>Homo_sapiens_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY SKSNGRGGSQAGGSGSAGQYGSDQQHHL-------GSGSGAG-----------------------------------GTG G--PA-----GQAGRGG----AAGTAGVGETGSG----------DQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gorilla_gorilla_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY SKSNGRGGSQAAGSGSAGQYGSDQQHHL-------GSGSGAA-----------------------------------GTG G--PA-----GQAGRGG----AAGTAGVGETGSG----------DQAGGEGKHITVFKTYISPWERAMGVDPQQKVELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Mus_musculus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKRRKSSKLIMELT----- --------------------GGGRESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLETAGQG---------------FSY GK--GSSGGQAGSSGSAGQYGSDR-HQQ-------GSGFGAG-----------------------------------GSG G--PG-----GQAGGGG----APGTVGLGEPGSG----------DQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEHVDYNVDV- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Rattus_norvegicus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKRRKSSKLIMELT----- --------------------GGGRESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLESAGQG---------------FSY GK--GSSGGQAGASGSAGQYGSDR-HQQ-------GSGFGAG-----------------------------------GAG G--PG-----GQAGGGA----APGTVGVGEPGSG----------DQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEHVDYSVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Oryctolagus_cuniculus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------VSY SK--GSGGGQAGGSGSAGQYGSDHQHHH-------GSGSGAG-----------------------------------GAG G--PG-----GQAGKGG----AAGAGGVGETGSGK---------NQTGGDGKHITVFKTYISPWERAMGVDPQQKVELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEHADYHVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Canis_familiaris_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGRESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY SK--GSSGGQAGGSGSATHHGSDQHHHQ-------GSGSGSG-----------------------------------GTG G--PG-----GQTGKGG----AAGTAGVGETGTG----------DQTGGEGKHITVFKTYISPWERAMGVDSQQKVELGI DLLAYGAKPELPQYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQSLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Equus_caballus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY SK--GSGRGQAGGSGSAGQYGSDQQHHQ-------GPESQSG-----------------------------------GTG G--PG-----GQTGRGG----VAGTAGVGETGTGK---------YQAGGEGKHITVFKTYISPWERAMGVDPQQKVELGI DLLAYGAKAELPQYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Loxodonta_africana_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELS----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSIDHFQKFLPTVGGQLGTAGQE---------------FSY GK--GSGGGQAGGSSSARQYGSDQQHHR-------GPGSASGSGTG---------------GTGG----------PGGTG G--PG-----GQASRGGGSSAGGGSVGVGESGTG----------DQAGGEGKHITVFKTYISPWERAMGVDAQQKVELGI DLLAYGAKAELPKYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKIELGPLLSEPLVLYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- SIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Myotis_lucifugus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY GK--GSSGGEAMGSGSAGQHGSDQQHHQ-------GPGSGSG-----------------------------------GAG G--PG-----AQTGRGG----AAGTAGVGDTGTG----------DQAGGEGKHITVFKTYISPWERAMGVDPQQKVELGI DLLAYGAKAELPQYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQSLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Pteropus_vampyrus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKKRKSSKLIMELT----- --------------------GGGQESSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENHPDVF------------------------------- -------------------------------------SDSSMDHFQKFLPTVGGQLGTAGQG---------------FSY SK--GSGGGQARASGSAGQYGSDQQHHQ-------GPGSGSG-----------------------------------GTG G--PG-----GQTGRGG----TTGTAGVGDTGTG----------DQAGGEGKHITVFKTYISPWEKAMGVDPQQKVELGI DLLAYGAKAELPQYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLILYNQNLS NRPSFNRTPIP--------------------------------WLSS----------------------GEPVDYNVDI- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Monodelphis_domestica_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKRRKPSKLIMELT----- --------------------GGGQDSSGLNLGKKI-----------------------------------SVPRDVMLEE LSLLTNRGSK------------------MFKLRQLRVEKFIYENNPDVF------------------------------- -------------------------------------SDNSMDRFQKFLPTVGGQLGTDGQG---------------FSY GG--GSSRGQMGSSSSAGQHGSTQHQHHQ------GSGPGSG-----------------------------------GIG G--PG-----SQAGGGG-----DGRGGDGSAGTG----------DHAGGEGKHVTVFKTYISPWERAMGVDPQQKVELGI DLLAYGAKADLPHYKSFNR---------------------TAMPYGGYEKASKRMTFQMPKLDLGPLLSEPLVLYSNSLS NRPSFNRTPVP--------------------------------WLSS----------------------GEPVDYSVDV- GIP------LDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Ornithorhynchus_anatinus_MYOZ1 -------------------------------------------------------------------------------- --------------------------------------------------MMPLSGTPAP-NKRKKSTKIIMELN----- -------------------RDGGQEGSRLNLGKKI-----------------------------------SIPRDVMLEE LSLLTNRGSK------------------MFKLRKKRVEKFIYENNPDVF------------------------------- -------------------------------------TDSSLDHFQKFIPTMGGQLGGDGRQ---------G-----FSY DS------GRMVGGVSAGQYGSDQQQQNLH-----GHSATQG-----------------------------------GHR G--SG-----GKSG----------DG-QG-DGTGS---------SSVPGTGK---------------------------- -------------------------------------------PQG---------------------------------- ------RQ------------------------------------------------------------------------ ---------VVGEGSEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gallus_gallus_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLAGTPAP-LKRKKPTKLIGKLT----- H------------------EVMPQEVTKLNLGKKI-----------------------------------SIPRDVMLEE LSLLTNKGSK------------------MFKLRQLRVEKFIYENNPDAF------------------------------- -------------------------------------TDNSVDHFQKFIP-PGGHYGEDAHG---------------YGH --------GRMVGGVTAGHHGSSKQHYSTVPP-RPGSKGGPG-----------------------------------DSE GEHAE-----LSAGTAG--EGG--------HGTEK---------DGKSG-GKKP-LVKTYISPWERAMGISPEDKSQLTI DLLSYSPKADFPHYKSFNR---------------------TAMPYGGYEKAAKRMTFKVPQFDICPLLPESLVLYNQNFR NRPSFNRTPIP--------------------------------WMPS----------------------GESSEYHTDI- NVP------RSGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Taeniopygia_guttata_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLAGTPAP-VKRKKSTKLIGKLT----- H------------------EAMPQEVSKLNLGKKI-----------------------------------SIPRDVMLEE LSLLTNKGSK------------------MFKLRQLRVEKFIYENNPDAF------------------------------- -------------------------------------TDNSVDHFQKFIP-AGGSYGEDAHG---------------YAH --------GRMVGGMPAGQHGSSTQQHPGVPP-RPGSRGGAR-----------------------------------DGE GEQAG-----KSSGSGG--EGARTDIGVTESGNKA---------DGKSG-GKKVTIFKTYISPWERAMGISPEDKSQFST DLLSYSPKADFPHYKSFNR---------------------TAMPYGGFEKAAKRMTFKVPQFDICPLLPESLMIYNQNFS KRPSFNRTPIP--------------------------------WMPS----------------------GDFSEYQTAV- NVP------MTGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Anolis_carolinensis_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLAGTPAP-HKKRKPTKLILELT----- Q------------------EVMPQEGSKLNLGKKI-----------------------------------SIPRDVMLEE LSLLTNRGSK------------------MFKLRQMRVEKFIYENNPDMF------------------------------- -------------------------------------IDNSVDHFQKYIP-TGGQYGIDSHG---------------YSQ S------GGRMVSGVTVGPYGSIKLQYPPAPPPKPGSKGGAG-----------------------------------GTG SGGTGTGQTEGSANAGGGVDGGGSE--TTG--GQG---------DNKSGSGKHVSIFKTYISPWERALGLTPQEKSSINI DFLFCGPKTDLCHYKSFNR---------------------TAMPYGGYDKAAKLMTFQMPEFDVGPAVPEPVVVINQEVT NRPSFNRTPVP--------------------------------WLGS----------------------GEPAEYTIEV- NVP------VAGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Pelodiscus_sinensis_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLAGTPAP-IKTKKSTKLIGKLT----- R------------------EVMPQEGSKLNLGKKI-----------------------------------SIPRDVMLEE LSLLTNKGSK------------------MFKLRQLRVEKFIYENHPDVF------------------------------- -------------------------------------TDSSVDHFQKFIP-VGGHYGGEAHG---------------YLH S------GGRMVGGVTAGQYGSSKLHYPPAPPPKPGSKGGAG-----------------------------------GTE ADHVG-----GSAGSGGGVDGGGSN--DAGKGDQA---------GEKSGGGKKVSIFKTYISPWERALGISPQEKSQFTI DLLSCGSKSDLPHYKSFNR---------------------SAMPYGGYEKARKLMTFQMPEFDVGPLVPEPIIVYNQDIN TRPSFNRTPIP--------------------------------WQGS----------------------GEPTEYNIEI- KVP------MDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Xenopus_tropicalis_MYOZ1 -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAP-NKRKKSTKIIMEINP---- S------------------REGEIEISKLNLGKKI-----------------------------------SVPRDIMLEE LSLLSNKGSK------------------MFKLRQKRVEKFIYENNPDVF------------------------------- -------------------------------------SDNSLDHFQKFIPTVGGQLGAKGQSGVGVGGY--G-----LLY GS------GQMLSSISGGRHGSGGQQPPVPPP-KPGSKSAPG-----------------------------------GQS G--TG-----GSGGKDS----GVVDGSQGKEGQSG---------QQDGGSGKQITVFKTYLSPWDKAMGIDPKQPTHFTV NLLEYGKKAELCKYKSFNR---------------------SAMPFGGYEKASKLMTFQMPDFDAPPPEPEPVVVINQDIT NRPSFNRTPIG--------------------------------WLGS----------------------GDNTNYSIDI- AVP------VDGETEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Danio_rerio_MYOZ1_a -------------------------------------------------------------------------------- ---------------------------------------------------MPLSGTPAPPNKRKKPSKIITDLSHIAQD E------------------YESEPEASEFDLGKKI-----------------------------------RAPKDIMLEE LSLNKNKGSK------------------MFKMRQIRVEKFIYENNPDLF------------------------------- -------------------------------------SSESMDNLQKFVPSLG----GQMMD---------------VGG RLIGGQMAGHAGGVG-----QAPVPPPK--------PGSFGK-----------------------------------GAG GGLLAGGLAGGPGGVGGVGVSGGGVGGKDGLSVDISLTGDQSSKAALDKAKKSAEYVKTYISPWERAMKGNEDLLATMKA QMPSPCTFMELRKYKSFNR---------------------SAMPFGGFEKASQLMTFQLPDIEVATEEPEPAVVYQHDIN SRPSFNRTPIG--------------------------------WGGS----------------------AEPGSIHMELE TIP------FDGETDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Takifugu_rubripes_MYOZ1_b -------------------------------------------------------------------------------- ---------------------------------------------------MPMG-TPAPLHKRKKPPKIITDLTHITQD E------------------YESEPEASEFDLGKKI-----------------------------------KTPKEIMLEE LSLMKNRGSK------------------MFKMRQKRVEKFIYENNPDIF------------------------------- -------------------------------------TSESMDNLQKFVPSLGGQMGGQMIN---------------VGG HFLS-KEAGHLNFVGLHPGGGPPVPPPK--------PGSKRT-----------------------------------GAK GEGG-----AGGQGESDLEKTGKGEGGGGSSSLKDGLLMSIILTGSGSDGKNKYPHVKTYVSPWEKAMKGDKELIATLKA SMPGPHSQHDIPKWKSFNR---------------------CAMPFGGFDKANQFMKFQVPKPAP-KLDPEPAMVYQHDAA CRPSFNRTPIG--------------------------------WVGC----------------------SEPSSIHMDMN AVP------FDGETDEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Tetraodon_nigroviridis_MYOZ1_a -------------------------------------------------------------------------------- ---------------------------------------------------MPVG-TPAPLNKRKKAPKIITDLAHVTQD -------------------------ASEFDLGKKI-----------------------------------KTPKEIMLEE LSLMKNRGSK------------------MFKMRQQRVEKFIYENNPDLF------------------------------- -------------------------------------TSESMDNLQKFVPSLGGQMGGQMIN---------------VGG HSFS-KEAGHMNFVGLHRGGGHPVPPHK--------AWEQ---------------------------------------K GGG-------------NREKTGKGEGGGAAVPT-----MDVIVAGGRSDGKTKYPQAKTYVSPWEKAMKGDKELIATLKT SMPGPLSKKDIPKWKSFNR---------------------CAMPYGGFEKANQFMKFQLPKPAP-KLDPEPAMVYQHDAA CRPSFNRTPIG--------------------------------WVGS----------------------SEPSSIHMEA- -VP------FDGETDEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gasterosteus_aculeatus_MYOZ1_a -------------------------------------------------------------------------------- ---------------------------------------------------MPVG-RPATTAKRTKLSKIVTDLSHIAQD E------------------YESEPEASEFDLGTKI-----------------------------------RTPKDIMLEE LSLMKNKGSK------------------MFRMRQKRVERFIYENNPDIF------------------------------- -------------------------------------SSETMDNLQKFVPSLGAQMGGDMIN---------------VGG HFIS-KQVGLQHFGGPGAGRGPPVPPPK--------PGSKGA-----------------------------------GAG GAG----DAGGAGGLGGGD-LGKGE-QGEGAR------------GGSDDASGKLLLMKTYKSPWEKAMKGDETLIATMKG GMP-DFNKNDALKYKCFNR---------------------SAMPYGGFDKANQFMKFQVPKSEA-KEEPEPAVVYQPDIG CRPSFNRTPIG--------------------------------WVCS----------------------GEPGTINMETE AVA------YDGETDEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Oryzias_latipes_MYOZ1_a -------------------------------------------------------------------------------- ---------------------------------------------------MPLR-TPALLNKRKKPSKIITDLSHISQN E------------------YESEPEASEFDLGTKI-----------------------------------RTPKDIMLEE LSLMNNKGSK------------------MFRMRQKRVDRFIYENNPDIF------------------------------- -------------------------------------SSESMDSLQKFVPSLGGQMGGQTIN---------------VGG HHVS-KEHGHMYLGVIPVG-GAPVPPPK--------PGSKGV-----------------------------------GAG GAGSGF-GTDGAGGQGRGESLGNGQGAGEWSSQ---------KAGGKAGESKKQFVVKTYISPWEKAMKGDENLLATLKP MMPGPIDYKDLPKYKCFNR---------------------AAMPFGGFEKANQFMKFQMPEAQATKEEPEPSVVYQHDIG CRPSFNRTPIG--------------------------------WVGS----------------------NEPSSIHMETN AVP------FDGETDEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Homo_sapiens_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNTMMK-QRKQQATAIMKEVHGN--- ------------------------DVDGMDLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYQ-------------------------------- -------------------------------------SRAQINHSIAMQN-----GKVDGSNL--------------EGG SQQAPLTPPNTPDPRSPPNPDNIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWEQAISNDPELLEALYP KLFKPEGKAELPDYRSFNR---------------------VATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT DDT------TVPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gorilla_gorilla_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNTMVK-QRKQQATAIMKEVHGN--- ------------------------DVDGMDLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYQ-------------------------------- -------------------------------------SRAQINHSIAMQN-----EKVDGSNL--------------EGG SQQAPLTPPNTPDPRSPPNPDNIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWEQAISNDPELLEALYP KLFKPEGKAELPDYRSFNR---------------------VATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT DDT------TVPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Macaca_mulatta_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNAMVK-QRKQQATAIMKEVHGN--- ------------------------DVDSMDLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SRAQINHSIAMQN-----GKVDGSNL--------------ESG SQQAPLTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWEQAISNDPELLEALYP KLFKPEGKAELPDYRSFNR---------------------VATPFGGFEKASKIVKFKVPDFELLLLTDPRFMSFVNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT DDT------TIPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Mus_musculus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHSAMVK-QRKQQASAITKEIHGH--- ------------------------DVDGMDLGKKV-----------------------------------SIPRDIMIEE LSHFSNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SRAQINHNIAMQN-----GRVDGSNL--------------EGG SQQGPSTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTAVPKYYRSPWEQAIGSDPELLEALYP KLFKPEGKAELRDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFELLLLTDPRFLAFANPLS GRRCFNRAPKG--------------------------------WVSE----------------------NIPVVITTEPT EDA------TVPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Oryctolagus_cuniculus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHSTLVK-QRKQQASAIMKEIHGN--- ------------------------DVEGMDLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAQ------------------LFKMRQRRSDKYTFENFHYE-------------------------------- -------------------------------------TKAQINHNIAMQN-----GKLDGSNL--------------DGG SQQAPLTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTAVPKYYQSPWEQAIGDDPELLEALYP KLFKPEGKAELPDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFELLLLTDPRFMVFSNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT EEA------TVLESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Canis_familiaris_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNTMVK-QRKQQASAIMKEIHGN--- ------------------------DVDGMHLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SKAQINHSIAMQN-----GKLDGSNL--------------EGG SQQAPSTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWEQAISGDPELLEALYP KFFMPEGKAELPDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFELLLLTDPRFMAFTNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT EDT------TVPETEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Equus_caballus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNAMVK-QKKQQASAIMKEIHGN--- ------------------------DVDGMDLGKKV-----------------------------------SIPKDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SRAQINYNIAMQN-----EKLDGSNL--------------EGG SQPAPFTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWEQAISSDPELLEALYP KFFKPEGKVELPDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFDLLLLTDPRFMAFANPLS GRRSFNRTPKG--------------------------------WVSE----------------------NIPIVITTEPT EDT------TVPETEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Loxodonta_africana_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNTMVK-QRKQQASAIMKEIHGS--- ------------------------DLDGIDLGKKV-----------------------------------SIPRDIMLEE LSHLGNRGAR------------------LFKMRQRRSDKYTYENFQYE-------------------------------- -------------------------------------TKAQINHRIAMQN-----EKLDGSNL--------------EGG LQQAPTTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTAVPKYYQSPWEQAISSDPELLEALYP KFFKPEGRSELPDYRSFNR---------------------VATPFGGFEKASKMVKFKIPDFELLMLTDPRFMALTNPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTEPT EDT------TVPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Dasypus_novemcinctus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSYNTMVK-QRKEQASVIMKEIHGN--- ------------------------DVDGMDLGKKV-----------------------------------SIPRDIMLEE LSHLSNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SKAQMNHNIATQN-----EKLDGSNL--------------ESG SQQAPLTPPNTPDPRSPPNPDIIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTAIPKYYQSPWEQAISSDPELLEALYP KFFKPEEKVELPDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFELLLLTDPRFMVFANPLS GRRSFNRTPKG--------------------------------WISE----------------------NIPIVITTETT EDT------TVPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Myotis_lucifugus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHSSMVR-QRKQQAAAIMKEIHRH--- ------------------------GADGMDLGKKV-----------------------------------SVPRDIMLEE LSHLGNRGAR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------SRAQINHNLAMQN-----GKLDGSPS--------------EGG SQQAPFTPPNTPDPRSPPNPENIAPGYS-------GPLKEVP-------------------------------------- -----------------------------------------------PERFNTTAVPRSYQSPWEQAVSDHPELLEALYP RLLTPEGRAELPDYRSFNR---------------------VATPFGGFEKASKMVKFKVPDFELLLLTDSRFMAFANPLS GRRSFNRTPKG--------------------------------WISQ----------------------NIPIVITTEAP EEP------AVPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Monodelphis_domestica_MYOZ2 -------------------------------------------------------------------------------- ----------------------------------------------------------------------MKEIHGN--- ------------------------EVDGMDLGKKL-----------------------------------SIPRDIMLEE LSVLSNRGAR------------------LFKRRQRRSEKYTFENFHCE-------------------------------- -------------------------------------SKAEMNYRLAMQN-----GNLDGISM--------------EGG SQHGPLTPPNTPDPRSPPNPENIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTAVPKYYQSPWEQEISNEPELLEAFYP KLFKPEEKAELPDFRSFNR---------------------VAMPFGGFEKASKMVKFKVPDYDLLLLTDPRFMAFANPLS SRRSFNRTPKG--------------------------------WISE----------------------NVPIVITPVPT EEN------AVPETDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Ornithorhynchus_anatinus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHNALVK-QRKQQASAIMKEIHGN--- ------------------------DVDGHFLGKKV-----------------------------------STPRDIMPEE LSLLSNRGSR------------------LFKMRQRRSDKYTFENFQYE-------------------------------- -------------------------------------AKAQMDHSGALLN-----GKLESSNL--------------EAG SQHAPLTPPNSPDPRNPANPDSIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTSVPKYYQSPWEQAISDDPELLEALYP KLFKPEGKADLPDYRSFNR---------------------VATPFGGFEKASKLVKFKVPDFDLLLLTDPRFLAFANPLS SRRSFNRTPKG--------------------------------WTSE----------------------NIPIVITTGPV EEK------AAPETDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gallus_gallus_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHSAMVK-ERKQQASAIMDEIQRN--- ------------------------VSPSLNLGKKV-----------------------------------STPRDIMVEE LSTLSNRGAR------------------LFKRRQRRSDKYTYENYHYV-------------------------------- -------------------------------------ANKPRNRGEPIHS-----VKMDGLSV--------------EGI PQHAPMTPPNTPDPRSPPHPDNIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTSVPKYYQSPWIEAIRDDPELLEALYP KLFKPEAKPELPDYRSFNR---------------------VATPFGGFERASKLVKFKVPDYNLLMLNDPRFMILANPLA TRRSFNRTPKG--------------------------------WTSE----------------------NIPVVF-IQPS DSN------NVPETEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Taeniopygia_guttata_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSDSALAK-ERKEQASAIMDEIHRN--- ------------------------VSPTLNLGKKV-----------------------------------STPRDIMVEE LSTLSNRGAR------------------LFKRRQRRSDKYTYENYHYV-------------------------------- -------------------------------------ANKPRNRGEPIQS-----VRMDGLSV--------------EGI PQHAPMTPPNTPDPRSPPHPDNIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNTTAVPKYYQSPWIEAIRDDPELLEALYP KLFTPEAKPELPDYRSFNR---------------------VATPFGGFERASKLVKFKVPDYNMLMLNDPRFMILANPLA ARRSFNRTPKG--------------------------------WTSE----------------------NIPVVF-IQPA ESN------TVPETEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Anolis_carolinensis_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHADMVK-ERKQQASAIMKEIQRN--- ------------------------ESPGMDLGKKV-----------------------------------SIPRDIMLEE LSLLSNRGAR------------------LFKMRQRRSDKYTYENLHFL-------------------------------- -------------------------------------TSKPRNRSEIIQC-----VQLDTSGM--------------GAD QQHPPVTPPNTPDPRSPPNPETIAPGYS-------GPLKTIP-------------------------------------- -----------------------------------------------PEKFNTTSVPKYYRSPWIEAISNDPELLEALYP KLFKPEARPELPDFKSFNR---------------------VATPFGGFERASKLVKFKVPDFNFLLLNDPRFMVLANPLC TRRSFNRTPKG--------------------------------WTSE----------------------NIPIMITIQPS EVN------GVPETDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Pelodiscus_sinensis_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSHSAMVK-ERKQQASDIMKEIHRN--- ------------------------ESDGLDLGKKI-----------------------------------SIPRDIMVEE LSMLSNRGAR------------------LFKMRQRRSDKYTYENYHYL-------------------------------- -------------------------------------ANKQRNRSEPMQI-----LKMETRNA--------------EVS QQHAPMTPPNTPDPRSPPNPESIAPGYS-------GPLKEIP-------------------------------------- -----------------------------------------------PERFNTTSVPKYYQSPWIEAISNDPELLEALYP KLFKPEAKPELPDYRSFNR---------------------VATPFGGFERASKLVKFKVPDFNLLLLNDPRFMILANPLS TRRSFNRTPKG--------------------------------WTSE----------------------NIPIVF-IQPS DSN------TVPETDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Xenopus_tropicalis_MYOZ2 -------------------------------------------------------------------------------- ---------------------------------------------------MLSQSALNK-ERREQASAILKEIHGNGG- --------------------N---ESDGLDFGKKI-----------------------------------SVPRDIMLEE LSHVNNRGAR------------------LFKMRQRRSDKYTYENFPYA-------------------------------- -------------------------------------MKPQAAQQNQVNQNGNTEGNTEGNTL--------------DAN QQISPQTPPNTPDPRSPPNPENIAPGYT-------GPLKEIP-------------------------------------- -----------------------------------------------PEKFNETAVPKYYMSPWLEAIGSEPELLEALYP KLPVPGQKAEIPDYKSFNR---------------------AAIPFGGFDNASKLTTFKLPEFDLSPMIDPAVDMSPNPLK LRRSFNRMAQG--------------------------------WTSE----------------------NIPVFYSSDPI LNA------EIPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Danio_rerio_MYOZ2_b -------------------------------------------------------------------------------- ---------------------------------------------------MSQFSTLSVRERKMQAAALCHEVHGGVN- -------------------------GVTMDLGKKL-----------------------------------STPKDIMLEE LSLLSNRGSR------------------LFKMRQRRSDKYTFESIQNE-------------------------------- -------------------------------------ANALFNN---ENQANAENSENKGVAS--------------KTP PNTPDPRN--------PANPEDIAPGYG-------GPLTNIP-------------------------------------- -----------------------------------------------PERFNATAMPKSYHSPWEEAIINDPTLADTLKV HMPVPEPKVELPDYKSFNR---------------------VATPFGGFEKAPRGITFKLPEMDLN-TPQYPELQ-DHS-A KRPTFNRTAQG--------------------------------WISE----------------------GTPLILPTVSL EPF------EIPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Takifugu_rubripes_MYOZ2_a -------------------------------------------------------------------------------- --------------------------------------------------AMSQFSTMTTGERKMQAAAICREIHPQEG- ------------------------SDAEVDLGKKV-----------------------------------SVPKDIMLEE LSLTSNRGSR------------------LFKMRQKRSEKYTFESVHNE-------------------------------- -------------------------------------NNVQPNVALEFQVENGNTADGHDSQD--------------DSA NDQPSQVQTKMADSTKVANPESIAPGYG-------VPLKDVP-------------------------------------- -----------------------------------------------PEKFNSTAMPKSYQSPWEKAVGVNLALTEAPVP -CPPSQPQSDQPVYKSFNR---------------------VAIPFGGFSKEPRPDPVRTLKVEP--FPDYPELQ-GHTAP NQPSFNRSALG--------------------------------WVST----------------------CAPFPVPALPL EHV------HLPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Takifugu_rubripes_MYOZ2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------LNLGKKM-----------------------------------SVPKDIMMEE LNLSSNRGSR------------------MFQERQKRAERFTLENAING------------------VDNTSSVRNWET-- -----------------------------------MRTRSVLFKVVLMPSRCPHNKHHINSHIGLTGDCKLP-----LGV R-KHHLVKGLQKSVAAKGRPEVLAPGYS-------GPLKEAP-------------------------------------- -----------------------------------------------SEKFNTTVIPRSYCSPWTATLGGHEEVQNVLSA EL--LQNLPPPVSYRCFNR---------------------SAVPFG-GATASRRAIPVIS--FEAVESQQLPGVTLKRMC HRPNFNRAPRG--------------------------------WGVD----------------------YRLESNEL--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Tetraodon_nigroviridis_MYOZ2_a -------------------------------------------------------------------------------- ---------------------------------------------------------MTTKERKMQAALICREIQLHE-- -------------------------DAEMDLGIKV-----------------------------------SVPKDIMLEE LSSTTNRGSR------------------LFKMRQKRAEKYTFESNRNE-------------------------------- -------------------------------------NNTHPNATTEFQVNDGNSADDHDSTN--------------QSA DHQPSQVQPKTPDLTKVSSPESIAPXYG-------VPLKDVP-------------------------------------- -----------------------------------------------PQKFNSTAVPKSYQSPWEKVSGVDLVFIEPGVP -CAPSPPRSDQPAYKSFNR---------------------VAVPFGGFSHAHRPHPVKAPRLEP--LPDHPEIQ-GHTTP NQTSFNRSALG--------------------------------WTST----------------------CAPVPVSTLSL ERQ------PIPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Tetraodon_nigroviridis_MYOZ2_b -------------------------------------------------------------------------------- ---------------------------------------------------MSQFCTMPAGERKKRAAAICREVHGSN-- -------------------------GDLMDLGKKL-----------------------------------SIPKDIMLEE LSLLSNRGSR------------------LFKMRQRRSEKYTFESIQNE-------------------------------- -------------------------------------ANTQLSSLLCSSQNDVLNENTVTVEI--------------KVD P--PADDP--------PANTNSAAASGK-------NLLKAAA-------------------------------------- -----------------------------------------------AVQLDASSVPRSYHSPWEQEILSDPSLAETIKL RMPGPDPRPNLPEYKSFNR---------------------VATPFGGFKAITSQASRRLGPGTNP-SPSFPELQ-APG-M KRPSFNRTAQG--------------------------------WITE----------------------GTHMIVPTITL ESV------QVPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gasterosteus_aculeatus_MYOZ2_a -------------------------------------------------------------------------------- ---------------------------------------------------MSQFSTMTTRERQMQAAAICREVQAQED- --------------------------VEMDLGKKI-----------------------------------NVPKDIMLEE LSLASNRGSR------------------LFKMRQRRSEKYTFESIHNE-------------------------------- -------------------------------------NNKQLNSLIVIQPENLSATDNHSGQN--------------NMD VDQPPAVPSDTPDTSMEPNPDSIAPGYG-------GPLKDIP-------------------------------------- -----------------------------------------------PEKFNSTAVPKSYHSPWEQAIVSDPALADTLIP NMAEPEPRADLPGYKSFNR---------------------VATPFGGFGKAPRPAPTKSLLQEP--LPNYPELQ-GDTAV DRPSFNRSALG--------------------------------WVSN----------------------GGPIPLTVVSL DPI------LVPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gasterosteus_aculeatus_MYOZ2_b -------------------------------------------------------------------------------- --------------------------------------------------TMSQFCTMPTGERKKRAAAICQEVHGTNE- -------------------------GYVMDLGKKL-----------------------------------STPKDIMLEE LSLLSNRGSR------------------LFKMRQRRSEKYTFESIQNE-------------------------------- -------------------------------------ANTQLN----NGQNDILALNAHTVEI--------------KVD P--PTDGN--------TTNPEIIVSGNC-------ALRQYTT-------------------------------------- -----------------------------------------------AEKFTATAMPKSYHSPWDQAILSDPDLAETLKL TMSGPDPQPDPPEYKSFNR---------------------VATPFGGFDKAPRGITFKLPELDLN-PPRYHELQ-EPG-V KRPTFNRKAQG--------------------------------WISE----------------------GAPLILPTVTV EAV------NIPESDDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Oryzias_latipes_MYOZ2_a -------------------------------------------------------------------------------- --------------------------------------------------AMSRFTTMTTRERKMQAAAICREVHAQDE- --------------------H---NEFSMDLGKKM-----------------------------------SVPKDIMLEE LSLASNRGSR------------------LFKLRQRRSEKYTFENVHNQ-------------------------------- -------------------------------------NNMQLNNNAIPKSENETTTFTNGNED--------------NSR TNQPYKVTIDTLDTKMIPNPGIIAPGYG-------GPLKDIP-------------------------------------- -----------------------------------------------PEKFNSTAVPKSYRSPWEQAIINDPALADTLIT RMPHTKPQAECPGYKSFNR---------------------VATPFGGFIKAPRPVPDNQLQVET--FPDLQALQ-DDGGL HRPSFNRSALG--------------------------------WTST----------------------ASPAALPTVCP ELV------LIPESEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Ciona_intestinalis_MYOZ2 -----------------------------------------MSVSPKHSTTTPFSVTDILSPLEESYGTGSVEGIVSGRR EFSELYSNMESGAASSAGIHVPNLGGGGSTGSISSPMTSYRQPMMGTPPHHSIHHQQMSSANPYQTAAGMNGSYNLHPMP TPPQTSFHAMPGSGGPTG--YGNGGVPELPPYNNVQSPWYGAPSNPDPR------------------FVPSYPRLQITGY GSMMPGTGMDG-------------MHKTLLPPSQRRKRRVLFSQAQVFELERRFKQQKYLSAPEREHLAQMIHLTP---- ------------------------------TQVKIWFQNHRYKNKRSLKDKQTQEMSVQQQQQQ-------------QQQ SQTSGNAQPQHTNDLSHSNPSQLQPVASAVPGGTRTPQETYSP------------------------------------- --------------------------------------------VPTGVQASQPGMVDGNDGHRMVHISNQNGDQSSPRH LTMSDGSCHDSTIIESPNMQMPMPN---------VVQPTDTEAGLGPFSSVIKLEEVNVDSAEGSGGNSGNIVPQTHYLG STHHHDLMNVN---------------------------------VTT---------------------LNAVDAYQHHPH HNHIPIGNTVLNDQSILYSVYR---------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Drosophila_melanogaster_MYOZ2 -----------------------------------------------MSTESLNSLSDKELHRKLIQSGFPSTPVTETTR AVLIEKLRKHTRADKLKKRSNKYVLYSKEQQESPPFPQYHQYHAPQPPQNYANGLDNNNDLDQTGGSSAYNRSLDESDSS PLQLSASKMYAPPPVVASNYDGDCSPHSLGLNGKYLQPCSMPYAIDTSNNYGKPSGKAKLSDGGVVNRLLSFRDTTIQRK FNYPTGQASR-------------------IPLRKERLTRFALSDLKSFIRNPDIRPYVIPRVLISLFLIFLTIITVLYVG KRFEQSPIDKAALKYTLCNPNDMQMISEKVNCIEKDSLRGALDMSEELFRHLNERARLHHCKDANLSPALEIGEFVREMV SNPKTHRGNLHSNLMAAKYLITENPQWSIQVVDSTKHLGQTSHFELSEPNLPLKCIVLKKVTRFFTVIGALLLIVAGFLI VYVAVVIYRVKQKEALLAVDQFQKDIINELIYLSSQSESPEVVINQLQEKFLPAKKRSKLLSSWNKALKQLEKNDSRVLF GMVNRDGKAMRTIAWNRNVDKKDVG-------------LVKKWQSPAFDNSNKIANPPTPCLKIRHMFDSSEVDQANLKQ SIVESIIEKVG---------------TRCKICDVQLDVQSCCVYIRCASEEDAG-----TIHKEINGWWFDKRLISIKFL RLERYLSRFPKPSAEPLYFHTNEAANTHS--------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Homo_sapiens_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGPVMAAMGDLTEP--- -------------------------VPTLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQKFTFELAASQRA----MLAG--SARRKVTG---TAESG---- -------------------------------------TVANANGPEGP-NYRSELHIFPASPG---------------AS LGGPEGAHPAAAPAGCVPSPSALAPGYA-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAISKGYRCPWQEFVSYR-------DY QSDGRSHTPSPNDYRNFNK---------------------TPVPFGGPLVGGTFPRPGTP------FIP-EPLSGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gorilla_gorilla_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGPVMAAMGDLTEP--- -------------------------VPTLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQKFTFELAASQQA----MLAG--SARRKVTG---TAESG---- -------------------------------------TVANANGPEGP-NYRSEPHIFPASPG---------------AS LGGPEGAHPAAAPAGCVPSPSALAPGYA-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFVSYR-------DY QSDGRSHTPSPNDYRNFNK---------------------TPVPFGGPLVGGTFPRPGTP------FIP-EPLSGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Pongo_abelii_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGPVMAAMGDLTEP--- -------------------------VPMLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQKFTFELAASQRA----MLAG--SARRKVTG---TAESG---- -------------------------------------TVANANGPEGQ-NHRLELHIFPASPG---------------AS LGGPEGAHPAAAPAGCVPSPSALAPGYA-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFVSYR-------DY QSDGRSHTPSPNDYRNFNK---------------------TPVPFGGSLVGGTFPRLGTS------FIP-EPLSGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Mus_musculus_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKEPVMAVPGDLAEP--- -------------------------VPSLDLGKKL-----------------------------------SVPQDLMIEE LSLRNNRGSL------------------LFQKRQRRVQKFTFELSESLQA----ILAS--SARGKVAG---RAAQA---- ---------------------------------------TVPNGLEEQ-NHHSETHVFQGSP------------------ -GDPGITHLGAAGTGSVHSPSALAPGYS-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFTSYQ-------DY SSGSRSHTPIPRDYRNFNK---------------------TPVPFGGPHVREAIFHAGTP------FVP-ESFSGLELLR LRPNFNRVAQG--------------------------------WVR-----------------------KLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Oryctolagus_cuniculus_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGLAMSAPGDLSEP--- -------------------------VPLLDLGKKL-----------------------------------SVPQDLMIEE LSLRNNRGSL------------------LFQKRQRRVQRFTFELPDSQRL----SLAG--SAKRKALG---TAEPG---- -------------------------------------TV--ANGLEGQ-SYRSELHVFPGSP------------------ -GGLDDAHGTAALAESTRNPSALAPGYS-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFISYR-------DY LGDSSSHTLSPASYRNFNK---------------------TPVPFGGPLVGEAIPRAGTP------FVP-EPFNGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Canis_familiaris_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGSVMAAMGDLTGP--- -------------------------VPLLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQRFTFEFAASPQA----IADG--STKGKVLG---TAELG---- ---------------------------------------TVANGPEGQ-NFHSELHIFPASS------------------ -RGPEDAQSAAFPAERARSPSALAPGYA-------EPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFISYR-------DY QSEGRSHTPSLAEYRNFNK---------------------TPVPFGGPLVGETLPRAGTP------FVP-ELISGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Felis_catus_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGSVMAAMGDLTEP--- -------------------------VPLLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQRFTFEFPASQRA----LVDR--SAKGQVTGTVGTAEAGPL-- -----------------------------------HAQGKVANGLEGQ-SCSSELHIFRATP------------------ -GGPEVAQPSAFPAERPRSPSALAPGYA-------QPLKGVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFISYR-------DY QSDGRSHTPSPAEFRNFNK---------------------TPVPFGGPLVGETVPRAGTP------FVP-ELISGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Bos_taurus_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGPVMTTTGDLTEP--- -------------------------VPLLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQKFTFEFAASPRA----VVAG--SAKEKVTG---TAEPG---- -------------------------------------MVANSH--EGK-NYRSELHIYP-------------------AS HGGPGDAESMASRLVSTYNPSALAPGYA-------EPLKGIP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFISYR-------DY LGEGGSHTPSLVEYRNFNK---------------------TPMPFGGPLVGETLPRAGTP------FVP-ELTSGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Equus_caballus_MYOZ3 -------------------------------------------------------------------------------- ---------------------------------------------------------MIPKEQKGPVMAAMEDLAGP--- -------------------------VPVLDLGKKL-----------------------------------SVPQDLMMEE LSLRNNRGSL------------------LFQKRQRRVQKFTFEFAASQRA----VSKPPLCSQGNPLS---ARPCA---- ---------------------------------------QVTNGPEGQ-NYRSELHIFPASP------------------ -GGPEDAQPAASGAKSARSPSALAPGYA-------EPLKSVP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRCPWQEFISYR-------DY QSDGRSHTPSPAEYRNFNK---------------------TPVPFGGPLVGEAVPRAGTS------FIP-ELTSGLELLR LRPSFNRVAQG--------------------------------WVR-----------------------NLPE------- -------------SEDL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Monodelphis_domestica_MYOZ3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------PSLDLGKKV-----------------------------------SIPQDLMVEE LSLRSNRGSL------------------LFQKRQKRVQRFTFEAGCEWSLS---LEES--TASSGKPG---VLSCA---- ---------------------------------------QTASDPNGKENYRTEIQIFPTPP------------------ -LGPEISNQ-ELPQGRAPSPSALASGYS-------KPLTGIP-------------------------------------- -----------------------------------------------PEKFNHTAIPKGYRSPWQEFIGYKNGYK---DY HREQLNLTPRPSDYRSFNK---------------------TPVPFGGPLISETFPKMDIP------FIPKEPISGLELLS YRPSFNRVAQG--------------------------------WVR-----------------------SLLE------- -------------SEEL--------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Gallus_gallus_MYOZ3 -------------------------------------------------------------------------------- ----------------------------------------------------QPPSSHQG---PHPCSPLTSSA------ --------------------------PQLDLGKKV-----------------------------------STPQDVMLEE LSLSTNRGSQ------------------LFQQRQKRMQRFVFEHPSGY-------------------RKVPGPAGSHG-- -----------------------------------TERGEGAANEWTAGNAEGQQSFHSELHVAVSP----------HGG PPEVPKKTEKVLHMIKVLNPDSLAPGYS-------TPLKEVP-------------------------------------- -----------------------------------------------PEKFNITAIPKGYRSPWHGHMG-DEDKAVGSEN RLP---MKLPHGDFVNFNR---------------------TPTPFD--KAQLSDLFYVP-------PAELD-LSVLEVIS RRPNFNRVPQG--------------------------------WAR-----------------------VLPESDEL--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Taeniopygia_guttata_MYOZ3 -------------------------------------------------------------------------------- ------------------------------------------------------------------------PE------ --------------------------PQLDLGKKM-----------------------------------STTHDLMIEE LSLPHNRGSR------------------LFQQRQKRVQRFVLEHPSGS-------------------HHT-GKGDPEG-- -----------------------------------TVN-EQMVIPNGAGGAPPLPNYHSELHVAASP----------QGG PPEVPKKSEKVLHMSKVLNPSALAPGYS-------SPLKEIP-------------------------------------- -----------------------------------------------HEKFNVTAIPKGYRSPWQELFG-DRDNAN--AD PPP---MRPPAWDFRSFNR---------------------TPAPFD--RALVGELFSLP-------TVELDNLSVLEVIS HRPNFNRVAQG--------------------------------WVR-----------------------ILPESEEL--- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------- >Anolis_carolinensis_MYOZ3 -------------------------------------------------------------------------------- --------------------------------------------------MFPVPRLDLRREQHAPVSAIMKEIRE---- -----------------------KYGPKLDLGKKV--------------------------------