>Homo_sapiens_SNTA1 -------------------------------------------------------------------------------- ---------------MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVS--PADGDPGPEPG--------A PREQEPAQLN----------------------------------------------------GAAEPGAGP-PQLPEALL LQRRRVTVRKADAGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGK EVVLEVKY----------------------------------------------------MKDVSPYFKN-----STGGT SVGWDSPPASPLQRQP-------SSPGPTPR-------------NFSEAKHMSLKMAYVSKRCT---PNDPEPRYLEICS ADG-QDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDE-LQALLAATS-TAGSQDIKQIGWLTEQ-------------- -----------------------LPSGG---TAPTLA---LLTEKELLLYLSLPETREALSRPARTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAA WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCSLSVHIDKGFTL----WAAEP---------------GAARA VLLRQPFEKLQMSSDDGASLLFLDFGG------AEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pan_troglodytes_SNTA1 -------------------------------------------------------------------------------- ---------------MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVS--PADGDPGPEPG--------A PREQEPAQLN----------------------------------------------------GAAEPGAGP-PQLPEALL LQRRRVTVRKADAGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGK EVVLEVKY----------------------------------------------------MKDVSPYFKN-----STGGT SVGWDSPPASPLQRQP-------SSPGPTPR-------------NLSEAKHVSLKMAYVSKRCT---PNDPEPRYLEICS ADG-QDTLFLRAKDEASARSWATAIQAQVNALTPRVKDE-LQALLAATS-TAGSQDIKQIGWLTEQ-------------- -----------------------LPSGG---TAPTLA---LLTEKELLLYLSLPETREALSRPARTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAA WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCSLSVHIDKGFTL----WAAEP---------------GAARA VLLRQPFEKLQMSSDDGASLLFLDFGG------AEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pongo_abelii_SNTA1 -------------------------------------------------------------------------------- ---------------MASSRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVS--PADGDPGPEPG--------A PREPEPAQLN----------------------------------------------------GAAEPGAGP-PQLPEALL LQRRRVTVRKADAGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQALKKTGK EVVLEVKY----------------------------------------------------MKDVSPYFKN-----SAGGT SVGWDSPPASPLQRQP-------SSPGPTPR-------------NLSEAKHVSLKMAYVSKRCT---PTDPEPRYLEICS ADG-QDTLFVRAKDEASARSWATAIQAQVNALMPRVKDE-VQALLAATS-TAGSQDIKQIGWLTEQ-------------- -----------------------LPSGG---TAPTLA---LLTEKELLLYSSLPETREALSRPARTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVETHLFSVESPQELAA WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCSLSVHIDKGFTL----WAAEP---------------GAARA VLLRQPFEKLQMSSDDGASLLFLDFGG------AEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Mus_musculus_SNTA1 -------------------------------------------------------------------------------- ---------------MASGRRAPRTGLLELRCGAGSGAGGERWQRVLLSLAEDALTVS--PADGEPGPEP---------- ----EPAQLN----------------------------------------------------GAAEPGAAP-PQLPEALL LQRRRVTVRKADAGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQALKKTGK EVVLEVKY----------------------------------------------------MKEVSPYFKN-----SAGGT SVGWDSPPASPLQRQP-------SSPGPQPR-------------NLSEAKHVSLKMAYVSRRCT---PTDPEPRYLEICA ADG-QDAVFLRAKDEASARSWAGAIQAQIGTFIPWVKDE-LQALLTATG-TAGSQDIKQIGWLTEQ-------------- -----------------------LPSGG---TAPTLA---LLTEKELLFYCSLPQSREALSRPTRTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAA WTRQLVDGCHRAAEGIQEVSTACT---------WNGRPCSLSVHIDKGFTL----WAAEP---------------GAARA MLLRQPFEKLQMSSDDGTSLLFLDFGG------AEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Rattus_norvegicus_SNTA1 -------------------------------------------------------------------------------- ---------------MASGRRAPRTGLLELRSGAGSGAGGERWQRVLLTLAEDALTVS--PADGEPGPEP---------- ----EPAQLN----------------------------------------------------GAAEPGAAS-PQLPEALL LQRRRVTVRKADAGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQALKKTGK EVVLEVKY----------------------------------------------------MKEVSPYFKN-----SAGGT SVGWDSPPASPLQRQP-------SSPGPQPR-------------NLNEAKHVSLKMAYVSRRCT---PTDPEPRYLEICA ADG-QDTLFLRAKDEASARSWAGAIQAQISTFIPWVKDE-LQALLTATG-TAGSQDIKQIGWLTEQ-------------- -----------------------LPSGG---TAPTLA---LLTEKELLLYCSLPQTREALSRPARTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAA WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCNLSVHIDKGFTL----WAAEP---------------GATRA VLLRQPFEKLQMSSDDGMSLLFLDFGG------AEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Canis_familiaris_SNTA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------MPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGK EVVLEVKY----------------------------------------------------MKEVSPYFKN-----SAGGT SVGWDSPPASPLPRQP-------SSPGPSPR-------------DLSDAKHMSLKMAYVSRRCT---STDPEHRYLEICS ADG-QDTLFLRAKDEASAKSWAAAIQAQVNALMPWVKDE-LQALLAATS-TTGSQDIKQIGWLTEQ-------------- -----------------------LPNGG---TAPTLA---LLTEKELLLYCHLPQTREALSQPSRTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAT WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCSLSVHIDKGFTL----WAAEP---------------GAARA VLLRQPFEKLQMSSDDGASLLFLDFGG------AEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Felis_catus_SNTA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------GGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGK EVVLEVKY----------------------------------------------------MKEVSPYFKN-----SAGGT SVGWDSPPASPLQRQL-------SSPGPPPR-------------DISDAKHISLKMAYVSRRCT---PTDPEPRYLEICS ADG-QDTLFLRAKDEASAKSWAAAIQAQVNALMPWVKDE-LQALLAATS-TAGSQDIKQIGWLTEQ-------------- -----------------------LPGGG---TAPTLA---LLTEKELLLYCHLPQTREALSQPARTAPLIAT-------- -----------------RLVHS--------------GPS----KGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAA WTRQLVDGCHRAAEGVQEVSTACT---------WNGRPCTLSVHIDKGFTL----WAAEP---------------GAARA VLLRQPFEKLQMSSDDGASLLFLDFGG------AEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Monodelphis_domestica_SNTA1 -------------------------------------------------------------------------------- ---------------MAAGRRSPKSGLLELRAPG--SAGPGPWLRVLVSLAADVVTVSAAPASGEPEPGPG--------P VSELVSASLPQLNGADPG--------------------------------------------APAAPGAPPTPPLPHALL NQKRTVRVVKQEAGGLGISIKGGQEN--KMPILISKIFKGLAADQTEALFVGDAILSVNGGDLSTATHDEAVQVLKKTGK EVVLEVKY----------------------------------------------------MKEISPYFKN-----SSSGA TVGWESPTAS--------------SPTLCPR-------------DLKEGKNVSLKMAYVSRRCI---PADAERRYLELRS ADG-RDILFLRAKDEASAQAWLAALQANIGVLVPWVTDE-LRALLAAAGGVSGSTEIKRIGWLTEQ-------------- -----------------------LSGGG---TEPVLA---VLTEKDLLFYSSLPQNRDALSAPARSSPLIAT-------- -----------------RLVHS--------------GPS----KGSVLYDSELSFALRSGTHQGVETHLFSVESPRDLSS WTRLLVDGCHNAAETVQEVSTACT---------WNGRSCSLSVHIDKGFTL----WAVEP---------------GLAKT LLLQEPFEKLQMSSDDGSSLLFLDFGG------TEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLA------------- -------------------------------------------------------------------------------- ----------------------------------------------- >Anolis_carolinensis_SNTA1 MLWNQGSCGMVKVREIKVRESTARSLSRSKRCQPALVPPCGGAGREAPGALLGGRRGGGGGGAGAWVRPPKAAESERARK GRAKEGRQEGRNALKMAAGRRAPKSGLLELR------APGEQWLRVLLALSEDFLSVS--PGGGGGGGGGK--------G PEETPPSSPG-----------------------------------------------------QLNGGDPPPALVPDALT NIKRTVRIVKQDVGGLGISIKGGREN--KMPILISKIFKGLAADQTEALFVGDAILSVNGADLSDATHDEAVQALKKTGK EVVLEVKY----------------------------------------------------MKEISPYFKN-----SSTGA TVSWDSSPAAFQKQ---------ASPSLSLR-------------DLNEGKNIPLRMCYISRKCL---PSDPENRYLEVCS ADG-RIPLFLRAKDEASAQAWFNAIHSNISALLPRVREE-LRALQSGAG-IAGSRDIKHVGWLTEQ-------------- -----------------------LPGDG---TKNILA---ILTEKELLFYSCLPQSRDALGKPTHSFPLIAT-------- -----------------RLVHS--------------GPS----KGSLLYDSELSFALRTGTKKGVETHLFSVETHRDLAM WTRMLVDGCHNAAECVQEVSTACT---------WNGRDCTLSIHIDKGFTI----SALEP---------------GLAKV ILLQQPFERLQMSSDDGAKMLYLDFGS------SEGEIQLDLHSCPKTIVFIIHSFLSAKVTRMGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Xenopus_tropicalis_SNTA1 -------------------------------------------------------------------------------- ---------------MASPGTAHRSGLLELR------CPGERWVRVLLLLGEETVTFT-------PEPEPG--------- --AAEEKALN---------------------------------------------------------GAEPAGGVPESLI NLRRTVRVLKQDAGGLGVSIKGGREN--KMPILISKIFKGLAADLTGSLYVGDAILSVNGVDLSEATHDDAVQALKKTGK EVVLEVKY----------------------------------------------------MKEISPYFKG-----SPP-- ----SGSPAAPLQKR--------GSPALPPK-------------EYKDGKSIPLKMCYVSRRFL---PTDTEPRYLEICS ADG-RDVLFFRAKDEGTAQSWFNAIHTNASALAPRVRED-VKQLL--------GKDIKQMGWLTEQ-------------- -----------------------LPQDG---KRNLLA---LLTEKDLLLYNSLPHSREGFSKP-YCHPLIAT-------- -----------------RLVHS--------------GPS----KSSPLYDTELAFALRSGTQKGVETHLFSVETQRELAT WTRVLVDGCHSAAELIKEVTTACT---------WGGNECALSIHIDQGFTL----FTEEP---------------GLNKV IHFHQPFEKLRMSSDDGVRILYLEFGN------PEAELQLDLHSCPKTIVFIIHSFLSAKVSRLGLFT------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Takifugu_rubripes_SNTA1_a -------------------------------------------------------------------------------- ---------------MAAAMKAQKTGLLELR------VTVDRWRRVLATLTEDTLTVN----PSEASEEPA--------K -AAPTPVGALN-----------------------------------------------------GDPPNLSSSPVPETIT NVKRTVRVTKQDVGGLGISIKGGKEN--KMPILISKIFKGLAADQTEALYVGDAILSVNSYDLREATHDEAVQALKKTGK EVVLEVKY----------------------------------------------------IKEMSAFFKSS----GSPGG ALPWDSPPSTPQR-----------TSEPLPA-------------EVKEPRSIPLKMCQVSRKQC---PPDTENRYFEVIS ATR-KNSVFLRAKDPAMAQSWYNAIQNSIANLLPRMKDE-MKVMQPG-------MEVKHVGWITEQ-------------- -----------------------VIQGP---EKPVLA---VLTDRDLLLYPSLPESKEGLKSPTKSHPLITT-------- -----------------RLVHS--------------GPG----KSSPLLDSDLSFGLRTGTKQGVETHVFRVDSAKDLST WTHLLVEGCHNAAELIKEVTTACS---------WNGKECTLGVHIDEGFTL----FTEEM---------------GVRKR ILLQHPFEHLKMSSDDGVRMMFLDFGG------PEAEIQLDLHCCPKTLVFIIHSFLSAKVKRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Tetraodon_nigroviridis_SNTA1_a -------------------------------------------------------------------------------- ---------------MAAAMKAQKTGLLELR------VTVDRWMRVLATLTEDTLTVN----PGEATEEPA--------K -AAPTPAGAIN-----------------------------------------------------GDPPNLSSSPVPETIT NVKRTVRVTKQDVGGLGISIKGGKEN--KMPILISKIFKGLAADQTEALYVGDAILSVNSYDLREATHDEAVQALKKTGK EVILEVKY----------------------------------------------------IKEMSAFFKSS----GSPGG ALPWDSPPSSPQR-----------TSEPLPA-------------EVKEPRSIPLKMCQVSRKQC---PPDTENRYFEVVS STR-KNSMFLRAKDPAMAQSWYNAIQAGIANLLPKVKDE-MKVMQPG-------MEVKHLGWITEQ-------------- -----------------------VTQGP---ERPVLA---VLTDRDLLLYPSLPDSKESLNSPTRSHPLITT-------- -----------------QLVHS--------------GPG----KSSPLLDSDLSFGLRSGTKQGVETHVFRVDSAKDLSA WTHLLVEGCHNAAELIKEVTTACS---------WNGKECTLGVHIDEGFTL----FTEEM---------------GVRKR VLLQHPFERLKMSSDDGVRMMFLDFGG------PEAEIQLDLHCCPKTLVFIIHSFLSAKVKRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Gasterosteus_aculeatus_SNTA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------GGKEN--KMPILISKIFKGLAADQTEALYVGDAILSVNGYDLREATHDEAVQALKKTGK EVILEVKY----------------------------------------------------IKEMSAFFKNS----GSPGA TLPWDSPPSTPHT-----------GTELSPA-------------EVKEPRSIPLKMCQVSRKQC---PPDTENRYFEVIS SSR-RNSVFLRAKDPAVAQSWYNAVQAGAASLLPRVKEE-MRSMQQG-------VEVKHLGWITEQ-------------- -----------------------VCKNADVHEKPVLA---MLTDRDLLLYPSLPESKESLGNPAKSHPLIAT-------- -----------------RLVHS--------------GPG----KSSPLLDSDLSFGLRSGTKQGVETHVFRVDSAKELST WTHLVVEGCHNAAELVKEVTAACS---------WNGKECTLGVHIDEGFTL----FTQEM---------------GVRKS ILLQQPFERLRMSSDDGVRMMFLDFGG------QEAEIQLDLHSCPKTIVFIIHSFLSAKVKRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Oryzias_latipes_SNTA1_a -------------------------------------------------------------------------------- ---------------MAAAMKTQKTGLLELR------VTVDRWVRVLATLTEDALTLN----PGDSADEPA--------K PGHQSPAGAVN-----------------------------------------------------GDPPNLSSSPVPETIT NVKRTVRVTKQDVGGLGISIKGGKEN--KMPILISKIFKGLAADQTEALYVGDAILSVNGYDLREATHDEAVQALKKTGK EVILEVKY----------------------------------------------------IKEMSAFFKSS----GSPGA SLPWDSPPSTPQR-----------DPELSPA-------------EGKEPRSVPLKMCQVSRKQC---PPDTEDRYFEVTS FNR-KNSVFLRAKDPAMAQSWYNAIQAAAGSLLPQVKEE-LKIMQPG-------VQIKHVGWMTEQKKYLK--------- ---------------------IDMRQGP---EKAVLA---VLTEKDLLLFPSLPENKQSLSSPTKSHPLITT-------- -----------------RLVHS--------------GPG----KSCLHADSELSFGLRSGTRQGVETHVFRVDSAKELSA WTHLLVEGCHNAAELIKEVTTGTE---------PSRK-RAVQFLRDSTPEV----FSADP---------------IGLLF FLYKDFYSILAFETLDFFLCIYPNQG-------FSSPQQLDLHCCPKTLVFIIHSFLSAKVRRLGLLA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Drosophila_melanogaster_SNTA1 -------------------------------------------------------------------------------- -MVESSSLGRTPPAAQQPIPQQHSPSPSGLRCGNMETRVRGAWYRVLVTLETDFLAVSLDESCEAAQPSNDGQSTTLNGT LGSNHSGGGGGGAGGGGTGGGGQNGTLPNSASLQGMNIQDTELDGSASNDNGDRDPCLNNNNNAGDGGGMDMCDVPDHVA NQKRHVRIIKSDNNGLGISIKGGREN--RMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGR VVDLEVKF----------------------------------------------------LREVTPYFRK-----ASIIS EVGWELQRAFLCPLGPGV----PTSP-PAPKTT-----------PRADTRYIPLQLTHLARNLK---YIDPENRCFELHS PDG-VHSCILRAADSAEALVWFNALHSAMGTSTQRALAEANRALTNLIG------ELKHIGWLSKRMSGGGSSGSAGGGA ASGGSGTSNSVVAGELPSGRSSSESSDESDKWLPIFVA---VTEREFRIYESAPWSVEAWSRPLEIYALATT-------- -----------------RLAG--------------AGNNS--SLNGQ---QTTVFCVRCGTARGVLVYWLRSETHRDMAA WARSLVQGSHQAVNYQREFSFRCL---------FQGRQCQLVVHINRGFFLYDCGGFAPTT-----------PTVATAKT QLWQFAFDKLKGSADDGARMLYLDFG------EDG-EIELDMECCPKPVVFVVHNCLSAKVHNIA--------------- -------------------------------------------------------------------------------- ----------------------------------------------- >Homo_sapiens_SNTB1 -------------------------------------------------------------------------------- ---------MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIG---------- -TATNGSFCRGAGAGHPGAG------------GAQPPDSPA---------------------GVRTAFTDLPEQVPESIS NQKRGVKVLKQELGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGG-------STSDPPSS---------QSFSFHRDRKSIPLKMCYVTRSMA---LADPENRQLEIHS PDA-KHTVILRSKDSATAQAWFSAIHSNVNDLLTRVIAE-VREQLGKTG-IAGSREIRHLGWLAEKVP------------ ------------------------GES-KKQWKPALVV---LTEKDLLIYDSMPRRKEAWFSPVHTYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSH WTRSIVQGCHNSAELIAEISTACT---------YKNQECRLTIHYENGFSI----TTEPQ--------------EGAFPK TIIQSPYEKLKMSSDDGIRMLYLDFGG------KDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pan_troglodytes_SNTB1 -------------------------------------------------------------------------------- ---------MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIG---------- -TATNGSFCRGAGAGHPGAG------------GAQPPDSPA---------------------GVRTAFTDLPEQVPESIS NQKRGVKVLKQELGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGG-------STSDPPSS---------QSFSFHRDRKSIPLKMCYVTRSMA---LADPENRQLEIHS PDA-KHTVILRSKDSATAQAWFSAIHSNVNDLLTRVIAE-VREQLGKTG-IAGSREIRHLGWLAEKVP------------ ------------------------GES-EKQWKPALVV---LTEKDLLIYDSMPRRKEAWFSPVHTYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSH WTRSIVQGCHNSAELIAEISTACT---------YKNQECRLTIHYENGFSI----TTEPQ--------------EGAFPK TIIQSPYEKLKMSSDDGIRMLYLDFGG------KDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Mus_musculus_SNTB1 -------------------------------------------------------------------------------- ---------MAVAAAAVAA-PAGGGGARAQRSGLLEVLVRDRWHKVLVNLSEDALVLSCEEGAAAYNGIG---------- -AATNGSFCRGSGTGHPVPG------------VAQAPDSPA---------------------GVRTAFTDLPEQVPESIS NQKRGVKVLKQELGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGG-------GSAEPLSS---------QSFSFHRDRKSIPLKMCYVTRNMT---LADPENRQLEIHS PDA-KHTVILRSKDSATAQAWFSAIHSNAGDLLTRVVAD-IREQLGKTG-IAGSREIRHLGWLAEKVP------------ ------------------------GES-EKQWKPALVV---LTEKDLLIYDSMPRRKEAWFSPVHSYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQAGMDLSFATRTGTKQGIETHLFRAEISRDLSH WTRSIVQGCHNSAELTAEITTACT---------YRNQECRLTIHYDNGFSI----STEPQ--------------DGAFPK TIIQSPYEKLKMSSDDGIRMLYLDFGG------KEGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Felis_catus_SNTB1 -------------------------------------------------------------------------------- -----------------------------------------------VNLSEDALVLSCEEGAAAYNGIG---------- -TATNGSFCRGAGG-------------------AQPPDSPA---------------------GVRTAFTDLPEQVPESIS NQKRGVKVLKQELGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGG-------GSSDPLSS---------QPFSFHRDRKSIPLKMCYVTRSMA---SADPENRQLEIHS PDA-KHTVILRSKDSATAQAWFSAIHSNVSDLLTQVIAE-VREQLGKTG-IAGSREIRHLGWLADKVP------------ ------------------------GES-EKQWKPALVV---LTEKDLLIYDSMPRRKEAWFSPVHTYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQAGVDLSFATRTGTRQGIETHVFRAETGRDLSH WTRSIVQGCHNSAELVTEVTTACT---------YKNQACCLTIHYENGFSI----TTEPQ--------------EGAFPK TILQSPYEKLKMSSDDGIRMLYLDFGG------KDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Erinaceus_europaeus_SNTB1 -------------------------------------------------------------------------------- --------MAVAAAAAVAAAPAGGGGGRAQRSGLLEVLVRDRWHKVLVNLGEDALVLSCEEGAAAYNGFG---------- -AATNGSFCR---AGASGPS------------GTQSPDSPA---------------------GVRTAFTDLPEQVPEAIS NQKRGVKVLKQEMGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPKLGG-------SSSDPLSS---------QSFSFHRDRKNIPLKMCYVTRSMA---LADPENRQLEIHS PDA-KHTVILRSKDSATAQAWFSAIHSNVSDLLTRVITN-VRDQLGKTG-IAGSREIRHLGWLAEKVP------------ ------------------------GES-EKQWKPALVV---LTEKDLLIYDSMPRRKEAWFSPVHTYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQTGVDLSFATRTGTRQGIETHLFRAEISRDLSH WTRSIVQGCHNSAELITEITTACT---------YKNQECRLTIHYENGFSI----TTEPQ--------------EGAFSK TIIQSPYEKLKMSSDDGIRMLYLDFGG------KDGEIQLDLHTCPKPIVFTIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Gallus_gallus_SNTB1 -------------------------------------------------------------------------------- --------------MAVAAAGGGGGGGRAQRSGWLEVLVRERWHKVLANLGGEALVLSGEERPDGAAHNG---------- -LGGDGAACRGAEGGGGGSA-------------------------------------------VRTAFTDPPEQVPEAVS NKKRCVKVLKQELGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILAVNGTDLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGC-------VSADPLSQ---------LSLSIHRDKKTIPLKMCYVTRNMT---VSDPENRLIEVHS PDA-KHTVVLRSKDSATAQAWFNAIHSSVNDLIPRVIAE-VRDQLGKAG-IAGSREIRHLGWLAEKVP------------ ------------------------GDN-EKHWKPVLVV---LTEKDLLIYESMPRMKEAWFSPLHTYPLLAT-------- -----------------RLVHS--------------GPG----KGSPQSGVDLSFATRTGTRQGIETHLFRTETSRDLSL WTRSIVQGCHNSAELITEITTSCT---------YKSQECRLTIHYEHGFSL----TTEPQ--------------DGAFSK TIAQYPYEKLKMSSDDGIRMLYLDFGG------KDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pelodiscus_sinensis_SNTB1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------MPILISKIFKGLAADQTQALYVGDAILAVNGTDLRDATHDEAVQALKRAGK EVLLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGG-------VSSDPLSQ---------LSLSIHRDRKTIPLKMCYVTRNMA---VSDPENRLLEVHS PDA-KHTVVLRSKDSATAQAWFNAIHSSVSDLIPRVIAE-VKDQLGKTG-IAGSREIRHLGWLAEKVP------------ ------------------------GEN-EKHWKPALVV---LTEKDLLMYDSMPRMKEAWFSPLHTYPLLAT-------- -----------------RLVHS--------------GPT----KGSPQSGVDLSFATRTGTRQGIETHLFRTETSRDLSL WTRNIVQGCHNSAELITEIKTSCT---------YKNQECRLTIHYEHGFSL----TVEPR--------------DGALSK TIVQCPYEKLKMSSDDGIRMLYLDFGG------KDGEFQLDLHSCPKPIVFIIHSFLSAKITRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Takifugu_rubripes_SNTB1_a -------------------------------------------------------------------------------- -----------APKMAVVIAKGVSGACGVRKSGVLEVLVRERWHKVSVNLNEEALTLSCEEDSGNDADDS---------- -VNFN---CNGSYLDNNNAN----------------SNNGH--------------------QHVRPACT---ERVPEAIA NRKRCVKVAKQEIGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNEMNLRDATHDEAVQALKRAGR EVTLEVKY----------------------------------------------------MREATPYVKR-----GSPVS EIGWETLPPESPRLGTPPITS-SPISNPPSP------PTQPFLSPQGDRRCIPLKMCYVTRAMT---TADPENRQLELHS PDT-RHTVVLRCPDQPSALSWFAAMHSVTSSLAQWALAE-VVQNTARMG-IAGSKEIRHLGWLAGKVPQ----------- ------------------------TESEKQSWKPVLVV---VTEKDLLLYDSLPRSKEAWHCPAHIYPLLAT-------- -----------------RLVHS--------------GPD----RGSPHSGTELFFATRTGTRLGIEAHLFRVETTKDLSL WTRHIVNGCHASAEMIKEVTTSCL---------YRGQECRLVIHYEQGFSV----LADPTPLGDRENGEGRKAAAAAPPQ VLLSYPYEKLKMSSDDGIRMLLLDFGG------KEGEIQLDLHSCPKPIVFILHSFLSAKISRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Tetraodon_nigroviridis_SNTB1_a -------------------------------------------------------------------------------- --------------MAVVIAKGVSGACGVRKSGVVEVLVRGRWHKVSVHLNEEALTLSCEGERVGNADDG---------- -VSLS---CNGSYLDNNNAN----------------SNNGQ--------------------QHVRPACT---ERVPEAIA NRKRCVKVAKQEIGGLGISIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGMNLRDATHDEAVQTLKRAGK EVTLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETLPPESPRLGTPPISSPTHLSTPPSP------SAQPFLSPQGDRRCIPLKMCYVTRAMT---TADPENRQLELHS PDT-RHTVVLRCPDQPSALSWFAALHSVTSSLAQRALAE-VVQNTARMG-IAGSKEIRHLGWLAGKT------------- -------------------------ESEKQSWKPVLVV---VTEKDLLLYDSLPRSKEAWHSPAHIYPLLAT-------- -----------------RLVHS--------------GPD----RGSPHSGTELFFATRTGTRLGIEAHLFRVETTKDLSS WTRHIVNGCHASAEMIKEVTTSCL---------YRGQECRLVIHYEQGFSV----LADPTPLGGRENGEEREAANAAKPQ VLLSYPYEKLKMSSDDGIRMLFLDFGG------REGEIQLDLHSCPKPIVFILHSFLSAKISRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Gasterosteus_aculeatus_SNTB1_a -------------------------------------------------------------------------------- -----------APKMAVVITTGVPGVSGVQKSGFLDVLVRERWHKVLVNLNEEALTLSCEEEDCGPDRDS---------- -VTPNGV-TNGSYLDNNNAN----------------SNNGP--------------------HAARTAFTDLPERVPEAIA NRKRCVKVTKQEIGGLGVSIKGGKEN--KMPILISKIFKGLAADQTQALYVGDAILSVNGVNLRDATHDEAVQALKRAGK EVTLEVKY----------------------------------------------------MREATPYVKK-----GSPVS EIGWETPPPESPRLGSPTVLS-SPTSFSFS----------------GDRRCIPLKMCCVTRALT---TPDPENRQLELHS PDA-RHTVVLRCPDQPSALSWFSAMHSVTSKLAKRALSE-VIHSTARTD-VAGSREIRHLGWLAGKVG------------ ------------------------TESEKQCWKPVLVV---VTEKDLLLYESLPRGKEAWQSPAHQYPLLAT-------- -----------------RLVHS--------------GSE----RGSPHSGTELLFATRTGTRLGIETHLFRAETAKDLSL WTRQLVNGCHASAEMIKEVTTSCL---------YQSQECRLVIHYEQGFSV----LADPK-LGDG-------------PQ VLLSYPYEKLKMSSDDGVRMLFLDFGG------EEGEIQLDLHSCPKPIVFILHSFLSAKIYRLGLVA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Branchiostoma_floridae_SNTB1 ------------------------------------------------------------MNEKSLVRPGSAPPPSGMAT WSRDARVPAHGTPVGANMALTAAASAMTRSGLLEVYVRD--RWCRVLVSLEEETLTISLED------------------- -SSVGGG------DQNGD-------------------------------------AIRNSE---FDH-----DQLPESIA NHKRVVKVIKQDVGGLGISIKGGKEN--KMPILISKIFKGLAADQTESLYVGDAILSVNGEDLRDATHDEAVRALKRAGK EVVLEVKY----------------------------------------------------LREVTPYFRR-----STVIG EVGWENASPYVIKEPGA------DNKASTNNF--------------TEMKTIPLKMCYVTRNLT---MPDPEQRTFELHS PDG-RSSCILRCQDASSASQWFAAIHANTSMLTASAMAE-ANSKLVSGRGSAGDREIKHMGWLCEQAHGEG--------- ----------------------GSSS-----WKPVFAA---LTPTDLLLYDTVPWSREEWAVPVQSHPLLATRCSAYFDS -----------------RVGHT--------------GTTPSRSPSGGASGRDLAFGTRTGSR---------VETQRDLAA WTRLIVQLCHQAAEDMKEVIQACF---------WQGRECKLMVHYESGFTL----MDNSNPNE-------------SQSD VLWNFPFERMRMSADDGVGRLWLDFGG------AEGEQQLDMCTGPKPIVFIIHNFLSAKVTRMGLFA------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Anopheles_gambiae_SNTB1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------GIAEICDVPDSVA NQKRHVRVIKSDNNGLGISIKGGREN--RMPILISKIFRGMAADNAKGLYVGDAILSVNGEDLRDATHEEAVRALKRAGR VVDLEVKF----------------------------------------------------LREVTPYFRK-----ASIIS EVGWELQRAFLCPLGPNA----SSPPGVAPRSP-----------PRADTRYIPLQLTHLARNLK---YHDPENRCIELHS PDG-IHSCILRAMDPQEATTWFNALHSAIGKSTQKALLDANRALVSIIG------ELKHIGWLSRRSGGGEYTHTHTHRS TAETGPNSQALAALVRLNGRSSSESSDELDKWQSIFVA---VTDRELRLYESAPWSVEAWSRPFESCPLVAT-------- -----------------RLAG--------------AGNTS--TVGSNSSTHSSVFCIRCGTTRGVVSHWLRSETNRDMAA WARVLVQGCHNAIICQREFSFRCL---------FQGRPCQLIVHLDRGFTLLDSG-------------------LGPASK ALWTFPFDKLKGSADDGNKLLYLDFSGT----EDGAELELDMECCPKPVVFVLHNCLSAKVHSLA--------------- -------------------------------------------------------------------------------- ----------------------------------------------- >Homo_sapiens_SNTB2 -------------------------------------------------------------------------------- -------MRVAAATAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAELEPALG--------P AAAAFNGLPNGGG--AGDSLPGSPSRGLGPPSP---------------------------------PAPPRGPAGEAGAS PPVRRVRVVKQEAGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGAAPQSPSFSG-------SEDSGSPK----------HQNSTKDRKIIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSS WTRILVQGCHAAAELIKEVSLGCM---------LNGQEVRLTIHYENGFTI----SRE----------------NGGSSS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pan_troglodytes_SNTB2 -------------------------------------------------------------------------------- -------MRVAAATAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDASAAELEPALG--------P AAAAFNGLPNGGG--AGDSLPGSPSRGLGPPSP---------------------------------PAPPRGPAGEAGAS PPVRRVRVVKQEAGGLGISIKGGREN--PMPILISKIFRGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGAAPQSPSFSG-------SEDSGSPK----------HQNSTKDRKIIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSS WTRILVQGCHAAAELIKEVSLGCM---------LNGQEVRLTIHYENGFTI----SRE----------------NGGSSS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Pongo_abelii_SNTB2 -------------------------------------------------------------------------------- -------MRVAAA---AGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAELEPALG--------P AAASFNGLPNGGG--AGDSLPGSPSRGLGPPSP---------------------------------PAPPRGPAGEAGAS PPVRRVRVVKQEAGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGAAPQSPSFSG-------SEDSGSPK----------HQNSTKDRKIIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSS WTRILVQGCHAAAELIKEVSLGCM---------LNGQEVRLTIHYENGFTI----SRE----------------NGGSSS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Mus_musculus_SNTB2 -------------------------------------------------------------------------------- ----------------------MAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAVEPE------------P PAAAFNGLPNGGGG---ESLPGSPNRGLGPPSP---------------------------------PAPPRGPAGEASAS PPVRRVRVVKQEAGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGASPQSPSFSG-------SEDSGSPK----------HQNTTKDRKVIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLST WTRILVQGCHAAAELIKEVSLGCT---------LSGQEVRFTVHYEHGFTI----TRD----------------NGGASS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Rattus_norvegicus_SNTB2 -------------------------------------------------------------------------------- ----------------------MAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAVEPE------------P PAVAFNGLPNGGGGGG-DSLPGSPNRGLGPPSP---------------------------------PAPPRGPAGEASAS PPVRRVRVVKQEAGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGASPQSPSFSG-------SEDSGSPK----------HQNTTKDRKVIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLST WTRILVQGCHAAAELIKEVSLGCT---------LSGQDVRFTVHYEHGFTI----TRD----------------NGGTSS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Canis_familiaris_SNTB2 -----------------------------------------------------------MNNETPRGERPAPPPRAGRGK RRGCPTGMRVSAAAAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAEPEAALG--------P AAAAFNGLPNGGG--AGDSLPGSPSRGLGPPSP---------------------------------PAPPRGPAGEAGAS PPVRRVRVVKQEAGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGK EVLLEVKF----------------------------------------------------IREVTPYIKK-----PSLVS DLPWEGASPQSPSFSG-------SEDSGSPK----------HQNSTKDRKVIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFVAIYTNIMALLPQVLAE-LNAMLGATSTAGGSKEVKHIAWLAEQAK------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDCMPWTRDAWASPCHSYPLVAT-------- -----------------RLVHS--------------GSG----CRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLST WTRILVQGCHAAAELIKEVSLGCT---------LNGQEVRLTVHYENGFTI----SKE----------------NGGSSS ILYRYPFERLKMSADDGIRNLYLDFGG------PEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Gallus_gallus_SNTB2 ---------------------------------------------------------MGTREAPSAPPLAALTANSVPPC GRGARPRVGARGGAERRGGGGGMAVWTRASKAGLLELLLRERWVRVAAELSGEALSLTAE---------PG--------E PTPGLNGVANGGG--------GGEWGG-----------------------------------------------AEAAVP GCVRRVRVVKAEAGGLGISIKGGREN--RMPVLISRIFPGLAAERSGALRLGDAILAVNGVDLRDATHDQAVQALKRAGR EVILEVKF----------------------------------------------------MREVTPYMKK-----PSLVS DLPWEGAAPQSPSLSG-------SEDSGSPQ----------HHG-ARDRKVIPLKMCFAARNLS---MPDLENRLIELHS PDS-RNTLILRCKDTATAHSWFTALHANIMALLPQVLAE-LNAALGG--SAGG-REVKHVAWLAEQAR------------ ------------------------LDGGRQQWRPVLMA---VTEKDLLLYDAMPWTRDAWASPCHSYPLVATRYRDGDSC GSHPHTWDAAPTSPPLPRLVHS--------------GSG----RRSPSLGSELTFATRTGSRQGIEMHVFRVETHRDLSC WTRVLVQGCHAAAELIKEVSVGCT---------LGGQEVKLCIHYEGGFTI----CRDE---------------AGGS-- VLYRYPYEKLKMSADDGIRTLYLDFGG------PEGELALDLHSCPKPIVFVLHTFLSAKVTRMGLLV------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Danio_rerio_SNTB2_a -------------------------------------------------------------------------------- ---------------------MMAVWTRAEKQGHLDLLLSDRWVRVSAELTRDNLTLTAEGEPGGPAGYPE--------H NSHLKNGVSNGNEQNRDVFTNRVQYDNSPGRVN---------------------------------GTGSDSESSGYCDS EGVRRVRIVKQESGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRVGDAILSVNGSDLRDATHDAAVQALKKAGK EVTLEVKY----------------------------------------------------IREVSPLFKK-----SSMSA DLSWDG-RLQSPNLSS-------SDE--SPK-----------SSVSRDRKVIPLKMSFISRNLT---MPDPENRLLELHS PDG-QHTVVLRCKDGATAHSWFTAIHTNVAALLPQTLSY-INTFLNNAN---THCTLKHIGWLVEQLD------------ ------------------------MDGSRHQYKRVIMA---LTEKDILLFQAVPWTYESWTTPVLTHPLLAT-------- -----------------RLVHS--------------GSV----RSSPALGGDLLFATRTGTGRGIESHVFRVETHWDLST WTRALVQGGHSAAELIKEVSIGCV---------LNRQNVRLILHYERGFTV----TRE------------------SGDS VLFHFPYERLKMSADDGVRNLFLDFGA------PEGEMVFELHSGPKPVVFVLHSFLSAKLARLGLLT------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Takifugu_rubripes_SNTB2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------QAVPILEGSS EAVRKVRVVKQESGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRVGDAILSVNGSDLREATHDLAVQALKKAGK EVTLEVKY----------------------------------------------------IREVSPLFKK-----PSLVA DLPWDGVRPQSPSYSG-------SEDSGSPKHS--------SSSSSKDRKVISLKMCFISRNLT---MPDLENRLLELHS PDG-QHTVVLRCKDAPTANSWFTAVHTNIAALLPQVLAH-INAYLGASSSAPTHPHLKHIGWLAEQIQ------------ ------------------------LDGGRQQYKPVVMA---LTEKDILLFEAVPWSRESWSLPLLTHPLLAT-------- -----------------RLVHS--------------GSA----RGSPAQGSELVFATRTGTGRGIESHVFRVETHWDLSS WTRALVQGAHAAAELIKEVSIGCT---------LNRQDVRLTLHYEKGFTV----TREPA--------------DLTGGA VLYRYPYEKLKMSADDGIRNLYLDFGG------PEGEMVFDLHSGPKPVVFVLHSFLSAKLTRMGLLT------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Tetraodon_nigroviridis_SNTB2_a -------------------------------------------------------------------------------- ----------------------MAVWTRADKNGQLDLLLRDRWIRVAAELTRETLTLTAEAEAGG---HHH--------C ANSPGKYPNNGSNSDFGSPGSSYGSPGSSFG-----------------------------------SRHGDFPLALEGSS EAVRKVRVVKQESGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRVGDAILSVNGNDLREATHDLAVQALKKAGK EVTLEVKY----------------------------------------------------IREVSPLFKK-----PSLVA DLPWDGVRPQSPSYSG-------SEDSGSPKHG--------GSSPSKDRKVISLKMCFISRNLT---MPDLENRLLELHS PDG-QHTVVLRCKDAPTANSWFTAMHTNIAALLPQVLAH-INAYLGASVSASTHPHLKHIGWLAEQIQ------------ ------------------------LEGGRQQYKPVVMA---LTEKDILLFESVPWSRESWSLPLLTHPLLAT-------- -----------------RLVHS--------------GSA----RGSPAQGSELVFATRTGTGRGIESHVFRVETHWDLSS WTRALVQGAHAAAELIKEVSIGCT---------LNRQEVRLTLHYEKGFTV----TREPA--------------DLTGGA VLFRYPYEKLKMSADDGIRNLYLDFGG------PEGEMVFDLHSGPKPVVFVLHSFLSAKLTRMGLLT------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Gasterosteus_aculeatus_SNTB2_a -------------------------------------------------------------------------------- ----------PRAPPAASAGVGMAVWTRADKRGQLDLLLRDRWIRVAAELTRETLTLTAEAEATGPGGNHW--------D YNGSSAAPRNG-VPNGNEPGASPGNPARVPPS--------------------------------GPEQLQSQNQGPDGSS EAVRKVRVVKQESGGLGISIKGGREN--RMPILISKIFPGLAADQSRALRVGDAILSVNGSDLREATHDLAVQALKKAGK EVTLEVKY----------------------------------------------------IREVSPLFKK-----PSLVA DLPWDGARAQSPSCSG-------SEDSGSPKHC--------GASP-RDRKVMSLKMCFISRNLT---MPDLENRLLELHS PDG-QHTVVLRCKDGATANSWFTAVHTNVAALLPHTLAH-VNAYLGASS--PAHPHLQHIGWLAEQVQ------------ ------------------------LEGGRQQHKPVVMA---LTEKDILLFESVPWSRESWSAPLLTHPLLAT-------- -----------------RLVQC--------------RGA----RGSPPQGSDTAFVTRTGTGRGIESHVFRVETQWDLST WTRALVQGAHAAAELIKEVSIGCT---------LNRQDVRLTLHYEKGFTV----TREPA--------------DPPGGA VLFRYPYEKLKMSADDGMRNLYLDFGG------PEGEMVFDLHSGPKPVVFVLHSFLSAKLTRMGLLT------------ -------------------------------------------------------------------------------- ----------------------------------------------- >Homo_sapiens_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTAC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPG--TDLSRQNAFQVIA VDG-VCTGIIQCLSAEDCVDWLQAIATNISNLTKHNIKKINRNFPVNQQI-------VYMGWCEAREQDPLQD------- -----------------------------RVYSPTFLA--LRGS-CLYKFLAPPVTTWDWTRAEKTFSVYEIMC------ -----------------KILK------------------------DSDLLDRRKQCFTVQSESGED-LYFSVELESDLAQ WERAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSTGFICF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQATA----- ---------STAASSATTSK----AKYTT--------------------------------------------------- ----------------------------------------------- >Pan_troglodytes_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTAC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPG--TDLSRQNAFQVIA VDG-VCSGIIQCLSAEDCVDWLQAIATNISNLAKHNIKKINRNFPVNQQI-------VYMGWCEAREQDPLQD------- -----------------------------RVYSPTFLA--LRGS-CLYKFLAPPVTTWDWTRAEKTFSVYEIMC------ -----------------KILK------------------------DSDLLDRRKHCFTVQSESGED-LYFSVELESDLAQ WERAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSTGFICF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQATA----- ---------SAAASSATTSK----AKYTT--------------------------------------------------- ----------------------------------------------- >Mus_musculus_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTTC---------EETKTGVCLLQ-DGNQEPFKVRLHLARDLLMLQEQDVLCVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPVNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHARFSQYVPG--TDLSRQNAFQVVA VDG-VCSGILQCLSAEDCMDWLQAIASNISNLTKHNIKKINRNFPVNQQI-------VYMGWCEAREQESLQD------- -----------------------------RVYTPVFLA--LRGS-CLYRFLSPPVTTWDWTRAEKTFSVCEIMC------ -----------------KVLK------------------------DSDLLDRRKHCFTMQSECGED-LYFSVELESDLAQ WERAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSTGFICF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQAAT----- ---------TAAVSSASTSK----AKHLA--------------------------------------------------- ----------------------------------------------- >Canis_familiaris_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTAC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPG--TDLSRQNAFQVIA VDG-VCSGIIQCLSAEDCIDWLQAIATNISNLTKHNIKKINRNFPVNQQI-------VYMGWCEAREQDPLQD------- -----------------------------RAYSPTFLA--LRGS-CLYKFLAPPVTTWDWTRAEKTFSVYEIMC------ -----------------KILK------------------------DSDLLDRRKHCFTVQSESGED-LYFSVELDSDLAQ WERAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSTGFICF---DAATK-------------------A ILWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYLGNQTAA----- ---------STAASSSTTSR----AKYTT--------------------------------------------------- ----------------------------------------------- >Myotis_lucifugus_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTAC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLLPLLHSRFSQYVPG--TDLSRQNAFQVIA VDG-VCSGIIQCLSADDCIDWLQAIATNISNLTKHNIKKINRNFPVNQQI-------VYMGWCEAREQDPLQD------- -----------------------------SVYSPIFLA--LRGS-CLYKFLAPPVTTWDWTRAEKTFSVYEIMC------ -----------------KILK------------------------DSDLLDQRRHCFTVQSESGED-LYFSVELDCDLAQ WERAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSTGFICF---DAATK-------------------A VLWRYKFSHLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGHQATA----- ---------SAAASSATMSK----AKYTT--------------------------------------------------- ----------------------------------------------- >Monodelphis_domestica_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTSC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLLLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPTNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPG--SDLCRQNAFQVIA VDG-VCSGIIQCLSAEDCIDWLQAIATNISNLTKHNIKKINRNFPVNQQI-------VYMGWTEEREQDSLQD------- -----------------------------RKYTPKFLA--LRGS-SLYKFLAPPVTTWDWTRAEKTFSVYEIMF------ -----------------KIFK------------------------DSDLLDRRKHCFGVQSETGED-LYFSVELECDLAQ WEKAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSMGFVCF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYLGNQASAS---- --------ASTSASSAATGK----VKYTT--------------------------------------------------- ----------------------------------------------- >Taeniopygia_guttata_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTTC---------EETKTGVCLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGD EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACAP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPASPGLRWEKRWCDLRLIPLLHSRFSQYLPG--SDLCRQNAFQVIA VDG-VCSGIIQCLSAEDCIDWLQAIASNISNLTKHNIKKINRNFPVNQQI-------VYMGWTEEREQDSLQD------- -----------------------------RMYTPKFLA--LRGA-SLYKFIAPPVTTWDWTRAEKTFSVYEIMC------ -----------------KILK------------------------DSDLLDRRKHCFSVQSESGED-LYFSVELECDLTL WEKAFQTATFLEVERIQCKTYACV---------LESHLMGLTIDFSMGFVCF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLYVGSQATAS---- --------AAPTTS--GTGK----LKYST--------------------------------------------------- ----------------------------------------------- >Anolis_carolinensis_SNTG1 -------------------------------------------------------------------------------- ---------MDFRTAC---------EETKTGICLLQ-DGNQEPFKVRLHLAKDILTIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVTIRRQTVGGFGLSIKGGAE--HNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRAPAFLKLPLNEDCACIP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYLPG--SDMCRQNAFQVIA VDG-ICSGIIQCLSGEDCIDWLQAIATNISNLTKHNIKKINRNFPVNQQI-------VYMGWTEEREQDSLQD------- -----------------------------RMYTPKFLA--LRGS-SLYKFIAPPVTTWDWTRAERTFSVYEIMY------ -----------------KILK------------------------DSDLLDRRKHGFGVQSEMGED-LYFSVELESDLIL WEKAFHSATFLEVERIQCKTYACV---------LESHLMGLTIDFGMGFVCF---DAATK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNP---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPQYVGSQAAASTSVS AASTAAAAAAAGTSTLATSSGSSKLKYTT--------------------------------------------------- ----------------------------------------------- >Xenopus_tropicalis_SNTG1 -------------------------------------------------------------------------------- ---------MEFNLCIC----------AKTGICLLQ-DGNQEPFKVRLHLAKDILMIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SGERTVAIRRQTVGGFGLSIKGGSE--HNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCKHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRSPAFLKLPLNEDCSCVP CDQSS-GTSSPLCDSGLHLNYHPNNTDSLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRLSQHITG--TDLCRQNAFQVTA VDG-VGSGIIQCLLAEECIDWLQSISANISNLTKHNIKKINRNFPVNQQI-------VFLGWVEEREQDTLKD------- -----------------------------YVYSPKFLA--LRGS-SLYKFNSPPVTTWDWMRAEKKFTVYEIMC------ -----------------KIFK------------------------DSDLLDRRKHCFGVQSETGED-LYFSVELECDLLQ WEKAFQTATFLEVERIQCKTYACV---------IESHLMGLTIDFGMGFICF---DAATK-------------------A ILWKYKFSQLKGSSDDGKSKIKFLFQNQ---DTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPRFVDSQGAAS---- ---------AAVITTSCATAGVCKMKYST--------------------------------------------------- ----------------------------------------------- >Danio_rerio_SNTG1_a -------------------------------------------------------------------------------- --------------------------QTKTGIYLLQ-DGSEEPFNIRLHLAKDILTIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SSERTVTIRRQTIGGFGLSIKGGAE--HKIPVVISKISKEQKAELSGLLFIGDGILQINGINVRSYRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKRTPAFLKLPLCEDCSCIP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPMSPGLRWEKRWVDLRLIPLLHARLSQYVPG--TDICRQNAFQVIA VDG-VCSGVIQCPGTDECTDWLQAISANISALTKHNVHLTLKCRLPGDTI-------IYMGWVDEKEQDSVQD------- -----------------------------RMYTPKFLA--LRGS-SLFKFSAPPVTTWDWTRAEKSFTVYEIMF------ -----------------KILKFY---LISSYFQVYFIYVR---VQDSELLDKRKHCFSVQTDSGED-IFFSVELECELLL WEKAFQMATFFEVERIQCKTYACI---------VDSHLMGLTIDFSMGFVCF---DAASK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---DTKLIEAKELEFSNLFAVLHCIHAFFAAKVACLDPMFVSSRNAAM---- ---------APVVSA----------------------------------------------------------------- ----------------------------------------------- >Takifugu_rubripes_SNTG1_a -------------------------------------------------------------------------------- ---------MDFKTSNEE---------TKTGIYLMQ-EGNEEPFNIRLHLAKDILTIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SSERTVTIRRQTIGGFGLSIKGGAE--HKIPVVISKISKEQKAELSGLLFIGDGILQINGINVRSYRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKKTPAFLKLPLCEDCTCIP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPALRWEKRWVDLRLIPLLHSRLSRYSPG--SDSCRKNAFQVIA VDG-VCSGVVQFPTAEDCLDWLQAISGNISSLTKHNVKKINRNFPVNQQI-------IYMGWVDEKEQDSVQD------- -----------------------------RMYSPKFLA--LRGS-SLFKFSAPPVTTWDWTRAEKSFTLYEIMF------ -----------------KILK------------------------DNDLLDKRRHCFSVQTESGED-MFFSVELDCELLI WEKAFQTATFLEVERIQCKTYACI---------MESHLMGLTVDFGMGFVCF---DAASK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---DSKSIEAKELEFSNLFAVLHCIHAFFAAKVACLDPMFVESQGTAT---- ---------TAGFPSLSAIS----SKHLS--------------------------------------------------- ----------------------------------------------- >Tetraodon_nigroviridis_SNTG1_a -------------------------------------------------------------------------------- ---------MDFKTSNEE---------TKTGIYLMQ-EGNEEPFNIRLHLARDILTIQEQDVICLSGEPF---------- -------------------------------------------------------------------------------Y SSERTVTIRRQTIGGFGLSIKGGAE--HKIPVVISKISKEQKAELSGLLFIGDGILQINGINVRSYRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKKTPAFLKLPLCEDCTCIP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPALRWEKRWVDLRLIPLLHSRLSRYSPG--SDSCRKNAFQVIA MDG-VCSGVVQFATAEDCLDWLQAISSNISSLTKHNVKKINRNFPVNQQI-------IYMGWADEKEQDSVQD------- -----------------------------RMYSPKFLA--LRGS-SLFKFSAPPVTTWDWTRAEKSFTVYEIMF------ -----------------KILK------------------------DNDLLDKRKHCFSVQTESGED-MFFSVELDCELLI WEKAFQTATFLEVERIQCKTYACI---------MESHLMGLTVDFTMGFVCF---DAASK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---DSKSIEAKELEFSNLFAVLHCIHAFFAAKVACLDPMFVESQGTAT---- ---------TAGFPSLSAIS----CHSQT--------------------------------------------------- ----------------------------------------------- >Gasterosteus_aculeatus_SNTG1_a -------------------------------------------------------------------------------- ---------MDFKTS---------NEETKTGIYLMQ-EGNEEPFNIRLHLARDILTIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SSERTVTIRRQTIGGFGLSIKGGAE--HKIPVVISKISKEQKAELSGLLFIGDGILQINGINVRSYRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKKTPAFLKLPLCEDCTCVP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPACPGLRWEKRWVDLRLIPLLHSRLSQYNPG--SDVCRKNAFQVIA VDG-VCSGVLQFLTADDCLDWLQALASNISSLTKHNVKKINRNFPVNQQI-------IYMGWVDEKEQDSVQD------- -----------------------------RMYSPKFLA--LRGS-SLFKFSAPPVTTWDWTRAEKSFTVYEIMC------ -----------------KILK------------------------DNDLLDKRKHCFGVQTESGED-LFFSVELECELLI WEKAFQMATFLEVERIQCKTYACI---------MESHLMGLTVDFGAGFVCF---DAASK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---DSKSIEAKELEFSNLFAVLHCIHAFFAAKVACLDPIFVESQGNAT---- ---------PAGFPSLCSIS----CNSQTPKLKYAT-------------------------------------------- ----------------------------------------------- >Oryzias_latipes_SNTG1_a -------------------------------------------------------------------------------- --------TSFFPTWNCS--------QTKTGIYLMQ-EGNEEPFNVRLHLAKDILTIQEQDVICVSGEPF---------- -------------------------------------------------------------------------------Y SSERTVTIRRQTIGGFGLSIKGGAE--HKIPVVISKISKEQKAELSGLLFIGDGILQINGINVRSYRHEEVVQVLRNAGE EVTLTVSF----------------------------------------------------LKKTPAFLKLPLCEDCTCIP SDQSS-GTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSTGLRWEKRWVDLRLIPLLHSHLSQYMPG--SDTCRKNAFQVIA VDG-VCSGVLQFPTAEDCLDWLHAIASNISSLTKHNVKKINRNFPVNQQI-------IYMGWVDEKEQDSVQD------- -----------------------------RMYTPKFLA--LRGS-SLFKFTAPPVTTWDWTRAEKSFTVYEIMS------ -----------------KILKVRLSLCVIIQFPPHFKERL---SQENDLLDKRRHCFSVQTESGED-MFFSVELECDLLV WEKAFQMATFLEVERIQSKTYACI---------MESHLMGLTIDFSMGFVCF---DAASK-------------------A VLWRYKFSQLKGSSDDGKSKIKFLFQNQ---ESKSIEAKELEFSNLFAVLHCIHAFFAAKVACLDPVFLESQGTAA---- ---------NAGIPS----------------------------------------------------------------- ----------------------------------------------- >Homo_sapiens_SNTG2 -------------------------------------------------------------------------------- ---MGTEGPPPPAASRGRQGCLLVPARTKTTIALLYDEESENAYDIRLKLTKEVLTIQKQDVVCVGGSHQ---------- -------------------------------------------------------------------------------G RNRRTVTLRRQPVGGLGLSIKGGSE--HNVPVVISKIFEDQAADQTGMLFVGDAVLQVNGIHVENATHEEVVHLLRNAGD EVTITVEY----------------------------------------------------LREAPAFLKLPL--GSPGPS SDHSS-GASSPLFDSGLHLNGNSSTT-APSSPSSPIAKDPRYEKRWLDTLSVPLSMARISRYKAG--TEKLRWNAFEVLA LDG-VSSGILRFYTAQDGTDWLRAVSANIRELTLQNMKMANKCCSPSDQV-------VHMGWVNEKLQGADSS------- -----------------------------QTFRPKFLA--LKGP-SFYVFSTPPVSTFDWVRAERTYHLCEVLF------ -----------------KVHKFWLTEDCWLQANLYLGL------QDFDFEDQRPYCFSIVAGHGKS-HVFNVELGSELAM WEKSFQRATFMEVQRTGSRTYMCS---------WQGEMLCFTVDFALGFTCF---ESKTK-------------------N VLWRFKFSQLKGSSDDGKTRVKLLFQNL---DTKQIETKELEFQDLRAVLHCIHSFIAAKVASVDPGFMDSQSLAR---- ---------KYMYSS----------------------------------------------------------------- ----------------------------------------------- >Pan_troglodytes_SNTG2 -------------------------------------------------------------------------------- ---MGTEGPPPPAASRGRQGCLLVPARTKTTIALLYDEESENAYDIRLKLTKEVLTIQKQDVVCVGGSHQ---------- -------------------------------------------------------------------------------G RNHRTVRLRRQPVGGLGLSIKGGSE--HNVPVVISKIFKDQAADQTGMLFVGDAVLQVNGIHVENATHEEVVHLLRNAGD EVTITVEY----------------------------------------------------LREAPAFLKLPL--GSPGPS SDHSS-GASSPLFDSGLHLNGNSSTT-APSSPSSPIAKDPRYEKRWLDTLSVPLSMARISRYKAG--TEKLRWNAFEVLA LDG-VSSGILQFYTAQDGTDWLRAVSANIRELTLQNMKMANKCCSPSDQV-------VHMGWVNEKLQGADSS------- -----------------------------QTFRPKFLA--LKGP-SFYVFSTPPVSTFDWVRAERTYHLCEVLF------ -----------------KVHKFWLTEDCWLQANLYLGL------QDFDFEDQRPYCFSVVAGHGKS-HVFNVELGSELAV WEKSFQRATFMEVQRTGSRTYMCS---------WQGEMLCFTVDFALGFTCF---ESQTK-------------------N VLWRFKFSQLKGSSDDGKTRVKLLFQNL---DTKQIETKELEFQDLMAVLHCIHSFIAAKVASVDPGFMDSQSLAR---- ---------KYMYSS----------------------------------------------------------------- ----------------------------------------------- >Callithrix_jacchus_SNTG2 -------------------------------------------------------------------------------- -----------PAAPRGRQGCLLVLARLKTAVALLYSEEYHSAYDIRLKLTKEMLTIQKQDVICVGGSHQ---------- -------------------------------------------------------------------------------G RSHRTVTLRRQPVGGLGLSIKGGSE--HNVPVVISKIIKGQAADQTGMLFVGDAVLQVNGINVENATHEEVVHLLRNAGD EVTITVEY----------------------------------------------------LREAPAFLKLPL--GSPGPS SDHSS-GASSPLFDSALHLNGNSRNT-APSSPSSPIAKDPRYEKRWLDALSVPLSMARISRYKAG--TEKFRWNAFEVLA LDG-VSSGILQFYTAQDGADWLRAVSANIRELTLQNMKLANRCCSASDQV-------VHMGWVHEKLHGADSS------- -----------------------------QTCRPKFLA--LKGP-SFYVFSSPPVSTFDWVRAERTYYLCEVLF------ -----------------KVHKFWLTDDCWLQANLYLGL------QDGDFEDQRPYCFSVVAGHGKS-HVFSVELGSELAV WEKSFQRAMFMEVQRSGSKTYACS---------WQGEMLCFTVDFALGFTCF---ESKTK-------------------N VLWRFKFSQLKGSSDDGKTRVKLLFQHL---DTKQIETKELEFQDLTAVLHCIHAFIAAKVASVDPGFVDSQSLAK---- ---------KYMYSN----------------------------------------------------------------- ----------------------------------------------- >Mus_musculus_SNTG2 -------------------------------------------------------------------------------- ---MSAEGSQSLAAPRGRPSHLLVPARTKTALALLYDEGLENAYDVRLKLTKEVLTIQKQDVVCIGGAPP---------- -------------------------------------------------------------------------------G ANHRTVTLRRQPVGGLGLSIKGGAE--HGVPVVISKIFKDQAADQTEMLFIGDAVLQVNGINVENATHEEVVHLLRNAGD DVTITVEY----------------------------------------------------LREAPSFLKLPL--GSPGPS SDHSS-RASSPLFDSGLHLNGHCSHT-APSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKAG--TEKLRSSALEVLA LDG-ASTGVLQFSTAQDCADWLRSISTNISDLTLQHMKMANKCCSPCDQV-------VHMGWVNERLQGADNS------- -----------------------------QNFRPKFLA--LRGS-SFYIFGAPPVSTLDWGRAERAYNLCEVLF------ -----------------KVHKFWLSDNYWLQANLYLGL------QDFDCEDPRSYCFSVLANHGKS-HIFSVELGSELAV WEKAFQRATFMEVQRTGSKTYLCS---------WQGETLCFTVDFALGFTCF---DGKTK-------------------N VLWRFKFSQLKGSSDDGKTRVKLLFQNL---DTKQIETKELEFQDLTAVLHCIHSFIAAKVASLDPVFMDSQSMAR---- ---------RYLCSS----------------------------------------------------------------- ----------------------------------------------- >Felis_catus_SNTG2 -------------------------------------------------------------------------------- -ARGRGPVVAPTSLRSRPWPVSALPPQTRTGLALLHHEGSGSPCDVRLKLTREVLTIQKQDVVCVRGSSH---------- -------------------------------------------------------------------------------G AHHRTVTLRRQPVGGLGLSVKGGAE--HRVPVVISKIFRGHAADQTGMLFVGDAVLQVNGINVEHATHEEVVHLLRNAGD EVAITVDY----------------------------------------------------LREAPAFLKLPL--GSPGPA GDHSS-GASSPLFDSGLHLNSNPSST-DSPSPSSPAADAPQYEKRWLDTLSVPLSMARISRCKAG--TGKCRSGAFQVLA VDG-VRTGVLQFHTARESADWLRAVSATISDLTLESMKMVNEGCSPCDQV-------VHMGWVRERLEGTSSR------- -----------------------------ETFRSKFLA--LKGS-LLYVFSTAPVSTLDWVRAEKTYNLCEVLF------ -----------------KLHKLWLADDGWLHEACHLGP--------PGFAPQRPFSFSVLVGHGQS-RVFSVDLGSELAA WERSFQRATFKEVQRSRSKTYTCS---------WQGEMLCFTVDFALGFTCS---DSKTK-------------------N VLWRFKFSQLKGSSDDGNARVKLLFQHP---DTKQIEVKELEFPDLTAVLHCVHAFLAAKVASVDPAFMDSQSFAR---- ---------KSASAE----------------------------------------------------------------- ----------------------------------------------- >Monodelphis_domestica_SNTG2 -------------------------------------------------------------------------------- -----SQGPPPPASFRLLIGCILVPLLTKTGIALLYDEGSENAFDIRLKLTKEVLTIQKQDVVCVSGSNH---------- -------------------------------------------------------------------------------S TNHRTVTLHRQPVGGLGLSIKGGAE--HKVPVVISKIFKDQAADQTGMLFIGDAVIQVNGINVENATHEEVVHLLRNAGD EVTITVQY----------------------------------------------------LREAPSFLKLPL--GSPGPS SDHSS-GASSPLFDSGLHLNGNSSNT-APSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKAG--TDKLRSNAFEVLA LDG-VSTGIIQFYTSQESADWLRAVSTNIGDLTLQNMKMANKCCSPCDQV-------VHMGWVNERIQGIDSS------- -----------------------------QPYKYKFLA--LKGS-SFYIFSTPPVSTLDWVRAEKIYNLCEVLF------ -----------------KVHKLWLADDCWLQANFYLGLH-----QDYDLEDQRPYCFSVMVGQGKS-HFFNVELGSELAV WEKSFQRAIFMEVQRTGSKTYMCS---------WQGEALCFTVDFALGFTCF---DSKTK-------------------N VLWRFKFSQLKGSSDDGKTRVKLLFQNL---DTKQIEMKELEFQDLTAILHCIHSFIAAKVASVDPMFIDSQSIAR---- ---------RYMYSN----------------------------------------------------------------- ----------------------------------------------- >Gallus_gallus_SNTG2 -------------------------------------------------------------------------------- ---VMYMGITGLSLERAEPHELLIPDRTKTGIALLYDEVSENAYDIRLKLTKEVLTIQKQDVICVSGSDR---------- -------------------------------------------------------------------------------S ANHRTVTLHRQPVGGLGLSIKGGAE--HKVPVVISKMFKDQAADQTGMLFIGDAITQVNGINVESATHEEVVHLLRNAGD EVTITVQY----------------------------------------------------LREAPSFLKLPL--GSPGPS SDHSS-GASSPLFDSGLHLNGNSANT-APSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKTG--TDKLRSNAFEVLA LDG-VSTGILQFYTAQESADWLRAISTNISDLTLQNMKMANKCSSPSDQV-------VHMGWVHERLEGTDSS------- -----------------------------QLYKFKFLA--LKGS-SFYIFSTPPVSTLDWVRAEKMYNLCEVLF------ -----------------KIHKLWLADDCWLQANLYFGIH-----QDFDFEDHRPYCFSVMVGHGKS-HCFNVELGSELAV WEKSFQRAIFLEVQRTGSKTYMCS---------WQGDTLCFTVDFALGFTCF---DSKTK-------------------N VLWRFKFSQLKGSSDDGKTKVKLLFQNP---DTKQIETKELEFQDLTAVLHCIHSFIAAKVASVDPVFIDSQSIAR---- ---------KYMYSN----------------------------------------------------------------- ----------------------------------------------- >Pelodiscus_sinensis_SNTG2 -------------------------------------------------------------------------------- --------------------------QTKTGIALLYDEGSENAYDIQLKLTKEVLTIQKQDVICVSGSDH---------- -------------------------------------------------------------------------------S TNHRTVTLHRQPVGGLGLSIKGGAE--HKVPVVISKIFKDKAADQTGMLFIGDALLQVNGINVESATHEEVVHLLRNAGD EVTITVQY----------------------------------------------------LREAPSFLKLPL--GSPGPS SDHSS-GASSPLFDSGLHLNGNTTNT-APSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKAG--TDKLRSNAFEVLA LDG-VSTGILQFYTAQESADWLRALATNISDLTLQNMKMANKCCSLSDQV-------IHMGWVNERLEGTDSS------- -----------------------------QLYKYKFLA--LKGS-SFYIFSTPPVSTLDWIRAEKIYHLCEVLF------ -----------------KVHKLWLADDCWLQANLYLGIH-----QDYAFEDQRPYCFSVMVGHGKS-HSFNVELGSELVA WEKSFQRAIFLEVQRTGSKTYMCS---------WQGVALCFTVDFALGFTCF---DSKTK-------------------N VLWRFKFSQLKGSSDDGKTKVKLLFQNI---DTKQIEMKELEFQDLTAVLHCIHSFIAAKVASLDPVFIDSQSIAR---- ---------KYMYSN----------------------------------------------------------------- ----------------------------------------------- >Danio_rerio_SNTG2_a -------------------------------------------------------------------------------- ---MNAAAKHQPDLLERPASLLVPTW-TKTGLALLYDEHTSNTYDVRLKLTKDLLIIQKQDVVCASGIES---------- -------------------------------------------------------------------------------H LNHRTVVLRRQATGGLGLSIKGGAE--HKVPVVISKIFKDQVADQTGKLFIGDAVLQVNGINVEKCTHEEVVHLLRTAGD EVSITVRY----------------------------------------------------LREAPAFLKLPL--GSPGPS SDHSS-RASSPLFDSGLHLNGNSSNT-APSSPSSPSANEPKYEKRWLDAVTLPLFMARISRRKAG--TDKLRSNSFEVIA LDG-VCTHVLQFCTAGESTDWLQAISTNINDLTQDSIKTVNKYCSADDQV-------DCPHGLGVRADSRRRC------- -----------------------------RQRRRRRSL--LQIPGAQRISSAYLQDSTYWTQAEASFHLCEVLF------ -----------------KVHKLWIAEDCWIQTKLYMGLQ-----QDGELRDSEPFCFSVLLGHGQS-FCFSVELGSDLVL WEKAFQRAVFMEVQRVRSKSYMCS---------SQGKILCFTIDFESGFSCS---DTLSK-------------------K IIWKYKFSQLKGSSDDGKTRVKLLFQNS---ENKQIEMKELEFANLTAVLHCIHSFIAAKVATVDPVFVSNQSLTQ---- ---------KYMCSS----------------------------------------------------------------- ----------------------------------------------- >Tetraodon_nigroviridis_SNTG2_a -------------------------------------------------------------------------------- --AAQITFSFADPRHDPSHRVKLLTIKTKSGIALLYKEETNNSYDVCLKLTKEVLTIQKLDVVCTNGPET---------- -------------------------------------------------------------------------------Q VNHRTVVLRRQANGGLGLSIKGGAE--HNVPVVISKIFKDQVADQTGKLFVGDAVLQVNGIHVELCTHKEVVHLLRTAGD EVTITVRY----------------------------------------------------LREVPSFLKLPL--GSPGPS TDHS