>Homo_sapiens_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHGVTCD----SACDSL-SHHSDR---KPYLLSPVEH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYTS-----QQELKDEC--ALVPRTLAT-------------KA NRIPANLLDQFER-QLPLSRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GGKASPDE-------AQAARYGKRSKSKERRA---------E PK--------------ARPSTS------PGWWSSDDNLDGDMCIYHAP---------------SGVMTMGR----CPDRS ASQ--------------------YFLEAYNTISEQ--AVKASRSNNDVKCSTCAN-------------LPVS-------- -LDTPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------MDQAMVKSE--SCQQERSCQY- -LQ------------------------------------VPQDE-WTGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGNNTATVT-TTTTI------- -------ATVTTEDRKKDHFKK-----NRCLSIGIQVDDAE----------------EPDKTGENKAPSKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPMAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDTDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Pan_troglodytes_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHGVTCD----SACDSL-SHHSDR---KPYLLSPVEH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYTS-----QQELKDEC--ALVPRTLAT-------------KA NRIPANLLDQFER-QLPLSRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GGKASPDE-------AQAARYGKRSKSKERRA---------E PK--------------ARPSTS------PGWWSSDDNLDGDMCIYHAP---------------SGVMTMGR----CPDRS ASQ--------------------YFMEAYNTISEQ--AVKASRSNNDVKCSTCAN-------------LPVS-------- -LDTPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------MDQAMVKSE--SCQQERSCQY- -LQ------------------------------------VPQDE-WTGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGNNTATVT-TTTTI------- -------ATVTTEDRKKDHFKK-----NRCLSIGIQVDDAE----------------EPDKTGENKAPSKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPMAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDTDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gorilla_gorilla_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHGVTCD----SACDSL-SHHSDR---KPYLLSPVEH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYTS-----QQELKDEC--ALVPRTLAT-------------KA NRIPANLLDQFER-QLPLSRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GGKASPDE-------AQAARYGKRSKSKERRA---------E PK--------------ARPSTS------PGWWSSDDNLDGDMCIYHAP---------------SGVMTMGR----CPDRS ASQ--------------------YFMEAYNTISEQ--AVKASRSNNDVKCSTCAN-------------LPVS-------- -LDTPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------MDQAMVKSE--SCQQERSCQY- -LQ------------------------------------VPQDE-WTGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGNNTATVT-TTTTI------- -------ATVTTEDRKKDHFKK-----NRCLSIGIQVDDAE----------------EPDKTGENKAPSKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPMAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDTDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Mus_musculus_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHGITCE----AACDSL-SHHSDH---KPYLLSPVDH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYTS-----QQELKDES--ALVPRTLAT-------------KA NRLPTNLLDQFER-QLPLSRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GGKASPDE-------SQTLRYGKRSKSKERRS---------E SK--------------ARSNASNASPTSPSWWSSDDNLDGDMCLYHTP---------------SGVMTMGR----CPDRS ASQ--------------------YFMEAYNTISEQ--AVKASRSNNDIKCSTCAN-------------LPVT-------- -LDAPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------MDQAMVKSE--ACQQERSCQY- -LQ------------------------------------VPQDE-WSGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPLPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDMISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGSNAAAVT-TTTTI------- -------ATVTTEDRKKD-FKK-----NRCLSIGIQVDDAE----------------EPEKMAESKTSNKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPMAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDTDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCKLMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Rattus_norvegicus_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHGITCE----SACDSL-SHHSDH---KPYLLSPVDH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYTS-----QQELKDES--ALVPRTLAT-------------KA NRLPTNLLDQFER-QLPLSRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGGVN------------------GGKASPDG-------SQTVRYGKRSKSKERRS---------E PK--------------ARSNASNASPTSPSWWSSDDNLDGDMCLYHTP---------------SGVMTMGR----CPDRS ASQ--------------------YFMEAYNTISEQ--AVKASRSNNDVKCSTCAN-------------LPVT-------- -LDAPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------MDQAVVKSE--ACQQERSCQY- -LQ------------------------------------VPQDE-WTGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSSTGVIKLSSAVE--------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDMISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGSNAAAVT-TTTTI------- -------ATVTTEDRKKD-FKK-----NRCLSIGIQVDDAE----------------ESEKMAESKTSSKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPMAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDTDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCKQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Myotis_lucifugus_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHGVTCD----STCD---SHHSDR---KPYLLSPVEH-------HPADHP YYTQRNSFQAECVGPF-------SDPLAS--STFPRRHYNS-----QQELKDEC--ALVPRTLAT-------------KA NRLPPNLLDQFER-QLPLSRDGYHTLQYKRT----ALEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GGKASPDE-------TQTVRYGKRSKSKERRP---------E PK--------------ARPNTSPN--TSPGWWSSDDNLDSDMCIYHSP---------------SGVMTMGR----CPDRS ASQ--------------------YFMETYNTISEQ--AVKASRSNNDVKCSTCAH-------------LPVN-------- -LDAPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------VDQAMVKSE--SCQQERSCQY- -LQ------------------------------------VPQDE-WTGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKV--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPVPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSSTGVIKLSSAVE--------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGNNPATIT-TTTTI------- -------ATITTEDRKKDHFKK-----NRCLSIGIQVDDAE----------------EPDKTGENKAPSKFQSVGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHDNLENSLESIE------------------------------DNSCP-- GPAAR--QFSRDASTSTVSIQGSGNHYHACAADDD-------FDADFDPSILPPPDP-----WIDS-------------- ITEDPMEA---VQRS----VCHRDGHWFLKLLQAERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRAPPPVPKKPAKG----------------------PAPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAARRRRV----------------TR---ATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Monodelphis_domestica_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHGVTCD----SACDSL-SHHSDR---KPYLLSPVEP-------HPADHP YYTQRNSFQAECVVPF-------NDPLAS--STFPRRHYNS-----QQELKEEC--ALVPRTLAN-------------KA NRLPPNLLDQFER-QLPLNRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSIN------------------GGKASPDD-------TQTMRYGKRSKSKERRP---------E PK--------------ARSNAS-------GWWSSDDNLDGDVCLYHAP---------------SAVMTMGR----CPDRS ASQ--------------------YFMEAYNTINEH--AVKASRSNNDVKCSTCAN-------------LPVT-------- -LDAPLLK----KSAWSSTLTVSRAREVYQK-------------ASVN----------VDQALVKAE--TCQQERSCQY- -LQ------------------------------------VPQDE-WSGYTPRGGKDDE--------IPCRRMRSGSYIKA MGD--EDSGDSDT-SPKPSPKI--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECVS-------LRSSSPPRTTTTVRTI QSSTGIIKLSSAVE--------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGQ-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMGSNTATASTTTTTT------- -------ATVTAEERKKDHFKK-----NRCLSIGIQVDDVD----------------EPVKAGENKVTSKFQSIGVQVEE EKCFRR--------FTRSNSVTAAVQADLDFHENLENSLESIE------------------------------DNTCP-- GPMSR--QFSRDASTSTA-------------------------------------------------------------- ----------------------------------ERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PLDKK-------E-RRVPPPVPKKPAKG----------------------HVPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gallus_gallus_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHGVTCD----PPCDSL-SHHSDR---KPYLLNPVDP-------HPADHP YYTQRNSFQAECMVPY-------NDQIAS--STFPRRHYNS-----HHELKDEC--ALVPHGTAN-------------KT NRIPANLLDQFER-QLPLNRDGYHTLQYKRT----AMEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSVN------------------GSKASPEE-------SQTMRYGKRSKSKERRS---------E GK--------------PRSNAS-------GWWSSDDNLDNDVCIYHGP---------------SGVMTMGR----CPDRS SSQ--------------------YFMEAYNTISEH--TVKSSRSNNDVKCSTCAN-------------LPVN-------- -LDSQLMK----KSSWSSTLTVSRAREVYQK-------------ASVN----------MDQTVVKAE--TCQQERSCQY- -LQ------------------------------------VPQDE-WSGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--DDSGDSDT-SPKPSPKI--AARR----------------------ESYLKATQPSLTELTTLKISSE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECIS-------LRSSSPPRTTTTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGH-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHVGNNTATVT-TTTTI------- -------ATVAVEDRKKDHFKK-----NRCLSIGIQVDGAE----------------ETAKPGENKATSKFQSIGVQVEE EKCFRR--------FTRSNSVTTAVQADLDFHENFEI-IDPQE------------------------------DNLCS-- GQISR--QFSRDASTSTVSIQGSGNHYHACAVDDD-------FETDFDPSILPPPDP-----WIDS-------------- ITEDPLEA---VQRS----VCPRDGHWFLKLLQAERDRMEGWCQQMEREEREN-------------------NLPEDILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PHDKK-------E-RRVPPPVPKKPSKG----------------------QVPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Anolis_carolinensis_DLGAP1 -------------------------------------------------------------------------------- ---------MMKGL-SGSRSH---------HHGVVYE----PPCDSL-VHHSER---KPYLLNPVDH-------HPSDHS YYTQRNSFQGECMVPY-------NDQIAS--STFPRRHYNS-----HNELKDEC--ALVPHGSAG-------------KG NRIPANLLDQFER-QLPLNRDGYHTLQYKRT----AVEHR-------------SDSPGR-------IRHLVHSVQKLF-T KSHSLEGPS------KGSIN------------------GGKASPEE-------TQSMRYGKRSKSKDRRS---------E GK--------------SRSNAS-------GWWSSDDNLDNDVCLYHGP---------------SGVMTMGR----CPDRS ASQ--------------------YFMEAYNTLSEH--AVKPSRSNNDVKCSTCAN-------------LPVT-------- -LDAPLMK----KSSWSSTLTVSRAREVYQK-------------ASMN----------MDQTMMKSE--TCQQERSCQY- -LQ------------------------------------VPQDE-WSGYTPRG-KDDE--------IPCRRMRSGSYIKA MGD--DDSGDSDT-SPKLSPKI--AARR----------------------ESYLKATQPSLTELTTLKISSE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-ECLS-------LRSSSPPRTTTTVRTI QSSTDLLDPVSHYDCKMILTNHRPQNKDASRRKLVSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGH-GQRGDIISQS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHIGNNTTTVT-TTTTV------- -------ATVTADDRKRDHYKK-----NRCLSIGIQVDGED----------------SSS-SSETRTPSKFQSIGVQVEE EKCFRR--------FTRSNSVTTAVQADMDFHENFEMSMDPQE------------------------------DLSYP-- GQMSR--QYSRDASTSTVSIQGSGNHYHACTVDDD-------FDTEFDPSILPPPDP-----WIDS-------------- IIEDPIEA---VQRS----VCPRDGHWFLKLLQAERERMEGWCQQMEREERET-------------------HLPDEILG KIR-TAVGSAQLLMAQKFYQFRELCEENLNPNAH----------P--RPASQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKQMD-----PHDKK-------E-RRAPPPVPKKPSKG----------------------QVPLIR------------ --------ERSLESSQ-----------RQ--EARKRLMAAKRAAS----------------VRQNSATESAESIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Xenopus_tropicalis_DLGAP1 -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHGVVCD----SVCETL-PHHTDR---KPYLLNPVDP-------HPADHP YYAQRNSYPVDHMISY-------GDQIAS--STFPRRHYSS-----HHDIKDDC--ALVPHGSVG-------------KG NRLPSSLLDQFER-QIPINRDGYHTLQYKRS----AVEHR-------------SDSPGR-------IRHLVHSVQRLF-T KSHSLEGPM------KGNAN------------------GNKANSDE-------MQTVRYGKRSKSKERRA---------E VK--------------PRANIQ-------GWWGSQDNLDNDVCIYHGP---------------STVMTMGR----CPDRS TSQ--------------------YFMEAYNTINDH--ALKSSRSNNDVKCNTCTN-------------LPVS-------- -LDSQMLK----KSSWASSLTVSRAREVYQK-------------PAIN----------MDQALVKSESMTQPQERPCQY- -LQ------------------------------------VPQDE-WSGYSPKS-KDDE--------IPCRRMRSGSYIKA MGD--DDSGDSDTNSPKPSPKI--AARR----------------------ESYLKATQPSLTELTTLKISNE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSMDSLDP------AALLTSPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEMEVNGQFES--VCESVFSELES----QA VEALD--------------------LPMPGCFRMRSHSYVR-AIEKGCSQDD-DSLL-------LRPSSPPRTATTVRTI QSST------------------------------VSSCITT------YKKTPPPVPPRT-----TTKPFISITAQSSTES AQDAY----MDGH-GQRGDMISHS-------------------------------------------------------- -------GLSNSTESLDSMKALTAAIEAAN------------------AQIHGPASQHMDN-TTTVNSTATTT------- -------AIINEDDRRKNHFRK-----N--LSIGIQVDGPE----------------EAARAEERQAAFRYQSVGIQVEE ERALRR--------LTRSNSVTAAVQADLDLREHFECPVELADQ-----------------------------EFQFS-- RPLAK--QYSRDACTSTVSIQGSGNHYHACAVEED-------FDADFDPSILPPPDP-----WIDS-------------- ITEDPMEA---VHRS----VCHRDGHWFLKLLQAEKDRMEGWCQQMKREEHEN-------------------DLPDPILD KIR-SAVGCAQLLMSQKFYQFRELCEENLNPNAH----------P--RPTSQDLAGFWDMLQLSIENISMKFDELHQLKA NNWKKMD-----SLDKK-------D-KRAPPPVPKKPSKG----------------------QAPLVR------------ --------DRSLESSE-----------RQRHEARKRLMSAKRAAS----------------VRQNSATESADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Danio_rerio_DLGAP1_a -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHVVT-CD---PSFESM-GHHLDH---KPYLISQIDN------PHPVDHS YY--SQRSPYQPD-----------CVVPY--GTFPRRHYSS-----QHELKDE-M-AVVPYSGGGVPAS--------KGQ QRLPVALLDQFDR-QLPVPRDGYHTLQYKRAA---AALEQ------------RSDSPGR-------IRHLVHSVQKLF-T KSHSLEGPHHGHGHGKGSIN------------------GGKASPDG----EPP--AIRHRKRSKSRERCKS-------AE PKNR--------------TPPS-------GYWSSDE-LEREACLFH---HGP-----------PGVMTMGR----HPDKS QSQ--------------------YFLEAYNTIND--QALKNSRSNNDLGKCSTCT----------SIP-LSV-------- -DASQLVK----KSSWSSSLTVSRARQVYQK-------------ASVN----------VDKALVKAEA-CQ-QERSCQF- -LQLWK--CVFVELSVCLDADMH-VWAKVCDVASLLNRQVPQDE-WGGF-PLG-KDED--------IPCRRMRSGSYVKA MAE--DDSGDSDG-SPKPSPKM--QARR----------------------ASYLKATQPSLTEMTTLKISQE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDTLDP------KALLASPQYR---- ---------SRNESYMRAMSTIS----------------------------------QIEA--MCESVFNEMES----HA VDALD--------------------LPMPGCFRMRSHSYVR-AIDQGCSQD-------DDSP-LLPASPPRT-TTTVRTI QS------------------------------STVSSCITT------YKKTPPPVPPRT-----STKPFISITAQSSTES AQDAY----MDGP-GTRGEPVLHS-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQIHGPASQHVSNSTMTISTAPPSPLPLP--- VPVPVPIPIPALEDVRRDVLRK-----SRCLSIGIQS--------------------------------KFQSVGVQVEE EHG-----------------VTTAVQADLDTPDY--TPADSPVT-----------------------------D--FPAA GCLSR--QYSRDAATSTVSIQGSGNHYHACTSDDY-------EDVGFDPSILPPPDP-----WIDS-------------- VIEDSLEV---VGRS----VCQRDGRWFLKLLQAETERMEGWCRQMEHDEKEN-------------------KMPDEVLG KIR-GAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPVAQDLAGFWDMLQLSIENISLKFDELHQLKA NNWRPLD-----PPERK-------E-RRLPPPVPKKPPK----------------------AHPPLAR------------ --------DRSLESTE-----------KQRQEARKRLMAAKRAAS----------------VRQNSATESADSIEIYIP- ---------------------------------------------EAQTR------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Takifugu_rubripes_DLGAP1_a -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHGVT-CD---PSYDSMTLGHPDR---RPYFLNPGEA-------HPADHP FYTQHNSCPSESST---------YPDLAS--CTFPRRHFSS-----HHELKEECG-ALVPYTGPTGSR----------SN NRVSSAVLEQFDR-QAPVRREGYHTLQYKRT----AVEHQ------------RSDSPGR-------IRHLVHSVQKLF-T KSHSLEGPSGSGGGGSGRVN------------------GCKSSPDDP---PSTSGTLKHSKRSKSKDRSK--------SE PK--------------MRTAIS-------GYWSSDDTLDRDACLYHHH-HGGRSGG-----LPSGVMTMGR----HPDKS QSQ-------------------YFM-ESYNTISA--HSLKTSRSNNDV-KCTTCS--AGSSG---SIPLAAG-------- -SMDGQVQ--LKKSSWSSTLTVSRAREVYQK-------------ASVN----------LDKALVKAE-----QGRTCHF- -LQ------------------------------------VPQDD-WSGFSPLG-KDDE--------IPCRRMRSGSYIKA MAE--EDSGDSDG-SPKLSPKV--QARR----------------------ASYLKATQPSLTEMTTLKISTE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLASPKFR---- ---------SRNESYMRAMSTIS-------------------------QVSEVEVNGQIEA--VCESVFSEMES----QA VDALD--------------------LPVPSCFRMRSHSYVR-AIEKGCSQEE-EEAGGGAKVGNRRTGSPPRTTTTVRTI QSSTAIMK--------------------LKIFSEVSSCITT------YKKTPPPVPPRT----TPSKPFISITAQSSTES AQDAY----MDGGSGPRAGISSQP-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQVHGPPSQHVTNSSITITATATT-------- ---SAVAHISADSKAQREALR-------KCLSIGIQVD--------------------PEEGGPTEEQSKFQSIGIQVED ERCYRR--------MTRSNSVTAAVQADLDDGT--DPPELPPRH-----------------------------F------ ATMPR--QHSRDAATSTVSIQGSGNHYHACASDDY-------GDAGFDPSILPPPDP-----WMDG-------------- AGEAEAETPEAIARS----VCPRDGRWFLKLLQAEAERMEGWCRQMEQDEREN-------------------ELPDEILG KIR-SAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPISQDLAGFWDMLQLSIENISLKFDELHQLKA NHWKPLT-----PPEIQ-------E-RRMPPPVPKKPLKG----------------------HPPLAR------------ --------DRSLESSE-----------RQRLEARKRLLAAKRAAS----------------VRQSSATESADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Tetraodon_nigroviridis_DLGAP1_a -------------------------------------------------------------------------------- ----------MKSL-SSSRSH---------HHGVT-CD---PSYDSMTLGHGDR---RPYFLNPGEG-------HHTDHP CYTQHNSCQSESST---------YPDLAS--CTFPRRHYSS-----HHELKEECG-ALVPYTGPTGSSKG--DGGGVGSN NRISSTVLEQFDR-QAPVRREGYHTLQYKRT----AVEHQ------------RSDSPGR-------IRHLVHSVQKLF-T KSHSLEGPSGSGGGGSGRVN------------------GCKSSPDDP---PSSSGTLKHTKRSKSKDRSK--------SE PK--------------MRTAIS-------GYWSSDDTLDRDACLYHHH-HGARSGG-----LPSGVMTMGR----HPDKS QSQ-------------------YFM-ESYNTISA--HSLKTSRSNNDV-KCTTCS--VGSGG---SIPLGAG-------- -SMDGQVQ--LKKSSWSSTLTVSRAREVYQK-------------ASVN----------LDKALVKAE-----QGRTCHF- -LQ------------------------------------VPQDD-WSGFSPLG-KDDE--------IPCRRMRSGSYIKA MAE--EDSGDSDG-SPKPSPKV--QARR----------------------ASYLKATQP--------------------- --------------------------SL-----------------TEMTTLNRSLDSLDP------AGLLASPKFR---- ---------SRNESYMRAMSTISQKACFGSKYSKKIVSRDTSLFGFGCKVSEVEVNGQIEA--VCESVFSEMES----QA VDALD--------------------LPVPSCFRMRSHSYVR-AIEKGCSQEE-EEAED-------QSCRPPFTPSTGCIG ----------------------------SAVFLAVSSCITT------YKKTPPPVPPRT----TPSKPFISITAQSSTES AQDAY----MDGGSGPRAGISSQT-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQVHGPPSQHVTNSSITITATATAT------- --ASAVAHISADSKAQREALR-------KCLSIGIQVD--------------------PEEGGPTEEQSKFQSIGIQVED ERCYRR--------MTRSNSVTTAVQADLDDAA--DPPELPPRH-----------------------------F------ ATMPR--QHSRDAATSTVSIQGSGNHYHACTSDDI-------ADVDFDPSILPPPDP-----WMDG-------------- AGEAEAETSEAIGRL----VCPRDGRWFLKLLQAETERMEGWCRRMEQDETEN-------------------ELPDEILG KIR-SAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPVSQDLAGFWDMLQLSIENISLKFDELHQLKA NNWKPLT-----PPEIQ-------E-RRMPPPVPKKPLKG----------------------HPPLAR------------ --------DRSLESSE-----------RQRLEARKRLLAAKRAVS----------------VRQSSATESADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Tetraodon_nigroviridis_DLGAP1_b -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHVIS-YE---PSYDPL-GHHVDR---KPYLISQNDIPVQIPVPHPAELP YYN-AQRTSYPPDS---------NSNIPY--GTFPRRCHSTSS-SHHPEVKDECM-AIVPYDGG-------------KTP TRVSATFADPLER-QSSFSRDGYHTLQYKRGM---LAHSGGMVAN-------NNDSPGR-------IRHLVHSVQKLF-T KSHSLEGPHHTQ-CSKGASN------------------GSRASIEG----ETPPTGPSHRKRSKSRERCRS-------AE PKHRSHHHRHHQLHGSASAPGS-------GYWSSDDNLERELCLYHPHHHQPPPSP--SISPSPIAMTMGR----YTSNI SHQ-------------------YFMMDPYTTLNE--PALKASRSNNDVKYAVSSA----------CVPPLGL-------- -VDGPLMK----KGACSSSLTVSRARELYTNNSSHNQARAGAGSGNLN----------VDRALVKSKG-SQQQERSCHF- -LQVP------------------------------------QDD-WSNFSPLG-KEDD--------IPCRRMRSGSYVKA MAE--DDSGDSDG-SPKPSPKI--QARR----------------------ASYLKATQPSLTEMTTLHIWPY-------- -------------HNKMLSSKS-VYKKP-----------------GTKVEMVKFFPMLPDRFVLKLLCFFCVSLCLF--- ---------SFPCSSVQQLSEVG----------------------------------GKRA--GLSRSTVRCNLRPWGRS MDTMDTMDT----------------LPMPGCFRMRSHSYVR-AIDQGCAGK------GRPLL-LLPSSPPKTSATTVRTI QS------------------------------STVSSCITT------YKKTPPPVPPRTSTCS--SKPYISITAQSSTES AQDAY----MEEE-GPRGDMTLQS-------------------------------------------------------- -------RLSNSTESIDSMKALTAAIEAAN------------------AQVHGPASQHVSSSTMTVSPPKPP-------- VLCRRPVVEDYQDDYRKEAFRK-----GKCLSIGIQVDG-------------------PEEIPDPEDSSKFTSVGVQVED HRGYRR--------CQRSNSVTAAVQADLDIPDLLDTPLDSPVT-----------------------------DMEILPS GVLSR--QYSRDAATSTVSIQGSGNHYHACASDDY-------EDVGFDPSILPPPDP-----WIDS-------------- VTDDPMDVN-VVQRS----VCQRDGRWFLKLLQAETDRMEGWCRQMELDQREN-------------------ALPEDILG KMR-SAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPVASDLAGFWDMLQLSIENISLKYDELHQLRA NNWRPID-----PPERK-------E-RPLPPPVAKKPPKGPH-------------------HHPPLVR------------ --------DRSLESSE-----------KQRQEARKRLMAAKRAAS----------------VRQNSATESADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gasterosteus_aculeatus_DLGAP1_a -------------------------------------------------------------------------------- ----------MKGL-SSSRSH---------HHAVT-CD---PSYDSMTLGHSDR---RSYFLNPGEA-------HPSDHP CYTQRNSFQAECSA---------YPDLAS--CTFPRRHYSS-----HHELKGECG-AVVPYVGPTGCGKG--GGN---NN NRVPPNLLEQFER-QAPVRREGYHTLQYKRT----AVEHQ------------RSDSPGR-------IRHLVHSVQKLF-T KSHSLG------------MN------------------GSKSSPDDP---PSSSGTLKHSKRSKSKDRSK--------SE PK--------------MRGAIS-------GYWSSDDTLDREMCLYHHHRHGGTGGG-----PPTGVMTMGR----HPEKS QSQ-------------------YFM-ESYNTISA--HSLKTSRSNNDV-KCSTCSGSGGGGG---GVPLAG--------- -SQDGQVQ--LKKSSWSSTLTVSRAREVYQK-------------ASVN----------LDKALVKAE-----QGRTCHF- -LQKWETASPTFTFISVCEKSGIHVWEKLQPVYLPSHLQVPQDD-WGSFSPLG-KDDE--------IPCRRMRSGSYIKA MAE--EDSGDSDC-SPKPSPKV--QARR----------------------ASYLKATQPSLTEMTTLEISTE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDSLDP------AGLLASPKFR---- ---------SRNESYMRAMSTIS----------------------------------QIEA--VCESVFSEMES----QA VDALD--------------------LPIPNCFRVRSHSYVR-AIEKGCSQED-EEEAAAAAG-VSRTGSPPRTIQS---- --------------------------------STVSSCITT------YKKTPPPVPPRT----TPSKPFISITAQSSTES AQDAY----MDGGSGPRTGISSQP-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQVHGPASQHVTNSTITITA------------ ---TAVAHVPADSKAQREALR-------KCLSIG--------------------------------IQSKFQSIGIQVED ERC-----------------VTTAVQADLDD---------PAGH-----------------------------C------ ATMPR--QLSRDASSSTVSIQGSGNHYHACAPDDF-------GEAGFDPSILPPPDP-----WMDS-------------- VAEPDSGAPEAVGRS----VCPRDGRWFLKLLRAETERMEGWCRQMEQDEVEN-------------------ELPDEILG KIR-SAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPVSQDLAGFWDMLQLSIENISLKFDELHQLKA NNWKPLT-----PPEIQ-------E-RRMPPPVPKKPPKGH---------------------HPPLAR------------ --------DRSLESSE-----------RQRLEARKRLLAAKRAAS----------------VRQSSATESADSIEIYIP- ---------------------------------------------EAQTR------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gasterosteus_aculeatus_DLGAP1_b -------------------------------------------------------------------------------- ----------MKGL-SGSRSH---------HHVVS-YE---PSYDLL-GHHVDR---KPYLISQNDMPVPIPMPHQAELS YYN-AQRTPYPSES---------NSIVPY--GTFPRRCHSTSS-SHHPEVKDECM-AMVPYYGG-------------KTP TRVP----EPFER-QPSFPRDGYHTLQYKRGV---LAHSGGVGAQH-----NNNDSPGR-------IRHLVHSVQKLF-T KSHSLEGPHHPQ-NSKGANN------------------GSGANPEG----EIPPVGVRQRKRSKSRERCRS-------AE PKHRSHHHPHHQLHGSASAPGS-------GYWSSDDNLERELSLYHPHHHQPPPSPSPSISPSPIAMTMGR----YPGNS QSQQYFMMDPYGTLNEHTHTHAHTHAHHGHTHHH--SALKVSRSNNDVKYAASSA----------CVPSLGL-------- -VDGPLVK----KGAWSSSLTVSRAREVYTNNSSHNQPRASAGASNLN----------LDRALVKSKG-SQLQERSCHF- -LQVWG--AIFLYLEWAIAPSVHIWYRTDCEICTLLSRQVPQDE-WSGFSPLG-KEDD--------IPCRRMRSGSYVKA MAE--EDSGDSDG-SPKPSPKM--QARR----------------------ASYLKATQPSLTEMTTLQISSE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDTLDPKTLLDPKSLLSSPQYR---- ---------SRNESYMRAMSTIS----------------------------------QIEQ--VCEQVYSAMQAQAMEAA IDSMETMDT----------------LPMPGCFRMRSHSYVR-AIDQGCSGDE-EGEGGRPLL-LLPSSPPRTSATTVRTI QS------------------------------STVSSCITT------YKKTPPPVPPRTSTCSTASKPYISITAQSSTES AQDAY----MEEE-GPRGDMTIQS-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQVHGPASQHVSNSAMTVCTPTPS-------- VHSRGAVIEDHRDVYRKEALRK-----GKCLSIGIQS--------------------------------KFTSIGVQVED DRG-----------------VTTAVQADMDIPDAMDTPLDSPDT-----------------------------DMEVLSS GALSR--QYSRDAATSTVSIQGSGNHYHACASDDY-------DDVGFDPSILPPPDP-----WIDS-------------- VTDDSLDV---VQRS----VCHRDGRWFLKLLQAETDRMEGWCRQMELDQQDN-------------------DLPDDVLG KMR-SAVGSAQLLMSQKFQQFRELCEENLNPNAH----------P--RPVASDLAGFWDMLQLSIENISLKFDELHQIRA NNWRPLD-----PPERK-------E-RRLPPPVPKKPPKAPH-------------------HHPPLAR------------ --------DRSLESSE-----------KQRQEARRRLMAAKRAAS----------------VRQNSATESADSIEIYIP- ---------------------------------------------EAQTR------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Oryzias_latipes_DLGAP1_b -------------------------------------------------------------------------------- ----------MKGL-SGSKSH---------HHVVS-YE---PSYDPL-GHHVDR---KQLLISQMDIPVPVPMP--AEHP YYN-AQRTSYPSDS---------NSIVPY--GTFPRRCHSTSS-SHHPEVKDECM-AIVPYDGG-------------KMQ TQVPVNIVDQYEH-QPPFSRDGYHTLQYKRGV---LAHTGGMGTND-----NNNDSPGR-------IRHLVHSVQKLF-T KSHSLEGPHHTQ-SSKGAHNG-------SVNGGGGGGGGSRASPEG----GNPSAGVRHRKRSKSRERCRS-------AE PKHRSYHHHHPQLHGSASAPGS-------GYWSSDDNLERELCLYHPHHHQPPPSPSPSISPSPIAMTMGR----CVDNN PDK--------------------FHARHGHTHHH--SALKASRSNNDLKYAASSA----------CLPPVGL-------- -LDGPLVK----KGAWSSSLTVSRAREVYTN-SSHNQPRASAGSGNLN----------LDRALVKSKG-SQQQDPSCHF- -LQIW---YYQSVQTAVYLPGLFVAWAKSGSYANLNNFQVPQDE-WSGFSPLG-KEED--------IPCRRMRSGSYVKA MAE--DDSGDSEG-SPKPSPKV--QARR----------------------ASYLKATQPSLTEMTTLQISTE-------- -------------HSPKLQIRSHSYLRA-----------------VSEVSINRSLDTLDPKSLLDPKSLLSSPQYR---- ---------SRNESYMRAMSTIS----------------------------------QIEQ--VCEQVYSEMQSQAMEAA MDSLETMDT----------------LPMPGCFRMRSHSYVR-AIDQGCAGEE-EGEGGRPLL-LLPSSPPRTSATTVRTI QS------------------------------STVSSCITT------YKKTPPPVPPRTSTCSTASKPYISITAQSSTES AQDAY----MEEE-GPRGDMTIQS-------------------------------------------------------- -------GLSNSTESIDSMKALTAAIEAAN------------------AQVHGPASQHVNNSTMTVSVPNSS-------- ALSRGYSIEDHRDEYRKEALRK-----GKCLSIGIQS--------------------------------KFTSVGVQVED DRG-----------------VTTAVQADLDLPDMLDMPMDSPEP-----------------------------NRHILSP NALSR--QYSRDAATSTVSIQGSGNHYHACASDEY-------DDVGFDPSILPPPDP-----WIDN-------------- VTDDPLCV---ASRS----ICQRDGRWFLKLLQAETDRMEGWCQQMELDQQEN-------------------DLPDEVLG KMR-SAMESAQHLMSQKFQQFRELCEENLNPNIH----------P--RPVASDLAGFWDMLQLSIENISLKFDELHQLRA NNWRPLD-----PPERK-------E-RRLPPPVPRKPHKGPH-------------------QHPPLVR------------ --------DRSLESSE-----------KQRQEARKRLMAAKRAAS----------------VRQNSATESADSIEIYIP- ---------------------------------------------EAQTR------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Amphimedon_queenslandica_DLGAP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------MS QARETQYKYKGRSKGVESRLKGKALDSKRQR------------------------------------EELLSGRRR---- -------------AALLEINE-----------------------------------EIMAEEEIQEKGTGAT-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------GKKKTSDDRKEELLK--------------------------WKKERDRKKQKEQKKANAKPAF- -------------------------------------------------------------------VVGKANISSNRKV PLPVEPSSTATVKEGPSKKGGKRVTEPPG--------------------------------------------------- --------------NAKREELGRKRVTGSR--------------QPDKVQKPATRSSVRL-------------------- --------------------------------------------------------QTAKSKETKAVKQSTKKQLTAESS KSTNS----------------------KREITKELSPHPPPCIDKSDLQRDSVLSSAWIP------GAPPTPQCASQNAR PNFEQ----------------------------------FFSKQVFSPFQFKGQTGG-----ETNTGKAQSIFTFRKEFR EEDIIKR-------IEDDSISNIEE------------------------------------------------------- --------EKREEKEAAVPATDDTGRGKSAK------------------KEVKGGGRKRNLKKRQNE------------- -------------RTEKESDDE-------------------------------EDLETIDTGTKIGREEEPVDELPTNVR MSDTS--------------------IEAINVSVAHNNNYTNQQLEEER-------------------------------- -------QSSTDPPASAHTQDLSPPVTNFAPPTTDVTPPS---------------------------------------- ---------EGLATDATGNDSGFDLVPFYKRHTDVTQRFNALCAEWDDKLSQLEDDGEKEED---------AGRPSDEVI GDIRTTVCQAKLLMRQKLKQYLELVQQAED------------PAAEHKTMAEDLQGFWDMVYFQVESIYKKFSSFSEMES NSWKTVVTPAEDGDSTTCKPRRS--KRGASKAKRGGSKTGAS-------------------SAISERLK----------- --------AARAKREAER--------LKIREMRQAFAAASKTKE--------------EEEVPPAPVTPEKKDNIAESP- --------------------------------------------FPDLISFSP--------------------------- ----------------------------------------------------------------------------APSS LRPPTTPKSLLKTPQSASKSKSSLKKRLSSIPDPVFEVDKSHET------------------------------------ --------EGAFMTKLVQINASKKMIKDFDTNLIMSPARRSKRLSTRRRSELIVSSISEIPNDRNNVAYLPNEALID--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Homo_sapiens_DLGAP2 -------------------------------------------------------------------------------- ----------MKGL-SGSRTQ----PPLCSGHTCGLAPPEDCEH----LHHGPDAR-PPYLLSPADSCPGG------RHR -CSPRSSVHSECVMMP------VVLGDHVSSSTFPRMHYSSH-----YDTRDDCAVAHAGA-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---AAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNANGTKADGR-------ADD-------HHHAHHA------------KHSKRSKSKERKP---------E GK--------------PRPGMS-------SWWSSDDNLDSDSTYRTPS-------------------VLNR----HHLGP VAH--------------------CYPDALQSPFG-DLSLKTSKSNNDVKCSACEG-------------LALT-------- -PDAKYLK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLLHQDAKP--ALRPCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---SAILP---------------------EPLLKSIGQRPLG----------------- ------------EHQTQTYLQAASDVP-------------------VGHSLDPAANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQVS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------MMTPSDITSTIRST A----------------------------------AVSYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYQD-----SRAQRMSPWPQD-------------------------------------------------------- -SRG----LYNSTDSLDSNKAMNLALETAAA------------------QRHLPESQSSSVRTS---------------- -------DKAILVSKAEELLKS-----RCSS-IGIQDSEFP-EHQP---YPRSDVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHITTEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYSAVRTVRTQGLFSYRED-------YRTQVDTSTLPPPDP-----WLEP-------------- -AIDTVETG-RMSP------CRRDGSWFLKLLHAETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRL NDWKMME-----SPERK-------EERKVPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSASERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Pan_troglodytes_DLGAP2 -------------------------------------------------------------------------------- ----------MKGL-SGSRTQ----PPLCSGHTCGLAPPEDCEH----LHHGPDAR-PPYLLSPADSCPGG------RHR -CSPRSSVHSECVMMP------VVLGDHVSSSTFPRMHYSSH-----YDTRDDCAVAHAGA-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---AAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLESSSKSNANGTKADGR-------ADD-------HHHAHHA------------KHSKRSKSKERKP---------E GK--------------PRPGMS-------SWWSSDDNLDSDSTYRTPS-------------------LLNR----HHLGP VAH--------------------CYPDALQSPFG-DLSLKTSKSNNDVKCSACEG-------------LALT-------- -PDAKYLK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLLHQDAKP--ALRPCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---SAILP---------------------EPLLKSIGQRPLG----------------- ------------EHQTQTYLQAASDVP-------------------VGHSLDPAANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQVS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------MMTPSDITSTIRST A----------------------------------AVSYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYQD-----SRAQRMSPWPQD-------------------------------------------------------- -SRG----LYNSTDSLDSNKAMNLALETAAA------------------QRHLPESQSSSVRTS---------------- -------DKAILVSKAEELLKS-----RCSS-IGIQVAALG-RPR----RSLLNVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHITMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYSAVRTVRTQGLFSYRED-------YRTPVDTSTLPPPDP-----WLEP-------------- -AIDTVETG-RMSP------CRRDGSWFLKLLHAETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRL NDWKMME-----SPERK-------EERKVPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gorilla_gorilla_DLGAP2 --------------------------------------------------------------------PQYSWSPTQHFN EERYSPAPRSMKGL-SGSRTQ----PPLCSGHTCGLAPPEDCEH----LHHGPDAR-PPYLLSPADSCPGG------RHR -CSPRSSVHSECVMMP------VVLGDHVSSSTFPRMHYSSH-----YDTRDDCAVAHAGA-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---AAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNANGTKADGR-------ADD-------HHHAHHA------------KHSKRSKSKERKP---------E GK--------------PRPGMS-------SWWSSDDNLDSDSTYRTPS-------------------VLNR----HHLGP VAH--------------------CYPDALQSPFG-DLSLKTSKSNNDVKCSACEG-------------LALT-------- -PDAKYLK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLLHQDAKP--ALRPCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---SAILP---------------------EPLLKSIGQRPLG----------------- ------------EHQTQTYLQAASDVP-------------------VGHSLDPAANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQVS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------MMTPSDITSTIRST A----------------------------------AVSYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYQD-----SRAQRMSPWPQD-------------------------------------------------------- -SRG----LYNSTDSLDSNKAMNLALETAAA------------------QRHLPESQSSSVRTS---------------- -------DKAILVSKAEELLKS-----RCSS-IGIQDSEFP-EHQP---YPRSDVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHITMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYSAVRTVRTQGLFSYRED-------YRTQVDTSTLPPPDP-----WLEP-------------- -AIDTVETG-RMSP------CRRDGSWFLKLLHAETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRL NDWKMME-----SPERK-------EERKVPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Mus_musculus_DLGAP2 MGTAQVLPGILQKHCCILPDRNTESQCT-----------LCGEPEEEEGGDLAQPGLSFPGPAEEDIDQQYSWSPTQHFN EERYSPAPRNMKGL-TGSRNQ----PQLCAGHTCGLSPPDDCEHPHDHMHHGSDVR-QPYLLSPAESCPMD------HHR -CSPRSSVHSECMMMP------VMLGDHVSSSTFPRMHYSSH-----YDTRDDCAMSHTST-----------------KV NRIPANLLDQFEK-QLPLHRDGFHTLQYQRAS---AATE------------QRNESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNINGTKSDSR-------VDD-------HHQSHLS------------KHSKRSKSKERKP---------E SK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VAHR----HHMDH IPH--------------------CYPEALQSPFG-DLSLKTSKSNNDVKCSACEG-------------LALT-------- -PDTRYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLVHPEIKP--SLRPCHY- -LQ------------------------------------VPQDD-WGAYPTGGKEEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPT---VAIRP---------------------EPLLKPIIQRPLG----------------- ------------DHQTQSYLQAATEVP-------------------VGHSLNPSINYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEVNGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------VMTSSNMTSTIRST A----------------------------------AVSYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYQD-----SRAQRMSPWPQD-------------------------------------------------------- -SRGG---LYNSMDSLDSNKAMNLALETAAA------------------QRHAADTQSSSTRSI---------------- -------DKAVLASKAEELLKS-----RCSS-IGVQDSEFP-DHQP---YPRSDVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHVSMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYGALRTVRTQGLFSYRED-------YRTQVDTSTLPPPDP-----WLEP-------------- -SLDTVETG-RMSP------CRRDGSWFLKLLHTETKRMEGWCKEMEREAEEN-------------------DLLEDILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSVEDVSMKFDELHQLKL NDWKIIE-----SPERK-------EERKIPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Rattus_norvegicus_DLGAP2 -------------------------------------------------------------------DQQYSWSPTQHFN EERYSPAPRNMKGL-TGSRNQ----PQLCVGHTCGLSPADECEHPHDHVRHGPDVR-QPYLLSPAESCPMD------HHR -CSPRSSVHSECMMMP------VMLGDHVSSSTFPRMHYSSH-----YDTRDDCATSHAST-----------------KV NRIPANLLDQFEK-QLPLHRDGFHTLQYQRAS---AATE------------QRNESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNINGTKSEGR-------MDD-------HHQSHLS------------KHSKRSKSKERKP---------E SK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VAHR----HHMDH IPH--------------------CYPEALQSPFG-DLSLKTSKSNSDVKCSACEG-------------LALT-------- -PDTRYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLVHPEIKP--SLQPCHY- -LQ------------------------------------VPQDD-WGAYPTGGKEEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPT---VALRP---------------------EPLLKSIIQRPLG----------------- ------------DHQTQSYLQAATEVP-------------------VGHSLDPSVNYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEVNGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------VMTPSNMTSTIRST A----------------------------------AVSYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYQD-----SRAQRMSPWPQD-------------------------------------------------------- -SRGG---LYNSMDSLDSNKAMNLALESAAA------------------QRHAADTQSSSTRSI---------------- -------DKAVLVSKAEELLKS-----RCSS-IGVQDSEFP-DHQP---YPRSDVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHVSMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYGALRTVRTQGLFSYRED-------YRTQVDTSTLPPPDP-----WLEP-------------- -SLDTVETG-RMSP------CRRDGSWFLKLLHTETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSVEDVSMKFDELHQLKL NDWKIME-----SPERK-------EERKIPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Loxodonta_africana_DLGAP2 ---------------------------------------------EEEGGDLAQPGISFPGPAEEELDQRYSWSPTQHFN EERYSPAPRNMKGL-SGSRNQ----PQLCSGHTCGLTPPEDCEHTHDHIHHGQETR-QSYLLSPTDSCPMD------HHR -CSPRSSIHSECMMMP------VMMGDHMSSSTFPRMHYSSH-----YDTRDDCAMSHAST-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---TAE-------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNVNGTKGDSR-------VDD-------HHHGHHS------------KHSKRSKSKERKP---------E SK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VINR----HHVDH ISH--------------------CYPETLQGPFG-DLSLKTSKSNNDVKCSACEG-------------LSMT-------- -PDTKYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLVHQEIKP--SLRPCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---VAIRP---------------------EPLLKSIGQRPLG----------------- ------------DHQTQSYLQAASDVP-------------------GGHNLDPSANYTSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------AMTSSDIASTIRST A----------------------------------AISYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYHD-----SRTQRISPWPQD-------------------------------------------------------- -GRG----LYNSTDSLDSNKAMNLALESAAA------------------QRQASESQGGSARTS---------------- -------DKAILVSKAEEFLKS-----RRSS-IGIQDSEFP-EHQP---YPRSDVETAADSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAGVQADLELEGFPGHITMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYGAVRTVRTQGLFSYRED-------YRTQVDTSNLPPPDP-----WLEP-------------- -SIETVETG-RMSP------CRRDGSWFLKLLHTETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSIEDVSMKFDELHHLKL NDWKIIE-----SPERK-------EERKVPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Dasypus_novemcinctus_DLGAP2 -------------------------------------------------------------------DQQYSWSPTQHFN EERYSPAPRNMKGL-SGSRNQ----PQLCSGHTCGLTPPEDCEHSHDHLHHGQETR-QSYLLSPTDSCPMD------HHR -CSPRSSIHSECMMMP------MMMGDHMSSSTFPRMHYSSH-----YDTRDDCAMSHAST-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---TAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNVNGTKGDSR-------MDD-------HHHGHHS------------KHSKRSKSKERKP---------E SK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VLNR----HHVDH ISH--------------------CYPETLQSPFG-DLSLKTSKSNNDVKCSACEG-------------LAMT-------- -PDTKYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLIHQEIKP--SLRSCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---VATRP---------------------EPLLKSIAQRPLG----------------- ------------DHQTQSYLQAASDVP-------------------GGLGLDPSANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------AMTSSNITSTIRST A----------------------------------AAPYTN------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYHD-----SRAQRGSPWPQD-------------------------------------------------------- -ARG----LYNSTESLDSNKALNLALETAAA------------------QRHAAEGQGGSARAG---------------- -------DKAVLGAKAEEFLRS-----RRAS-VGIQDSEFP-EHQP---YPRSDVETATDSDTESRGLREYHSVGVQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHVTTEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYGAVRTVRTQGLFSYRED-------YRTQVDTPNLPPPDP-----WLEP-------------- -SIETVETG-RMSP------CRRDGSWFLKLLHTETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNMDPSAM----------P--RPTSQDLAGYWDMLQLSIEDVSMKFDELHQLKL NDWKMIE-----SPERK-------EERKVPPPIPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Monodelphis_domestica_DLGAP2 -------------------------------------------------------------------DQQYSWSPTQHFN EERYSPAPRNMKGL-SSSRNQ----PQLCSGHTCGLTPPEDCEHTHDHLHHGQEPR-QSYLLSPTESCPMD------HHR -CSPRSSIHSECMMMP------MMMGDHMSSSTFPRMHYSSH-----YDTRDDCAMSHAST-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---NAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKSNVNGTKSDSR-------GDD-------HHHGHPS------------KHSKRSKSKERKP---------E SK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VVNR----HHVDH ISH--------------------CYPDALQSHFG-DLSLKTSKSNNDMKCSACEG-------------LAMT-------- -PDGKYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLVHQEIKP--ALRPCHY- -LQ------------------------------------VPQDE-WGGYPTGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGESDS-SPKTSPK---VAVRT---------------------EALLKSIGQRPLG----------------- ------------DHQTQSYLQAAGDVP-------------------GGHNLDPTANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEINGQFES--VCESVFSEVES----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------AMTSSNITSTIRST T----------------------------------AVSYTS------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYHD-----SRTQRIPPWPQD-------------------------------------------------------- -GRG----LYNSTDSLDSNKAMNLALETAAA------------------QRHASESQSSSVRTS---------------- -------DKAVLVTKAEEFLKS-----RRSS-IGIQTEMFPTHSLP---YHSSTVETATDSDTESRGLREYHSVGIQVED DKR-HGR-------FKRSNSVTAAVQADLELEGFPGHITMEDKG-----------------------------LQFGSSF QRH------SEPSTPTQYGAVRTVRTQGLFSYRED-------YRTPVDTSNLPPPDP-----WLEP-------------- -SIETVETG-RMSP------CRRDGTWFMKLLHTETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNLDPSAM----------P--RPTSQDLAGFWDLLQLSIEDVSMKFDELHQLKL NEWKLIE-----SPERK-------EERKVPPPVPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------- >Gallus_gallus_DLGAP2 MGTIQVLPGILQKHCCILPDRNTESQCTLCGEPEDLDSLTGHAFPEDEGGDLLKSSFSFPGTPEEEIDQQYSWSPSHHFN EERYSPASRNMKGL-SGSRNQ----PQLCSAHTCGLASPEDCEHTHDHIHHGQEPR-QSYLLSPTESCPMD------HHR -CSPRSSIHSECMMMP------MVMGDHMSSSTFPRMHYSSH-----YDTRDDCAMSHGNP-----------------KI NRIPANLLDQFEK-QLPLHRDGFHTLQYQRTS---TAAE------------QRSESPGR-------IRHLVHSVQKLF-T KSHSLEGSSKGNVNGTKGDSR-------GDD-------HHHGHHS------------KHGKRSKSKERKP---------E TK--------------HKSGMS-------SWWSSDDNLDSDSTYRTPS-------------------VVNR----HHADH ISH--------------------CYPEALQGHFG-DLSLKTSKSNNDVKCSACEG-------------LAMT-------- -PDSKYMK----RSSWS-TLTVSQAKEAYRK-------------SSLN----------LDKPLVHQEIKP--SLRPCHY- -LQ------------------------------------VPQDE-WGGYPAGGKDEE---------IPCRRMRSGSYIKA MGDE--ESGDSDT-SPKTSPK---LAVRP---------------------ESLLKSIGQRPLG----------------- ------------DHQNQSYLQTASDVP-------------------GGHNLDPSANYNSP-------------KFR---- ---------SRNQSYMRAVSTLSQASCVSQMS-------------------EAEVNGQFES--VCESVFSEVEA----QA MDALD----------------------LPGCFRTRSHSYLR-AIQAGYSQDD-ECIP---------AMASSNITSTIRST T----------------------------------AVTYTS------YKKTPPPVPPRT-----TSKPLISVTAQSSTES TQDAYHD-----SRAQRMSPWPQD-------------------------------------------------------- -GRG----MYNSTDSLDSNKAMNLALETAAA------------------QRHVSES--ASIRTS---------------- -------DKAILVTKAEEFLKS-----RRSS-IGIQ------------------VETATDSDTESRGLREYHSVGIQVED EKR-HGR-------FKRSNSVTAAVQADLELEGFPGHITMEDKG-----------------------------LQFGSSF QQH------SEPSTPTQYSAVRTVRTQGLFSYRED-------YRTPVDTSNLPPPEP-----WLEP-------------- -AIETVETG-RMSP------CRRDGSWFMKLLHTETKRMEGWCKEMEREAEEN-------------------DLSEEILG KIR-SAVGSAQLLMSQKFQQFYWLCQQNLDPSAM----------P--RPTSQDLAGFWDLLQLSIEDVSMKFDELHQLKL NEWKIIE-----SPERKPTGWWM-EERKVPPPVPKKPPKG----------------------KFPITR------------ --------EKSLDLPD-----------RQRQEARRRLMAAKRAAS----------------FRQNSATERADSIEIYIP- ---------------------------------------------EAQTRL----------------------------- 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