>Homo_sapiens_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELG---------------------------RVTAPC TPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAPGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGP PAPPQVGADGLYSSLPNGLGGP--------------PERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFF YGSLDPPSSGAKP---------PEQAPPSPPGV---------------------------------------------GS RQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------GPPGTAYPPAPRPG PLPGPHPSLGSGNEDEDDDEAGGEEDVD--------------DEVFEASEGARPGSRMP------LKSPVPFLPGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YTSLASLEALASPGPTQ------SPFFTFELPPQPP----------APRPDP PAPAPLAPLEPDSGTSSAADGPWTQRG--E-------------------------------------------------- --------------------------------EEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGS-----EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPEALSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNDGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRISGGSG---------------------------------SGSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGMILYLQK---------------------------------- ------------------------EEYKPGKALSETELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQKKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMASELREHRAAQL------------------- -----------------------------------------------GKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALL R-------------------------------------------------------VKL-------KAGSEELDAVEAAL AQA-------GSTEDGLPPSHSSPSLQPKPSSQPRAQR-------HSSEPRPGAGSGR----RKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Gorilla_gorilla_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELG---------------------------RVTAPC TPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAPGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGL PAPPQVGADGLYSSLPNGLGGP--------------PERLATLFGGPADTGFLNQVDTWSSPREVSSHAQRIARAKWEFF YGSLDPPSSGAKP---------PEQAPPSPPGV---------------------------------------------SS RQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------GPPGTAYPPAPRPG PCPGPHPSLGSGNEDEDDDEAGGEEDVD--------------DEVFEASEGARPGSRMP------LKSPVPFLPGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YTSLASLEALASPGPTQ------SPFFTFELPPQPP----------APRPDP PAPAPLAPLEPDSGTSSAADGPWTQRG--E-------------------------------------------------- --------------------------------EEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGS-----EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPEALSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNDGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRISGGSG---------------------------------SGSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGMILYLQK---------------------------------- ------------------------EEYKPGKALSETELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQKKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMASELREHRAAQL------------------- -----------------------------------------------GKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALL R-------------------------------------------------------VKL-------KAGSEELDAVEAAL AQA-------GSTEDGLPPSHSSPSLQPKPSSQPRAQR-------HSSEPRPGAGSGR----RKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Mus_musculus_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLIRRVVGPGPRGRDLG---------------------------RVTAPC TPLRAPPSPHIAPSPWGPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPASGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGISAPRPTPALGPGCNRKLRLEASTSDPLPAGGGSVLPGSRDPSRGP LVPPQIGADGLYSSLPNGLGGT--------------PEHLAMHFRGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFF YGSLDAPSSGAKP---------PEQVLPSR-GV---------------------------------------------GS KQGSGVAVGRAAKYSETDLDKVPLRCYRETDIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------GPHGTAQPPASRPS PCPGPSSSLGSGN---EDDEAGGEEDVD--------------DEVFEASEGARPGDHMPH--SGLLKSPVPFLLGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YSSLASLEALASPGPTQ------SPFFTFEMPPQPP----------APRPDP PAPAPLAPLEPDSGTSSAADGPWTQRR--E-------------------------------------------------- --------------------------------VEESDAGATLAPRKELPSPSHSEDSFGLGAAPLGS--S--EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPEALSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNDGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRVSGGSG---------------------------------SSSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGMILYLQK---------------------------------- ------------------------EEYQPGKALSEAELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQKKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMASELREHRAAHL------------------- -----------------------------------------------GKKARGKEADEQRQKEAYLEFEKSRYGTYAALL R-------------------------------------------------------VKM-------KAASEELDTIEAAL AQA-------GSTEDGCPPPHSSPSLRPKPTSQPRAQR-------PGSETRAGAGSTR----PKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Loxodonta_africana_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGSRGRELG---------------------------RVTAPC TPLRGPPSPRAAPSPWAPSSPTGQPPPGAQSSVVIFRLVEKASVRPLNGLPAPGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGVSPPRPTPALRPGSNRKLRLEASTSDPLPAGGGSVLPGSRGPLTGP PAPPQVGTDGLYSSLPNGLGGP--------------PEHLATLFRGPADTGLLNQGDTWSSPREVSSHAQRIARAKWEFF YGSLDPPSSGAKP---------PEQAPPSPPGV---------------------------------------------GS GQGSGVAVGRVAKYSETDLDTVPLRCYRETNIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------DPFSTVCLPAPRPV LCPGPHPSSGSE----DEDEAGGEEDVD--------------DEVFEASEGARPGTQMPH--HGPLKSPVPFLPGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YTSLTSLEALASPGPTQ------SPFFTFELPPQPP----------APRPDP PAPAPLALLEPDSGTSSAADGPWTQRG--E-------------------------------------------------- --------------------------------EEGTEAGAKLAPGREPSSPCRSEDSFGLGAAPLGS-----EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPSTLSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNDGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRVSGGSG---------------------------------SGSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGMILYLQK---------------------------------- ------------------------EEYQPGKALSEAELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQRKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMANELREHRATHL------------------- -----------------------------------------------GKKARGKEAEEQQQKEAYLEFEKSRYGTYAALL R-------------------------------------------------------VKL-------KAGSEELDAVEAAL AQA-------RSAEDGIPPCHSSSSLQPNTSSQPRAQR-------HGPEPRAGAGSGR----RKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Dasypus_novemcinctus_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRAAGPGPRSRELG---------------------------RVTAPC TPLRGPPSPHAAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVKPLNGLPAPGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSVLPGSRGPSLGP PVPSQVGTDGLYSSLPNGLGGP--------------PEHLATLFQGPTDTGLLNQGDNLSSPREVSSHAQRIARAKWEFF YGSLDPPSSVLSP---------PEQAPPAPPGV---------------------------------------------GS GQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------GPPGTALPPAPHPS PCPGPRSSLGSGN--EDEDEAGGEEDVD--------------DEVFEASEGARPGIRTPY--PGPLKSPVPFLPGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YTSLASLEALASPGPTQ------SPFFTFELPPQPP----------APRPDP SAPAPLAPLEPDSGTSSAADGPWTQRG--E-------------------------------------------------- --------------------------------EE-AEARAKLAPGREPPSPCHSEDSFGLGTAPLGS-----EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPGSLSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNDGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRVSGGSG---------------------------------SGSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGTILYLQK---------------------------------- ------------------------EEYQPGKALSEAELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFEAPTLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQKKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMASELREHRAAHL------------------- -----------------------------------------------GKKTRGKEAEEQRQKEAYLEFEPPLRSRPGSDG GX------------------------------------------------------VKL-------KAGSEELDAVEAAL AQA-------GDLEDGIPPSHSSPSLQPNTASRPRAQR-------HSSEPRAGAGSGP----RKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Myotis_lucifugus_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------MAQGAMRFCSEGDC AISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELG---------------------------RVTAPS TPLRGPPSPRVAPSPWAPSSPTGQPPPGARSSVVIFRFVEKASVRPLNGLPAPGG------------------------- -------------------------------------------------------------------------------- -------------------------LSRSWDLGGVAPPRPTPALGPGSNRKLRLEASTSDPLPAGGGSALPGSQGLLHGP PAPPQVRADGLYSSLPNGLGGP--------------SEHLATLFRGPADTGLLNQGDTWSSPREVSSHAQRIARAKWEFF YGSLAPPSSGAKP---------PEQAPPSPPGV---------------------------------------------GS GQGSGVAVGRAAKYSETDLDTVPLRCYRETNIDEVLAER----------------------------------------- --------EEADSAIESQPSSE--------------------------------------------GLPGTVRPPAPRPG PCLGPHASLSSG----DEDEAGGEEDVD--------------DEVFEASEGARPGTQMPH--LGPLKSPVPFLPGTSPSA DGPDSFSCVFEAILESHRAKGTS-----YTSLASLEALASPGPTQ------SPFFTFELPPQPP----------IPRPDP PVPAPLAPLEPDSGTSSAADGPWTQRG--E-------------------------------------------------- --------------------------------EEEAEAAAKQAPGKEPPSPCRSEDSFGLGVAPLGS-----EPPLSQLV SDSDSELDSTERLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYRLDGFRKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMTLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYFQCNPGALSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNEGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRVSGGSG---------------------------------SGSSPFLDL-TPEPGAAVYKHG ALVRKVHADPDCRKT--------PRGKRGWKSFHGILKGMILYLQK---------------------------------- ------------------------EEYQPGKALSEAELKNAISIHHALATRAR-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQASSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAVSSQKKFSRPLLPSAATRLSQ---EEQVRTHEAKLKAMASELQEHQAALL------------------- -----------------------------------------------GKKARGKEAEEQRQKEAYLEFEKSRYGTYAALL R-------------------------------------------------------VKL-------KAGSEELDVVEAAL AQA-------GSTEDGVLPPHSSPALQRNVSSQPRAQC-------HGSEPRAGAGSGR----RKP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Monodelphis_domestica_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------MA---------------------------SFTWPR PPAQSPPPPRPPFVRGSQGACAVRPPPGAVP--------FSTTRNPRSPLPFPRL------------------------- -------------------------------------------------------------------------------- -------------------------SSTVWGGG--YPSLSFPSIPGGNT------------------------------- ---------------------P--------------PAHWKSGLREQVQGAHMCCGDCCSSPREVSAHAQRIARAKWEFF FGSLDPPSSGSQARDQ---DQEWEQASVRVPRE---------------------------------------------EL GHSSEVTTGRVTKYSETDLDTVPLRCYRETDIDEVLAER----------------------------------------- --------EEADSAIESQPSSE---------------------------------------------PLGTAR--APQPA PRPGPSLDSAS-------EEEEAEEEVD--------------DEVFEASEGAQPVAMSP---CGPLKSPVPFLPGSSPSA DGPDSFSCIFEAILESHRAKGTS-----YTSLASLEALASPVPTQ------SPFFTFELPPNHL----------VTQLDS QMPAPLAPLEPDSGTSSAADGPWTEREEEE-------------------------------------------------- --------------------------------EEEAKRGASSTKDRAPPSPCHSEDSFGLGPLPVGS-----DPPLGQLV SDSDSELDSTEQLALGSTDT-----LS-NGQKA---DLEAAQRLAKRLYNLDGFKKA--DVARHLGKNNDFSKLVAGEYL KFFVFTGMNLDQALRV--FLKELALMGETQ-ERERVLAHFS-QRYHQCNPGALSSE----DGAHTLTCALMLLNTDLHGH N---IGKRMTCGDFIGNLEGLNQGGDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRRSLSELADP-NPKVIKRVSGGSG---------------------------------GGSSPFLDL-SPEPGAAIYKHG PLVRKVHADPDCRKT--------PRGKRGWKAFHGILKGMILYLQK---------------------------------- ------------------------EEYQPGTALAEEELKNAISIHHALATRAS-------------DYSKRPHVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAQSLEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAISSQKKFSRPLLPSSATRLSQ---EEQVRTHEAKLRAMASELREHKASQQQ-P---------------- -----------------------------------------------DRKGKSKEAEEQRQKEAYLEFEKSRYGTYAALL R-------------------------------------------------------AKL-------KAGSEELEAVEAAL CQAVP-----GGVEDGLPASCSSPTLQPQPPPHSRPHR-------SGPEPRAGGSTRQ-----KP--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Gallus_gallus_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------MAQAGGLVRLPPAEGCTASPPPFSHHGDR RPWPPISSSPEPGRHSPPRCLTPNLNAGRLHLMRKGLAPETRRCPPGLYNSTGSLARKPTEMGPFGNGGCPGGGRLTAPC TPRRGHPAPGLT--SPGSRSPLVAPE--GRSSVVTFRFIEKASVRPLSGPQENGPAE----------------------- -------------------------------------------------------------------------------- ------------------------PGGGWR------VPPGQPRPQDQLLRSLKLEASASDPLLAS--CRSPGETRPHEGR RDAHSLTTSCLSSSLTNGLQAP--------------PRDVPTS--------PWLQGSAWPCPRQSSAHAQRIARAKWEFF YGSLGAPKTGSSAPV--------TEPPLQPSHPLPVEPPSSLPEHGLSHV------E----------VEIEVSPAGGRQQ GSCETGIIRRAVKYSETDLDTVPLRCYRETNIDDILAER----------------------------------------- --------DEVDSAIESQKDSE--------------------------------------------SNPSFAGTPGRRDS MPEGNPEHSVQHTKDG--LRDGDADED---------------DEVFEATRKESRERIMDRDTQGMLKSPVPFLLGHSLSK DGMDSFSKHFESIMESHRAKGTS-----YTSLDSIDILSSPARTH------GTFFTFDLPALTPE-VQGQIRD-SAKLIE ENFAPLAHLEPDSGTSSATDAPWTERE----------------------------------------------------- -------------------------------------EERGRRRKGARHSPCCSEDSFGTPLASNMSCS---EHPLSQLV SDSDSEMDSMEQLALGSTDT-----LS-NGHKA---DLEAAKRLAKRLYNLDGFKKA--DVARHLGKNNEFSKMVAGEYL KFFVFTGMSLDQALRS--FLKELALMGETQ-ERERVLAHFS-QRYYECNPNAISSE----DGAHTLTCALMLLNTDLHGH N---IGKRMSCSDFIGNLEGLNGGTDFP-------------KELLKALYGSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRKSLSELADP-KPKSIKRIS-------------------------------------SCSNPFLDF-SQDSSIATYKHG LLVRKIHADPDCKKT--------PRGKRGWKPFHAILKGMILYLQK---------------------------------- ------------------------EEYKPGKALAEEELKNAISIHHSLAVQAL-------------DYIKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAQNSEQMHSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKKFSRPLLPSSCTRLSQ---DEQVKSHETKFKTMSAELLEHRSSLP------------------- -----------------------------------------------DKKVKGKEYEELKQKEEYLEFEKSRYGTYAMLL R-------------------------------------------------------AKL-------KAGSEDLAAFESTL FDAA------GGEDDGLKKSRSSPSLNAEPSGTGTKVK-------RNVSERAGRQPPGH--PQKS--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Taeniopygia_guttata_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------PRQSSAHAQRIAKAKWEFF YGSSDTPKT-AEIPP--------TPASLCPSGP----------------------------------------------- GSCETGIIRRTVKYSETDLDTVPLRCYRETNIDDILAEK----------------------------------------- --------EEVDSAIESQKDSE--------------------------------------------SNPSFVGTPGRRNS TPDEPPAPATSCSKDG--LQNRDVDED---------------DEVFEAEGKQGKVRLY---TQGMLKSPVPFLLGHSLSK DGMDSFSKHFETIMESHRAKGTS-----YTSLDSIDILSSPARTH------GTFFTFDLPTLTPE-IQGKIRD-SAK--- -NFAPLAHLEPDSGTSSATDAPWTERE----------------------------------------------------- -------------------------------------EEQRKRRKGTRHSPCHSEDSFGTPLASNT--S---DRPQSQLV SDSESDMDSVEQLALGSTDT-----LS-NGHKA---DLEAAKRLAKRLYNLDGFKKA--DVARHLGKNNEFSRMVAGEYL KFFGFTGMSLDQALRT--FLKELALMGETQ-ERERVLAHFS-QRYYECNPNAISSE----DGAHTLTCALMLLNTDLHGH N---IGKRMSCSDFIGNLEGLNGGTDFP-------------KELLKALYGSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRKSLSELADP-NPKSIKRIS-------------------------------------SCSNPFLDF-SQDASIATYKHG LLVRKIHADPDCKKT--------PRGKRGWKPFHAILKGMILYLQK---------------------------------- ------------------------EEYKPGKALAEEELKNAISIHHSLATRAS-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAQNPEQMHSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKKFSRPLLPSSCTRLSQ---EEQVKNHETKFKTMSAELLEHRSSLP------------------- -----------------------------------------------EKKVKGKEYEELKQKEEYLEFEK--YGSYAQVG R--------------------------------------------------------VL-------KAGSEDMAAFESTL FDTG------GGEDDGLKKSRSSPSLNAEPSS------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Anolis_carolinensis_PSD -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------SPGSRTPLVAPISGGQSSVVTFRFIEKANVKTLNGLPLLGSSL----------------------- -------------------------------------------------------------------------------- ------------------------AISGSTDEQVPVAFTHSCKGKEHVGQKLKLETSASDPLLAGNRFLSGAQSSLSLGN GSPHPLNASSLSSSLTNGMSSP--------------SNDISLLRRGPQSGNSQYQGNSWTYSRESSAHAQRIAKAKWEFF YGSLDSPGT-GKVEI--------EMAPPSSTNP----------------------------------------------- GDCETGIIRRTLKYSETDLDSVPLRCYHETNIDDILAEK----------------------------------------- --------DEVDSAIESQKDSE--------------------------------------------SNPSFTGILGKGNT VPEDQLIQHTKEDENGKCLRNKILDIES--------------DDVFEVT-QQQHERIINREAHGLLKSPVPFLLGHSLSR DGMDSFSRHFESIMESHRAKGTS-----YTSLDSIDILSSPAHTHS-----GTYFTFDLPTLTPE-IQEQIRD-SAKLIE QNFAPLAPVEPDSGTSSATDAPWTERE----------------------------------------------------- -------------------------------------EEPRGGRKGVLQSPCHSEDSLGIPLASIL--S---EHPLSHLV SDSDSEMDSTEQLALGSTDT-----LS-NGHKA---DLEAAKRLAKRLYNLDGFKKA--DVARHLGKNNDFSKMVAGEYL KFFEFTGMSLDQALRS--FLKELALMGETQ-ERERVLAHFS-QRYYECNPKAISSE----DGAHTLTCALMLLNTDLHGH N---IGKRMSCSDFICNLEGLNEGSDFP-------------RELLKALYSSIKNEKLQWAIDE----------------- ------------------------------------------------------------------------------EE LRKSLSELADP-NPKSIKRIS-------------------------------------SCSNPFLDF-SQDPSIATYKYG ILVRKSHAEPDCKKT--------PRGKRGWKTFHGILKGMILYLQK---------------------------------- ------------------------EEYKPGKALAEEDLKNAISIHHSLATQAS-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPNIEQMHSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKKFSRPLLPSSITRLSQ---EEQVKNHETKFKAMAAELLEHRSSLP------------------- -----------------------------------------------EKKVKGKEYEELKQKEEYLIFEKSRYGVYATLM R-------------------------------------------------------AKL-------KTGSEDLAALEAAL FDAA------SSAEDNLKKSQSSHSVDQEPAGTGPRIK-------RNS-----RQATGN--LQKS--------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Danio_rerio_PSD_b MSQSGKILHLYVEVRSVPDEEGKDLGDVERTDSPMLAAPDIIQQSQIVGPNAPHGRVSPRGVLHKGGSSTQSLASCKSTS RHSVSFQLHPGLDSDQSTTQHQKNLPYDEISQLLSVLQTGTTGNKCHLVCSPSERDSFGREPHFSGRFTAPPTPSGTRKV CSPIKMKGGDEGRRSIATFSYIEKAKIKSVESQYSSLCQNEPQNPFKKNMEDRATSLHLKKRLSDPVWFNSFESMNNCNS KQLSQGLGNPHIGSPSFRRATLDVAREATHKALDEFGSPQLRQKLAGNCHDRGHDIRKVEQRRCRSWSGSPVIPSSSRTL PTKATIMDHERNSSFYRLPRSPATDQLSHHAKQAYFTISNSTVNTQEISNQRVQGSRLRPNLPSCKPTAIQHELPAKIVT QSPSNQQISHSMSDSPRQSHRVNFHLGNSKTKAEKVVNQLSEKRSISPATSPDTARKLAEEATKLSVLMEARRTPSPTPS STDTVRSDSPQRGHSREPQDSEAQSHSNCNLPAHEHNRKNFQTSVKTGYQFFQSTPLLSNIGSTSPAVPARLNRSDVKSS SPIRDPQIDRTQLVGKDSPTLHRHLPTQYTRDNHTPTYDGQLHDTLRGHKDSPDIIRRSFT------------------- -------------------------------------------------------------------------------- -------------RPNTDTSATWTSQEKHGLEECFTRDKKSLMEVNNQKRNSLNTPGSPDNHCGVSVPHSEIKGHNRAKK EWSGTASQSSSGVKGSLVESTL--------------HEKKHISSETSSRTSQKSSDSGNTAIQRPSLHSQKIARAKWEFL FGSHSEDQQTKDSSTPSSSGCSSESPTPIPPLSTHLRPVTTHSRHYKSIG------SSKSSCQDVQQVEVELISHHPTVG TSNKTGIIRRTVKYSETDIDAVPLRCYRETDLDEVMLAE----------------------------------------- -------QEEVDSAFGSNRSVL--------------------------------------------GTSGT--TSSSPLD GVLCPHTDGEEELQDEEVASWASVRMQGDKKRQ---NATPEGDEVFSRLLRGPLDYQPDS--HTDLKSPISVTSPCRVSS DCLDTFSRHFESIMESHRAKGTS-----YSSLDSED-ITPSGPPI---------FTFDFPTLTPEIQSQICES-AKQITE LNFASLTCPEPPTVSHLIVASQDLHREDR--------------------------------------------------- --------------------------------SSVCEEDGLFCTGSHSEQTHRPDS-------DSDA-----TKRERPSR PVSESDPEVAERLALGSTET-----LANGNK-A---DLQAAKRLAKRLYTLDGFKKS--DVARHLSKNNEFSHMVAEEYL SHFNFSGMMVDQALRV--FLKEFALMGETQ-ERERVLSHFS-KRYLQCNPKTIPYE----DSVHTLTCALMLLNTDLHGH N---VGKRMSCMQFIGNLQGLNDGQDFP-------------KDLLKALYNSIKNEKLQWTIDE----------------- ------------------------------------------------------------------------------EE LRKSFSEMDG--RKDSASHTMKRIS---------------------------------SGGNSLISV-AQQSSAQVYKNG FLVRKVHADPDGKKT--------PRGKRGWKTFYAILKGLILYLQK---------------------------------- ------------------------DEYRPDKQLSDEDLKNAVSIHHSLAMRAA-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPNAEQMQSWITRINTVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKKFSRPLLPGSNTKLSQ---EEQLKSHETRFRTVSAELQELRSTPQ------------------- -----------------------------------------------DRKTKSRDQEEYKQREEYLDFEKTRYGTYTMLL R-------------------------------------------------------TKI-------RMGETDLAAFEGRL FED-----------SGLQRTHSSPTLPQDISHASSTKE-------TSRSSSGSSRRTKRSDSQRHSFKQAAKQ------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Takifugu_rubripes_PSD_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------SLHCQRIARAKWEFL FGTPAED-----------GACRGEKELVTPPP--------------------------------------------AIIG TSPKTGIIRRTLKYSETDLDAVPLRCYRETDIDEVLLAE----------------------------------------- -------QDDADSAFGSNRSVQ--------------------------------------------GTSG---TGSSPLG GVADGGAAEGIQEASEEEEEEEEEEEE----------------MVSWASVRPTETFFDNH--HPALKSPLLVSGPR---C GAEDTFSRHFENIMESHRAKGTS-----YNSLDSEELLTSSTQTV---------LTFDLPTLTPTIHAP----------- LSFAPLAHDERPSLSDSIFTVTGDSDATR--------------------------------------------------- --------------------------------APSSER---LSSGSDDVPPGGHGR------AQLGS-----SWERARLA SDPEVD-----RLGLSSSDT-----LTNGSRHA---DVAAAKRLAKRLFNLDGFRKS--DVAPHLSKNNDFSRMVAEEYL SFFNFTGLSLDQALRT--LLGQFALMGETQ-ERERVLSHFS-KRYLSCNPRVIPSE----DAVHTLTCALMLLNTDLHGQ N---IGKRMSCAQFVGNLEGLNDGQDFH-------------KDLLKALYNSIKSQKLQWTLDE----------------- ------------------------------------------------------------------------------EE LRKSFSELGDSLCDSNASKSTKQVG---------------------------------SDEKPLPVG-SEPSGTLLYKNG FLVRKVHADSDGKRT--------PRGKRGWKTFYAILKGLILYLQK---------------------------------- ------------------------GEYRPDKQLSDEDLKNAVSIHHSLAMKAS-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVYLFQAPNAEQMQSWITRINTVSAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKKFSRPLLPGTMSKLSE---EEQVRSHEARFKALSTELAELRSYPP------------------- -----------------------------------------------DRKVKGRELEEYRLRDEYLEFEKTRYGTYAMLL R-------------------------------------------------------AKI-------QSGAEDLAAFESHL LDE-----------NGLQRCHSSPTL-HDSSQPSHFPR-------LRGLFTRASLLI-FPGALSGRRRV----------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Takifugu_rubripes_PSD_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------SSETLPSRSQRIARAKWEFL FG-GQNTP-------------FSPNP-SSPSSV-------------------------------------------HVKT TNQRTGIIRHTIKYSETDLDAVPLRCYRETDLDEVMRAEA---------------------------------------- -----EAGEDINTTFENNHSIR--------------------------------------------GYNSLKPGDAYQKP RMDGGKEG-----------KEEEGEEEV---------------ESDKDFFRTSE-ALSNA--QGGLKSPISIGSPRRPSE NHLDSFSRHFESIMESHRAKGTS-----YSSLDSVDLLTSGSTSV---------FTFDLPTYPPPPPPPPPPP-P-PLPP AAS---ALKFEETMKGRRRQREEEEEAGHL-------------------------------------------------- --------------------------------GSFWEGNAYLLPPQWEENTAADG----GRERPVN-------RPLELLY P-------QVEQLELGGSDD-----GLANGTKA---DLQAAKRLAKRLYNLEGFKKS--DVARHLSKNNEFSQMVVEEYL SNFDFTAMTIDQALRM--FLRKFALIGETQ-ERERVLAHFS-KRYRECNRESETNE----DSIHTLTCAVMLLNTDLHGN N---VGKRMSCSQFITNLEGLNDGHDFP-------------KDLLKTLYNSIKNEKLQWTIDE----------------- ------------------------------------------------------------------------------EE MK---SELTDTVRTDSASHTMKRLG---------------------------------SGGNPLVGVAQQVDG-ELYKSG FLVRKVHADPDGKRT--------PRGKRGWKSFYILLKGLVLYLQK---------------------------------- ------------------------DEYRAERELTEEDVKNAVSVHHSLAMRAA-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPNAEEMQSWITRINLVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKRFSRPLLPGSNTKLTQ---EEQAKSHENRFRSVCSELIDLTASTP------------------- -----------------------------------------------ERKVKGRELEEQKARQEYLEFEKTRYGTYAMLL R-------------------------------------------------------AKL-------LSGDEDLAAFEARL FSD-----------GGLQRAHSSPTLPQDS-SATKEKP-------SKKSKSMKVTSSSSSTSKSAGSGVQEG-------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Oryzias_latipes_PSD_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------GDTVSTLPSRSQKIARAKWEFL FGGKSEDSRCRK------EALPTTPPTSSPPSP-------------------------------------------PSSL SQGPACIIRRSIKYSETDLDAVPLRCYRETDLDEVMRAES---------------------------------------- -----EAPEEADSAFGSNRSVL--------------------------------------------ESSSFTPSNPSPKP HSVEREDGELG--QCEDAWRQAETESCQ---------------GGGGGFQSVAEGATSET--HGGLKSPISVGSPRRPSE SNLDSFSRHFESIMESHRAKGTS-----YSSLDSVDLLTSGSTSV---------FTFDLPTLTPEIQRCPAPK-LALMLQ ERTSEQAPRSTRAFQSGPSQRRRHGAAP---------------------------------------------------- --------------------------------SLKMASGKPALSPCSIVNREMLGRRVPGGERAVN-------RPVELLY PQ----DDVAQRLALGGSDE-----ALANGLKP---DLQAAKRLAKRLYNLDGFRKS--DVARHLGKNNEFSQLVAEEYL SCFNFKGLTIDQALRL--FLSHFALMGETQ-ERERVLAHFS-RRYKHCNPESLSTE----DSIHTLTCAIMLLNTDLHGN N---VGKRMSCTQFISNLEGLNDGKDFP-------------KELLKILYTSIKTEKLQWTIDE----------------- ------------------------------------------------------------------------------EE LRK-SISELAESRTDSASHTMKRLG---------------------------------SGGNPMVGVAQQADG-ELYMSG FLVRKVHADPDGKRT--------ARGKRGWKSFYAMLKGLVLYLQK---------------------------------- ------------------------DEYRTERELTEEDVKNAVSVHHSLAMRAV-------------DYSKRPNVFYLRTA D------------------------------------------------------------------------------- ------------WRVFLFQAPNAEQMQSWITRINVVAAM----------------------------------------- -------------------------------------------------------------------------------- --FSAPPFPAAIGSQKRFSRPLLPGSGTKLSQ---EEQAKFHENRFRAVSSELLELTPATP------------------- -----------------------------------------------DRKAKGRELEEQKLRKEYLEFEKTRYGTYAMLL R-------------------------------------------------------AKL-------SSGAEGLQAFESQL FDE-----------GGLQRAHSSPTLPQDAGNKEKTRG-------TKTSKSLKVTSSSRSEGGTGEGRRKN--------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Homo_sapiens_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------MEEDKLLSA---------------------------VPEEG DATR-DPGPEPEEEPGVRNGMAS-EGLNSSLCSPGHERRGTPADTEEPTKDPDVA------------------------- -------------------------------------------------------------------------------- ------------------------------FHGLSLGLSLTNGLALGPDLNILEDSAESRPWRAGVLAEGDNASRSLYPD AEDPQLGLDGPGEP----------------------------------------DVRDGFSATFEKILESELLRG-TQYS S------------------------------------------------------------------------------- ------------------LDSLDGLSLTDESDS----------------------------------------------- ---CVSFEAPLTPLIQQRARD----------------------------------------------------------- --------------SPEPGAGLGIGDMA---------------------------FEGDMGAAGG-DGELG-------SP LRRSISSSRSENVLSR------------LSLMAMPN-----------------GFHEDGPQGPG-----------GD-ED D-----DEEDTDKLLNSASDPS---------------------------------------------------------- -----------------------------------------LKDGLSDSD------------------------------ ----SELSSSEGLEPGSADP-----LANGCQG----VSEAAHRLARRLYHLEGFQR--CDVARQLGKNNEFSRLVAGEYL SFFDFSGLTLDGALRT--FLKAFPLMGETQ-ERERVLTHFS-RRYCQCNPDDSTSE----DGIHTLTCALMLLNTDLHGH N---IGKKMSCQQFIANLDQLNDGQDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------DE LRKSLSELVDDKFGT-GTKKVTRIL---------------------------------DGGNPFLDV-PQALSATTYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYRPDKALSEGDLKNAIRVHHALATRAS-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPAFPAAVSSMKKFCRPLLPSCTTRLCQ---EEQLRSHENKLRQLTAELAEHRCHPV------------------- -----------------------------------------------ERGIKSKEAEEYRLKEHYLTFEKSRYETYIHLL A-------------------------------------------------------MKI-------KVGSDDLERIEARL AT-------LEGDDPSLRKTHSSPALSQGH--VTG-----------SKTTKDATGPDT---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Gorilla_gorilla_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------MEEDKLLSA---------------------------VPEEG EATR-DPGPEPEEEPGVRHGMAS-EGLNSSLCSPGHERRGTPADTKEPTKDPDVA------------------------- -------------------------------------------------------------------------------- ------------------------------FHGLSLGLSLTNGLALGPDLNILEDSAESRPWRAGVLAEGDNASRSLCPD AEDPQLGLDGPGEP----------------------------------------DVRDGFSATFEKILESELLRG-TQYS S------------------------------------------------------------------------------- ------------------LDSLDGLSLTDESDS----------------------------------------------- ---CVSFEAPLTPLIQQRARD----------------------------------------------------------- --------------SPEPGAGLGIGDMA---------------------------FEGDMGAAGG-DGELG-------SP LRRSISSSRSENVLSR------------LSLMAMPN-----------------GFHEDGPQGPG-----------GD-ED D-----DEEDTDKLLNSASDPS---------------------------------------------------------- -----------------------------------------LKDGLSDSD------------------------------ ----SELSSSEGLEPGSADP-----LANGCQG----VSEAAHRLARRLYHLEGFQR--CDVARQLGKNNEFSRLVAGEYL SFFDFSGLTLDRALRT--FLKAFPLMGETQ-ERERVLTHFS-RRYCQCNPDESTSE----DGIHTLTCALMLLNTDLHGH N---IGKKMSCQQFIANLDQLNDGQDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------DE LRKSLSELVDDKFGT-GTKKVTRIL---------------------------------DGGNPFLDV-PQALSATTYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYRPDKALSEGDLKNAIRVHHALATRAS-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPAFPAAVSSMKKFCRPLLPSCTTRLCQ---EEQLRSHENKLRQLTAELAEHRCHPV------------------- -----------------------------------------------ERGIKSKEAEEYRLKEHYLTFEXSRYETYIHLL A-------------------------------------------------------VKI-------KVGSDDLERIEARL AT-------LEGDDPSLRKTHSSPALSQGH--VTG-----------SKTTKDATGPDT---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Mus_musculus_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------MDEEKLPCE---------------------------LHKEG SATQEDHGLEPEEEPGLQNGTAASEGLSSHISGPGGEKT--LEGTMEPVRGPDVA------------------------- -------------------------------------------------------------------------------- ------------------------------LPGLNL--SLTNGLALGQDGNILEDSIEFKTWRS-GPAEEEDVPGSPCPD AGDPQLGLDCPGEP----------------------------------------DVRDGFSATFEKILESELLRG-TQYS S------------------------------------------------------------------------------- ------------------LDSLDVLSLTDESDS----------------------------------------------- ---CVSFEAPLTPLIQQRARD----------------------------------------------------------- --------------SPEAGAGLGNGDMG---------------------------PEGDLGATGGCDGELG-------SP LRRSISSSRSENVLSH------------LSLTSVPN-----------------GFHEDGPGGSG-----------GDDED D-------EDTDKLLNSASDTS---------------------------------------------------------- -----------------------------------------LKDGLSDSD------------------------------ ----SELSSSEGLEPGSTDP-----LANGCQG----VSEAARRLARRLYHLEGFQR--CDVARQLGKNNEFSRLVAGEYL SFFDFSGLTLDRALRT--FLKAFPLMGETQ-ERERVLTHFS-RRYCQCNPDDSTSE----DGIHTLTCALMLLNTDLHGH VN--IGKKMSCQQFIANLDQLNDGQDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------DE LRKSLSELVDDKFGT-GTKKVTRIL---------------------------------DGGNPFLDV-PQALNATTYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYRLDKALSEGDLKNAIRVHHALATRAS-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPAFPAAVSSMKKFCRPLLPSCTTRLCQ---EEQLRSHENKLRQVTAELAEHRCHPL------------------- -----------------------------------------------ERGLKSKEAEEYRLKEHYLTFEKSRYETYIHLL A-------------------------------------------------------VKI-------KVGSDDLERIEARL AT-------IEGDDPALRKTHSSPALSLGHGPVTG-----------SKATKDTSASDT---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Bos_taurus_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------MDEDTLLST---------------------------LPGED GATW-DPSLEPEEEPGVQNGMASSEDLNSSHTSPGHAMRGPLAGTEGHTKGLDVA------------------------- -------------------------------------------------------------------------------- ------------------------------LHGLSLGLSLTNGLALGPDSNVLEHSTDPRPWRAGGLAEGDDASRSLCPD TEDPPLGPGGPGEP----------------------------------------DVRDGFSATFEKIVESELLRG-TQYS S------------------------------------------------------------------------------- ------------------LDSLDVLSLTDESDS----------------------------------------------- ---CVSFEAPLTPLIQQRARD----------------------------------------------------------- --------------SPELGAGLGTGDMG---------------------------SEGDMGAAGG-GGVLG-------SP LRRSISGSRSENVLSR------------LSLTAVPN-----------------GFHEDGPLGPR-----------GDEED DEEEEEEEEDTDKLLNSASDPS---------------------------------------------------------- -----------------------------------------LKDGLSDSD------------------------------ ----SELSSSEGLESGSTDP-----LANGGQG----VSEAARRLARRLYHLEGFQR--CDVARQLGKNNEFSRLVAGEYL SFFDFSGLTLDRALRN--FLXAFPLMGETQ-DRERVLTHFS-RRYCQCNPDDSTSE----DGIHTLTCALMLLNTDLHGH N---IGKKMSCQQFIANLDQLNDGQDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------DE LRKSLSELVDDKFGT-GTKKVTRIL---------------------------------DGSNPFLDV-PQALSATTYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYRPDKALSEGDLKNAIRVHHALATRAS-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPSFPAAVSSMKKFCRPLLPSCTTRLCQ---EEQLRSHENKLRQVTAELAEHKCHPV------------------- -----------------------------------------------ERGIKSKEAEENRLKEHYLTFEKSRYETYIHLL A-------------------------------------------------------VKI-------KVGSDDLERIEARL AT-------LEGDDPSLRKTHSSPALSQGHGTVTG-----------SKAMRDTTGPDT---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Monodelphis_domestica_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------MDDENLSTSPSVEGSASHSLILGLQPNREQP---------------------------LREES TDDQLFPSDGAKGDRSLDGEHVVSSGDTCLTEPPEHWKRTDTLACGNSAEGRDGD------------------------- -------------------------------------------------------------------------------- ------------------------------LCDLSHMNSESLEFGSGQMMDLDDAEASHMSGCSDYWREKELEKGEIPSR KFGYQQPLSSAPGYPCPEVRLF--------------EEPEASESQDDGEPSPFKDIRDGFSSTFEKIVESELMKG-TYYS S------------------------------------------------------------------------------- ------------------LDSLDVLSLTDETDS----------------------------------------------- ---CVSLEVPLTPLIQQRVKE----------------------------------------------------------- --------------SPEPT--EVRPEDRDGE-------------------GEEAIDGQDGAEAGLVDGDFG-------SP LRHSITSSRSENVLSR------------LSLKVVPN-----------------GYHANTTQDPE-----------EEEEE E------GDDTTKLINSVSDPS---------------------------------------------------------- -----------------------------------------LKDALSDSD------------------------------ ----SDLGSTEQLDHGSTDT-----LANGCQA----VNEAAKRLARRLYHLEGFKR--CDIARQLSKNNEFSRLVAEEYL SFFDFSGLSLDRALRT--FLKAFPLMGETQ-ERERVLTHFS-RRYRQCNQEESTSE----DGIHTLTCALMLLNTDLHGH VN--IGKKMSCQQFIANLDGLNDGQDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------EE LRKSLSELVDDKFGP-GAKKVTRII---------------------------------DGSNPFLDI-PQALNAATYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYKPDKDLSEVDLKNAIRVHHALATRAL-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPAFPAAICSMKKFCRPLLPSSTTRLCQ---EEQLRSHENKMRQIMAELTEHRMHLA------------------- -----------------------------------------------EKNVKSKEAEEYRLKEHYLTFEKSRYETYIHLL C-------------------------------------------------------VKI-------EVGSDDLEQIEARL AT-------AEAEDLSLRKTHSSPSLSQGHGSTSG-----------GLVQRDVTEPST---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Gallus_gallus_PSD2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------MSESRHFPLSVAARSELHSSGSQPTVQAHSDGDEQLG---------------------------QPAEP ASGRASPLDDAEPSPSADEEHHGDQHLAASTGEWEQEVHATSNSEGCKELALTNG------------------------- -------------------------------------------------------------------------------- ------------------------------VDVELGAGGEEVRLQPPDGSVPSPGSVDSGEEGSPGPQARSQALSKVLLH GFLGSAGALSADEPEEQLGFAA--------------GDAKLSCSEDDKEHFQFKDIRDGFSSTFEKIVESDLMKG-TYYS S------------------------------------------------------------------------------- ------------------LDSLDVLSLTDETDS----------------------------------------------- ---CVSFEAPLTPLIQQRVKE----------------------------------------------------------- --------------SPELLEQKLVAQQRESP-------------------HHMVADKQEQAAAKPAEVDFG-------SP LRHSITSSRSENVLSR------------LSLKNIPN-----------------GFHVEGSEE------------------ ---------DATKIINSISDAS---------------------------------------------------------- -----------------------------------------LKDALSDSD------------------------------ ----SDMGSTEQLDQGSTDT-----LANGCRA----DSEAAKRLAKRLYNLEGFKR--CDVARQLGKNNEFSKLVAEEYL SFFDFTGLTLDKALRT--FLKAFPLMGETQ-ERERVLIHFS-RRYCQCNPEESTSE----DGVHTLTCALMLLNTDLHGH -N--IGKKMSCQQFITNLDGLNDGKDFA-------------KDLLKTLYNSIKNEKLEWAIDE----------------- ------------------------------------------------------------------------------DE LRKSLSELVDDKFGA-SAKKVTRIV---------------------------------DSSNPFLDI-PQALNAVTYKHG VLTRKTHADMDGKRT--------PRGRRGWKKFYAVLKGTILYLQK---------------------------------- ------------------------DEYKPDKDLSEVDLKNAIRVHHALATKAS-------------DYSKKSNVLKLKTA D------------------------------------------------------------------------------- ------------WRVFLFQAPSKEEMLSWILRINLVAAI----------------------------------------- -------------------------------------------------------------------------------- --FSAPAFPAAICSMKKFCRPLLPSSMTKLCQ---EEQLRSHENKMKQIADELAEHKSHPV------------------- -----------------------------------------------EKSLKSKEAEEYRLKEHYLIFEKSRYETYINLL C-------------------------------------------------------MKI-------KVGTDDLERIETSF FK-------VEADDIALRKTHSSPSLSQGHMSVSC------------KVEKDIIEQNT---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------- >Danio_rerio_PSD2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- MSQEGQDDPLHTPAETPEGQEEHLENCNGTETETEEPDDGDTENNRNT---------------------------EEEEE EEEEKVTLDQDDGRNGEIESSCLDPGTENGDICEGGDTQRAEKDSSVTICSLRFE------------------------- -------------------------------------------------------------------------------- ------------------------------NGTEDDSEEQDDEEVIPHEGNLDAFSSTFELSVEEADAEVEDEEREETET RNQDSFSSTFESIVERVAKATV--------------VEEEEEEEEGEEEFDRTKESQDGFSSTFERIVESELLRGGTCYS S------------------------------------------------------------------------------- ------------------LDSLDVLSLTDETDS----------------------------------------------- ---CVSFEAPLTPLIQQRALM----------------------------------------------------------- --------------GPEP---PELELETVQE-------------------GAEGEGEFGTETARDEASS--------ASP LRTTIPGSRSENVLSQ------------PAQWSIPN-----------------GFHIELPGNGQ-----------SA--- -----------GMMPNSISDAN---------------------------------------------------------- -----------------------------------------LTDVLCDSD------------------------------ ----SELGSVDTLERGSTDT-----LANGCRV----DADAAKRLAKRLFYLEGFKR--CDVARHLGKNNEFSQLVASEYL SFFDFTGLSLDRALRN--FLKAFPLMGETQ-ERERVLVHFS-KRFCHCNPETLTSE----DGAHTLTCALMLLNTDLHGH N---IGKKMSCQQFISNLDGLDDGKDFP-------------KELLKVLYNSIKNEKLEWAIEE----------------- ---------------