>Homo_sapiens_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNATT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKVAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIR------TGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKK------LQQYPRLREEMERIVTTHI REREGRTKEQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSNQMN---KKKTSGNQ-------DEILVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPS-------------------------------RSGQASP---SRPESPRPPFDL--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Pan_troglodytes_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNATT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKVAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIR------TGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKK------LQQYPRLREEMERIVTTHI REREGRTKEQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSNQMN---KKKTSGNQ-------DEILVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVP-----------------------------------RITI---SDP------------------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Macaca_mulatta_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNATT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKVAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIRHTQ---TGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKK------LQQYPRLREEMERIVTTHI REREGRTKEQVMLLIDIELAYMNTNHEDFIGFAK---------AQ-RSNQMN---KKKTSGNQ-------VSLPVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDSFMHSMDPQLERQVETIR-SGDRYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSC GDQNTLMEESAEHAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPS-------------------------------RSGQASP---SRPESPRPPFDL--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Mus_musculus_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNSTT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKIAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIR------TGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKK------LQQYPRLREEMERIVTTHI REREGRTKEQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSNQMN---KKKTSGNQ-------DEILVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPS-------------------------------RSGQASP---SRPESPRPPFDL--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Canis_familiaris_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNATT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGTNKGISP-VPINLRVYSP--QVLNLTWKDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKVAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ISAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNRLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIR------TGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKK------LQQYPRLREEMERIVTTHI REREGRTKEQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSNQMN---KKKASGNQ-------DEILVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPS-------------------------------RSGQASP---SRPESPRPPFDL--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Monodelphis_domestica_DNM1 ---------------------------------------------------------------------PVPERGAPGGG AQAAAAAAMGNRGMEDLIPLVNRLQDAFSAIGQ-NANLDLPQIAVVGGQSAG-SSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNATT-------------------------------------EYAEFLHCKG--------KKFTDFEEVRLEI EAETDRVTGSNKGISA-VPINLRVYSP--HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKIAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALAAERKFFLSHPSYRHLAERMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPS RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIRHVGGHGTGLFTPDLAFEAIVKKQVQKLKEPTLKCVDMVVSELTATIRKCSAK------LQQYPHLREEMERIVTTHI REREGKTKDQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSSQMN---KKKAAGNQ-------DEILVIRKSW LTINNIGIMK-------------------GGSKEYWFVLTAENLSWYKDDEEKEKKYMLPVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKEK------------------ ----ASETE-ENG--SDNFMHSMDPQLERQVETIRNLVDSYMAIVNKTIRDLMPKTIMHLMINNTKDFIHSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALGIIGDINTTTISTPMPPPVDDS----WLQVQSVPAG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPA----------GSALGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVP--------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Anolis_carolinensis_DNM1 -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSAIGQ-NANLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVNANT-------------------------------------EYGEFLHCKG--------KKFTEFDEIRQEI EAETDRVTGSNKGISA-VPINLRVYSP--NVLSLTLVDLPGMTKVPVGDQPSDIEFQIRDMLMQFVTKENCLILAVSPAN SDLANSDALKIAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YVGVVN--RSQKDIDGKKD IQAALAAERKFFLTHPAYRHMADRMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GIR------TGLFTPDLAFEAIVKKQVQKLKEPCLKCVDMVVSELTSTIRKCSNK------LSQYPHLREEMERIVTTHI RDREGKTKDQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSSQMS---KKKTAGNQ-------DEILVIRRNW LDRSRIGLSRK------------------GGGRPNWWRLSIEELVWLKDPLEKEKKYMLPVDN-LKVRDIEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVV---------------------- ----SGDSE-ENG--SDSLMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKDFIHSELLANLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALNIIGDINTTTISTPLPPPVDDS----WLQYR--------SPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPAG---------GPTLGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPSPPWP--------------------------SKKGPASP---TRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Pelodiscus_sinensis_DNM1 -------------------------------------------------------------------------------- -------------MEDLIPLVNRLQDAFAAIGQ-NADLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTSTT-------------------------------------EYGEFLHCKG--------KKFTDFEEIRLEI EAETDRVTGSNKGISP-VPINLRVYSP--NVLSLTLVDLPGMTKVPVGDQPLDIEFQIREMLMQFVTKENCLILAVSPAN SDLANSDALKIAKEVDPQ-G-----QRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD IQAALAAERKFFLSHPAYRHMAERMGTPYLQKVLNQQ----LTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPA RKTKALLQMVQQFA--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVQ--MEFDEKELRREISYAIKNIH GIR------TGLFTPDLAFEAIVKKQVQKLKEPSLKCVDMVVSELTSTIRKCSEK------LSQYPHLREEMERIVTTHI REREGRTKDQVMLLIDIELAYMNTNHEDFIGFAN---------AQQRSSQMS---KKKAAGNQ-------DEILVIRKGW LTINNIGIMK-------------------GGAKEYWFVLTAENLSWYKDDEEKEKKYMLPVDN-LKLRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACETQEEVD----SWKASFLRAGVYPERVGDKDK------------------ ----TSESE-ENG--SDSFMHSMDPQLERQVETIRNLVDSYMGIVNKTIRDLMPKTIMHLMINNTKDFIHSELLANLYSC GDQNTLMEESSEQAQRRDEMLRMYHALKEALNITGDINTTTISTPMPPPVDDS----WLQVQNIPSG-RRSPTSSPTPQR ----RAPAVPP-ARPG------SRGPAPGPPPAG---------GPTLGGAPPVPSRPGASP-------DPF-----GPPP QV--PSRPNRAPP-GVPS-------------------------------RPGKASP---SRPESPKPPFEM--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Danio_rerio_DNM1_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRMQDAFSAIGQ-NANLDLPQIAVVGGQSAGKSSVLENFV-GKDFLPR--GSGIVT--R RPLVLQLINCPT-------------------------------------EYAEFLHCKG--------KKFTDFDEVRQEI EAETDRVTGQNKGISP-VPINLRVYSP--NVLNLTLVDLPGMTKVPVGDQPADIEHQIKDMLMQFVTKENCLLLAVSPAN SDLANSDALKIAKEVDPQ-G-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD INAAMAAERKFFLSHPSYRHLADRMGTPYLQKTLNQQ----LTNHIRDTLPGLRAKLQSQLLSIEKEVEEYKNFRPDDPS RKTKALLQMVQQFS--VDFEKRIEGSG---DQIDTYELSGGARINRIFHERFPFELVK--MEFDEKELRKEISYAIKNIH GIR------TGLFTPDMAFETIVKRQIGKIKEPCQKCVDMVISELVNTVRQCTKK------LAQYPMLREEMERIVTQHI RDRESRTKNQVLLLIDIELAYMNTNHEDFIGFAN---------AQQRSSQI----KKKAAGNQ-------DEIMVIRKGW LTINNIGIMK-------------------GGAKEYWFVLTAESLSWYKDDEEKEKKYMLQVDN-LKFRDVEKGFMSS--- ----KHIFALFNTEQR-NVYKDYRQLELACESQEEVD----GWKASFLRAGVYPERVVEKE------------------- ----KNDAGEENG--SDGFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLIPKTIMHLMINNTKEYINAELLASLYSC GDQNTLMEESAEQAQRRDEMLRMYHALKEALNIIGDISTTTISTSLPPPVDDS----WLQVQRTGSG-GRSPATSPTPQR ----RAPPPGPPARPG------SRGSAPGPPAA---------------GGPPVPSRPGASP-------DPF-----GGPP PT-VPSRPNRAPP-SVPSR-------------------------------RP------------PASPTRPY-------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Tetraodon_nigroviridis_DNM1_a -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNRLQDAFASIGV-ISSLDLPQIAVVGGQSAGKSSVLENFV-GKDFLPR--GSGIVT--R RPLVLQLINCPT-------------------------------------EYGEFLHCKG--------KKFTDFEEVRQEI EAETDRVTGQNKGISP-VPINLRVHSP--HVLNLTLVDLPGMTKVPVGDQPPDIEHQIRDMIMQFVTKDNCLLLAVSPAN SDLANSDALKIAKEVDPQ-G-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALQAERKFFLSHPSYRHLADRMGTAYLQKVLNQQ----LTNHIRDTLPGLRSKLQSQLLSIEKEVEEYKNFRPDDPG RKTKALLQMVQQFA--VDFEKCIEGSG---DQVDTYELSGGAKINRIFHERFPFELVK--LESDEKTLRKEISYAIKNIH GIR------TGLFTPDMAFETIVKRLIAQIKEPCQKCVDMVIGELVNTVRQCTQK------LAHYPLLREEMERIVTQHI RDRESRTKDQVMLLIDIELAYINTNHDDFIGFAN---------AQQKSSQI----KKKTTGNQ-------DEIMVIRKGW LTINNIGIMK-------------------GGAKEYWFVLTAETLCWYKDDEEKEKKYMLPVDN-LKLKDIEKSFMSS--- ----KHVFALFNTEHRWNVYKDYRQLELASESQEEVD----SWKASFLRAGVYPERSVDKEK------------------ ----VEVAEEATG---DGHIHSLDPQLERQVEIVRNLVDSYLSIIHRTVRDLIPKTIMHLMVNNAKDFIHSDLLAHLYSC GDQNSLMEESQEQAQHRDEMLKMYHALREGLSIIGDISTSTITTAMPPPVDDS----WLQVTGMPSG-RRSPMSSPTPQR ----RA-PPG----------------PPRPGGR------------------GPPSRPAVSP-------EP-------GPP PS-VPSRPNRAPPPGVPRV-------------------------------PVG-----------SALFLPS--------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Oryzias_latipes_DNM1_a ---------------------------------------------------------------------PCSREEAVTGR DRRAAAAAMGNRGMEELIPLVNRLQDAFSAIGQ-NASLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTCPT------------------------------------AEYAEFLHCKG--------KKFTDFDEVRQEI EAETDRITGHNKGISP-VPINLRVYSPNAAVLNLTLVDLPGMTKVPVGDQPPDIEQQIKDMLLQFVTKDNCLLLAVSPAN SDLANSDALKIAKEVDPQ-G-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD ITAALQAERKFFLSHPAYRHLADRMGTAYLQKILNQQ----LTNHIRDTLPGLRSKLQSQLLSIEKEVEEYKNFRPDDPS RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTYELSGGAKINRIFHERFPFEMVK--LESDEKTLRKEISYAIKNIH GIR------TGLFTPDMAFETIVKRQIGQIKEPCQKCVDMVIGELVNTVRQCTQK------LAQYPMLREEMERIVTQHI RDRESRTKDQVLLLIDIELAYVNTNHEDFIGFAN---------AQQKSSQLS---KKKAAGNQ-------DEIMVIRKGW LTINNIGIMK-------------------GGAKEYWFVLTAETLSWYKDDEEKEKKYMLPVDN-LKLKDIEKSFMSS--- ----KHIFALFSTEHR-NVYKDYRQLELASESQEEVD----SWKASFLRAGVYPERSVDKEK------------------ -----AEAEDSNS---DSQIHSLDPQLERQVEIVRNLVDSYLSIIHRTVRDLIPKTIMHLMVNNTKEFIHADLLAHLYSC GDQNTLMEESQEQAQRRDEMLRMYHALREGLNIIGDISTTTVTTTAPPPVDDS----WLQVTGMPCG-RRSPMSSPTPQR ----RA-PPG----------------PPRPGGR---------------AAPGPPSRPAVSP-------DP-------GPT PS-VPSRPNRAPPPGVPRI-------------------------------SVSDQ------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Homo_sapiens_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EHAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LSSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQGE-------ILVIRRGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEDG---AQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WLQSASS-----HSPTPQRRP-- ----VSSIHPPGRPPA------VRGPTPGPPLIPVPVG-----AAASFSAPPIPSRPGP-QS--VFANSDL-----FPAP P-QIPSRPVRIPP-GIPPGVP---------------------------RRPPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Macaca_mulatta_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LSSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPN-----------QVIRRGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEDG---AQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WLQSASS-----HSPTPQRRP-- ----VSSIHPPGRPPA------VRGPTPGPPLIPVPVG-----AAASFSAPPIPSRPGP-QS--VFANNDL-----FPAP P-QIPSRPVRIPP-GIPPGVPS--------------------------RRPPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Mus_musculus_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPTLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELISTVRQCTSK------LSSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQGE-------ILVIRRGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEDG---AQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQSSLMEESAEQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WLQNTSG-----HSPTPQRRP-- ----VSSVHPPGRPPA------VRGPTPGPPLIPMPVG-----ATSSFSAPPIPSRPGP-QS--VFANNDP-----FSAP P-QIPSRPARIPP-GIPPGVP--------------------------SRRAPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Canis_familiaris_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LNSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQGE-------ILVIRRGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEDG---VQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WLQSTTS-----HSPTPQRRP-- ----LSSVHPPGRPPA------VRGPTPGPPLIPVPVG-----PTASFAAPPIPSRPGP-QS--MFANNDP-----FSAP P-QIPSRPARIPP-SIPPGVP--------------------------SRRPPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Felis_catus_DNM2 -------------------------------------------------------------------------------- -----------------------------------------QIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRTALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LSSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQPP-------PQVIRRGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEDG---VQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WIQSSSS-----HSPTPQRRP-- ----ISSVHPPGRPPA------VRGPTPGPPLIPMPA--------ASFAAPPIPSRPGP-QS--VFANNDP-----FSAP P-QIPSRPARIPP-GIPPGVP--------------------------SRRPPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Myotis_lucifugus_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGTNKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKMAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQ----LTNHIRESLPTLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LSSYPRLREETERIVTTYI REREGRTKDQILLLIDIEQSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQGE-------ILVIRKGW LTINNISLMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACESQEEVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEEGG--VQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSS ADQTSLMEESAEQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDT----WLQSTSN-----HSPIPQRRP-- ----VSSVHPPGRPPA------VRGPTPGPPLMPVPVG-----PAASFSAPPIPSRPIP-QS--VFANNDP-----FMAP P-QIPSRPARIPP-GIPPGVP--------------------------SRRPPAAP----SRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Anolis_carolinensis_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI ESETDRVTGTNKGISP-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPQDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKMAKEVDP-QG-----LRTIGVMTKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKVLNQQ----LTNHIRETLPSLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSK------LGSYPRLREETERIVTTYI REREGKTKDQILLLIDIELSYINTNHEDFIGFAN---------AQQRNTQAN---KKRAIPN-----------QVIRRGW LTINNISIMK-------------------GGSKEYWFILTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQA--------------------- -------ENEEG---VQENTFSMDPQLERQVETIRNLVDSYVGIINKSIRDLMPKTIMHLMINNTKDFIHSELLAYLYSS ADQNSLMEESADQAQRRDDMLRMYHALKEALHIIGDISTSTVSTPVPPPVDDT----WLQPGGSG----HSPTPQRRP-- ----ASTVLPPGRPPA------VRGPMPGPPLIPVLSA-----GPSSFVAPPIPSRPGP-QSA-FVANNDP-----FAAP P-QIPSRPARVPP-GVPPGVPS--------------------------RRPPAAP----NRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Pelodiscus_sinensis_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEELIPLVNKLQDAFSSIGQ-SCHRALPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLIFSKT-------------------------------------EYAEFLHCKS--------KKFTDFDEVRQEI EAETDRVTGSNKGISP-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPQDIEYQIKDMILQFISRESSLILAVTPAN MDLANSDALKMAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIEGKKD IRAALAAERKFFLSHPAYRHMADRMGTPHLQKVLNQQ----LTNHIRETLPSLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLHQLVVAG--LVPPKRIEGSG---DQVDTLELSGGARINRIFHERFPFELVK--MEFDEKDLRREISYAIKNIH GIRTG------LFTPDMAFEAIVKNQIVKLKEPSLKCVDLVVSELATVIKKCAEK------LGSYPRLREETERIVTTHV REREGKTKDQILLLIDIELSYINTNHEDFIGFAN---------AQQRSTQLN---KKRAIPNQGE-------ILVIRRGW LTINNISIMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSN--- ----KHVFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQV--------------------- -------ENEDG---VQENTFSMDPQLERQVETIRNLVDSYVGIINKSIRDLMPKTIMHLMT---KDFIHSELLAFLYSS ADQSSLMEESADQAQRRDEMLRMYHALKEALHIIGDISTSTVSTPVPPPVDDG----SHCYTSFP----CSPPPQRRP-- ----TSAVLPPGRPPA------VRGPTPGPPLIVTPAGG----VSSSFVAPPIPLRPGP-QNV-FPANNDP-----FSAP P-QIPSRPARIPP-GVPPGVPS--------------------------RRPPAAP----NRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Danio_rerio_DNM2_a -------------------------------------------------------------------------------- --------MGNRGMEELIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLVNNKA-------------------------------------EYAEFLHCKG--------RKFVDFDEVRQEI EAETDRITGSNKGISP-IPINLRVYSP--NVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMIMQFITRESCLILAVTPAN MDLANSDALKVAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGRKD IRAALAAERKFFLSHPSYRHMAERMGTPHLQKALNQQ----LTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTAELSGGARINRIFHERFPFELVK--IVFDEKELRREISHAIKNVH GVRTG------LFTPDLAFEAIVKKQIIKLKEPCLKCIDLVIQELINTFRQCTNK------LSSYPRLREETERIVTTYV REREGKTKDQVLLLIDTELSYINTNHEDFIGFAN---------AQQRN-IVN---KKRAIPNQGE-------ILVIRKGW LTLN-ISIMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKLRDVEKGFMST--- ----KHIFAIFNTEQR-NVYKDLRQIELACDSQEDMD----SWKASFLRAGVYPEKDQV--------------------- -------ESEEA---APADSFSMDPQLERQVETIRNLVDSYIGIVNKTIRDLMPKTIMHLMINSAKDFIHSELLAYLYSS GDQNSLMEESADQAQRRDEMLRMYHAIKEALSIIGDISTSTISTPVPPPVNDS----WIPET--------SPTPQRRP-- ----PTSAPPPNRPPA------VRGPTPGPP---------PLNPTPSFAAPPIPSRPGQPMNAFGNSSQDP-----FSAP P-QIPSRPARIPP-GVP------------------------------SRRPPGAP----NRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Takifugu_rubripes_DNM2_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLVNSNA-------------------------------------EYAEFLHCKG--------KKFVDFEEVRAEI EAETDRITGSNKGISP-IPINLRVYSP--NVLNLTLIDLPGMTKVPVGDQPIDIENQIRDMLLQFITKESCLILAVTPAN TDLANSDALKMAKEVDP-QG-----VRTIGVITKLDLMDEGTD--AKEILENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAALAAERKFFLSHPAYRHIAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTNELLGGARINRIFHERFPLELFK--IVFDEKELRREISHAIKNVH GIRTG------LFTPDMAFEVIVKKQVVKLKTPCLKCVDLVIQELINTVRQCTSK------LGSYPRLREETERIVTTHV REREGKTKDQVLLLIDIELSYINTNHEDFIGFAN---------AQQRSTAVN---KKRAIPNQGE-------ILVIRKGW LTIN-ISIMK-------------------GGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMST--- ----KHIFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQV--------------------- -------DNED----VPADTFSMDPQLERQVETIRNLVDSYTGIINKSIRDLMPKTIMHLMINNVKDFIHSELPAYLYSS GDQNSLMEESADQAQRRDEMLRMYHALKEALHIIGDISANTISLPVPPPVNNS----WIPETRSCFP--CSPTPQRRPH- ----PTTAPPPNRPPA------VRGSTPGPPMNPSPSFGTPLNPSPAFGAPPIPSRPGPPINAF-NSSQDP-----FSAP P-LIPSRPARVPP-GVPSF---SP---------------------HCSRRPPGAPS---HRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Tetraodon_nigroviridis_DNM2_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLVNSKA-------------------------------------EYAEFLHCKG--------RKFVDFDEVRLEI EAETDRLTGSNKGISP-IPINLRVYSP--HVLNLTLIDLPGMTKVAVGDQPHDIEHQIRDMLLQFITKESCLILAVTPAN MDLANSDALKIAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAALAAERKFFLSHPSYRHMAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQGQMLSLEKEVEEYKNFRPDDPT HKTKALLQMVQQFA--VDFEKCIEGSG---DQVDTSNLSGGAKINRIFHERFPFELVK--MEFDEKELRKEISYAIKNIH GVRTG------LFTPDLAFEAIVKKQIIKLKEPCVKCIDLVIQELINTVRQCTNK------LGSFPRLREETERIVTTHI RERESKTKEQVLLLIDIELSYINTNHEDFIGFAN---------AQQRT-ASN-V-KKRVMPNQVG-------LLVIRRGW LNIN-ISIMK-------------------GGSKDYWFVLTAESLSWFKDEEEKEKKYMLPLDN-LKLRDVEKGFMSS--- ----KHIFAIFNTEQR-NVYKDLRQIELACDTQEDVD----SWKASFLRAGVYPEKDQV--------------------- -------DTEDAA--NPGDTVSMDPQLERQVETIRNLVGSYMDIVNKSITDLMPKTIMHLMINNAKDFIHSELVAYLYVA GDQSSLMEESAEQAQRRDEMLRMYHALKEALVLIGDISTNTVSTPLPPPVDDS----WIAKD---PT--QRAITCHKRS- ----YTFIFLNSVKYL------VRGHVPGPP--------PPLNPSPAFGAPPVPSRPGPGQTAYTGDSN---------AA P-HLPSRPARVPP-ALLSGNTQSL---------------------SAAEDPPAAP----NRPTVIRPSEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Gasterosteus_aculeatus_DNM2_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLVNNKA-------------------------------------EYAEFLHCKG--------KKFVDFDEVRTEI EAETERITGSNKGISP-IPINLRVYSP--HVLNLTLIDLPGMTKVAVGDQPIDIEHQIRDMLMQFITKESCLILAVTPAN TDLANSDALKIAKEVDP-QG-----LRTIGVITKLDLMDEGTD--AKDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAAMAAERKFFLSHPGYRHLAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTNELSGGAKINRIFHERFPFELVK--IVFDEKELRREISHAIKNVH GVRTG------LFTPDLAFEVIVKKQIIKLKTPCLKCIDLVIQELINTVRQCSNK------LNSYPRLREETERIVTTHV REREGKTKDQVLLLIDIELSYINTNHEDFIGFAN---------AQQRNTAAN---KKRAIPNQGE-------ILVIRKGW LTIN-ISIMK-------------------GGSKEYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKLRDVEKGFMST--- ----KHIFAIFNTEQR-NVYKDLRQVELACDSQEDVD----SWKASFLRAGVYPEKDQT--------------------- -------ENEDA---APPDTFSMDPQLERQVETIRNLVDSYIGIINKSTRDLVPKTIMHLMINSAKDFIHSELLAYLYSS GDQGTLMEESADQAQRRDEMLRMYHALKEALLIIGDISTGTISTPVPPPINDS----WRQEASISPP--LSPTPQRRPP- ----PTASAAPSRPPA------ARGATPGPPMNPSPAFGVPLNPSPAFGAPPIPSRPGPPINAF-NSHQDP-----FSAP P-MIPSRPARVPP-GVPSF---SP---------------------RCSRRPPGAPS---HRPTIIRPAEHSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Gasterosteus_aculeatus_DNM2_b -------------------------------------------------------------------------------- --------MGNRGMEDLIPLINKLQDAFSTIGQ-TCNLDLPQIAVVGGQSAGKSSVLENFV-VRDFLPR--GSGIVT--R RPLILQLVNSKV-------------------------------------EYAEFLHCKG--------RKFVDFDEVRLEI EAETDRITGSNKGISS-IPINLRVYSP--NVLNLTLIDLPGMTKVAVGDQPVDIEHQIREMLMQFITKESCLILAVTPAN TDLANSDALKISKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAALAAERKFFLSHPGYRHIAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQSQVLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTSNLSGGAKINRIFHERFPFELVK--MEFDEKELRREISYAIKNIH GVRTG------LFTPDLAFEAIVKKQIIKLKDPCLKCVDLVVTELVTLIRKCTEKGRQ---LGSYPRLREETERIVTTYV RERDSKTVSQVLLLIDIELSYINTNHEDFIGFAN---------AQQRT-AANAT-KKRVMPNQ-----------VIRRGW LTIN-ISIMK-------------------GGSKDYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKLRDVEKGFMSS--- ----KHVFAIFNTEQR-NVYKDLRQIELACDTQEDVD----SWKASFLRAGVYPEKDQP--------------------- -------ESEDAM--NPSDTVSMDPQLERQVETIRNLVDSYIGIVNKSIRDLMPKTIMHLMINSAKDFIHSELLAYLYSA GDQGSLMEESPEQAQRRDEMLRMYHALKEALVLIGDITTTTISTPVPPPVDDH----WIAKD---PS--PPPASRPAS-- -----ATAAPPSRPPG------VRGPTPGPP--------PPLNPSPAFGAPPVPSRPPG-QAAYAGDPNS-------GVT P-LIPSRPARVPP-ALPPG--------------------------IPSRRPPAAP----NRPTVARPSEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Oryzias_latipes_DNM2_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLILQLVNCKT-------------------------------------EHAEFLHCKG--------KKFVNFDEVRAEI EAETDRVTGSNKGISP-IPINLRVYSP--HVLNLTLIDLPGMTKVAVGDQPVDIEHQIREMLMQFITKESCLILAVTPAN TDLANSDALKIAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD IGAAMAAERKFFLSHPAYRHLAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQSQLLSLEKEVEEYKNFRPDDPT RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTNELSGGAKINRIFHERFPFELVK--IVFDEKELRREISHAIKNVH GVRTG------LFTPDLAFEVIVKKQIVKLKTPCLKCIDLVIQELISTVRQCTNK------LGSYPRLREETERIVSTHV REREGKTKDQVLLLIDIELSYINTNHEDFIGFAN---------AQQRNTAVN---KKRAIPNQGE-------ILVIRKGW LTIN-ISIMK-------------------GGSKEYWFILTAESLSWYKDEEEKEKKYMLPLDN-LKIRDVEKGFMSS--- ----KHSFAIFNTEQR-NVYKDLRQIELACDSQEDVD----SWKASFLRAGVYPEKDQT--------------------- -------EQEDA---APTDTFSMDPQLERQVETIRNLVDSYIGIINKSIRDLVPKTIMHLMINSAKDFIHAELLAYLYSS GDQNSLMEESADQAQRRDEMLRMYHALKEALQIIGDISVTTISTPVPPPVNDS----WIPET---RS--FSPNPQRRPP- ----VAAAPPPSRPPA------VRGPTPGPPMNPSPPFGTPLNPSPAFNAPPIPSRPGPPVSAF-NNSLDP-----FGAP PPQIPSRPARVPP-GVPRF---SP---------------------HFSRRPPGAPS---HRPTIIRPAEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Oryzias_latipes_DNM2_b -------------------------------------------------------------------------------- --------MGNRGMEELIPLINKLQDAFSSIGQ-SCNLDLPQIAVVGGQSAGKSSVLENFVGSRDFLPR--GSGIVT--R RPLILQLVNSKT-------------------------------------EHAEFLHCKG--------RKFVDFEEVRMEI EAETDRITGSNKGISP-IPINLRVYSP--NVLNLTLIDLPGMTKVAVGDQPPDIEHQIRDMLLQFITKESCLILAVTPAN TDLANSDALKIAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YIGVVN--RSQKDIDGKKD IRAALAAERKFFLSHPAYRHLAERMGTPHLQKTLNQQ----LTNHIRDTLPGLRSKLQSQLLSLEKEVEEFKNFRPDDPA RKTKALLQMVQQFG--VDFEKCIEGSG---DQVDTSNLSGGAKINRIFHERFPFELVK--MEFDEKELRKEISYAIKNIH GVRTG------LFTPDLAFEAIVKKQIIKLKEPCLKCIDLVIQELINTVRQCTNK------LGSYPRLREETERIVTTYI RERDSKTKDQVLLLIDIELSYINTNHEDFIGFAN---------AQQRT-AANAT-KKRVIPNQHAPHLSPFRFVVIRRGW LTIN-ISIMK-------------------GGSKDYWFVLTAESLSWYKDEEEKEKKYMLPLDN-LKLRDVEKGFMSS--- ----KHVFAIFNTEQR-NVYKDLRQIELACDTQEEVD----SWKASFLRAGVYPDKGQA--------------------- -------ENEDSL--TQSDMVSMDPQLERQVETIRNLVDSYISIVNKSIRDLMPKTIMHLMINNTKDFIHSELLAYLYSA GDQGSLMEESAEQAQRRDEMLRMYHALKEALLIIGDISTTTVSTPVPPPVDDT----WITKE---PS--PPPSTRHAN-- -----SMTLPPNRPPA------VRGPSSAPP--------PSLNPSPAFGVPPLPSRPGP-LQAHVGEANS-------AAA P-LVPSRPARVPP-SLPPG--------------------------IPSRRPPAAP----NRPTVVRPSEPSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Caenorhabditis_elegans_DNM2 -------------------------------------------------------------------------------- ------MSWQNQGMQALIPVINRVQDAFSQLGT-SVSFELPQIAVVGGQSAGKSSVLENFV-GKDFLPR--GSGIVT--R RPLILQLIQDRN-------------------------------------EYAEFLHKKG--------HRFVDFDAVRKEI EDETDRVTGQNKGISP-HPINLRVFSP--NVLNLTLIDLPGLTKVPVGDQPADIEQQIRDMILTFINRETCLILAVTPAN SDLATSDALKLAKEVDP-QG-----LRTIGVLTKLDLMDEGTD--AREILENKLFTLRRG-YVGVVN--RGQKDIVGRKD IRAALDAERKFFISHPSYRHMADRLGTSYLQHTLNQQ----LTNHIRDTLPTLRDSLQKKMFAMEKDVAEYKNYQPNDPG RKTKALLQMVTQFN--ADIERSIEGSSA--KLVSTNELSGGARINRLFHERFPFEIVK--MEIDEKEMRKEIQYAIRNIH GIRVG------LFTPDMAFEAIAKKQITRLKEPSLKCVDLVVNELANVIRQCADT------MARYPRLRDELERIVVSHM REREQIAKQQIGLIVDYELAYMNTNHEDFIGFSN---------AEAKASQGQ-S-AKKNLGNQ-----------VIRKGW LSLSNVSFVR--------------------GSKDNWFVLMSDSLSWYKDDEEKEKKYMLPLDG-VKLKDIEGGFM----- --SRNHKFALFYPDGK-NIYKDYKQLELGCTNLDEID----AWKASFLRAGVYPEKQKAQEDESQQ-------------- -------EMEDT---------SIDPQLERQVETIRNLVDSYMRIITKTIKDLVPKAVMHLIVNQTGEFMKDELLAHLYQC GDTDALMEESQIEAQKREEMLRMYHACKEALRIISEVNMSTLGDQPPPLPMSD----YRPHP-SGP--------SPVPRP -----APAPPG-----------GRQAPMPPRGG--------------PGAPPPPGMR------PPPGAPGGGG----GMY PPLIPTR-PGPG-----------------------------------------GPPPNMAPPR----------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Hydra_magnipapillata_DNM2 -------------------------------------------------------------------------------- --------MGNRGMEDLIPIVNKLQDAFAQIGI-ESPIDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLSYGNT-------------------------------------EYAEFLHCKN--------QKFTDFDAVRKEI EVETDRITGKTKNVSP-VPINLRIFSP--HVLDLTLIDLPGLTKIAVAGQPADIENQIRDMVYQFISKENCLILAVSPAN SDLANSDALKMAKEVDP-SG-----ERTIGVLTKLDLMDEGTD--ARDILENKVYPLRRG-YIGIVN--RSQKDIDGKKD IKAAQAAERKFFLSHPAYRHIADRMGTAFLQKALNQQ----LTNHIRECIPNLRNKLQSQVLSMEKEVEQFKNFRPDDPT MKTKALMQMLQNFT--MDIEKVIEGGSG--EDIDTEHLSGGARINRVFHERFPFELVK--LQYDEKGLRKKIAFAIRNVH GVRSG------LFTPDMAFESIVKEQIEKLKPPAIQCVDMVIAELTNIIRNCTKK------MSKYPLLQDEVVKICMTHI RSAEQKAKDQVKLLLDFELSYINTNHPDFIGFAE---------AQNRAAGDTGAPQRQRVTNQ-----------VIRKGW LLLGGGGFMK--------------------ASKEYWFTLSAENLSWYKDETERELKYQLRMEN-LKVKDLESGFMSK--- ----RVYFAIFNPDTR-NLFKDCKQLELSAESAEVVD----EWKASLLRIGVYPERNVA--------------------- ----------DDSIVDKGELGSMDPLMERQVETIRNLVESYMKIITKNIQDVIPKACMFLVVNAAKMFVSQELLAYLYAQ GNTNDLMHESDEEVNRRNEMLRIYQASKEALRIIGDISQSTMYTPTPPPVENN-----MEVDYSTSQ-----SSAYKP-- -----SMPTRPVSVSN------APRPQPDNPS---------------VPR-PAPTRPVPSQ------------------P P--QPPQPARPPP--VP------------------------------------------SRPS----------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Homo_sapiens_DNM3 -------------------------------------------------------------------------------- --------MGNREMEELIPLVNRLQDAFSALGQ-SCLLELPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------KKFTDFDEVRLEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KTTVGNQGTN-LPPSRQIVIRKGW LTISNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSVA--------------------- -------ENDEN---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDS----WIQHS-RRSP-PPSPTTQRRP-- -----TLSAPLARPTS------GRGPAPAIPS-----------PGPHSGAPPVPFRPGPLPPFPSSSDS-------FGAP P-QVPSRPTRAPP-SVP------------------------------SRRPPPSP----TRPTIIRPLESSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Pan_troglodytes_DNM3 -------------------------------------------------------------------------------- ----------------------------------------------------------------DFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------NKFTDFDEVRLEI EAETDRMTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKSAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIR----------------------QIVKLKGPSLKSVDLVIQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KTTIGNQGTN-LPPSRQIVIRKGW LTISNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSVA--------------------- -------ENDEN---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDS----WIQHS-RRSP-PPSPTTQRRP-- -----TLSAPLARPTS------GRGPAPAIPS-----------PGPHSGAPPVPFRPGPLPPFPSSSDS-------FGAP P-QVPSRPTRAPP-SVP------------------------------SRRPPPSP----TRPTIIRPLESSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Macaca_mulatta_DNM3 -------------------------------------------------------------------------------- --------MGNREMEELIPLVNRLQDAFSALGQ-SCLLELPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------KKFTDFDEVRHEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRQGR-----LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KTTIGNQGTN-LPPSRQIVIRKGW LTISNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSVA--------------------- -------ENDEN---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQAIKEALGIIGDISTATVSTPAPPPVDDS----WIQHS-RRSP-PPSPTTQRRP-- -----TLSAPLTRPTS------GRGPAPAIPS-----------PGPHSGAPPVPFRPGPLPPFPSSSDS-------FGAP P-QVPSRPTRAPP-SVP------------------------------SRRPPPSP----TRPTIIRPLESSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Mus_musculus_DNM3 -------------------------------------------------------------------------------- --------MGNREMEELIPLVNRLQDAFSALGQ-SCLLELPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------KKFTDFDEVRHEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKR------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KSTIGNQ-----------VIRKGW LTVSNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKGFMSS--- ----KHVFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSVT--------------------- -------ENDEN---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTATVSTPAPPPVDDS----WLQHS-RRSP-PPSPTTQRRL-- -----TISAPLPRPTS------GRGPAPAIPS-----------PGPHSGAPPVPFRPGPLPPFPNSSDS-------FGAP P-QVPSRPTRAPP-SVP------------------------------SRRPPPSP----TRPTIIRPLESSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Canis_familiaris_DNM3 -------------------------------------------------------------------------------- -----------------------------------------------------------FF-CRDFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------KKFTDFDEVRHEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQGQLLSIEHEVEGYKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KNTIGNQGTN-LPPSRQIVIRKGW LTISNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSLT--------------------- -------ENDEN---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALVIIGDINTATTFTPAPPPVDDS----WIQHS-RRSP-PPSPTTQRRP-- -----TLSAPLPRPAS------GRGPAPAIPS-----------PGPHSGAPPVPFRPGPLPPFPSSSSSGSGSSDWFGAP P-QVPSRPTRAPP-SVP------------------------------SRRPPPSP----TRPTIIRPLESSLLD------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Myotis_lucifugus_DNM3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------YAEFLHCKG--------KKFTDFDEVRHEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPVDIEHQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKDVDP-QG-----LRTIGVITKLDLMDEGTD--ARDILENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRNKLQAQMLSIEHEVDAYKNFKPEDPT RKTKALLQMVQQFA--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KNTIGNQGTN-LPPSRQIVIRKGW LTISNIGIMK-------------------GGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFAIFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSLT--------------------- -------ENDEN---GQAENFSLDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLHMYQALKEALVIIGDINTATTFIPAPPPVDDS----WIQHT-RRSP-PPSPTTQRRP-- -----TLSTPLARPGS------GRGPPPAIPS-----------PGPHSGAPPVPFRPGPLPPFPNSNDT-------YGAP P-QVPSRPTRAPP-SVPRP----------------------------GVRSREPP----SPPEKLCPTGSTSLS------ -------------------------------------------------------------------------------- ------------------------------------------------------------ >Monodelphis_domestica_DNM3 -------------------------------------------------------------------------------- --------MGNREMEELIPLVNRLQDAFSALGQ-SCLLELPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLVTSKA-------------------------------------EYAEFLHCKG--------RKFTDFDEVRQEI EAETDRVTGMNKGISS-IPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPQDIEYQIREMIMQFITRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YVGVVN--RSQKDIDGKKD IKAALLAERKFFLSHPGYRHIADRMGTPHLQKVLNQQ----LTNHIRDTLPNFRSKLQGQLLSIEHEVEAYKNFKPEDPT RKTKALLQMVQQFS--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFEIVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKK------LANFPRLCEETERIVANHI REREGKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVHK---KSAVGNQGTN-LPPSRQIVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEDVD----SWKASLLRAGVYPDKSLGN-------------------- ----NKADNDES---GQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALVIIGDINTSTVSTPAPPPVDDS----WLQHSSRRSP-PPSPTNQRRP-- -----TLNAPPTRPTS------GRGPAPAIPS-----------PGPQSGAPPVPFRPGPLPPFPSNSDA-------FGAP P-QVPSRPTRAPP-SVPRPHHSPLSSTVEVKKDLT--------LPSLVQEPETSQ----QVPQLNSSLSSSLLDLPDIDE FPLCPDCLRMKGEDWGSKENRETRLRGLPHFLKPSKKKMILETPAHLRVPLMDFMHDKWIQSRVKIPKDIVSEDIEAENV QYRLPMRDIWCPRKPFQTLYTDLLTHRKRTDSYKKHASPDPKSMWAEFNITKIPKHSKFH >Gallus_gallus_DNM3 -------------------------------------------------------------------------------- -------------MEGLIPLVNRLQDAFAALGQ-SCLLDLPQIAVVGGQSAGKSSVLENCV-SRDFLPR--GSGIVT--R RPLVLQLVTAKT-------------------------------------EYAEFLHCKG--------RKFTDFDEVRQEI EVETDRITGVNKGISS-IPINLRIYSP--HVLSLTLIDLPGITKVPVGDQPPDIEQQIRDMIMQFISRENCLILAVTPAN TDLANSDALKLAKEVDP-QG-----LRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD IKAALLAERKFFLSHPAYRHMADRMGTPYLQKVLNQQ----LTNHIRDTLPAFRSKLQSQLLSIEHEVEVYKNFRPEDPT RKTKALLQMVQQFS--VDFEKRIEGSG---DQVDTLELSGGAKINRIFHERFPFELVK--MEFNEKELRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQIVKLKGPCLKSVDLVMQELINTVKKCTKK------LATYPRLCEETERIVAGYI REREEKTKDQVLLLIDIQVSYINTNHEDFIGFAN---------AQQRSSQVN----KSAVGNQA---------QVIRKGW LTINNIGIMK-------------------GGSKEYWFVLTAESLSWYKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFALFNTEQR-NVYKDYRFLELACDSQEEVD----SWKASLLRAGVYPDKS----------------------- -----STENDEN---GQADNFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKEFINAELLAHLYSS EDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDISTSTVSTPAPPPVDDS----WLQQA-RRSP-PPSPSTQRRP-- -----TLNNPPTRPLS------GRGPAPAIPS-----------PGPQSGAPPVPFRPGPLPPFPSGGEA-------HGGP P-QVPSRPTRAPP-SVP------------------------------RRADTDGS----SRPDSP----PLLLDI----- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Tetraodon_nigroviridis_DNM3_a -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNRLQDAFSSIGQ-ACNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLINSTA-------------------------------------EWAEFLHCKG--------KKFTDFDEVRQEI EAETDRVTGANKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPADIEQQIRDMIMQFITRESCLILAVTPAN TDLANSDALKLAKDVDP-QG-----MRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRG-YIGVVN--RSQKDIDGKKD IKAALEAERKFFLSHPGYRHLAEKMGTPRLQKVLNEQ----LTNHIRDTLPGFRSKLQSQLLALDKEAEEYRGYRPDDPS RKTKQLLQMVQQFS--VDFEKRIEGSG---DQVDTVELSGGAKINRIFHERFPFELVK--MECDEKEMRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQVIKLKEPCVKCVDMVIQELINTVRQCSNKL------ECFPRLREETERIVTSHI RDRENRAKDQVLLLIDIQLSYINTNHEDFIGFAN---------AQQRSSQTNK--SQSSAGNQPLA-------QVIRKGW LTINNISIMK-------------------GGAKEYWFVLTAESLSWFKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFCIFNTESR-NVYKDNRTLELACDSQDDVD----SWKSSLLRAGVYPEKTVT--------------------- ------VESEST---TTADNFSMDPQLERKVETIRNLVDSYMAIVNKCIRDLMPKTIMHLMINNVKEFINAELLAQLYSA GDQNSLMDESQEQAQRRDEVLRTHQALKEALAIIGDISTTTVTVPVPPPVDTS----WVGGSG------------RRS-- ---------PPPSPTA------PRRMSSGQRP-------------APRGAPPPPNRPGPLGPFNNTADS----------- P-QAPSRPNRAPP-SIPSLF---------------------------SRPAPSQPN---TEKPSLNV------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Gasterosteus_aculeatus_DNM3_b -------------------------------------------------------------------------------- --------MGNRGMEDLIPLVNKLQDAFSSIGQ-ACNLDLPQIAVVGGQSAGKSSVLENFV-GRDFLPR--GSGIVT--R RPLVLQLISATA-------------------------------------EWAEFLHCKG--------KKFTDFDEVRQEI EAETDRVTGANKGISP-VPINLRVYSP--HVLNLTLIDLPGITKVPVGDQPVDIEQQIRDMIMQFITRESCLILAVTPAN SDLANSDALKLAKDVDP-QG-----LRTIGVITKLDLMDEGTD--AREILENKLLPLRRG-YIGVVN--RSQKDIDGRKD IKAALEAERKFFLSHSSYRHMAEKMGTPRLQRVLNEQ----LTNHIRDTLPSFRSKLQSQLLDLDKEAEEYRGYRPDDPS RKTKQLLQMVQQFS--VDFEKRIEGSG---DQVDTVELSGGAKINRIFHERFPFELVK--MECDEKEMRREISYAIKNIH GIRTG------LFTPDMAFEAIVKKQVIKLKGPCVKCVDMVIQELINTVRQCSNKL------ECFPMLREETERIVTSHI RDRESRAKDQVLLLIDIQLSYINTNHEDFIGFAN---------AQQRSSQTNK--SQSSAGNQLPSYG---CLLVIRKGW LTINNISIMK-------------------GGAKEYWFVLTAESFSWFKDDEEKEKKYMLPLDN-LKVRDVEKSFMSS--- ----KHIFCIFNTESR-NVYKDNRTLELACDSQEDVE----SWKSSLLRAGVYPEKVMA--------------------- ------VESETT---TAADNFSMDPQLERKVETIRNLVDSYMAIVNKCIRDLMPKTIMHLMINNVKDFINAELLAQLYSA GDQNALMDESQEQAQRRDEVLKTHQALKEALAIIGDISTTTITVPVPPPVDSS----WVGGPGGA----------RRS-- ---------PPSSPTA------SRRMSSGQRP-------------SPRGAPPPPNRPGPLGPFNNSADS----------- P-QAPSRPNRAPP-SIPRNP---------------------------SRRPPPSPT---RQAP----------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Homo_sapiens_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--QEDKRKTTGEEND-----PATWKNSRHLSKGVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAVSRDKS--------------------SKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGV- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Pan_troglodytes_DNM1L -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------GVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAVSRDKS--------------------SKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGV- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Macaca_mulatta_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--QEDKRKTTGEEN------------------GVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAVSRDKS--------------------SKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGV- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Mus_musculus_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGVVT--R RPLILQLVHVS--PEDKRKTTGEEND-----PATWKNSRHLSKGVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKVFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAGSRDK---------------------------------------------------------VPSAGGGIGDGG- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Canis_familiaris_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--PEDKRKTTGEEND-----PATWKNSRHLSKGVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKIFSP--HVVNLTLVDLPGMTQVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAVSRDKS--------------------YKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVAAGGGGVGDGG- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Myotis_lucifugus_DNM1L ----------------------------------------TACREWAGSSRAVTNGCRLPRRGRRRGGRRRNLGPQPVFL RGGKENGEIIFKTFKKLFSVIILAVVVLVLFGD-CVILALPLQKVLFRPSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--PEDQRKTSGEEN------------------GVEAE-EWGKFLHTKN--------KLYTDFDEIRQEI ENETERISGNNKGVSP-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKISREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSAVSRDK----------------------------------------------LIQDSRRETKNVLSGGGGVGDAV- --------QEPTTGNWRGMLKTSKAEELLAEEKSKP---IPIMPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS SLLDDLLTESEDMAQRRKEAADMLKALQGAGQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Gallus_gallus_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGVVT--R RPLILQLVHVS--PEDGRKTAGDENE------------------IDAE-EWGKFLHTKN--------KIYTDFDEIRQEI ENETERISGNNKGISP-EPIHLKIFSS--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILQFISNPNSIILAVTAAN TDMATSEALKIAREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINNKKS VADSIRDEYGFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVE DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTCLL RRRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRLAR------------------ ELPSSVPRDK-----------------------------------AAAGAGDVT-------------------------- --------QESGTGNWRGMLKSSKAEEVSAEEKSKP---AAALPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKS LLLDDLLTESEDMAQRRKEAADMLKALQRASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Anolis_carolinensis_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--ADIIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--PEDRRKTAGDEND-----PATWKNSRHLSKGVDAE-EWGKFLHTKN--------KLYTDFDEIRQEI ESETERISGNNKGISP-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAAN TDMATSEALKIAREVDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLMGRVIPVKLG-IIGVVN--RSQLDINTKKS VADSIRDEYGFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVD DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLNTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTSLL RRRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQQRRNRLAR------------------ ELPSAGSRDKS--------------------TKPPGALAPSSQETSTAGSAEVDG--------------KTSPAIGEGV- --------SESGTGNWRGMLKTSRAEEILAEEKSKP---VPVLPASPQKGHAVNLLDV---------------------- ---------------PVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDSLQSELVGQLYKA LLLDDLLTESEDMAQRRKEAADMLQALQRASQIIAEIRETHLW------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------ >Xenopus_tropicalis_DNM1L -------------------------------------------------------------------------------- -------------MEALIPVINKLQDVFNTVG--SDVIQLPQIVVVGTQSSGKSSVLESLV-GRDLLPR--GTGIVT--R RPLILQLVHVS--SDDRRKTSGDENG------------------VETE-EWGKFLHTKN--------KIYTDFDEIRQEI ENETERISGNNKGISS-EPIHLKIFSP--NVVNLTLVDLPGMTKVPVGDQPKDIEIQIRELILRYISNPNSIILAVTAAN TDMATSEALKIARESDP-DG-----RRTLAVITKLDLMDAGTD--AMDVLLGRVIPVKLG-IIGVVN--RSQLDINNKKS VADSIRDEYGFLQKK--YPSLANRNGTKYLARTLNRL----LMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVE DKSATLLQLITKFA--TEYCNTIEGTA---KYIETSELCGGARICYIFHETFGRTLES--VDPLGGLTTIDILTAIRNAT GPRPA------LFVPEVSFELLVKRQVKRLEEPSLRCVELVHEEMQRIIQHCSNY--STQELLRFPKLHDAIVEVVTSLL RKRLPVTNEMVHNLVAIELAYINTKHPDFAD-----------ACGLMNNNIEEQ-RRNRIAR---------------