>Homo_sapiens_GPRIN3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALL CKNANGFSG---------APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAAS APSSAAGR-DLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNR-----EQPEKPSCPVGGVLSSSKDQ- VSCEFPSPETIQGTVQTPVTAARVVSHSSSP---------------VGGPEGERQGAICDSEMRSCKPLTRESGCSEN-- ----------------------------------------------KQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGP EKVPLPAQRQMSRFKEASTMTNQAES------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----EIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQ-EQL----------------------- --------------------RVICHS--SGSHTLELSDSTLAPQESSQCPGIMPQVHIQAA-AAESTAFQRENKLASLPG GVLK--------------TSSINLVSSNAQHTCKEDGRLAGMTP-VREESTAKKLAGTNSSSLKATAIDQISISACSQAE TSYGLGKFET-------------RPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSG-------------SLDPTNKGD AREKKPASPQVVKEKESTGTDT------SDAKTLLLNPKSQESGGTE----------------SAANPTPSPIRKNQEST LEENRQTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------TATSLSLPSDP-MGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQ K----------------------------------------------------------------------LNVTAAAAQ VGLTPGDKKKQ--LGA---------------------------------------------------------------- -----------------------------DSKLQLKQSKRVRDVVWD-----------------------EQGMTWEV-Y GASLDAESLG---------IAIQNHLQRQIREHEKLIKTQNSQT------------------------------------ ---------------RRSISSDTSSNKKLRGRQHSV-FQSMLQNFRRPNCCVRPAPSSVLD------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGTVPDPLRVTKASIVAASGKEESRGESQSVSPQ--PAQP DNNASGIGN---------VPAELSLQLSAAAQALMQACVSESSQQDMASPGVFSEGEPVSPKQKTPDDFLLHGSKESAAP GLNATAQK-ELISAPCLISVVQHTHHAIQRDAPNTSTCAVPEGSLVKSEANSNG-----ENPEKPGCPARVTCCSSKNQE GLCDFPSPENSQGILQTPDIASPSADR----------------------PEGEGQKVINNITAVSSEPPVR-EGCSEN-- ----------------------------------------------KQPSATALNTTAERSENPPPSHLTSKGATCSSEA RQALLPAQYPVSRFKEASTMTCQAES------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----GAKEVSGRAWQDAEVQAVASVESRSVSTSPSILPAYLKENPAPELENGQEQL----------------------- --------------------RVICHGKGSGNHLLELSNSMVDSQESRQCPSIVPQVHIQAA-TATPAAFKGGCKPANQPA EGLK--------------SPLIHVTSSQNTET-EEDLRLS-----ASKEATSRQPEGTNPDFQKANAIGQISLPAGSQAE INQGLWNSGP-------------REPEIVVKTAKDHKAESSCKPSNSGGGANKDYPPE-------------SLDPTDKKG AKDKKPASPLIVKDHAPGATST------LDAKTLLLNPKSQVKEGEG----------------PEVSPAPSPGRKSQQNT LEELRQPK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------TVMSLSLPSDG-TGDSSPGSGKRTPSLSVKASPRRGSRVSEFLKE- -----------------------------------------------------------------------LSVTAAAAQ VGLTPGEKKKQ--LGA---------------------------------------------------------------- -----------------------------DSKLHLKQSKRVRDVVWD-----------------------DQGMTWEV-Y GASLDPESLG---------VAIQNHLQRQIREHEKIVKTQSGQT------------------------------------ ---------------RRSISSDSSSSKKLKGRQHGV-LQSMLQNFRRPNCCVRPAPSSVLD------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Rattus_norvegicus_GPRIN3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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----------------------------------------MGTVPDPLRVTKASIVAASRKEESPGELQSVSPQ--PAQP DKNVSGIGN---------APAELSLRLSSAAPALMQACVHESSPQDMTSPGMLNEVEQVSPKNNTPDDSQPQGSKESAAP DANATAKK-ELTSAPFLMSAVQHMHHAIRNDPPNTSTCPVPEDSLVKSEANSDR-----EKPEKSSCPTRVTCCSSKNK- VFCDFPSPENSQGIVQTPDRASPSADR----------------------PEGEEQKAINSTTVVSSEPLAR-GECSEN-- ----------------------------------------------RQPSDTVLDTTDEKSENPPLSPLTSREATCSSEA RQVQLPTQHPTSRFKEASTMTCQAES------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----EAKEVPGRAWQDAEVQAVASVESRSVSTSPSILPAFLKENPALEQENGQEQL----------------------- --------------------RVICHDKGSGSRLLELSNSMVDPQESRQCPSIVPQVHIQAP-VATSTAFKGGCKPANQPA EGLK--------------SPLVHVASSQTPDT-EEDLRSS-----TSKEATSRELTGTNLGSQKATTIAQISVLAGSQAE ISLGLGNSGL-------------RAPELVEKIANDHKTEPDCKLSNSRGGVNEDQPLE-------------SLDPTDKRD AKDKNPASPLIVKDHAPGATST------PDAKTLLLNPKS--HGSEG----------------PEVSPAPSPGRKS---T VEEHRQTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------TVTSLSLPSDG-TGDSSPGSGKRTPSRSVKASPRRASRVSEFLKE- -----------------------------------------------------------------------LNVTAAAAQ VGLTPGEKKKQ--LGA---------------------------------------------------------------- -----------------------------ESKLQLKQSKRVRDVVWD-----------------------DQGMTWEV-Y GASLDPESLG---------VAIQNHLQRQIREHEKLVKTQSGQT------------------------------------ ---------------RRSISSDSSSSKKLKGRQQGV-LQSMLQNFRRPNCCVRPAPSSVLD------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGTVPDPLRSAKTSLIAASGKEEDLGEVRSAASQHRPALL CKNTNGLSG---------APAEAVLSPRAVAEALMQACEHETTQPDMSAPCVFSEVEKALPTLNSPGNPQQPGSSMPTAP ALSSTAGK-DLTQVSFTMPANQCTNQATLADQLQASLSSVPEHPQVKSQRTSGG-----EQLEKSGCPAEDSPGSSKDQ- VPYDFPSQETIQGTVQTPNAATPVCGHSASP---------------VSEPEGKRQQASCDSEPRSCESPAREFGCSEN-- ----------------------------------------------KQPFLIASDPLVVSSVTPQPFHLSSESSTFPPDP EKLLLPAKHQRSRFKEASTMTNQAES------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----EIKDTTNRTWQDAEVQAVASVKSRSVSTSPSILAAFLKENPTPKRFEQ-EQL----------------------- --------------------RVICHGSGSGSHTLELSDSILAPQEVSQSCGIVPEVHIQAA-AAGSTALQRESKLMSLPD KVLQ--------------ASPISVASNNAQDTSKVDGKSAGMTP-ERKDPISKQLSGTNSSSLKASPINQISICTGSQDE ISHGLQKSEA-------------KPSEFTVKTINDPQADADCKLPNSCVPASKAEQPE-------------SLDPAEKGG AGERKPSSPQTVKQPESAGTDTLGEKEKAEAKTLLLNPKPQENGDTG----------------SAANPTPSSLRKSQESA LEENKQTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------AATSLSLPSDS-MGDSSPGSGKRTPSRSVKASPRRASRVSEFLKEQ K----------------------------------------------------------------------LNVTAAAAQ VGLTPGEKKKQ--LGA---------------------------------------------------------------- -----------------------------DSKLQLKQSKRVRDVVWD-----------------------EQGMTWEV-Y GASLDPESLG---------IAIQNHLQRQIREHEKLIKAQSSQS------------------------------------ ---------------RRSISSDTSSNKKLKGRQHSV-FQSMLQNFRRPNCCVRPAPSSVLD------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Gallus_gallus_GPRIN3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGTVPHPLGPAKLSLVTAPEDKDHLGDLPPAKHQPKAHTA EKASNGFPC-TTLGSAASCTCDLKHTNTQRLE-------DDS-----LLSGLSSQAAEGPQAAVEPAP------------ ----VAVACSAGCGPDMMPAPQSSQQFMQGGQMRVNALVQVEDSAMKPQRAEEQ-------PVLQMTQCSSPSTPVGGNE S-CPTSQASLLQRGEEGGKAEEAGAQPASPA---------------RETTT---DPGRDPQEAVDAKSRAAVTEQLHP-- ----------------------------------------------ADQSETEQSSQLPAQLCHEGTHPVHDAGVEPGNL GPTHL------SKFRETGTMTVQSECSM---------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----LTQEAASRTWRDAEVQAVATVESKSASTSPSILAAFLKGNPPPEDK---EEL----------------------- --------------------HIIYQGSGGLSQSKLVDSFSSQQKSP-CSPGIVLKSTVG---MAVAATAQSQ--PAGLPG VSPHVVS----EASADNAKPTLPLSSAAATSQGTPVGAAEGTDAASGGKGNA-ALPVDAAALPKSVPVQQLTIHPHQQPA AGKENT----------------------APAAGTENNVQCLVHEAGSSQLP---LLCHTQ---------GETKQNEVLGS SE----QCQSATKVEVIP---QSAAKLKEE-NVMVLDAQGVVNTSS----EPI----------SRKAHTGEAGGEQQSRG QGEARQAA------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------EASKLQVEA--MAVPGCSSGHVSPHTEASTDPQQQGLQAKETRPEI H----------------------------------------------------------------------ATTCPSSAQ ALPNHGENKKQPTPAM---------------------------------------------------------------- -----------------------------EAKVQVKQSKHIRDVVWD-----------------------EQGMTWEV-Y GASLDPESLG---------IAIQNHLQRQIREHEKLIQAQNSQN------------------------------------ ---------------RKSISSDTSSNKKLKGRQHNV-FQSMLQNFRRPNCCVRPAPSSVLD------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MGTVPDPLRSAKLSLVTLSEEKNGLGELSP-KYQQKEATI ERNSNGYPFGAKVQPTEEQLFGVNCVAEANVQKTEQSCGYDTSSPTMLSPGSFNRSKEGCLETVNNSKQ-----EASSDC KGQVLVESHSLGQAALKAPAIQETNQVG-GELLFS----AVDDKASSPSKEGDC-------VMKNKTHETSSLLPSHPDT S----PTTPAVKQIVEEKFAPEKNGSPTSAK---------------ELEPVS--GLELKSPVCMDAKPKGVKDESSHP-- ----------------------------------------------SARTVPESLSKSKSE---NKSQPSLKG--ETIEE AVPEP------SKFRDTGTMTVPATR------------------------------------------------------ -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------ENISRTCQDAEVQAVASMESKSASTSPSIFAAFLKESMPSEAKQKQDQL----------------------- --------------------HIIYTAAGGKEQSEIVDNFTQKAPSTGIMPEVHIQAPAATKKKLVAQVVKTQDDPSGMMN AVCS-AS----LDKAEHPCPLASGCTQEISV----KEMEVQTPGVARYYSGLPQQMADSSVLQKTRPVYQISIHTSNQPL APSQPVNIET-------------TLPPCSGLPEVKSKHHHIGISVTENQPTSPSCGRQPE---------EDKVLPTTAGP HS-----TRTGEQLQIKTIS-DVDIKPKKEDSFVHPDSKEQKTSKR------------------AAVAVAVVGLQATCPP IAAQKERG------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------NFSATQKETGAIGLESEWSSNSAPDQETKTSERRKDPKLSR----- ------------------------------------------------------------------------TEAPASIQ PAASHGGKKKE--AKS---------------------------------------------------------------- -----------------------------EAKVHLKQSKHVRDVVWD-----------------------EQGMTWEV-Y GASLDPESLG---------IAIQNHLQRQIREHEKLLKAQNTQT------------------------------------ ---------------RKSISSDTSSNKKLKGRQHNV-FQSMMQNIRRPNCCVRPAASAVSD------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------MENVPNPKRTVTVQMLPQLASIDVLGNKELNANWDIE PKLTLNQDCSSGQKTKADQDNMHLKSSVKDSHTALLEGAVLEDKNMSCHDSEDHRR--PQNSHTNIKTSGQIVTDCDTNL NSHNINKEKNGNSTTKAPVVEEKRAS-------------------------KETMHNETPSLQKNSSPSDKIKSHLSE-- ------------------------------------------------SKDMSCTTSITTTASTSNTPSSAETLVSIQQP LKNQSTTAKEDTCSNDCKDFKP---------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------PGTASGLPVASTNTSHSVCTEAIDEEVQTQGAAP--------------------------- ---------------------------------------------------------------EVHCKLYREASTMTSAV DFGN-------------QRHDAEVQAVVTVCSQSTATSPSLLSQQVQQRAVGPLPEETDSISVVVEVKTTSEIHCSTPSV VSKPSQ--------------------------SGTVMVHVDADLQKESKLGAKPKEPLQ----------------NGQRG LSQLQPVYQINIETCSQSKQSNETT--------------------------------------CHLQSQAASTTAPQNAV KVSNKT-------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------DQDLQQKPTKTPTSKSEGVSAKLPMDITTATPPTSSSTPQSKKKLG -------------------------------------------------------------------------AKKLMPE KDDQDEEEN----------------------------------------------------------------------- ---------------------------------AKQSKKSVHDVVWD-----------------------EQGMTWEV-Y GASVDPESLG---------FAIQSHLQCKIKEHEKKIIAQTTFR------------------------------------ ------------------KSLSSPPGKNSKRRQVNVNFRSMFQNVRRPNCCARPSVQE---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Homo_sapiens_GPRIN1 -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGA GSSAMRDYC----------PSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSK ETLEAHGASISGTPEATTSGKP-----EPVSSVKTEPKSSDDRNPMFLEKMDFK-----SSKQADSTSIGKEDPGSSRKA DPMFTGKAEPEILGKGDPVAPGRMDPMTVRK---------------EDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRK-- ----------------------------------------------VDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVA PTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKL----------IPGSSGKNGPVSSGTGAPGSLGR LDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPV---------SGHTDTTASAKTDLTSLKNVDPMSSGK VDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAG-----TVSPGKEDPVSSRREDPISAGSRKTSS-EKVNPESSGKTNP VSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPL----------------------- --------------------AVGKEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKV GSLP------------LEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGS CRKAEP--LA-------------SGKGEPVSLGKADSAPS--RKTESPSLGKVVPLSL----------------EKTKPS SSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVS--STEASSLGQKDLEAAG----------AERSPCPEAAAPP-PGP RTRDNFTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------APSWEASAPPPPREDAGTQAGAQA-CVSVAVSPMSPQDGAGGSAFS FQAAPRAPS-------PPSRRDAGLQVSLGAAETRSVATGPMTPQA--------------------------AAPPAFPE VRVRPGSALAA--------------------------------------------------------------------- ------------------------------AVAPPEPAEPVRDVSWD-----------------------EKGMTWEV-Y GAAMEVEVLG---------MAIQKHLERQIEEHGRQGAPAPPP------------------------------------- -------AARAGPG--RSGSVRTAPPDGAAKRPPGL-FRALLQSVRRPRCCSRAGPTAE--------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----MRDCC----------SSP-KAIPAPPRHALDQSLGMDPRHTSSSGAAEGASCSERPAGSLACPSPNCSPLPETPR- ----AHGALTSDNSGTTLFGKP-----EPMSSAEATPTASEIRNPVFSGKMDGN-----SLKQADSTSTRKEEAGSLRNE ESMLKGKAEPMIYGKGEPGTVGRVDCTASGA---------------ENSGSLGKVDMPCSSKVDIVSPGGDNAG------ --------------------------------------------------SLRKVETISSGKMDPKT---ENVMHSRRER PGSTGEGDLVSLRENDMKPP--------DNTDSASTKKTDPEFSGKL----------TPGSSGKTELVSSVTVAPVTSEN VNPVCSGGAGPAAVGNSETLSSVKKDPQLLGKKEAVSSGEGGSVSVRMAETVSARQPEGMFPAKTDSTSSNSTGP--SGR ADPVSLRNSELVSPVKPERLSSGQAERVSLVKTE-----TLSSGKEDPRSSRRVDHTTVTGNMQTS-QKGNPESSGKTDL GSSSSGDTRSLGTWGSLSAAKAE-VTEGKGDPQPWKKASLPASEKTDPLASSKAGSA----------------------- --------------------SQGKAETVSPGEVDAMTLGKTVPTS-------SGKTALVSPGKVDLMTSERAEGIPELQA S----------------EKGNPVNSTRVDTGATGSTEPKSGVKVITQIPG---ATSPGKVETPSLQKEQPQLSEKTDP-- SRKVDP-----------------PTTVEPVSLGKADSASPSPRKAESQTSAKTVPQAP----------------DKATS- -SLRQSDGTPYSSAQPQRDTRSIGSLPEREPS---------ASTSQKDLAAAA----------AQKSPSAEAAAPP-PGP RTRDNFTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------APSWDAGAP-PPREDAGTQAGAQA-CVSVAVSPMSPQDGAGGPAFS FQAAPRAPSP---APRPPSRRDAGLQVSLGAAETRSVATGPMTPQAAA----------------------PPAVPPVFPE VRVRPGSVLAA--------------------------------------------------------------------- ------------------------------ALAPQEATEPVRDVSWD-----------------------EKGMTWEV-Y GASMEVEVLG---------MAIQKHLERQIEEHGRQGAPAPAPPP----------------------------------- -------AVRAGPG--RAGSVRTAPAEGAAKRPPGL-FRALLQSVRRPRCCSRAGPTAE--------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Loxodonta_africana_GPRIN1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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----MRECC----------PSQQKASSAPPRHSPDQGPGMDSRHSSPSGAVEGASCSEAPGGNLACPSPTCIPPQEAAIQ GTLGIHEALTSGTPETTFSVKPGVSKAEPVSSVKLDPTSSENRSPMFLEKMDSK-----SSKKADSTSTAKEDAGSSRKT DPIVTAQTEPTILGKGDPVSSGKMDPGSLGK---------------EDCMSSRKVNTVSPRKEDPGSLRKVDP------- -------------------------------------------------VSSGKVEPALPRKEDPGCSGKEHPVSSEKVG SASLGNVDPMSLENM----------------GSASAEKTDPGSLGKV----------TPGSSGKIELVSSGTVEPGSSGR GDPTGLGMADLIPVGNAEIVSSTKEDPKFLGKMDPASSGNGDPMSMRMMKTLSAGQMDPVFSGKMDPTSLKTVEPMSSDK VGSVFLGKVGPVSSGKPESLSSAQAKPVSVEKSD-----TPSSGKEVPVTSRKVDPISVGNIKASFYGKVNPESLGKKDP GSQ------VLGDCRAPSSVKPEAVTGIGVDHCPRRRRSLLSLGRLQ--------------------------------- ---------------------------------------ERRTQY-------SRKNIPVSWGKGDPIPSGKAGPSQRERV DLLP------------PEKGDSWNSRKVDPSASGKAELTSEGKAEPMPPGKEAAVSSGKAEAVCSQNEKPLASVNP--GS SGKADP--IA-------------SGKVAP--LGKAPSASP--RKPETPALGKVVPTTL----------------EKVEG- FSFRQSDGKSHGAAPSPEGVGSGRGSTEPEPALRI----EASSLGPKDPAVAR----------ATKSPGSEATATP-SGQ RTRDNFTK------------------------------------------------------------------------ -------------------------------------------------------------------------------- ----------------------------------APSWEASVLPPPREDAGTQAGAEA-CVSVAVSPMSPQDSAGDPAFS FQAAPRAPSP---APRPPLRRDAGLQVSLGAAETRSVATGPMTPQA--------------------------AAPPAFPE VRVRPGSALAA--------------------------------------------------------------------- ------------------------------AVAPPEAAEPVRDVSWD-----------------------EKGMTWEV-Y GAAMEVEVLG---------MAIQKHLERQIEEHGRQGAPAPPS------------------------------------- -------TSRPGLG--RSGSVRAAPPEGAAKRPPGL-FRALLQSVRRPRCCSRAGPTAE--------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------MMPNSPSPPPDNRAPNTAAG-----GAGAGRGPGVPLRGERPGARY RPR-RRR-RPTHAPPPPPRRSG------------------------------AERDAIAPEPPPPPQGLQATA------- -------------------------------------------------PWPRQPEQLLNPTRGSVTPGNGSFCGLAWEK PFPG-------MGSTR---------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------EPEALQLLSREAEDACEPGSSSSGCPPVGERLPSSGCTADGR----------------------- --------------------AM-----RTCCVSEPEALGTVEKVP---------------VP-TGPGSCGAPGGTAP--- -----------------------ACGPTEPGGTQKEKATP-------------VPPLPEPCLKAPNKDVGSVLALAKHVA F-------------------------LEPSAG------------------AELPSPMP----------------SQEQPG TGGTENPEQSQGVGEQGRA---------DRSTEST------------------------------QQPRTAKLLCGSYSF EVTP---------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------PQDAGVQ---DTGTQVDSRASLVSVALSPMSPPGGAAAFTFP KRELGS------APRPEPSKKDAEMQVSMP-VETRSVATGPMTPVAK-------------------------SPQASYPE VHVKG--------------------------------------------------------------------------- --------------------------------VAEEAPEPIREVSWD-----------------------EKGMTWEV-Y GASMEVEVLG---------MAIQKHLEKQIEEHGRQAVAT-PQS------------------------------------ ---------------TRASSVKGAPRKGEPKRQPSV-FRALLQNVRRPRCCSRAGPAVE--------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Anolis_carolinensis_GPRIN1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 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-------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----KCQKQAQ---EQ-------------------------------------------------QRPESG---C----- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ----------------------------------------MAAFK---EHTTAVETRHGEPLVKTCSIESPG-------- -------------LEQKPAKKDVEMQVSIP-VETRSVATGPMTPITK-------------------------SPQASYPE VHVKG--------------------------------------------------------------------------- --------------------------------AVEETPEPVKEVSWD-----------------------EKGMTWEV-Y GASMEVEVLG---------MAIQKHLEKQIEEHGRQVVMT-PQS------------------------------------ ---------------TRSSSIKGAPQKAEVKRQPSV-FRSLLQNVRRPRCCSRGGPAVE--------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------------------------------- >Homo_sapiens_GPRIN2 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