>Homo_sapiens_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGQEEE LLRIAKKLEKMVAR-KNTEG------------------------------------------------------------ ------------ALDLLKKLHSCQ--MSIQLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PGPPKGEK GEERE--------------------KAKKKEKGLEC-SDWKPEAGLSPPRKKR-EDPKT-----------RRDSVDSKSS -----------------ASSSPKRPSV----------ERSNSSKS-----------KAES---PKTPSSPLTPTF----- --------ASSM------CLLAPCYLTGDSVRDKCVEMLSAALKADD---DY--KDYGVNCDKMASEIED---------- -HIYQELK----STDMK----YRNRVRSRISNLKDPRN--------PGLRRNVLSGAISAGLIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLFQCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Pan_troglodytes_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGQEEE LLRIAKKLEKMVAR-KNTEG------------------------------------------------------------ ------------ALDLLKKLHSCQ--MSIQLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PGPPKGEK GEERE--------------------KAKKKEKGLEC-SDWKPEAGLSPPRKKR-EDPKT-----------RRDSVDSKSS -----------------ASSSPKRPSV----------ERSNSSKS-----------KAES---PKTPSSPLTPTF----- --------ASSM------CLLAPCYLTGDSVRDKCVEMLSAALKADD---DY--KDYGVNCDKMASEIED---------- -HIYQELK----STDMK----YRNRVRSRISNLKDPRN--------PGLRRNVLSGAISAGLIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLFQCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Mus_musculus_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGLEEE LLRIAKKLEKMVSR-KKTEG------------------------------------------------------------ ------------ALDLLKKLNSCQ--MSIQLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PRTTKGER -EERE--------------------KAKK-EKGLGC-SDWKPEAGLSPPRKKGGGEPKT-----------RRDSVDSRSS -----------------TTSSPKRPSL----------ERSNSSKS-----------KVET---PTTPSSPSTPTF----- --------APAV------CLLAPCYLTGDSVRDKCVEMLSAALKAED---NF--KDYGVNCDKLASEIED---------- -HIYQELK----STDMK----YRNRVRSRISNLKDPRN--------PGLRRNVLSGAISPELIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLLRCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Rattus_norvegicus_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGLEEE LLRIAKKLEKMVAR-KKTEG------------------------------------------------------------ ------------ALDLLKKLNSCQ--MSIQLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PRTTKGER -EARE--------------------KAKKKEKGLGS-SGWKPEAGLSPPRKKEGGEPKT-----------RRDSVDSRSS -----------------TTSSPKRPSL----------ERSNSSRS-----------KVET---PKTPSSPSTPTF----- --------APAV------CLLASCYLTGDSVRDKCVEMLSAALKAED---DF--KDYGVNCDKLASEIED---------- -HIYQELK----STDMK----YRNRVRSRISNLKDPRN--------PGLRRNVLSGTISPELIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLLRCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Canis_familiaris_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGQEEE LLRIARKLEKMVAR-KNSEG------------------------------------------------------------ ------------ALGLLKKLNSCQ--MSIQLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PGPPKGEK GEERD--------------------KAKK-EKGLDC-SNWKPETGLSPPRKKRAEEPKE-----------RRDSVDSKSS -----------------ATSSPKRPSM----------ERSNSGKS-----------KAET---PKTPTSPSTPTF----- --------APSV------CLLAPCYLTGDSVRDKCVEMLSAALKAED---DY--KDYGVNCDKMASEIED---------- -HILEELK----STDMK----YRNRVRSRISNLKDPRN--------PSLRRNVLSGAISAGLIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLFQCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKVC---------------------------------------------------------------------------- ----------- >Felis_catus_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGQEEE LLRIARKLEKMVAR-KNTEG------------------------------------------------------------ ------------ALDLLKKLDSCQ--MSIRLLQTTRIGVAVNGVRKHCSDK-EVVSLAKVLIKNWKRLLDS-PGPPKGEK REERD--------------------KAKK-EKGLNC-SDWKPEAGLSPPRKKR-EDPKD-----------RRDSVDSKSS -----------------ATSSPKRPSM----------ERSNSSKS-----------KAET---PKTPTSPSTPTF----- --------APSI------CLLAPCYLTGDSVRDKCVEMLSAALKAED---DY--KDYGVNCDKMASEIED---------- -HILEELK----STDMK----YRNRVRSRISNLKDPRN--------PSLRRNVLSGAISAGLIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTDLFQCSKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKVC---------------------------------------------------------------------------- ----------- >Myotis_lucifugus_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGREEE LLRIAKKLEKMVAR-KHTEG------------------------------------------------------------ ------------ALDLLKKLNSCQ--MSIQLLQTTRIGVAVNGVRKYCSDK-EVVSLAKVLIKKWKRLLDS-PESPKGGK EEERE--------------------KAKKKEKELDC-SNWKSEAGLSPPRTKQGEEPKD-----------RRDSVDSKSS S----------------ATSSPKRPSM----------ERSNSGKS-----------KAETS--PKTPSSPSSPTF----- --------ASSI------CLLAPCYLTGDSVRDKCVEMLSAALKADD---DY--KDYGVNCDKMASEIED---------- -HILEELK----STDMK----YRNRVRSRISNLKDPRN--------PGLRRNVLSGAISTGLIAKMTAEEMAS------D ELRELRNAMTQEAIREHQMAKTG-GTTTGLFQCKKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKVC---------------------------------------------------------------------------- ----------- >Monodelphis_domestica_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGQEEE LLRIAKKLDKMVSR-KNTEG------------------------------------------------------------ ------------ALDLLKKLSDYK--MSIQLLQTTRIGIAVNGVRKHCLDK-EVVALAKILIKNWKRLLDT-SETPKKEK AMERE--------------------KEKKKEQNVDL-SDWKPLEAFSPQSRSPREEPKD-----------RRDSSESGSS SSVV-------------SSPSPQKRPV----------ERSNSSKG-----------KVET---PKTPTSPSSPTF----- --------SPSA------CCLAPCYLTGDSVRDKCVEMLSAALKMDD---DY--KEYGVNCDKMASEIED---------- -HIFQELK----GTDMK----YRNRVRSRISNLKDPRN--------PNLRRNVLCGAISTSLIARMTAEEMAS------D ELKELRNAMTLEAIREHQMAKTG-GTTTDLFQCISVKRRIVP----------IT-RCRQEVLMSP--------------- -------------------------------------------------------------------------------- ----------- >Taeniopygia_guttata_TCEA3 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGPAEE LVRIAKKLDKMVAR-KSTEG------------------------------------------------------------ ------------ALDLLKSLTGYT--MTIQLLQTTRIGVAVNSVRKHCSDE-EVVASAKILIKNWKRLLGD-PNAFWGDR EKDTD---------------------GDKEKKGLDV-SSCPTTSGTAPGQFLKEGEPLT-----------GRASADSRSS -----------------TLSSSSSSQK----------RLANSSNV-----------KTEV------PRSPTSPSF----- --------SPSP------CFLAPCYLTGDSVRDKCIEMLTAALRMDD---DY--KEFGVNCEKMASEIED---------- -HILGLG-----STDMK----YRNRVRSRISNLKDPKN--------PALRRNVLCGAIEPSLIARMTAEEMAS------D ELKKLRNAMTQEAIREHQMAKTG-GTVTDLFQCGKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKVC---------------------------------------------------------------------------- ----------- >Takifugu_rubripes_TCEA3_a -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTREEE LVRIAKQLDKMVSR-NNTDG------------------------------------------------------------ ------------AMDLLRELKSFN--MTLRLLQETRIGVSVNSIRKHCTDE-EVIALAKVLIKDWKRLLETGHQTKNRLR F----------------------------REKAVHQKRRESSDSKPGPPLKRNSTESKP----------ERRESQGSR-- ------------------SSQPGPPQ------------RKPSTD------------GNERKAKPDTPKSPTTPTS----- --------PMSP-----GGALPPHLNTGDSVRDKCIEMLAAALRTDIYTDDY--KEFGTNCDSMAAEIEDH--------- -HIYQEIK----ATDMK----YKNRVRSRISNLKDPKN--------PGLRKNVLAGTLALSRIASMSAEEMAS------D ELKQLRNTLTQEAIREHQMAKTG-GTSTDLLQCGKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Takifugu_rubripes_TCEA3_b -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTREEE LVRIAKQLDKMVSR-NNTDG------------------------------------------------------------ ------------AMDLLRELKSFN--MTLRLLQETRIGVSVNSIRKHCTDE-EVIALAKVLIKDWKRLLAS--------- ----------------------------------------------------PSSSKFF----------SRRESQGSR-- ------------------SSQPGPPQ------------RKPSTD------------GNERKAKPDTPKSPTTPTS----- --------PMSP-----GGALPPHLNTGDSVRDKCIEMLAAALRTDIYTDDY--KEFGTNCDSMAAEIED---------- -HIYQEIK----ATDMK----YKNRVRSRISNLKDPKN--------PGLRKNVLAGTLALSRIASMSAEEMAS------D ELKQLRNTLTQEAIREHQMAKTG-GTSTDLLQCGKCKKKNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Tetraodon_nigroviridis_TCEA3_b -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTREEE LVRIAKKLDKMVSR-NTTDG------------------------------------------------------------ ------------AMDLLRELKSFN--MTLKLLQETRIGVSVNSIRKHCADE-EVIALAKVLIKDWKRLLGSGRRPYAEKP AGLKNGLDPARAAAASPGSSPPDTQNRRDEKDSSSHPHPHAPPPSSPPPAKRPSLEARK----------ERRDSSSGRGS AKPSDDAQKRDRRES--VDSKAGPPPKRNSTGS--KPERRESSDSKKSSSSPAKKLTAERRPKADTPKTPTTPTS----- --------PTSP-----GGLLPPHLSTGESVRDKCIEMLAAALRTDN---DY--KEFGTNCDSMAAEIED---------- -HILLEIK----ATDMK----YKNRVRSRISNLKDPKN--------PGLRKNVLAGTIALSRIASMSAEEMAS------D ELKQLRNTLTQEAIREHQMAKTG-GTTTDLLQCGKCKKKNCT----------YNQQVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Gasterosteus_aculeatus_TCEA3_a -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTREED LTRIAKKLDKMVSR-NNTEG------------------------------------------------------------ ------------ALDLLRELKSFN--MTLKLLQETRIGMSVNGIRKNSTDE-EVIALAKLLIKDWKRLLDLEKAAERNNG LD------------------SSKTAVSPKGPPSETHSRKDSCDSKPGQPVRHKSTDSKP----------GRRESTDSKKS SSPPAKKLTVERESQGLKTSQPGPPQ------------RKPSTD------------IMERKGKADTPKTPTSPTS----- --------PMSPSGSSSGGPVPPHLATGDSVRDKCIYMLAAALRTDD---HY--KDFGTNCDSMAAEIED---------- -YIYQETK----ATDMK----YKNRVRSRISNLKDPKN--------PGLRRNVLAGSIDLSRIASMSAQEMAS------D ELKQLRNVLTQEAIREHQMAKTG-GTSTDLLQCGKCKKRNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Gasterosteus_aculeatus_TCEA3_b -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTREED LTRIAKKLDKMVSR-NNTEG------------------------------------------------------------ ------------ALDLLRELKSFN--MTLKLLQETRIGMSVNGIRKNSTDE-EVIALAKLLIKDWKRLLVSHRR------ ------------------------------------------------LHVKLKHDSSP----------EKKQPDKSG-- ------------------KEKHNEER------------RARRAD-----------------DPSDDEKHLEEPGR----- --------TESS-----DSKPPPQKKMPDPVK---IKQMFPFVRKDS--SDS--KPPLLKKPSLGVKKEK---------- -HRCNETK----ATDMK----YKNRVRSRISNLKDPKN--------PGLRRNVLAGSIDLSRIASMSAQEMAS------D ELKQLRNVLTQEAIREHQMAKTG-GTSTDLLQCGKCKKRNCT----------YN-QVQTRSADEPMTT--FVLCNECGNR WKFS---------------------------------------------------------------------------- ----------- >Homo_sapiens_TCEA1 -------------------------------------------------------------------------------- ----------------------------------------------------------------------------MEDE VVRFAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTE-KDLDEKKKEPAIT-----------SQNSPEAREE S---------------------------------------------------------------TSSGNVSNRKD----- --------ETNAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--IAIGADEEELGSQIEEA--------- --IYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Macaca_mulatta_TCEA1 -------------------------------------------------------------------------------- ----------------------------------------------------------------------------MEDE VVRFAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTE-KDLDEKKKEPAIT-----------SQNSPEAREE S---------------------------------------------------------------TSSGNVSNRKD----- --------ETNAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--IAIGADEEELGSQIEEA--------- --IYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Mus_musculus_TCEA1 -------------------------------------------------------------------------------- ----------------------------------------------------------------------------MEDE VVRIAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNALRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDPEEKKKEPAIS-----------SQNSPEAREE S---------------------------------------------------------------SSSSNVSSRKD----- --------ETNAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--VAIGADEEELGSQIEEA--------- --IYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Rattus_norvegicus_TCEA1 -------------------------------------------------------------------------------- ----------------------------------------------------------------------------MEDE VVRIAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDSEEKKKEPAIS-----------SQNSPEAREE S---------------------------------------------------------------SSSSHVSSRKD----- --------ETNAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--VAIGADEEELGSQIEEA--------- --IYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Felis_catus_TCEA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------G------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDPEEKKKDTAVT-----------SQNSPEAREE RQNKKQDSSIRLTKLS--------------------------------LDAKGSKNKSPLKPRRNSSGNISSRKE----- --------EANAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--VAIGADEEELGSQIEEDILSVYIHDL VPIYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKSVFC-------------------------------------------------------------------------- ----------- >Bos_taurus_TCEA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------AG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDSEEKKKDTAVT-----------SQNSPEAREE S---------------------------------------------------------------SSSGNMSSRKD----- --------ETNAR-DTYVSSFPRAPSTSDSVRLKCREMLAAALRTGD---DY--IAIGADEEELGSQIEEA--------- --IYQEIR----NTDMK----YKNRVRSRISNLKDAKN--------PNLRKNVLCGNIPPDLFARMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Monodelphis_domestica_TCEA1 -------------------------------------------------------------------------------- ----------------------------------------------------------------------------MEDE IIRIAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDSDEKKKEPAIS-----------SQNSPEAKEE S---------------------------------------------------------------SSSSNASNRKE----- --------ETNAS-DSFIPSFPRAPSTSDSVRMKCREMLAAALRTGD---DY--IAIGADEEELGSQIEEA--------- --IYQELR----NTDMK----YKNRVRSRIANLKDAKN--------PNLRKNVLCGNIPPDLFARLTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Gallus_gallus_TCEA1 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MTTEDE IIRIAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQTTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSTD-KDSEEKKKEPASS-----------SQNSPEAREE S---------------------------------------------------------------SSSSNSSSRKE----- --------EGSAPSNSFIPSFPRAPSTSDSVRVKCREMLSAALRTGD---DY--IAIGADEEELGSQIEEA--------- --IFQELK----NTDMK----YKNRVRSRIANLKDAKN--------PNLRKNVLCGNIPPDKFAKMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Anolis_carolinensis_TCEA1 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MSAEDE IIRIAKKMDKMVQK-KNAAG------------------------------------------------------------ ------------ALDLLKELKNMP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PSND-KDSEDKKKEAASS-----------SQNSPEAREE S---------------------------------------------------------------SSSSNSSNRKE----- --------ESNTGSDAFISSFPRAPITSDSVRMKCREMLAAALKTGD---DY--IAIGADEEELGSQIEEAP-------- --IFQELK----NTDMK----YKNRVRSRIANLKDTKN--------PNLRKNVLCGNIAPDRFAKMTAEEMAS------D ELKEMRKNLTKEAIREHQMAKTG-GTQTDLFSCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Xenopus_tropicalis_TCEA1 -------------------------------------------------------------------------------- ------------------------------------------------------------------------MSSAAGDE IIHIAKKMERMVQK-KNTAG------------------------------------------------------------ ------------ALDLLKELKNLP--MTLELLQSTRIGMSVNAIRKQSGEE-EVTSLAKSLIKSWKKLLDG--------- -----------------------------------------PS---ADMEEKRKDQPAP-----------AQNSPEAREE S---------------------------------------------------------------SSSTNISARKE----- --------ECPAPSDGFITSFPRAPSTSDSVRIKCRELLATALKTGD---DH--IAIGADVDELGAQIEEA--------- --VFQEFK----NTEAK----YKNRIRSRIANLKDAKN--------PNLRRNVLCGNIAPDLFARMSAEEMAS------D ELKEMRKNLTKEAIREHQMARTG-GTETDLFTCGKCKKKNCT-----------YTQVQTRSADEPMTT--FVFCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Danio_rerio_TCEA1_a -------------------------------------------------------------------------------- ------------------------------------------------------------------------MGKKEEEE IIRIAKKMDKMAQK-KNGVG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDD-EVTSLAKSLIKSWKKLLDE--------- -----------------------------------------PAAD-KNSEEKKKERTTPV-------VSPSETSPEPREE S----------------------------------------------------------------SSSNSSSKSE----- --------SVDVTPNTLIATFPRAPGTSDSVRIKCREMLSNALQTGD---DY--ITIGSDCDELGAQIEECIFL------ -----EFK----NTDMK----YKNRVRSRISNLKDAKN--------PNLRRNVLCGNVSPDRIAKMTAEEMAS------D ELKEMRKNLTKEAIRDHQVATSG-GTQTDLFTCGKCKKKKCT-----------YTQVQTRSADEPMTT--FVFCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Danio_rerio_TCEA1_b -------------------------------------------------------------------------------- ------------------------------------------------------------------------MGKKEEEE IIRIAKKMDKMAQK-KNGVG------------------------------------------------------------ ------------ALDLLKELKNIP--MTLELLQSTRIGMSVNAIRKQSTDD-EVTSLAKSLIKSWKKLLDE--------- -----------------------------------------PAAD-KNSEEKKKERTTPV-------VSPSETSPEPREE S----------------------------------------------------------------SSSNSSSKSE----- --------SVDVTPNTLIATFPRAPGTSDSVRIKCREMLSNALQTG----DY--ITIGSDCDELGAQIEEYILFIF---- ---MPNFK----NTDMK----YKNRVRSRISNLKDAKN--------PNLRRNVLCGNVSPDRIAKMTAEEMAS------D ELKEMRKNLTKEAIRDHQVATSG-GTQTDLFTCGKCKKKKCT-----------YTQVQTRSADEPMTT--FVFCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Takifugu_rubripes_TCEA1_a -------------------------------------------------------------------------------- ------------------------------------------------------------------------MGKKEEED IIRIAKKIDKMAQK-KNGAG------------------------------------------------------------ ------------ALDLLKELRSIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDE--------- -----------------------------------------PGGGEKTSEEKRKEQSTPV-------ISSSQESPEAREE SS--------------------------------------------------------------CSSSNNNSRSE----- --------PSDDTPSSFVNTFPRAASTSDPIRVKCREMLANALQTGD---DY--IAIGADCDELGAQIED-YILS----- -----MFK----NTDMK----YKNRVRSRISNLKDVKN--------PNLRRTVLCGSITPERMAKMTAEEMAS------D ELKEIRKNLTKEAVRDHQMATTG-GTQTDLFTCGKCKGKNCT-----------YTQVQTRSADEPMTT--FVFCSGCGNR WKVC---------------------------------------------------------------------------- ----------- >Takifugu_rubripes_TCEA1_b -------------------------------------------------------------------------------- ----------------------------------------------------------------------VKMGKKEEED IIRIAKKIDKMAQK-KNGAG------------------------------------------------------------ ------------ALDLLKELRSIP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLL----------- --------------------------------------------------VIKKERSECP-------RSDFSASPSFRS- ----------------------------------------------------------------CSSSNNNSRSE----- --------PSDDTPSSFVNTFPRAASTSDPIRVKCREMLANALQTGD---DY--IAIGADCDELGAQIED-YILS----- -----MFK----NTDMK----YKNRVRSRISNLKDVKN--------PNLRRTVLCGSITPERMAKMTAEEMAS------D ELKEIRKNLTKEAVRDHQMATTG-GTQTDLFTCGKCKGKNCT-----------YTQVQTRSADEPMTT--FVFCSGCGNR WKVC---------------------------------------------------------------------------- ----------- >Tetraodon_nigroviridis_TCEA1_a -------------------------------------------------------------------------------- ------------------------------------------------------------------------MGKKEEEE IIRIAKKIDKMAQK-KNGSG------------------------------------------------------------ ------------ALDLLKELRSVP--MTLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLDE--------- -----------------------------------------PGSGEKTSEEKRKEQSTPI-------ISSSQESPDAREE S---------------------------------------------------------------CSSSNTNSRSE----- --------PLDDTPGSFVNAFPRAASTSDPIRVKCREMLANALQTGD---DY--IAIGADCDELGAQIED-FIFQ----- -----EFK----NTDMK----YKNRVRSRISNLKDVKN--------PNLRRTVLCGSITPERMAKMTAEEMAS------D ELKEIRKNLTKEAVRDHQMATTG-GTQTDLFTCGKCKGKNCT-----------YTQVQTRSADEPMTT--FVFCNGCGNR WKIC---------------------------------------------------------------------------- ----------- >Gasterosteus_aculeatus_TCEA1_a -------------------------------------------------------------------------------- ------------------------------------------------------------------------MGKKEEDE IIRIAKKMDKMAQK-KNGAG------------------------------------------------------------ ------------ALDLLKELRSIP--MTLELLQSTRIGMSVNAIRKQSTDD-EVTSLAKALIKSWKKLLDE--------- -----------------------------------------PGSGEKPSDEKRKEPTTP--------VSPSQGSPEAKEE S---------------------------------------------------------------SSSSNSSSKSE----- --------PAEVSTNSLINTFPRAPRTSDSIRIKCRELLAAALQAGD---DH--IAIGADCDELGAQIEE-VIFQ----- -----EFK----NTDPK----YKSRVRSRISNLKDMKN--------PNLRRTVLCGSVTPERMAKMTAEEMAS------D ELKEMRKNLTKEAVRDHQMATTG-GTQTDLFTCGKCKGKCCT-----------YTQVQTRSADEPMTT--FVFCNDCGNR WKFC---------------------------------------------------------------------------- ----------- >Oryzias_latipes_TCEA1_a -------------------------------------------------------------------------------- ------------------------------------------------------------------------MSKKEEEE IIRIAKKMDKMAQK-KNGAG------------------------------------------------------------ ------------ALDLLKELRNIP--MSLELLQSTRIGMSVNAIRKQSTDE-EVTSLAKSLIKSWKKLLGS--------- -----------------------------------------PCPDIKKKAQKHQE-QKPV-------CSLSIHSLKNRTT S----------------------------------------------------------------SSSNFSSRSD----- --------TTEVAPNSLIHNFPRAPSTSDSIRLKCREMLANALQTGE---DY--IAIGADCEELGAQIEE-YILH----- -----EFK----NTDMK----YKNRVRSRISNLKDMKN--------PNLRRTVLCGSVSPERMAKMTAEEMAS------D ELKEMRKNLTKEAVRDHQMATTG-GTQTDLFTCGKCKGKCCT-----------YTQVQTRSADEPMTT--FVFCNQCGNR WKVC---------------------------------------------------------------------------- ----------- >Branchiostoma_floridae_TCEA1 MENALDILKSLKELPMTLDILQKTRIGMSVNNLRKSSNSEEVNSLAKSLIKSWKKLLNQNGAPKRSDSTSSEPSEKSPPE GTKLQRQDSSSTAGSSFSSSQDSFPAVTKTHDSVREKCREMLANALKTDEFKNTEMKYKTRVRSRIANLKDAKNPGLREK VLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEAIRDAQMATTGGTQTDLLKCGKCKKRNVTYNQVQTRSADEPMTTFC YCNECGNRWKENALDILKSLKELP--MTLDILQKTRIGMSVNNLRKSSNSE-EVNSLAKSLIKSWKKLLN---------- ------------------------------------------QNG-APKRSDSTSSEPS-----------EKSPPEGTKL Q---------------------------------------------------------------RQDSSSTAGSS----- --------FSSS----QDS-FPAVTKTHDSVREKCREMLANALKT----------------------------------- ----DEFK----NTEMK----YKTRVRSRIANLKDAKN--------PGLREKVLHGDVSAEKMAKMTAEEMAS------P EMKELRQSLTKEAIRDAQMATTG-GTQTDLLKCGKCKKRNVT-----------YNQVQTRSADEPMTT--FCYCNECGNR WKATKTLRCRCIRIITPPCMIYHNAVIISSRTVVATAPEGSIRPKSSLSSDATASADRLSGAEIRRDAGGIACLAQVPRA QTAGVATATGG >Saccoglossus_kowalevskii_TCEA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------MPGTEEE VIRIGKQLEKMVSKNASDLG------------------------------------------------------------ -----------NAFDLLKSLKELP--MTLEVLQKTRIGMSVNSLRKQSSNE-EVISLAKSLIKSWKKLLP---------- ------------------------------------------APS-SSKSSNKDNQDSS-----------RDSPTDLSQD G---------------------------------------------------------------NSINSNNDNSS----- --------SSQS----KSSSKFQVPKTNDAVREKCREMLTNALKTPLGDIESVGTEELGEPEEIAATIEDC--------- --IFTEFT----NTEAK----YKTRVRSRVANLKDVRN--------PILRQQVLCGSIPPEKIANMTAEEMAS------D RLKELRRELTKEAIREAQMSTTG-GTKTSLLKCGKCKKRNCT-----------YNQVQTRSADEPMTT--FVFCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Homo_sapiens_TCEA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------MMGKEEE IARIARRLDKMVTK-KSAEG------------------------------------------------------------ ------------AMDLLRELKAMP--ITLHLLQSTRVGMSVNALRKQSSDE-EVIALAKSLIKSWKKLL----------- ------------------------------------------DASDAKARERGRGMPLP-----------TSS-RDASEA PDP--------------------------------------------------------------SRKRPELPRA----- --------PSTP----RITTFPPVPVTCDAVRNKCREMLTAALQTDH---DH--VAIGADCERLSAQIEEC--------- --IFRDVG----NTDMK----YKNRVRSRISNLKDAKN--------PDLRRNVLCGAITPQQIAVMTSEEMAS------D ELKEIRKAMTKEAIREHQMARTG-GTQTDLFTCGKCRKKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Gorilla_gorilla_TCEA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------MMGKEEE IARIARRLDKMVTK-KSAEG------------------------------------------------------------ ------------AMDLLRELKAMP--ITLHLLQSTRVGMSVNALRKQSSDE-EVIALAKSLIKSWKKLL----------- ------------------------------------------DASDAKARERGRGTPLP-----------TSS-RDASEA PDP--------------------------------------------------------------SRKRPELPRA----- --------PSTP----RITTFPPVPVTCDAVRNKCREMLTAALQTDH---DH--VAIGADCERLSAQIEEC--------- --IFRDVG----NTDMK----YKNRVRSRISNLKDAKN--------PDLRRNVLCGAITPQQIAVMTSEEMAS------D ELKEIRKAMTKEAIREHQMARTG-GTQTDLFTCGKCRKKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Mus_musculus_TCEA2 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGKEEE IARIARRLDKMVTR-KNAEG------------------------------------------------------------ ------------AMDLLRELKNMP--ITLHLLQSTRVGMSVNALRKQSSDE-ELIALAKSLIKSWKKLL----------- ------------------------------------------DVSDGKSRNQGRGTPLP-----------TSSSKDASRT TDL--------------------------------------------------------------SCKKPDPPRT----- --------PSTP----RITTFPQVPITCDAVRNKCREMLTLALQTDH---DH--VAVGVNCEHLSSQIEEC--------- --IFLDVG----NTDMK----YKNRVRSRISNLKDAKN--------PGLRRNVLCGAITPQQIAVMTSEEMAS------D ELKEIRKAMTKEAIREHQMARTG-GTQTDLFTCNKCRKKNCT-----------YTQVQTRSSDEPMTT--YVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Canis_familiaris_TCEA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------EG------------------------------------------------------------ ------------AMDLLRELKAMP--VTLHLLQSTRVGMSVNALRKQSSDE-EVIALAKSLIKSWKKLL----------- ------------------------------------------DASDAKAREQRRAGPPP-----------TSSSKEAPEA KDP--------------------------------------------------------------SRKRPELPRV----- --------PSAP----RITTFPPVPVTCDAVRNKCREMLTAALQTDH---DH--MAVGADCEGLSAQIEEC--------- --IFRDVG----NTDMK----YKNRVRSRISNLKDAKN--------PDLRRNVLCGVITPQQIAVMTSEEMAS------D ELKEIRKAMTKEAIREHQMARTG-GTQTDLFTCGRCRRKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WK------------------------------------------------------------------------------ ----------- >Monodelphis_domestica_TCEA2 -------------------------------------------------------------------------------- ------------------------------------------GGAGAGTTRPKMQRGGAAEPEARPERAAHGTMMGKEEE IVRIAKRLDKMVTK-KSTDG------------------------------------------------------------ ------------AMDLLKELKSMP--ITLDLLQSTRIGMSVNALRKQSTDD-EVISLAKSLIKSWKKLL----------- ------------------------------------------DASEDKNDEKKRNSSLA-----------TSSSKDASDT KDQS-------------------------------------------------------------SNKKQDPPRT----- --------ISTP----KITTFPPIPITCDAVRNKCREMLTAALQTDN---DH--VAIGADCEHLSAQIE----------- --EYILKEGLPENTDMK----YKNRVRSRISNLKDSKN--------PDLRKNVLCGAITPEQIAVMTSEEMAS------N ELKEIRKAMTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WKVG---------------------------------------------------------------------------- ----------- >Gallus_gallus_TCEA2 -------------------------------------------------------------------------------- --------------------------------------------------------------------------MGGEEE IVRIAKRLDKMVAK-KSADG------------------------------------------------------------ ------------AMDLLKELKSMP--MTLDLLQSTRIGMSVNALRKQSSDE-EVIALAKSLIKSWKKLL----------- ------------------------------------------DASEEKSEEKKKNLSLP-----------TSSSKETGNS RDQS-------------------------------------------------------------SNKRQEPPKT----- --------PTTP----KITTFPPAPVTCDAVRNKCREMLTTALQADD---DY--IAIGADCEHIAAQIE----------- --ECIYQD--IKNTDMK----YKNRVRSRISNLKDSKN--------PELKKNVLCGAITPEQIAVMTSEEMAS------N ELKEIRKAMTKEAIREHQMAKTG-GTQTDLFTCGKCKKKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WKVAHQGYYWH--------------------------------------------------------------------- ----------- >Anolis_carolinensis_TCEA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------AMGGEQE IVRIAKRLDKMVAK-KSAEG------------------------------------------------------------ ------------AMDLLKELKSMP--ITLHLLQSTRIGMSVNALRKQSTDE-DVIALAKSLIKAWKKLL----------- ------------------------------------------DASEDKGNEKKRN-SLP-----------TSSSRESGDS KDQS-------------------------------------------------------------SIKRQDLPKT----- --------PTTP----KITTFPPVPITCDTVRSKCREMLTSALQTDN---DY--VAIGVDCEEMAAQIEAF--------- --ELIYQD--VKNTDLK----YKNRVRSRISNLKDSKN--------PDLRKNVLCGVITPEQIAVMTSEEMAS------N ELKEIRKAMTKEAIREHQMAKTG-GTQTDLFTCGKCRKKNCT-----------YTQVQTRSSDEPMTT--FVVCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Danio_rerio_TCEA2_a -------------------------------------------------------------------------------- --------------------------------------------------------------------------MVKDQE VERIAKKLDKMVHK-KNTDG------------------------------------------------------------ ------------AIDLLQELKNMK--MSLETLQSTRIGMSVNAVRKQSSDE-EVQTLAKSLIKAWKKLLDG--------- -----------------------------------------SEG---KPEEKKGESPLQ-----------SSSSKDCPGS SDT------------------------------------------------------------SNKPETPKTPTT----- --------PVTP----KFTMFPPAPVTTDSVRTKCRELLVAALQTDG---DH--QTIGADCEHMAAQIEDY--------- --IYQEFK----STDMK----YKTRLRSRISNLKDQKN--------PDLRRNVLCGNISPERIASMTAEEMAS------P ELKEIRKALTKESIREHQLSKVG-GTETDMFVCGKCKGKNCT-----------YTQVQTRSADEPMTT--FVLCNECGNR WKFC---------------------------------------------------------------------------- ----------- >Oryzias_latipes_TCEA2_b -------------------------------------------------------------------------------- ------------------------------------------------------------------------TAMAKNQE VERIAKKLDKMVQK-ENTEG------------------------------------------------------------ ------------ALDLLKELQNIK--MSLETLQSTRVGMSVNAVRKQSSDE-EVQTLAKSLIKSWKRLLDG--------- -----------------------------------------SEGKSEKKEKKKEGSPLR-----------SSSTSSDSGS SGKRHCSA-----------------------------------------------------KSGDTPTTPNTPST----- --------PTLPP---LITSFPPAPVTSDSVRNKCRELLVAALQTDD---DY--KTIGVDCDHLAAQIEHH--------- --IFQEFK----STDMK----YKARLRSRISNLKDQKN--------PDLRRNVLCGNISAQRIACMTAEEMAS------A ELKQIREALTKESIREHQLSKVG-GTETDMFICSKCHGKNCT-----------YTQVQTRSADEPMTT--FVLCNGCGNR WKFC---------------------------------------------------------------------------- ----------- >Homo_sapiens_TCEANC -------------------------------------------------------------------------------- --------------------------------------------MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQ IAARASLIEQLMSKRNFEDLG----------------------------------------------------------- --------------NHLTELETIY--VTKEHLQETDVVRAVYRVLKNCPSV-ALKKKAKCLLSKWKAVYK---------- ---------------------------QTHSKARNSPKLFPVRGNKEENSGPSHDPSQNE--------TLGICSSNS-LS SQD-------------------------------------------------------------VAKLSEMIVPENRAIQ LKPKEEHFGDGDPESTGKRSSE-LLDPTTPMRTKCIELLYAALTSSSTD-----QPKADLWQNFAREIEEH--------- --VFTLYS----KNIKK----YKTCIRSKVANLKNPRN--------SHLQQNLLSGTTSPREFAEMTVMEMAN------K ELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMT--YVICNECGEQ WYHSKWVCW----------------------------------------------------------------------- ----------- >Gorilla_gorilla_TCEANC -------------------------------------------------------------------------------- --------------------------------------------MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQ IAARASLIEQLMSKRNFEDLG----------------------------------------------------------- --------------NHLTELETIY--VTKEHLQETDVVRAVYRVLKNCPSV-ALKKKAKCLLSKWKAVYK---------- ---------------------------QTHSKERNSPKLFPVRGNKEENSGPSHDPSQNE--------TLGICSSNS-LS SQD-------------------------------------------------------------VAKLSEMIVPENRAIQ LKPKEEHFGDGDPESTGKRSSE-LLDPTTPMRTKCIELLYAALTSSSTD-----QPKADLWQNFAREIEEH--------- --VFTLYS----KNIKK----YKTCIRSKVANLKNPKN--------CHLQQNLLSGTTSPREFAEMTVMEMAN------K ELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMT--YVICNECGEQ WYHSKWVCL----------------------------------------------------------------------- ----------- >Mus_musculus_TCEANC -------------------------------------------------------------------------------- --------------------------------------------------------------------------MSDKNQ IIARASLIEQLVSKRYFEDIG----------------------------------------------------------- --------------KQLTELEMIY--VSKEHLQETDVVRAVYRVLKNCPSV-TLKKKAKCLLAKWRGFYK---------- ---------------------------STHCKPRQSPKVLHTNANKEESAAVSQDVSQDETSGSSHSEIMGLCSSLSRLL PQD-------------------------------------------------------------AAKPAAAIGSESSTAQ MEINEGYLKGDDSECTRKSSGV-FQGTLVSVRSKCVELLYTALASSCTD-----HTEVHIWQNLAREIEEH--------- --IFTLHS----NNIKK----YKTSIRSKVANLKNPRN--------FHLQQNFLSGTMSAREFAEMSVLDMAS------Q ELKQLRASYTESSIQEHCLPQSVDGTWTNKIKCRRCDKYNCKVTVIARGTLFLPSWVQNSNPDE-QMT--YVICNECGEQ WYHNNWVCL----------------------------------------------------------------------- ----------- >Canis_familiaris_TCEANC -------------------------------------------------------------------------------- -----------------------------------------------------------------------AVKMSDKNQ IAASASLIEQLLSKRNFEDLG----------------------------------------------------------- --------------NHLTDLETLC--VTKEDLQETIVVRAVYRVLKHCPSV-ALKKKAKHLLSEWKALYKK--------- ---------------------------DLHFKPRD--KSFPTGRN-EENSRLSHDPSQDE--------LSGGSSSNS--S SHS-------------------------------------------------------------VAEAFEMIVPENSTSQ TEPKEEHFRSGDPKSTAQRSSE-LLDPMVPVRAKCTELLYEALTSPFTE-----QPKADLWRNFAREIEEH--------- --IFTLHS----KNLKK----YKTCVRSKVANLRNPKN--------SHLQQNLLSGTMSPREFAKMTVMEMAN------K ELKQLRASYTESCIQEHHLPQAIEGTHTRKIKCRRCEKFNCKVTVIARGTLFLPSWVRNSNPDEEMMT--YVICNECGEQ WYHSKWVCL----------------------------------------------------------------------- ----------- >Gallus_gallus_TCEANC -------------------------------------------------------------------------------- --------------------------------------------------------------------------MSDQKN IIYRIHCIEKLLSENNFQDIE----------------------------------------------------------- --------------DHLKELEDVS--MTVEYLQGTEVAKVVYRILKSCPSA-ELKKKAKQLLSRWKALYK---------- -----------------------------NNRLQSVQVKKSVSVCVSEATEHL-EIPGEQ-------LLSEGPCQQEVLD AVPSKILVPPR-----------------------------------------------------TVKKVASNNADGSRDQ LSPFEEGHTDNEGSKPLVNEAGSQQDHMRALRCKCTDLLYKALTGSAKD-----KEETDKWLELSKEIEEH--------- --VFALHC----KNDKK----YKNCIRSKISNLKNPKS--------CNLKHNLFSGTLSPKAFAEMTVMEMAS------D ELKQLRALYTESSIQEHQLPQVINGTQTNKIKCRRCEKSDCTVTMIARGTLFLPGWVRSTNPDEQMLT--FVICNECGEQ WYHSRWICL----------------------------------------------------------------------- ----------- >Anolis_carolinensis_TCEANC -------------------------------------------------------------------------------- --------------------------------------------------------------------------MSNTKV LTSRADCIEKLLSERKYQDIV----------------------------------------------------------- --------------IHLTYLETAD--ITIDDLQETDVAKAVFRVSQNCPSV-VLKKKAKHLLSKWKAIYK---------- -----------------------------KHCSPSVQLHLGLSENANEDSGHIQVVSEDV-------NSIGKLNQQDKLC SAS---------------------------------------------------------------PSLASESPSSNPSS CVQKDNTTQPDLGNGSSISETGQQHGPIMAVRGKCTQLLFEALTDSSTS-----NEEIAKHHQTAEEIEQH--------- --IFALHA----GNDRK----YKNSIRSKVSNLKNPKN--------YHLKHSLHIGVLSPQTFAGMSAVEMAH------D ELKQLRASYTKSAVQEHQLPQRISGTLTNKIKYG-----------------------------EPTVL--FLILDSS--- -------------------------------------------------------------------------------- ----------- >Xenopus_tropicalis_TCEANC -------------------------------------------------------------------------------- -----------------------------------------------------------------------MLHKDINKE LVSRALEVENLLAERKYEDLA----------------------------------------------------------- --------------FHLTYFEKAE--VTSGILQGTDIVRVVYRVLKTCPRG-ALKLKAKVLLSKWKKLYRK--------- ---------------------------CCHETSCICEHCSKICENKEGPEKLAVDIQDQV-----------HNSEQKILI NKS---------------------------------------------------------------TSSPSSYKFNLNKS DSSAQDCYGNHEESVTDHEVPKKVNAEDLALRTKCTELLYQALREDSEC-----QEKL---QNLAKAIEEN--------- --IYKIHA----GNTKK----YRNCIRSKISNLKNPKN--------SHLKMQILSRALSPKVFAEMGVMEMAC------D ELRNLRANYTETCVQEHQLPQGVDGVHTNKIRCRRCDKFNCTVTMISRGTLFLPGWVRTGNPDEEMMT--FVICNECGEQ WYHNRWVCL----------------------------------------------------------------------- ----------- >Tetraodon_nigroviridis_TCEANC_a -------------------------------------------------------------------------------- ----------------------------------------------------------------------------AAMD VVHSVLEIERASRERNYRNIL----------------------------------------------------------- --------------ALLGDLDKAA--ITAEQLEMTDVVKVLYRLLKTCPEV-GVRRAAKALLSRWKKEHS---------- -----------------------------------------QDGDKQENNPELPCRSADVG------------------- --------------------------------------------------------------------AEKVHEDASTS- ------------GDKCGLRAASGASGGFSSVRSKCVQLLLSSLRPEPPE-----QAQA---AELAAAIERH--------- --IHERHR----SNPLK----YKACVRSKVANLRNPQN--------QHLREGLLSASLSPLTFAGMSAEEMAG------A ALRRLREEYSSRGLSERQLPQAAEGTPTRKIRCKRCGGRECRVSQVARGALFLPAWVRRGIPGEDAMT--FVTCSGCGEQ WYHS---------------------------------------------------------------------------- ----------- >Hydra_magnipapillata_TCEANC -------------------------------------------------------------------------------- ------------------------------------------------MMITSIKWIFFLYTLIILIGPCDSKKKSVSVA LRRNARNVKGGNQNTENLKGRPGQGYYIALEIG----------------------------------------------- --------TPPQRINVLVDTGSSN--FAVAATPHPYLPVYFHPDRSSTFTDLNRAVAVPYTQGNWEGKLGSDLIRFIDAP NATVRVN----------------IAAIHSSENFFINGSNWEGILGLGYARLSKPDSSVTPLFDQFVISDVVEDTFSMQLC STS------------------------------------------------------------ELDPSSEPTVAGTMVFG EMDDDLYKGDMLYTPIVKKWYYEVVITDMSVNGISLGVHCKKYNYDKTIVDSGTTNLRVPEEIFNLILTQLKKYDKLGVP DEFWIGRQMMCWNYDKTPWEEFPHMSISLLSSLSSSKEFVLKIPPQLYLRETIERGPLPGQHCYKFAITKAEKGTVIGAV VMEGFYVVFDRENIRVG-FAATTCGAEGRLNPRSEVSGPFIRADP------TDCEYIESELADTALLTVAYVMAGVCGLC LLPVFVLLGQASCKKSVEKAGVPRDY------------------------------------------------------ -----------