>Homo_sapiens_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELER-QGLTENGIPAVVWNIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVP----------------------------------------VELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFQD---GRNDVQ-ESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAKILENYNTLFEVEYTEN--------DHLR--CENLAR------------------------------------ --------------------LIIVKEVYYKNSLP-------------------------ILLTRGLERDMPKPPPKTKIP KSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK------ACLEDMNSAEGAISAKL-----------------VPSSQED ERPLSPFYLS----AHVPQVS--NVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASS--ATSARQRRRQS KEQD-----------------------------------EVRHG-RDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNT FGCAGERS-KPKRQKSSTKLSELHDNQDG--LVNMESLNSTRSHERTG-PDDFEWMSDE--RKGNEKDGGHTQ------- ---------------HFESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ EESFVSEVPQSDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EAHLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP -DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Mus_musculus_Fam13A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MACEIMP-----------------LRSSQED ERPLSPFYLS----AHVSQVS--NVSTTGELLERTIRSAVEEHLFDVSNAGDQSSEDSEPGPSSASS---IPTRQRGHQF KKQD-----------------------------------DVWHG-CDKELINKENIPSGFSGCAECILNSQEAERFQDDI CDYVGERS-KPKRQKSSSRLAKLSDNHDG--ALSMESLSSMQSQETLE-PEAAEPLSSE--SKEIERGGRDTQ------- ---------------HCENPTMKIQEHPSLSDTKQQRN-----------------------------------QDGE-DQ QESFVPDMPQLDLTALCDE----KTWE------------------------------------EPI---PSWQPENADSD EARLSPQAG-RLIHQFLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPVQLTRRIQTLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLTPRTRQRSNTLPKSFGSQLEKEDEKKQE---LLD----------------- KAIRPSVEATLEGILRKLQEKRVESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKTE RQIMKPLYDRYRLVKQILSRAS------TVPIIGS-----PSSKRRSPSLQPIIEGETASFFKEIKEQEEGSEDDSSTKP -DFAVTLKTDCSAHCFLDQLEDDADGFISPMDDKMP---------SKCSQDSGLSNLHSASIPELLEYLQEMR-----EE KKMIRKKLHDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKHIKAKLRLLEVLISKRDSDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Pan_troglodytes_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELER-QGLTENGIPAVVWNIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVP----------------------------------------VELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFQD---GRNDVQ-ESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAKILENYNTLFEVEYTEN--------DHLR--CENLAR------------------------------------ --------------------LIIVKEVCYKNSLP-------------------------ILLTRGLERDMPKPPPKTKIP KSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK------ACLEDMNSAEGAISAKL-----------------VPSSQED ERPLSPFYLS----AHVPQVS--NVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASS--ATSARQRRRQS KEQD-----------------------------------EVRHG-RDKGLINKENTPSGFSHLDDCILNTQEVEKVHKNT FGCAGERS-KPKRQKSSTKLSELHDNQDG--LVNMESLNSTRSHERTG-PDDFEWMSDE--RKGNEKDGGHTQ------- ---------------HFESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ EESFVSEVPQLDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EAHLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP -DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Gorilla_gorilla_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELER-QGLTENGIPAVVWNIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVP----------------------------------------VELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFQD---GRNDVQ-ESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAKILENYNTLFEVEYTEN--------DHLR--CEDLAR------------------------------------ --------------------LIIVKEVCYKNSLP-------------------------ILLTRGLERDMPKPPPKTKIP KSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK------ACLEDMNSAEGAISAKL-----------------VPSSQED ERPLSPFYLS----AHVPQVS--NVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTLSASS--ATSARQRRRQS KEQD-----------------------------------EVRHG-RDKGLINKENTPSGFNHLDDCILNTQEVEKVHKNT FGCAGERS-KPKRQKSSTKLSELHDNQDG--LVNMESLNSTRSHERTG-PDDFEWMSDE--RKGNEKDGGHTQ------- ---------------HFESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ EESFVSEVPQLDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EAHLSPQAG-CLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP -DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Callithrix_jacchus_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELER-QGLTENGIPGVVWNIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVP----------------------------------------VELGRDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFHD---GRNDVQ-KSSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAKILENYNTLFEVEYTEN--------DHLR--CENLAR------------------------------------ --------------------LIIVKEASCKNSLP-------------------------ILLTRGLERDMPKPPPKTKIP KSRSEGSFQVHRVLQPELSDGIPQLSLWLSRRK------SCLEDMNSTEDAHSAKL-----------------ASSSQED ERPMSPFYLS----AHVPQVS--NVSTTGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTPPASS--ATSARQRRRQS KEQD-----------------------------------EVRRG-RDKGLINKENIPSGFNNLGDCILNTQEVEKVHENT SGCVGERS-KPKRQKSDTKLSELHDNQYG--PVNMESLNSTGSHERTG-PDDFEWMSDE--SKGNEKDGGHSQ------- ---------------HLESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ QESFVSEVPQLDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNAHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LAD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNTKP -DFMVTLKTDFSARCLLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMK-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Pongo_abelii_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELQR-QGLTENGIPAVVWSIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVP----------------------------------------VELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFQD---GRNDVQ-ESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAKILENYNTLFEVEYTEN--------DHLR--CENLAR------------------------------------ --------------------LIIVKEASYKNSPS-------------------------ILLTRGLERDMPKPPPKTKIP KSRSEGSIQAHRVLQPELSDGIPQLSLRLSRRK------SCLEDS--AEDAISAKL-----------------VPSSQED ERPLSPFYLS----AHVPQVS--NVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTPSASS--ATSARQRRRQS KEQD-----------------------------------EVRRG-KDKGLTNKENIPSGFNHLDDCILNTQEVEKVHENT SGCAGERS-KPKRQKSSTKLSELHDNQDG--LVNMESLNSTRSHERTG-PDDFEWMSDE--RKGNEKDGGHTQ------- ---------------HFESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ EESFVSEVPQLDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EAHLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAEGSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP -DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Macaca_mulatta_FAM13A -----------------------------------QSKAAVRLKEDMKKIVAVPLNEQKD-------------------- --------------FTYQKLFGVSLQELQR-QGLTKNGIPAIVWNIVEYLTQH-GLTQEGLFRVNGNVKVVEQLRLKFES GVS----------------------------------------VELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFI QLFQD---GRKDVQ-ESSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD LCNKIMAAILENYNTLFEVEYTEN--------DQPR--CENLAR------------------------------------ --------------------LIIVKEASYKNSLP-------------------------ILLTRGLEKDMPKPPPKTKIP KSRSEGSIQTHRVLQPELSDGIPQLSLWLSHRK------SCLEDMNSAEDASSAKL-----------------VPSSQED ERPISPFYLS----AHVPQVS--NVSATGELLERTIRSAVEQHLFDVNNSGGQSSEDSESGTPSASS--ATSARQRRRQS KEQD-----------------------------------EVRHG-RDKGLINKENIPSGFNHLDDCILNTQEVEKVHENT SGCVGERS-KPKRQKSSTKLSELHDNQDG--LVNMESLNSTRSHERTG-PDGFERMSDE--RKGGEKDGGHTQ------- ---------------HFESPTMKIQEHPSLSDTKQQRN-----------------------------------QDAG-DQ QESFVSEVPQLDLTALCDE----KNWE------------------------------------EPIPAFSSWQRENSDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANAEVLKW TN----DLAKFRRQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKP -DFMVTLKPDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Rattus_norvegicus_Fam13A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------MACEIMP-----------------LRSSQED ERPLSPFYLS----AHVSQVS--SVSTTGELLERTIRSAVEEHLFDVNSSADQSSEDSEPGPSSASS---TPTRQRGHQF KKQD-----------------------------------DVWYG-QDKELINKENIPCGLSSCDECILNSQEAERFQDDI CEYVGERS-KAKRQKSSSRLAELCENHDG--HLSTESLSSMQTQETAE-PEAVELRSSE--SKEAERSWRDTQ------- ---------------HCESPAMKIQEHPSISDTKQQRN-----------------------------------QDDD-DQ QESFVPDLPQLDLTALCD-----KTWE------------------------------------EPI---PSWQQENVESD EARLSPQAG-RLIHQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPVQLTRRIQTLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKETKLKISEE--DLTPRTRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIRPSVEATLEGILRKLQEKRMESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKTE RQIMKPLYDRYRLVKQILSRAS------TVPIIGS-----PSSKRRSPSLQPIIEGETASFFKEIKEQEEGSEDDSSTKP -DFTVTLKTDSSAHCFLDQLEDDADGFISPMDDKMP---------SKCSQDSGLSNLHSASIPELLEYLQEIR-----EE KKMIRKKLHDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKHIKAKLRLLEVLISKRDADSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Canis_familiaris_FAM13A ----------MFSSGLHHFYEALPARMGAGALAICQSKAAVRLKEDMKKIVAVPLNEQRN-------------------- --------------SSYKKLFGVSLQDLQQ-QGLTENGIPAIVGTLVDYLTKH-GLTQEGLFRVNGNVKVVEQLRWKFES GAP----------------------------------------VELGKDGDVCSAASLLKLFLRELPESVITSTLYPRFI QLFQD---DRNDAQ-ENSLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVENRMNVHNLATVFGPNCFHVPPGLEGMKEQD ICNKIMAKLLENYNTLFEVEHTEN--------DNQR--YENLAR------------------------------------ --------------------LIIVKEASCKNPLPN------------------------ILLTKDLERDMQKPSLKTRIP KSRSEGSIQAHRVPQSELCDGLPQVSLQLSRRK------PYWDDMSSAEDANVAKL-----------------VSSSQED ERPISPFYLS----AHVSQVS--SVSTTGELLERTIRSAVEQHLFDVNGSGGQSSEDSESGPSSASS--ATSARQRRRQS KEQD-----------------------------------EVRRG-RDVGLINKENIPSGFNSLEDCILNPQEVEKLYENT SSYIGERG-KPKRQKSSSKLSELNENQDG--LLNMESLSSTASHERPG-TDDVELMSDE--SKENEKDGRHTP------- ---------------HFESPTMKIQEHPSIPDTKLQRT-----------------------------------QDTD-DQ QESFVSEVPELDLTALCDE----KSWE------------------------------------DPVPTFS-WQQESVDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LID----------------- KAVKPSVEATLESIQRKLQEKRTESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEDEGSEDDSNTKP -DFTVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNIQKEDRAPMAEEYNEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Felis_catus_FAM13A --------------------------MGAGALAICQSKAAVRLKEDMKKIVAVPLNEQRS-------------------- --------------STYKKLFGVSLQDLQQ-QGLTENGIPAIVGDIVEYLTKH-GLTQEGLFRVNGNVKVVEQLRWKFES GVP----------------------------------------VELGKDGDVCSAASLLKLFLRELPERVITSALQPRFI QLFQD---DRNDAQ-DSSLRALIKELPDVHYCLLKYLCQFLTEVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQD ICNKIMAKLLENYDTLFEVEYTGN--------DNQR--CENMAR------------------------------------ --------------------IIIVKEASCKNPLP-------------------------ILLTKDLD--MQKPSLKTRIP KSRSEGSIQSHRVPQPELSDGVPQVSLRLSRRK------PYWNDVNSAENFRIYFP-----------------FSS-QED ERPMSPFYLS----THVSQVS--NVSTTGELLERTIRSAVEQHLFDVNGPGGQSSEDSESGTSSASS--STSARQRRRQS KEQD-----------------------------------EVRRS-RDVGLIDKENIPSGFSSLEDCILSAQEVEKLYENT SGCVGERG-KPKRQKSSSKLSELNENQDG--LVNMESLNSTPSHERAG-PDDVELMSDE--SKENEKDGRHTQ------- ---------------HFENPTMKIQEHSGITDTKLQRT-----------------------------------QDAD-EQ QESFVSEVPELDLTALCDE----KSWE------------------------------------EPVPTFS-WQQENVDSD EAHLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLTPRMRQRSNTLPKSFGSQLEKEEEKKQE---LMD----------------- KVIKPSVEATLESIQRKLQEKRTETSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEDEGSEDDSNTKP -DFTVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EQ KKRIRKKLRDFED--------NFFRQNG--RSVQKEDRTPMAEEYNEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Bos_taurus_FAM13A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------MACEIMPL-----------------QSS-QED ERPMSPFYLSS---AHVSQVS--SVSSTGELLERTIRSAVEQHLFDVNSSGGQSSEDSESG-ASSSS--STSTKQRRRQA KEQD-----------------------------------ESRHS-RDVGRLNKENIPSGFSNLDECMLNACEVEKLYENT SGYIGERG-KPKRQKSSSRLSELNENQDG--LVNMENLNPTPSHERTG-SDHVELISDG--SKENEKDGRQSQ------- ---------------HLENPTMKIQEHPSLPDSKLQRT-----------------------------------PDAD-DQ QESFVSEVPELDLTALCDQ----KSWE------------------------------------EPIPAFSSWQQESVDAD EARLSPQAG-RLIRQLLE-----EDSDPMLSPRFYAYGQSRQYLDDTEM--------------------PPSPPNSHPFM --RRRSSSLGSY---------------EDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLPPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVD----------------- KAIKPSVEATLESIQRKLQEKRAETSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVSKNE RQVMKPLYDRYRLVKQILSRAS------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDNYTKP -DFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Equus_caballus_FAM13A -----------------------------------QSKAAVRLKEDMKKIVAVPLNEQRN-------------------- --------------STYKKLFGVSLQELQQ-QGLTENGVPAIVGNIVEYLTEH-GLSQEGLFRVNGNVKVVEQLRLQFES GAP----------------------------------------VELGRDGDVCAAASLLKLFLRELPERVITAAVRPRLI RLFQD---DRHDAQ-ESRLRDLIRELPDTHYCLLKYLCQFLTEVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGVKEQD LCNKIMAKILENYNTLFEVEYTEN--------DNQR--CESLAR------------------------------------ --------------------LIIVKEASCQNSLP-------------------------MLLTKDLEREMQKPCPKTRIP KSRSEGSIKAHRVPQPELSDGVPQVSLRLSRRK------PCWDDMNSAEDASSAKL-----------------VSSSQED ERPMSPFYLS----AHVSQVS--NVSTTGELLERTIRSAVEQHLFDVNSSGGQSSEDSESGSSSASS--TTSTRQRRRPS KEQD-----------------------------------EVRCG-RDLGLINKENIPSGFTNLDDCILNAPEVEKLHESA SGSIGERG-KPKRQKSSSKLSEHNENQDG--LVNMESLGSPPSHERTA-PDDVELMSDE--SKENEKEDGHTQ------- ---------------HFESSTMKIQEHPSLPDTKLQRT-----------------------------------QDAD-DQ QESFVSEVPQLDLTALCDE----KSWE------------------------------------EPIPAFSLWQQGSVDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------DDEQ-EDLTPAQLTRRIQSLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLSPRMRQRSNTLPKSFGSQLEKEEEKKQD---LVD----------------- KAIKPSVEATLESIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEE-EGSEDDSNSKP -DFTVTLKTDFSARCFLDQFEDDADGFISPMDEKMP---------SKCSQDTGLSNLHAASIPELLEHLQEMR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMTEEYNEYKHIKAKLRLLEVLISKRDTDSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Myotis_lucifugus_FAM13A -------------------------MFSNTYILIQQSKATVRLKEDMKKIVAVPLSEQKN-------------------- --------------STYKKLFGVSLQDLQQ-QGLTVNGIPAIVGNIVEYLTKN-GLTQEGLFRVNGNMKVVEQLRLKFES GVP----------------------------------------VELREDGDVCAAASLLKLFLRELPESVIPAALHPRFL QLFQD---DTNDAQ-ENSLRALIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLECMKEQD LCNKIMATILENYNTLFEVEHTGN--------DNQS--YENPTK------------------------------------ --------------------LIIVKEASYKNSTP-------------------------ILLTKDLERDVQKPSPKTKIP KSKSEGSLQVYRVPQPERCDGAAQVSLRLSRRK------PGWGDMNSAEDTSGATL-----------------VSSSQED ERPLSPFYLS----ARVSQVS--SVSTTGELLERTIRSAVEQHLFDVSSSGAQISEDSESGTSLAPS--TASARQRRRQS KEQD-----------------------------------EVRRG-RDMGLINKENIPSGLSNLDDCILNAQEVESLHENT SGYIGERS-KPKRQKPSSKLSDLNENQDC--LVNMESLNSTPSHESAR-TDHIELMSDD--RKENEKDSGHSQ------- ---------------HFESPTMKIQEHPSIPDTKLQRT-----------------------------------PDAD-TP QESFVLEVPRLDLTALCEE----KSWA------------------------------------DPMPPLSSWQQENGDSD DAPLSPPAG-HLIRQLLD-----EDSDPMISPRFYSYGQSRQYLDDTEV--------------------PPSPPNSHSFM --RQRSCSLGSY---------------DDEH-EDLTPAQLTRRIQSLKKKIRKFEDRFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLTPRLRQRSNTLPRSFGSQLEKEDEKKQE---VVD----------------- KAIKPNVEATLDSIQRKLQEKRAESSRPEDI---------------KDMTKDQIANEKVALQKALLHYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TMPIMGS-----PSSKRRSPLLQPIIEGETAFFFKESKEEEEGSEDDSNTKP -DFRVTLKTEFSAHCFLDQLEDGADGFISPMDDKMP---------SKCSQDSGLSNLHAASMPELLEHLQEMR-----EE KKRIRKKLREFED--------NFFRQNG--RNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDADSKSM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Gallus_gallus_FAM13A --------------------------MGAGALAIRQSKPAVRLKEDMKKIASLPLNKQKD-------------------- --------------ATRPKVFGVSLLELQQ-QGLSKNGIPVVVWNIVEYLTQH-GMTQEGLFRVNGSMKTVEQLRLQYER GEE----------------------------------------VELVKDGDVYSAASLLKLFLRELPDGIITSALHSKFI QLYQD---GRNEVQKERNLKELLKELPDAHYCLLKYLCQFLIKVAEHHVENRMNLCNLATVFGPNCFHVPSGFEGIKEQE ICNKIMTKMLESYNTLFELEGLKK--------DEEKPVCEELAR------------------------------------ --------------------IILVKVTKS--------------------------------------------------- --TREGSSRTHLVPQPGLSVGTPQVSLRLTDSS------SCLKEMDLTDEISFVNTGA--------------FFFSSQED ERPMSPFYVS----THVSQVS-SNIPATGEYLEKTIRSAVEQHLFDVHGSGGQSSEDSESGTSSASS--NVSARQRRRQH KEQE-----------------------------------EARRN-RDMEVINKENIPSGFSSLEDCILTTQEVEKLQDNS SGYLNERN-KPKRQKSSTKLSELNDNQDS--PVSMESFSSSRPIDRTG-PDDMEVLSEE--SKESENDEVFFRP------ ---------------SQQPSSMKIQEHPSIPENKLQRN-----------------------------------QDAD-DQ ENSFVSEVPRLDLTTLCDD----NNWE------------------------------------EPIPALSSWQRDGLDSE EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSQQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------EDDR-EDLTPAQLTRRIQGLKKKIRKFEDKFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLGPVVRQRSNTLPKSFGSQLEKEDDKKQD---LSD----------------- KSAKPAVEVTLDSIQKKLQEKRTETNRPEDI---------------KDMTRDQIAAEKVALQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLVKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEEDSNVKP -DFTITMKTDFNVRSFLDQLEDDADGFVSPVDDKIP---------SRSNQDMGLSNLHEASIPELLEQLQEVR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKQIKAKLRLLEVLISKRDISSKIM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Taeniopygia_guttata_FAM13A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --FLD---SRNDMQKESYLKELLKELPDAHYCLLKYLCQFLIKVAEHHIENRMNLCNLATIFGPNCFHVPSGFEGIKEQE ICNKIMTKILENYNTLFELEGLKK--------DEEKPVCEELAK------------------------------------ --------------------IILVKVSISNISFSH------------------------SRSIIQTYFRLQFRNLLDKWK ANSLEPSSQMCLLPQPGQSDGIPQVSLRLTDSA------SCGKEVDLADEISFVNN------------------DVSQED ERPMSPFYVR----SHTVTLK-PRK-ATQWYLEKTIRSAVEQHLFDVHGSGGQSSEDSESGTSSASS--NVSARQRRRHH KEQE-----------------------------------EARRN-RDMEVVNKENIPSGFSSLEDCILAAQDVEKLQDTS SGYLSERN-KSKRQKSSTKLSELNDNQDS--PVNMESFSSSKPIDRT--ADDMEILSEE--SKGFGFGAGSIR------- ---------------IWLTSSMKIQEHPSMPENKLQRN-----------------------------------QDAD-DQ ENSFVSEVPRLDLTSLCDD----SNWE------------------------------------EPIPALSSWQRDGLDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSQQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------EDDR-EDLTPAQLTRRIQGLKKKIRRFEDKFEEERKYRPSHSDKAANPEVLKW TN----DLAKFRKQLKESKLKISEE--DLGPVVRQRSNTLPKSFGSQLEKEDDKKQD---LSD----------------- KSAQPAVEVTFDSIQKKLQEKRAETNRPEDI---------------KDMTRDQIAAEKVALQKALLCYEGIHGRPVTKNE RQVMKPLYDRYRLIKQILSRAN------TIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEEDSSVKP -DLTITIKTDFNVRSFLDQLEDDADGFVSPVDDKMP---------SRSSQDMGLSNLHEASIPELLEQLQEVR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKQVKAKLRLLEVLISKRDISSKII-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Anolis_carolinensis_FAM13A --------------------------MGAGALAICQSKSAVRLKEDMKKIACAPLKGQRG-------------------- --------------IPVRRVFGTNLQELQQ-QGLSKNGIPDVVWDIVEYLTRH-GLKQEGLFRVNGSLKTVEQLRLKYES GEE----------------------------------------VDLVADGDVSSAASLLKLFLRELPDRVITSAAHPKFM QLYQD---SRQHGLNANSLRELLRQLPEVHYRLLKYLCHFLRRVAEHHSENKMNISNLATVFGPNCFHVSPGFEGMKEQE TCNKIMAYMLENFSALFEWEHMKK--------ENEMHPCEELSK------------------------------------ --------------------IILVKEASCKQNLPV------------------------ILTSVER--ETPKRSPRNKIT KCKQEGSSLAFLMPQPRLSDGIPRVSIHLTDS-------SCPEEMDLADDISFMSSTA--------------FFTSSQED ERPMSPFYLS----AHVPQVNNNSIPATGEFLEKTIRSAVEQHLFDVHGSGGQSSEDSESGTSSTSS--NVSARQRRRHH KEQD-----------------------------------EARRT-REREVINKENIPSGFSGIDECMLTAQEVEKLQENS SGYVGERS-KPKRQKSSSKLSELNDNQDT--LLTMETFAPLRPVDRTGPDDDMEVFSED--SKDSESDGDIFR------- ---------------HSQCLTMKIQEHPSLPETKLQRN-----------------------------------QDPD-GQ EETFVSEVPRLDLTALCSD----NNWE------------------------------------EPVPAFSSWQRDGLDSD EARLSPQAG-RLIRQLLD-----EDSDPMLSPRFYAYGQSQQYLDDTEV--------------------PPSPPNSHSFM --RRRSSSLGSY---------------EDDR-EDLTPAQLTRRIQGLKKKIRRFEEKFEEERKYRPSHSDKAANLEVLKW TN----DLAKFRKQLKESKLKMSEE--DLVPVMRQRSNTLPKSFGSQLEKEEEKKQD---VPD----------------- KSSKPAVEATLETMQKKLQEKRAEANRPEDI---------------KDMTRDQIAAEKVALQKSLLYYESIHGRPITKHE RHMMKPLYDRYRLVKQILSRAN------SIPIIGS-----PSSKRRSPLLQPIIEGETASFFKEIKEEEDGSEDDSNTKP -DFTVTIKSDFNVRSFLDQLEDDTDGFVSPVDDRIP---------SRGGQDMGLSNLHAASMPELVEQLQEVR-----EE KKRIRKKLRDFED--------NFFRQNG--RNVQKEDRTPMAEEYNEYKQVKAKLRLLEVLISKRDFGSKIM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Xenopus_tropicalis_FAM13A ----------------------------VGPMTTCKSKAAIRLKEDMKKVVSRPARGQPP-------------------- --------------IQCKKVFGVQLKDLHM-NGLVTEGIPTLVWNIVEYLRTI-GMDQEGLFRVNGNVKMVEQLKLKYES GEQ----------------------------------------PILGEEMDVHSAASLLKLFLREMPDGVITTALLPKFI EGYQS---CGSDTQRESSLKDLLKQLPDSHYSLLKYLCHFLTQVVEHCGENRMNVHNLATVFGPSCFHVSPGPECMMQQN ICNKIMERLLEDYTKFFECEAIKK--------AQLP---EETAR------------------------------------ --------------------IITVKEVYYINISP-------------------------VRPTTYEENEATGSSPRTKLY KPKTKTLIQEFSVLTPKTSDGTPQPSLHFSYKDH-----KCILDMEYSTGDIHSVL-----------------LCSSQDD ERPMSPFYVS----GHVAQVN---VPADRELLERTIRTAVEQHLFDVLGGGTQSSEESESGTSSPST--SSSARQRRRHL KEQD-----------------------------------EIRKKPRDMEIINKENIPSGCGSFDACGL-AQEAEKLQETC SGYTEERS-KPKRQKSSSKLSELNENQDS--PLSAENFVTSRSVDIQE-LTGMEVLAESPSSKEMDSDQEYSR------- ---------------ISPPAKMKIQEQKNNSESRPQRR-----------------------------------LEAE--- -ESFVPEVPRLDLTSLCDD----NNWE------------------------------------EPVPALTSWEQDGRDSD EARLSPQAG-RLIRQLLE-----ADSDPMLSPRFYAYGHSQQYLDDPEV--------------------PPSPPNAHSFM S-RRRSSSLGSH---------------EEDRDEDLTPAQLTRKIQSLKKKIRKFEDKFEEDRKYRPSHRDKATNPEVLKW MN----ELAKFRKQLKETKIKLSED--DLVPQMRQRSNTLPKSFGSQLDREEEKKPE---TVE----------------- KPAKPSMEATMEAIQKKLQEKRNEVNRPEDI---------------KDMTRDQIAAEKVSLQKALLYYESIHGRPVTKNE RQVMKPLYDRYRLFKQILSRAN------TIPVIGS-----PSSKRRSPLLQPIIEGETASFFKEVKEEEEGSEDDTNGNT -DFTVTMKPGFSVRTFLEQLDDDADGFVSPVDDNIP---------SKSSQDLGLGNLHSASIPELLEQLQEAR-----EE KKRIRKVLRDFED--------NFLKQNG--RNVQKEDRNPMAEDYIEYKHVKAKIRLLEVLINKRG-VSQTM-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Danio_rerio_FAM13A --------------------------MGAG--AICHNKAAVQIKEDMKWMVQMPTIRAHP-------------------- ---------------QRRKMFTVSLLELRD-LGLLEDEVPAVVRRLVEHLQKQ-GLRQEGLFRVNGSVRTVESLRQRFDG GEA----------------------------------------VDLDQEVDTFAVASLLKQFFRDLPEGLIHQSIHKPLI QLYQE---SSEADF-CHDLRELLRQLPDLHYSLLQYLCYFLSQVEQEHEHNRMTASNLATVFGPNVFHVSSGFDGIREQN ICNNIMAKLIQNYSAVFESQLEEK--------QTEEESSNIIMVKEAKTNTESTEASLYTPVPQTQTPRVKKMKVTQCTP VENTDSSRKQLSPDNPASTPRKKKVTQCTTVDSAD------------------------LSRENESGADDPTPTPRKKKV KKIKTEAMSRSIPQPTPSGDPVSRPSPHLPDRSS-----GAGDQFHLHSPDGSFSPSADSMNVTMSPARSTGTFNSPQED ERPISPFYISS---EISPEHSRS---DLTNFLEKTIRSAVEQHLFMHAGQSSESSNPTLHSSSP-----ATTARERRRHQ REQQ----------------------------------------ESFRVEGDKENVPSPGVRVTE--------DGDRSLL LLPLTHELKKNKKPKHSPTLTELSDNQD--------TPASMEFQGPSGAYNRNATENMESSDYRGNHVKDRSCT------ ---------------YFQTPAMKIQEALSGAEP----------------------------------------------- ----CDDVPRLDLSTLTDD----NNWA------------------------------------EPVPAYSSWQRESMDRD EARLSPHAGGKLIRQLLE-----EDSDPMVSPRFYGYGDGHQYLDDTEV--------------------PPSPPNAHSFV S-RRRSSSLGSC---------------EDER-EELTSAQLSKRIHVLKKKIRRYEEKFEEERKYRPSHGDKAGNPEVLRW MN----ELTRLRKDLKDHKLLKSEE--DLTPIPRQRSNTLPKSFGSQLEKKTPET------------------------- KAPKPPVESTLETVTNKLQEKRKEAGRPEDI---------------KDMTREQIGAEKVAIQKALLYYESIHGRPITKNE RQVMKPLYDRYRLVKQILCRAS------AIPVIGS-----PSSKRRSPLLQPIIEGVPALFFSDTKEEEDGSDDD-DTRT -QFTVTVKPELSMLGLLDQLDEDADGFISPVDELSP---------SKNTTDMRLSNLHAATMQELVEELQEAR-----EE KKRIRKNLREFED--------QFFKQNG--RNVQKEDRSPLAGEYNEYKHIKAKLRLLEVLISKQDSSKFI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Takifugu_rubripes_FAM13A --------------------------MGAGALTICHNKTAVLVTEDMKKMVQIPILRPR--------------------- -------------PAKNTKVFGAPLSELQD-RGLVEDGVPVVLRRLVEHLRRH-ALRQEGLFRVNGNVRAVETLKQQLEA GED----------------------------------------LD-LSGSDSCAVASLIKQFLRDLPGGLVSTRVQQALI HRYHE---CGDDIT-CSDVRDLLQPLPDMHYHLLSYLCRFLTLVESNHKENRMTAFNLATVFGPTVFHVSPGIDAMKDQN VCNKIMVKLIQNCTSIFESSLDAE--------SSPERST----------------------------------------- ------------------IIVVKVLFFLLS---LL------------------------ICHSRILDKQAQSGRPKNTYD IIKTQTKINGVRTLYPLGVSTPRLHLSSVAKKLF-----DELQSAE--SAIGISSIP------------------SSNYI ELSTNPLVLHSSSPHLSPARSRPDVVNER-FLNGTISSVVEQHLFSVNPTRGQCSGDCQLTPRPPTPGVSTSARQRRRQR REQHFL---------------------------------SRNRIAPEQAEPNKENIPFREARIWD-CAGDEAGGDSGSIS NSSSGHEEPAPQPRKHSPTLVPLSNNQD---------ARADEDCVGERTGTDPMETFQKGGKASKRGTSHTAHT------ ---------------RSTNPAMKIQEPPVSCDAGRVG-------------------------------------GGDPDC DKPSCEDVPRLDLTALTEE----NHWGA-----------------------------------EPVPAYSSLQRENTDLE EPRLSPHAGGFLIRQLLE-----EDSDPMVSPRFYAYGQCQQYLSDTEV--------------------PPSPPNAHSFI S-RRRSSSLGSC---------------DDEK-EELTTAQLTKRIHVLKKKIHRFEEKFEEEHKYRPSHGDKAANPEVLRW VN----ELSKLRKDLKEHKLMKSEE--DLQPLTRQRSNTLPKSFGSQLEKKPAQE------------------------- KVPKPPAETTLESILKKLQEKRGEVNRPEDI---------------KDMTREQIGAEKVALQKGLLYYESIHGRPVTKNE RQIMKPLYDRYRLVKQILCRAS------TIPVIGPKSGF-SSSVNPSPVVKELKNGKVVDVFLLLQEEEDGSEDDGDSKT -QFAVSVHTDVSVLSFLDHIEEDVDGFISPVDELS----------TTKTTDMRLSNLHSATTQELVEQLQEAR-----EE KKRLRENLKEFED--------QFFRQNG--RNVQKEDRSPLAAEYSEYKHVKAKLRLLEVLISKRDATKFI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Tetraodon_nigroviridis_FAM13Aa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------IYVR-------------------------------------LFSSL------------------RPRGE ERPISPFYVSP---HLSPTRSRPDVVGYARFLNRTISSVVEQHLFSTNPTRGQSSGDPDLTPSPPALAVRTSARQRRRQR REQQ------------------------------------EELLRRRGAGTNKENIPSSEGSLREKEAG-----SSSADL LGGDGERTPKPRK--HSPTLVLLANNQD--------THTISLEELNTLSPDETPRIFSPLAETPTETSFKKKTS------ ---------------YCQLPVMKIQEPPVTCDAGRVGG-----------------------------------GGGDADC DKPSCEDVPRLDLTALTEE----NNWG------------------------------------EPVPAYPALQGESVDRE EPRLSLHAGGFLIRQLLE-----EDSDPMLSPRFY-YGQCQQYLSDTEV--------------------PPSPPNAHSFI --RGGSSSLGSC---------------DDEK-EELTTAQLTKRIHVLKKKIHRFEEKFEEEHKYRPSHGDKAANPEVLRW VN----ELSKLRKDLKEHKLMKSEE--DLQPLTRQRSNTLPKSFGSQLEKKPAQE------------------------- KVPKPPAETTLEGILKKLQEKREEVRRPEDI---------------KDMTREQIGEEKVALQKGLLYYESIHGRPVTKNE RQMMKPLYDRYRLVKQILCRAS------TIPVIGS-----PSSKRRGPLLQPIIEGETALFFDDIKEEEDGSEDDGDSKT -QFSVTR-ADLSVLSFLDHAEEDADGFISPVDELTA---------SKNTTDMRLSNLHSATTQELVEQLQEAR-----EE KKRLRKNLKEFEE--------QFFRQNGSHRNVQKEDRSPLAAEYGEYKHVKAKLRLLEVLISKRDSGTKSY-------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Gasterosteus_aculeatus_FAM13A --------------------------MGAGALTICHNKTAVQIKEDMKKMVRTPALRPLAA------------------- -------------TAAYTRLFGVSLFELRE-KGLLEDGVPLVLRRMVEHIREH-ALHQEGLFRVNGNVRAVETLKQRLES GED----------------------------------------VDLLAESDSSTVASLLKRYLRDLPMGLVDPTVQQALI QHYQE---CGDDVS-SSDMRDLLQQLPDVHLSLLRYLCHFLTLVDRNHKENRMTALNLATVFGPSVFHVGPGLEAMRDQN ICNKIMVKFIQNYSHLFEIAGDTE--------GRADKPS----------------------------------------- ------------------TFVTLKEVNMTDAD--T------------------------MKSPGDLDANPPTPAPRTKVT GAKGEGSNQGHVYVQDMVKPSAEMFTVQCATNSD-----CSEDTNKVYTHIVSYSYY------------------SSDEE DGPISPFYMSF---HFGEYQNIS--LGTFSFLDRTIRSAVVQHLFDGNPSGDQSSEDCESTPRP--APPRPSARQRRRHH REQQ------------------------------------EEGLRLKGR--NRSVFNSLKECVCERPEANHMERSDRECC LPETRVWYQRLNK--TKNIHMIHYNMEK--------IASCRRAQAEETGPRRPVDTFSIHDLLSGFDQIDKNAP------ ---------------RIWSRVMKIQESPVACDAGRVGG-----------------------------------GGEARGS DQ-EREEVPRLDLTALTEE----NNWG------------------------------------EPVPACPQMQRESMDRE EARLSPHAGGRLIRQLVE-----EDSDPMLSPRFYGYGQCQQYLDDTEV--------------------PPSPPNAHSFV S-RRRSSSLGSC---------------DDDR-EELTSAQLTKRIHVLRKKIHRFEERFEEERKYRPSHCDKAENPEVLRW VN----ELAKLRKELKESKLMKSEE--DLPPLTRQRSNTLPKSFGSQLEKKPPQE------------------------- KAPKPPVESSLETILKKLQEKREDVNRPEDI---------------KDMTREQIGAEKVALQKALLYYESIHGRPVTKSE RQIMKPLYDRYRLVKQILCRAS------TIPVIGS-----PSSKRRGPLLQPIIEGETALFFDDIKEEEDGSEDDGDSKT -QFSVTAPPDASVLGFLDHAEEEADGFISPVDELSP---------SKHMTDMRLSNLHAATAEELVEQLQETR-----EE KKRLRKNLKEFEE--------QFFRQNG--RNVQKEDRSPLAVEYNEYKHVKAKLRLLEVLISKRESTKLT--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Oryzias_latipes_FAM13Aa --------------------------MGAGAMTVCHSKAAVQVKEDMKKMVQIPILRSRAV------------------- -------------AAQHTKLFGASLLELRE-QGLEEEGVPFVVKRMVEHLAKH-ALHQEGLFRINGNVRAVETLKLRLES GDD----------------------------------------VDLLSESDSSTVASLLKKYLRDLPGGLVDSAVQQALI QNYRE---NGENGS-CSDLSVFLQQLPDVQHKLLRYLCHFLTLVEGNHKHNLMTADNLATVFGPNVFQVAPGFESMKDQY TCNKIMAKLIQDYRCIFEVSFLVW--------EHLLCLC----------------------------------------- ------------------LRAKHIIYNLQYKDEAP------------------------LCLSGCITAQLSHECPGSKIT HKKKSGRT-EAHLIQSGRASDPKPCVSVLLAGEQ-----ACRTGSD--DSVSSVLSP------------------SSQDD DRPISPFYMSN---HLPPVRCKPGPTKS--FLDQTIRSAVEQHVFSANTIADQPQESCESTTCPSSPRVKPTARQRRRRQ REQQ-----------------------------------EEGLQEKNRTENNKENIPSSAGSSSNSLVEDTVGSEVSPGS QSGTCEQIPRSRKSSHSPTTAQLIENQAGHTLINIKKVGSFREAVGEGPDENHMDTLRKGNTEEWEHLKHFSDE------ --------------------GMKIQESPVACDTARVGGVEV--------------------------------RSSDPDR DKTSCEDVPRLDLTALTED-----CWG------------------------------------EPAPAYS-LHRESMDRE EARLSPHAGGRLIRQLLE-----EDSDPMVSPRFYAYEHSHQYLDDTEV--------------------PPSPPNAHSFV S-RRRSSSLGSG---------------EDDR-EELTSAQLTKRIHILKKKIQRFEDRFAEDRKYRPSHSDKVGNPEVLRW VN----ELARLRKELKEQKLMKSEE--DLPPVTRQRSNTLPKSFGSQLDRKSQQE------------------------- KAPKPPVESTLESIEKKLQEKRAEVNRPEDI---------------KDMTRDQIGLEKVALQKALLYYESIHGRPVTKSE RQIMKPLYDRYRLVKQILCRAT------TIPVIGS-----PSSKRRGPLLQPIIEGETALFFDDIKEEEDGSEDDGDTRT -QFKMTVESDLSMLSILDHMDEEVDGFVSPVDDL------------EKTTDMRLSNLHSATMQELVEQLQEAK-----EE KKRIRKNLKEFED--------QFFRQNG--RTVQKEDRSPLAVEYHEYKHIKAKLRLLEVLISKRDAAKFI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Branchiostoma_floridae_FAM13A ---------------MELLTFFTVSIVCVYFYVQALDVPVESRMGKVKKFMSSPLSRKK--------------------- -------------LSPGAKLFGAPLEAVPRVT---DLSIPSIVKKVVDFITMH-GIGHEGIFRVNGNTKVVEKMKTSFDK TGD----------------------------------------ANLEEFGDVFSVASLLKMYLRELPDAVIPESLHSQFV AVQEDF--LNDPVECRRQFRLLIDKLPPEHFCLLKYLIQFLVRVSCQQDTNKMGSMQLAIVFGPNLFKCPDGVAGLREQG ITNQIVKRFIDDYDELLLEEGETSPYSSKCIQGAIEDQPKVYNS------------------------------------ ---------------------AKYEDSNHN-----------------------------------VQINIVDAAGTSKDY LRASDATTYS-------------------------------------PIVGSFVQEVVEQTIHETVTKHMFGNS------ -----------------------------SSSEGSAQVELDTTLQGLDVSLN--------DPLDSPKDAPVPTPRRRRRQ --------------------------------------KKLEEDRRHDTESSEECSPEDSNNRG---------AVDKIDS LQAAEEEDISATLSFREKVKIFDVDQSSAPVGDDRPATRPRRQRPNSQAFELFETQEPHKELTVNRASAPKRRK------ -----------------PSRKSKGEDHEEDTFVQRISE--------------------------------------EDIE EVKMEEPPKRAQPAKMEDTSPEDIEN--------------------------------------IVPPLDLASLHEHGDG DEPIPAGMWHHSLKEEEE--ATLSPRSTKLKKRQHSTGHSSPIPIHHHGL-------------------MEADFEAPLSP SVLRPLPFLQSAPADVDIPPSPPASHMHSMTTEDKEIRDLTKKIHSLKKKVRRFESQFEEEKGYRPSHADKMGRTDIRKI VN----DLSKAKKDLKEERHSLSKT---LPTKLDYPFGGGGGDPDSPLS------------------------------- -----ALRGSLNHALHILAEKREDADRPEEL---------------ERLTMDELREEKVAMQKELLHLESTHGRPTSKVE KDIVRPLYERYRQIKKFLS---------KPPSLGD----LRNLETIEEG----------EMMEFQQTPPKDDGFGTTMTT NDFTVTQNFGLLQETR----EEDGEEEADQNGEGAN----------ENEFT--SETLHQASLQELLDHLKKLR-----LE KKRLRAVLKRFED--------DFFTQNG--RKIAKEDRGDMSSEYKAYKTVKQSLKLVEALINKKDGSKTM--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Strongylocentrotus_purpuratus_FAM13A ----------------------------------------------MQKILRSPASIRR--------------------- -------------KVVN-KMFGVPLKELCRYGPN-GIRIPELLQKIIEFIKMH-GIGHEGIFRINGSSKIVEKLRMQYDR HGN----------------------------------------ANLEEAGDVMAVASLLKLFFRELPDPVVIGQLHPQFL TVQEEF--QYNKEESLKQLKNLLQQLPEENFLVLRYLCSFLIKVIHHEDTNKMNSMALAIVFGPNLFRCADGIQGLREQG QTNHLVRLFIDKFDFLFGHDG--GSYSPPSPVNAINGSGRVWNS------------------------------------ ---------------------KRIEVQAAKEKKSPPFT---------------PLPHAQYMKQRRTKLALQEEVDLNSNY SEVSKEDSSSGSPQNHGYLSIPDGEYEERAFSPFTLDSDQGTSAAPSPVTSSITSELVERTIQESISQHLFGARGSPRLD LSPRQETPVAMPRKKHQKKNQDSSSFNRRSNSESSLEHLVNSFAEREGISVKNRAQQFSDDTLVSSKSHDQSHPVRRKGR PASKAFDIFESQGIIIG---------------------QRLVDSSSVSEGLSREGTLTDVTHDGESELDSVKRNSGTLNS LTAGRVAPPKRRSPTKKHRSAKGEHSLDSPNGKEKAAKRSNNSDFRTQNHDVWLRQNGDGQRSPSNGGSRNPREGGLWGV HNNIDTPQHREQPVPQPRTRRGKAKDDEMDEASRRRTEGVSEGHGDRRRTEGDERRHDGGEARRMNERGGDGRRRDEEMR DGRMEDELRRLKGEDRKNPSPNSLRGQ-------------------------------------VVPPLDLAGLHVDTDG HEAVLAWQSQQAAPKSGGGGGGEGEGQSGMEGGPQTLSRLEKLQTITSLL-------------------QHEPYDAPLSP RAKDAPPTFGSS--------SKRSESSLDEEDQVSIIKRLTRQVRSLKQKIKQYEEEFESQYHAKPSHTEKLSQPEIRKM IG----ELKRATKQLKALKTEAKESKNPLHSTLPARLSPNGVEEGSHLS------------------------------- -----GLKEALNLAQKRLQEKRDDAKRGFDV---------------LEMNQDEVREEKVAIQKALLQLESKYGRPTSRAS KEVMKPLYDRYRTLKKLMKNKELRRSISEEASPSD----LNTIEEHVETRDFIPKHMGFVHSKYDMEGEEENEEDDMFCT TDFRVTQMVSPSQRSSGRSPSDHDDVCVSPNDSYRN----------DSPFSPASASFHEASLEELQTRRDQSL-----DE KRRLRRVLKDFEE--------NFLHETG--QRVQKEDRSPMEMEYVQYKV------------------------------ -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Homo_sapiens_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTAT-------------------------- STHISPISILPA---------------STDILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSVVCNNEAESIHCDG E------------------------------------------GSNNQIDIADDI-INASESNRDCSKPVASTNLDNEAM QQDCVFENEENTQ---SVGILLEP--------------CSDRGDSEDGCLEREEYLLFD--SDKLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAAC-VSIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKNSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQ----------------- KEKKPSKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSS--- -ELGDMLKTAVQVQ----SSLENSESDVEENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Mus_musculus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SDLASKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLL QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGVEKSAGMPEVLQLR----------------------MTEN-LLDSDSVTAS-------------------------- -------------------------------------------------------------------------------- --------------------------------------------TRIDAAAAT-T-TNASDGNIKCSKPVAGTTADNEVM QQDFVFEDQKNNE---SVGILLEP--------------CSDHGDSEDGCPERKEYLLCD--SDKLPHLILDS-------- -----------------SSKIRDLNANTELEVTEGQSV--------------------------------------GVQG EAAC-IQIAQLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDC-ESG EAQLSPQAA-RMTHHPLG-----EDCPPVLSHRSLDFGQSQRFLHDPEA--------------------LDFSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKNSDG--EFAPQTRPRSNTLPKSFGSSLDHEDGESEGEPRVIQ----------------- KEKTPSKEATLELITKRLKENRAERHLPEDI---------------KKMTKDHLIEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVSLSS--- -ELGDILSTSVHTQ----SSLENLESDAEENQEK-------------LARDLCLSSTRAASVPELLEQLWKAR-----AE KKKLRKMLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYKEYKRIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Pan_troglodytes_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTATT------------------------- STHISPISILPA---------------STDILERTIRAAVEQHLFDLQNSIDHD----LKNLQQQSVVCNNEAESIHCDG E------------------------------------------GSNNQIDIADDI-INASESNRDCSKPVASTNLDNEAM QQDCVFENEENTQ---SVGILLEP--------------CSDHGDSEDGCLEREEYLLFD--SDKLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAAC-VSIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKNSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENGDEPKVIQ----------------- KEKKPSKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSS--- -ELGDMLKTAVQVQ----SSLENSESDVEENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Gorilla_gorilla_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYDFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTAT-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------T---SVGILLEP--------------CSDHCDSEDGCLEREEYLLFD--SDKLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAAC-VSIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKNSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQ----------------- KEKKPSKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSS--- -ELGDILKTAVQVQ----SSLENSESDVEENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Callithrix_jacchus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSPD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSADSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEE-DEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTAST------------------------- STHISPISILPA---------------STDILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQNAVCNKEAQSIHCDG E------------------------------------------GSDNQVNIADDI-INASESNRDCSEPVASTNLDNEVM QQDCVFETEENNQ---SVGILLEP--------------CSDHGDSEDGCPEREEYLLFD--SDKLSHLILDS-------- -----------------SSKICDLNANTETEVPGGQSV--------------------------------------GVQG EAAC-VHIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KEEKRDDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKSSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPRVIQ----------------- KEKKPTKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPILGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSS--- -ELSDILKTAVQIQ----SSLENSESDIDENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Pongo_abelii_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQ----------------------------------------------------------------IYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTATT------------------------- STHISPISILPA---------------STDILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSVVCNNEAESIHCDG E------------------------------------------GSNNQVDIADDI-INASESNRDCSKPVASTNLDNEVM QQDCVFENEENTQ---SVGILLEP--------------CSDHGDSEDGCLEREEYLLFD--SDKLSHLILDS-------- -----------------SNKICDLNANTESEVPGGQSV--------------------------------------GVQG EAAC-VSIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHSLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKQKNSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQ----------------- KEKKPSKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIREEEEDGVNLSS--- -ELGDILKTAVQVQ----SSLENSESDVEENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Macaca_mulatta_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDMPEVVQLR----------------------MTEN-ILESNSVTAST------------------------- STHISPISILPA---------------STDILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSVVCNNEAESIHCDG E------------------------------------------GSNNQVDIADGI-INASESNRDCSEPVASTNLDNEVM QQDCVFDNEENNQ---SVGILLEP--------------CSDHGDSEDGCLEREEYLLFD--SGKLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAAC-VNIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEK--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKSSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQ----------------- KEKKPSKEATLELILKRLKEKRIERCLPEDI---------------KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSS--- -ELSDILKTAVQVQ----SSLENSESDVEENQEK-------------LALDLRLSSSRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Rattus_norvegicus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SDLASKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLL QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLDHVEELP EEGVEKSAGVPEVLQSR----------------------MAEN-TQESDSVIAT-------------------------- -------------------------------------------------------------------------------- --------------------------------------------ARVAAAAAAAT-TNASDGNTKCSKPVAGTTADNEVM QQDFVFEDQKNNE---SVGILLEP--------------CSDHGDSEDGCPERKEYLLCD--TDKLPHLILDS-------- -----------------SSKIRDLNANTELEVTEGQSV--------------------------------------GVHG EAAC-IQIAHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAA-RMTHHPLG-----EDCPPVLSHRSLDFGQSQRFLHDPEA--------------------LDFSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKNSDG--EFVPQTRPRSNTLPKSFGSSLGHEDSESDGEPRAIQ----------------- KEKTPSKEATLELITKRLKENRAERHLPEDV---------------KKMTKDHLIEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVSLSS--- -ELGDILSTAVHTQ----SSLENSESDAE---EK-------------LARDLCLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYKEYKRIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Oryctolagus_cuniculus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLKFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDMKEQE IVSRIMAGLLENYYGFFENEEEE--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEDEEDEKLEHIEELP EEHVEKSNEMPEEVQLR----------------------MTEN-VLESNDIMAST------------------------- SAHISSTSILPA---------------SADILERTIRAAVEQHLFDLQSSIDHD----FKNIQQQSLMCNNEAGSINCDG K------------------------------------------GSNNQVDITVDI-FNASKGDRGCSKPVASTNLDNEVM QQDCVFEDEENNQ---SVGILLEP--------------CSDHSESEDGCLDRKEYLLFD--SDKWSHLILDS-------- -----------------SSTICDLNANTASEVCGSQSI--------------------------------------DAQE EADC-VQIPRLDLKNVSDD----DKWE------------------------------------EPFPAFKSWQEDC-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLAHRSLDFGQSQRFLHDPET--------------------LDSSSKALSFA --RIRRSSFSS----------------KEEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKSSDG--EFVPQTRPRSNTLPKSFGSSLDHEEEENEDESRIIQ----------------- KEKKPSKEATLELILKRLKEKRAERCLPEDI---------------KKMTKDHLVEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPILGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVSLSS--- -ELSDILKTAVQAQ----SSLENSESDVEENQEK-------------LALDLRLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Canis_familiaris_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDLKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQAGSSVLHKLESGEQAFHEALEKGITAVKERRDVNELSEEEEEDEKLEQIEELP EEGAEKSSDMAEVVQLR----------------------MTEN-ILEPNSVTAST------------------------- SAHLSPISILPA---------------SADILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSLVCNNEAESINCDG E------------------------------------------GSNNQVDIADDI-INASESNRDCSEPVASTNLDNEVM QQDFVFEDEENNQ---SIGILLEP--------------CSDHGDSEDGCLEGKECVSFD--SDTLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAACGTQIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPET--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKFQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKSSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDESRVIP----------------- KEKKPSKEATLELILKRLKEKRVERCLPEDI---------------KKMTKDHLIEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYERYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVTLSS--- -ELTDILKTAVQAQ----SSLENSESDVEENPEK-------------LALDLRLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Felis_catus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDLKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSSDMAEVVQLR----------------------MTEN-ILEPNSVTAST------------------------- SAHLSPISILPA---------------SADILERTIRAAVEQHLFDLQSSIDHD----FKNLQQQSLVCNNEAESINCDG E------------------------------------------GSNNQVDIADDI-INASESNGDCSEPVASTNLDSEVM QQDFVFEDEENNQ---SVGILLEP--------------CSDHGDSEDGCLEGKEYVSFD--SDTLSHLILDS-------- -----------------SSKICDLNANTESEVPGGQSV--------------------------------------GVQG EAACGTQIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-DSG EAQLSPQAG-RMNHHPLE-----EDCPPILSHRSLDFGQSQRFLHDPET--------------------LDSSSKALSFT --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNNKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKSSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDESRVIQ----------------- KEKKPSKEATLELILKRLKEKRVERCLPEDI---------------KKMTKDHLIEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYERYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVTLSS--- -ELTDILKTAVQAQ----SSLENSESDVEENQEK-------------LALDLRLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Bos_taurus_FAM13B --------------------------IGSHGMALEKTALISGCKKDMRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDLKEQE IVSRIMAGLLENYYEFFENEEKENDKKRTIQISEISFLS----------------------------------------- ----------------------TLYFQSFIP---------------------------LMFRITYEQNIDKQKVKLIRGS RRTFEAKQSSNLVLKPKNSIFLPVFFLGLSTLKFCLFEFSSENSQLSAKKITLSLQMDVSPRS-------------QFYY SAHTSPISMLPA---------------SADILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSLVKPSQTSKNHKEK NQVKV--------------------------------------GTNEGMRIKRDNNINSINKLPNCSTNQQRIRSEHRHR FSGSLAKPKGQTPRNQSSEIHLKRNYLQRY---LLFRMFGIYEDAPPGDFKTMHLQRDGE-EQEISHKMFITSY------ ---------------LFSGKQHLAQLNSQYNFEELDSVP-------------------------------------SCFV TGFR--NLKCNSLCEIRTE----VCFP------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPVLSHRSLDFGQSQRFLHDPEM--------------------LDSSSKALSFA --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNGKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKTSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDDSKVIH----------------- KEKKPSKEATLELILKRLKEKRVERCLPEDI---------------KKMTKDHLVEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVCLSS--- -ELNDILKTAVQAQ----SSLENSESDVEENQEK-------------LALDLRLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLRDFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Equus_caballus_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EELWSANSLAAVFGPDVFHIYTDVEDLKEQE IVSRIMAGLLENYYEFFENEEED--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHIEELP EEGAEKSNDIPEVVQLR----------------------MTEN-ILEPNSVTAST------------------------- SAHISPISILPA---------------SADILERTIRAAVEQHLFDLQSSIDHD----LKNLQQQSLVCNNEAGSVNSDG E------------------------------------------GSNNQVDIADDI-LNASESNRDYSEPVASTNLDNDVM QQDFVFEDEENDQ---SVGILLEP--------------CSDHGDSEDGYLERKECVSFG--SGKLSHLILES-------- -----------------SSKICDLNANTESEVPGAQSV--------------------------------------GVQG EAAC-VQIPHLDLKNVSDG----DKWE------------------------------------EPFPAFKSWQEDS-ESG EAQLSPQAG-RMNHHPLE-----EDCPPILSHRSLDFGQSQRFLHDPEM--------------------LESSSKALSFA --RIRRSSFSS----------------KDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKW MT----ELTKLRKQIKDAKHKTSDG--EFVPQTRPRSNTLPKSFGSSLDHEDEENEDESRVIQ----------------- KEKKPSKEATLELILKRLKEKRVERCLPEDI---------------KKMTKDHLVEEKTSLQKSLLYYESQHGRPVTREE RHIVKPLYDRYRLVKQMLTRAS------ITPVLGS-----PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVSLSP--- -ELTDILRTAVQAQ----TSLENSESDVEENQEK-------------LALDLRLSSTRAASMPELLEQLWKAR-----AE KKKLRKTLREFEE--------AFYQQNG--RNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI--------- -------------------------------------------------------------------------------- --------------------------------------------------------------------------- >Loxodonta_Africana_FAM13B ----------------------------------------------MRKSSS--PSLSNCN------------------- -------------SVLANKIFGIPLDELQQ-GGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDN GEE----------------------------------------VDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLM QLSQD---YNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVEDLKEQE IVSRIMAGLLENYYEFFENEEEE--------FSS-NDLS----------------------------------------- ----------------------SITEQ--------------------------------VNELSEEEEEDEKLEHI