>Homo_sapiens_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MDRGTLPLAVALLLASCSLSPTS-LAETVHCDLQPVGPERG-EVTYTTSQVSKGC VAQA----------------------------------PNAILEVHVLFLEFPTGPS---------QLELTLQASK---- -----------------------QNGTWPREVLLVLSVNSSVFLHLQALGIPL------------------------HLA YNSSLVTFQEPPGVNTTELPSFP----KTQILEWAA-ERGPITSAAELNDPQSILLRLGQ-------------------- ---AQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGP----RTVTVKVELSCAPGDL D----AVLILQGPPYVSWLIDA---------NHNMQIWTT---GEYSFKIFPEKNI--RGFKLPDTPQGL------LGEA RM-----------------------------LNASIVASFVELPLASIVSLHA-SSCGGR-----------------LQT SPAPIQTTPP-KDTCSPELLMSLIQT------------------------------------------------------ ----------------------------------------------KCADDAMTLVLKKELVAH-------LKCTITGLT FWDPSCEAEDR---------GDK-FVLRSAYSSCGMQVSASMISN------EAVVNILSSSSPQRKKVHCLNMDSLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IEPGQQSFVQVRVSPSVSEFLLQLDSCHLD--LGPEGG-TVELIQGRAAKGNCVSLLSPSPEGDP------------ ---------------------------------------------------------------------RFSFLLHFYTV PIPKTGTLSCTVALRPKTGSQD----------------------------------QEVHRTVFMRLNIISPDLSGCT-- ------------------SKGL------------VLPAVLGITFGAFLIGALLTAALWYIYSHTRS-------------- -------------------------------------------------PSKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Pan_troglodytes_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------LAETVHCDLQPVGPERG-EVTYTTSQVSKGC VAQA----------------------------------PNAILEVHVLFLEFPTGPS---------QLELTLQASK---- -----------------------QNGTRPREVLLVLSVNSSVFLHLQALGIPL------------------------HLA YNSSLVTFQEPPGVNTTELPSFP----KTQILEWAA-ERGPITSAAELNDPQSILLRLGQ-------------------- ---AQGSLSFCMLEASQDMGHTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAG--------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------R-----------------LQT SPAPIQTTPP-KDTCSPELLMSLIQT------------------------------------------------------ ----------------------------------------------KCADDAMTLVLKKELVAH-------LKCTITGLT FWDPSCEAEDR---------GDK-FVLRSAYSSCGMQVSASMISN------EAVVNILSSSSPQRKKVHCLNMDSLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IEPGQQSFVQVRVSPSISEFLLQLDSCHLD--LGPEGG-TVELIQGRAAKGNCVSLLSPSPEGDP------------ ---------------------------------------------------------------------RFSFLLHFYTV PIPKTGTLSCTVALRPKTGSQD----------------------------------QEVHRTVFMRLNIITPDLSGCT-- ------------------SKGL------------VLPAVLGITFGAFLIGALLTAALWYIYSHTRS-------------- -------------------------------------------------PSKREPVVAVAAPASSESSSTHH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Macaca_mulatta_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------TTGEYS--- ------------------------------------------------FKIFP---------------EKNIRGFK---- -----------------------LPDT-P-----------------QGLLGEA------------------------RML NASVVASFVELP-----------------------------LASVVSLHAP----------------------------- --------------------------------------------------------SCG--------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------GR-----------------LQT SPAPIQTTPP-KDTCSPELLMSLIQT------------------------------------------------------ ----------------------------------------------KCANDAMTLVLKKELVAH-------LKCTIMGLT LWDPSCQAEDR---------GDQ-FVLHSAYSSCGMEVTANMISN------EVVVNILSSSSPQRKKVHCLNMDSLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IEPGQQSFVQVGVSPSIPEFLLQLDSCHLD--LGPEGG-TMELIQGRAAKGNCVSLLSPSPEGNP------------ ---------------------------------------------------------------------RFSFLLHFYTV PIPKTGTLSCTIALRPKTGSQD----------------------------------QEVRRTVFTRLNVISPDLSGCT-- ------------------SKGL------------VLPAVLGITFGAFLIGALLTAALWYIYSHTRS-------------- -------------------------------------------------PGKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Mus_musculus_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MDRGVLPLPITLLFVIYSFVPTTGLAERVGCDLQPVDPTRG-EVTFTTSQVSEGC VAQA----------------------------------ANAVREVHVLFLDFPGMLS---------HLELTLQASK---- -----------------------QNGTETQEVFLVLVSNKNVFVKFQAPEIPL------------------------HLA YDSSLVIFQGQPRVNITVLPSLTS---RKQILDWAA-TKGAITSIAALDDPQSIVLQLGQ-------------------- ---DPKAPFLCLPEAHKDMGATLEWQPRAQTPVQSCRLEGVSGHKEAYILRILPGSEAGP----RTVTVMMELSCTSG-- D----AILILHGPPYVSWFIDI---------NHSMQILTT---GEYSVKIFPGSKV--KGVELPDTPQGL------IAEA RK-----------------------------LNASIVTSFVELPLVSNVSLRASSCGGV------------------FQT TPAPVVTTPP-KDTCSPVLLMSLIQP------------------------------------------------------ ----------------------------------------------KCGNQVMTLALNKKHVQT-------LQCTITGLT FWDSSCQAEDT---------DDH-LVLSSAYSSCGMKVTAHVVSN------EVIISFPSGSPPLRKKVQCIDMDSLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IELGQQAFVQVSVSPLTSEVTVQLDSCHLD--LGPEGD-MVELIQSRTAKGSCVTLLSPSPEGDP------------ ---------------------------------------------------------------------RFSFLLRVYMV PTPTAGTLSCNLALRPSTLS------------------------------------QEVYKTVSMRLNIVSPDLS----- ------------------GKGL------------VLPSVLGITFGAFLIGALLTAALWYIYSHTRG-------------- -------------------------------------------------PSKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Rattus_norvegicus_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MDRSMLPLVITLLLVIYSFVPTS-LAERVGCDLQRVDSTRG-EVTYTTSQVSEGC VAQV----------------------------------ANAAHEVHVLFLNLSRRKS---------ELELTLHASK---- -----------------------QNGTETAGGFSVFISNENVLVKLQAPEIPL------------------------HLV YHSSLEVFKG-PKVNSTPLPSFTS---KTQILDWAA-TKGTITSIAALDDPKSIVLRLGQ-------------------- ---DPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGP----RTVTVTVKLSCTSG-- D----AVLILQGPPYVSWLIDT---------NHNMQIWTT---GEYSIKIFPENNI--KGFELPDTPQGL------IGEA RK-----------------------------LNASIVT-FVEIPLTSDVSLTVSSCGGG------------------LQT SPAPVVTTPP-KDTCSPELLMSLIQP------------------------------------------------------ ----------------------------------------------KCGNDVMTLALNKKLVQT-------LQCTITGLA FWDSSCQAKDQ---------DGH-LVLSSTYSSCGMKVTDHVISN------EVIINLPSGLPPLRKKVQCIDMDSLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IELGQQGFVQVSMSPLTSEVTVQLDSCHLD--LGPEGD-MVELIQSRAAKGSCVSLLSPSPEGDP------------ ---------------------------------------------------------------------RFSFLLRVYMV PTPAAGTLSCNLALHPSTLS------------------------------------QEVYKTVSMRLNIVSPDLS----- ------------------GKGL------------VLPSVLGITFGAFLIGALLTAALWYIYSHTREYPKPLHPLPTVSAQ GRSTPPQGTPWEASEEVGSPGWGPD--------------LHPCPHLSGAPSKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Canis_familiaris_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MDRTALPLVVALLLAICSLRHTG-LAETIHCDLQPVDA----EVTYITSQVSEGC VAQV----------------------------------PNATVEVHILFLESSRELS---------ELELTIQKSK---- -----------------------QNGTRPREVFLVLSAKKNVLLQLQAPGIPL------------------------YLA FNPK-LIFQGHPGVNTTELPSFTT---KSQLLAWAD-TKGSIASIAELNDPQSILLRLD--------------------- --QAPKSPSFCNLEPLVDMGHTLEWSPLTRASVRGCRLEGVPGHKEAHIVRVLPGPEAGP----RTVTVKVELRCASGDP E----AVLILQGPSHVSWLIDA---------NHNMQIWTT---GEYSFKIFPEKNI--RGFVLPDTPQGL------LGEA RR-----------------------------LNASMVASFVELPLASVVSLQAHSCGGGG-----------------LQT SPPPVQTTPPPTESCNQELLLSLIQP------------------------------------------------------ ----------------------------------------------KCSEDVMTVVLKKDLIST-------LRCTIMSLT FSDPSCQAEDR---------DDQ-FVLRSTYSSCGMAVTENVVSN------EVVVNLFPSSSLQWKKVHCINMESLS--- -----------------------------------------------------------FQLGLYLSPHFLQASNT---- ---IELGQQGFVQVSMTPSIPELTLQLDSCQLD--LGPEGD-TVELIQSQTAKGSCVSLLSPGPGGDV------------ ---------------------------------------------------------------------RFSFLLRGYMV PTPTTGTLTCTVALRSRSLSPK----------------------------------METHRTISMRLNIVSPGLPACL-- ------------------DKGL------------VLPAVLGITFGAFLIGALLTAALWYIYSHTRP-------------- -------------------------------------------------PGKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Equus_caballus_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MDRGALPQVVALLLAVCSLSPTS-LAETIRCDLQPADP----KVTYATSQVSEGC VAQV----------------------------------PNTNLEVHILFLEFPRDVS---------ELKLTIQRSK---- -----------------------QNGTGPREALLVLSTNKTAFVRLEAPGIPL------------------------RLA YDPQLIIFQETPRVNTTGLPPFTS---KRHLFKWAN-TNGSIASAAELKDPESILLRLD--------------------- --QAQTAPSSCSLEPHVDMGHTLEWQPRAGASVRGCRLEGVAGHKEAHILRVLPGRDTGR----RTVTVKVELSCASGDP D----AVLILQGPPYVSWLIDA---------NHNIQFWAT---GEYTLKIFPERNI--PGYMLPDTLEGL------LEEA QR-----------------------------LNASVVASYVELPLASDVSLQAHSCGGG------------------LQT SPMPVQTTPP--KSCNQELLMSLIQP------------------------------------------------------ ----------------------------------------------TCSDDVMTLVLKKELISS-------LHCTVMSLT FWDSSCQADDR---------DDH-LVLRSTYSNCGMKVTENVVSN------EVVVNLLSSSSPQRKKVHCVNTESLS--- -----------------------------------------------------------LRLGLYLSPHFAQASNT---- ---IELGQQGFVQVSVSPMIPEHVFQLESCHLD--LGPDTD-TVELIQSHTAKGSCVSMLSPSPEGDM------------ ---------------------------------------------------------------------RFSFLLRGYMV PTPKTGTLSCTIALYPRIWS------------------------------------QEVQKTVSMRLSIVSPGMP----- ------------------GKTL------------VLPAVLGITFGAFLIGALLTAALWYIYLHTRP-------------- -------------------------------------------------PSKREPVVAVAAPASSESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Monodelphis_domestica_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------MVGVFYFAMFLAAWDFSLAS-PLEKDVCDLELPDSETG-KVTYTPEQVSWGC LGQRN---------------------------------HNSTQEVHILNLRFPKDIS---------VLELTIQAHE---- -----------------------GNEPQIRHVQVILIVQGLINLLLQAPRIPV------------------------NFS LDPD-RVFFGATDVNYTPLPDFFT---REELLDWAQRTHGNITSYAEMDNPQSITLHLGQ-------------------- ---ALPYAFPCIPELNFNMGSHLTWKTLALG-VRGCRFRKGLGKKVAHVLKITQGPSSSP----QTVEVKMNLSCPLGNL NPTLETVLILQGPRNINWLIDS---------HNNVQIETT---GEYSFKIFPNNRIS--GSIGSDTLQEL------LDEV QKK----------------------------YNASTIASYVEIPATSHISLWAPSCAST------------------VET SPSPVLTTPF-MMTCYFPLLSSLLLP------------------------------------------------------ ----------------------------------------------QCSPDSMTLVLKKEFIAV-------LNCQIKHLS FRDPSCQSQEI---------DNQ-FVLSSTFSGCGMNLKKGVILNN-----EVTVTLTSRSEPVLIEVECLNTSAFS--- -----------------------------------------------------------VQMEAYHSQQFLRTSNT---- ---IELGQRVYVQVTVAPAIEELIAQLDSCSLD--LGPEAD-PVELIHDQVPKSPRVSFLMS-DSSRI------------ ---------------------------------------------------------------------QFSFLLRGHMV PTPTAATLSCNVELVLKARK-E----------------------------------TKTTIKTSMKLNISNPIPT----- -------------------QGL------------GMPAVLGITFGAFIIGALLTAALWYIYSHTRP-------------- -------------------------------------------------PGKRQPVMATVP--ASESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Gallus_gallus_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------MCRRSSPLLPLLLALLGRPDPAP----AEHCDLQPVTAEPPITLFYTTSTVLRGC VSNSS---------------------------------TLASHEVHVLSIQWSKTPV---------P-MLNVSITP---- -----------------------RDDDCTRPAALILQCTQCLASITLPCQN----------------------------- LLIHTDASLRPKVQGKELPKDAK-----GHLLEWVQRTYGGITSYSELKDPQRIHLQLGE-------------------- ---NSNSPQNCIPQKDFDATPHLEAEVLFRE-VKGCTSSSAQSARAAHIVQLLHKPSLP------ITEVKLTLNCPRQ-- -QQNNQILLLQGPANLTWLLMLN--------NCSLQFLAS---GTYKILHFPMDPRK--GELLPDTEQGL------IAKA FE-----------------------------KNYSIIASYSVIPISPHITLNIHEREVPK-----------------KLP VGPTSSAPSP--DDVSSSLLFTLS-------------------------------------------------------- --------------------------------------------PWKCTDDTMEIVIARSNLEP--------IKDVVNIT LRDISCQAEKN---------ATH-FMLHTLLSHCGTSLENHGHANN-----ELVLSLSKGSVLRSVRVAFQCPIPRE--- -----------------------------------------------------------LFLRLFPTAAFKAPQTE---- ---LEVNKEVFVQASMHLEDYPADLQLKECYLM--APGMEP--LLLVQGNKAQSSSVAMLEEPPSNRA------------ ---------------------------------------------------------------------RKVWRFRFTYT VPEGRHVPFSATLKCKAGLQNN----------------------------------TIFEKVLEVKVKDVWRLPN----- ------------------NQGL------------GLSAVLGITFGAFLIGALLTAGLWYIYSHTRP-------------- -------------------------------------------------ISKLQPVSTTAP--ASESSSTNH-------- ------------------SIGSTQSTPCSTSSMA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Anolis_carolinensis_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------TGPTQAADRRSSPLLGPVDLSTCDLEPLTAKDGVNVFYTTSRAARGC RGRGP---------------------------------TDPGLDVHVLFLRYSAQQE---------SAVLSVDAQV---- -----------------------LSRNFPCNVLLCQLSALVCSAVFFIIIIIIG-------------------LSPLILS FFPQATANVMLQRPGVETPQANLTSSSSEELLTWAKAAYGGVSSFAELEDPLKIHFRLGQ-------------------- ---DPGSSVDCVPEKRFSTEPYLEVEAAFAN-IQGCPSSGQNTEKEAHVLWLQEDALGAS----HEVDLDIQLKCKEGEP ENLLPILLVLKSHRGLTWHIGP--------VFSSFKFMVS---SNYYLKNFGASRLP--GEDLPDSKEGL------IAAA RS-----------------------------KEFAFVASYMEIPSATSITLELDRLCE---------------------- KPPTPATEPPQETGLTLTEFMRVNITHWKP-------------------------------------------------- ---------------------------------------------WRCLDSGVQIALAKDYLHGLLL----NAIKVTDVS LQDRSCRAVDN---------GTH-FVLKSQLRECGTSLERDVVVRNQ--DAIAVSTILLSISLLRMLVKCYNWRSSP--- -----------------------------------------------------------IILQLYGAPDYESGPPTS--- --VIEVNQAAYVLARFRTSDPLALLEIKDCSLEMPNEASSRLLISGDNALSANTKALDSFSSTVR--------------- ---------------------------------------------------------------------RFSFAFKTGQE S---WGASPATIVCRVQLYSQH----------------------------------QNPGRVEPMTIHSLAPSLN----- --------------------GLVASSL-------GVGTLLGITFGAFLIGVLLTAALWYIYMQTR--------------- ---------------------------------------------------EYRPNRAHLGPRLWGSSPNLG-------- ------------------------LFPRA--------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Branchiostoma_floridae_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------MPREIIVPTVASMSVRRGAVMLMPPVTVTNVLVLVALLGVTVELVSGLSCIPKRNFRSPYVTPLYQQLTVSSGC ESRAT---------------------------------VGFDHEVYVVNLLSGSPAYLSVASTEVALHISARMNRI---- -----------------------LPGLTEKPLMFVLNSHQPIVWKIKVNGLAPNRQAFFHFVNGNGTLLNVFLLFSYLLV LVTLGSSVTVEGEMIVAVNTEGSMPLQGEALLAWTRRMYHGITSFTELEHANDIYIKVGE-------------------- ---DMLSPPRCNITRNFLSPNSYSAYLQPQPAHGCIAMTTANQEQEVHVVEIHSANKNPFA--KILSSIVVDIQPRDKEK MEQNIVLVLKSHTKGVKWRIMSQN------IKGSLHVLAN------ALVDVSEAGMGPVTSQMAEISANG----EDLIRW VEQD---------------------------KGYHRIQSYTEVQLTNRLQIKLGIPEASR----------------MIDQ GMLAGRTLDGSVPVSRPPLPMSQEELES---------------------------------------------------- --------------------------------------ALHAAMSVRCRERAMEVALAKAVLQP-------YGITEVQLS LQDADCTAGAN----------ITHFILSTTLEGCATSRHMHTKSATFFNTVVLSGMVEIQQEGSGDAGSADGPDAGDMEL EVPSVIANFECDYPSVSLAEERIDGSILEAVPTAAS------------------DDPVSFHMEIYKTSLYMRPEVEF--- PMVKETDERIFVDIQVAT-DEGLALKVDHCYMSDSSLKDSPPLYNLIEDGCPVTSNSVQYLAVTPMDTDSLSTQ------ ------------------------------------------------------------------KKQRFSFLPKN-TV MPFVFLHCQLTVCSEGDIFIPEIEQCVDL-----------NDFCLRKRDSEQHRVPKSSVYSQHRFVGPFIVSGSSGTEE PDHKGKAEESKVKSRQEGPQIVIQG-L-------EAGTVVGIAFAAFVIGIVLTATLWYIHTHTGP-------------- ------------------------------------------------KRQKSDNNSSPVPPRHQVPPAQLPHRLP---- ----------TYDCNGYHTQNHRKPEPGSTSV------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Strongylocentrotus_purpuratus_ENG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------LYHLFFFT--------------VN VGNTACLEGNT----------------AQPISGLGAG------------------------------------------- -------------------------------------------------------------------------------- -----------PAAAIAFAAFTIGVLLTACL------------------------------------------------- ------------------------------------------------------------------------WFIHAHTG PRRQGPGSPRTLSSPSSPMVNG---------------------------------------------------------- ----------------------------------------HIPNGHLPNGGHMVARQRPPPVP----------------- --------------------------------------------------APNGPLHIPLANGINPNMIPAR-------- ---------------------GLMNGPVGESV------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Homo_sapiens_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MTSHY------------VIAIF-ALMSSCL------ATAGPEPGALCELSPVSASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRT-AGQGPGQLQR---EVTLHLNPIS---- -----------------------SVHIHHKSVVFLLNSPHPLVWHLKTERLATG-------------------VSRLFLV SEGSVVQFSSANFSLTAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGE-------------------- ---DQVFPPKCNIGKNFLSLNYLAEYLQPKA-AEGCVMSSQPQNEEVHIIELITPNSNPYS--AFQVDITIDIRPSQEDL EVVKNLILILKCKKSVNWVIKSFD------VKGSLKIIAP---NSIGFGKESERSMTMTKSIRDDIPSTQ----GNLVKW ALD----------------------------NGYSPITSYTMAPVANRFHLRLENNA--------------------EEM GDEEVHTIPPELRILLDPGALPALQNPPIRGG-EGQNGGLPFPFPDISRRV-WNEEGEDGLPRPKDPVI----------- -------------------PSIQLFPGLREPEEVQGS--VDIALSVKCDNEKMIVAVEKDSFQA-------SGYSGMDVT LLDPTCKAKMN---------GTH-FVLESPLNGCGTRPRWSALDGVVYYN-SIVIQVPALGDSSGWPDGYEDLESGD-NG FPGDMDE-GDA--SLFTRPEIVVFNCSLQQVRNP------SSFQ-------EQPHGNITFNMELYNTDLFLVPS-QG--- VFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQADM------ ------------------------------------------------------------------DKKRFSFVFKPVFN TSLLFLQCELTLCTKMEKHPQK-LPKCVP-----------PDEACTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKE-- KGPSMKEPNPISPPI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Pongo_abelii_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MRHSVGEIKMTSHY------------VIAIF-ALMSSCL------ATAGPEPGALCELSPVSASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRT-ADQGPGQLQR---EVTLHLNPIS---- -----------------------SVHIHHKPVVFLLNSPHPLVWHLKTERLATG-------------------VSRLFLV SKGSVVQFSSANFSLTAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGE-------------------- ---DQVFPPKCNIGKNFLSLNYLAEYLQPKA-AEGCVMSSEPQNEEVHIIELITPNSNPYS--AFQVDITIDIRPSQEDL EVVKNLILILKCKKSVNWVIKSFD------VKGSLKIIAP---NSIGFGKESERSMTMTKSIRDDIPSTQ----GNLVKW ALN----------------------------NGYSPITSYTMAPVANRFHLRLENN---------------------EEM GDEEVHTIPPELRILLDPGALPALQNPPIRGG-EGQNGGLPFPFPDISRRV-WNEEGEDGLPRPKDPVI----------- -------------------PSIQLFPGLREPEEVQGS--VDIALSVKCDNEKMIVAVEKDSFQA-------SGYSGMDIT LLDPTCKAKMN---------GTH-FVLESPLNGCGTRPRWSALDGVVYYN-SIVIQVPALGDSSGWPDGYEDLESGD-NG FPGDMDE-GDA--SLFTRPEIVVFNCSLQQVRNP------SSFQ-------EQPHGNITFNMELYNTDLFLVPS-QG--- VFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPVPQADM------ ------------------------------------------------------------------DKKRFSFVFKPVFN TSLLFLQCELTLCTKMEKHPQK-LPKCVP-----------PDEACTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKE-- KGPSMKEPNPISPPI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Macaca_mulatta_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MRHTVGEIKMTSHY------------VIAIF-ALMSSCL------ATAGPEPGALCELSPVSASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRT-ADQGPGQLQR---EVTLHLNPIS---- -----------------------SVHIHHKPVVFLLNSPHPLVWHLKTERLATG-------------------VSRLFLV PEGSVVQFSSGNFSLTAETKKRNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGE-------------------- ---DQVFPPKCNIGKNFLSLNYLAEYLQPKA-AEGCVMSSQPQNEEVHIIELITPNSNPYS--AFQVDITIDIRPSQENL EVVKNLILILKCKKSVNWVIKSFD------VKGSLKIIAP---NSIGFGKESERSMTMTKSIRDDIPSTQ----GNLMKW ALD----------------------------NGYSPITSYTMAPVANRFHLRLENNA--------------------EEM GDEEVHTIPPELRILLDPGALPALQNQPIQGG-GGQNGGLPFPFPDISRRV-WNEEGEDGLPRPKDPVI----------- -------------------PSIQLFPGLREPEEVQGS--VDIALSVKCDNEKMIVAVEKDAFQA-------SGYSGMDVT LLDPTCKAKMN---------GTH-FVLESPLNGCGTRPRWSALDGVVYYN-SIVIQVPALGDSSGWPDGYEDLESGD-NG FPGDVDE-GDA--SLFTRPEIVVFNCSLQQVRNP------SSFQ-------EQPHGNITFNMELYNTDLFLVPS-QG--- VFSVAENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKDESVKFYSPRRVHFPIPQADM------ ------------------------------------------------------------------DKKRFSFVFKPVFN TSLLFLQCELTLCTKTEKHPQK-LPKCVP-----------PDEACTSLDASIIWAMMQNKKTFTKPLAVIHHEVESKE-- KRPSVKEPNPISPPI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Mus_musculus_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------MAVTSHH------------MVPVF-VLMSACL------ATAGPEPSTRCELSPISASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPREVHILNLRS-TDQGLGQPQR---EVTLHLNPIA---- -----------------------SVHTHHKPVVFLLNSPQPLVWHVKTERLAAG-------------------VPRLFLV SEGSVVQFSSGNFSLTAETEERSFPQENEHLLHWAQKEYGAVTSFTELKIARNIYIKVGE-------------------- ---DQVFPPTCNIGKNFLSLNYLAEYLQPKA-AEGCVLASQPHEKEVHIIELISPNSNPYS--TFQVDIIIDIRPAREDP EVVKNLVLILKCKKSVNWVIKSFD------VKGNLKVIAP---DSIGFGKESERSMTVTKLVRNDIPSTQ----ENLMKW ALD----------------------------NGYSPVTSYTIAPVANRFHLRLENN---------------------EEM RDEEVHTIPPELRILLGPDHLPALDSPSFQGE--IPNGGFPFPFPDIPRRG-WKE-GEDRIPRPKEPII----------- -------------------PRVQLLPDHREPEEVQGG--VNIALSVKCDNEKMVVAVDKDSFQT-------NGYSGMELT LLDPSCKAKMN---------GTH-FVLESPLNGCGTRHRRSAPDGVVYYN-SIVVQAPSPGDSSGWPDGYEDLESGD-NG FPGDTDE-GET--APLSRAGVVVFNCSLRQLRSP------SGFQ-------DQLDGNATFNMELYNTDLFLVPS-PG--- VFSVAENEHVYVEVSVTKADQDLGFAIQTCFISPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEV------ ------------------------------------------------------------------DKKRFSFVFKSVFN TSLLFLHCELTLCSRK-KGSQK-LPKCVT-----------PDDACTSLDATMIWTMMQNKKTFTKPLAVVL-QVDYKE-- NVPNMKESSPVPPPP-QIFHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETARRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Felis_catus_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---SSRLINLTVAQ------------LIAVS-EGFVFMI------LSADPEPGTQCEVSPVNASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRA-ADPGPDQPQR---EVTLHLNPIS---- -----------------------SVHIHHKPIVFVLNSPQPLVWHLKTERLAVG-------------------VSRLFLV SQGSMVQFSSGNFSLSAKTEEKRFPYRNDRLLSWARKEYGAVTSFTELKIARNIYVKVGE-------------------- ---DQVFPPTCNIGKNFLSLNYLAEYLQPKA-AEGCVISSQPQDKEVHIIELITPSSNPYSHSAFQVDIIIDIRPSRKDL EVVKNLILILKCKKSVNWVIKSFD------VKGNLRVVAP---NSIGFGKESERSMITTKSVRDDIPSTQ----ENLFKW ASD----------------------------NGYSPVTSYTVAPVANRFHLRLENSAP-------------------EEM RDEEVHTIPPELRILLDPGSLPALENPPIRGG-GGRNGGFPFPIPDISRRG-QVERGEDGIPQPRDPIV----------- -------------------PSLRLFPGPEEPKEVQEN--VDISLSVKCDSEKMVVSVEKESFQA-------NNYSGMELT LLDPTCKAKMN---------GTH-FILESPLSGCGTWHRRSAPDGVIYYN-SIVMQVPSPGDSSGWLDGYEDLESGD-HG FPGDVDE-GDT--SFFSRPEIVVFNCSLRRVRNH------SGFQ-------DPLHRNVTFNMELYNTDLFLVPS-QG--- VFSVAENGHIYVEVSVTKADQELGFAIQTCFISPYSNPDRMSDYTIIENICPKDESVKFYNPKRVHFPIPQAEM------ ------------------------------------------------------------------DKKRFSFVFKSIFN TSLLFLQCELTLCTKKEKDPQK-LPKCVP-----------PDEACTSLDASMIWAMMQTKKTFTKPLAVIHQQEEVKE-- TSLSIKEPNPVPPQI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSHTV--------------- -----------------------------------------------TAGQTAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSAA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Equus_caballus_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------I------ASAGPEPSTQCELSPVNASHPVQALMESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRA-ADPGPGQPQR---EVTLHLNPIS---- -----------------------SVHIHHKPVVFLLNSPQPLVWHLKTERLAIG-------------------VSRLFLV SEGSVVHFSSGNFSLSAETEERSFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGE-------------------- ---DQVFPPTCNIGKNFLSLNYLAEYLQPKA-AEGCVISSQPQDKEVHIIELITPNSNPY--SAFQVDIVIDIRPSRKDP EVVKNLILILKCKKSVNWVIKSFD------VKGNLKVIAP---NSIGFGKESERSMIMTKSIRDDIPSTQ----ENLVKW ALD----------------------------NGYSPVTSYTVAPVANRFHLRLENN---------------------EEM RDEEIHTIPPELRILLDPGILPAL-NPPIRGG-GGRNGGFPFPFPDISRRG-QKEGGEDGIPRPKDPVI----------- -------------------PSIRLFPGPREPEEVQGS--MDVALSVKCDNEKMTVAVEKDSFQA-------NSYSGMELT LLDPTCKAKMN---------GTH-FILESPLNGCGTRHRRSAPDGVVYYN-SIVIQVPSLGDSSGWPDGYEDLESGD-NG FPGDTDE-GET--SFFSRPEIVVFNCSLRQVGKP------SSFQ-------DPPNRNITFNMELYNTDLFLVPS-QG--- IFSVAENGHIYVEVSVTKADQELGFAIQTCFISPYSNSEGMSDYTIIENICPKDESVKFYNPKRVHFPIPQAEM------ ------------------------------------------------------------------DKKRFSFVFKSVFN SSLLFLQCELTLCTKKEKDPQK-LPKCVP-----------PDEACTSLDASMIWAMMQNKKTFTKPLAVIHHQVESKE-- TGPSIKEPSPISPPI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Dasypus_novemcinctus_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------LYHKVLSKFKGNPASLIVLLSPERTRLG-------------------IDFSCLV SEGSMVQFSSGNFSLSAKTEERHFPRGNKHLLNWAQKEYGAVTSFTEFKMARNIFIKVGE-------------------- ---DQVFPPTCHIRKNFLSLNYLAEYLQPKA-AEGCVMSSQPQNQEVHIIELLTSNSNSYSHSAFQVDIVIDIRP-RKDP EVVKNLILILKCKNSVNWVIKSFD------IKGNLRVLAP---NSIGFGKETERSMTITKSIKDDIPSTQ----ENLVKW AVD----------------------------NGYSPVTSYTMAPVANRFHLRLANN---------------------ELM RDEEVHTTPPELRILLGTDTLHTLKNPPLQGE-GGRDRALPFPFPDISKRD-RKEAGERGLPQPKGASI----------- -------------------PSILLFPGPREPEEVQGS--KDVVLSVKCSNEKMIVAVEKDSLQA-------SSYSRLELT LLDPSCKAKLN---------GTH-FILESPLNGCGTQHRLLAPNGMIYYN-SIVIQVPSPGDSSGWPDGYEDLESGD-NG FLGDMEE-RDV--SFFSRPEIVMFNCSLWQVENP------SVSQ-------DPPNSNITFNMELYNTDLFLVPS-QG--- VFSVAENEYIYVEVSLTKADPELGFAIQTCFISPYSNSDRMSDYTIIENICPTDESVKFYSPKRVHFPLPQAEK------ ------------------------------------------------------------------DKKRFSFAFKPIFS TSLLFLHCELTLCTRAEESSLK-LPKCVP-----------PDEACTLLDASMIWAMMLNKKTLTKPLAVIHHEIESKG-- TGPSPKESNPIPPPI---FHGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETTRRQQVPTTPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSPA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Monodelphis_domestica_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MASQW------------MVTML-ALISWCL------ATAGPVPRTECVLSPVNSSHPVQALLESFTVLSGC ASRGT---------------------------------TSLPQEVHILNLRN-PDESPGQPRR---EITLHLKPIS---- -----------------------SVHIHQKSVVFLLNSPQPLVWKLKTERLAPG-------------------VPRLFFV SEGSTVQFPEGNFSLSTKTEERSFPHGNVHLLHWAQNEYGAVTSFTELKISRNVYIKVGE-------------------- ---DQVFPPTCNIEKNFLSLNYLAEYLQPKM-AEGCIMSSLPHGQEVHIIELITPNSNPYS--AFQVDIVIDIRPFRKDP EMVKHLVLILKCKKAVNWVVKSYD------VKGSLKVIAP---NSIGFGKESERSMAMTKSIRKDMPSTQ----ENLVRW AFD----------------------------NGYSPVTSYTMAPEANRFHLWLENN---------------------EEM SDEEEHSTPPELRILLGGSPLPSPENPSISGG------SFPFPFPPINRKGRPEEKGEDGLPRPKKTPN----------- -------------------PILPLFPSLREPQEAQGR--VDIAFSVKCNEEKMVVAIEKESLQA-------SGYTGTELS LSDPACKAKTN---------GSH-FILESPLEGCGTQQRLSAPDSMVYYN-SIIMPVSAPGDSSGWPTDYEDLESGN-NG FPGDTDE-GDS--FFISRPEIVVFNCSLRQTGMQ------DVFH-------QPQVQNITFNMELYDTDLFMVPI-PG--- ILEVVENGHIYVEVSVTKADQDVGFAIQTCFISPNSNSDRMSDYTIIENICPKDESVRFYSTQKTHFSRLHAQM------ ------------------------------------------------------------------DKKRFSFMLKPIFN TSLLFLQCELTLCTKKEATNHR-LPKCVP-----------PDEACTSLDATMIWAMMQNKKTFTKPLVVVHGAGT----- IDPTITNP-EISPPI---LLGL------------DTLTVMGIAFAAFVIGALLTGALWYIYSH----------------- ------------------------------------------------TGETAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSTT----------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Gallus_gallus_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MSSSC------------VTPVF-ALMILCF------ADAGPVPRSECVLSPVNSSHPVHALLESFTVLSGC ASRGT---------------------------------TGLPQEVHVLNLRN-PDEGLDHHER---EVTLHLTPIS---- -----------------------SVHIHQKPLVFLLNSPLPLVWKLKTERLAPG-------------------IRRVFFV SSGSIVWFEKGNFSLSAETEEKNFPERNEHLLQWAQKEYGAVTSFTELKISRNIYIKVGE-------------------- ---DQVFPPTCNIEKNFLSLNYLAGYLQPKR-AEGCLMSNLVQEREVHIIELITPNSNPY--SAFQVDIIVDIKPSQPGA KLERNVVLILKCKKSVNWVIKSHD------VQGKLEVITS---NSIGFGKETERSMTMSKSVIPDIPSSH----ESLIKW AYE----------------------------HKYSPVTSYTKAPVANRFHLQLEHT---------------------EEM NDEEDHSLPPELTELLHGAKNPALS------------DGLTFPFHINRGGH---ETGGEGIFPSRDSVDT-LI------- ----------------NHDFEHSLS-KHKEPEEVQGS--ADVALSIKCDDKVMTVAVEKDSLQA-------SGYTRTELS LLDHSCKARMN---------GTH-FILESLPNKCGTR-TSYILDKIVYFN-SIVIQLSSPAEGS--SFDDDDMESGD-NG FPGDADE-GDV--TFSNWP-EIAFNCTLHQPEKD--FFNPAMFWPP-----EPHITNVTFNMELYKTDLFLAPS-QG--- LFSVAENGPIYVEVSVTKADISLGFAIQTCFVSPFSNPDRMSDYTIIENICPKDESVKFYSTEKLNFPIAHAQK------ ------------------------------------------------------------------DKKRFSFVFKPIFN ISLLFLHCELTLCTNIDKDTQR-LPKCVP-----------PDEACTSLNVDMILAMMHNKKTFTKP-LVITHEGKPED-- S--SLPKSNVRQPSV---FYGL------------DTLTVVGIAFAAFVIGALLTGALWFIYSH----------------- ------------------------------------------------TGEAAGRRQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSSSAT---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Anolis_carolinensis_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MTSSC------------IIPVF-ALMVGCL------TSAGPVPTNRCVLSPVNSSHPVQALLESFTVLSGC ASKGT---------------------------------ALLPQEVHVLNLRS-PEEGLGHHER---EVALHLNPIS---- -----------------------SIHTHQKPLVFLLNSPVPLVWKVKTERLAPG-------------------IPRFFIV SAGSLVLFEKENFSLSAKTEEKPLPQGNRHLLQWAQKEYGAVTSFTELKISRNVYIKVGE-------------------- ---DQFFPTTCIIEKNFISLNYLAGYLQPKA-AEGCIVSSSSQDKEVHIIELITPDSNPY--SAFQVDIIIDIRPSRPDT TLVRDLVLILKCRRSVNWVIKSHD------VKGKLEAFAS---NSVGFGKEPECSMVMTKTILSDIPSSH----ESLIMW AYD----------------------------RGYSPVTSYTKAPVANRFHLRLEDT---------------------EEM NDEEDHFLPPELEELLRG-IKPQSEPI----------PSLEFDFPHDK---------VEGTFPSTDMEDSDMV------- ----------------NHGFGQFFH-KVSEPEEVQGS--VDVALSVRCDDTSMTVTVAKDSLEA-------SGHIGTQLS LLDPKCRAKAN---------QTH-FILESSLHECGTRRIAYPLDNIVYLN-SIVIQLPSPTESSGWPIDYEDMESGD-NG FPGDTDE-TDI--TFSSRPEIVVFNCTFHQPKAP----KPPMHWPP-----VTRVGNVTFGMELYKTDLFHTPT-QG--- FFSVAENDQIFVEISLTKAERSLSFAIQTCFISPHSYPDRMSEYTIIENICPKDESVKFYNIPKTNFLMLNAQM------ ------------------------------------------------------------------DKKHFSFMFKPIFN TSLLFLHCEVTLCTRKEKDTRG-LAKCIP-----------PDEACTFLNVDMILAMMQNKKSFTKPLAVITHKGKSEE-- KS-SYPKPPETLPPV---FYGL------------DTVTVVGIAFAAFVIGALLTGALWFIYSH----------------- ------------------------------------------------TGEPAGRQQVPTSPPASENSSAAH-------- ------------------SIGSTQSTPCSSNSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Xenopus_tropicalis_TGFBR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------VTLHLAPIS---- -----------------------SISVHQKPLVFILNSPSPLTWVLKTEGFAAG-------------------VRRFFFV SQGSSVKYEAENFTMFTETVEKHLPQGNEHLLQWAQKNYEAVTSFTEAKLSKNIYIKVGE-------------------- ---DPVFPSICKIEKNFLSLNYLARYLQPQP-AQGCKLTASNEEREVHIIELDAPSSKQYS--SFQVDIIIDIRPLHSDS MLARNLVLILKCKNAVNWVIKTHN------VKGKLEVLAG---NTVSFGKDADKSLFTSKSVIPNMPSTK----ASLMKW AFD----------------------------RGFSPVTSYTYAPIANQFHIRLFDD---------------------IEL NDEDDHLIPPELIELLDTHKS-----------------FIPEKYSPIDRENGKEGEAAHSSKDILDSIIHG--------- ------------------LGIEELSPEPKEPEEVQGN--INIALSVKCDNQKMEASVEKESLQS-------DIYPYQQYN LKGCSDRCKLA---------TVH-IVYSPQLYGCVTLIRSLNPKAIIYISNLIVIQLSPPTEGSGWSSDYVDLESGD-NG FPGDTDE-IEIGLPYLKRPEIVVFNCTVPQETMS--SEDVVIFERP-----ESTINNVTFNMDLYKTDLFLTPS-QK--- LFSVAENGQVYVEVSVTKAEKDLGFAIQTCFISPHSNPDIMSEYTIIENICPKDESVKFYNVKRMNFPVLAEQM------ ------------------------------------------------------------------DKKRFSFMFKSLFN NSLLFLHCELTLCTTNGKEMEG-LPKCIP-----------PDEACTSLNVEMIVAMMQNKKTFTKPLAVITPAVKTP--- -GPSLKGPPDHQESV---FYGL------------DTPTVVGIAFAAFIIGALLTGALWFIYSH----------------- ------------------------------------------------TGETSERQQVPTTPPASENSSAAH-------- ------------------SIGSTQSTPCSSNSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Danio_rerio_TGFBR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------MWLTAHIHPSAILLLTLSS-----------------LASAGPLSRSPCELLPVGVGHPVQAMLKSFTALSGC ASRGT---------------------------------TSHPQEVHIINLRKGSAQGAREKMA---EVALHLRPIQ---- -----------------------SLHVHQKPLVFILNSPQPILWKVRTEKLAPG-------------------VKRIFHV AEGSEVHFEVGNFSKSCEVKVETLPHGNEHLLNWAHHRYTAVTSFSELRMAHDIYIKVGE-------------------- ---DPVFSETCKIDNKFLSLNYLASYIEPQP-STGCVLSGPDHEQEVHIIELQAPNSS----SAFQVDVIVDLRPLDGDI PLHRDVVLLLKCEKSVNWVIKAHK------VMGKLEIMTS---DTVSLSEDTERLMQVSKTVKQKLPAGS----QALIQW AEE----------------------------NGFNPVTSYTNTPVANHFNLRLREQ---------------------VSD VGIMDEGMLPPFSILRNINPLPKPSARDAPPR-----NGFPFPFLPMDQDQ-----SFPPLMPPHEDSV----------- -------------------------FLAGGPEEHQGS--ADVGFNVQCEKNKMVVSIDKETLQA-------NGFGKPNIT LQDSQCKATSN---------ATH-YILETPLSGCQTSKIPSHPSPVVLYINAIVISQSEQKDGSGWPVDDEDMEPGEVLL PGDALPELTERILPVNGHHATILFNCTYRKNQDSPFDTDAGSDDFL-----VDSTANVTFNMELYNN-HFQFPNSQP--- FLTVTENRPVFVEIAATKADPNLGFMIQTCFISPDSNPAVQSEYVVIENICPKDDSVVYY-PQRGDFPIPHAQM------ ------------------------------------------------------------------DKKRFSFTYRSKFN VSLLFLHCEMSLCSRRNDKEMN-LAECML-----------PDEACTSLSIESILLIMMNTKTLTKPIVVISDDMP----- --VTIKVPREESPPRQGIIYVL------------DTPTVVGIAFAAFVIGALLTGALWFIYSHTG--------------- --------------------------------------------------GTAAGQQVPSCPPVSENSSAAH-------- ------------------SIGSTQSTPCSSSSNA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------ >Takifugu_rubripes_TGFBR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------VVGECVHFVFCISCF-----------------VFTAEPLFRSPCELLPVGLGHPVQAMLKSFTAMSGC ASRGT---------------------------------ISLPQEVHIINLRGHEAEGVSNPFP---QVELHLKPIQ---- -----------------------SLLRHQKPLVFVLNSPQQLMWKIKTENLAPG-------------------IKHTFHV SEGSEVIFLPGNFSLACQIQNENLPHGNEHLLNWAQKKYSAVTSFTELKTTQDIYIKVGE-------------------- ---DPVFSDTCKIDTKFLSLNYLGSYMEPQP-SKGCILSGPDKDREVHIVELQAPNSSRFFCSAFQVDVIVELRPMKDGI LLHRDVVLLLRCAKSVNWVIQTHG------VGGRLVIVAS---DTISVSSNPEGAVQLVKSPKQRLPSGS----QALIMW AGD----------------------------HGYNPVTSYTNTPVANHFSIHLRESGMVNSTTDLSSAAKYNQVTVSPVA VDPTKSMFPPDLSILRHSD--PRPGEGAVSGR-----SSLPFPFPPPV-----------DFPPHSHNRP----------- -------------------------WENIDAEDHQDA--LNIGHSVQCEDTKMVVSIEKESLEA-------NGFTNANLV LQDPACKASVN---------STH-YILETPLTGCQTTVYPIQGSPMALYINSVSISRAENPDASGGPLGFVNIKD---LM FPRDPSELVFVYDS----IPFLQFNCTYRMNQPSSNALPSIVPVPG-----TDPVKNASFTIELYDTLPFNNPSRQA--- FYTVSQNQQVFAEVTSAASEPELSFTIISCFISPNSNPAVTSDYTLIEMVCPKDDSVKFY-PQR-DVPFSRAHV------ ------------------------------------------------------------------EKKHFAFKFNSKFN LSLLFLHCEMSLCSKVSQTDSN-LPPCLK-----------SNDTCDSISLSNIMIMMMNTKISTKPLVVLDAPP------ --GQAPSPAG--SNISDPVAVL------------DTPTVVGIAFAAFVIGALLTGALWFIYSHTG--------------- --------------------------------------------------ETAGTQELQKPPPTSENSSTAH-------- ------------------STGSTQSTPCSSSSTA---------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------