>Homo_sapiens_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPRE-PPAAPGAWRQQIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----AAVPGA----ANASA-----QQPRTPILLIR--------------------------------------------D NRT-AAARTRTAGSSGVTAG-RPRPTARHWFQAGYSTSRAREAGASRAENQTAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --EVPALSNLRPPSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGGRY RPGYGTGYFQY---------------------------------------GLPDLVADPYY-IQASTYVQKMSMYNLRCA AEENCLA---STAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDANT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Mus_musculus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWAVLLLGPLQLCPLLRCAP------QTPRE-PPAAPGAWRQTIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGAQYQPQRRRDPS---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----ATARRP----DGDAA-----SQPRTPILLLR--------------------------------------------D NRT-ASTRARTPSPSGVAAG-RPRPAARHWFQAGFSPSGARDGASRRAANRTASP------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --QPPQLSNLRPPSH---------IDRMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGSRN RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQKMSMYNLRCA AEENCLA---SSAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDANT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Pan_troglodytes_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPRE-PPAAPGAWRQQIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----AAVPGA----ANASA-----QQPRTPILLIR--------------------------------------------D NRT-AAARARTAGSSGVTAG-RPRPTARHWFQAGYSTTRAREAGASRAENQTAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --DVPALSNLQPPSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGGRY RPGYGTGYFQY---------------------------------------GLPDLVADPYY-IQASTYVQKMSMYNLRCA AEENCLA---STAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDANT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Callithrix_jacchus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTVLLLGPLQLCALVRCAPPAAGQRQPPRE-QPVAPGAWRQKIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----AAVPGA----AGASA-----QQPRTPILLIR--------------------------------------------D NRT-AAARARTAGSSGVTAG-RPRPAARHWFQPGYSSSGARDAGASRAENETAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --DVPALSTLQPLSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGGRY RPGYGTGYFQY---------------------------------------GLPDLVADPYY-IQASTYVQKMSMYNLRCA AEENCLA---STAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDANT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Macaca_mulatta_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTVFLLGPLQLCALVRCAPPAAGQQQPPRE-PPAAPGAWRQQIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----AAVPGA----ASASA-----QQPRTPILLIR--------------------------------------------D NRT-AAARARTAGSSGVTAG-RPRPTARHWFQAGYSTSGAREAGAPRAENQTAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --DVPELSNLQLPSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGGRY RPGYGTGYFQY---------------------------------------GLPDLVADPYY-IQASTYVQKMSMYNLRCA AEENCLA---STAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDANT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Rattus_norvegicus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTVLFLGQLQFCPLLRCAP------QAPRE-PPAAPGAWRQTIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGAQYQPQRRRDSS---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----ATAPRA----DGNAA-----AQPRTPILLLR--------------------------------------------D NRT-ASARARTPSPSGVAAG-RPRPAARHWFQVGFSPSGAGDGASRRAANRTASP------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --QPPQLSNLRPPSH---------VDRMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRSGSRH RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQKMSMYNLRCA AEENCLA---SSAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDAST- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYAADIDCQWIDITDVQPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNVVRCEIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Canis_familiaris_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTALLLGPLQLCALLRCAPPAAGQQQPPRQ-PPAAPAAWRQRIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----TTAPGA----ANAAA-----PQPRTPILLLR--------------------------------------------- NRT-AAARERAAGTAG-GAG-RPRPAARHWFQAGYSASGAR------DANQTAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --ERPALSNLRPPSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGSRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQKMSMYNLRCA AEENCLA---SSAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDAST- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNVVRCEIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Bos_taurus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRFAWTA-LLGSLQLCALVRCAPPAASHRQPPRE-QAAAPGAWRQKIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGSQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----ATAPGA----ANATA-----PQMRTPILLLR--------------------------------------------N NRT-AAARVRTAGPSAAAAG-RPRPAARHWFQAGYSTSGAHDAGTSRADNQTAPG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --EVPTLSNLRPPNRV-------DVDGMVGDDPYNPYKYT---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGSRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQKMAMYNLRCA AEENCLA---SSAYRGDVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDAST- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNVVRCEIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Equus_caballus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------------------MVG------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --RRPRTTPTSTP------------------------------------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGSRY RPGYGTGYFQY---------------------------------------GLPDLVADPYY-IQASTYVQKMPMYNLRCA AEENCLA---SSAYRSDVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDAGT- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YTNNVVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Dasypus_novemcinctus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------MRPTWTALLLGPLQLCALVRCAPPAVGQQQPPRE-PPAAPGAWRQRIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSLGAQYQPQRRRDPG---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----AAASAG----SSAAA-----GQPRTPILLLR--------------------------------------------D NRT-TAARTRAAGSSGVAVG-RPRPSARHWFQAGYSPSGARGADASLGDNQTAPA------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --ERPALSNLRPPSR---------VDGMVGDDPYNPYKYS---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRPGSRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQKMAMYNLRCA AEENCLA---STAYRADVRDYD--HRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDAST- QRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYHRRFA CTAHTQ-------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Ornithorhynchus_anatinus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------MVGDDPYNPYKYS---------------------------------------- -----EDNPYYNYYDTYER------------------------------------------------------PRQSGRY RPGYGTSYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQRMSMYNLRCA AEENCLA---SSAYRSDVRDYD--NRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDASS- HRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTAHTQK--GLSPGCYDTYGADIDCQWIDITDVQPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNVVRCDIRYTGHHAYASGCTI---------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Gallus_gallus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------MRCAP-PGLLLAQLHACIFWSGLWPAGCQ---------SPPAAWRQRIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVYSLLSQGAQYQPPRRRQAA---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----EPASSPVLLLRGNG------SVPRAAAAAAR--------------------------------------------P QPEPQPQAQPQPRPRSQPGG-SRGSGARHWFQAGYRAPSGSRAPAPRRRPRRRSRRR----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ERAERRRAAPSGLRP-------GREDVMVGDDPY-PYKYT---------------------------------------- -----DDNPYYNYYDTYER------------------------------------------------------PRQGSRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQRMSMYNLRCA AEENCLA---SSAYRADVRDYD--NRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDASS- HRKVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNIVRCDIRYTGHHAYASGCTISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Taeniopygia_guttata_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------MRFAP-PGLLLAQLHVCIYWSCLWPAACQQQPARRDPPPPPAAWRQRIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVYSLLSLGSQYQPPRRRQAA---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----EVAGSPILLLRNNGT-----ALPRRAAARA---------------------------------------------- -------AAPAAGSRG-------GSGARHWFQAGYQASSGGRAAAAPQSPAAATS------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --AAR---SASSCRP-------WQRVVMVRDDPT-PKITR---------------------------------------- -----NDMPYYYYDDGYER------------------------------------------------------RNLSNRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQRMSMYNLRCA AEENCLA---SSAYRADVRDYD--NRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLDASS- HRKVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNIVRCDIRYTGHHAYASGCTISP-------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Anolis_carolinensis_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------MRALP-LFPAWVCWLGLFWLQAEGLPPPRNP---APPPPPPAVWQQRIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------ENNGQVFSLLSVGSQYQPPRRRHSS---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----EAPQGNHVLLLRGNG-----TAPRRAASPA---------------------------------------------- ---------AAP---------SLAPAERHWFQAGGGGGGGGGGRGRGSEAASPPPPE----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- SAPSRSGNNSSSHTPPLNSLPRRRDDVMQGDDPYNPYKYT---------------------------------------- -----DDNPYYNYHDTYER------------------------------------------------------PRQGSRY RPGYGTGYFQY---------------------------------------GLPDLVPDPYY-IQASTYVQRTSMYNLRCA AEENCLA---SSAYRGDVRDYD--NRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ--HYHSMDEFSHYDLLEASS- HRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTAHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------LVPESD-- ----YSNNIVRCDIRYTGHHAYASGCSISPY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Danio_rerio_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MSMSLIDTFIYAFAHVCLLSCIAQTGQTQRQ-G-----NTGAAALRQTIQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------QHNGKLFSILSQGSEYQPPLKRDGN---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----KEQAQARPVAIVRN---------------DD--------------------------------------------A ATRTDSSAPSRASQSRGSVR-VPSGTG--ARGGASRWLSGDGARTRGVHGR---RNH----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- TDPLRSINGTDRPAGDDE--------VMVGDDPYNPYKSTD--------------------------------------- -----PDNPYYNYYDTYER------------------------------------------------------PRP--AQ RPGYGTGYFQN---------------------------------------GLPDLVGDPYY-IQASTYVQRVPMYNLRCA AEENCLA---SSAYRSSVRDYD--MRMLLRFPQRVKNQGTSDFLPSRPRYTWEWHSCHQ--HYHSMDEFSHYDLLDATT- HRRVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTSHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSY------------------------QVPESD-- ----YSNNVVRCDVRYTGNYAYVSGCHISQY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Takifugu_rubripes_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MGLRIRSTPLHAFACVYFLVFIVQAAQSQRNVGTHQRESPR-AALRQTLQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------SHNGKIFSILSQGSEYQPPRRRGAP---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----QEQVQARPLTIIKD----ASDPP---AAPQQ--------------------------------------------- QQGQQPPRPASGPR-NAAD--LPPPSQTLVRGREHRQHHRDRPAARPAAHRGSTANE----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- TQEKVTVS-PPLPRRED---------MMVGDDPYDPYKSTD--------------------------------------- -----GDNPYYNYYDVYER------------------------------------------------------PRP--RQ RPGYGTRIHQY---------------------------------------GLPDLVPDPYY-IQASAYVQSVPMYNLRCA AEENCLS---STAYSSSVRDYD--TRMLLRFPQRVRNQGTADFLPNRPRYAWEWHSCHQ--HFHSMDEFSHYNLLDANT- YHMVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRFA CTAHTQ---GLSPGCYDTYNAEIDCQWIDITDVKPGNYILKVSVNPYY------------------------QVPESD-- ----YSNNIVRCDVQYTGNYAYVSGCHLSSY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Tetraodon_nigroviridis_LOXa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MGLRIVGTPLYASGCVYFLVFLLQAVQPQRHVGTQERESPRAAALRQTLQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------SHNGKIFSILSQGSEYQPPRRRGAP---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----QEQVQARPLTIIKD----ASDQP---AAPQQ--------------------------------------------G QRGQRGQRGQRGQQPRRPE--PPPPPRGLVRGREHRQHHRER-------HR---ANE----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- TQEKVTVP-PPLPRRED---------MMVGDDPYDPYKSTD--------------------------------------- -----GDNPYYNYYDVYER------------------------------------------------------PRP--RA RPGYGTRIHQY---------------------------------------GLPDLVPDPYY-IQASAYVQSVPMYNLRCA AEENCLS---SSAYSSSVRDYD--SRMLLRFPQRVRNQGTADFLPNRPRYAWEWHSCHQ--HFHSMDEFSHYNLLDANT- YHMVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRFA CTAHTQ---GLSPGCYDTYNAEIDCQWIDITDVKPGNYILKVSVNPYY------------------------QVPESD-- ----YSNNIVRCDVQYTGNYAYVSGCHLSS-------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Gasterosteus_aculeatus_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MGLRVIGTPLYAYACVYSFVFLLRAVQSQTNPGTQQG-TKQIASLRQTLQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------SHNGNVFSILSQGAQYQPPRRRGAS---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----QQQVQARPVTIIRDGDARHPDTPGDAVAQRQ--------------------------------------------Q EQQQQQPPPRPGSEPQKPRG-LPSPLQRLVRGHEHRQHRDERLGARAGTQG--SSNG----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- TQEKVTVS-PPLPRRDD---------MMVGDDPYDPYKSTD--------------------------------------- -----GDNPYYNHYDVYER------------------------------------------------------PSR--RS RPGYGTSYHQY---------------------------------------GLPDLVPDAYY-IQASAYVQRVPMYSLRCA AEENCLS---SSAYSSSIRDYD--TRMLLRFPQRVKNQGTADFLPSRPRYTWEWHSCHQ--HFHSMDEFSHYELLDASS- QHSVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRFA CTSHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGDYILKISVNPNY------------------------HVPESD-- ----YSNNVVRCNVQYTGNYASVSGCHMSSY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Oryzias_latipes_LOXa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------MWLRQFGASRYAYARICLFVLSLHTVHSQRNPGSQQR-NEQSAALRQTLQW------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------SHNGKVFSILSQGAEYQPARRRGAP---------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----QEQVRAQQITIVQD-------------ADER--------------------------------------------R QDTQQQSVAR--QDQQPPRS-VPPQLQRLVRGPEHRQQLQHERFG----ER---VND----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- TQ-KVNVS-SSLPRRED---------MMVGDDPYDPYKSID--------------------------------------- -----GDNPYYNHYDVYER------------------------------------------------------PRE--RQ RPGYGTRYHQYV--------------------------------------GLPDLVPDPYY-IQASAYVQRSPMYNLRCA AEENCLS---SSAYRSSIRDYD--TRVLLRFPQRVKNQGTADFLPNRPRYSWEWHSCHQ--HFHSMDEFSHYDLLDATS- QRSVAEGHKASFCLEDTSCDY----------------------------------------------------GYYRRYA CTSHTQ---GLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPYY------------------------QVPEQD-- ----YSNNIVRCDVRYTGNYAYVSGCHMSTY------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Ciona_intestinalis_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------EGRVEIYHGG-EWGTICDDDWNIEAANVVCRMLGYDGAWEYLH-SGKFG-PGEGDILMDNVQCTGDESIISSCQ FNGWKN--HDCS-HHEDAGVKCNKIRLPGFHR------------------------------------------------ -------------------------------------------------------------------------------- --------------NLQT-------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------GDEGLDFIRLKPPRG--HRKRLPQLDGYVEFYHQKKWRKVCSTGWDLNTA-------- ----------------SVICGQ-LGFPRAKAIK----------------------------------------------- -------------------------------------------------------------------------LAYF--- -------------------LTRARARKKHYYWLSNITCIGTENKVSQCKFQNVD-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------ISAYNTCPG-EPLITRCIP GPKYARGNFKKGGKRRKHRKHSPQRQETIRLKVG---------------------------------------------S AEGEGRLEVMRSGRWGTVCH-RGWNLWAANVACRELGFG-TAKREIINSYFGAGHG-------PIWLTDLNCRGNETQLS DCQHG--------------------------------------------------------------------------- ----------YIST-----------------------------SECNHEHDAGVAC-------------------YVPQF NA------------------------------------------------------------------------NQRIRL VGGRNPMEG-RVEVKIRK------RWGAVCSNDWTMKEAMVVCRQLGLGFALHSLK-DVYFFPGTE-------------- ----NITEIAMTGIHCKGDELALQFCPSDGRS--------------------------------------LSVCGDPHRS STPFAGVICTE---------------------------------------LSPDLMQDIPL-LQQSLHLEDRPLHNLYCA SEEGCLSP-SAAKMD-----WPYGSRRLLRFSTRVWNRGRADFRPARSQDQWIWHQCHG--HYHSMAEFTHYDILDLN-- FTKVAEGHKASFCLEDSECSP----------------------------------------------------GVSPRFD CDQPGGGVQGIAVGCADNYQYNIDCQWIDISDITAGNYLIRIRVNPGT------------------------LVAESD-- ----FGNNEVICNLQYDGSRVWAWNCHIP------------------------------DDFDPEILIRY---------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----- >Ciona_savignyi_LOX -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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