>Homo_sapiens_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLTTIRGDGAP------ ----APSGPP---------------------------------------------------------------------- ---------PPGSGRASGKHGQP--------------KMSRS-ASESASSS------------GTA-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Mus_musculus_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLTTIRGDGAP------ ----APSGPP---------------------------------------------------------------------- ---------PPGTGRSSGKHSQP--------------KMSRS-ASESAGSS------------GTA-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Pan_troglodytes_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLTTIRGDGAP------ ----APSGPP---------------------------------------------------------------------- ---------PPGSGRASGKHGQP--------------KMSRS-ASESASSS------------GTA-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLTTIRGDGAP------ ----APSGPP---------------------------------------------------------------------- ---------PPGSGRSSGKHGQP--------------KMSRS-ASESAGSS------------GTA-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Monodelphis_domestica_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LLFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLTTIRGDGAP------ ----VPSGPP---------------------------------------------------------------------- ---------PSATVRTSGKHGQP--------------KMSRS-ASESAGSS------------GTA-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gallus_gallus_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------KLNWFVCLFFSR-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLSTIRGDSS------- ------STVP---------------------------------------------------------------------- ---------PSVTVRTSSKQSQP--------------KTSRS-ASEGTGSSVCTCCSVCRLLRGKRS------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Anolis_carolinensis_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWIISRLVV-LIFGTLYP---------------AYYSYKAVKSKD-IKEYV--- -----KWMMYWIIFALFTTAETFTDIFLC-WFPFYYELK-------IAFVAWLLSPYTKGSS-LLYRKFVHPTLSSKE-- -------KE-IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKSQGALSERLR-SFSMQDLTTIRGESSS------ ----TVTPSP---------------------------------------------------------------------- ---------PPPPAPSGSVRSSS--------------KESRSKASKSASDS-----------IGRS-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLIFGTLYP---------------AYSSYKAVKSKD-VREYV--- -----KWMMYWIIFALFTTVEVITDIFLC-WLPFYYELK-------IAFVVWLLSPYTKGSS-VLYRKFVHPTLSSKE-- -------KD-IDEYLCQAKDKSYDTLMHFGRKGLNVAATAAVMAATKGQGVLSERLR-SFSMQDLSSFQAEG-Q------ ----TNSASSVTTQPAA--------------------------------------------------------------- -----------AQHRTRTMMRSKS----------------ETGYSKASS------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP1b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLVFGTLYP---------------AYSSYKAVKSRD-LKEYV--- -----KWMMYWIIFALFTTVEVFTDMFLC-WLPFYYELK-------IAFVVWLLSPYTKGSS-VLYRKFVHPTLSSKE-- -------KD-VDEYIGQTKEKICDTLVHYGRKGLNVAATAAVMAATKGQGVLSDKLR-SFSMQDLSAYQSD--------- ----PAEADPGPTAPAA--------------------------------------------------------------- -----------AQQRTKTMLRSKS----------------EGYSKGETT------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Tetraodon_nigroviridis_REEP1b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVIVFGTLYP---------------AYSSYKAVKSRD-LKEYV--- -----KWMMYWIIFALFSTVEVFTDMFLC-WLPFYYELK-------IAFIVWLLSPYTKGSS-VLYRKFVHPTLSSKE-- -------KD-VDEYIGQTKDKICDTLVHFGRKGLNVAATAAVMAATKGQGVLSDKLR-SFSMQDLSAYQSD--------- ----PAHADPATAAP----------------------------------------------------------------- -----------AQQRTKSMMRSKS----------------ESYNRGERT------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gasterosteus_aculeatus_REEP1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVIVFGTLYP---------------AYYSYKAVKSKD-VKEYV--- -----KWMMYWIIFALYTAVEVFTDMFLC-WIPFYYELK-------IAFVVWLLSPYTKGSS-VLYRKLVHPTLSSKE-- -------KD-IDEYICQAKDKSYDTLVHFGRKGLNVAASAAVLAATKSQGVLSDRLR-SFSMQDLSAYQSD--------- ----PVNTGAGPTQPAA--------------------------------------------------------------- -----------APQRTRSMMRSKS----------------ESCNKEKTA------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Oryzias_latipes_REEP1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLVFGTLYP---------------AYSSYKAVKSKD-VKEYV--- -----KWMMYWIIFALFMTVEAFTDMFLC-WLPFYYELK-------IAFVVWLLSPYTKGSS-VLYRKFVHPTLSSKE-- -------KD-IDDYICHAKDKSYDTLLHFGRKGLNVAATAAVMAATKGQGVLSDRLR-SFSMQDLSSYQSD--------- ----PVTSSPGSAQSGA--------------------------------------------------------------- -----------TQHRTRPIMRSKS----------------ESY-KGKTSL------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Strongylocentrotus_purpuratus_REEP1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVAYL-LSRLVVLVFGTLYP---------------AYYSYKAVKTRN-VKEYV--- -----KWMMYWIVFALFSCVETVADIFASI-LPFYYEIK-------ILFIFWLISPWTKGST-YLYRKCIHPALSKKE-- -------QE-IDEYINQASTRGYEALKRVGRNGMTLAANAVMTSAIKGQTSLLDQIKVYSGIAIAAGTAIEDRRLPPPEG GDSQDEDVIAIETSTRVTRSQQDETDMGTMLTPELHDLDYGASTHGDLLQSLDKLDNRLREEREHEHYLRSGESEWGHED IHQQPDNDWDRDDRPDKDLEYLISDQYEDQPPQPKPRAKPRSPPRRKPTPPTHPIVDQDSESSDVERPATLRRSTSLRSS GKSRTYSSTENLSTSRGRYASTENLTKRQLSRRQEMMSRSLRHSTRQTSNRDAQERRPPSHQK----------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Homo_sapiens_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLIFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFAFFTTAETLTDIVLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLR-SFSMQDLTLIRDEDAL------ ----PLQRPDGRLRPSP--------------------GSLLDTIEDLG-------DDPALSLRSST--NPADSRTEASED DMG------DKAPKRAKPIKKAPK--AEPL-----ASKTLKTRPKKKTSG------------GGDSA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Mus_musculus_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLIFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFAFFTTAETLTDIILS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLR-SFSMQDLTLIRDEDAL------ ----PLQGPDGRLQPGP--------------------VGLLDTIEDLG-------DEPALSLRSST--SQPDPRTETSED DLG------DKAPKRTKPIKKVPR--AEPP-----ASKTLKTRPKKKSSG------------GGDSA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Pan_troglodytes_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLIFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFAFFTTAETLTDIVLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKG--VLSEKLR-SFSMQDLTLIRDEDAL------ ----PLQRPDGRLRPSP--------------------GSLLDTIEDLG-------DDPALSLRSST--NPADSRTEASED DMG------DKAPKRAKPIKKAPK--AEPL-----ASKTLKTRPKKKTSG------------GGDSA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------FPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKG-- -------KEEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLR-SFSMQDLTLIRDEDAL------ ----PLQGPDGRLQPGP--------------------VGLLDTIEDLG-------DEPALSLRSSS--SQADPRTETSED DLG------DKAPKRTKPIKKVPK--AEPP-----ASKTLKTRPKKKSPG------------GGDSA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Monodelphis_domestica_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------LIFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFAFFTTAETLTDIVLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYITQARDKSYETMMRVGKRGLNLAANAAVTAATKGQGVLSEKLR-SFSMQDLTLIRDDEAL------ ----PLHGPDARLRSSA--------------------SGLLDPIEDL--------DDAGLSLRSSSG-SQSDTRTEASED DLG------DKTAKRVKSIKKVPK--TEP------VLKTLKTRPKKKPTS------------GGETA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Anolis_carolinensis_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRLVVLVFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFAFFTTAETLTDIILS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYISQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLR-SFSMQDLTLIRDDDTV------ ----HLRSPESHMRTSS--------------------TGLHEAVDDSGASCYSSSEEMVVSQRHTG--AQSDTKTDPSDD DTG------DKVPKRTQSLKAPKKVTKSEP-----PQKTVKARPKKKVTSSSA---------VGESA------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRMVVLAFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFALFTTAETITDMLLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------RE-IDEYITQAKDRSYDTMMRFGRRGLNIAATAAVTAATKGQGVLSEKLR-SFSMQDLTLIQNEDEL------ ----QLDGGDDTHTAAT----------LPRAK----TATRTVRATPVPA--------DTESQHSSRSDDQSDSRTEHSDE DAA------DKAPKRIAITRAAKKPAAAKTEQ---TTKTVKKAPKKKTTTANN---------VAESP------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRVVVLAFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFALFTTAETATDLFLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYIAQAKDRSYETMMRFGKRGLNLAANAAVTAASKGQGVLSDKLR-SFSMQDLTLINADDEL------ ----GLHTSEPRVRREPADDMSSGASTLPRAR----STARSLAANSLAD--------DASSQHGS---DQSDTRTEHSDE DVV------EKAAKRGSTAKTTKKTATVKTET---QTKPVKKPAKKKSSANT-----------AETP------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Tetraodon_nigroviridis_REEP2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWI-ISRVVVLAFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFALFTTAETATDLFLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYIAQAKDRSYETMMRFGKRGLNLAANAAVTAASKGQGVLSDKLR-SFSMQDLTLINAEDEL------ ----GLHPSDPRVRRDP--------------------VARLLAATSLAD--------DASSQHSS---DQSDTRTEHSDE EVA------EKIPTRGSTAKTAKKPAPP-------QTKTVKKPAKKKTTTNN-----------AET-------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gasterosteus_aculeatus_REEP2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ISRIVVLAFGTLYP---------------AYSSYKAVKTKN-VKEYV--- -----KWMMYWIVFALFTTAETATDLLLS-WFPFYFELK-------IAFVIWLLSPYTKGSS-VLYRKFVHPTLSNKE-- -------KE-IDEYIAQAKDRSYDTMMRFGKRGLNLAATAAVTAATKGQGVLSDKLR-SFSMQDLTLINAEDEL------ ----SLHTSDVRMRRDAMDDLSSGSSTLPRAK-----STRQTRSTSVVDT----SHVDTSSQHGS---DQSDTRTEHSDE DAV------DKAPKRSASVRATKKPAAAKTET---QTKTAKKPTKKKVPTTN-----------AETP------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Homo_sapiensREEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ISRAVVLVFGMLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVIETVADQTVA-WFPLYYELK-------IAFVIWLLSPYTKGAS-LIYRKFLHPLLSSKE-- -------RE-IDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLR-SFSMHDLTTIQGDEPV------ GQRPYQPLPEAKKKSK----------------------PAPSESAGYGIPLKD--GDEKTDEEAE--GPYSDNEMLTH-- ----------KGLRRSQS-MKSVKTTKGRKE---VRYGSLKYKVKKRPQVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Mus_musculus_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ISRAVVLVFGMLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVIETVADQTLA-WFPLYYELK-------IAFVIWLLSPYTRGAS-LIYRKFLHPLLSSKE-- -------RE-IDDYIVQAKERGYETMVNFGRQGLNLAAAAAVTAAVKSQGAITERLR-SFSMHDLTAIQGDEPV------ GHRPYQTLPEAKRKGK----------------------QAT-ESPAYGIPLKD--GSEQTDEEAE--GPFSDDEMVTH-- ----------KALRRSQS-MKSVKTIKGRKE---VRYGSLKYKVKKRPQVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Pan_troglodytes_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------LMMWLLV-ERALIQLVFGMLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVIETVADQTVA-WFPLYYELK-------IAFVIWLLSPYTKGAS-LIYRKFLHPLLSSKE-- -------RE-IDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLR-SFSMHDLTTIQGDEPV------ GQRPYQPLPEAKKKSK----------------------PAPSESAGYGIPLKD--GDEKTDEEAE--GPYSDDEMLTH-- ----------KGLRRSQS-MKSVKTTKGRKE---VRYGSLKYKVKKRPQVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus___REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------M-ISRAVGLVFGMLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVIETVADQTLA-WFPLYYELK-------IAFVIWLLSPYTRGAS-LIYRKFLHPLLSSKE-- -------RE-IDDYIVQAKERGYETMVNFGRQGLNLAAAAAVTAAVKSQGAITERLR-SFSMHDLTAIQGDEPV------ GHRPYQTLPEAKRKGK----------------------QAT-ESPAYGIPLKD--GSEQTDEEAE--GPFSDDEMVTH-- ----------KGLRRSQS-MKSVKTIKGRKE---VRYGSLKYKVKKRPQVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gallus_gallus_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------LVHWM-ISRSTRLVFGMLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVTETITDLTIS-WFPLYYELK-------IAFVIWLLSPYTRGAS-LMYRKFLHPLLSSKE-- -------RE-IDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLR-SFSMHDLTTIQGDEPV------ GQRPYQTLPETKKKTR----------------------ASANESAGF--PLEKNPGDDRTDEEVE--GTHSEDEMFAQ-- ----------RGLRRTQS-MKSVKTVKGRKE---IRYGSLKYRVKKRPNVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Anolis_carolinensis_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------NAGWM-MLGVVMLVFGMLYP---------------AYYSYKAVKTRN-VKEY---- ----VRWMMYWIVFALYTVTETIADLMIS-WFPLYYELK-------IAFVIWLLSPYTRGAS-LIYRKFLHPLLSSKE-- -------KE-IDEYIVQAKERGYETMVNFGKQGLNLAATAAVVAAAKGQGAITEKLR-SFSMQDLTAIQGDEPV------ GQRPYQTLPDTKRRGKS---------------------SNTSENLGLYVTERQ--TSCKSFHSCQ--DPDSRAPITIH-- ----------RGQNLSNIFIKEIWTVGGQKKRE-MRYGSLKYKVKRRPQVYF---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP3b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ISRSVVLVFGNLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALFTVVETVADLTIA-WFPLYYEIK-------IAFVIWLLSPYTRGAS-VIYRKALHPLLSSKE-- -------RE-IDDYIVQAKERSYETMVNFGKQGLTIAATAAVSAAVKGQGAITEKLR-SFSMHDLTQIPQDD-------- GYSSYASNPARRAIMDQ---------------------PDGAEYY-----HGD--DDDRSDEDSK--PVFSEDEAVSH-- ----------HGLRRSQS-VKVTRSK-LRRD---ARYGSLKIKGRKRPGINATTYSNMES-------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWL-ISRSVVLVFGTLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVAETITDLTLS-WFPLYCELK-------IAVVIWLLSPYTRGAS-LIYRKCLHPLLSSKE-- -------RE-IDEYIVQAKERSYETMVSFGKQGLSIAATAAVSAAVKGQGAITEKLR-SLSMHDLTQINQQDDRGGNQFF HFSSHSASPAVRRSQNA---------------------DSAAEDE----YFYD--NGERTDEDAD--PTFSEDEALTQ-- ----------RGLRRSQS-VKITRSR-VRKD---ARYGSLKIKGKKRSALSSVNYVFNLDS------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Tetraodon_nigroviridis_REEP3a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWL-ISRSVVLVFGTLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVAETITDLTLA-WFPLYYELK-------IAVVIWLLSPYTRGAS-LIYRKCLHPLLSSKE-- -------RE-IDEYIVQARERSYETMVSFGKQGLSIAATAAVTAAVKATGCLTADLS-SDSCLKSCAIESTD----LCWR RFQSKSIVVEGRSSQPV---------------------NSPTY------YFYD--NEDRTDEEAE--PTFSEDEALTQ-- ----------RGVRRSQS-VKLTRSR-VRKD---TRYGSLKIKGKKRPALSS---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Oryzias_latipes_REEP3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ISRSVVLLFGTLYP---------------AYYSYKAVKTKN-VKEY---- ----VRWMMYWIVFALYTVVETITDLTVA-WFPLYYELK-------IAFVIWLLSPYTRGAS-LIYRKCLHPLLSSRE-- -------RE-IDDYIVQAKERSYETMVNFGKQGLSIAATAAVTAAVRGQGAITEKLR-SLSMHDLSQIGQQDEG-GNQLF QYSSRSANPAARRAQSS---------------------EHAADEN-----YYD--EEDRSDEEAE--PTFSEDEAVSQ-- ----------KGLRRSQS-VKMTRSR-ARKD---ARYGSLKIKGKKRPALSAVNYSTMRDTPS----------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Homo_sapiensREEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ICRLVVLVFGMLCP---------------AYASYKAVKTKN-IREYV--- -----RWMMYWIVFALFMAAEIVTDIFIS-WFPFYYEIK-------MAFVLWLLSPYTKGAS-LLYRKFVHPSLSRHE-- -------KE-IDAYIVQAKERSYETVLSFGKRGLNIAASAAVQAATKSQGALAGRLR-SFSMQDLRSISDA--P----AP AYHDPLYLEDQVSHRRP---------------------PIGYRAGGLQ--------DSDTEDECW-----SDTEAVPRAP ARP-----REKPLIRSQS-LRVVKRKPPVRE---GTSRSLKVRTRKKTVP-SDVDS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Mus_musculus_REEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ICRLVVLIFGMLYP---------------AYASYKAVKSKN-IREYV--- -----RWMMYWIVFAIFMAAETFTDIFIS-WFPFYYEFK-------MAFVLWLLSPYTKGAS-LLYRKFVHPSLSRHE-- -------KE-IDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLR-SFSMQDLRSIPDT--P----VP TYQDPLYLEDQVPRRRP---------------------PIGYRPGGLQ--------GSDTEDECW-----SDNEIVPQPP VRP-----REKPLGRSQS-LRVVKRKPLTRE---GTSRSLKVRTRKKAMP-SDMDS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Pan_troglodytes_REEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ICRLVVLVFGMLCP---------------AYASYKAVKTKN-IREYV--- -----RWMMYWIVFALFMAAEMVTDIFIS-WFPFYYEIK-------MAFVLWLLSPYTKGAS-LLYRKFVHPSLSRHE-- -------KE-IDAYIVQAKERSYETVLSFGKRGLNIAASAAVQAATKSQGALAGRLR-SFSMQDLRSISDA--P----AP AYHDPLYLEDQVSHRRP---------------------PIGYRAGGLQ--------DSDTEDECW-----SDTEAVPRAP ARP-----REKPLIRSQS-LRVVKRKPPVRE---GTSRSLKVRTRKKTVP-SDVDS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus_REEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWM-ICRLVVLIFGMLYP---------------AYASYKAVKSKN-IREYV--- -----RWMMYWIVFAIFMAAETFTDIFIS-WFPFYYEIK-------MAFVLWLLSPYTKGAS-LLYRKFVHPSLSRHE-- -------KE-IDACIVQAKERSYETMLSFGKRSLNMAASAAVQAATKSQGALAGRLR-SFSMQDLRSIPDT--S----AP TYQDPLYLEDQAPRRRP---------------------PIGYRPGGLQ--------DSDTEDECW-----SDNEIAPQPP VRP-----REKPLSRSQS-LRVVKRKPLVRE---GTSRSLKVRTRKKTIP-SDLDS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Monodelphis_domestica_REEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MVSWV-ISRLVVLVFGMLYP---------------AYASYKAVKTKN-IREYV--- -----RWMMYWIVFAFFMTVETFTDIFIS-WFPFYYEIK-------IAFVVWLLSPYTKGAS-LLYRKFVHPALSYRE-- -------KE-IDSYIVKAKERSYETVLSFGKRGLNIAATAAVQAAAKSQGALAGRLR-SFSMQDLRSIPDN--P----AP PYQDPLYLEDQELHRRP---------------------PIRYRPGGLQ--------DSDTEDECW-----SDSQTKAHTL PRP-----REKPLVRSQS-LRIGKRKPLVRE---STSRSMKVRTRKKAVAPVELDS------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Anolis_carolinensis_REEP4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------KVN---WEKCTKLVFGMLYP---------------AYASYKAVKTKN-IREYV--- -----RWMMYWIVFALFMATETVADTFVS-WFPFYYEIK-------MAFVVWLLSPYTRGAS-LLYRKFIHPTLSRKE-- -------KE-IDQLILQAKERSYETLVSFGKKSLNVAATAAVQAAHKSQGALTGRLR-SFSMQDLRSIPDA--A----PV HYSDPLYLEEDQLRRRP---------------------IAGWRAAPQPQG------SDSNEEDCW-----SDSGLSAGPR LQSKEPGLP-KPLARSQS-LRVVKKKPPTKE---GSVRLVRSRPRKKVVD-QEN-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Homo_sapiens_REEP5 -------------------------------------------------------------------------------- ----------------------MSAAMRER-----FDRFLHEKNCMTDLLAKLEAKTGVNRSFIALG------------- -----------------VIGLVALYLVFGYGASLLCNLIGFGYP---------------AYISIKAIESPN-KEDDT--- -----QWLTYWVVYGVFSIAEFFSDIFLS-WFPFYYMLK-------CGFLLWCMAPSPSNGAELLYKRIIRPFFLKHE-- --------SQMDSVVKDLKDKAKETADAITKEAKKAT-------------------------VNLLGEEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Mus_musculus_REEP5 -------------------------------------------------------------------------------- ----------------------MSAAMRER-----FDRFLHEKNCMTDLLAKLEAKTGVNRSFIALG------------- -----------------VIGLVALYLVFGYGASLLCNLIGFGYP---------------AYISMKAIESPN-KDDDT--- -----QWLTYWVVYGVFSIAEFFSDLFLS-WFPFYYMLK-------CGFLLWCMAPSPANGAEMLYRRIIRPIFLKHE-- --------SQVDSVVKDVKDKAKETADAISKEVKKAT-------------------------VNLLGDEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Pan_troglodytes_REEP5 -------------------------------------------------------------------------------- ----------------------MSAAMRER-----FDRFLHEKNCMTDLLAKLEAKTGVNRSFIALG------------- -----------------VIGLVALYLVFGYGASLLCNLIGFGYP---------------AYISIKAIESPN-KEDDT--- -----QWLTYWVVYGVFSIAEFFSDIFLS-WFPFYYMLK-------CGFLLWCMAPSPSNGAELLYKRIIRPFFLKHE-- --------SQMDSVVKDLKDKAKETADAITKEAKKAT-------------------------VNLLGEEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus_REEP5 -------------------------------------------------------------------------------- ----------------------MSAAMRER-----FDRFLHEKNCMTDLLAKLEAKTGVNRSFIALG------------- -----------------VIGLVALYLVFGYGASLLCNLIGFGYP---------------AYISMKAIESPN-KDDDT--- -----QWLTYWVVYGVFSIAEFFSDLFLS-WFPFYYMLK-------CGFLLWCMAPSPSNGAELLYRRVIRPIFLKHE-- --------SQVDSVVKDVKDKAKETADAISKEVKKAT-------------------------VNLLGDEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Monodelphis_domestica_REEP5 -------------------------------------------------------------------------------- ----------------------MSATLKQR-----FEQFLHQKNCMTDLLAKIESKTGVNRAYVALG------------- -----------------VIGLVALYLVFGYGASLLCNLIGFGYP---------------AYISIKAIESPN-KDDDT--- -----QWLTYWVVYGVFSIAEFFSDLFLS-WFPFYYMLK-------CGFLLWCMAPSPSNGAEMLYRRLIRPFFLKHQ-- --------SQMDSVVKDLKDKAKETADALAKEAKKAT-------------------------VNLLGDEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gallus_gallus_REEP5 -------------------------------------------------------------------------------- ----------------------MTAAMRQR-----FDRFLHEKNCMTAVLERIESKTGVDRTYIAIA------------- -----------------VLGVVAVYLVIGYGASLLCNIIGFGYP---------------AYVSIKAIESPN-KDDDT--- -----QWLTYWVVYGVFSIAEFFSDIFLS-WFPFYYMLK-------CGFLLWCMAPSPSNGAEFLYHRIIRPFFLKHE-- --------AQLDNVVKDLKDKAAETADTIAKEAKKAT-------------------------VNLLGEEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Anolis_carolinensis_REEP5 -------------------------------------------------------------------------------- ----------------------MTASMRER-----FDKFLHEKNCLTNVLEKIEAKTGVNRTYVAIA------------- -----------------IFAALAIYLVIGYGASLLCNLIGFAYP---------------AYISIKAIESPN-KDDDT--- -----QWLTYWVVYGIFSVAEFFSDIFLS-WFPFYYMMK-------CGFLIWCMAPSPSNGAEFLYHRIIRPFFLKHE-- --------AQLDNVVKDLKDKAKETADTFSKEAKKAT-------------------------IGLLGEEKKST------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP5a -------------------------------------------------------------------------------- ----------------------MAAALKQR-----FDNALHEKNMVTDLLAKIEAKTGVNRSYIAYA------------- -----------------VIAFIAIYLVIGYGASLLCNLIGFVYP---------------AYISIKAIESPA-KDDDT--- -----KWLTYWVVYGVFSVVEFFADIFLS-WFPFYFLAK-------CAFLVWCMAPTPSNGSIMLYTRIIRPFFLKNE-- --------AKIDNVMKDLTDKAAGAADKIKDEAKKAT-------------------------ANIMFEEKKHY------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP5a -------------------------------------------------------------------------------- ----------------------MSQGLKER-----FEKFLHEKNLLTDLLGRVEEKTGVNRTYIAAA------------- -----------------LVVVVSVYLVIGYGASLLCNLIGFLYP---------------AYISVKAIESAT-KDDDT--- -----KWLTYWVVYGIFSVAEFFADIFLS-WFPFYYIGK-------CAFLVWCMAPTPSNGSVLIYNRIIRPFFLKNE-- --------AKIDDVVKNLKDKASEAADKIKDEAKRAT-------------------------ANIMFEEKKSS------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP5b -------------------------------------------------------------------------------- ----------------------KMNRYTER-----FATLLHEKNFATDLLAKLEEKTGVKREYIALG------------- -----------------LLSFVGLYLLFGYGASLLCNLIGFAYP---------------AYLSIKAIESNV-KEDDT--- -----QWLTYWVVYGLFSVLEAFSDIFLS-WFPFYYASK-------CLFLIWCMAPVQWNGSKILYTRVIRPFFLKHE-- --------ATMDNVVNNLSSTAKTITGTVTKEVVHVGLF-----------------------TTALNNDEKKIV------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gasterosteus_aculeatus_REEP5a -------------------------------------------------------------------------------- ----------------------MAQGLRER-----FEKFLRQKNLMTDILEKIETKTGVSRTYIALA------------- -----------------VVGIIAVYLVVGYGASLLCNLIGFLYP---------------AYISIKAIESAT-KDDDT--- -----KWLTYWVVYGLFSVAEFFADLFLS-WFPFYYIGK-------CAFLVWCMAPMSSNGSIQIYTRIIRPFFLRNE-- --------TRIDDAVKTLQDKASEAADKIKDEAKRAT-------------------------ANIMFEEKKSS------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gasterosteus_aculeatus_REEP5b -------------------------------------------------------------------------------- -----------------------MSQLKDR-----FVTLLHEKNFVTDQLATVEQKTGVKREYIALG------------- -----------------VLGFVGLYLLFGYGASLLCNLIGFAYP---------------AYFSIKAIESSV-KEDDT--- -----QWLTYWVVYGLFSIVEAFSDIFLF-WFPFYYIGK-------CLFLLWCMAPVTWNGSEIIYRRVIRPFFLKHQ-- --------ATMDSVVSDLSAKAKNITENVAKEAV----------------------------NRALNHEKDQ-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Oryzias_latipes_REEP5a -------------------------------------------------------------------------------- ----------------------MAQGLRER-----FERFLHKDNALTAVLAKLEARSGVSRTYISLG------------- -----------------VIGIIAVYLVIGYGASLLCNLIGFMYP---------------AYISIKAIESAT-KEDDT--- -----KWLTYWVVYGIFSVAEFFADIFLS-WFPFYYIGK-------CAFLVWCMAPIPSNGSVQIYHRIIRPFFLKNE-- --------ATIDDTVKNLKDKASDAADKIRDEAKKAT-------------------------ANIIFEEKKSS------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Branchiostoma_floridae_REEP5 -------------------------------------------------------------------------------- ------------------MAAAEVKSYREK-----LEKYLYEKNAFTDLLAKAEAKTGVKRVYIVYV------------- -----------------LLTILCLYLAIGYGAGFLCNLIGFVYP---------------AYASVKAIESER-KEDDT--- -----QWLTYWVVYSVFGLAEFWFDILLF-WIPFYYLLK-------CLFLLYCMAPGSYNGSEMIYQRIIRPFVLRHQ-- --------DKVDRFIDQAGKRAKEALDTEILILQFLPIEMAFP-----------------FYTTLLVALELQ-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Homo_sapiens_REEP6 -------------------------------------------------------------------------------- -----------------------MDGLRQR-----VEHFLEQRNLVTEVLGALEAKTGVEKRYLAAG------------- -----------------AVTLLSLYLLFGYGASLLCNLIGFVYP---------------AYASIKAIESPS-KDDDT--- -----VWLTYWVVYALFGLAEFFSDLLLS-WFPFYYVGK-------CAFLLFCMAPRPWNGALMLYQRVVRPLFLRHH-- --------GAVDRIMNDLSGRALDAAAGITRNVK-----------------------------PSQTPQPKDK------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Rattus_norvegicus_REEP6 -------------------------------------------------------------------------------- -----------------------MDGLRQR-----FERFLEQKNVATDALGALEARTGVEKRYLAAG------------- -----------------ALTLLGLYLLFGYGASLLCNVIGFVYP---------------AYASVKAIESPN-KEDDT--- -----VWLTYWVVYALFGLVEFFSDLLLF-WFPFYYAGK-------CAFLLFCMTPGPWNGALLLYHRVIRPLFLKHH-- --------VALDSAASQLSGRALDIAAGITRDVLQALARGRTLVTPASASESPAALEPD--PKSSQTTLLKHK------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Monodelphis_domestica_REEP6 -------------------------------------------------------------------------------- -----------------------MGSLKQR-----FHRFMEQKNFVTITLGKLEEVTGIQKNYLASGNVLRTS------- --------------FSCCICILGSIYIW-YGASLLCNLIGFIYP---------------AYASIKAIESPD-REDDT--- -----IWLTYWVVYGMFGLAEFFSDIFLF-WFPFYYAGK-------CAFLLWCMLPLACNGSQFLYNRLIRPIFLRHQ-- --------ASMDSLVTDLSGRALDTAASITREVLHALAQSRSMMATQVGPQ----------VAPRLPPESPNQISPAAEG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP6a -------------------------------------------------------------------------------- ----------------------MLNTVTER-----YDAFFKQKNVLTDFLAVLEEKTGVQKQYIAAG------------- -----------------VVSIVAFYLIFGYGASLLCNLIGFIYP---------------AYASIKAIESNN-KEDDT--- -----KWLTYWVVYGLFSVAEFFSDIFLF-WFPFYYAGK-------CLFLLWCMAPISWNGSQVIYTRVVRPFFLKHE-- --------AAFDNVVSDLSGKAKSAAETMAKEG------------------------------LTLLNSDKNK------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Danio_rerio_REEP6b -------------------------------------------------------------------------------- -------------------MFAIFTKIKDR-----VEAFLNEKNIVTDCLNKIEEKTGIKKRYLAYG------------- -----------------AAGVTGAFLLLGYGASLICNLIGFVYP---------------AYFSIKAIESPG-KEDDT--- -----QWLTYWVIYGFFSVGEFFSDIFLH-WFPFYYVCK-------CLFLLWCMAPVSWNGSQVLYRHVVRPFFLKHE-- --------AAVDGMVSNISVKAMSAAENVTREVLHTLVRNRTVG-----PAES--------EPRSLPSSAHTEPTVD--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Takifugu_rubripes_REEP6a -------------------------------------------------------------------------------- -------------------LLDIFSSIRER-----ADKFLSEKNVVTDFLGKVEEKTGIKKKILAFG------------- -----------------GVSLTGLYLVYGYGASLLCNLIGFVYP---------------AYYSIKAIESPC-KEDDT--- -----KWLTYWVVYGIFSLGEFFSDIFLY-WFPFYYAFK-------CLFLLWCMAPVSWNGSQIIYSKVVRPVFLRHE-- --------AMVDDMVNSLGGKAMNAAEHLTREVLTTLMKNKALVTPAPDASQT--------QTKSLPSTSGEAPAAG--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Tetraodon_nigroviridis_REEP6a -------------------------------------------------------------------------------- ----------------------IFSSVRER-----ADRFLSEKNVVTDFLGKVEEKTGIKKKILAVG------------- -----------------GVSLTGLYLVYGYGASLLCNLIGFVYP---------------AYYSIKAIESPC-KEDDT--- -----KWLTYWVVYGVFSLGEFFSDIFLY-WFPFYYAFK-------CLFLLWCMAPVTWNGSQVIYNKVVRPVFLRHE-- --------AMVDDMVSSLGGKAMDAAETLTREG----------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Tetraodon_nigroviridis_REEP6b -------------------------------------------------------------------------------- ----------------MVKEGPKMNQFKDR-----FVTLLHEKNFATDQLAKLEDKSGVKREYIALG------------- -----------------LLSFVGLYLLFGYGASLLCNIIGFAYP---------------AYLSIKAIESNV-KEDDT--- -----QWLTYWVVYGLFSVLEAFSDIFLS-WFPFYYVSK-------CVFLIWCMAPVSWNGSKILYTRVIRPFFLKHE-- --------AAMDNVVNNLSSTAKTLTGTVTKEAV----------------------------TRALSHEKSQ-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Gasterosteus_aculeatus_REEP6a -------------------------------------------------------------------------------- ----------------------IFSSIRDR-----VDKFLNEKNVVTDFLGTLEEKTGIRKKILAVG------------- -----------------AVSFTGLYLVYGYGAALLCNLIGFAYP---------------AYYSIKAIESPS-KEDDT--- -----KWLTYWVVYGVFSLGEFFSDIFLY-WFPFYYAFK-------CLFLLWCMAPIAWNGSQIIYNKVVRPIFLRHE-- --------AAVDDLVSDIGGRAMSAAENLTREA-----------------------------TKVAPSESSEEQPVR--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------- >Oryzias_latipes_REEP6 -------------------------------------------------------------------------------- -------------------LLDIFSSIKER-----AEKFLNEKNMVTDFLGKVEEKTGIKKKFIAAG------------- -----------------AVSLTGLYLVYGYGASLLCNLIGFAYP---------------AYYSIKAIESPC-KDDDT--- -----KWLTYWVVYGVFSLGEFFSDIFLY-WFPFYYAFK-------CLFLLWCMAPMSWNGSQIIYNKVVRPIFLRHE-- --------ATVDNMVSDLSGKAMSAAENLTREVLSTLVKNKTLVTPMATVAQS--------DTRSLPSSSAQTSGAK--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------