>Homo_sapiens_TNF -------------------------------------------------------------------------------- ---------------------------MSTESMIRDVELA------------------------EEALPKKTGGPQGSR- ----------------------------------------RCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREE-FPRDL SLIS---------------------------PLAQAVRSSSRTPSDKPVAHVVAN-PQAEGQ------------------ ----LQWLNRRANALLANGV-----------ELR--DNQLVVPSEG--------------------LYLIYSQVLFKG-- -----QGCPS---------THVLLTHTISRIAVSYQTK--------------VNLLSAIKSPCQRETPEG-------AEA KPWYEPIYLGGVFQLEKGDRLSAE-------INRPDYLDFA-ESGQVYFG-IIAL------------------------- --------------------------------------- >Pan_troglodytes_TNF -------------------------------------------------------------------------------- ---------------------------MSTESMIRDVELA------------------------EEALPKKTGGPQGSR- ----------------------------------------RCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREE-FPRDL SLIS---------------------------PLAQAG-SSSRTPSDKPVAHVVAN-PQAEGQ------------------ ----LQWLNRRANALLANGV-----------ELR--DNQLVVPSEG--------------------LYLIYSQVLFKG-- -----QGCPS---------THVLLTHTISRIAVSYQTK--------------VNLLSAIKSPCQRETPEG-------AEA KPWYEPIYLGGVFQLEKGDRLSAE-------INRPDYLDFA-ESGQVYFG-IIAL------------------------- --------------------------------------- >Callithrix_jacchus_TNF -------------------------------------------------------------------------------- ---------------------------MSTETMIQDVELA------------------------EEALP-KTRGPQGSK- ----------------------------------------RRLFLSLFSFLLVAGATALFCLLHFGVIGPQKDE-LSKDF SLIS---------------------------PLALAVRSSSRIPSDKPVAHVVAN-PQAEGQ------------------ ----LQWLNRRANALLANGV-----------ELR--DNQLVVPSEG--------------------LYLVYSQVLFKG-- -----QGCPS---------NFMLLTHSISRIAVSYQAK--------------VNLLSAIKSPCQRETPQG-------AKT NPWYEPIYLGGVFQLEKGDRLSAE-------INLPDYLDLA-ESGQVYFG-IIGL------------------------- --------------------------------------- >Canis_familiaris_TNF -------------------------------------------------------------------------------- ---------------------------MSTESMIRDVELA------------------------EEPLPKKAGGPPGSR- ----------------------------------------RCFCLSLFSFLLVAGATTLFCLLHFGVIGPQREE-LPNGL QLIS---------------------------PLAQTVKSSSRTPSDKPVAHVVAN-PEAEGQ------------------ ----LQWLSRRANALLANGV-----------ELT--DNQLIVPSDG--------------------LYLIYSQVLFKG-- -----QGCPS---------THVLLTHTISRFAVSYQTK--------------VNLLSAIKSPCQRETPEG-------TEA KPWYEPIYLGGVFQLEKGDRLSAE-------INLPNYLDFA-ESGQVYFG-IIAL------------------------- --------------------------------------- >Felis_catus_TNF -------------------------------------------------------------------------------- ---------------------------MSTESMIRDVELA------------------------EEALPKKAGGPQGSR- ----------------------------------------RCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREE-LPHGL QLIN---------------------------PLPQTLRSSSRTPSDKPVAHVVAN-PEAEGQ------------------ ----LQWLSRRANALLANGV-----------ELT--DNQLKVPSDG--------------------LYLIYSQVLFTG-- -----QGCPS---------THVLLTHTISRFAVSYQTK--------------VNLLSAIKSPCQRETPEG-------AEA KPWYEPIYLGGVFQLEKGDRLSAE-------INLPAYLDFA-ESGQVYFG-IIAL------------------------- --------------------------------------- >Monodelphis_domestica_TNF -------------------------------------------------------------------------------- ---------------------------MSTESMIRDVELA------------------------EEALQRKAKGLQGSG- ----------------------------------------HCLFLTLISFLVLAGATILFCLLHYGVIGPQKEQDSPSAF LDMK---------------------------PLTQRVRSY-QTEINKPVAHVVAK-PTAEGK------------------ ----FQWYSGHANDLLN-GM-----------KLN--DNQLVVPATG--------------------LYLVYSQLLFKG-- -----EGCTN---------EPLLLMHTVSRVARSYPNK--------------VNLLAAIKSPCQRAAQGS-------RES NPWYEPTYLGGVFQLEKGDMLSSD-------TNYPKYLDLA-ESGQVYFG-AIAL------------------------- --------------------------------------- >Pelodiscus_sinensis_TNF -------------------------------------------------------------------------------- ---------------------------MSTESLVYDVEKG------------------------GVVVVRESQ--AGNG- ----------------------------------------CWKCLSICSFLLLTGATAVFALLQFRNEGQWVIQDFRESR -SSGQ---------------------R----AGPMTLKLQAQSLT-KPAAHVVAS-HES-KE------------------ ----LVWNDKVAHTMIQNGM-----------KL--VDNKLVVPANG--------------------LYFVYSQVVFKG-- -----NKCPE---------ESVLLRHIILRFSEEYPQD--------------VPLLTAIKSLCEGSKS---------AET EVWYESIYQGAVFQLTKGDEISSK-------IDSADYLDLD-SNGQVYFG-VIAL------------------------- --------------------------------------- >Takifugu_rubripes_TNF_a -------------------------------------------------------------------------------- -------------------------MVNYMTTAS-DVEMG---------------------LQQKTVVLVEKKSSTGWM- ----------------------------------------GKIILAIFVVVLCCGGALLFVSYWNGRQEMQAVPEKSETL IEKKD---------------------TVVVSSSDPHYTLSRISSKAKAAIHLEGSFDEGEN-RKDQ-------------- ----VEWKNGQGQAFAQGDF-----------QLD--NNTIIIPKTG--------------------LYFVYSQASFRVTC GEGDKHSPGK---------SHIPLSHRVWRYSDSIGTE--------------TTLLNAVRSACQNSALEG-----GYSEG QSCYNAIYLGAVFQLKMGDKLRTE-------TNQ--LSELETEEGKTFFG-VFAL------------------------- --------------------------------------- >Gasterosteus_aculeatus_TNF_a -------------------------------------------------------------------------------- -------------------------MVSHTTAPG-DVERG---------------------LDERMVVLVEKKPSAGRL- ----------------------------------------CKMSVAILVVALCLGGILLLAWFWPGLKKQSGQTESGQTE AMLQT---------------------KSAEK-TDHHSTLRQISSKAKAAIHLEGNYEEDDDGSQGR-------------- ----LEWKSGQGQAFAQGGF-----------RLE--GNKIVIPHTG--------------------LYFVYSQSSFRVSC GDGDEEGAGQ---------SHVPLSHRVWRYTNSLGKE--------------ASLMNAVRSACQNAPQED-----GFRDG QGWYNAIYLGAVFKLNKGDRLRTE-------TNQ--LSELETDDGKTFFG-VFAL------------------------- --------------------------------------- >Ciona_savignyi_TNF -------------------------------------------------------------------------------- --------------------MTDEKLLLSETAHPVQMCRCQHKEARADWKIAILGTFVLLLSVWCFRLNNDVGRLKLAFK ELAEIK----------------------------NSNPTPNKVLVRNSLTPAYTDAEATHSVVRRTVSDPTADETPPTRK KRGGKK--------------------------RIPKEIRRQLKKNRAIAIHVQAQGEGLGGRFR------------PELV EGRILNNWARPDRRFRGFDT-----------AHLHDDGFFTVPVTG--------------------AYFVYSQVVFNVTN HPFMTSEIGVN------------VEGQTTFSKCQFSNP--------------YTMSLGRKGASSRKK------------- ---FVTCHSNGVVFMRAREGISIS--------VNPPSVEVYLQPQFTYFG-AFLIGL----------------------- --------------------------------------- >Strongylocentrotus_purpuratus_TNF -------------------------------------------------------------------------------- ----------------MSITMSNDKQLLHPDVHCHVDVSEN-------------HKPMKMSDVQRLAMLRSKAKSESGN- --------------------------------------FSCVDFFKTLLFIATVCTFAFVFYRIAVLKQEVDSLARRFDV LRDDAYRRTNR----PCNCTVAPYFNHNRRLRRSASGTQQGSEDASGAAASANAIDPQIHSDSDRFSAHLRPAEGNTTLR EGQLFKWSAHKNHSFVEPAG-----------FELVQDQFLFVQVAG--------------------YYFIYSQITFNDSL TR--------------------TIGHQMVSWGCRSTQG--------------ATILMGTSLTQQTRPETD--------LS HTKKDSSYTGGVVYLAAGDYLAVR-----PDLGQTSKIEYARLAENTFFG-AFMIKKDARGKSLKENCFI---------- --------------------------------------- >Homo_sapiens_TNFSF14 -------------------------------------------------------------------------------- ----------------------MEESVVRPSVFVVDG-QTD------------------------IPFTRLGRSHRRQ-- -------------------------------------SCSVARVGLGLLLLLMGAGLAVQGWFLLQLHWRLGEMVTRLPD GP-AG---------------------------SWEQLIQERRSHEVNPAAHLTGANSS-------------------LTG SGGPLLWETQLGLAFLRG--------------LSYHDGALVVTKAG--------------------YYYIYSKVQLGGVG CPLGLAS---------------TITHGLYKRTPRYPEE--------------LELLVSQQSPCGRATS----------SS RVWWDSSFLGGVVHLEAGEKVVVR-------VLDERLVRLR-DGTRSYFG-AFMV------------------------- --------------------------------------- >Pan_troglodytes_TNFSF14 -------------------------------------------------------------------------------- ----------------------MEESVVRPSVFVVDG-QTD------------------------IPFTRLGRSRRRQ-- -------------------------------------SCSVARVGLGLLLLLMGAGLAVQGWFLLQLHWRLGEMVTRLPD GH-AG---------------------------SWEQLIQERRSHEVNPAAHLTGANSS-------------------LTG SGGPLLWETQLGLAFLRG--------------LSYHDGALVATKAG--------------------YYYIYSKVQLGGVG CPLGLAS---------------TITHGLYKRTPRYPEE--------------LELLVSQQSPCGRATS----------SS RVWWDSSFLGGVVHLEAGEEVVVR-------VLDERLVRLR-DGTRSYFG-AFMV------------------------- --------------------------------------- >Callithrix_jacchus_TNFSF14 -------------------------------------------------------------------------------- ----------------------MEESVVRPSVFVVDG-QTD------------------------IPFTRLGRTRRKL-- -------------------------------------SCRPAPVGLGLLVSLMGAGLAVQGWFLLQLHWRLGEMVARLPD GG-AG---------------------------SWEQLIQERRSRQVNPAAHLTGANSS-------------------LTG SGGPLLWETQLGLAFLRG--------------LSYRNGGLVATKAG--------------------YYYIYSKVQLGGVG CPQGLAS---------------TVIHGLYKRTPRYPEE--------------LELLVSQQSPCRQATS----------SS RVWWDSSFLGGVVHLEAGEEVVVR-------VLDERLVRLR-DGTRSYFG-AFMV------------------------- --------------------------------------- >Mus_musculus_TNFSF14 -------------------------------------------------------------------------------- -----------------------MESVVQPSVFVVDG-QTD------------------------IPFRRLEQNHRRR-- -------------------------------------RCGTVQVSL-ALVLLLGAGLATQGWFLLRLHQRLGDIVAHLPD GG-KG---------------------------SWEKLIQDQRSHQANPAAHLTGANAS-------------------LIG IGGPLLWETRLGLAFLRG--------------LTYHDGALVTMEPG--------------------YYYVYSKVQLSGVG CPQGLANG-L------------PITHGLYKRTSRYPKE--------------LELLVSRRSPCGRANS-----------S RVWWDSSFLGGVVHLEAGEEVVVR-------VPGNRLVRPR-DGTRSYFG-AFMV------------------------- --------------------------------------- >Canis_familiaris_TNFSF14 -------------------------------------------------------------------------------- ----------------------MEEPVVRPSVFVVDG-QTD------------------------IPFTRLGRRRRSR-- -------------------------------------PCSVAQLGLGLLLLLLVAGLAVQGWFLLRLHWRLGEMVTPLLD GD-AA----------------------------WKQLTQERRSHQASPAAHLTGANSS-------------------LTG SGGPLLWETKLGLAFLRG--------------LNYREGSLVIARAG--------------------YYYIYSKVQLGGVG CPQGLSSG-L------------PITHGLYKRTPRYPKE--------------LELLVSRRSPCGRATS-----------P RVWWDSSFLGGVVHLDAGEEVLVR-------VPDERLVRLR-DGTHSYFG-AFMV------------------------- --------------------------------------- >Felis_catus_TNFSF14 -------------------------------------------------------------------------------- ----------------------MEETVVRPSVFVVDG-QTD------------------------IPFTRLGPSRRQRQ- -------------------------------------PCSASQLGLGLLLLLLAAGLAVQGWFLLQLHWRLGEMVTPLLD GE-AE---------------------------SWKQLTQGRRSLQANPAAHLTGANSS-------------------LTG SGGPLLWETKLGLAFLRG--------------LSYRDGSLVIARAG--------------------YYYIYSKVQLGGVG CPQGLTSG-L------------PITHGLYKRTPRYPEE--------------LELLVSRRSPCGRATG-----------P RVWWDSSFLGGVVHLDAGEEVVVR-------VPDERLVRLR-DGTRSYFG-AFMV------------------------- --------------------------------------- >Monodelphis_domestica_TNFSF14 -------------------------------------------------------------------------------- ------------------------DPVIHPSVFVVDG-QTD------------------------MPFTRLGGSKQRA-- --------------------------------------CQRTQLGLGLLLLLALAGVAIEGYFLWSFHWDLMALSLRLPV SEPAH---------------------------SLEKLVQERRSYQDKPAAHLTGVNSS-------------------LVM NGGPLLWEAHLGLAFLRD--------------LKYQKGSLVCTQPG--------------------YYYIYSKVQLGGVG CPGGPMAG-G------------SVTHGLYKRTPRYPKD--------------LELLVSRRSSCRWTGT----------SA KVWWDSSFLGGVVHLEAGEEVFVR-------VPEERLVRVK-DGTRSYFG-AFMV------------------------- --------------------------------------- >Anolis_carolinensis_TNFSF14 -------------------------------------------------------------------------------- ----------------------METGVGYPSVFVVDAPQRN------------------------VPFVPPVPKGRKK-- --------------------------------------WQHAQLLLWVFMLLMLIGLMVQGYFLLSFRKELTKATTQG-- GAEAP---------------------------TYEKIVQGERPPKEKPAAHLTLGALI-------------------NTA ENGALLWEDKKGLAFLQD--------------MGYKDGVLIFNQSG--------------------HYYIYSKLLLGDSR CPSASQM----------------VIHEICKRTSRYPRE--------------IVLLTNKILTCNLQNT------------ PGWRHNSFLAGMVHLEENEEVFVK-------VSHKQMVRVG-DDTRSYFG-TFMI------------------------- --------------------------------------- >Homo_sapiens_TNFSF15 -------------------------------------------------------------------------------- --------------------MAEDLGLSFGETASVEMLPEH-----------------------GSCRPKARS------- ---------------------------------------SSARWALTCCLVLLPFLAGLTTYLLVSQLRAQGEACVQFQA LKGQEF------------------APS------HQQVYAPLRADGDKPRAHLTVVRQTPTQHF---------------KN QFPALHWEHELGLAFTKN-------------RMNYTNKFLLIPESG--------------------DYFIYSQVTFRGMT SECSEIRQAGR------PNKPDSITVVITKVTDSYP-EP-------------TQLLMGTKSVCEVGSN------------ --WFQPIYLGAMFSLQEGDKLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Pan_troglodytes_TNFSF15 -------------------------------------------------------------------------------- --------------------MAEDLGLSFGETASVEMLPEH-----------------------GSCRPKARS------- ---------------------------------------SSARWALTCCLVLLPFLAGLTTYLLVSQLRAQGEACVQFQT LKGQEF------------------APS------HQQVYAPLRADGDKPRAHLTVVRQTPTQHL---------------KN QFPALHWEHELGLAFTKN-------------RMNYTNKFLLIPESG--------------------DYFIYSQVTFRGMT SECSEIRQAGR------PNKPDSITVVITKVTDSYP-EP-------------TQLLMGTKSVCEVGSN------------ --WFQPIYLGAMFSLQEGDKLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Callithrix_jacchus_TNFSF15 -------------------------------------------------------------------------------- --------------------MAENLGLSCGETASVEMLPEQ-----------------------DSCRPKARS------- ---------------------------------------RGPCWALTCCFLLLPFLAGLTTYLLVSQLRTQGETCVQFQT LKEQEF------------------APS------HQQVYSPLRADGDKPRAHLTVVKQTPTQHL---------------KN QLPALHWEHELGLAFTKN-------------RMSYTNRFLLIPESG--------------------DYFIYSQVTFRGMT SQCSEIRQAGQ------LNKPDSITVVITKVTDTYP-EP-------------TQLLMGAKSVCEVGSN------------ --WFQPIYLGAMFSLQEGDKLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Mus_musculus_TNFSF15 -------------------------------------------------------------------------------- --MGGSLVRRDQKSLQDSRRMAEELGLGFGEGVPVEVLPEG-----------------------CRHRPEARAGLAAR-- ---------------------------------------SKACLALTCCLLSFPILAGLSTLLMAGQLRVPGKDCM-LRA ITEERS------------------EPS------PQQVYSPPR---GKPRAHLTIKKQTPAPHL---------------KN QLSALHWEHDLGMAFTKN-------------GMKYINKSLVIPESG--------------------DYFIYSQITFRGTT SVCGDISRGRR------PNKPDSITMVITKVADSYP-EP-------------ARLLTGSKSVCEISNN------------ --WFQSLYLGATFSLEEGDRLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Rattus_norvegicus_TNFSF15 -------------------------------------------------------------------------------- --MGGSLARRHQKYPQDSRSMAEELGLGFGEAVPVEMLPEG-----------------------CRHRREARTGLAAR-- ---------------------------------------SKACLALTCCLLSFPILAGLSTLLMTGQLRIPGKDCM-FPT VTEERS------------------APS------AQPVYTPSR---DKPKAHLTIMRQTPVPHL---------------KN ELAALHWENNLGMAFTKN-------------RMNYTNKFLVIPESG--------------------DYFIYSQITFRGTT SECGDISRVRR------PKKPDSITVVITKVADSYP-EP-------------AHLLTGTKSVCEISSN------------ --WFQPIYLGAMFSLEEGDRLMVN-------VSDISLVDYT-KEDKTFFG-AFLI------------------------- --------------------------------------- >Equus_caballus_TNFSF15 -------------------------------------------------------------------------------- --------------------MAEHLGLGFGETASVEMLPED-----------------------GSCGPHARARLAARRS S--------------------------------------SSACWALTCCLVALPILAGLTTYLLVGQLRAQGEASM-LAS LKEEKL------------------SPS------PTQGEQSP--RGHKPRAHLTVVRQTPTQPM---------------KN QFPALHWEHELGLAFTKN-------------RMNYTNKFLVIPEQG--------------------DYFVYSQVTFRGTT SECGEIGQGSR------LNKPDSIIVVITKVTDSYP-EP-------------TQLLMGTKSVCEIGSN------------ --WFQPIYLGAMFSLQEGDKLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Monodelphis_domestica_TNFSF15 -------------------------------------------------------------------------------- --------------------MPKGKGSALEPEPRVEMLQEE-----------------------GGDHGTNHSTRRDQ-- ---------------------------------------RKMNPAVTFCMLLVFILTVLIIYLLVDNVRSQQKMCASGQF PKALGS------------------ERL------YQRAYTPHRSNSDKPRAHLTAIRQNPMTPM---------------KD SWPALQWEHKLGSAFVKN-------------QMNYTNKFLVIPESG--------------------DYFVYSQVTFRGST PECGKINQKDR------STKPDYITQVITRVTDRYP-EP-------------TQLLTGTKSICEIGSN------------ --WFIPIYLGAVFPMQEGDKLMVN-------VSDISLVDYT-KEDKTFFG-AFLL------------------------- --------------------------------------- >Gallus_gallus_TNFSF15 -------------------------------------------------------------------------------- --------------------MDHGAEITLEEASATG-QASR-----------------------MHIKEDLRR------- -----------------------------------------MRCAVLLCLLAVLLLALPIAYLLAGNLRAPTSC-PQVVD ERSSHF------------------LKQR-----AVAAVTDTLPSAEKPRAHLTVKKQEPSSTT---------------GS HLPILQWEDKRGLAFTKN-------------NLSYSSNALVIPVSG--------------------DYYVYAQVTFRGPS DTS---------------SKTSSVTAVITKVTDSYP-EP-------------TQLLTSTKTLSEERNN------------ --WFQPIYLGAVVSLEIGDKLMVN-------VSDIKLVDYT-KEHKTFFG-AFLL------------------------- --------------------------------------- >Taeniopygia_guttata_TNFSF15 -------------------------------------------------------------------------------- --------------------MESAAEMG-AEAAGSG-HGAG-----------------------LRLRQDLRR------- -----------------------------------------IRCALLLCLLAVLLLMLPTAYLLVGNLRAPSSCGSQVTE ERGSHF------------------LKQR-----AVAAVTDTLSSAEKPRAHLTVKKQDLASAV---------------GS HLPILQWEDKRGLAFTKN-------------NLSYSSNALVIPVSG--------------------DYYVYAQVTFRGPV ESS---------------HKASSVTEIITKVTDSYP-EP-------------TQLLTGTKTLSENGNG------------ --WFQPIYLGAVVSLEVGDKLMVN-------VSDIKLVDYT-KEHKTFFG-AFLL------------------------- --------------------------------------- >Xenopus_tropicalis_TNFSF15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------KPRAHLTGKKQYSYVS------------------ KDQALQWENSNGLAFTNN-------------GMNYTNEGLEIPKTG--------------------YYFVYSQVTFRLPT YTAG------K------KSKTEHVSLTVKKITSKYP-EP-------------EKLISGAKNVNENESE------------ --GYRPIYLGALLLLEAKDQLIVE-------VSDIQLVDVT-VEHKTFFG-AFML------------------------- --------------------------------------- >Danio_rerio_TNFSF15_b -------------------------------------------------------------------------------- -----------MVSMTS------SHTMQYIGLLLLAAILLQ------------TIAVAVTFIYFSNVLSTMKETFSKSSV SCL----------------------MRANLRTIKGQELNGAEGKDDPCWQVTQQLHFLIEKSMSSRYQKEITSAVKDEVS RVLPS-----------------------------LVIQDQEDSSRPKIAAHVTGSY-------TPESEKDGAGLPNRKVY GQKIQSWESEKGLAFLQN--------------VELSDGELVVPQAG--------------------LYYIYSQTYFRHTL IEEDESAREDEYGSMGESVRGKPMLQYVYKKVSSYQVP--------------ILLMKNARTTCWSR------------DS EYGLYSIYQAGLFQLGSGDRVFVT-------VSNVSTIDMD-E-KSSFFG-AFLVS------------------------ --------------------------------------- >Takifugu_rubripes_TNFSF15_b -----------------------------------------------------------------MATPSAQQHQDYFRS VSSESTTYMMVPAGGANGTRRREAPSKMWVAMVVLVVVVLQ------------IASTTGLFLYLNMSISQVRSQGVTEEL KCLS---------------------LLNALHKDPDIPDQLAQLLGEPCMKLAEGIKAYISKVTENIISKQTFIEARNMPR IFNTSG----------------------------SKLSPVTQRPSAHLTLRDTNSQ--------GFPSYPSNTPGLHQSC RHVVRSWANQSFGAHLHN--------------MTLTNGKLRVPQDG--------------------RYYLYSQVYFRYPS PAASDGD---------QRSVSHQLVQCVYKKTS-YPSP--------------IQLLKGVGTKCWAP------------DA EYALHSVYQGGLFELRAGDELFVS-------VSSPTMVNAD-D-SSSYFG-AFRLDL----------------------- --------------------------------------- >Homo_sapiens_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPERLFLPRVCG- ----------------------------------------TTLHLLLLGLLLVLL-PGAQGLPGVGLTP----SAAQTAR QHPK----------------------------------MHLAHSTLKPAAHLIGDPSKQNS------------------- ----LLWRANTDRAFLQDGF-----------SLS--NNSLLVPTSG--------------------IYFVYSQVVFSGKA YS---PKATS---------SPLYLAHEVQLFSSQYPFH--------------VPLLSSQKMVYPGLQ------------- EPWLHSMYHGAAFQLTQGDQLSTH-------TDGIPHLVLS--PSTVFFG-AFAL------------------------- --------------------------------------- >Pan_troglodytes_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPERLFLPRVRG- ----------------------------------------TTLHLLLLGLLLVLL-PGAQGLPGVGLTP----SAAQTAR QHPK----------------------------------MHLAHSTLKPAAHLIGDPSKQNS------------------- ----LLWRANTDRAFLQDGF-----------SLS--NNSLLVPTSG--------------------IYFVYSQVVFSGKA YS---PKATS---------SPLYLAHEVQLFSSQYPFH--------------VPLLSSQKMVYPGLQ------------- EPWLHSMYHGAAFQLTQGDQLSTH-------TDGIPHLVLS--PSTVFFG-AFAL------------------------- --------------------------------------- >Callithrix_jacchus_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPERLFLSRVQG- ----------------------------------------TPLHLLLLGLLLALL-PGAQGLPGVGLTP----SASQIAR QHPK----------------------------------MHLARSTLKPAAHLVGDPSNQKS------------------- ----LRWRANTDRAFLQDGF-----------SLS--NNSLLVPTSG--------------------IYFVYSQVVFSGNA YS---PKATP---------TPLYLAHEVQLFSSQYPFH--------------VSLLSSQKMVYPGLQ------------- EPWLHSMYHGAAFQLTQGDQLSTH-------TDGIGHLVLS--PSTVFFG-AFAL------------------------- --------------------------------------- >Mus_musculus_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTLLGRLHLLRVLG- ----------------------------------------TP-PVFLLGLLLALP-LGAQGLSGVRFS------AARTAH PLPQ----------------------------------KHLTHGILKPAAHLVGYPSKQNS------------------- ----LLWRASTDRAFLRHGF-----------SLS--NNSLLIPTSG--------------------LYFVYSQVVFSGES CS---PRAIP---------TPIYLAHEVQLFSSQYPFH--------------VPLLSAQKSVYPGLQ------------- GPWVRSMYQGAVFLLSKGDQLSTH-------TDGISHLHFS--PSSVFFG-AFAL------------------------- --------------------------------------- >Rattus_norvegicus_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPLGRLHLLRVLS- ----------------------------------------TP-PVFLLGLLLALP-LGAQGLSGVRFS------ASRTAH QPPQ----------------------------------KHLTHGLLKPAAHLVGYPSKQNS------------------- ----LLWRANTDRAFLRHGF-----------SLN--NNSLLIPTSG--------------------LYFVYSQVVFSGES CS---PRAIP---------TPIYLAHEVQLFSSQYPFH--------------VPLLSAQKSVYPGLQ------------- GPWVRSMYQGAVFLLSKGDQLSTH-------TDGISHLHFS--PSTVFFG-AFAL------------------------- --------------------------------------- >Canis_familiaris_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPGRLYLLRVRS- ----------------------------------------AP-VLLLLGLLLGLP-PGAQGFPGVGISP----SAARTAY QHPQ----------------------------------KHFIQGTLKPAAHLIGDPSIQNS------------------- ----LRWRANTDRAFLRHGF-----------SLS--NNSLLVPTSG--------------------LYFVYSQVVFSGEG CF---PKATP---------TPLYLAHEVQLFSSQYPFH--------------VPLLSAQKSVCPGPQ------------- GPWVRSVYQGAVFLLTQGDQLSTH-------TDGISHLLLS--PSSVFFG-AFAL------------------------- --------------------------------------- >Felis_catus_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPGRLYLLRVCS- ----------------------------------------APLLLLLLGLLLALP-PEAQGLPGVGISP----SAARTTY QHPQ----------------------------------KHFAQGTLKPAAHLIGDPSTQNS------------------- ----LRWRANTDRAFLRHGF-----------SLS--NNSLLVPTSG--------------------LYFVYSQVVFSGEG CF---PKATP---------TPLYLAHEVQLFSSQYPFH--------------VPLLSAQKSVCPGPQ------------- GPWVRSVYQGAVFLLTQGDQLSTH-------TDGISHLLLS--PSSVFFG-AFAL------------------------- --------------------------------------- >Pteropus_vampyrus_LTA -------------------------------------------------------------------------------- -----------------------------------------------------------------MTPPGYLYLMRVCG- ----------------------------------------APLLLLLLGLLLALP-PEAQGLPGVGLSP----SIARTVH QHPQ----------------------------------NHFAQGTFKPAAHLVGDPSTQNS------------------- ----LRWRANTDRAFLRHGF-----------SLN--NNSLLVPTSG--------------------LYFVYSQVVFSGEG CF---PKATP---------TPLYLAHEVQLFSSQYPFH--------------VSLLSAQKSVCPGPQ------------- GPWVRSVYQGAVFLLTQGDQLSTH-------TDGISHLLLS--PSTVFFG-AFAL------------------------- --------------------------------------- >Homo_sapiens_FASLG -------------------------------------------------------------------------------- --------------------MQQPFNYPYPQIYWVDSSASS-----------PWAPPGTVLP-CPTSVPRRPGQRRPPPP -----PPPPPLPPP---PPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQ MHTAS-------------------SLEKQ----IGHPSPPPEKKELRKVAHLTGKSNS---------------------- RSMPLEWEDTYGIVLLSG--------------VKYKKGGLVINETG--------------------LYFVYSKVYFRGQS CN-NLPLS-----------------HKVYMRNSKYPQD--------------LVMMEGKM-MSYCT------------TG QMWARSSYLGAVFNLTSADHLYVN-------VSELSLVNFE-E-SQTFFG-LYKL------------------------- --------------------------------------- >Pan_troglodytes_FASLG -------------------------------------------------------------------------------- --------------------MQQPFNYPYPQIYWVDSSASS-----------PWAPPGTVLP-CPTSVPRRPGQRRPPPP -----PPPPPLPPP---PPPP-LPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQ MHTAS-------------------SLEKQ----IGHPSPPPEKKELRKVAHLTGKPNS---------------------- RSMPLEWEDTYGIVLLSG--------------VKYKKGGLVINETG--------------------LYFVYSKVYFRGQS CN-NLPLS-----------------HKVYMRNSKYPQD--------------LVMMEGKM-MSYCT------------TG QMWARSSYLGAVFNLTSADHLYVN-------VSELSLVNFE-E-SQTFFG-LYKL------------------------- --------------------------------------- >Callithrix_jacchus_FASLG -------------------------------------------------------------------------------- --------------------MQQPFNYPYPQIYWVDSSASS-----------PWAPPGTVLP-CPTSVPRRPGQRRPPPP -----PPPPPLPPP---PPPP-LPPLPLPPLKKGGTHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESASQ RHAVS-------------------SVEKQ----IGHPSPPPERKELRKVAHLTGKPNS---------------------- RSMPLEWEDTYGIVLLSG--------------VKYKKGGLVINETG--------------------LYFVYSKVYFRGQS CN-NLPLS-----------------HKVYMRNSKYPQD--------------LVMMEGKM-MSYCT------------AG QMWARSSYLGAVFNLTSADHLYVN-------VSELSLVNFE-E-SQTFFG-LYKL------------------------- --------------------------------------- >Mus_musculus_FASLG -------------------------------------------------------------------------------- --------------------MQQPMNYPCPQIFWVDSSATS-----------SWAPPGSVFP-CPSCGPRGPDQRRPPP- -----PPPPVSPLP---PPSQPLPLPPLTPLK-KKDHNTNLWLPVVFFMVLVALVGMGLGMYQLFHLQKELAELREFTNQ SLKVS-------------------SFEKQ----IANPSTPSEKKEPRSVAHLTGNPHS---------------------- RSIPLEWEDTYGTALISG--------------VKYKKGGLVINETG--------------------LYFVYSKVYFRGQS CN-NQPLN-----------------HKVYMRNSKYPED--------------LVLMEEKR-LNYCT------------TG QIWAHSSYLGAVFNLTSADHLYVN-------ISQLSLINFE-E-SKTFFG-LYKL------------------------- --------------------------------------- >Rattus_norvegicus_FASLG -------------------------------------------------------------------------------- --------------------MQQPVNYPCPQIYWVDSSATS-----------PWAPPGSVFS-CPSSGPRGPGQRRPPP- -----PPPPPSPLP---PPSQPPPLPPLSPLK-KKD-NIELWLPVIFFMVLVALVGMGLGMYQLFHLQKELAELREFTNH SLRVS-------------------SFEKQ----IANPSTPSETKKPRSVAHLTGNPRS---------------------- RSIPLEWEDTYGTALISG--------------VKYKKGGLVINEAG--------------------LYFVYSKVYFRGQS CN-SQPLS-----------------HKVYMRNFKYPGD--------------LVLMEEKK-LNYCT------------TG QIWAHSSYLGAVFNLTVADHLYVN-------ISQLSLINFE-E-SKTFFG-LYKL------------------------- --------------------------------------- >Loxodonta_africana_FASLG -------------------------------------------------------------------------------- --------------------MWQPLNYPYPQIYWVDSSSSS-----------PLAPPGSALP-CPSSVPGRPGQ------ ------------------------------MKKRRNPNTGLYLLVMFFMVLVALVGLGLGLFQLFHLQKELAELRESTRL SPVAS-------------------SLEKQ----IGQPSLPSEKREVKKVAHLTGNPNS---------------------- RSIPLEWEDTYGIALVSG--------------VKYKKGGLVINDTG--------------------LYFVYSKVYFRGHS CN-NQPLN-----------------HKVYMRNSKYPQD--------------LVLMEERM-MNYCT------------TG QMWARSSYLGAVFNLTIADNLYVN-------VSELSLVNFE-E-SKTFFG-LYKL------------------------- --------------------------------------- >Pteropus_vampyrus_FASLG -------------------------------------------------------------------------------- --------------------MQQPLNYPYPQIYWVDSSASS-----------PWAPPGSVLP-CPASAPRRPGQRRPPP- -----PPPPPLPPTLLPPLPPLPPPPPPPPLKKSRDHNTGLCLLVMFFMILVALVALGLGMFQLFHLQRELAELRESTSQ RHVAS-------------------SLEKQ----IGRPSPPSEKKEPRKVAHLTGKPNS---------------------- RSMPLEWEDTYGIALVSG--------------VKYKKGGLVINDTG--------------------LYFLYSKVYFRGQS CS-NQPLS-----------------HKVYMRNSKYPHD--------------LVLMEGRM-MNYCT------------TG QMWARSSYLGAVFNLTCADHVYVN-------VSELSLVSFE-E-SKTFFG-LYKL------------------------- --------------------------------------- >Gallus_gallus_FASLG -------------------------------------------------------------------------------- --------------------MQQNLNYMYPQIFWVDGCADAS---------TSCHPASPVAP-FPPPVPDRRKK------ ------------------------------PKS-SKERSSVSFLVIFLLILLALTGAGLSMFQIFHLEKELAELRESVNA DRIPP-------------------ALEKL----IGQESKPVK-KEARKAAHLTGNPTQ---------------------- RNLPLEWEPVSGHAFTSG--------------IQYRDQGLVINETG--------------------LYFVYSNVLFRGRH CD-NEVLT-----------------HVVYKRNPASPGS--------------HVLMEDKR-INYCT------------KE KMWARKSYLGALFKLRERDSLYVN-------VSRIDLVNSE-E-SKTFFG-LFKL------------------------- --------------------------------------- >Taeniopygia_guttata_FASLG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------LILVASPEVGLSIFKIFHLEKEVDELRESASP EHIPP-------------------ASQKL----TGELQIPRQGKEVRRAAHVTGNPAQ---------------------- RDLPLEWEPTSGHAYTSG--------------IQYQNRGLLVSEPG--------------------LYFVYSQVLFRGSA CD-SQLLS-----------------HVVYKRNPASPGS--------------LVLMEDKA-TNFCK------------DQ RMWARNSYLGALFKLRKMDSLHVN-------VSKIALVNFE-E-SKTFFG-LFKL------------------------- --------------------------------------- >Anolis_carolinensis_FASLG -------------------------------------------------------------------------------- --------------------MHQNQQCMYPQVFWTSSSAVSS---------SDYAPSGLFLN---GILPRQDIFPSPPAP --------------------------ERKRNKQNTRDGTCLCFLVVFLMTLLALSGAGLAIFQVSHLQLELKALKEQGSQ EVVPA-------------------SLENN----IVLNGTADLKFKSR--AHLTGKANQ---------------------- DSLPLEWESTYGHAFISG--------------VRYENRGLMIAEAG--------------------VYFVYSKVFFRGQA CT-TKPLY-----------------HVVFKRNPSYPGI--------------QLLMEDRK-MSYCR------------AT HMWGKSSYLGALFNLSRQDSLHVN-------VSDVLLVNSE-E-SKTFFG-LYML------------------------- --------------------------------------- >Xenopus_tropicalis_FASLG -------------------------------------------------------------------------------- --------------------LKLQHNTKTSAAHYVDFRLTN-----------PIMQQDMRYA-QPSVFWTDPCRTPPLPP -----LPPNQVNMP--------LPPPFPDFRRKRRKDGTCTYLLIMFLLILLALFGVGLGTYKIIELQKELDNVKEISGD QALPP-------------------ALEKL----IGLNKHPTEKKESRLAAHVTGKEGKE-----------------GKEG PTLPLAWEETFGRAFTSG--------------IQYKNRGLVVNQTG--------------------LYFLYSSIYFRSTS CQ-SKELS-----------------HTVYKKSKRYPGE--------------LILMQNTE-YQYCT------------SN NKWGRHSYLGSLFNFTMDETIYVN-------VSDVKLVGFD-E-SRTFFG-LYKL------------------------- --------------------------------------- >Danio_rerio_FASLG_a -------------------------------------------------------------------------------- --------------------MSANFGHSSQPVFMVDSAGNHPKQHRYYHQQVPRHPEPPLVP-CWTFPP----ARVEMK- -------------------------------KKGWGGMNAGLAWVVTLILLLVFAALGLGAYQILRLQTKLEQLTQELPT IMQSSA------------------PQK---QVGLNPAELK--KNKYKSAAHLIGYAEQ--------------------SK SPGLLKWISNHGDAFTDG--------------VKYTDGGLQVNETG--------------------LYFVYSRVEFLSHT CKTFDSLA-----------------HKISLKRNG--NS--------------QIIMEDNI-EGFCMTS----------KN HPWVTGSQLGSLQQLRELDWLFVN-------VSRPHLLSKN-F-HSNYFG-LFKIH------------------------ ---------------------------------------