus_YTHDF1 FPYLKVIFKNA---NTIFVS-----AILV---QNGSLHQKDTVHDNDFEPYLSGQSNQ------------------SNSY PSMADPYLSS------------YYPPSIGF-------PYSLNEAPWSTGGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQA-----QSSAYGSSY-------TYP PSSLGGTIV-DGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIG---DVTTS--AVKTVGSVVSSVAMTGVLSGNG--- -----GTN-VNMPV-----SKPTSWAAIASKPAKPQP-KMKAKGG-P-VIGAALPPPPI---KHNMDIGTWDNKGPVPKA LAP-------------------------QQVPAPQSAPQPQP-VVQP--------------------------------- ---LSVQPP-----PLAQPQYQSSQPLP------------------QTRWVAPRNRNAAFGQS---------------SG TGGNSHSPGSTQSGSA-------------------LSAESHPVLEKLKAAHSYNPKEFDWNL--RSGRVFIIKSYSEDDV HRSIKYSIWCSTEHGNKRLDGAFRSVGSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gallus_gallus_YTHDF1 ---MSATSVDP---QRPKGQ-----DNKV---QNGSLHQKDTVHDNDFEPYLSGQSNQ------------------NSSY PSMTDPYLSS------------YYPPSIGF-------PYSLSEAPWSTGGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGSSY-------SYP PSSLGGTIV-DGQTGFH--NDT-LNKAP--GMNSIEQGMVGLKIGG--DVTTS--AVKTVGSVVNSAGMTGALSGNG--- -----GSN-VNLPV-----SKPTSWAAIASKPAKPQP-KMKTKTG-P-VIGGALPPPPI---KHNMDIGTWDNKGPVAKV PAP-------------------------QQIPSPQSVPQPQQQIVQP--------------------------------- ---VPAQPP-----PLTQPQYQSPQQPP------------------QNRWIAPRNRNAAFGQS---------------GG TGNDSNSAGSTQPNPV-------------------PSGESHPVLEKLKAAHSYNPKDFEWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRSMNSKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Anolis_carolinensis_YTHDF1 ---MSATSVDP---QRPKGQ-----DNKV---QNGSLHQKDTVHDNDFEPYLSGQSNQ------------------NNSY PSMTDPYLSS------------YYPHSISF-------PYSLSEAPWSTGGDPPIPYLTTYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYPHRFNFF----PENPPFS--AWGTSGS----QGQQT-----QNSAYGSSY-------SYP PSSLGGTIV-DGQTGFH--NDT-LNKAP--GMNSIEQGMVGLKIGG--DVTAS--AVKTVGSVVNSTGLACALSGNG--- -----GSS-INLPV-----SKPTSWAAIASKPAKPQP-KMKAKSG-P-VVGGALPPPPI---KHNMDIGTWDNKGPVAKV PAP-------------------------QQIPSPQSLPQPQ--IIQP--------------------------------- ---IPTQPP-----PLTQLPYQNPQPPPP-----------------QNRWVAPRNRNAAFGQS---------------GG TGNESNSLGSAPANSI-------------------PGGESHPVLEKLKAAHSYNPKDFEWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRSMNSKGP---VYLLFSVNGSGHFCGVAEMKSSVDYGTSAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------ERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Xenopus_tropicalis_YTHDF1 ----FSPKVFP----LGRSN-----NDLIS-VQNGSLHQKDSVHDNDFEQYLSGQSNQ------------------SNSY PSMTDPYLSS------------YYPPSIGF-------PYSLSEAPWSTGGDPPIPYLTPYGQLSNGDHHFMHDAV----- -----FGQPGGLGNN---IYQHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QNSAYGGSY-------SYP PSSLGGTIV-DGQTGFH--NET-LNKAP--GMNSIEQGMVGLKIGS--NVTAS--AVKTVGSVVNSVGMPSALSGNG--- -----GTS-ISMPP-----SKPTSWAAIASKPAKPQP-KAKTKPV-T-IIGGALPPPPI---KHNMDIGTWDNKGPVAKP PMP-------------------------QQIPSPQSMPPPQPQLLQP--------------------------------- ---IPAQPP-----PMSQTPYQNPPPPQQQP------------QAPQNRWVAPRNRNAAYGQG---------------GG P--DGNPLGGAQSHSA-------------------PGNESHPVLEKLKAAHSYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWL FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KLVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRK-------------------------VMAKPDSC---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Danio_rerio_YTHDF1_a ---MSTTSIDPQ---TSKGQ-----DA---KVQNGSLHQKETVHDNDFEPYLTGQSNP------------------NNSY QSMTDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYAPLSNGDHHFMHDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFP--SDT-LNKAP--GMNSLEQGMVGLKIGG--DVTGGGSGVKTVGSVI-GGGPVAAAVATGN-- ----GGTP-IGLPP-----PKPTSWAAIASKPAKPQQLKVKSKPGMP-MAGGTLPPPPI---KHNMDIGTWDNKGPVTKV ASSLPPHHHHQQQPPLHSQGHLPPHPHGLPPPPQPPMPSAQSLAQQM--------------------------------- ---AMQGPP-----PPQP--YQNHAPAP----------------PPQTRWVAPRNRNPGYGGG-----GSVDSSGSSSGG GVGNGGGGGPP---GS-------------------GAIESHPVLEKLRAAHSYNPKEFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAINGKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------VVRKNLEPAP------------------IQNRSRLDQERQN RNKQ---------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Takifugu_rubripes_YTHDF1_a ---MSATSIEPQ---RSKGQ-----ASK---VQNGSLHQKETVHDSDFEPYLSGQSTQ------------------NNSY QSITDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SET-LNKAP--GMNSLEQGMVGLKIGG--DVAGQGSGVKAVGSVI--GGPAVPTAGNG--- -----ATP-IGMPP-----PKPTSWAAIASKPAKPQQLKTKVKPGMPGSLGGALPPPPI---KHNMNIGTWD-KGPVTKG PMQ----------------------QGHMQPPPPQSLVQPQMQPMAL--------------------------------- ---QPPHHQHHQHHQPPPQPYQNHGQPP----------------QPQTRWIAPRNRNQGYGQG-----GPGQDCNC-TMG LIS-GNGGPPSSISQG-------------------PGAESHPVLDKLRASHSYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAYRAMNAKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRK-------------------------VRPPPQYC---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Takifugu_rubripes_YTHDF1_b ---MSATSIEPQ---RSKGQ-----ASK---VQNGSLHQKETVHDSDFEPYLSGQSTQ------------------NNSY QSITDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SET-LNKAP--GMNSLEQGMVGLKIGG--DVAGQGSGVKAVGSVI--GGPAVPTAGNG--- -----ATP-IGMPP-----PKPTSWAAIASKPAKPQQLKTKVKPGMPGSLGGALPPPPI---KHNMNIGTWD-KGPVTKG PMQ----------------------QGHMQPPPPQSLVQPQMQPMAL--------------------------------- ---QPPHHQHHQHHQPPPQPYQNHGQPP----------------QPQTRWIAPRNRNQGYGQG-----GPGQDCNC-TMG LIS-GNGGPPSSISQG-------------------PGAESHPVLDKLRASHSYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAYRAMNAKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRK-------------------------KKSSLNKL---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Tetraodon_nigroviridis_YTHDF1_a ---MSATSIEPQ---RSKGQ-----ASK---VQNGSLHQKETVHDNDFEPYLSGQSTQ------------------NNSY QSITDPYMSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SET-LNKAP--GMNSLQQGMVGLKIGG--DVTGQGSGVKAVGSVI--GGPTVPTAGNG--- -----ATP-IGMPA-----PKPTSWAAIASKPAKPQQLKTKVKP--------------I---KHNMNIGTWD-KGPVTK- ---------------------------VATVPPPQ--------PLGL--------------------------------- ---P---------HGLPPQGPMTQG-------------------PMQTRWIAPRNRNQGYGQG-----GLGQDCNC-TMG LIS-GNGGPPTSVSQG-------------------PGAESHPVLDKLRACHSYNPKDFDWNL--KNGRVFIIK-YSEDDI HRSI-YSIWCSTEHGNKRLDSAYRAMNAKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRK-------------------------ERQNRHKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Tetraodon_nigroviridis_YTHDF1_b ---MSAASIDPQE--TSKGQ-----DASKVSVQNGSLHQKDTVHDTDFEPYLSNQSNQ------------------NNSY QSMTDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPVPYLTPYAPLSNGDHHFMHDTV----- -----FGQPGGLSSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SDT-LSKAP--GMNTIEQGMLGLKLGG--DVAGTGSAVKSPGSVIGGGGSVAAAVAT---- -------P-IGMPT-----PKPTSWAAIASKPAKLQQQKNKNKPGAS-IAGGPLPPPPI---KHSMDIDTWDNKGTVAKM AAPLP-----------------------------QSLQSAQSLVQQM--------------------------------- ---TMPGPP-----PPPP-SYQNHSSAP----------------TPQTRWVAPRSRNFCFT------------------- --------------PE-------------------PGAESHPVLEKLRAAHSYNPREFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAMNSKGP---VYLLFSVNGSGHFCG-VEMRSPVDYGTSAGVWAQDKWKGKFDVSWL FVKDVPNSQ-RHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIITQYKHTTSIFDDFSHYEKKQEEEE------- ---------------------------------------VVKK-------------------------ERQKRIKV---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gasterosteus_aculeatus_YTHDF1_a ---MSATSIDPQ---RSKGQ-----ASK---VQNGSLHQKEAVHDNDFEPYLTGQSTQ------------------NNSY QSITDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPTFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIGG--DVGGQCSGVKAVGSVI--GGPVVAATGNG--- -----ATP-IGMPP-----PKPTSWAAIASKPAKPQQLKAKLKPGMS-NLGGALPPPPI---KHNMNIGTWD-KGPVTKV ATAPMQH-QQPMGLPP----HGMPPQGHMQ----QGPMHPPPSQSMV--------------------------------- ---Q-PQP------------YQNHNQPP----------------QPQTRWVAPRNRNQGYGQGGYGQGGPGHDGGGGVMG MMGSGNCGPPPCAGQG-------------------PGGESHPVLDKLRAAHAYNPKDFEWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAMSAKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVLK-------------------------ERQNRSKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gasterosteus_aculeatus_YTHDF1_b ---MSAASIDPQ---TTKGQ-----DASKVSVQNGSLHQKDTVHDNDFEPYLTNQSNQ------------------NNSY QSMTDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYAPLSNGDHHFMHDTV----- -----FGQPGGLSSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QSSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SDT-LSKAP--GMNSLEHGMLGLKIGG--DLTGSGLGVKSAGSL--GGGSVAAAVATGN-- ----GGAP-IGMPP-----PKPTSWAAIAGKPAKLPQQKAKNKLGAP-IVGGGLPPPPV---KHNMDIDTWENKGALNKM APPLPQQPQLH------------SHAPSLLPPLQQSLQSAQSLVQQM--------------------------------- ---TMQGPP-----LPPPQSYQNHNSAP----------------TPQTRWIAPRNRNLCYGGG------SLDSSGSSNGG GVGNGGGGGAP---PD-------------------PGSESHPVLEKLRAVHSYNPKEFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAMNSKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVNWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIAQYKHTTSLFDDFSHYEKKQEEEE------- ---------------------------------------VVKKSYEPAP------------------IQSRSRIDQEKLS RDQM---------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Oryzias_latipes_YTHDF1_a ---MSATSIDPQ---RSKGQ-----ASK---VQNGSLHQKESVHDNDFEPYLTSQSTQ------------------NNSY QSITDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QNSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIGG--DVPGQNSGVKAVGSVI--GGP-VAAAGNG--- -----ATP-IGMPP-----PKATSWAAIASKPAKPQQLKVKMKPGMP-NPGGALPPPPI---KHNMNIGTWD-KGPVTKV AAAPLQQQQQPLGLP-----HGMPPQGPMQPPSHQSLVQPQMQPIAL--------------------------------- ---Q-PQPPHHQHHHPPPQAYQNHTQPQ----------------QPLTRWVAPRNRNQGYGQN-----GPCHDGGG-VMG VVGVGHNGPPACGSQG-------------------TGGDSHPVLEKLRASHSYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAMNGKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRKTFEPPQIQNRSR----------LDQERQNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Oryzias_latipes_YTHDF1_b ---MSATSIDPQ---RSKGQ-----ASK---VQNGSLHQKESVHDNDFEPYLTSQSTQ------------------NNSY QSITDPYLSS------------YYAPSIGF-------PYPLSEAPWSTGGDPPIPYLTPYGPLSNGDHHFMPDTV----- -----FGQPGGLGSS---IYPHRFNFF----PENPAFS--AWGTSGS----QGQQT-----QNSAYGGSY-------SYP PSSLGGTLVPDGQTGFH--SDT-LNKAP--GMNSLEQGMVGLKIGG--DVPGQNSGVKAVGSVI--GGP-VAAAGNG--- -----ATP-IGMPP-----PKATSWAAIASKPAKPQQLKVKMKPGMP-NPGGALPPPPI---KHNMNIGTWD-KGPVTKV AAAPLQQQQQPLGLP-----HGMPPQGPMQPPSHQSLVQPQMQPIAL--------------------------------- ---Q-PQPPHHQHHHPPPQAYQNHTQPQ----------------QPLTRWVAPRNRNQGYGQN-----GPCHDGGG-VMG VVGVGHNGPPACGSQG-------------------TGGDSHPVLEKLRASHSYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDSAFRAMNGKGP---VYLLFSVNGSGHFCGVAEMRSPVDYGTSAGVWAQDKWKGKFDVDWL FVKDVPNSQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------EVRKIS----------------------CNPWTPVKI---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Drosophila_melanogaster_YTHDF1 ---MR-FSLFTMPHNAAKSVE------------ERNIPWSQQVDEASYENLSS-PTHDE----------------VSGND NSMQ------------------------------------FQYPPFNFKENCNTPWNNMNKG---RKANANHDSYR---- ------RHGHSIPNN---TRRDEHQVN---PWNSRKPAAQSFRNEND--------------QPSTKLDNRT--------S DEAQNQEVVAAP-----------------KKTTWASIASQPAKLTS--RAASTTSNSKKKGPGMPPPPMVPGKHNLDVNV WDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAP-PLGARAEKVHKDTENFLKYEHKGLGNNNNFSR-----AKVSP TGP-----------------------VRRNLGPQQPVHHAAPRPATNAG------------------------------- PFGPPNARR----HDGGPHPSRNSERSGNYSSFR-----------GSEFESASKFEYRDENQSRP--------------- VEATSATEELPV--------------------------DSQLVLDELKDKNNYNPKVLDLKK-AGSARFFVIKSYSEDDI HRSIKYEIWCSTDHGNKRLDDAFKERHEEGGN--IMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKWRGKFKVKWI YVKDVPNGTLRHIRLENNENKSVTNS----RDTQEVPNDKG-IEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSK--RP P--------------------MHGPDGNNHAPAPLARSFNRQADDKDRD---------RDGRGGMS---QKHFNSGGGAG FRN---------PG-------HRGGAG-SGGSHNN--------------YSEYRRGFDIHKSSSDYQFKDRDGP------ ---DFD--RENDFGSHYGSNNR--------KNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMR--------- -------------SNEYS--- >Homo_sapiens_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---NETLNKAP--GMNTIDQGMAALKLG---STEVASNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIG-QPTQGSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QPAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------TPSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKE-------------------------RQGRGK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Callithrix_jacchus_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNSSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---NETLNKAP--GMNTIDQGMAALKLG---STEVASNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIG-QPTQGSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QPAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------APSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKE-------------------------RQGRGK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Mus_musculus_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---NETLNKAP--GMNTIDQGMAALKLG---STEVASSVPKVVGSAVGSGSITS--NIVAS-- ----SSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIG-QPTQGSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QPAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------TPSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKE-------------------------RQGRGK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Equus_caballus_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------PYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---SETLNKAP--GMNTIDQGMAALKLG---STEVASNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIGQQSTQGSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QPAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------TPSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKE-------------------------RQGRGK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Dasypus_novemcinctus_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLNPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDTAMPYLTSYGQLGNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---NETLNKAP--GMNTIDQGMAALKLG---STEVASSVPKVVGSAVGSGSITS--NIVAS-- ----SSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVT KAPS--------------QALVQNIGQQPTQSSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QPAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------SSSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKVISIP-----------------LRFFREGGGL----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Myotis_lucifugus_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---SETLNKAP--GMNTIDQGMAALKLS---STEVASNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIGQQPTQGSPQPVGQQANNSPPVAQ------------------------------- -----ASVGQQTQPLPPPPP-QSAQLSVQQQ------------AAQPTRWVAPRNRGSGFGHN----------------G VDGNGVGQSQA-GSGS-------------------TPSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKN-------------------------NKSFNKSSGNN -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Monodelphis_domestica_YTHDF2 ---MSASSLLE---QRPKGQ-----GNKVQ---NGSVHQKDGLNDDDFEPYLSPQAR------------------PNNAY TAMSDSYLPS------------YYSPSIGF-------SYSLGEAAWSTGGDPPMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---NETLNKAP--GMNTIDQGMAALKLG---STDVTSNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPTSWADIASKPAKQQP-KLKTKNG---MAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QALVQNIGQQPTQVSPQPVGQQINNSPPVVQ------------------------------- -----AAAGQQPQPLPPPPPPQPTQLSVQQQ------------AAQPTRWVAPRNRGNGFGHN----------------G VDGNGVGQSQN-NSGS-------------------APSEPHPVLEKLRSINNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------NVKKE-------------------------RQGRVK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gallus_gallus_YTHDF2 -------------------------------------------------------------------------------- --MSDSYLPN------------YYSPSIGF-------SYSLGEAAWSTGGDPPMPYLTSYGQLSNGEPHFLPDAM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFA---SETLNKAP--GMNTIDQGMAALKLG---STDVASNVPKVVGSAVGSGSITS--NIVAS-- ----NSLPPATIAP-----PKPTSWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KAPS--------------QTLVQNMAQQPPQASPQPVAQQMNSSPPVAQ------------------------------- -----APGGQQSQPLPPPPP-QPTPLPVPQP------------AAQPTRWVAPRNRGSGFGQN----------------G TEGGGVGAAQP-STGT-------------------APSEPHPVLEKLRSINNYNPKDFDWNP--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------TVKKEP------------------------HGGFGMQGGSE EDVIAGGFY----------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Anolis_carolinensis_YTHDF2 ---MSASSLLE---QRPKGQ-----GTKVQ---NGSVHQKDGLNDDDIEPYLSPQAR------------------PSNAY TAMSDSYLPN------------YYSPSIGF-------SYSLGEAAWSTGSDPPMPYLTSYGQLSNGEHHFLPEGM----- -----FGQPGALGST-PFLGQHGFNFF----PSGIDFS--AWGNNSS----QGQST-----QSSGYSSNY-------AYA PSSLGGAMI-DGQSAFS---SETLNKAP--GMNTIDQGMAALKLG---STDVASNVPKVVGSAVGSGSMAG--NIVAS-- ----NSLPPATIAP-----PKPASWADIASKPAKQQP-KLKTKNG---IAGSSLPPPPI---KHNMDIGTWDNKG--PVA KNPS--------------QGLVQNIGQPPTQISPQPLGQQMSNSPPAVQ------------------------------- -----PSTGQPPQPLPPPPTPQPTQLPVQQQ------------AAQPARWVAPRNRGNGFGQN----------------G VDGTAVGQSPA-ASGS-------------------APLEPHPVLEKLRSINNYNPKDFDWNP--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP---VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------NVKKE-------------------------RQGRVK----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Danio_rerio_YTHDF2_a ---MSASSLLE---QRPKGQ-----ANKVQ---NGAVTQKDTLNDDEFEPYLNAQPR------------------QSNAY TAMSDSYMPS------------YYSPSIGF-------TYSLNEAAWSTGGDPPMPYLASYGQLSNGEHHFLPDAM----- -----FGQSGALGNN-PFLGQHGFNFF----PSGIDFP--AWGNSSS----QGQST-----QSSGYSSSY-------AYA PSTLGGAMI-DGQSPFA--ANEPLNKAV--GMNSLDQGMAGLKIG------AGDMAPKVVGSGLPG-GPLSQVSTA---- ----PTMPPASMAP-----AKTASWADIASKPAKPQP-KLKTKGG---LGGTNLPPPPI---KHNMDIGTWDNKGNMPKP AAPQQ-------------T-SLPTNGQPPNQSSPQPGATAGGVPQLPLSNGQ--------------LVPPTGQLVQHPLP PGGQPGAVP---PQLSQGPP--AS------Q------------PSQPTRWVPPRNRANGFGD------------------ AAG-GPGQSPP-NSGMG--------------GIT-VPAEPHPVLEKLRMVNNYNPKDFDWNP--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSLANKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNTCAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLDKA-RQVLKIIASYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------SVKKVEVQG-----------------SDPYSNNSSRSHYRM QDRQGRVK------------------------------------------------------------------------ -------------------------------------------------------------------------------- --------------------- >Takifugu_rubripes_YTHDF2_a ---MSASSLLE---QRPKGQ-----ANKVQ---NGAVTQKDTLNDDEFEPYLSTQAR------------------QSNAY TAMSDSYMPS------------YYSPSVGF-------SYSLNEAAWSTGGDPPMPYLASYGQLSNGEPHYLPDAM----- -----FGQPGPLGSN-PFLNQHGFNFF----PGGIDFS--AWGNSSS----QGQSGTP---QSSGYSSSY-------AYA PSSLGGAMI-DGQSPFAPGANEPLNKAP--GMNSLDQGMAGLKLGGAAPGGNGDMAPKVVGSGLPGAGPLGPVSSVGT-- ----PSMPPVSIAT-----AKPASWADIASKPAKPQP-KLKTKGG---MAGANLPPPPI---KHNMDIGTWDNKGTMPKA AAPQQ-------------VPLNPSNGQPPIQVSPQPGATALGPHQLPPG------------------------------- ---QPGMVQIPQVPLSQGPP--PPS---QQQ------------APQPSRWVAPRNRANGFGD------------------ PSGNGAGQSPPTSSGVA--------------VLPGVPSEPHPVLEKLRMVNNYNPKDFDWNP--KQGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSLGAKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNTSAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLDKA-RQVLKIIAGYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------CVKKEPRIC-----------------AWRLEFGRS------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Takifugu_rubripes_YTHDF2_b ---MSASSLLE---QRPKGQ-----ANKVQ---NGAVTQKDTLNDDEFEPYLSTQAR------------------QSNAY TAMSDSYMPS------------YYSPSVGF-------SYSLNEAAWSTGGDPPMPYLASYGQLSNGEPHYLPDAM----- -----FGQPGPLGSN-PFLNQHGFNFF----PGGIDFS--AWGNSSS----QGQSGTP---QSSGYSSSY-------AYA PSSLGGAMI-DGQSPFAPGANEPLNKAP--GMNSLDQGMAGLKLGGAAPGGNGDMAPKVVGSGLPGAGPLGPVSSVGT-- ----PSMPPVSIAT-----AKPASWADIASKPAKPQP-KLKTKGG---MAGANLPPPPI---KHNMDIGTWDNKGTMPKA AAPQQ-------------VPLNPSNGQPPIQVSPQPGATALGPHQLPPG------------------------------- ---QPGMVQIPQVPLSQGPP--PPS---QQQ------------APQPSRWVAPRNRANGFGD------------------ PSGNGAGQSPPTSSGVA--------------VLPGVPSEPHPVLEKLRMVNNYNPKDFDWNP--KQGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSLGAKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNTSAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLDKA-RQVLKIIAGYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------CVKKYFKGG-----------------KYRYSHDCRADVSSV S------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gasterosteus_aculeatus_YTHDF2_b ---MSASSLLD---QRPKGQ-----ANKVQ---NGAVTQKDTLNDDEFEPYLNTQAR------------------QSNAY TAMSDSYMPS------------YYSPSIGF-------SYSLNEAAWSTGGDPPMPYLASYGQLSNGEPHYLPDAM----- -----FGQPGPLGNN-PFMGQHGFNFF----PSGIDFS--AWGNNTS----QGQSGTP---QSSGYSSSY-------AYA PSSLGGAMI-DGPSPFAPAANEPLNKAP--GMNSLDQGMAGLKIGGAAPGGNGDMAPKVVGSGLPGGGPHGPVTSVGP-- ----PSMPSVSIAP-----PKPASWADIASKPAKPQP-KLKTKGG---MAGANLPPPPI---KHNMDIGTWDNKGTMPKA ATPQQ-------------VPPIPSNGQPPNQASPQLASTAVGNPQMPLSNGQ--------------LGTPVSQMGQHQLL PGGQPGMG--QMPPLSQGPP--PS----QQQ------------PSQPTRWVAPRNRANGFGD------------------ GSGSGTGQSPLTSSGVG--------------VVPGVPSEPHPVLEKLRMVNNYNPKDFDWNP--KQGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDAAYRSLGAKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNTSAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLDKA-RQVLKIIAGYKHTTSIFDDFSHYEKRQEEEE------- ---------------------------------------CVKKVTK-------------------SQLNKVNGI------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Oryzias_latipes_YTHDF2_a ---MSASSLLE---QRPKGQ-----ANKVQ---NGPVTQKDTLNDDEFEPYLNSQARL-----------------QSNAY TAMSDSYMPS------------YYSPSIGF-------SYSLNEAAWSTGGDPPMPYLASYGQLSNGEPHYLPDAM----- -----FGQPGPLGSN-PFLSQHGFNFF----PSGIDFS--AWGNSSS----QGQSG------SSGYSSSY-------AYP PSSLGGAMI-DGQSPFAPAANEPINKAP--GMNSLDQGMAGLKIGGATPGGNGEMAPKVVGSGLPGGGPLGPVSSVGP-- ----TSMPPVSIAP-----VKPASWADIASKPAKPQP-KLKTKGG---MVGVNLPPPPI---KHNMDIGTWDNKGTMPKA ATPQQ-------------VPSVPTNGQPPSQASPQPGATAAGNPQMPLSNGQ--------------MVPPVSQMGQHQLP PTVQPGVAPMHQPPLSQGPP--PPPPSQQQQ------------PSQPNRWVPPRNRTNGFGD------------------ AGGSGTGHSPP-SSGVG--------------VVPGVPSEPHPVLEKLRMVNNYNPKDFDWNL--KHGRVFIIKSYSEDDI HRSIKYNIWCSTEHGNKRLDGAYRSLGGKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNTSAGVWSQDKWKGRFDVRWI FVKDVPNSQLRHIRLENNENKPVTNS----RDTQEVPLDKA-RQVLKIIAGYKHTTSIFDDFTHYEKRQEEEE------- ---------------------------------------CVKKVKTFC-----------------HQVEVQGS------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Anopheles_gambiae_YTHDF2 ---MPGNGDYNS-WSAQVNHG------------PGGVGHQKKSDDGYYRNHGAYQSHDS----------------VRNVE RGMQGLGLGSASRSGNSEGNS--------------GVSKYYQQQQQQKEAPKKMTWATIASQPAKPQVNTTSTTVK---- ------KKGPGMPPPPMIPGKHNMDIG---TWDSPSKNGPSVIVPTPPPIIPPPVI-----EPSPLADPVP--------S KSGGGRESVGGASSQHHGSNSQGMGPAGIQSSRWPTPGQAQIQQQQ--PSGTPSSSDRNNGPSAGTNSGSGGSGSNAASG GSMPSGSQHHNQHHQHQQGSHTRNHSSPYQPPQQQQP-HHADRPG-SNYDRAPHHQHQQGGLQHGNSYNQSRNQNAAYSP SGPG----------------------GLAATGPSSAMADRQNSGGSGGD------------------------------- NYRPPHDGRSGPQQHNSMHHHQQTERAPFHHQQRPSNHHGDRVSGGSSYQPADRGHYGSNSSSDA--------------- VSHNSSSTVPPVTTAPAAVKARSPSPTISESEMALKLAESQKILDQLKTKNNYNPASLDLLKTVDLARFFVIKSYSEDDI HRSIKYEIWCSTEHGNQRLDQAFREREEKGGT--VYLFFSVNGSGHFCGVAQMMTAVDYNSNSSVWSQDKWKGTFKVRWI YVKDVPNSHLRHIRLENNENKSMTNS----RDTQEVPNAKG-IQVLQIIHSFEHQSSIFDDFQHYEKRQMEEDTRKHEAP PPSNHSYHNQRDRRENQGGGNYYDGPGKYHGGGGGGGGYNNKYNDRGGDDGYDGGYGSRGGGGGYHGGYNKGGSSGGYGG YNNRNSYNNRDDPGRGYPSFDRRNNNGNSGGSNNNGDDQHDAAAPGGGGGGGYNSRGGYNNRSRDYYRDERRGPNDYGRA RGSDFDNGRDSDGGGIYRSGDRGDRGDRGDRGERGERGDRGDRGDRGDRGDRGDRGDRGDRDRGSSRDHFRDRNDRMMGP GNNRGGSGSNGSGSNIFRNPN >Homo_sapiens_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNS--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQPQQ-------------QQLQNRWVAPRNRGAGFNQNNG--------------A GSENFGLGVVPVSASP-------------------SSVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gorilla_gorilla_YTHDF3 ---------------------------------------------------------Q------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNS--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQPQQ-------------QQLQNRWVAPRNRGAGFNQNNG--------------A GSENFGLGVVPVSASP-------------------SSVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ETNYLRNNS-- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Pongo_abelii_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMS---------------- -------------------------------------------------------------------------------- -----------------------LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNS--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIEQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQPQQ-------------QQLQNRWVAPRNRGAGFNQNNG--------------A GSENFGLGVVPVSASP-------------------SSVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Mus_musculus_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQKYRRAKQL-------FHCNNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QNSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNN--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQSQQ-------------PQLQNRWVAPRNRGTGFNQNNG--------------T GSENFGLGVVPVSASP-------------------SSVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Rattus_norvegicus_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------NNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QNSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNN--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGSVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQSQQ-------------PQLQNRWVAPRNRGTGFNQNNG--------------T GSENFGLGVVPVSASP-------------------SSVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Canis_familiaris_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GISSIEQGMTGLKIGG--DLTAA--VTKTVGTALS-SSGMTSIATNS--- ----VPP--VSSAA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GSAVPPPPI---KHNMNIGTWDEKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQPQQ-------------QQLQNRWVAPRNRGAGFNQNNG--------------V GGENFGLGVVPVSASP-------------------SNVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ESETNSF---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Monodelphis_domestica_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIT-DGQAGFG--NDT-LSKVP--GINSIEQGMTGLKIGG--DMTAA--VTKTVGSALS-STGMTSIAANS--- ----VPP--VSSSA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GPAVPPPPI---KHNMNIGTWDDKGSVVKA PPT-------------------------QPVLPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQPQQQQGPQPQAQPHQVQQQQP------------QQLQNRWVAPRNRGVGFNQNNG--------------A GSENFGLGVVPVSSSP-------------------SGVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gallus_gallus_YTHDF3 ---FSLLSYVQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIA-DGQAGFG--SDT-LSKVP--GISSIEQGMTGLKIGG--DMTAA--VTKTVGSALS-STGMTSIAANS--- ----VPP--VSSSA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GPAVPPPPI---KHNMNIGTWDDKGSVVKA PPA-------------------------QPVLPPQTIIQQPQPLIQP--------------------PTLVQSQLP---- --QQQPQPQQPQQQQGPQQQAQPHQLQQQQ---------------LQNRWVAPRNRGVGFSQNNG--------------A GSENFGLGVVSVSSSP-------------------SGVEVHPVLEKLKAINNYNP-DFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---L-LLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------VRNQYYS---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Pelodiscus_sinensis_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVS-VQNGSIHQKDAVNDDDFEPYLSSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLSEAAWSTAGDPPMPYLTTYGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIA-DGQAGFG--NDT-LSKVP--GINSIEQGMTGLKIGG--DMTAA--VTKTVGSALS-STGMTSIAANS--- ----VPP--VSSSA-----PKPTSWAAIARKPAKPQP-KLKPKGNVGIG-GPAIPPPPI---KHNMNIGTWDDKGSVVKA PPS-------------------------QPILPPQTIIQQPQPLIQP--------------------PPLVQSQLP---- --QQQPQPPQ--QQQGPQQQAQNHQLQQQQ-------------QQLQNRWVAPRNRGVGFSQNNGG-------------S GSENFGLGVVPVSSSP-------------------SGVEVHPVLEKLKAINNYNPKDFDWNL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFDVKWI FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Xenopus_tropicalis_YTHDF3 ---MSATSVDQ----RPKGQ-----GNKVA-VQNGSMHQKDAVNDDDFEPYLNSQTNQ------------------SNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYL--YGQMSNGEHHYIPDGV----- -----FSQPGALGNTPPFLSQHGFNFF----PGNADFS--TWGTSGS----QGQST-----QSSAYSSSY-------GYP PSSLGRAIA-DGQAGFG--SDA-LSKVP--GINSIEQGMTGLKIGG--DMTAA--VTKTVGSALS-SAGMTSIAANS--- ----VPP--VSSSA-----PKPTSWAAIARKPAKPQP-KLKPKNNVGIG-SSAVPPPPI---KHNINIGTWDDKGAIVKT PPI-------------------------QSVLPPQPVIQQPQPLTQP--------------------LPMVQNQLP---- --QQQLQ------QQGPQQ--PPHQIQQQL----------------QNRWVAPRNRGAGFNQNNV--------------S GNENFSLGVVPVSSSP-------------------SGVEVHPVLEKLKAINNYNPKDFDWSL--KNGRVFIIKSYSEDDI HRSIKYTIWCSTEHGNKRLDAAYRSLNGKGP---LYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFDVKWV FVKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATFKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------AMRR--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Takifugu_rubripes_YTHDF3_a ---MSATTVDQ----RPKGQ-----GNKAP-VQNGSMHQKDGVNDDDFEPYISGQTNQ------------------NNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYLTTYGQMSNGEPHFIPDGL----- -----FSQPGALGNTPPFLGQHGFNFF----PGNADFS--TWGTSVS----QGQST-----QSSVYSNSY-------GYA PSSLGRAIA-DGQAGFG--SDTQLSKVP--VLNSIEQGMTGLKLGT--EMVSA--VTKTVGSPIGGTAGMSSLATNS--- ----LPPS-VSSST-----PKPASWAAIAKKPAKLQP-KVKPKANMGMVGGATIPPPPI---KHNFNIGTWDDKGSLNKP PLA-------------------------QTMLPPQPLVQQP-LLAQH--------------------QPLLQNPLP---H QP--QHQHQHQHQPQPPGPP--LHHQHPQQP------------GPPPNRWVAPRNRGEGFCLGGG--------------- ---------VPLSASL-------------------CSGELHPMLEKLQALNNYNPKDFDWSL--KNGRIFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAYRSLGNKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNAYAGVWSQDKWKGKFEVKWI FIKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------ILRK--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Tetraodon_nigroviridis_YTHDF3_a ---MSATTVDQ----RPKGQ-----GNKAP-VQNGSMHQKDGVNDDDFEPYISGQTNQ------------------NSSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYLTTYGQMSNGEPHFIPDGV----- -----FGQPGTLGNTPPFLGQHGFNFF----PGNADFS--TWGTSVS----QGQST-----QSSVYSNSY-------GYA PSSLGRAIA-DGQAGFG--SDSQLSKVP--VLNSIEQGMAGLKLGT--EMVSA--VTKTVGSPVGGTAGMSSLAASG--- ----LPPS-ISSSA-----PKPASWAAIAKKPAKLQP-KVKPKANM--VGGAAIPPPPI---KHNLNIGTWDDKGSLNKP PLA-------------------------QTMLPPQPLVQQP-LLAQH--------------------QPLLQNPLP---H HHSLPPGPPHLQLSSQAGPP--LHQQHPQQA------------GPPPNRWVAPRNRGEGFCLGGG--------------- ---------VPLSASP-------------------CSGEVHPVLEKLQALNNYNPKDFDWSL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAYHSLGSKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNAFAGVWSQDKWKGKFEVKWI FIKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLRIIATYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------VLRK--------------------------ERNRNKQ---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------- >Gasterosteus_aculeatus_YTHDF3_a ---MSATTVDQ----RPKGQ-----GNK---VQNGSMHQKDGVNDDDFEPYLSGQTNQ------------------GNSY PPMSDPYMPS------------YYAPSIGF-------PYSLGEAAWSTAGDPPMPYLTTYGQMSNGEPHFIPDGV----- -----FSQAGALGNTPPFLGQHGFNFF----PGNADYS--TWGTSVS----QGQST-----QSSVYSNSY-------GYA PSSLGRAIT-DGQAGFG--SDTQLSKVP--VLNSIEQGMTGLKLGT--DMVAA--VTKTVGSPLGGTAGMSSMAANS--- ----LPPS-VNSSA-----PKPASWAAIAKKPAKPQP-KVKPKANMGLG-GGAIPPPPI---KHNMNIGTWDEKGSLNKP PLA-------------------------QNMMPPQPMVQQP-LLAQP------PALTAKPHCLLRLHQPFQLHSLQSPQH PQPMPPGHPHMHLSSQPGPPQHLHQQPPQQP------------GPPPNRWVAPRNRGEGFGLGGG--------------- ---------LPLSASP-------------------CSGEVHPVLEKLRALNNYNPKDFDWSL--KNGRVFIIKSYSEDDI HRSIKYSIWCSTEHGNKRLDGAYRSLGNKGP---LYLLFSVNGSGHFCGVAEMRSPVDYNAYAGVWSQDKWKGKFEVKWA FIKDVPNNQLRHIRLENNDNKPVTNS----RDTQEVPLEKA-KQVLKIIATYKHTTSIFDDFAHYEKRQEEEE------- ---------------------------------------ALRK--------------------------ERNRNKP---- -------------------------------------------------------------------------------- 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