>Homo_sapiens_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPAFHLARP-ADP-REPLENSA--------------SESSDTELPE---------------------- -KERGGEPKGPEDSGAGG---------------------------------------------------TGCG-GADDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Mus_musculus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPSFHLARA-ADP-REPLENSA--------------SESSDADLPD---------------------- -KERGGEAKGPEDGGAGS---------------------------------------------------AGCGGGAEDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Pan_troglodytes_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPAFHLARP-ADP-REPLENSA--------------SESSDTELPE---------------------- -KERGGEPKGPEDSGAGG---------------------------------------------------TGCG-GADDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Macaca_mulatta_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPAFHLARP-ADH-REQLENSA--------------SESSDTELPE---------------------- -KERGGESKGPEDSGTGG---------------------------------------------------TGCG-SADDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYTVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Rattus_norvegicus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPSFHLART-ADP-REPLENSA--------------SESSDADLPD---------------------- -KERGGEAKVPEDGGAGS---------------------------------------------------AGCG-SAEDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAAGYSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGSVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Canis_familiaris_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLR-PPPPPHDMGPAFHLARA-ADP-REPLENSA--------------SESSDTELPE---------------------- -KERGGEVKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Bos_taurus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPQPHDMGPAFHLART-ADP-REPLENSA--------------SESSDTELPE---------------------- -KERGGEPKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYDD-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Pteropus_vampyrus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDAFKGG----------------------------MSLERLP-------------E GLRPPPPPPHDMGPAFHLARA-ADP-REPLENSA--------------SESSDTELPE---------------------- -KERSGESKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG YVPQFSGLVQPYED-VYAAG-YNYN-WATKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYGG---LQGP--AS---GLNACQYN---S----- >Monodelphis_domestica_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDSFKG----------------------------GMGLERLP-------------E GLRPPPP--HDMSSSFHLARA-SDS-REPLENSA--------------SESSDTEVPE---------------------- -KERSGETKGNEDGGG------------------------------------------------------------EDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG YVPQFSGLVQPYED-VYAG--YTYNNWAAKSLTPAPLSTKGFTF-FN---SM--SPLSSQSMFSA-PSTISS-MSMPSGM GHSAVPGMPN-SSLNNINNLNNLTGSS--LNSAMSS------SACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK QHSTF----GYSS---LQSP--GS---GLNACQYN---S----- >Gallus_gallus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDSFKG----------------------------GMNLERLP-------------E SLRPQPS--HDMASSFHLQRS-SEP-RDPIENSA--------------SESSDTEVPER------------KRGK-ENLT KREGGGGNAA-ADGAA------------------------------------------------------------DDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG YVPQFSGLMQPYDD-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MNMPSGM GHSAVPGMAN-SGLNNIN---NISGSS--LNSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYSS---LQSP--GS---SLNACQYN---S----- >Taeniopygia_guttata_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDSFKG----------------------------GMNLERLP-------------E SLRPQPS--HDMASSFHLQRS-SEP-RDPIDNSA--------------SESSDTEVPEP------------ERQRGAKAG KKERSGEQKN-EDGAA------------------------------------------------------------DDPA KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG YVPQFSGLMQPYDD-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSIPS-MNMPSSM GHSAVPGMAN-SGLNNIN---NISGSS--LNSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK QHSSF----GYSS---LQSP--GS---SLNACQYN---S----- >Xenopus_tropicalis_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDSFKG----------------------------AMNLERLP-------------E SLRPQPS--HDMATSFHLQRS-SEA-RDPMDNSA--------------SESSDTEIAE---------------------- -KERSGEPKG-EDGNG------------------------------------------------------------DDPT KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNG YVPQFSGLMQPYDE-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSG-PSSISS-MSMPSSM GHSAVPGMPN-SSLNNINNLNNISSSS--LNSAMSS------TACPYGP--PGSPYTVYR-----DTCNSSLASLRLKSK QHSTF----GYSS---LQSP--AS---SLNACQYN---S----- >Danio_rerio_PITX1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------MNVD----------------- -----------MASSFHLPRS-ASSTRETLENTS--------------SESSDTEAAE---------------------- -KERSVEQRS-DDGNA------------------------------------------------------------DDP- KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS YLPQFSGLMQPYDD-VYPT--YTYNNWTNKGLTPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PSSISS-MSMASGM GHSAVPGMPT-TGLNNIGNLNGIGGST--INPAMSS------STCPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK QHPSF----GYSG---LQSP--GS---SLNACQYN---S----- >Takifugu_rubripes_PITX1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------------------------------HSDN WFVFSCFAGNVMSCKPNSEEAGMELNLSKNGISCVDPG--------------------GMNLDRIA-------------E AARAPPP--RDVAPAFHLPRT-SNSSRDTLENSS--------------SESSDTDLAE---------------------- -KERSAEQRS-DDGNA------------------------------------------------------------DDP- KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS YLPQFSGLMQPYED-MYPA--YTYNNWTNKGLTPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PSSISS-MTMASGM GPSAVPGMPT-PGLNNISNLNGIGTSG--INSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK QHPTF----GYSG---LQSP--GT---SLNACQYN---S----- >Tetraodon_nigroviridis_PITX1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MELNLSKNGISCVDPGS-------------------GMNLDRIA-------------E AARAPPP--RDGAPAFHLPRS-SNSRRETLENSS--------------SESSDTDLAE---------------------- -KERSAEQRS-DDGAA------------------------------------------------------------DDP- KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS YLPQFSGLMQPYDD-MYPA--YTYNNWTNKGLAPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PNSISS-MTMASGM GPSAVPGMPA-PGLNNISNLNGIGTSG--INSAMSS------PACPY-P--PGSPYSVYR-----DTCNSSLATLRLKSK QHPTF----GYSG---LQSP--GS---GLNACQYN---S----- >Oryzias_latipes_PITX1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------MNLDRIA-------------E AARAPPPT-RDVAAAFHLQKS-SNSSRETLENSS--------------SESSDAELAE---------------------- -KERGAEHRS-DDGNA------------------------------------------------------------DDP- KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS YLPQFSGLMQPYDD-MYPA--YTYNNWTNKGLAPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PNSISS-MTMASGM GHSAVPGMPT-PGLNNISNLNGIGTSG--INSAMSS------SACPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK QHPTF----GYSG---LQSP--GS---SLNACQYN---S----- >Branchiostoma_floridae_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MDTLNDS----------------------LSLEQLVSVSPRRSQLTMAGMAPINNS GTSTGSALDSTAVAGAHTSMAGTDSSMDSTHGSGA-----------ATVSAGSPVGKD---------------------- --SGSGSTPSTQDVTQD----------------------------------------------------------DDEMR KRRRQRRQRTHFTSQQLQELEASFARNRYPDMATREEIAAWTNLTEARVRVWFKNRRAKWRKRERNQL-----GEF-KNG FGPHFNGLMQPFDDGLYSGYSPAYNNWAA--KVPSPLTAKSFPWGLNSSGVPNVNPLSSQAMCFT-PPTTIG----TATT MVPSMN-VGN--GLNSLSSLQNPTVA-----------------PCPYAS--PGQP-YAYR-----EQCNSSIAALRLKAK QHSTS----VASS---FSYPSPVRQ-QTLSACQYA---VDRPV- >Strongylocentrotus_purpuratus_PITX1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNQLHHGPL--------------------STLEDLVASESAR-------------- ---------VSAGIGSVAAQRPIDSAPQSRSSHHV-----------HSPTIDHNQDKP---------------------- --GVKGGHDDGDDSDND----------------------------------------------------------QDN-G KKKRTRRQRTHFTSQQLQELEANFSRNRYPDLSTREEICAWCNLTETRVRVWFKNRRAKWRKRERNQL-----HEL-KNG LGAGFNGLMQPFDDGLYSGYS--YNNWAAA-KTANHLGTKSFAWSLN---TVNPLSMTSQQMCFNPPPTTLS----STFS AATPVNGVGQ--QLNSFNNAAAAAAVGA--------------ASYPYGSP-PGAPPYMYR-----EPCSNSIASLRLKAK QHHSS----NVPG---LSYPVRQ-S-PTLSACQYAG--LNGSTT >Homo_sapiens_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSS-------- CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKSQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Mus_musculus_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LPLE-------------HRAAG-TKLSAASSP-F------- CHHPQA-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEVAE---------------------- -KDKGQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Pan_troglodytes_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSS-------- CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKSQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Macaca_mulatta_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSSS------- CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKGQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Rattus_norvegicus_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LPLE-------------HRAAG-TKLSAASSP-F------- CHHTQA-LAMASVLAPGQPRS-LDASKHRLEVHT-------------ISDTSSPEVAE---------------------- -KDKGQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Oryctolagus_cuniculus_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAASSSSS------- CHHPPP-TAMASVLAPGQPRS-LDASKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKSQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Canis_familiaris_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAVG-TKLLATASPSS------- CHHPQP-LAMASVLAPGQTRS-LDSAKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKSQQGKN-EDVGT------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Bos_taurus_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKGP--------LHLE-------------HRAAG-TKLLAASSSSS------- CHHPQP-LAMASVLAPGQARS-LDSSKHRLEVHT-------------ISDTPSPEAAE---------------------- -KDKSQQGKN-EDVGA------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Gallus_gallus_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MSCMKDP--------LSLE-------------RLGAGNNKLCSSSPSSSSSSSS-- CHHQQPALAMATALAPGQARSSLEAAKHRLEVHT-------------ISDTSSPEAAE---------------------- -KEKSQQGKS-EDAGP------------------------------------------------------------EDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SGLNSLNNLNNLSNPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Taeniopygia_guttata_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNCMKDP--------LSLE-------------RLGAG-NKLCSSSPSSSSSSSSSS CHHHQPALVMATALAPGQARSSLESAKHRLEVHT-------------ISDTSSPEAAE---------------------- -KDKSQQSKN-EDAGP------------------------------------------------------------EDP- KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Xenopus_tropicalis_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNSMKEP--------LHLDHLVGSKLATASSHHQHHHQHHQQH------------- -QQPQA-VTLVSMASSLGQRS--GECKARLEVHT-------------ISDTSSPEAAD---------------------- -KDKSHQSKN-EDSST------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPS--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSS-PNSISS-MSMSSGM VPSAVTGVPG-SGLNSLNNLNNLSNPS--LNTAVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--GS---NLSACQYA---VDRPV- >Danio_rerio_PITX2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MTSMKDP--------LSLD-------------HHHHN-HHVTG------------- -SKHAP-LSMASSLQPL-QRS--VDSKHRLDVHT-------------VSDTSSPESVE---------------------- -KEK-GQSKN-EDSN-------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-PNSISS-MSMSSSM VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV- >Takifugu_rubripes_PITX2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNSMREP--------LNID-------------HHHLTGNKLTS------------- -THHTA-LTMASSLQPL-QRS--VDAKHRVEVHT-------------VSDTSSPESVE---------------------- -KEK-IQNKN-DDSS-------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTPASLSTKSFPF-FN---SMNVNPLSSQTMFSPAPNSIS---SMTSGM VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV- >Tetraodon_nigroviridis_PITX2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNSMREP--------LNID-------------HHHLTGNKLTS------------- -THHTA-LTMASTLQPL-QRS--ADAKHRLEVHA-------------VSDTSSPESVE---------------------- -KEK-IQNKN-DDSS-------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTPASLSTKSFPF-FN---SMNVNPLSSQTMFSPAPNSIS---SMTSGM VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV- >Gasterosteus_aculeatus_PITX2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNSMRDP--------LNID-------------HHHVTGNKLAS------------- -AHPTA-LAMASTLQPL-QRS--VDSKHRLEVHT-------------VSDTSSPESVE---------------------- -KEK-NLNKN-DDSS-------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-SNSIS---SMTSSM VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV- >Oryzias_latipes_PITX2a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MNSMRNP--------LNTEQPH----------HLHLPGNKLTS------------- -PQHTA-LAMASSLQPL-QRS--ADSKHRLEVQA-------------VSDTSSPESVE---------------------- -KEK-IQNKN-DDSS-------------------------------------------------------------DDPS KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGPQFNGLMQPYDD-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-PNSIS---SMTSSM VPAAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV- >Homo_sapiens_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV- >Mus_musculus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV- >Pan_troglodytes_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV- >Macaca_mulatta_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS--AAAAAAA--ASSPY-VYR-----DPCN-SLASLRLKAK QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV- >Rattus_norvegicus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YTYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV- >Oryctolagus_cuniculus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV- >Canis_familiaris_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDWEKAW---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRGQRTHFTSQQLQELEAPFQRNRYPDMSTREEIAVWTNLTEARVGVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV- >Bos_taurus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS---------------------- --------VSLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIS--ASMVPSG AT-APGTVPGHGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPT---VPGPPPAA---NLSPCQYA---VERPV- >Pteropus_vampyrus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS---------------------- --------ASLPGGSP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LTAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA AA-SPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPT---VPGPTPAA---NLSPCQYA---VERPV- >Monodelphis_domestica_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFALLSEAEARSPALSLSDAGTPHPPHPEHSC-----------KGQEHSDTEKAP---------------------- --------PQLPGGSPT-----------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTTLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FGASLGGLVPPYEE-LYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PGSIATAASMVPTA AAGAAGAVAGPGGLQGLGGGPAGLAPAAVSSGAVSCPYAT--AAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK QHASF----SYTA---VPGPAPAA---NLSPCQYA---VERPV- >Ornithorhynchus_anatinus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLSEAEARSPALSLSDAGTPHP---EHGC-----------KGPEHSGPPPPV---------------------- --------AGLPTPGL------------------------------------------------------------GXXX XKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG FGAQFSGLVPPYEE-MYPG--YSYGNWAPKGLAAA-PGAQELPF-FN---SVNVSPLASQPMFSP-PSSIA----SVPMP AS--MASLQNLGGLQNLGGGP-GLAP-AVPSGAGSCPYASAAAAAAAAA--AAAPY-VYR-----DPCNSSLASLRLKAK QHASF----SYPA---VPNAASAAG-ANLSPCQYA---VERPV- >Gallus_gallus_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLADAEARSPALSLSDSGTPQHEHSCKG--------------QDHSDTEKSQ---------------------- -------QNQTDDSNP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS FGAQFNGLMQPYDD-MYSS--YSYNNWATKGLATSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSIAS-MTMPSSM VPSAVTGVPA-SSLNNLGNINNLNSPS--LNSAVSS------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK QHANF----TYPA---VQTA--AS---NLSPCQYA---VDRPV- >Taeniopygia_guttata_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLADTEARSPALSLSDSGTPQHEHSCKG--------------QDHSDTEKSQ---------------------- -------QNQTDDSNP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS FGAQFNGLMQPYDD-MYSS--YSYNNWATKGLASSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSITS-MTMPSSM VPTAVTGVPA-PSLNNLGNINNLNSPS--LNSAVSS------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK QHANF----TYPA---VQTA--AS---NLSPCQYA---VDRPV- >Anolis_carolinensis_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MEFNLLTDSEAHSPTLSLSESGTPQHEHSCKG--------------QEHSDTEKSQ---------------------- -------QNQTDDSNP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS FGAQFNGLMQPYDE-MYGG--YSYNNWATKGLAASTLSAKSFPF-FN---SMNVNPLSSQPMFST-PSSIGS-MPMPSSM VPTTVTGVPG-PGLN------NLNSPG--LSSAVSS------STCPYAS--SASPY-MYR-----DTCNSSLASLRLKAK QHANF----TYPA---VQTA--SS---SLSPCQYA---VDRPV- >Xenopus_tropicalis_PITX3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLTDSEARSPALSLSDSGTPQHDHSCKG--------------QEHSDTEKSQ---------------------- -------QNQTDDSNP------------------------------------------------------------EDGT LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS FGAQFNGLMQPYDD-MYSG--YSYNNWATKGLATSPLSAKSFPF-FN---SMNVSPLSSQPIFSP-PNSIAS-MTMPSSM VPSAVTGVPG-SSLNNLGNINNLNSPS--LNSAVSA------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK QHANF----TYPA---VQTP--AS---NLSPCQYA---VDRPV- >Danio_rerio_PITX3a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLTDSEARSPALSLSDSGTPQHDPGCKG--------------QDNSDTEKSH---------------------- -------QNHTDESNP------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGAQFNGLMQPYDD-MYSG--YSYNNWATKSLASSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSIPS-MNMASSM VPSAVAGVPG-SGLNNLGNLNNLNSPT-LNSAAVSA------AACPYAT--TAGPY-MYR-----DTCNSSLASLRLKAK QHANF----AYPA---VQNP--VS---NLSPCQYA---VDRPV- >Tetraodon_nigroviridis_PITX3a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------ADTEKSQ---------------------- -------QNQLDESSA------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGAQFNGLMQPYDD-VYSG--YSYNNWAAKGLASSPLSAKSFPF-FN---SMNVSPLSSQSMFSP-PSSLPS-MNMASSM VPSAVAGVPA-AGLNNLGNLNNLNAPTALNSVAVSA------ATCPYAP--SAGPY-MYR-----DTCNSSLASLRLKAK QHANF----SYPA---VQNP--VA---NLSPCQYA---VDRPV- >Oryzias_latipes_PITX3a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --MDFNLLTDSGTRSPALSLSDAGTPQHDAGCKG--------------QDNSDTEKSH---------------------- -------QNQLDESSA------------------------------------------------------------EDGS LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG FGAQFNGLMQPYDD-MYTG--YSYNNWATKSLASSPLSTKSFPF-FN---SMNVSPLSTQPMFSP-PSSIPS-MNMASSM VPSAVAGVPA-AGLNNLGNLNNLNSPTALNSVAVTA------ATCPYAT--TASPY-MYR-----DTCNSSLASLRLKAK QHTNF----AYPT---VQNP--VS---NLSPCQYA---VDRPV-