>Homo_sapiens_CAMSAP1 -----------------------------------------MVDASGRAAAEGWR--KMEAPPDGAADLVPLDRYDAARA KIAANLQWI-CAKAYGRDN---------------------------IPEDLRDPFYVDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTESDLSRAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEVKLKQ QLLES----PAHQKSPSKWYWKLV------------------------------------------PVRYRREHLSARQS PYFPLLED---------LMRDGSDGAALLAVIHYYCPEQMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------TVLHQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAGTLAELQPPVQLPAEGCHRHYLHPEEPEYLG----------------------------------- ------------------------KGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLTRVDGQPRGAAIAWPE-- ----------------KKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLASNIVNLTPQNQPHP-------- ---------------------------------------------------TATKSHGKSLLSNVSIED-EEEE------ -------------------------------------------------LVAIVRADVVPQQADPEFPRASPRALGLTAN ARSPQGQLDTSESKP-DSFFLEPLMPAVLKPAKEK-QVITKEDERGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------IVSRRPSEGPQPLVRRKMTG---SRDLNRTFTPIPCSEFPMGIDPT--ETGP-----------------L SVETAGEVCGGPLALGGFDPFPQGPSTDGFFLHVGRADEDTEGRLYVSC------------------------------- ------------------------SKSPNSHDSEP-WTLLRQDSDSDVVDIEEAEHDFM-GEAHPVVFSRYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTASQMSSVS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPS----------------------------------------QHGKDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAE-----------------------------AAP-PLRPEHFAKE YS-----------------QHNGEDCGDA--VSKTEDFLVKEEQREELLHEPQDVDK----ESLAFAQQHKAKDPVALHE LERNKVISAALLEDTV-----------GEVVDVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTVPVPG---------SKNNSQ--DHKVKA----------------------------PVHFVEP- LSPTGVAGHRKAPRLG----------QGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVE--TLPHLRPFPASSHPRTPT DPGLDSALEPSGDPHGKCLFD-----------------------------------------------SYRLHDESNQRT ------------------------------LTLSSSKDANILSEQMSLKEVLDASVKEVGSSSSDVSGKESVPVE----- ----------------------------------------EPLRSRASLIEVDLSDLKAPDEDGELVSLDGSA------- DLVSEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSRTQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMEALPILSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKNITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKAQTRK--------- >Pan_troglodytes_CAMSAP1 -----------------------------------------MVDASGRAAAEGWR--KMEAPPDGAADLVPLDRYDAARA KIAANLQWI-CAKAYGRDN---------------------------IPEDLRDPFYVDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTESDLSRAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEVKLKQ QLLES----PAHQKSPSKWYWKLV------------------------------------------PVRYRREHLSARQS PYFPLLED---------LMRDGSDGAALLAVIHYYCPEQMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------TVLHQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAGTPADLQPPVQQPAEGCHRHYLHPEEPEYLG----------------------------------- ------------------------KGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLTRVDGQPRGAAIAWPE-- ----------------KKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLASNIVNLTPQNQPHP-------- ---------------------------------------------------TATKSHGKSLLSNVSIED-EEEE------ -------------------------------------------------LVAIVRADVVPQQADPEFPRASPRALGLTAN ARSPQGQLDTSESKP-DSFFLEPLMPAVLKPAKEK-QVITKEDERGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------IVSRRPSEGPQPLVRRKMTG---SRDLNRTFTPIPCSEFPMGIDPT--ETGP-----------------L SVETAGEVCGGPLALGGFDPFPQGPSTDGFFLHVGRADEDTEGRLYVSC------------------------------- ------------------------SKSPNSHDSEP-WTLLRQDSDSDVVDIEEAEHDFM-GEAHPVVLSRYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTASQMSSVS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPS----------------------------------------QHGKDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAE-----------------------------AAP-PLRPEHFAKE YS-----------------QHNGEDCGDA--VSKTEDFLVKEEQREELLHEPQDVDK----ESLAFAQQHKAKDPVALHE LERNKVISAALLEDTV-----------GEVVDVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTVPVPG---------SKNNSQ--DHKVKA----------------------------PVHFVEP- LSPTGMAGHRKAPRLG----------QGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVE--TLPHLRPFPASSHPRTPT DPGLDGALEPSGDPHGKCLFD-----------------------------------------------SYRLHDESNQRT ------------------------------LTLSSSKDANILSEQMSLKDVLDASVKEVGSSSSDVSGKESVPVE----- ----------------------------------------EPLRSRASLIEVDLSDLKAPDEDGELVSLDGSA------- DLVSEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSRTQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMEALPILSRNASRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKNITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKAQTRK--------- >Gorilla_gorilla_CAMSAP1 -------------------------------------------------------------------------------- ------------------N---------------------------IPEDLRDPFYVDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTESDLSRAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEVKLKQ QLLES----PAHQKSPSKWYWKLV------------------------------------------PVRYRREHLSARQS PYFPLLED---------LMRDGSDGAALLAVIHYYCPEQMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------TVLHQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAGTPADLQPPMQLPAEGCHRHYLHPEEPEYLG----------------------------------- ------------------------KGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLTRVDGQPRGAAIAWPE-- ----------------KKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLASNIVNLTPQNQPHP-------- ---------------------------------------------------TATKSHGKSLLSNVSIED-EEEE------ -------------------------------------------------LVAIVRADVVPQHADPEFPRASPRALGLTAN ARSPQGQLDTSESKP-DSFFLEPLMPAVLKPAKEK-QVITKEDERGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------IVSRRPSEGPQPLVRRKMTG---SRDLNRTFTPIPCSEFPMGIDPT--ETGP-----------------Q SVETAGEVCGGPLALGGFDLFAQGPSTDGFFLHVGRADEDTEGRLYVSC------------------------------- ------------------------SKSPNSHDSEP-WTLLRQDSDSDVVDIDEAEHDFM-GEVHPVVLSRYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTASQMSSVS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPS----------------------------------------QHGRDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAE-----------------------------AAP-PLRPEHFAKE YS-----------------QHNGEDCGDA--VSKTEDFLVKEEQREELLHEPQDVDK----ESLAFAQQHKAKDPVALHE LERNKVLSAALLEDAV-----------GEVVDVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTVPVPG---------SKNNSQ--EHKVKA----------------------------PVHFVEP- LSPTGVAGHRKAPRLG----------QGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVE--TLPHLRPFPASSHPRTPT DPGLDGALEPSGDPHGKCLFD-----------------------------------------------SYRLHDESNQRT ------------------------------LTLSSSKDANILSEQMSLKEVLDASVKEVGPSSSDVSGKESVPVE----- ----------------------------------------EPLRSRASLIEVDLSDLKAPDEDGELASLDGSA------- DLVSEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSRTQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMEALPILSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKNITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKAQTRK--------- >Macaca_mulatta_CAMSAP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------MADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDVK---------------TVLHQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAGTPADLQPPAQLPADGCHRHYLHPEEPEYLG----------------------------------- ------------------------KGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLTRVDGQPRGAAIAWPE-- ----------------KKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLASNIVNLTPQNQPHP-------- ---------------------------------------------------TAVKTHGKSLLNNVSIED-EEEE------ -------------------------------------------------LVAIVRADVAPQQADLEFPRASPRASGLIAS ARSPQGQLDTSESKP-DSFFLEPLMPAVLKPAKEK-QVITKEDERGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------ITSRRPSEGAQPLVRRKVTG---SRDLNRTFTPIPCSEFPMGIDPT--ETGP-----------------Q SVETMGEVCGGPLALGGFDPFPQGPSTDGFFLHVDRADEDTEGRLYVSC------------------------------- ------------------------SKSPNSHDSEP-WTLLRQDSDSDVVDIEEAEHDFL-GEAHPVVLSRYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTASQMSSVS----------VASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPG----------------------------------------RHGRDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAE-----------------------------AAL-SLRPEHFSKE YS-----------------QHNGEDCGDG--VSKTEDFLVKEEQREELLHEPQDVDK----ESLAFAQQHTAKDPVALHE LERNKVISAALLEDTV-----------GEVVDVNECDLSIEKLNETISALQ--------------------------QAI LKISQQQEQLLLKSPTVPVPG---------SKSNSQ--DHKGKA----------------------------PVHFVEP- LSPTGVAGHRKAPRLG----------QGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVE--TLPHLRPFPASSHPRTPT DPGLDGALEPSGDPHGKCLFD-----------------------------------------------SYRLHDESNQRT ------------------------------LTLSSSKDTNILSEQMSLKEVLDASVKEAGPSSSDVSGKESIPVE----- ----------------------------------------EPLRSRASLIEVDLSDLKAPDEDGELASLDGSA------- DLISEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSRTQSGSSLSLASAAT---------------- ---TEPESIHSGGTPSQR----VESMEALPILSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEATLEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKNITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKGQTRK--------- >Mus_musculus_CAMSAP1 -----------------------------------------MVDAGGRCAAEGWR--RMEAPPEG-ADLVPLDRYDAARA KIAANLQWI-CAKAYGLDN---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVATLQG--HQSVIQALSR------------KGIYVMESDDTPVTDADLSQAP-I------------KM SGHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEVKLKQ QPLES----PAHQK-----------------------------------------------------VRYRREHLSARQS PYFPLLED---------LMRDGSDGAALLAVVHYYCPEQMKLDD------------------ICLKEVPSMADSLYNIRL LREFSNEH--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDIQELKDAK---------------TVLQQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAMSPADQPPSTQPLAEGSHRYHLHSEEPECLG----------------------------------- ------------------------KGASTFSPSHPLLPLRQKQQKVSQTEEIPDQRHRSNSLTRVDGQPRGAIGAWPD-- ----------------KKNRPVSQPTSFALHHAASCDVDPSSGDSVSLARSISKDSLASNIIHLTPQNQPHP-------- ---------------------------------------------------SAGKSNGKSLLSNVNIED-EDEE------ -------------------------------------------------LVAIIRTDVSPP--SPQMPRTSPQAPGLVAS IRSPQRQADTLESKP-DSFYLEPLMPAVLRPAKEK-QITTKEDERGEGRPRT---------------------------- -------------------------------------------------------------------------------- ----------IMAKRPSEGSQPMVRKKVSGGHGSRDLNRTFTPIPCSEFAASIDLA--EVGP-----------------Q SAEATGE--GQPLALGRFDTLPQGQAADGFFLHVGRAEED-EGRWYVG-------------------------------- ------------------------SQSPSSHDSEP-WTILRQDSDSDVVDVEDTEQDFI-GEDHPVVIPRYAGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTTSQLSSMS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPG----------------------------------------RHSKDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAD-----------------------------GAPQPLRPEHFTKE FT-----------------QHNGEDLDDG--TCKTEGFLVKEEQRD--LSDAQDV---------AFVQLHKPRDPAALHD GEKHRMISTALLEDSV-----------GEV-DVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTVPTPG---------TKNNCQ--DQKIKA----------------------------PVHFVEP- LSPTGVPGHRKPPRLG----------QGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVE--TLPQSRSLPPSTHPRSPS DP--------GGELPEKCLFD-----------------------------------------------SYRLHDESNHRT ------------------------------FVLSSCKDANIVSEQVNFKEGLDTSVKEAGLSSSTITGKEHTPVE----- ----------------------------------------EPLRSKASLIEVDLSDLKAPDEDGEVVGHESSV------- ELGGDSDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARARKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESYSDSGTKCSS--------------T-HNLSQTHSGSSLSLASAAT---------------- ---TEPESVYSGGTPSHR----VESLEALPILSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPTVPKKTQTRK--------- >Rattus_norvegicus_CAMSAP1 -----------------------------------------MVDAGGRSAAEGWR--RMEAPPEG-ADLVPLDRYDAARA KIAANLQWI-CAKAYGLDN---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQAATLQG--HQSVIQALSR------------KGIYVMESDDTPVTDADLSQAP-I------------KM SGHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEVKLKQ QPLES----PAHQKPGLEHAVMHCMLEPVDFAR---------------------------------VVRYRREHLSARQS PYFPLLED---------LMRDGSDGAALLAVVHYYCPEQMKLDD------------------ICLKEVPSMADSLYNIRL LREFSNEH--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDIQELKDAK---------------TVLQQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLG----------------------------------- ------------------------KGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPD-- ----------------KKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHP-------- ---------------------------------------------------SAGKTNGKSLLSNVNIEDDEEEE------ -------------------------------------------------LVAIIRTDVSPH--SPEIPRTSPQAPGLVAS IRSPQRQADTLESKP-DSFYLEPLMPAVLRPAKEK-QIITKEDERGEGRPRT---------------------------- -------------------------------------------------------------------------------- ----------IMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPT--EVGP-----------------Q STEATGE--GQPLALGRFDPVPQGQVADGFFLHVGRAEED-EGRWYVG-------------------------------- ------------------------SQSPSSHDSEP-WTILRQDSDSDVVDVEDAEQDFI-GEDHPVVIPRYAGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTTSQLSSMS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWRQKREQSPS----------------------------------------RHSKDPASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAD-----------------------------GAPQPLRPEHFTKE FT-----------------QHNGEDLDDG--TCKTEGFLVKEEQRD--LSDSQDV---------AFVQLHKPRDPATLHD GEKHRVISAALLEDSV-----------GEV-DVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTVPTSG---------TKNNCQ--DQKVKA----------------------------PVHFVEP- LSPTGVPGHRKPPRLG----------QGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVE--TLPHSRSLPPSTHPRSPL DP--------GGELPEKCLFD-----------------------------------------------SYRLHDESNHRT ------------------------------FGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPME----- ----------------------------------------EPLRSKASLIEVDLSDLKAPDEDGEVVGHESSL------- ELGGESDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARARKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSQTHSGSSLSLASAAT---------------- ---TEPESVHSGGTPSHR----VESLEALPILSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPTVPKKTQTRK--------- >Canis_familiaris_CAMSAP1 ----------------------------------------------------------MEAAPDGAVDIVPLDRYDSARA KIAANLQWI-CAKAYGIDN---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTDPDLSHAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWVN--KVNLKMREITEKEVKLKQ QLLES----PAHQKSPSKWYWKLV------------------------------------------PVRYRREHLSTRQP PYFPLLED---------LMRDGSDGAALLAVVHYYCPEHMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQEPKDAK---------------TVSHHKSSRP---------------------------------- ----------------------------------------------------------------------------PIPI SNATKRSFLGSPAVASPADPQPPTQPPAEGGPRQRLRPEEPEHLG----------------------------------- ------------------------KGASAFSPSHPLLPLRQRQQKAVQGEGPPDQRHRSNSLTRVDGQPRGAAVAWPE-- ----------------KKNRPVSQPAPFALHHAASCDMDPGSGDSVSLARSISKDSLASNVINLTPQNQPQP-------- ---------------------------------------------------TTLKADGQSLLNNVDIED-EDEE------ -------------------------------------------------LVAIIRTDVAPHGGERGLPTS---------- ARSPHRLADTLESKP-DSFFLEPLMPAVLRPAKEK-QAIAKEEECGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------FTSKRPSEGHQPLVRKRAPSSHGSRDLSRTFTPIPCPELPVGMDPVPTETG------------------- -PQAAGDGRGGLLATGGFDLLPQGQSTDGFFLHVARADEDGEGRFCVGC------------------------------- ------------------------ARSPGAHDLEP-WPVLRQDSDSDVADLDEAEQDLI-GEDHPVLMGRYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTVSQVSSVS----------MASGSVRMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWKQRREQSPN----------------------------------------RQSREHASLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAD-----------------------------SAPQPRKPDHLTGD YA-----------------QHNGEDFDGG--VSRTEEFLLKEEGREGVLP-SPDVDT----ESLVLLQ-HKVKAPATLHE LEKTKVLSAALLED-A-----------GEAVDVSECDLSIEKLNETISTLQ--------------------------QAI LRISQQQEQLLMKPPAAPAPG---------TKPNTQ--DQKVRT----------------------------AIHFVEP- LSPPGTTGHRKPPRLGQG--------QGRNSRSGRPAELKVPRDRQQASSRSKTPTPSIE--TLPHLRSFPP----RTPS DPGWDSVAEPGNDPHEKCFFD-----------------------------------------------SYRLHDESNQRT ------------------------------FVSPSSKDANILSEQMSLKEVLDSSVKEAGLSSPAVSGKENIPAD----- ----------------------------------------EPPRGKASLIEVDLSDLKAPDEDGETEGPQSSV------- DLTSEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKGKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TSDHLSRAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESLEALPTLSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKTQTRK--------- >Felis_catus_CAMSAP1 -------------------------------------------------------------------------------- ---------------GSDN---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTDPDLSHAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWVN--KVNLKMREITEKEVKLKQ QLLES----PAHQK-----------------------------------------------------VRYRREHLSARQP PYFPLLED---------LMRDGSDGAALLAVVHYYCPEQMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------TVSHHKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAASPADLQPPAALPAEGGHRHRLHPEEPEHLG----------------------------------- ------------------------KGASAFSPSHPLLPLRQRQQKTAQGEGLPDQRHRSNSLTRVDGQPRGAAVAWPE-- ----------------KQNRPVSQPAPFALHHAASCDLDPGSGDSVSLARSISKDSLASSVINLTPQNQPQP-------- ---------------------------------------------------AALKTDGKSLLNDVHIED-E--E------ -------------------------------------------------LVAVIRTDVAPHGGDRGLPAS---------- ARSPQRLADTLERKP-ETFFLEPLMPAVLRPAKEK-QAIAKEDECGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------FASKRPSEGHQPLVRKRAPSSHGGRDPTRTFTPISCPEPPAGVDPVPAETG------------------- -PQAVSD----------FDPSPRGQSADGFFLHVARAADDAEGRFCISC------------------------------- ------------------------ARSPGAHDPEP-WAVLRQDSDSDVADLEEAEQDLV-GEDHPVVMAGYVGEEESAKL QEDMKVREHEDK--DDASG---------------------RSSPCLSAVSQVSGVS----------AASGSVKMTSFAER KLQRLNSCETR------------------------------------------------SSTSSSQKTTPDAS----ESC PAPLTTWKQRREQSPG----------------------------------------GPSADHASLLASELVQLHMQLEEK RRAIEAQKREVEALSARQRLKLGKAAWA---------------------------------------------------- --------------------------------SGTEELAAKEEGREGALQ-SPDVDA----ESPVFLQ-HKATAPAAPHE LEKGRALSAALLED-A-----------GQAVDASECDLSIEKLNETISTLQ--------------------------QAI LRISQQQEQLLMKPPAAPAPA---------PGPKHGGPDQQVRA----------------------------AIHFVEP- LSPPGTAAHRKPPRLG----------QARNSRSGRPAELKVPKDRQ-ASSRSKTPTPSVE--SLPHLRPCPP----RTPS DPGWDGVAEPGGDPPEKYFFD-----------------------------------------------SYRLHDEHNQRT ------------------------------LVLSSSKDANILSEQMSLKEVLESGVKEVGLGCPSVSGKENVPVD----- ----------------------------------------EAPRGKASLIEVDLSDLKAPDEDGETEGPQSAV------- DLAGEGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARMRKQQLEAE----VELKRDEARR-------- ---------------------KAEEERIRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKAKPR-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDHLSRAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQRR---VESLEALPTLSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEICKLAGTGPKSIAKKMVDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKTQTRK--------- >Bos_taurus_CAMSAP1 -----------------------------------------MVDAGGCPAGEGWR--RMEAAPDGAVDIVPLDRYDPARA KIAANLQWI-CAKAYGRDD---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVASLQG--HQSVIQALSR------------KGIYVMESDDTPVTEPDLSHAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWVN--KVNLKMREITEKEVKLKQ QLLES----PAHQK-----------------------------------------------------VRYRREQLCARQP PHFPLLED---------LMRDGSHGAALLAVVHYYCPGQLKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------SVSYPKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAASPADLQLGEPEPPPAAGDFSLPS--SLFRG----------------------------------- ------------------------KGASAFSPSHPLLPLRQKQQKTVQGEDPPDQRHRSNSLTRADSQPRGAAIAWTE-- ----------------KKNRPVSQPAPFALHHTASCDMDPGGGDSVSLARSISKDSLASSVVHLTPQNQPQP-------- ---------------------------------------------------AALRTDGRSLLSNVDIED-EDEE------ -------------------------------------------------LLAIVRTDVARQGGDPGPMAG---------- ARSPHRLADAFESKT-DSFFLEPLMPAVLRPAKEK-QVVTKEDECGEGRPRA---------------------------- -------------------------------------------------------------------------------- ----------FTSRRSGDGHQPLGRKKAPSSHVARDLNRTFSPISCSEMSAGFEAVPAEVG------------------- -PQVAGDTHGGSLAGSSFDPSSQGQSADGFFLHVGRADKDAEGRLYMSC------------------------------- ------------------------ARSPGALSPDT-WAVLRQDSDSDVADLDEAEQDFA-GEEHPAVRAGYGGEEESAKL QEDLKVKEHDDK--DDASG---------------------RSSPCLSTVSQTSSAS----------MASGSAKMTSFAER KLQRLNSCETK------------------------------------------------SSASSSQKTTPDAS----ESC PAPLTTWKQRREQSPS----------------------------------------RPGGDHASLLASELLQLHMQLEEK RRAIEAQKKKVEALSARQRLQLGKAAFLHVVKKGRAD-----------------------------ATQQPLKVGSLAGE HA-----------------QHNG------------DDFLGKEEGRGALLG-SPDVDG----EGLALVQPHKARDPASLPE LEHGKALSAVLLED-------------TEGVDVGECDLSIEKLNETISTLQ--------------------------QAI LRISQQQEQLLLKSPTLPSPG---------PRNGAQ--DPKAKA----------------------------AIHFVEP- LSPTALTGHRKPPRLG----------QGRNARSGRPAELKVPKERQQGSSRSKTPTPGLE--TAPHSRSFPP----RTPP EPGWDGPSEPGSEASEKCVFD-----------------------------------------------SYRLHDESNQRT ------------------------------LVLSSSRDANVLSEQGGFREGLEGSAKEAGLSTLPAPGKENVPLD----- ----------------------------------------EPPRSKASLIEVDLSDLKAPDEDGETEGRDSSV------- DLGSEGDQKPGVGFFFKDEQKA-DDELAKKRAAFLLKQQR---KAEEARVRRQQLEAE----VELKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKTRPR-- -------KPRPKSVHREEPGSDLGPKSAS--------------PPDNLSRAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESLEALPVLSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEICKLTGTGPKSIAKKMIDKLYKYSSDRKQFS-LIPAKTMSVSVDALTIHNHLW QP---KRPSAPKKTQTRK--------- >Equus_caballus_CAMSAP1 -------------------------------------------------------------------------------- ---------------GSDN---------------------------IPEDLRDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVTDPDLSRAP-I------------KM SAHMAMVDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWVN--KVNLKMREITEKEVKLKQ QLLES----PARQK-----------------------------------------------------VRYRREHLSARQP PCFPLLED---------LMRDSSDGAALLAVVHFYCPEQMKLDD------------------ICLKEVTSMADSLYNIRL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQELKDAK---------------TVSHQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLGSPAAASPADLQSSTQLPAEGCPRHHLHPEESEHLG----------------------------------- ------------------------KGASAFSPSHPLLPLRQKQQKTMQGEECPDQRHRSNSLTRVDGQPRGAAAAWAE-- ----------------KKNRPVSQPAPVALHHAASCDLDPGSGDSVSLARSISKDSLASNIVNLTPQNQPHP-------- ---------------------------------------------------TALKTNGKSLLNNVDIED-EDEE------ -------------------------------------------------LVAIIRTDVAPHSGDLGLMAS---------- ARSPQRLADTLESKP-DSFFLEPLMPAVLRPAKEK-QMITKEDECGEGRPRS---------------------------- -------------------------------------------------------------------------------- ----------FTSKRSSEGYQPLLRKKASSGHVSRDLNRTFTPI-CSELPVGLDPVPAEAG------------------- -PQVVGEACGRPLASGGFDPLSQGQSADGFFLHVARAEEDTEGRFYVSC------------------------------- ------------------------AKSPNAHHPEP-WTVLRQDSDSDIADLEEAEHDLL-GEDHPVVITKYVGEEESAKL QEDLKVKEHEDK--DDASG---------------------RSSPCLSTVSQISSVS----------MASGSVKMTSFAER KLQRLNSCETK------------------------------------------------SSTSSSQKTTPDGS----ESC PPPLTTWKQRREQSPS----------------------------------------RQSKDHASLLASELVQLHMQLEEK RRAIEAQKKKMETLSARQRLKLGKAAFLHVVKKGKAD-----------------------------VVPQPLKPEHFARE YS-----------------QHNGEDFDGG--VSKMEEFLVKEEGREDLLSESQDVDR----ESLAFIQQHKPKDPATLHD LEKHKALSAALLEDSA-----------GEVGDVSECDLSIEKLNETISTLQ--------------------------QAI LKISQQQEQLLMKSPTAPAPG---------SKNNSQ--DQRVKT----------------------------AIHFVEP- LSPTGVTGHRKPPRLG----------QGRNSRSGRPADLKVPKDRQQGSSRSKTPTPSIE--TLPHLRSFPP----RTPS DPGWDGGADPGSDPQEKCFFD-----------------------------------------------SYRLHDESNQRT ------------------------------FVLSSSKDANIILEQTSLKEALDGGEKEAGLSAPAGSGKENGPVD----- ----------------------------------------EPPRSKASLIEVDLSDLKAPDEDGETEGHESSV------- DLSTDGDQKPGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARVRKQQLEAE----VELKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESCSDSGTKCSS--------------TPDNLSRAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESLEALPVLSRNPSRSTDRDWETASAASSLAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAVSHCCLAGKVNEPHKNSILEA-REKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAAPKKTQTRK--------- >Gallus_gallus_CAMSAP1 ------------------------------------------MVDVDVGAGGESGRRKMDALGDSAVEIVPLELYDSARA KIAANLQWI-CAKAYGIDN---------------------------VPEELKDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVSESDLGCAP-I------------KM SSHMAMIDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEIKLKQ QLMES----PGHQK-----------------------------------------------------VRYRRDHLSSRQL PYFPLLED---------LMKDGSDGAALLAVIHYYCPEQMKLDD------------------ICLKEVTSIADSLYNIQL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNIMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDVQEIKDVK---------------TVLQQKNSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFMASPASTNPADVQPSAQAGSEACSRYYLHPEEPDCLISG--------------------------------- -----------------------KAGSPAFSPSHPLLPLRQKQQKSLQGEDSPGHRHRSNSLTRVDGQPRGSVLAWPE-- ----------------KKPRPLSQPTPFALHHSASTDVDPGSGDSISLARSISKDSLASNIVNVTPKNQPHP-------- ---------------------------------------------------PSMKTNGKSLLNNVEIED-EDEE------ -------------------------------------------------LIAIIRSEERPNRGDVELQNAAARVPSIVAT AWSPKINSESSESKP-DSFYLEPLMPAVLKPAKEK-QIINKEDECGEGKQRS---------------------------- -------------------------------------------------------------------------------- ----------FITKRLNEGHLPLIRKKTSSSHGDHDLSRTFTPISSSDFSPVTESSAADS-------------------V ALVEAGLEASRPLASSSLDPSAQDQPTGGFFLHAAKSDDDIASKVNVSY------------------------------- ------------------------VKGLNLHVPDTTWTMVRQDSDSDLLDIEDTEQDLVVLDDHPI-VAKYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTISQVSSVS----------VASGSVRMTNFAER KLQRLNSYETK------------------------------------------------SSTSSSQKTTPDGS----ESC PAPLTTWKQKREQSPS----------------------------------------RPNKDNVNLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKSP-----------------------------DVPQPLKPEHFPKE YP-----------------RHNGEDLDEVSLGSKSEEYFVKEEEREDIINDSQEVTKVKMQESLPFVEQHKPKDSAAIHE LEKSKIISAALLEDS------------VTEVDINECDLSIEKLNETISTLQ--------------------------QAI LKISQQQE-LLMKSPSVPSPG---------TRSNSQ--DQKVKP----------------------------SIHFVEP- LSPTGMNSLRKPPRFG----------QGRSPRSGRPADLKVPKDRQQNSARVKTPTQSLE--SLPHLRPFPSNSLSKTPT EVGSENSPDLGSGTQEKCFFD-----------------------------------------------TYRLHDESNQRA ------------------------------LVLSTSKDANIISEMS---KEVNNSFKETGLNSSDGSGKENVPMD----- ----------------------------------------EPLRSKANLIEVDLSDLKAPDE-GELENQDSSA------- DIISEGDQKSGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARLRKQQLEAE----VEQKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRKKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESYSDSGTKCSS--------------TPDNLSSAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMESLPILSRNPSRNTERDWENASTASSIAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-VIPAKTMSVSVDALTIHNHLW QA---KRPAVPKKTQTRK--------- >Taeniopygia_guttata_CAMSAP1 --------------------------------------------------------RKMDALTDSAVEIVPLELYDSARA KIAANLQWI-CAKAYGIDN---------------------------VPEELKDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYVMESDDTPVSESDLGSAP-I------------KM SSHMAMIDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREITEKEIKLKQ QLMES----PGHQK-----------------------------------------------------VRYRRDHLSSRQL PYFPVLED---------LMKDGSDGAALLAVIHYYCPEQMKLDD------------------ICLKEVTSIADSLYNIQL LREFSNEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDIQEIKDVK---------------AVMQQKSSRP---------------------------------- ----------------------------------------------------------------------------PVPI SNATKRSFLATPASPSPAELQPPAQAAPEACSRYYLHPEEPDYLG----------------------------------- -----------------------KGGSPAFSPSHPLLPLRQKQQKSLQGEDSPGHRHRSNSLTRVDGQPRGAVLAWPE-- ----------------KKPRPLSQPTPFALHHSASTDVDPGSGDSISLARSISKDSLASNIVNVTPKNQPHP-------- ---------------------------------------------------PSVKANGKSLLNNVEMED-EDEE------ -------------------------------------------------LIAIIRSEERPNRGDPEVQNAAARVPSIVAT TWSPKTNSDPSDSKP-ESFYLEPLMPAVLKPAKEK-QVINKEDECGEGKQRS---------------------------- -------------------------------------------------------------------------------- ----------FVTKRLNEGHLSLIRKKATSSHGEHDLNRTFTPISSSDFTPVADPSSADA-------------------M ALGEAGVEASRPLASSSLDPSSQELSAGGFFLHAAKPDDEVTSKVSVSY------------------------------- ------------------------GKGLSLHVQDATWTMVRHDSEPDLLDMDDADQDLVAIDNHPI-VTKYIGEEESAKL QEDMKVKEHEDK--DDASG---------------------RSSPCLSTISQVSSVS----------VASGSVRMTSFAER KLQRLNSYETK------------------------------------------------SSTSSSQKTTPDGS----ESC PAPLTTWKQKREQSPN----------------------------------------RQNKDNVNLLASELVQLHMQLEEK RRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKSP-----------------------------DGPQPLKPEHFAKE YS-----------------RHNGEDLDEVSLGSKSEEFLVKEEEREEMLNDSQEVAK----ESLAFAEQHKPKDPAAIHD LEKSKIISVALLEDN------------VTEADINECDLSIEKLNETISTLQ--------------------------QAI LKISQQQE-LLMKSPTVPSPG---------SRNNSQ--DQKVKP----------------------------SIHFVEP- LSPTGMNSLRKPPRLG----------QGRTPRPGRPSELKVPKDRQQNSARVKTPTPSLE--NLPHLRPFPPNSLAKTPT EVGLESSPDHGSGSQEKCFFD-----------------------------------------------TYRLHDESNQRA ------------------------------LVLSTSKDANILSEMS---KEVNNSFKETGLNSSDGSGKENVPVD----- ----------------------------------------EPLRSKANLIEVDLSDLKAPDE-GELENQDSST------- DMISEGDQKSGVGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARLRKQQLEAE----VEQKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRKKQQQILEEQ------------GLGKPKSKPK-- -------KPRPKSVHREESYSDSGTKCSS--------------TPDNLSSAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMESLPILSRNPSRNTERDWENASTASSIAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFN-VIPAKTMSVSVDALTIHNHLW QA---KRPAVPKKSQTRK--------- >Anolis_carolinensis_CAMSAP1 ------------------------------------------MVDADVCAGGDSTRRKMDALTDSAAEIVPLELYDSARA KIAANLQWI-CAKAYGIDN---------------------------IPEELKDPFYIDQYEQEHIKPPVIKLLLS-SELY CRVCSLILKGDQVAALQG--HQSVIQALSR------------KGIYAMESDDSPVSELDLASAP-I------------KM SPHMGMIDALMMAYTVEM-ISIEKVVASVKCFSTFSAS------KDLPYDLEDAMIFWIN--KVNLKMREITEKEIKLKQ QLLES----PGHQKSPSKWYWKLV------------------------------------------PVRYRRDHLSSRQL PFFPLLED---------LMKDCSDGAALLAVIHYYCPEQMKLDE------------------ICLKEVTSIADSVYNIQL LREFANEY--LN-KCFYLTLEDMLYAPLVLKPNVMVF-----IAELFWWFEI-VKPDFVQP------------------- -----------RDLQEVKDAK---------------TMLQQKSSRP---------------------------------- ----------------------------------------------------------------------------PIPI SNATKRSFMASPAASSVAEVQPPTQLPLETCN-----------SG----------------------------------- ------------------------KGSPAFSPAHPLLPLRQKQQKSLQGEDSSGQRNRSNSLTRVDGQPRDSILAWPE-- ----------------KKQRPLSQPTPFVLHHAASSDADPSYGDSISLARSISKDSLASNIINITPKQHPQS-------- ---------------------------------------------------VPPKSSGRSLLSNVEIED-EDEE------ -------------------------------------------------LIAIIRPDAAPNQGGLELQSVPARSPGGVAT AWASK--SETSESKP-ESFFLEPLMPAVLRPAKEK-QIINKEDECGEGKMRG---------------------------- -------------------------------------------------------------------------------- ----------FGAKRLTEGHT--VRKKTNGSHGDHNLNRTFNVTPSPELTTAVSSSLADP-------------------A LHLELRPETFRPQASSSLEPSTRDQSFGGFFLHAAKTEEDAMTGANASY------------------------------- ------------------------VKTPDSYATESTWTMVRQDSDSDILDMEEAEQDLIADDHPII--AKYIGEEESAKL QEDMKVKEHEDK--DDGSG---------------------RSSPCLSTISQVSSVS----------MTSGSARMTSFAER KLHRLNSYETK------------------------------------------------SSTSSSQKTTPDGS----ECC PAPLTTWKQKREQSPN----------------------------------------RQSKDNVNLLASELVQLHMQLEEK RRAIEAQKKKMETLSARQRLKLGKAAFLHVVKKGKVA-----------------------------DVSQPLKPEHFTKE YS-----------------RHNGEGLDDASLTSKSEAFFMREEGGEDSL-DSLEAAKVKAQETVAFVEQNNPKE-PTLHE IEKSKMISAALLEEN------------IESSDVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQE-LLMKAPTMPS-----------SRGGSQ--DQKIRA----------------------------PVHFVEP- LSPTGMSSLRKPPRLG----------QGRSSRSGRPSELKVVKERQQTTARIKTPTPSVD--TLPHLRQFPSNNTAKTPT EMTVENN----TTPQEKLSFE-----------------------------------------------SYRLCDESNQRG G-----------------------------FTFSSPKDTNILSEAI---KDVNSNVEDFSLASFEGSGKETVPAE----- ----------------------------------------ESQRSKSSLIEVDLSDLKGPDE-GEVESQGS--------- ----EIDQKSGLGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEETRLRKLQLEAE----VEQKRDEVRR-------- ---------------------KAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQ------------GLGKPKPKPKP- ------KKARPKSVHREESYSDSGTKCST--------------TPDNLSSAQSGSSLSLASAAT---------------- ---TEPESVHSGGTPSQR----VESMESLPILSRNPSRNMERDWENTSTASSIAS------------------------- -------------------------------------------------------------------------------- --------------------------VAEYT-GPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEE-LEKCDA NHYIILFRD-AGCQFRALYCYYPDTEEIYKLTGTGPKSIAKKMIDKLYKYSSDRKQFN-LIPAKTMSVSVDALTIHNHLW QP---KRPAVPKKTQTRK--------- >Xenopus_tropicalis_CAMSAP1 ------------------------------------------MVDVGLSASGDGTRRKMESLADGTVEVVPLDMYDSFRA KIAANLQWI-CAKAYGIVD---------------------------VALSAHNRMAHPIYSLSHDSP-RLSLCLS--ERN TRLLACSIAGTALAELQF--PASSIIILSRF-----------QAVCVLKASAAPWDNICLPSAA-F------------AQ SAHMSMIDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPYDLEDAMVFWIN--KVNLKMREILEREHRIKQ QVIES----PSHPK-----------------------------------------------------IRYRRDHPSNRHL PYFPILED---------LMKDISDGAALLTIIHFYCPEQMKLDD------------------ICLKEVTSIADSLYNIQL LKEFSNEY--LN-KCFFLTLEDMLYSPLVLKPNVMVF-----IAELFWWFEN-VKPDFVQP------------------- -----------RDTQELKEAK---------------VATQPKSSRP---------------------------------- ----------------------------------------------------------------------------QVPI SNATKRSFLASPPSTG----DCQAAAASDSCSRNYLQPEDAENGK----------------------------------- -------------------------GCTVFSPSHPLLPLRQKQQKSVQPEESPSKSNSHKQIRPITGEHQGAGISSGDQ- ----------------KRDKPLSQP--FGFHHGAD-DVDATSGDSISLARSISKDSLASNIISATPKHQTFP-------- ---------------------------------------------------TPMNVGSKSLLGNVDIED-DEEE------ -------------------------------------------------LVAFIRSDDTSCPGDLELQSVSSRASSQMSA TRPRR--PGDLESKP-DSFFLEPLMPAVLKPAKEK-QMVPKREEYGEGKQKG---------------------------- -------------------------------------------------------------------------------- ----------FSSKRQNEGNQSFSRKKIINNHTGHDLNRTFTPLSSLESACVTAPLRTDPAQ------------------ LSIENGNGTFRPLATSSVEPN---EPVGGFFLHD-INDDEVEEKPSVGS------------------------------- ------------------------LMIEDPRKSDTTWTVLP---DSEHLDIGEREQEVV----VARAFGKHIGEEESAKL QEDMKVKEHDDK--DDASG---------------------RSSPCLSTISQISSAS----------MASGSIRMTSFAER KFQRLNSYETK------------------------------------------------SSTSSSQKTTPDGS----ECC PLPLTTWKQRREQSPG----------------------------------------RQNKDHANVLASELVQLHMQLEEK RRAIEAQKKKMESLSARQRLKLGKAAFLHVVKKGKPD-----------------------------TVPQPVKPGHSLKD YT-----------------KRVPEDIDAVSVNAKVEQYLETIEPGDLKVQEAFADPK--------------QKDPASLEA DICN--LIASSTPDDA-----------DSEIDVNECDLSIEKLNETISTLQ--------------------------QAI LKISQQQE-MLMKAPAMAVPP---------LPNNGQ--EHKLKP----------------------------SVQFVEP- ISPPGVPVARKTPRFG----------QGRNPRSLRIPEQKTAKEKALSSSRVITPTNSIE--TVPHLKSVQPPKSPNLPA EEPPADIVPEQDKPTTG---------------------------------------------------GFRLHEDNNQRT ------------------------------FVLSASKDANIISEQMHR--EAVASLRVAGGSAPESSGKENVPVD----- ----------------------------------------EQNKNKSSLIEVDLSDLKETDEEGEETDHPEKT------- KDIISDDQKSGLGFFFKDEQKA-EDELAKKRAAFLMKQQR---KAEEARIRKQQLEAE----VEQKRDEARR-------- ---------------------KAEEDRIRKDEEKARRELIKQEYLRRKQQQILEEQ------------GLGRPKPKPKP- ------RKTRPKSVHREESYSDSGTKYSS--------------TPDNLSSAQSGSSLSLASGAT---------------- ---TEAESVHSGGTPSHR----YTQGSGYSMNRKNIRLSRNMTFTSVDCVDSLSF------------------------- -------------------------------------------------------------------------------- --------------------------FLFPS-GPKLYKEPSSKSNKPIIHNAISHCCLAGKVNETVKNSTLEE-LEKCDS NHYIILFRD-AGCQFRALYSYYPDTEEICKLMGTGPKNITKKMIDKLYKYSSDRKQFT-VIPAKTMSASVDALTIHNHLG KP---RGPXLPKKNPLCK--------- >Danio_rerio_CAMSAP1_a ------------------------------------IADGGLGMDAELGADSARRKMEAAG---EALEIVPLEMYDSARA KIAANLRWL-FAKAFGIDH---------------------------IPEDLRDPFYRDQYEQEHIKPPVIRLLLS-CELY CRVCALILKGDQVASLQS--HQSVIQALSR------------KGIYVMEDDDTPVTDSDLTCQP-I------------KM SSHIPMIDALMMAYTVEM-ISIEKVVSCVKRFSTFSAS------KELPFDLEDAMIFWIN--KVNLKMREITEKEHKSKQ HLLES----PSHQKSPSKWYWKLV------------------------------------------PVRYRRDHASGRQL PYFQMLED---------LIRDVCDGAALLTVVHYYCPELMKLDD------------------ICLKEVTSIADSLYNIQL LKEFANEY--LN-KSFYLTLEDLLYAPPVLKHNVMVF-----IAELFWWFEI-VKPEFVQP------------------- -----------RDVQEFKDAR---------------AVSQPKSARP---------------------------------- ----------------------------------------------------------------------------TVPI SNATKRSFLVSP------GAADPVLPVQN------------SPEVCNS-------------------------------- -----------------------NKGSSGFSPSHPLLPLRQRQKKAQPAEESTACRNRSNSLT-QEGHPRG-SVAWSD-- ----------------KRQRPLSQLNRYVLHSATDSDADLASGDSVSLTCSISEDSLASTVT---PKHQS---------- ----------------------------------------------HPGQGSVRRINGHSLLGNVN-MDEEEEL------ --------------------------------------------------VAIARADPSKNDITLTNSEDTERQGVTPGA KSIWGRQEDASSDSRTASFFLEPLMPAVLRPAKEKSISLNKEEESGEGRQRGS--------------------------- -------------------------------------------------------------------------------- ----------TRRVAGAESAASSTRRRPPQ-----TLNRTFTPNTSSEFETTIEPKSSEFVP------------------ --PAPGQMQAFRPLVTSSVEPSSAERSPGFYLHSSVTEEKRPVQAWDAH------------------------------- ------------------------PGTSDIETVET----IEEQDAELTKELHPDKKQH------------FEEEVESAKL REDMNVKEHEDK--DGGSR---------------------CSSPGQ--QSQVSSV------------ASGSIRMTSFAER KMQ--RFGSNQDI---------------------------------------------RSSTSSSQRTTPDGS----ESC PLPLTSWRMKRDQSPTP----------------------------------------QNKDNANMLASELVQLHMQLEEK RRAIESQKKKMEILTARQRLKLGKAAFLHIVKKGKS--------------------------------DTLPQPTKSEFY L-------------------KEGQKLNEEKEVSSKDDTCVD-----------------------ALRDRSKEAEEPEKAS CEWAGGGTVSSSPLDV-----------EEEVDLNECNRSIELLNEAIGSIQ--------------------------QQM MQLSLQQEMLMKQNIQSPTSATS-----PLANDQINTSEPRVRA----------------------------SIHFVEPS GSP----VVRKPPKLS-----------SAR-PRSKPSELLLGKEHSK-GQKSSTPTPTDS----PSARSIQGGRTPKAES QDFVQSSVRSESFNKDKGNHKG---------------------------------------------TTFHLNDEANMRM --------------------------------VSRE--PSSVALGVTFEESMS--LRDTETTFDDGTARDNLISSE---- ----------------------------------------DISRGKANLIEVDLSDLAANTDDESTNA-LDVT------- ADGSDGEKKSGMGFFFKDEQKA-EDELAKKRAAFLLKQQR---KAEEARLRKQQLEAE----SEQKRDETRR-------- ---------------------KAEEERIRKEEEKARRELIKQEYLRKKQLELCEEQ------------EQPQPKPKTKP- ------KKQRLKSVVKEEPSIDPLPKCPA--------------ANENLISAQSGSSLSLASVAT---------------- ---TEPDSVNSGGAGSQRGE----SVESFPGLSRNSSRTTERDWDNGSTASSITST------------------------ -------------------------------------------------------------------------------- -------------------------SMAEYT-GPKLFKEPSAKSNKPIIHNAISHCCLAGKVNEPQKNSILEE-LERCES NHLMILFRD-SGCQFRALYSYFPDTEEIHKLTGTGPKSITKKMIDKLYKYSSDRKQFT-VIPAKTVSVSVDALTIHNHLW QA---KRPAGPKKSAK----------- >Takifugu_rubripes_CAMSAP1_a ----------------------------------------RMDVDLSAGGNGSRRKVDIPAVAEATVDIIPLELYDSARA KIAANLRWL-FAKAYGIEN---------------------------IPEDLRDPFYTDQYDQEHIKPPVIHLLLS-SELY CRVCSLILKTEQAASLQS--HMSVIHSLSR------------KGIYVVESDDTPVADEDLSCMP-I------------KM SAHMSMIDALMMAYTVEM-ISIEKVVASVKRFSTFRAS------KELPFDLEDAMVFWIN--KVNMKMREITEREHKVKH HPLES----PSHQK-----------------------------------------------------VRYRRDHASGRQL PFFRVLED---------LMRDICDGAALLTLVHCYCPDLMKLED------------------ICLKEVPSIADSLYNIQL LREFANEY--LN-KSFYLTIEDMLYSPLVLKHNIMVF-----IAELFWWFET-VKPEFVQP------------------- -----------RDLQEFKDSR---------------VVCQPKCTRP---------------------------------- ----------------------------------------------------------------------------AVPI SNATKRSFLANP---DNQNSPEVCNRYFL------------HPEDSDT-------------------------------- -----------------------PRAGPSFSPSHPLLPLRQRQQKQQ--EDGNGMRNRSNSLTGTDGQPRGSVVAWPD-- ----------------KRQRPLSTLSPFMFHSATDGDVDGASGDSVSLARSISKDSLASNILNATPKHLPAAN------- ----------------------------------------------QPPQAAMCRVNG---LHASVHVENEEET------ --------------------------------------------------LAVTRTDAS----LMPKWIDATQPAATVAA K------LSTDPRPAADTFYLEPLMPAALKTAKEKSVCLNKEEESGEGPCSSG--------------------------- -------------------------------------------------------------------------------- ----------WGSLHRGDGSTSAVRRKPPC-----SMNQTYPPP-GEEKDMSVEP------------------------- ----LQSLVDFRPVVTSSIDPSSKESAG-VYLQS-DSEESKSCQVMDTE------------------------------- ------------------------LEDQDEEEED-------LDEAVTTKDPNWTRKAFE-----------DDEEEESAKL QEDMNVKEHEDKDLNGGSG---------------------RSSPCLSTHSQASSM------------ASGSVRMTSFAER KAQQQRFGSNHDL---------------------------------------------YSSATSSQRTTPDGS----ESS GPLN-SWRLKRDQSPSSPMGGWSR-------------------------------TGDGGGSANVLASELVQLHMQLEEK RRAIEHQKKKRDLLMARQRQKLGKAAFLNIVKKDGG------------------------------RSDAFPNPLKADIP K-------------------DE---LGGEKAPPSKELMCAG-----------------------TQK--GDRELEGTFLP GALEADEKENNGNFCP-----------DEELDPYECSRSIEQLNEAINSIQ--------------------------QQM MQVSLKQELLIKQNVQSPPGASP-----TPPLAAEKNGDSKAGA----------------------------SFHFVDHV SGS-STVPTRKPPKLS-----------SSRGSRSKPSELKLGKEQSRVASKALHPAHSGSK-TLPQTRHLEGGRSPKRE- --SPRTPVKEETAERPGDVHT-----------------------------------------------TFRLNDEANIRL --------------------------------PTRVDLTAVAAQEVSFEECLSSTMKESELNSSDGSGRENIPS------ ----------------------------------------EVPRSKAPLIEVDLSELKS-EEDEAV---EDAN------- SEGGEGEQKSVLGFFFKDDRKA-EGDLAKKKAAFLLKQQK---KAEEARLRRQQLEAE----SELKRDEARR-------- ---------------------KAEEDRLRKEEEKMRRELIKQEYQQRKQQEMFEEQKL--------SPKLFKPKTPKPK- ------QRPRPKSVLREESSID-VSKDSS--------------TPDNLSNAQSGSSLSLASAAT---------------- ---NEADSINSGGAGSQRCD----SVESFTG-SVN-SRATERDWDNGSTASSTT-------------------------- -------------------------------------------------------------------------------- -------------------------AKAEYT-GLKLFKEPSAKSNKPIIHNAISHCCLAGKVNEPQKKQILEE-LEKCES NHLMILFRD-SGCQFRALYSYFPDTEEILKLTGTGPKSISKKMIDKLYKYNSDRKQFT-VIPAKTVSVSVDAITIHNHLW QA---KKTSVPKKNGK----------- >Tetraodon_nigroviridis_CAMSAP1_a --------------------------------------------------------------------VVPLELYDSARA KIEANLRWL-LAKDYGIDH---------------------------IPVDLRDPFYTDQYEQEHIKPPIIRLLLS-GELY CRVCGLILHAEQAALLQS--HQAVIQALSR------------KGVYVLQPDNTPVSELDLRSAP-I------------KM SAHVHLIDALMMAYMLEM-ISVEKVVSSVKHFSNLSA-------KELPFDLEDAMLLWIN--KVTMKMREILEKELKMKH HLLES----PSHQK-----------------------------------------------------MRYRREPLSGRTL QHFPLLHD---------LLRDVSDGMALLAVTHFYCPELVKLED------------------ICLKEVPSIADSVYNIQL LKEFSNEY--LN-KCFHLKPEDMLYSPPVLKNNLMVF-----IAELFWWFES-VKPEFVQP------------------- -----------RELQEIRDVR---------------FLLQPQGTRP---------------------------------- ----------------------------------------------------------------------------QVPS --IHKHHFMTSSNSADTLASSISPELRYPPVFSHTFCSKLFFHELEFI-------------------------------- -----------------------GSSKPTSSTSASLLPIQHRYQKLPE-EGMLELRKRSSSVTHADLQPQGSFLARSD-- ----------------RRSRPLSQLPPYALHYGPDDEAD-----AISLARSISKDSLASNMTGITPKHLLRS-------- -----------------------------------------------GPQRSQHRLSGQSLLSHMHIEDQEEEIEEEELV AVIHP-------------------------------------------SSHARSRLASAMEQDELDIPKVTGSSKLPQTY CSPYDDMDRFAAEHPADRYCLEPLMPAVPKAAKEKSISLNKEEESGENHHRAA--------------------------- -------------------------------------------------------------------------------- ----------ATAARKVATSFAATPQRKAA-----GGAQAKVTSSTPPRLVEPGSVRPPVEG------------------ --SVG--QAEKKEPQGFFLHLSGESECRSTFS--LDAGQDSDSDIADLD------------------------------- ------------------------EDDDDEE------------------EEAEEDGELC-----------DAAEGESAKL REDLKVSEREDK--EDASG---------------------QSSPCLSTASWASSCSA---------SASSNIKMTSFAER KLLKLGLRDG------------------------------------------------FSSTSSSQKTTPDGS----E-- VLACPPWQPR---SDC-TSGWMGK-------------------------------EPVLPLSPSVVPSELLQLHMQLEEQ RRAIEYQKKKLETLSARQRLKLGKAAFLNIVK-SGG------------------------------KSDTLPLPLKHSES A--------------------EFADRGEGKTPFCKDDSCLD-----------------------ALK---VQAKTGQTEG GGRGSDNRLSNVNGA--------------EPDRNECSHSIDLLNEAISSIQ--------------------------QQM MQLSLQQDLLMKHVVSPPEQAESGPSATSDATPPAPSTSDPRCF----------------------------AVHFVD-- LGDSS-TPVRRPPKLS-----------SGQ--RRK-TERKQSEDGTKTPTVKS-------------------NAGLSAQK DQKIEDVVESSKMEKSIQRNA-----------------------------------------------TFRVHSDVSTQH --------------------------------GPEQHLDSVSSTPVHQ----PPQQTAQPVGNQAVNSGKEAVGGS---- ----------------------------------------ETTRLKGQLIEVDLSELKDP-EEGSA----EMA------- EPPADSEPKNVLGFFFKDEEKA-EDEMAKRRAAFLLKQQR---KAEESRLRKQQLEAE----SELKRDEARR-------- ---------------------KAEEDRIRKEEEKARRELIKQEYLRRKQQALMEEQ------------GLVKPRPRMKS- ------GRSRPKSLHRGESNSLSRGAATP-----------------DLSGSHRGSTLSLA-------------------- ---TEADSVIS--EESQRAG-SVCSMDSFPVLSRASSRNMERDWDNGSIASSIT-------------------------- -------------------------------------------------------------------------------- --------------------------SVEYNEGPKLFKEPSSKSNKPIIINAIAHCCLAGKVNESQKNAVLEE-LERCES NHLIILFRD-GGCQYRAIYSYSPDTEEMVKFTGTGPRAIGHKMVDKLYKYSSDRKQFT-VIPAKTVSVSIDALTIHNHLW QV---KRPGSARRK------------- >Tetraodon_nigroviridis_CAMSAP1_b ----------------------------------------RMDVDLSAGGNGSRRRVDFPAVAEATVDIIPLELYDSARA KIAANLRWL-FAKAYGIEN---------------------------IPADLRDPFYTDQYDQEHIKPPAIHLLLS-SELY CRVCSLILKTEQAASLQS--HMSVIHSLSR------------KGIYVVESDDTPVADEDLSCMP-I------------KM SSHMSMIDALMMAYTVEM-ISIEKVVASVKRFSTFRAS------KELPFDLEDAMVFWIN--KVNMKMREITEREHKVKH HPLES----PSHQK-----------------------------------------------------VRYRRDHASGRQL PYFRVLEE---------LMRDICDGAALLTVVHCYCPDLMKLED------------------ICLKEVPSIADSLYNIQL LREFANQY--LN-KSFYLTIEDMLYSPLVLKHNVMVF-----IAELFWWFET-VKPEFVQP------------------- -----------RDLQEFKDSR---------------VASQPKSSRP---------------------------------- ----------------------------------------------------------------------------AVPI SNATKRTSLTSP---DNQNSPEVCNRYFL------------HPEDSEP-------------------------------- -----------------------LRAGPSFSPSHPLLPLRQRQQKQQ--EDGNGLRNRSNSLSGTDGQSRGSAVVWPD-- ----------------KRQRPLSTLSPFMFQSATDSDVDRASGDSVSLARSISKDSLASNVLNATPKHLPAAH------- ----------------------------------------------QPPPAATCRVNG---LHS----EGEEGT------ --------------------------------------------------LAAPRSDGS----LMPKWTDRAQPAAAAAA K------LPAEPRPAADTFYLEPLMPATLKTAKEKSVCLNKEEESGEGPCSSG--------------------------- -------------------------------------------------------------------------------- ----------RGSLQRGDGSVSVVRRKPPC-----RTSQTSPP--DEEKDLS---------------------------- ---------EFRPVVTSCVDPSSKGSARVVCPQS-DSEEPKSRQALDAE------------------------------- ------------------------LEDLDEEEDD-------LDEAVTTKESSWSRKAFE-----------EDEEEESAKL QEDMNVKEHEDKDLNGGSG---------------------RSSPCLSTHSQASSI------------ASGSVRMTSFAER KAQQQRFGSNHDL---------------------------------------------YSSASSSQRTTPDGS----ESS GPLS-SWRIKRDQSPSSPLGGWSR-------------------------------TGDGSGSANVLASELVQLHMQLEEK RRAIEHQKKKRDLLMAKQRQKLGKAAFLNIVKKDGG------------------------------RSDAFPNPLKADIP K-------------------EE---LGGEKGPSSKESMCAG-----------------------TEN--GDKELEGTTLP GALEADEKENSGNICT-----------EEELDPYECSRSIEQLNEAINSIQ--------------------------QQM MQVSLKQELLIKQNVQSPPGASP-----TPPSTAEKNGDSKAGA----------------------------SFHYVDHF SGT-STVPTRKPPKLS-----------SSRGSRSKPSELKLGKEQSRLASKALNPPQSGSK-TLPQQRHLEGGRSPKRE- --SPRTPAKEETVERPGEAHT-----------------------------------------------TFRLHDEANIRL --------------------------------PTRVDPTAVAVQEVSFQECLSSTMKESELNSSDGSGKENLPS------ ----------------------------------------ELSRSKAHLIEVDLSELKAPEEDEAA---EDAH------- SEGGEGEQKSVLGFFFKDDRKP-EGDLAKKKAAFLLKQQK---KAEEARLRRQQLEAE----SELKRDEARR-------- ---------------------KAEEDRLRKEEEKMRRELIKQEYQQRKQQEMFEEQ------------NIFKPKTPKPK- ------QRPRPKSVLREETSIESFSKDPS--------------TSDNLSNAQSGSSLSLASAAT---------------- ---NEADSIHSGGAGSQRCD----SVESFTG-SVN-SRATERDWDNGSTASSTT-------------------------- -------------------------------------------------------------------------------- -------------------------ARTEYT-GLKLFKEPSAKSNKPIIHNAISHCCLAGKVNEPQKKQILEE-LEKCES NHLMILFRD-SGCQFRALYSYFPDTEEIIKLTGTGPKSISKKMIDKLYKYNSDRKQFT-VIPAKTVSVSVDAVTIHNHLW QA---KKASVPKKNGK----------- >Gasterosteus_aculeatus_CAMSAP1_a ------------------------------------------------------------------AQVVPLELYDSARA KIEANLRWL-FAKAYGTDH---------------------------IPTDLHNPFYTDQYDQEHIKPPIIRLLLS-GELY CRVCGLILHAEQAASLQS--HQSVIQALSR------------KGLYVLETDDTPVSDLDLSSTP-F------------KM SSHVHLIDALMMAYIVEM-ISIEKVVSSVKRFSNFSAS------KDLPFDLEDAMVFWIN--KVNIKMREIVEKELKMKQ HLLES----PSHQK-----------------------------------------------------VRYRRDHLSGRAL QHFPLLDD---------LLKDVCDGTALLAVIHFYCPELIRLED------------------ICLKDVPSIADSMYNIQL LQEFSHEY--LN-KCFYLKPEDLLYSPRVLKNNIMVF-----IAELFWWFEI-VKPDFVQP------------------- -----------RDLHEIRDVR---------------LLLQPKTSRS---------------------------------- ----------------------------------------------------------------------------HVPI SNVTKRSFLPSSNSADFLTTSPSPDLSMT-----IPCCCIKMHIPRYL-------------------------------- -----------------------NSKPGSLSPSHPLLPLRQRQQK-VA-ESTSVLRNRSNSLTR-DGQHHGSILAWPE-- ----------------RRQRPLSQQLPYALHCPLEDDAD-----SISLARSISKDSLASNILSSTPKHMLG--------- ------------------------------------------------PQLPQHRLSGQSLLSHMRIEDEEEEIEEEELV AVIHP-------------------------------------------SVFSRCRLGSDMEQDELEIPSATSASGVSSSR CSPRLDVGPFPADHPADSYYLEPLMPSIPKPAKEKSISLNKEEESGESRCKGT--------------------------- -------------------------------------------------------------------------------- ----------AAARRAAVNAPSTSQRKAQA-----AGSNRGSFTPIPVAESVTSSTRPPTEG------------------ --SAGMRQSERKQPLGFFLHSSGDADCHAPPCTALDAGHDSDSDIADLE------------------------------- ------------------------EDDEEDDLME-----LTKELARRGKGEFSEEGEVC-----------EFGEGESAKL REDLKVSERDDK--ESGSG---------------------RSSPCLSTASWASSCSA---------TCSTSVKMTSFAER KLLKLGLRDG------------------------------------------------FSSTSSSQKTTPDGS----E-- VTPGSPWQMR---SDS-APGWLGK-------------------------------E-----PISVLASELLQLHMRLEEQ RRAIEYQKKKMEALSARQRLKLGKAAFLNIVKKGGG------------------------------KSDTLPLPLKHSQQ S-------------------LELTDRSKIKTLSCRDDSCLD-----------------------ALK---VQATAGQAEV GQMSRYNKLSQDNVA--------------EPDLNECSHSIDLLNEAISSIQ--------------------------QQM MQLSFQQDLLMNSSPT-------PDTTAESTSS----TSDPRAF----------------------------AVHFVD-- ISGSNVAPARRPPKLS-----------SSQ--RTKASEPRQSKENSKVASIKS------------------CTQSPEGRG E---RSVAESSRPERNLQRNS-----------------------------------------------TFRVRDEPDQRS --------------------------------AGEGTGCASDGALMS------PSRAAEHEENTAADSGQDAVGGD---- ----------------------------------------ENARVKGQLIEVDLSELKDPLADGSL----EVP------- DCTAEGEQKSVIGFFFKDEEKA-EDEMAKRRAAFLLRQQR---KAEEARLRKQHHEVE----SELKRDETRR-------- ---------------------KAEEDRVRKEEEKARREIIKQEYLQRKQEALMEEQ------------GLVKPRPRTKS- ------RRSRPKSLHRAESNSLSKGSTTP-----------------ELSCSHRGSTLSLA-------------------- ---TEADSVISGGAECRRAG-SVCSMESFPTLSRASSRNLERDWENASIASSIT-------------------------- -------------------------------------------------------------------------------- --------------------------STEYN-GPKLFKEPSSKSNKPIIINAIAHCCLAGKVNETQKNVILEE-LEKCES NHLIILFRD-GGCQFRGIYSYSPDTEEIVKFTGTGPRCIGRKMIDKLYKYSSDRKQFN-AIPAKSVSVSVDALTIHNQLW HV---KRPGSARRK------------- >Gasterosteus_aculeatus_CAMSAP1_b ------------------------SGQQEECCPATYVSTTRMEVDLCAGGASTRRKVDLAAAAEGPMDVVPLEMYDSARA KIAANLRWL-FAKAYGIVADH-------------------------IPEDLRDPFYTDQYDQEHIKPPVIHLLLS-CELY CRVCALILKTEQAASLQS--HLSVIQSLSR------------KGIYVVESDDTPVTDEDLACAP-I------------KM SAHMPMIDALMMAYTVEM-ISIEKVVASVKRFSTFSAS------KELPFDLEDAMVFWINKVEVNTKMRELTEREHKVKH HPLES----PSHQK-----------------------------------------------------VRYRREHTSGRQL PFFPLLEN---------LMRDVCDGAALLTVVNYYCPDLMKLED------------------ICLKEVPSIADSLYNIHL LKEFANVY--LN-KSFYLTIEDMLYSPLVLKHNVMVF-----IAELFWWFET-VKPEFVQP------------------- -----------RDLQEFKDAR---------------TVAQPKSARP---------------------------------- ----------------------------------------------------------------------------SVPI SNATKRSFLSSPGSADNLSSPEVCNRYFL------------HPEDSDP-------------------------------- -----------------------LKGGPTFSPSHPLLPLRQRQQKQQG-EDGAGLRNRSNSLTQMDGPPRASVVAWPD-- ----------------KRQRPVSTLNPYMFHSVADSDADVASGDSVSLARSISKDSLASNVV--TPKHQTSVH------- ----------------------------------------------QSAQAATRRLNGHTLLGNVHMEDGEETL------ --------------------------------------------------AAVARADSP----GTPKRVDGTRATATAGP K------PSTESKPAPDSFYLEPLMPSVIKTAKEKSVCLNKQEESGEGPHVSG--------------------------- -------------------------------------------------------------------------------- ----------RGSLRRGDGSTSAVRRKAPC-----GLNQTFPPP-GELFDSSGEP------------------------- ----PNDQGDFCPLVSSSVVPSSREPPEGFYLRL-DSEEPKPAQCLDAE------------------------------- ------------------------LEDLDEEEED-------LDEALTTKDPNWSRKAP------------NDEEEESAKL QEDMNVKEHEDKDLNGGSG---------------------RSSPCLSGHSQAS----------------GSVRMTSFAER KAQQQRFGSNHDL---------------------------------------------RSSASSSQRTTPDGS----ESS GPLASSWRLKRDQSPSSPSGGCIR-------------------------------DGGGGGGSNVLASEIVQLRMQLEEK RRAIEHQKKKMEVLSARQRQKLGKAAFLHIVKKGGGG-----------------------------KSDTLPNPLRADVS R-------------------GE---LGAERAPTSKDDTCVG-----------------------ALR--GDKAATGAASP AALDTEKKEPSGSFHV-----------EEELDLNECSRSIDLLNDAIGSIQ--------------------------QQM MQLSMQQDMLMKQNVQSPSGPAPSGPPAAPPVTADKNGEPKGKA----------------------------GFHFVEHI SGGGSVTPTRKPPRLS-----------SGRGPRSKPSELKIAKEQGRQASRALTPTKSGAE-TLSHLKQSAGGRSPRAEQ PGSPRNPPAGDAVDRPGAGHARS--------------------------------------------ANFRLHDEANIRL --------------------------------PTRVDPKAAVSPDAFFDECLSSSPRGSDLNSSDASGKENVPSD----- ----------------------------------------ELQRSRATLIEVDLSVLKAPEDGEDG---EDS-------- -ADGDGEQKSVMGFFFKDEQKA-EDELAKKRAAFLLKQQK---KAEEARLRKQQLESE----SEQKRDETRR-------- ---------------------KAEEDRLRKEDEKTRRELIKQDYLRRKQQEMLEEQ------------GLVKPKTPKPK- ------QKHRPKSVFREESLGDNFSKSSPP-------------TPDNLSNAQSGSNLSLASAAT---------------- ---NEADSVNSGGGGSQRCD----SVESFPG-SRNNSRTAERDWDNGSTASSIT-------------------------- -------------------------------------------------------------------------------- -------------------------SMAEYT-GPKLFKEPSAKSNKPIIHNAISHCCLAGKVNEPQKNQILEE-LEKCES NHLMILFRD-GGCQFRALYSYFPDTEEIHKLTGTGPRSISKKMIDKLYKYSSDRKQFT-VIPAKTVSVSVDAVTIHNHLW QA---KRGGVPKKSGK----------- >Oryzias_latipes_CAMSAP1_b -------------------------------LTRMDGSAGRDSTRRRRGAAAASPDDGGGDDGATEAQIVHLDLYDSARA KIEANLRWL-FGKAYGTDH---------------------------IPAELRDPFYTDQYEQEHIKPPIIRLLLS-GELY CRVCGSILPAEHAASLRS--HQAVIQTLSK------------RGIHVLETNNTPVSDLDLSSSP-I------------KM SSHIHLIDALMMAYTVEM-FSIEKAVSSVRRFANFSAS------KELPYNLEDAMVFWIN--KVNLKMRELAENECKMKQ HLLDS----PSHQK-----------------------------------------------------VRYRRDHLSGRTL QHFPVLED---------LMKDVCDGTALLTVIHFYCPEVIRLED------------------ICLKEVPSIADCVYNIQL LTEFSNEY--LN-KCFYLTPEDLLFSPPVLKNNLMVF-----IAEVFWWFEI-VKPDFVQP------------------- -----------KNLQEINDVR---------------LLLQPKGSRS---------------------------------- ----------------------------------------------------------------------------FVPV ANVTKRRFLPSSNSADTLTTPPSLDLSS---------------------------------------------------- -----------------------SAKQKSLSPSHSLPPLRRGQQKTVE-EAVSELRNRPNPVTQTDGQHQDSILAWPE-- ----------------RRARPLSQPVSSALCFSAQKDAE-----SVIMARSISKDSLTSNIIP--PKHMLP--------- ------------------------------------------------AGLPKQRLAAQNLLCHIRIEDEEEETEEEELV SVIHP-------------------------------------------SAFSRHRNRSDIEPDDIEEQGKTSSSRVSSS- -TPRQYAAPFMLDQPEDSYYLEPLIAAVPKQAKEKSIRLNKQEESGEMLCRST--------------------------- -------------------------------------------------------------------------------- ----------VSAPKAHVTS--TSQGKPFP-----AKSSRSTCNPT-SEDLAPNSSRLHTEG------------------ --AAGGAETEKK---GFFLHFSGEQDLQGPFSSVIESRQDSDSDVADLE------------------------------- ------------------------EDEEDEDPIE-----LTKEIEIPGGEKVLEVRHSA-----------ECGDGESAKL REDLKVSERDDK--EDLSG---------------------RTSPCLSTVSCASSCSA---------SG---VRMTSFAEK KLLKLSLRDG------------------------------------------------YSSTSNSQKTTPDGS----E-- TAP--AWQGK---EPSPVLGRTMM-------------------------------L-----SPHVVPSELLQLHMQLEEQ RRAIEYQKKKMDTVSARQRLKLGKAAFLNIVKKGGG------------------------------RSDTLPLPLKHSQG SP-----------------GLGVADRRTPKTLSCKDDSCLD-----------------------AFK---VQTGASADKN NRLT----LSQDNSS--------------EPDLNDCSRSIDLLNEAISSIQ--------------------------QQM MQLTLQQGLLMKQSAVSPSEPVQPEPCTASTTMPEPLTSDSKSF----------------------------AVNFVD-- IGGSSSTPVRRPPSLS-----------SSK--RRRPSEQKPGKESSKTPSVDSSSS------------SLDCTPSPRECS EEEQRALLESSKMERSIQRNV-----------------------------------------------TFRVHEGTGERS --------------------------------GQYSSQTKLQDPLVSSKTSESPLVDVEEEEINTADSGNEIVSGD---- ----------------------------------------ESSRTKGLLIEVDLSELKAPQEECIV----DGP------- DSTAEGEQKNVLGFFFKDEEKA-EDEMAKRRAAFLLKQQR---KAEEARLRKQQQEAE----AELKREEARR-------- ---------------------KAEEERIRKEEEKARRELIKQEYLRRKQEALMEEQ------------GLVKPHVRTKS- ------RRNRPKSLHREESSSFSKGSTTP-----------------DLSLSHRGSTLSLA-------------------- ---TEADSVISGEAETYRAE-SVCSTESFPMLSRASSRNMERDWENGSITSSIT-------------------------- -------------------------------------------------------------------------------- --------------------------SSEYN-GPKLFKEPSSKSNKPIIINAIAHCCLAGKVNEVQKNLVLEE-LEKCEC NHLIILFRD-GGCQFRAIYTYSPETEEITKFTGTGPRSISHKMIDKLYKYSSDRKQFT-IIPAKSVSASVDALTIHNHLW QI---KRPGSARRKCIPQ--------- >Branchiostoma_floridae_CAMSAP1 ------------------------------------------------MSEELQTRQTDTVDGPTVPDIVPLTEYDPFRA KVHASMLWA-IGKAYGG---M-------------------------VPPELQWPFFTDDEGTEQLTPLLVGMLTA-GELY CMICTQMFR--EPCDWGG--HWSVIQALSR------------RGIQAMEDEENGVSQENLQEAQPI------------NL KSHLAVLDALMEAYINEV-ISIEGVVTAVKKFATFNAS------QELPYDMEDALLFWLN--KV