>Homo_sapiens_GRIA1 -------------------------------------------------------------MCCSTHLFQPLQLA----- ---------GGLEWP--WSNLLC------------------------FLTPVKLHPEVWGLFPNQQSQEHAAFRFALSQL TEPP-------KLLPQIDIVNI--SDSFEMTYR----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFITPSFPVDTSNQ--------------FVLQLRPELQD-------ALISIIDHYKWQKFVYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNILTTTEEG----YRMLFQDLEKK-KERLVVVDCESERLN---AILG QIIKLEKNGI-GYHYILAN----LGFMDI-DLNKFKESGANVTGFQLVNYTDT----------IPAKIMQQWK------- -----NSDARDHTRVDWKRPK-----------YTSALTYDGVKVMAEAFQSLRR---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGRRTNYTLHVIEMKH-----DGIR K------------------IGYWNEDDK-------------FVPAATDAQAGG-------DNSSVQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVS-----DGKYGAR---DPD-TKAWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHSEEFEEG-------------------------RDQTT--SDQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------GPVNLAVLK-LSEQGVLDKLKSKWWYD---KGECGS KDS---------------------------------------GSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRNSGAGASSGG-SGENGRV----------- ---------------VSHDFPKS----MQSIPCMSHSSGMPLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Mus_musculus_GRIA1 -------------------------------------------------------------MPYIFAFFCTGFLG----- ---------AVVGAN--FPN----------------------------------NIQIGGLFPNQQSQEHAAFRFALSQL TEPP-------KLLPQIDIVNI--SDSFEMTYR----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFITPSFPVDTSNQ--------------FVLQLRPELQE-------ALISIIDHYKWQTFVYIYDAD RG--------LSVLQRVLDTAAEKNWQ--VTAVNILTTTEEG----YRMLFQDLEKK-KERLVVVDCESERLN---AILG QIVKLEKNGI-GYHYILAN----LGFMDI-DLNKFKESGANVTGFQLVNYTDT----------IPARIMQQWR------- -----TSDARDHTRVDWKRPK-----------YTSALTYDGVKVMAEAFQSLRR---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGRRTNYTLHVIEMKH-----DGIR K------------------IGYWNEDDK-------------FVPAATDAQAGG-------DNSSVQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVS-----DGKYGAR---DPD-TKAWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHSEEFEEG-------------------------RDQTT--SDQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRNSGAGASGGSGSGENGRV----------- ---------------VSQDFPKS----MQSIPCMSHSSGMPLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris_GRIA1 -------------------------------------------------------------MQHIFAFFCTGFLG----- ---------AVVGAN--FPN----------------------------------NIQIGGLFPNQQSQEHAAFRFALSQL TEPP-------KLLPQIDIVNI--SDSFEMTYR----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFITPSFPVDTSNQ--------------FVLQLRPELQD-------ALISIIDHYKWQKFVYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNILTTTEEG----YRMLFQDLEKK-KERLVVVDCESERLN---AILG QIIKLEKNGI-GYHYILAN----LGFMDI-DLNKFKESGANVTGFQLVNYTDT----------IPAKIMQQWK------- -----NSDARDHTRVDWKRPK-----------YTSALTYDGVKVMAEAFQSLRR---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGRRTNYTLHVIEMKH-----DGIR K------------------IGYWNEDDK-------------FVPAATDAQAGG-------DNSSVQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVS-----DGKYGAR---DPD-TKAWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHSEEFEEG-------------------------RDQTT--SDQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRNSGAGTSGG-GSGENGRV----------- ---------------VSHDFPKS----MQSIPCMSHSSGMPLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Bos_taurus_GRIA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------MTYR----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFITPSFPVDTSNQ--------------FVLQLRPELQD-------ALISIIDHYKWQKFVYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNILTTTEEG----YRMLFQDLEKK-KERLVVVDCESERLN---AILG QIVKLEKNGI-GYHYILAN----LGFMDI-DLNKFKESGANVTGFQLVNYTDT----------IPAKIMQQWK------- -----NSDARDHTRVDWKRPK-----------YTSALTYDGVKVMAEAFQNLRR---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGRRTNYTLHVIEMKH-----DGIR K------------------IGYWNEDDK-------------FVPAATDAQAGG-------DNSSVQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-DRYEGYCVELAAEIAKHVGYSYRLEIVS-----DGKYGAR---DPD-TKAWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHSEEFEEG-------------------------RDQTT--SDQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRNSGAGASGA-GSGENGRV----------- ---------------VSHDFPKS----MQSIPCMSHSSGMPLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus_GRIA1 -------------------------------------------------------------MQHIFAFFCTGFLG----- ---------AVLGAN--FPN----------------------------------NIQIGGLFPNQQAQEHAAFRFALSQF TDPP-------KLLPQIDIVNI--SDSFEMTYT----FCSQFSKG----------------------VYAIFGFY-ERKT VNMLTSFCGALHVCFITPSFPVDTSNQ--------------FVLQLRPELQD-------ALISIIDHYKWQKFVYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNILTTTEEG----YRMLFQDLEKK-KDRQVVVDCESERLN---AILG QIIKLEKNGI-GYHYILAN----LGFMDI-DLLKFK--GANVTGFQLVNYTDA----------VPAKIMQDWK------- -----TNDVKEQSRVDWHRLK-----------YTSALTYDGVKVMVDAFQSLRK---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGRRTNYTLHVIEMKA-----DGIR K------------------IGYWNEDDK-------------FVPAAIDTQTGF-------DNSSVQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-ERYEGYCVELAAEIAKHVGYSYRLEIVS-----DGKYGAR---DPE-SKAWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEEG-------------------------RDQTS--SDQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------GPVNLAVLK-LSEQGVLDKLKSKWWYD---KGECGS KDS---------------------------------------GSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TATLPRNSGAG-----GSGENGRV----------- ---------------VSHDFPKS----MQAIPCMSHSSGMPLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus_GRIA1 -------------------------------------------------------------MQHIFAFFCTSFLG----- ---------VVLGAN--FPN----------------------------------NIQIGGLFPNQQSQEHAAFRFALSQL TEPP-------KLLPQIDIVNI--SDSFEMTYT----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFITPSFPVETSNQ--------------FVLQLRPELQD-------ALISVIEHYSWQKFVYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNILTTTEEG----YRVLFQELQKK-KERLVVVDCESERLN---IILS KIIKLEKNGN-GYHYILAN----MGFMDI-DLTKFRESGANVTGFQLVNYTDT----------VPARIMQQWR------- -----NNDARELPRVDWKRPK-----------YTSALTYDGVRVMAEAFQNLRR---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LSG-NVQFN-EKGRRTNYTLHVIEMKH-----DGIR K------------------IGYWNEDEK-------------LVPVAIDTQTGN-------ESTSLQNRTYIVTTIL---E -DPYVMLKKNA------NQFEGN-ERYEGYCVELAAEIAKHVGYHYRLEIVR-----DGKYGAR---DPD-TKTWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEEG-------------------------RDQPA--NDQTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLEAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT---------EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSALR----------------------GPVNLAVLK-LSEQGVLDKLKSKWWYD---KGECGS KDS---------------------------------------GSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRPAAAG-----GSGENGRV----------- ---------------VSHDFPKS----MQTIPCMSHSTGMSLGATGL--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Anolis_carolinensis_GRIA1 -------------------------------------------------------------MQHIFAFFCTSFLG----- ---------AVLGVN--FPS----------------------------------NIQIGGLFPTQQSQEHAAFMFALSQF TEPP-------KLAPQIDIVNI--SDSFEMTYT----FCSQFSKG----------------------VYAIFGFY-ERRT VNMLTSFCGALHVCFVTPSFPVETSNQ--------------FVLQLRPELQD-------ALISVIEYYKCQKFTYIYDAD RG--------LSVLQKVLDTAAEKNWQ--VTAVNIMTATEKD----YKTLFLNLEKK-KERVVVVDCEAERLN---AILS KIVKIENNGK-GYHYILAT----LGFMDI-DLEKFRTNGANVTGFQLVNDTDT----------IPAKIMQQWK------- -----NNDAREQPRVDWKKPK-----------YTSALTYDGVRVMAEAFQSLRK---QRIDI------SRRGNAG----- -----------DCLANP--AVPWGQGI-DIQRALQQV--RFEG-LTG-NVQFN-EKGHRTNYTLHVMEMKA-----DGIK K------------------IGYWNEDEK-------------LVPTVTDQQGSN-------ETTTLQNRTYIVTTIL---E -SPYVMNKKSK------EKLEGN-LKYEGYCVELAAEIAKHVGYNYSLQIVK-----DGKYGAR---DPE-TKLWNGMVG ELVYG-RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHNEELEEG-------------------------RDQPA--NDHTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWTYMKSAEPSVFVPTT---------EEGMKRVRRSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALIEFC YKSRSESKRMKGFCLIPQQSINEAIR-------------------TSTLPRASAAGTS----SGENGRV----------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio_GRIA1_a -------------------------------------------------------------MQRSLTLLCTSFLG----- ---------LCFGSS--FPS----------------------------------NINIGGLFP-TESHEYEVFRFALSHH QDIP-------KLVPQVDMVKL--GNSFSMTYA----FCSQFSKG----------------------VYAIIGVY-DRKT VNMLMSFCGALHVCFVTPSFPMENSNQ--------------FVIQLRPELQD-------ALVGVIEHYRWSKFVYMYSSD SG--------LSVLQKVLDTAAEHNWL--VTSVNVETMTEAS----FLKVFQDLDKK-KEGQIIIDCELERLT---SILK KIIELGKNVK-SYHYILAN----LGFLDI-DLTEFKKGEANVTGFQLVNYADP----------NVSRTVQQWM------- -----EFDNKDAKVPKRRLK------------YTGALTYDGVKVMSTAFQNLRR---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--RIEG-LTG-HIQFN-EKGRRTNYSISVMELRP-----TGPK K------------------VGYWNEDEK-------------FVSTAAYMPGSN-------ETYGLQNRTYIVTTIL---E -SPYVMLKKNH------EHFTGN-DKYEGYCVELAAEIAKHVGYHYILKIVA-----DGKYGAR---DAE-TMMWNGMVG ELVYG-KADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHADDCEDGAEENPNQPSSSSAQPG----QNQQNQNQQS--QEQTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWSYMKSADPSVFVKTT---------DEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALVEFC YKSRTESRRMK-------QSINDAMH-------------------CSTLTRMSGNGNG-----GENGRI----------- ---------------VTHDFPKA----VQTLPCMSHAASMGLGASGM--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio_GRIA1_b -------------------------------------------------------------MWQSFVLLLTGLLG----- ---------LCSCSS--FPS----------------------------------NINIGGLFP-TDSHEYDVFRFALSQH NDVP-------KLVPQVDMVDT--GSSFAMTYA----FCSQFSKG----------------------VYAIIGLY-DRKT MNMLMSFCGALHVCFVTPSFPIDTNNQ--------------FVIQLRPELQD-------ALIALVEHYKWNKFVYMYSSD SG--------LTVLQKILDTAAEKTWQ--VTSINFDTLTEAA----FLKAIQDLDNK-KEFKIILDCELERLN---SILN LIAAQKKNLK-NYHYILAN----LGFLDL-NLTEFRKGGANVTGFQLMNYTNP----------TVSRTIQDWL------- -----EFDSKDLKSPKRRLK------------YTGALTYDGVTVMATAFQNLRK---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--QFEG-LTG-HVQFN-DKGHRTNFTVSVMEFGP-----SGPK K------------------VGYWNQREK-------------YVSTATYSNMLN-------ETFGLQNRTYVVTTIL---E -APYVMLKKNH------EQLVGN-DKYEGYCVELAAEIAKHVGYSYRLELVG-----DGKYGAR---DAE-TMMWNGMVG ELVYG-KADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHADDEEETADQQNQNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDGGS TKEFFRRSKIAVFEKMWSYMKSAEPTVFVKTT---------DEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------IPVNLAVLK-LNEQAVLDKLKNKWWYD---KGECGS KDS---------------------------------------ARKD-KTSALSLSNVAGVFYILIGGLGLAMLVALVEFC YKSRIESRRMK-------QIIDAAML-------------------SSTLTRM---GSG-----GENGRV----------- ---------------MAHDFPKG----AQTLPCMGQAAAMGLSTTGM--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes_GRIA1_a -------------------------------------------------------------MQRSFTIICTSLLG----- ---------ICLGSSLSFPS----------------------------------NINIGGLFP-TESHEYEVFRFALSHH QDIP-------KLVPQVDMVKM--GNSFSMTYA----FCSQFSKG----------------------VYAIIGLY-DRKT VNMLTSFCGALHVCFITPSFPIETANQ--------------FVIQLRPELQD-------ALVGVIEHYGWTKFVYMYSSD SG--------LSVLQKVLDTAAERDWL--VTSVNVETMTEAS----FLKVFQDLDKR-KEGQIIIDCETERLT---GILK KIVEQGKNAK-SYHYILAN----LGFLDI-DLTDLRKGGANITGFQLVNNSDP----------TVVSSSSGWS------- ------LTTKTPKCPRAALKY-----------YTGALTYDGVKVMSTAFQNLRR---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--RIDG-LTG-HIQFN-EKGRRTNYTVSIMELAP-----SGPK K------------------VGYWNEEEK-------------YVNTAVFVRGSN-------DTYGLQNRTYIVTTIL---E -SPYVMLKKNH------EQLVGN-DKYEGYIVELAAEIAKHVGYQYKLKLVS-----DGKYGAR---DPE-IKMWNGMVG ELVYG-KADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHAEDYEEGGEPQSPTQAAASNGVQQSQTPVQQNANQQS--QEQSNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWSYMKAADPSVFVRTT---------DEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALVEFC YKSRTESRRMK-------QSINDAMR-------------------CSTLTRMSGNGSS-----GENGRI----------- ---------------LTHDFPKT----VQTLPCMSHTASMGLGASCDHHVTMLDHKVQAGWGRRQKKSNKKTSETMAVRF YPSIPLAVDVHV-------------------------------------------------------------------- ------------------------ >Tetraodon_nigroviridis_GRIA1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------CSQFSKG----------------------VYAIIGLY-DRKT VNMLTSFCGALHVCFITPSFPIETANQ--------------FVIQLRPELQD-------ALVGVIEHYGWTKFVYMYSSD SG--------LSVLQKVLDTAAERNWL--VTSVNVETMTEAS----FLKVFQDLDKR-KEGQIIIDCETERLT---GILK KIVEQGKNAK-SYHYILAN----LGFLDI-DLTDLRKGGANITGFQLVNNSDP----------TVSRVVQQWV------- -----EFDNKDSKMAKSGLK------------YTGALTYDGVKVMSTAFQNLRR---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--RIDG-LTG-HIQFN-EKGRRTNYTVSIMELAP-----SGPK K------------------VGYWNEEEK-------------YVNTASFVRGSN-------DTYGLQNRTYIVTTIL---V -SLCKLIKKIA------EMFDIHPNRREGVTMDNCQWISENLVCDCKLDLLSRAVISQGKYGAR---DPE-TKMWNGMVG ELVYG-KADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHAEDYEN--------------------------ANQQS--PEQTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWSYMKAADPSVFVRTT---------DEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGEC-S GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALVEFC YKSRTESRRMK-------QSINDAMR-------------------CSTLTRMSGNGSS-----GENGRI----------- ---------------LTHDFPKT----VQTLPCMSHTASMGLGASGM--------------------------------- -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus_GRIA1_a -------------------------------------------------------------MQRSLTILYTSLLG----- ---------LCLGSSSSFPS----------------------------------NINIGGLFP-IESHEYEVFRFALSHH QDIP-------KLVPQVDMVKM--GNSFSMTYA----FCSQFSKG----------------------VYAIIGLY-DRKT VNMLMSFCGALHVCFVTPSFPIETANQ--------------FVIQLRPELQD-------ALVGVIDHYGWTKFVYMYSSD SG--------LSVLQKVLDTAAERNWL--VTSVNVETMTEAS----FLKVFQDLDKR-KEGQIIIDCETERLT---GILK KIVEQGKNAK-SYHYILAN----LGFLDI-DLTDLRKGGANITGFQLVNSSEP----------VVSRSISGWS------- ------LTTKTPKCPKVDSKY-----------YTGALTYDGVKVMYTAFQNLRK---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--RIDG-LTG-HIQFN-EKGRRTNYTVSVMELAP-----SGPK K------------------VGYWNEDEK-------------YVTTASFVRGSN-------ETYGLQNRTYIVTTIL---E -SPYVMLKKNH------EQLAGN-DKYEGYIVELAAEIAKHVGYQYKLKVVS-----DGKYGAR---DPE-TKMWNGMVG ELVYG-KADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHAEDYEEGGEPQTPTQASATNGMQ-GQTQTQQSTNQQS--PEQTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWSYMKAADPSVFVKTT---------DEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKECQTMCHDGPSVRGKAALLTSSIQTLLSLYLLILC PISQSGLYGMK-------QSINDAMR-------------------CSTLTRMSGNGSG-----GENGRI----------- ---------------LTHDFPKT----VQTLPCMSHTASMGLGASCDRHVTVLAAGNSQ--GGAEEEHRTMTSNIMAVWF DPSTRLAVICAR-------------------------------------------------------------------- ------------------------ >Oryzias_latipes_GRIA1_a -------------------------------------------------------------MQRSVTILYTSLLG----- ---------MCLGSSASFPS----------------------------------NINIGGLFP-TDSHEYEVFRFALSHH QDIP-------KLVPQVDMVKM--GNSFSMTYA----FCSQFSKG----------------------VYAIIGLY-DRKT VNMLMSFCGALHVCFVTPSFPIETANQ--------------FVIQLRPELQD-------ALVGVIDHYGWTKFVYMYSSD SG--------LSVLQKVLDTAAERNWQ--VTSVNVETMTEAS----FLKVFQDLDKR-KEGQIIIDCETERLT---GILK KIVEQGKNAK-SYHYILAN----LGFLDI-DLTDLRKGGANITGFQLVNNSEP----------TVSRIAQQWM------- -----EFDNKDNKMPKTGLK------------YTGALTYDGVKVMSMAFQNLRR---QRIDI------SRRGNAG----- -----------ECLANP--PAPWGQGI-DIQRALQQV--RIDG-LTG-HIQFN-EKGRRTNYTVSVMELAP-----SGPK K------------------VGYWNEDEK-------------YVTTTSFIRGSN-------DTYGLLNRTYIVTTIL---E -SPYVMLKKNH------EQLVGN-DRYEGYIVELAAEIAKHVGYQYKLKIVS-----DGKYGAR---DPENTKMWNGMVG ELVYG-KADLAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHAEDYEDGAEPQTPTQAAASNGVQQGQTPTQQNTNQQN--LEQTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDAGS TKEFFRRSKIAVFEKMWAYMKSADPSVFVKTT---------DEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NPVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKD-KTSALSLSNVAGVFYILIGGLGLAMLVALVEFC YKSRTESRRMK-------QSINDALR-------------------CSTLTRVSGNGSG-----GENGRI----------- ---------------LTHDFPKT----VQTLPCMSHTASMGLGAACDHHLTVLVGGR----------------------- -------------------------------------------------------------------------------- ------------------------ >Amphimedon_queenslandica_GRIA1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------MDPGLIES---------------NWDEVVEKFDDM N------------------------------------------------LKEELLRG------IYAYGFEKPS----AIQ QRAIIPCIKG---HDVIAQ-------------AQSGTGKTATFAISILQTIDE----------------KKQS------- ---------------------------------CQALILAPTRELAQQIQK----------------------------- --------------------VVIALGD--YQDILCHA--CIGG-----------TNVRSDIAKLE--------------- -----------------------------------------------------------------QGQHVVVGTPGR--- --VYDMINRNA----------------------LDTRFIRMFVLDEADEMLS--------------------RGFKDQIY DVFRKMPSNTQVVLLSAT-MPMEVLDVTKRFMRDPVRILVKKEELTL------EGIKQFYVQVEKEEWKLETLCDLYETL TITQAVIFVNTRRKVD--------------------------------------------------WLTEKMHSRD---- --------------------------------------------FTVSSMHGDME-------QKDR---DIIMKEFRSGS SRVLITTDLLARG------IDVQQVSLVINYD--------------------------LPANRENYIHRIGR------GG RFGRKGVAINFITR----DDER---------------------------------------------------------- ----------------------------------------------------MLKDIEVFYNTQVDEMPMNVADLI---- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Homo_sapiens_GRIA2 -------------------------------------------------------------MQKIMHISVLLSPV----- ---------LWGLIFGVSSN----------------------------------SIQIGGLFPRGADQEYSAFRVGMVQF STSE------FRLTPHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWDKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDKKDEMYRSLFQDLELK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLLKIQFGGANVSGFQIVDYDDS----------LVSKFIERWS------- -----TLEEKEYPGAHTTTIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGQGV-EIERALKQV--QVEG-LSG-NIKFD-QNGKRINYTINIMELKT-----NGPR K------------------IGYWSEVDK-------------MVVTLTELPSGN-------DTSGLENKTVVVTTIL---E -SPYVMMKKNH------EMLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVG-----DGKYGAR---DAD-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SSESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPSSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Mus_musculus_GRIA2 -------------------------------------------------------------MQKIMHISVLLSPV----- ---------LWGLIFGVSSN----------------------------------SIQIGGLFPRGADQEYSAFRVGMVQF STSE------FRLTPHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWDKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDKKDETYRSLFQDLELK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLLKIQFGGANVSGFQIVDYDDS----------LVSKFIERWS------- -----TLEEKEYPGAHTATIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGQGV-EIERALKQV--QVEG-LSG-NIKFD-QNGKRINYTINIMELKT-----NGPR K------------------IGYWSEVDK-------------MVVTLTELPSGN-------DTSGLENKTVVVTTIL---E -SPYVMMKKNH------EMLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVG-----DGKYGAR---DAD-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SSESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPSSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris_GRIA2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------M--IYPFYFSYS----VCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWDKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDKKDETYRSLFQDLELK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLLKIQFGGANVSGFQIVDYDDS----------LVSKFIERWS------- -----TLEEKEYPGAHTTTIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGQGV-EIERALKQV--QVEG-LSG-NIKFD-QNGKRINYTINIMELKT-----NGPR K------------------IGYWSEVDK-------------MVVTLTELPSGN-------DTSGLENKTVVVTTIL---E -SPYVMMKKNH------EMLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVG-----DGKYGAR---DAD-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SSESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------TPVNLAVLK-LSEQGVLDKLKNKWWYD---KGECGA KDS---------------------------------------GSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMKRPYALLNE------------------------------------MTLSDAMRSKARLS----------- ---------------ITGSTGENGRVMTPEFPKAVHAVPYVSPGMGMNVSVTDL-------------------------- -------------------------------------------------------------------------------- ------------------------ >Bos_taurus_GRIA2 -------------------------------------------------------------MQKIMHISVLLSPV----- ---------LWGLIFGVSSN----------------------------------SIQIGGLFPRGADQEYSAFRVGMVQF STSE------FRLTPHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWDKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDKKDETYRSLFQDLELK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLLKIQFGGANVSGFQIVDYDDS----------LVSKFIERWS------- -----TLEEKEYPGAHTTTIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGQGV-EIERALKQV--QVEG-LSG-NIKFD-QNGKRINYTINIMELKT-----NGPR K------------------IGYWSEVDK-------------MVVTLTELPSGN-------DTSGLENKTVVVTTIL---E -SPYVMMKKNH------EMLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVG-----DGKYGAR---DAD-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SSESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPSSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus_GRIA2 -------------------------------------------------------------MQKIMQISVFLFPV----- ---------FWGLIFGVSSN----------------------------------SIQIGGLFPRGADQEYSAFRVGMVQF STSE------FRLTPHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWDKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDRKDETYRSLFQDLEIK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLSKIQFGGANVSGFQIVDYEDS----------LVSKFVQRWS------- -----TLEEKEYPGAHTSTIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGQGV-EIERALKQV--QVEG-LTG-NIKFD-QNGKRINYTINIMELKT-----NGPR K------------------IGYWSEVDK-------------MVVTLTEIPSGN-------DTSGLENKTVVVTTIL---E -SPYVMMKKNH------EMLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVG-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SNESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMKSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------TPVNLAVLK-LSEQGVLDKLKNKWWYD---KGECGA KDS---------------------------------------GSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPTSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus_GRIA2 -------------------------------------------------------------MQKIMHISVCLAPV----- ---------LWGLIWGAHSN----------------------------------SIQIGGLFPRGADQEYSAFRVGMVQF STSE------FRLTPHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VFAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYQWTKFAYLYDSD RG--------LSTLQAVLDSAAEKKWQ--VTAINVGNINNDRKDETYRSLFQDLEVK-KERRVILDCERDKVN---DIVD QVITIGKHVK-GYHYIIAN----LGFTDG-DLSKIQFGGANVSGFQIVDYDDP----------LVSKFIQRWS------- -----TLEEKEYPGAHTSTIK-----------YTSALTYDAVQVMTEAFRNLRK---QRIEI------SRRGNAG----- -----------DCLANP--AVPWGHGV-EIERALKQV--QVEG-LTG-NIKFD-QNGKRINFTINVMELKS-----TGPR K------------------IGYWSEVDK-------------MVVNPLDGPLGN-------ESSGLENKTIIVTTIL---E -SPYVMMKKNH------EMLEGN-DRYEGYCVDLATEIAKHCGFKYKLTIVG-----DGKYGAR---DAD-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--TNESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIAVFDKMWTYMKSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPTSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Anolis_carolinensis_GRIA2 -----------------------------------------------------------MAMQKIRQIALSLAPL----- ---------VWGLIWGVYAN----------------------------------GVQIGGLFPRGADQEYSAFRVGLVQF STSD------FRLTSHIDNLEV--ANSFAVTNA----FCSQFSRG----------------------VFAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPTDGTHP--------------FVIQMRPDLKG-------ALLSLIEYYDWNKFAYLYDSD RG--------LSTLQAVLDTAAEKKWQ--VTAINVGNINNDRKDETYRSLFQDLELK-KERQVILDCERDKVN---DIVE QVITIGKHVK-GYHYIIAN----LGFNDG-DLSKIQFGGANVSGFQIVDYDDP----------LVSKFIQRWS------- -----TLEEKEYPGAHTSTIK-----------YTSALTYDAVKVMDAAFRNLRK---QRVEI------SRRGNAG----- -----------DCLANP--AVPWSHGV-EIERALKQV--QVEG-LTG-NIKFD-QNGKRINYTINVMELKS-----TGPR K------------------IGYWSELDK-------------LVVIPTDGLAGN-------DSSGLENKTIVVTTIM---E -SPYVMAKKNI------DLLEGN-ERYEGYCVDLAAEIAKHCGFKYKLTIVA-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEFEDGR-------------------------ETQ--SNESTNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLSKQT---EIAYGTLDSGS TKEFFRRSKIQVFDKMWTYMKSAEPSVFVRTT---------AEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------TPVNLAVLK-LSEQGVLDKLKNKWWYD---KGECGA KDS---------------------------------------GSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMK---------------------------------------------------VAKNAQN----------- ---------------INPTSSQN----SQNF--ATYKEGYNVYGIES-VKI----------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio_GRIA2_b -------------------------------------------------------------MQQLKNLSICLIAL----- ---------LLGMTTGGSP-----------------------------------SVQIGGLFPRGADQEYSAFRIGMVQF GTAE------FRLTPHIDNLEV--ANSFAVTNC----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPLDGNQQ--------------FIIQMRPDIKG-------PLLSLIEYYKWDKFAYLYDSD RG--------LTTLQVVLDTAAEKKWQ--VTAINVGNMKDERKDEAYRSLFQDLENK-KERRVILDCEQDKVK---DIME QVITIGRHVK-GYHYIIAN----LGFVDG-DLSKIQYGGANVSGFQIVDFDDP----------LVSKFDQRWE------- -----ALEEKEYPGADS-KIR-----------YTSALTYDAVQVMTEAFRYLHK---QRIDI------SRRANNG----- -----------DCLANP--AVPWAQGV-EIERALKQV--RVDG-LTG-NIQFD-QYGKRVNYTVNVMELKS-----NGAV K------------------IGYWNEVDK-------------MVVTKSDLFP-N-------DTMGLENKTVIVTTIL---E -APYVMLKKNA------DLFMDN-ERYEGYCVDLAAEIAKHCGFKYQLKIVG-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEYEDG--------------------------QIQ--TNESTNEFGIFNSLWFSLGAFMRQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIALFDKMWTYMKGAEPSVFVKTT---------AEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALVEFC YKSRAEAKRMKVTFS--------------------------------------------DAMRSKARLS----------- ---------------VTGSTGENGRVMSPEFPKAVHAVPFVRPGVGMNVSLTDLS------------------------- -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes_GRIA2_a -------------------------------------------------------------MEKIVNLSLSLLLV----- ---------LWGCALGGSP-----------------------------------SVQIGGLFPRGADQEYSAFRIGMVQF GTSE------FRLTPHIDNLEV--ANSFAVTNC----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPLDGNQQ--------------FIIQMRPDIKG-------PLLSLIEYYKWDKFAYLYDSD RG--------LTTLQVVLDTAAERKWQ--VTAINVGNLKDERKDEAYRSLFQDLENK-KERRVILDCEQDKVK---DIME QVITIGRHVK-GYHYIIAN----LGFIDG-DLSKIQYGGANVSGFQIVDFDDP----------LVSKFDQRWE------- -----ALEEKEYPGADS-KIR-----------YTSALTYDAVQVMTEAFRYLHK---QRIDF------TRRANNG----- -----------DCLANP--AVPWAQGV-EIERALKQV--RVEG-LTG-NIQFD-QHGKRVNYSVNIMELKT-----NGPV K------------------IGYWNEVDK-------------MAVTKSDVFA-N-------DTTGMENKTVIVTTIL---E -APYVMLKKNA------DLFVDN-ERYEGYCVDLAAEIAKHCGFKYQLKIVG-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEYEDG--------------------------QIQ--TNESTNEFGIFNSLWFSLGAFMRQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIALFDKMWSYMRSAEPSVFVKTT---------AEGVQRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSPLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMKMTFG--------------------------------------------DAMRNKARLS----------- ---------------ITGSTGENGRVMTPEFPKAVHAVPYVRPDMGLNVSLTDLS------------------------- -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus_GRIA2_a -------------------------------------------------------------MEPIVNLSVSVLLV----- ---------LWGCALGGSP-----------------------------------SVQIGGLFPRGADQEYSAFRIGMVQF GTSE------FRLTPHIDNLEV--ANSFAVTNC----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPLDGNQQ--------------FIIQMRPDIKG-------PLLSLIEYYKWDKFAYLYDSD RG--------LTTLQVVLDTAAERKWQ--VTAINVGNLKDEKKDEAYRSLFQDLETK-KERRVILDCEQDKVK---DIME QVITIGRHVK-GYHYIIAN----LGFIDG-DLTKIQYGGANVSGFQIVDFDDP----------LVSKFDQRWE------- -----ALEEKEYPGADS-KIR-----------YTSALTYDAVQVMTEAFRYLNK---QRIEF------TRKANNG----- -----------DCLANP--AVPWTQGV-EIERALKQV--RVDG-LTG-NIQFD-QHGKRVNYSVNIMELKT-----NGPV K------------------IGYWNEADK-------------MAVTKSDVFA-N-------DTTGMENKTVIVTTIL---E -APYVMLKKNA------DSYVDN-ERYEGYCVDLAAEIAKHCGFKYQLKIVG-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEYEDG--------------------------QIQ--TNESTNEFGIFNSLWFSLGAFMRQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIALFDKMWTYMRSAEPSVFVKTT---------AEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMKVAKN--------------------------------------------AQNVNPT-------------- ------------------SSQNSQNFATYKEGYNVYGIESVKI------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Oryzias_latipes_GRIA2_a --------------------------------------------------------------------LVSFLLV----- ---------LWGCALGGSP-----------------------------------GVQIGGLFPRGADQEYSAFRIGMVQF GTLE------FRLTPHIDNLEV--ANSFAVTNC----FCSQFSRG----------------------VYAIFGFY-DKKS VNTITSFCGTLHVSFITPSFPLDGNQQ--------------FIIQMRPDIKG-------PLLSLIEYYKWDKFAYLYDSD RG--------LTTLQVVLDTAAEKKWQ--VTAINVGNLKDERKDEAYRSLFQDLENK-KERRVILDCEQDKVK---DIMD QVITIGRHVK-GYHYIIAN----LGFVDG-DLSKIQYGGANVSGFQIVDFDDP----------LVSKFDQRWE------- -----ALEEKEYPGADS-KIR-----------YTSALTYDAVQVMTEAFRYLHK---QRIDF------TRRANTG----- -----------DCLANP--AVPWAQGV-EIERALKQV--RVEG-LTG-NIQFD-QHGKRVNYSVNIMELKN-----NGPV K------------------IGYWNEVDK-------------MVLTKLGEPS-N-------DTTGMENKTVIVTTIL---E -APYVMLKKNA------DLFVDN-ERYEGYCVDLAAEIAKHCGFKYQLKIVG-----DGKYGAR---DAE-TKIWNGMVG ELVYG-KADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHTEEYEDG--------------------------QIQ--TNESTNEFGIFNSLWFSLGAFMRQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIALFDKMWTYMRSAEPSVFVKTT---------AEGVQRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGIATPK----GSSLR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKEKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFC YKSRAEAKRMKMTFG--------------------------------------------DAMRNKARLS----------- ---------------VTGSTGENGRVMTPEFPKAVHAVPYVRPDMGLNVSLTDLS------------------------- -------------------------------------------------------------------------------- ------------------------ >Homo_sapiens_GRIA3 ------------------------------------------------------MARQKKMGQSVLRAVFFLVLG----- ---------LLGHSHGGFPN----------------------------------TISIGGLFMRNTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYHVDHLDS--SNSFSVTNA----FCSQFSRG----------------------VYAIFGFY-DQMS MNTLTSFCGALHTSFVTPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLGHYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGNIKDVQE---FRRIIEEMDRR-QEKRYLIDCEVERIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDI-LLERVMHGGANITGFQIVNNENP----------MVQQFIQRWV------- -----RLDEREFPEAKNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKV-----SGSR K------------------AGYWNEYER-------------FVPFSD-QQISN-------DSASSENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLAYEIAKHVRIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNNEEP-------------------------RDPQSPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPATN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Mus_musculus_GRIA3 ------------------------------------------------------------MGQSVLRAVFFLVLG----- ---------LLGHSHGGFPN----------------------------------TISIGGLFMRNTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYHVDHLDS--SNSFSVTNA----FCSQFSRG----------------------VYAIFGFY-DQMS MNTLTSFCGALHTSFVTPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLGYYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGNIKDIQE---FRRIIEEMDRR-QEKRYLIDCEVERIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDI-VLERVMHGGANITGFQIVNNENP----------MVQQFIQRWV------- -----RLDEREFPEAKNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKV-----SGSR K------------------AGYWNEYER-------------FVPFSD-QQISN-------DSSSSENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLAYEIAKHVRIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNNEEP-------------------------RDPQSPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPATN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Canis_familiaris_GRIA3 ------------------------------------------------------MARQKKMGQNVLRAVFLLVLG----- ---------LLGHSHGGFPN----------------------------------TISIGGLFMRNTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYHVDHLDS--SNSFSVTNA----FCSQFSRG----------------------VYAIFGFY-DQMS MNTLTSFCGALHTSFVTPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLGHYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGNIKDVQE---FRRIIEEMDRR-QEKRYLIDCEVERIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDI-LLERVMHGGANITGFQIVNNENP----------MVQQFIQRWV------- -----RLDEREFPEAKNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKV-----TGSR K------------------AGYWNEYER-------------FVPFSD-QQISN-------DSASSENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLAYEIAKHVRIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNNEEP-------------------------RDPQSPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------TPVNLAVLK-LSEQGILDKLKNKWWYD---KGECGA KDS---------------------------------------GSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPATN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Bos_taurus_GRIA3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------MRPALKG-------AILSLLGHYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGNIKDVQE---FRRIIEEMDRR-QEKRYLIDCEVERIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDI-LLERVMHGGANITGFQIVNNENP----------MVQQFIQRWV------- -----RLDEREFPEAKNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKV-----TGSR K------------------AGYWNEYER-------------FVPFSD-QQISN-------DSASAENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLAYEIAKHVRIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNNEEP-------------------------RDPQSPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPATN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Ornithorhynchus_anatinus_GRIA3 ---------------------------------------------------------LLQTQSHMHTSLHLYSQG----- ---------FVGLWFR-ISI----------------------------------SSFLGGLFMRNTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYHVDHLDS--SNSFSVTNA----FCSQFSRG----------------------VYAIFGFY-DQMS MNTLTSFCGALHTSFVTPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLTHYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGSIKDVQE---FRRIIEEMDRR-QEKRYLIDCEVERIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDL-VLERVMHGGANITGFQIVNNENP----------MVQQFLQRWV------- -----RLDEREFPEAKNSPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKV-----TGSR K------------------AGYWNEYER-------------FVPFLD-QQVSN-------DSTSVENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLAYEIAKHVGIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNNEEP-------------------------RDPQNPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------TPVNLAVLK-LSEQGILDKLKNKWWYD---KGECGA KDS---------------------------------------GSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPATN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Gallus_gallus_GRIA3 -------------------------------------------------------------------------------- ---------------------------------------------------------LGGLFMRNTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYHVDHLDS--SNSFSVTNA----FCSQFSRG----------------------VYAIFGFY-DQMS MNTLTSFCGALHTSFITPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLTYYKWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSVGSIKDVQE---FRRIIEEMDRR-QEKRYLIDCEVDRIN---TILE QVVILGKHSR-GYHYMLAN----LGFTDI-VLERVMHGGANVTGFQIVNNENP----------MVQQFLQRWV------- -----RLDEREFPEAKNSPLK-----------YTSALTHDAVLVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMKA-----SGSR K------------------AGYWNEYER-------------FVPTLD-QLPSN-------DTSSVENRTIVVTTIL---E -SPYVMYKKNH------EQLEGN-ERYEGYCVDLASEIAKHVGIKYKLSIVG-----DGKYGAR---DPE-TKIWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDGSEEP-------------------------RDPQNPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAESKRMKLT---------------------------------------------------KNTQN----------- ---------------FKPAPSTN----TQNY--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Anolis_carolinensis_GRIA3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------MS MNTLTSFCGALHTSFITPSFPTDADVQ--------------FVIQMRPALKG-------AILSLLTYYNWEKFVYLYDTE RG--------FSILQAIMEAAVQNNWQ--VTARSMGSIKDIQE---FKAIIEEMDKR-QEKRYLIDCEVERIN---TILE QVAILNKNSR-SYHYMLAN----LGFTDI-SLDKVVQGGANVTGFQIVNTENP----------MVQQFMQRWV------- -----RLDEREFPEAKNSPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TYGRRTNYTIDVYEMRP-----GGPR K------------------AGYWNEYER-------------FVPAVD-PSVSN-------DTSSVENRTIVVTTIL---E -APYVMRKQSP------DQKEGN-EKYEGYCVDLAYEIAKHVGIKYVLSIVP-----DGKYGAR---DPD-TKMWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLEDNQEEP-------------------------RDPQNPPDPPNEFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTT---------ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKNSCK-PCSIETQ----------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------ >Danio_rerio_GRIA3_a ----------------------------------------------------------------MTQSALIFLLW----- ---------LFGTSLAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNMTEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DKKS MNTLTSFCGALHTSFVTPSYPIDSDVQ--------------FVIQMRPPLKG-------AVLSLLSHYKWDKFVYLYDTD RG--------FSILQAIMEAAVANNWQ--VTARSVGSITDPQE---FRRIIEEMDRR-QEKRYLIDCEVDRIN---VILE QVVTLGKNSR-GYHYIIAN----LGFTNI-SLDKVFLGGANISGFQIINPENL----------VVQQFLQRWD------- -----RLDEREFPEAKNTPLK-----------YTSALSYDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-SFGRRTNYTIDVYEMKT-----GGPR K------------------IGYWNEFER-------------FVNIMD-QQFTN-------DSSSVENRTIVVTTIM---E -APYVMYKKNH------MHLEGN-EKYEGYCVDLASEIAKHVGIKYRLSIVM-----DGKYGAR---DPE-TKSWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWQLDET-DEV-------------------------KDPQTPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRAEAKRLKLE---------------------------------------------------KNAQN----------- ---------------YKPAPPAN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Danio_rerio_GRIA3_b -------------------------------------------------------------MRRRAHASVLLLPW----- ---------LVLQTQAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNITEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DRRS MNTLTSFCGALHTSFITPSFPTDTDVQ--------------FVLQMRPSLRG-------ALLSLLAHYKWEKFVYLYDTD RG--------FSILQAIMESAVMNNWQ--VTARSVGNIVDPLE---YRRIIEEMDRR-QEKRFLIDCEVERIN---SILE QVVIAGKNSR-GYHYILAN----LGFTNM-SLDKVFSGGANITGFQIINPDSP----------IVQQFLQRWE------- -----RLDEREFPESRSSPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDI------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-SFGRRSNYTVDVYEMKP-----GGAR K------------------IGYWNEFEK-------------FVYIVE-QQVTN-------ESSSVENRTIVVTTIM---E -APYVMYKRNY------MQLEGN-DRYEGYCVDLASEIAKHVGIKYKLSIVA-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLDDN-EET-------------------------KDPQTPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------TPVNLAVLK-LSEQGILDKLKNKWWYD---KGECGT KDS---------------------------------------GSKDKTS-ALSLSNVAGVFYILVGGLGLAMTVALVEFC YKSHQETKRLKLA---------------------------------------------------KNAQN----------- ---------------FKPAPPST----AQSF--TTYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Takifugu_rubripes_GRIA3_a ----------------------------------------------------------TEKSKKMAQRVVLLLLW----- ---------LLDLSSAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DKKS MNTLTSFCGALHTSFVTPSYPTDNEVQ--------------FVIQMRPALRG-------AVLSLLSHYKWQKFVYLYDTD RG--------FSILQAIMEAAVANNWQ--VTARSVSSTTDAAE---FRRIIEEMDRR-QEKRYVIDCEVDRIN---TIFE QVVTLGKNSR-GYHYILAN----LGFRNV-SLDKVFAGGANISGFQIVNPENP----------IVQQFMQRWE------- -----RLDEREFPEARNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKTV--QVQG-MTG-NIQFD-NYGRRTNYTIDIYEMKI-----GGPR K------------------IGHWNEYTG-------------FVNIMD-SQLSN-------DSS-VENRTIVVTTIM---E -APYVMYKKNY------MHLEGN-DRYEGYCVDLASEIAKHVGIKYKLSIVM-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWNLEDQ-DEA-------------------------KDPQTPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----SSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRQETKRLKLA---------------------------------------------------KNAQN----------- ---------------FKPTPPTN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Tetraodon_nigroviridis_GRIA3_a -------------------------------------------------------LTARGKMWHRTIATVLVLLR----- ---------FWGDSLAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNVTEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DRKS MNTLTSFCGALHTSFITPSFPIDADVQ--------------FVIQMRPGLRG-------AILSLLAHYKWEKFVYLYDTD RG--------FSILQAIMESAVANNWQ--VTARSVGNIVDPIE---FRRIIEEMDRR-QEKRFLIDCEVNRIN---SILE QVVTSGKNSR-GYHYILAN----LGFSNM-SLDRVFSGGANITGFQIISPDSP----------IVQQFLQRWE------- -----RLDEREFPEAKNTPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TFGRRANYTIDVYEMKS-----GGPR R------------------IGYWNEYEK-------------FVYVMD-QQVTN-------ESSSVENRTIVVTTIM---E -APYVMYKKNY------MQMDGN-DRYEGYCVDLASEIAKHVGIRYKLSIVP-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLDEN-DEF-------------------------KDPQSPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTT---------PDGVSRVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALG----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMTVASIEFC YKSRQETKRLKLA---------------------------------------------------KNAQN----------- ---------------FKPAPPAN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus_GRIA3_a ----------------------------------------------------------QIGSEKMAQRVVLLLLW----- ---------LCDGSFAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DKKS MNTLTSFCGALHTSFVTPSYPTDNEVQ--------------FVIQMRPALRG-------AVLSLLSHYKWQKFVYLYDTD RG--------FSILQAIMEAAVANNWQ--VTARSVSGTTDAAE---FKRIIEEMDRR-QEKRFVIDCEVDRIN---NILE QFVTLGKNSR-GYHYILAN----LGFTNV-SLDKVFAGGANISGFQIVNPENP----------IVQQFMQRWE------- -----RLDEREFPEARNTPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKTV--QVHG-MTG-NIQFD-NYGRRTNYTIDVYEMKT-----GGPR K------------------IGYWNEYAR-------------FVNIMD-PQVSN-------DSS-VENRTIVVTTIM---E -APYVMYKKNY------MHLDGN-DRYEGYCVDLASEIAKHVGIKYKLSIVM-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWNLEEQ-DET-------------------------KDPQTPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRQETKRLKLA---------------------------------------------------KNAQN----------- ---------------FKPAPPTN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Gasterosteus_aculeatus_GRIA3_b -------------------------------------------------------FTSRIKMWHRTPATVLVLLY----- ---------LWGDSLAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNATEKPFNLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAILGFY-DRKS MNTLTSFCGALHTSFITPSFPIDADVQ--------------FVIQMRPGLRG-------AVLSLLDHYKWEKFVYLYDTD RG--------FAILQAIMESAVANNWQ--VTARSVGNIVDPME---YRRIIEEMDRR-QEKRFLIDCEVGRIN---SILE QVVTSGKNGR-GYHYILAN----LGFSNM-SLDRVISGGANITGFQIINPDSP----------IVQQFLQRWE------- -----RLDEREFPEAKNTPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKMV--QVQG-MTG-NIQFD-TFGRRSNYTIDVYEMKT-----VGAR K------------------IGYWNEYEK-------------FVYIMD-QQVTN-------ESSSVENRTIVVTTIM---E -APYVMYKKNY------MQMDGN-DRYEGYCVDLASEIAKHVGIRYKLSVVP-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWHLDES-DEA-------------------------KDPQSPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--GAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALG----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMTVALIEFC YKSRQETKRLKLA---------------------------------------------------KNAQD----------- ---------------FKPAPPAN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Oryzias_latipes_GRIA3_a ----------------------------------------------------------IDRSEKMAQRVVLLLLW----- ---------LFDCTFAGFPN----------------------------------QINIGGLFMRSTVQEHSAFRFAVQLY NTNQNTTEKPFHLNYNVDNLES--SNSFSVTHA----FCSQFSRG----------------------VYAIFGFY-DKKS MNTLTSFCGALHTSFVTPSYPTDNEVQ--------------FVIQMRPALRG-------AVLSLLSHYKWQKFVYLYDTD RG--------FSILQAIMEAAVANNWQ--VTARSVSSTTDAAE---FRRIIEEMDRR-QEKRYVIDCEVDRIN---TILE QVVTLGKNSR-GYHYILAN----LGFSNV-SLDKVFAGGANISGFQIVNPENP----------IVQQFMQRWE------- -----RLDEREFPEARNAPLK-----------YTSALTHDAILVIAEAFRYLRR---QRVDV------SRRGSAG----- -----------DCLANP--AVPWSQGI-DIERALKTV--QVQG-MTG-NIQFD-NYGRRINYTIDVYEMKT-----GGPR K------------------IGYWNEYTR-------------FVNIMD-PQVSN-------DSS-VENRTIVVTTIM---E -APYVMYKKNF------IHLEGN-DRYEGYCVDLASEIAKHVGIKYKLSIVM-----DGKYGAR---DPE-TKTWNGMVG ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK------PGVFSFLDPLAYEIWMCIVFAYIGVSV VLFLVSRFSPYEWNLEEQ-DEI-------------------------KDPQTPPDPPNDFGIFNSLWFSLGAFMQQ-GCD ISPRS-LSGRIVGG---VWWFFT-------LIIISSYTANLAAFLTVERMVSPIE--SAEDLAKQT---EIAYGTLDSGS TKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTT---------PDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGG NLDSKGYGVATPK----GSALR----------------------NAVNLAVLK-LNEQGLLDKLKNKWWYD---KGECGS GGG---------------------------------------DSKDKTS-ALSLSNVAGVFYILVGGLGLAMMVALIEFC YKSRQETKRLKLA---------------------------------------------------KNAQN----------- ---------------FKPAPPTN----TQNF--ATYREGYNVYGTESVKI------------------------------ -------------------------------------------------------------------------------- ------------------------ >Ciona_intestinalis_GRIA3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------CNHMSQR----------------------THTIIGFW-KASS MNAIISYSDTFNIPWITPSLPLPDQPT-------------KHVINLHPKFET-------FLLDFLFKLGWKEFTLVYDQK E--------VHLPVKAAIAFCLERGLR--IQVRNLAGVDNILP------TLKEIACK-KEYKVLFDVSLQRSM---QTLE KIKIMGMLSM-DYHYIFSD----LSLIDQ-DLRQFAYGASNLTFLGLVDKSFE----------LYDSVLQGNV------- -----NKIMSIQLKKKICSILQ----------SESALIYDAFTAMASGMRQVIAE-GLVFET------EIQDEIN----- ------RVERVTCHQMS--ILPLNTGS-EISKAIKEV--KFQG-LTG-NVEFD-QQGQRINYSVRIYALDR-----LGLN S------------------IGTWTDSSEEGD--------GILELNDVDLVDQSD-----WILESYRNETLIVTTIV---E -EPYVIRKPNW------QELEGN-DRFEGFCVDLLKEITKIAQIQYRIKPVD-----DGQYGSK---NDK-DGTWNGMIG EVKYQ-KAHMAVAPLTITSAREAVVDFTKPFMTLGISIMIKKPEKQN------YNIFSFLDPLSTEIWICIVFAYVGVSV VLYLVSRFSPYEWHRRSLTK--------------------------VTN-NDEIDAATDFGIFNSLWFSLGAFVQQ-GCD ISPKS-FSGRIVGG---VWWLFT-------LIVISSYTANLAAFLTVDKMVTPIA--GAEDLAKQT---LIQYGTLRSGS TVNFFKQSPLPTYEKMWATMKSQEPSVFVSSN---------KEGIARVRASDGKYAFLMESTLNDYTEQRRPCNTMKVGP NIDSKGYGIALPK----GSPLY----------------------DTVNLAILT-LREQGKLQKLKNYWWYD---KSECGA NGG----------------------------------------SGATKTPALTLGNVAGVFYVLIGGMGLAICTALLEFW YHAHKIRNFKRK--------------------------------------------------QKAKGAV----------- ---------------TCGSLPVTS---IRPP--LSTVLAKQSWYE----------------------------------- -------------------------------------------------------------------------------- ------------------------ >Ciona_savignyi_GRIA3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------TILFS----VCNHISQR----------------------THAIVGFW-ESSS MSTIVSYSDTFSVPWITPSLPLPDTPT-------------KNVIFLHPKLEK-------FLLDLVYKLGWKQFTLVFDQQ EGILHFLILEHLPVKATLAFALKWKIK--VQVRNLAGEDNIFP------TLKEIACR-KEYKVLFDLKLTRSM---QILE KIKVMGMLSM-DYHYIFSD----LFLIEQ-DLMKFGHGASNLTFFGLVEKSSD----------LYESVLQGQS------- -----NNEFES-LGHIIY--LQ----------CDAALIYDAFSAMAMGMGQATSD-GLVFNS------ELDDDYG----- --