>Homo_sapiens_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGAPEGSGSNSSSSSSGGGGGGGGGSNSSSSSST------------------------- -------------------------------------------------------------------------------- -FNPQADTGEQPYEHLTAESF----------------------------------------------------------- -----------------------------------PDISLNNEKVLVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MTNPP ASSSSAPSPAASSAS----------------------------------------------------------------A SQSPPLSCAVPSNDSSPIYSAAPTFPT---------------------------------PNTDIFPEPQSQAFP----- -------GSAGTALQYPPPAYPA---AKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LGLGTPDQKPFQ---GLESRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKALNT------ ------SYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKSVVASSATSSL--SSYP SPVATSYPSPVTTSYPS--------PATTSYPSPVPTSFSSPGSSTYPSPVHSGFPSPSVATTYSSVP--PAFPAQVS-S FPSSAVTNSFS--ASTGLSDMTATFSPRTIEIC----------------------------------------------- ---- >Mus_musculus_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGTPEGSGGN---SSSSTSSGGGGGGGSNSGSSA------------------------- -------------------------------------------------------------------------------- -FNPQGEPSEQPYEHLTTESF----------------------------------------------------------- -----------------------------------SDIALNNEKAMVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MTNPP TSSSSAPSPAASSSS---------------------------------------------------------------SA SQSPPLSCAVPSNDSSPIYSAAPTFPT---------------------------------PNTDIFPEPQSQAFP----- -------GSAGTALQYPPPAYPA---TKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LSLGTPDQKPFQ---GLENRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKALNT------ ------TYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKSVVASPAASSL--SSYP SPVATSYPS----------------PATTSFPSPVPTSYSSPGSSTYPSPAHSGFPSPSVATTFASVP--PAFPTQVS-S FPSAGVSSSFS--TSTGLSDMTATFSPRTIEIC----------------------------------------------- ---- >Canis_familiaris_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGASEGSGGSSSGGSG--GGGGGGGGSGGSSGSA------------------------- -------------------------------------------------------------------------------- -FNPQGEAGEQPYEHLTAESF----------------------------------------------------------- -----------------------------------PDISLNNEKVLVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MTNPP ATSSSAPSPAASSSS---------------------------------------------------------------AA SQSPPLSCAVQSNDSSPIYSAAPTFPT---------------------------------PNSDIFPEPQSQAFP----- -------GSTGAALQYPPPTYPA---AKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LGLGTPDQKPFQ---GLEGRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKTLNT------ ------TYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKGVVASSAATSL--SSYP SQVATSYTSPVTTSYPS--------PATTSYPSPVPTSYSSPGSSTYPSPVHSGFPSPSVATTYSSVP--PAFPAQVS-S FPSSAVTNSFS--ASAGLSDMTTTFSPRTIEIC----------------------------------------------- ---- >Bos_taurus_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGAPEGSSGSSSGSSGGGGGGGGGSSSSNSNSSS------------------------- -------------------------------------------------------------------------------- AFNPQGEASEQPYEHLTAESF----------------------------------------------------------- -----------------------------------PDISLNNEKVLVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MTNPP ATSSSASSPAASSS-----------------------------------------------------------------A SQSPPLSCAVQSNDSSPIYSAAPTFPT---------------------------------PNTDIFPEPQGQAFP----- -------GSAGPALQYPPPAYPG---AKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LGLGTPDQKPFQ---GLESRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKALNS------ ------TYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKS-AASAATSSL--PSYP SPVATSYPSPVTTSYPS--------PATTSYPSPVPTSYSSPGSSTYPSPVHNGFPSPSVATTYSSVP--PAFPTQVS-S FPSSAVTNSFS--ASTGLSDMTTTFSPRTIEIC----------------------------------------------- ---- >Equus_caballus_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGAPEGSGGNSSSSSG--GGGAGGGSSNSSSSSA------------------------- -------------------------------------------------------------------------------- -FNPQGEAGEQPYEHLTSESF----------------------------------------------------------- -----------------------------------PDISLNNEKVLVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MTNPP ATSSSAPSPAASSSS---------------------------------------------------------------SA SQSPPLSCAVQSNDSSPIYSAAPTFPT---------------------------------PNTDIFPEPQNQAFP----- -------GSAGTALQYPPPAYPA---AKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LGLGTPDQKPFQ---GLESRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKALNT------ ------TYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKGVVASSATSSL--SSYP SPVATSYTSPVTTSYPS--------PATTSYPSPVPTSFSSPGSSTYPSPVHSGFPSPSVATTYSSVP--PAFPAQIS-S FPSSAVTNSFS--ASTGLSDMTTTFSPRTIEIC----------------------------------------------- ---- >Loxodonta_africana_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LMSPLQISDPFGSFPHSPTMDN-------------------------------------------- ----------------------------------------------------YPKLEEMMLLS----------------- ----------NGAPQ--FLGAAGAPEGSGGNSSSS----GGGGGGGSGSNSSSSA------------------------- -------------------------------------------------------------------------------- -FNPQGEAGEQPYEHLTAEPF----------------------------------------------------------- -----------------------------------PDISLNNEKVLVETSYPSQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNSGN----TLWPEPLFSLVSGLVS----------MSNPP ATSTSAPSPAASSSS---------------------------------------------------------------SA SQSPPLSCAVQSNDSSPIYSAAPTFPT---------------------------------PNTDIFPEPQSQSFS----- -------GSAGTALQYPPPAYPA---AKGGFQVP---------------------------------MIPDYLFPQQQGD ------------------LGLGTPEQKPFQ---GLESRTQQPSLTPLSTIKA---------------FATQSG------- -----------------------------------------------------------------SQDLKALNN------ ------TYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKSVVASSATSSL--SSYP SPVATSYPSPVTTSYPSPVTTSYPSPATTSYPSPVPTSYSSPGSSTYPSPVHSGFSSPSVATTYSSVP--PAFPAQVS-S FPSSAVANSFS--ASTGLSDMTATFSPRTIEIC----------------------------------------------- ---- >Gallus_gallus_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKAEMQ---------------- --------------LLPSLQISDPFGVFPHSPPAMDGH------------------------------------------ ----------------------------------------------------YPKLEEMMLLS----------------- ----------GGGQQ--FLAPSGAPESAG--------------------------------------------------- -------------------------------------------------------------------------------- -FGAAGEPSEQHFEHLAADTF----------------------------------------------------------- -----------------------------------PEISLNNEKTMPETSYPNQTTRLP--------------------- ---------------------------PITYTGRFSLEPAPNGSN----TLWPEPLFSLVSGLVS----------MANAP PTSTPSSS--SPSSS----------------------------------------------------------------- -QSTPLSCSVQASENSPIYSAAPTFPT---------------------------------SSSDIFPEPQTQPFP----- -------NPSGVPIQYPPPAYPT---AKTNFQVP---------------------------------MIPDYLFPQQQSE ------------------LNLISADQKPFS---ALETRAQQPSLTPLSTIKA---------------FATQTG------- -----------------------------------------------------------------SQELKTLNT------ ------NYQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKVEKAASVSATSSSV--AAYS SSVATSYSS----------------SIATTYPSSVRTVYSSPASSSYPSPAHTTFPSPSIATTYSSGT--ATFQTQVATS FPSPGVTNNFSSQVTSALSDMTSTFSPRTIEIC----------------------------------------------- ---- >Xenopus_tropicalis_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKTDML---------------- --------------VSP-LQISDPFSSFPHSP-TMD-N------------------------------------------ ----------------------------------------------------YPKLEEMMLLN----------------- ----------PGAPQ--FLG-AAVPEGSG--------------------------------------------------- -------------------------------------------------------------------------------- -FNSPVE-GSEQFDHLAADAF----------------------------------------------------------- -----------------------------------SDMSLSGEKAVIESSYANQSARLP--------------------- ---------------------------SLTYTGRFSLEPAPNSSN----TLWPEPLFSLVSGLVG----------MANAS PSSAPSSSPSSSSSS----------------------------------------------------------------- SQSPPLSCSVQSNDSSPIYSAAPTFPN---------------------------------SSPELFPDQSPQPFQ----- -------NASTASIPYPPPAYPV---SKTTFQVP---------------------------------MIPDYLFPQQQGD ------------------VSLVSADQKPFQ---AMESRTQQPSLTPLSTIKA---------------FATQT-------- -----------------------------------------------------------------SQDLKTINS------ ------TYQSQIIKPSRMRKYPN----------RPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--ICGRKFARSDERKRHTKIHLRQKDKKADKATPVS-VASPV--SSYS PSASTSY------------------------PSPVPTSYSSPVSSAYPSPVHSSFPSPTTAVTYPSVT--STFQTHGITS FPSSIVTNSFSSPVSSALSDMSITYSPRTIEIC----------------------------------------------- ---- >Danio_rerio_EGR1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKTEM----------------- --------------LLPALQISDPL-SFPHSP-TDN-------------------------------------------- ----------------------------------------------------YPKLEEMIMLN----------------- ----------SAGTP--FLNATAPEGAVFG-------------------------------------------------- -------------------------------------------------------------------------------- ----SGEPGEQFD-HLAGDTL----------------------------------------------------------- -----------------------------------SEISM--EKPLSDQTYS--TQRLP--------------------- ---------------------------PISYTGRFTLEPATNCSN----SLWAEPLFSLVSGLVG------INPPPASIP SSTSQATHPSSSSTSSIP--------------------------------------------------------SSSSSS TSSASLSCSVHQSEPNPIYSAAPTYSS---------------------------------ASPDIFPE-SGPNFS----- -------TTVGTSLQYSSSTYPSAKTCNPSFSVP---------------------------------MIPDYLFTQQQSE ------------------ISLVPPDQKPIQ---TQAG--QQPALTPLHTIKA---------------FATQTG------- -----------------------------------------------------------------SQDLKSV-------- -------YQSQLIKPSRMRKYPN----------RPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACE--ICGRKFARSDERKRHTKIHMRQKDKKAEKGATAAVQSSVSNISISA SSPVSSYPSP-----------------ITSYPSPV-SSFPSPVNSCYSSPVHTSYPSPSIATTYPSA--TSTFQTQVATS FPTSVASNIYSSPVTTPLPDMQSALSPRTADIC----------------------------------------------- ---- >Takifugu_rubripes_EGR1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKTEM----------------- --------------ILPALQLSEPL-SFPHSP-MDN-------------------------------------------- ----------------------------------------------------YPKLEE---------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------GEQYDHHLAGDTL----------------------------------------------------------- -----------------------------------PDIPFNCEKP--EQTYP--TQRLP--------------------- ---------------------------PISYTGRFTLEPATTCSN----SLWAEPILGLFTGLMGNIAPSSNSSSAASQT ASSSSSTTPSSSVSS-----------------------------------------------------------SSTTSS SQSSSLSSSIHHSEPNPIYSAAPTYSS---------------------------------PNSDIFPD-QGQAFP----- -------TSAG-GVQYPPPAYPNGKTCSTSFPVP---------------------------------MIPDYLFPQQQGE ------------------ISLVPPDQKPFQ---SQT---SQPSLTPLSTIKA---------------FATQTG------- -----------------------------------------------------------------SQDLKSV-------- -------YQSQLIKPSRMRKYPT----------RPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACE--ICGRKFARSDERKRHTKIHLRQKDKKAEKTGVVAVTAAP---VSAA SP-ASSYPSP-----------------ITSYPSPV-SSYPSPATSCYSSPVHTSYPSPSIATTYPSASMSSTFQSQVASS FPSSVASNIYNSPIPTPISDIQTTLSPRTIEIC----------------------------------------------- ---- >Tetraodon_nigroviridis_EGR1_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MAAAKTEM----------------- --------------ILPALQLSEPL-SFPHSP-MDN-------------------------------------------- ----------------------------------------------------YPKLEEVMMLS----------------- ----------SAGTP--FHTASAPEGAGFG-------------------------------------------------- -------------------------------------------------------------------------------- ----SGEPGEQYD-HLAGDTL----------------------------------------------------------- -----------------------------------PDIPFNCEKP--EQTYP--TQRLP--------------------- ---------------------------PISYTGRFTLEPATTCSN----SLWAEPILGLFTGLT---------------- TSSSSSTTPSSTASS-----------------------------------------------------------SSSTSS SQSSSLSSSIHHSEPNPIYSAAPTYSS---------------------------------PNSDIFPD-QGQAFP----- -------TSAG-GVQYPPPAYPNGKTCSTSFPVP---------------------------------MIPDYLFPQQQAE ------------------ISLVPPDQKPFQ---SQT---SQPSLTPLSTIKA---------------FATQTG------- -----------------------------------------------------------------SQDLKSV-------- -------YQSQLIKPSRMRKYPT----------RPSKTPPHERPYACPMETCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACE--ICGRKFARSDERKRHTKIHLRQKDKKAEKTGAVGVTAAP---VSAA S----------------------------------------------------------IATTYPSASMSNTFQSQVASS FPSSVASNIYNSPIPTPISDIQTTLSPRTIEIC----------------------------------------------- ---- >Gasterosteus_aculeatus_EGR1a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------GGGGGGG----------------- --------------GGEWVGGGGGG-ALPESA-CRT-------------------------------------------- ----------------------------------------------------CP-------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------EAHLPADTL----------------------------------------------------------- -----------------------------------PDIPFNCEKSMGDQTYP--TQRLP--------------------- ---------------------------PISYTGRFTLEPATACSN----SLWAEPILGLFTGLM---------------- ASQTTSSSSASIPSS-----------------------------------------------------------TSSSST SSSQSLSSSIHHNEPNPIYSAAPTYSS---------------------------------PNSDIFPD-QGQAFP----- -------SSGG-GVQYPPPAYPNGKTCNTSFPVP---------------------------------MIPDYLFPQQQGE ------------------ISLVPPDQKPFQ---SQS---NQPSLTPLSTIKA---------------FATQTG------- -----------------------------------------------------------------SQDLKSV-------- -------YQSQLIKPSRMRKYPT----------RPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACE--ICGRKFARSDERKRHTKIHLRQKDKKAEKTGAVVVTAAA---ATSA SSPASSYPSP-----------------ITSYPSPV-SSYPSPVTSCYSSPVHTSYPSPSIATTYPSVSMSSTFQSQIASS FPSSVAS------------------------------------------------------------------------- ---- >Ciona_intestinalis_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MLAYVSDNVALHSKIPEADPSWNIWDKNEENIWEFRQVSMQCN---------------- --------------DDYDVTWPEEFSCFDNKESLCSNN------------------------------------------ ---------------------------------------------------CVEQDTDMKIEPVG--------------- ------------VVSPTLPHAVDGSAG----------------------------------------------------- -----------------------------------------------------------------------------VDC EVLLETNITMDHTHNQCGDGK----------------------------------------------------------- --------------------------------NLPSYESAVMELPEYRERHFATKPHDIG-------------------- -------------------EMSTLQYMPAHHQASFSYPYPSYAVVSPVPGKDETSCLPPLLHHSMVQETFPP---IISSP GFHPRSPDQKQERPFKSH--------------------------------------------------------LHATYS SPASLESARSPQPQLETPIPYPTYFPQTSRSPN---------------------------QLNPFYEAKGDTEDHYNYN- ------PQPTVKIEPFSPPQQDYTSSVTSVFPPLRSSP-------------------------AMTQQELEYSEFVAQCN QST---------------PGPSYQADHGIVLNGEVHLRIQQTYLPQSEVFHEN------YNRQQEQEFIPRSDEKYPPTF G-----------------------------------------------------SSHIQLSTPFVQPPPPYNDHNGGIPD HHFQPSVFTPQFTPDARCRSQPTRGKGRSAK--RPSRVLPQDRPYACPMQGCDKKFSRTDELNRHVRIHTGVKPFTC--P ECQRRF-SRSDHLRTHTRTHTG---EKPYNCK--ICSKRFARSDECKRHTRIHNKVKTKKLIMTSPKQRTVTSQVET--- ------------------------------MTTMTSHHPGYPSGSMTSLSVDNAMQQSCFTYQ----------------- -------------------------------------------------------------------------------- ---- >Drosophila_melanogaster_EGR1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -----------------------------------------------------------------------------MLL TMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPP PAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTE QSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPY LYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTA AQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTA TPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTT VVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTT TTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLP NHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQ----------- ASKISYRGIFTTTGN---------------------------------------------------------------AM NAAAAAAAAAAQQQHQQQQQHQQQLPS-PQLGV---------------------------LAGPMSPPSNSLGNSWGLPS PDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPP SYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQ----QVQQ------QQQQQQTLVLPGPT SSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVY------ ----QQSTVPLKLVPVKPRKYPN----------RPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCD--ICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQ------ ------------------------------QQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMX RLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVS VQEK >Homo_sapiens_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MMTAKAV------------------ --------------DKIPVTLSG--FVHQLSDNIYP-------------------------------------------- -------------------------------------------------------VEDLAA------------------- ------------TSVTIFPNAELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINIDMTG------------------------------------------------------------ -------------------------------------EKRSLDLP-YPSSFAPVSAPRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAS-----CYPEGIINIVSAGILQGVT---------SP ASTTASSSVTSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPDLDHLYSPPPPPPP---YSG---------------------------CAGDLYQ-DPSAFLSAAT-- ------TSTSSS-LAYPPPPSYPSPKP--ATDP------------------------------GLFPMIPDYPGFFPSQ- CQR-------------DLHGTAGPDRKPFP-CPLDTLRV-PPPLTPLSTIRN---------------FTLGGPSAGVTG- ---------------------------------------------------------PGASGGSEGPRLPGSSSAAAAAA AAAAYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--YCGRKFARSDERKRHTKIHLRQKERKSSAP--SASVPAPS------ ------------------------------TAS--CSGGVQPGGTLCSS-NSSSLGGGPLAPCSSRTRTP---------- -------------------------------------------------------------------------------- ---- >Mus_musculus_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MMTAKAV------------------ --------------DKIPVTLSG--FMHQLPDSLYP-------------------------------------------- -------------------------------------------------------VEDLAA------------------- ------------SSVTIFPNGELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINIDMTG------------------------------------------------------------ -------------------------------------EKRPLDLP-YPSSFAPISAPRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAS-----CYPEGIINIVSAGILQGVT---------PP ASTTASSSVTSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPELDHLYSPPPPPPP---YSG---------------------------CTGDLYQ-DPSAFLSPPS-- ------TTSTSS-LAYQPPPSYPSPKP--AMDP------------------------------GLIPMIPDYPGFFPSP- CQR-------------DPHGAAGPDRKPFP-CPLDSLRV-PPPLTPLSTIRN---------------FTLGGPGAGVTG- ---------------------------------------------------------PGASGGGEGPRLPGSGS---AAV TATPYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--YCGRKFARSDERKRHTKIHLRQKERKSSAP--SAPPSAQS------ ------------------------------SAS--GPGGSQAGGSLCG---NSAIGG-PLASCTSRTRTP---------- -------------------------------------------------------------------------------- ---- >Canis_familiaris_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------MRVGLPSEASSCRWPARGPR------------------ --------------DRPERRRSG--LAHVLSDNIYP-------------------------------------------- -------------------------------------------------------VEDLAA------------------- ------------TSVTIFPNAELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINIDMTG------------------------------------------------------------ -------------------------------------EKRSLDLP-YPSSFAPVSAPRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAS-----CYPEGIINIVSAGILQGVT---------SP ASTTASSSVTSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPDLDHLYSPPPPPPP---YSG---------------------------CTGDLYQ-DPSAFLSAAT-- ------TSTSSS-LAYPPPPSYPSPKP--ATDP------------------------------GLFPMIPDYPGFFPSQ- CQR-------------DLHGTAGPDRKPFP-CPLDSLRV-PPPLTPLSTIRN---------------FTLGGPSAGATG- ---------------------------------------------------------PGPSGGSEGPRLPGSS----SAA AAAAYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--YCGRKFARSDERKRHTKIHLRQKERKSSAP--SSSVPAAS------ ------------------------------TAS--CPGGSQAGGPLCSS-NGSTIGGGSLAPCSSRTRTP---------- -------------------------------------------------------------------------------- ---- >Bos_taurus_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MMTAKAV------------------ --------------DKIPVTLSG--FVHQLSDNIYP-------------------------------------------- -------------------------------------------------------VEDLAP------------------- ------------TSVTIFPNAELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINIDMTG------------------------------------------------------------ -------------------------------------EKRSLDLP-YPSSFAPGSAPRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAG-----CYPEGIINIVSAGILQGVT---------SP ASTTASSSITSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPDLDHLYTPPP-PPP---YAG---------------------------CGGDLYQ-DPSAFLSAAT-- ------TSTSSS-LAYPPPPSYPSPKP--ATDP------------------------------SLFPMIPDYPGFFPSQ- CQR-------------DLHGTAGPDRKPFP-CPLDSLRV-PPPLTPLSTIRN---------------FTLGGPSAGATG- ---------------------------------------------------------PGAGGGSEGPRLPGTGS---AAA AAAAYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--YCGRKFARSDERKRHTKIHLRQKERKSSAP--SSAVPAAS------ ------------------------------SAS--CSGGAQAGGTLCSS-NSSTIGGGSLGPCSSRTRTP---------- -------------------------------------------------------------------------------- ---- >Equus_caballus_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------MMTAKAV------------------ --------------DKIPVTLSG--FVHQLSDNIYP-------------------------------------------- -------------------------------------------------------VEDLAA------------------- ------------TSVTIFPNAELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINVDMTG------------------------------------------------------------ -------------------------------------EKRSLDLP-YPSSFAPVSATRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAS-----CYPEGIINIVSAGILQGVT---------SP ASTTASSSVTSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPDLDHLYSPPPPPPP---YSG---------------------------CVGDLYQ-DPSAFLSPAT-- ------TSTSSS-LAYPPPPSYPSPKP--ATDP------------------------------GLFPMIPDYPGFFPSQ- CQR-------------DLHGTAGPDRKPFP-CPLDSLRV-PPPLTPLSTIRN---------------FTLGGPSAGATG- ---------------------------------------------------------PGASGGSEGPRLPGSS---SAAA AAAAYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--FCGRKFARSDERKRHTKIHLRQKERKGSAP--SSSVPAAS------ ------------------------------TAS--CTGGTQPGGPLCSS-NSGTLGGGSLAPCSSRTRTP---------- -------------------------------------------------------------------------------- ---- >Loxodonta_africana_EGR2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------------------------------------------PAKAV------------------ --------------DKIPVTLSG--FVHQLSDNIYP-------------------------------------------- -------------------------------------------------------VEDLAA------------------- ------------TSVTIFPNAELGG------------------------------------------------------- -------------------------------------------------------------------------------- PFDQMNGVAGDGMINIDMTG------------------------------------------------------------ -------------------------------------EKRSLDLP-YPSSFAPVSAPRN--------------------- --------------------------QTFTYMGKFSIDPQYPGAS-----CYPEGIINIVSAGILQGVT---------SP ASTTASSSVTSASPNP------------------------------------------------------------LATG PLGVCTMSQT-QPDLDHLYSPPPPPPP---YSG---------------------------CAGDLYQ-DASAFLSAAT-- ------TSASSSSLAYPPPPSYPSPKP--ATDP------------------------------GLFPMIPDYPG-FPSQ- CQR-------------DLHGAAGPDRKPFP-CPLDSLRV-PPPLTPLSTIRN---------------FTLGGPSAGATG- ---------------------------------------------------------PGVSGGSEGPRLPGSSS--AAAA AAASYNPHHLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--YCGRKFARSDERKRHTKIHLRQKERKSSAP--SSSVQAVS------ ------------------------------TAT--CVGGTQAGGALCSS-NSGTIGGGALAPCSSRTRTP---------- -------------------------------------------------------------------------------- ---- >Danio_rerio_EGR2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------------------------------------------------MTATASTG------------------ --------------DKMSASLTD--FMRCLPSHVYG-------------------------------------------- -------------------------------------------------------LDEIP-------------------- -----------PCAPTGFPHVDAGV------------------------------------------------------- -------------------------------------------------------------------------------- CSDHYSEASAGGLSSDS---F----------------------------------------------------------- -----------------------------------GVEKRDLDLP-DPGKFSP--HSAP--------------------- ----------------------------VAYTGKISID---AQGS-----WSQEGIINFISAGVQDR------------- -----STSPGSFSTGS------------------------------------------------------------PAGP PSDCSKIVQN-LPNMEHMYTGP-------PPYT---------------------------CSAEGYQ-DPSV--YLST-- ------TTCPIT--YAPPS--YSAPKS--TIDG------------------------------ALFSIIPDYGGFYQNSS CQRDN--------------MAVFQDIKPFS-CSLESIRV-PPPLTPLNTIRN---------------FTLACPVDGSRP- ---------------------------------------------------------PLDG------------------- --TNP--QNVPLRPILRPRKYPN----------RPCKTPVHERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCD--FCGRKFARSDERRRHTKIHQRHKDRKLSVG--PHSSSAGG------ ------------------------------N------------------------------------------------- -------------------------------------------------------------------------------- ---- >Danio_rerio_EGR2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTAKTL-E---------------- --------------KA-PVSLGG--FVHPLADSIYS-------------------------------------------- -------------------------------------------------------VDELATTL----------------- ----------P-ASVTIYN--DLGG------------------------------------------------------- -------------------------------------------------------------------------------- HYEQIN--AGDGLINGDMST------------------------------------------------------------ -------------------------------------EKRALDLA-YSSSFAQPAGPRN--------------------- --------------------------QTFTYMGKFSIDSQYPGN------WNPEGVINIVSAGILGMTQP---------- -SSASSSPASSVSPSH------------------------------------------------------------FSS- -TLSCTMAQN-QADMEHIY---SPPPPY--S-----------------------------GCGEVYQ-DPSAFLS----- --------TSTCPIS-YPPPSYSSPKP--NADS------------------------------GLFPIIPDYAGFFQPP- CQR-------------DMQS--MPDRKPFS-CPLDSFKL-PPPLTPLNTIRN---------------FTLGGPVPDG--- ------------------------------------------------------------------PRLPT--------- ---AYTPQNLPLRPILRPRKYPN----------RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--FCGRKFARSDERKRHTKIHLRQKERKSSSS--STGVSSSE------ ------------------------------RGVATSICSSSSNQ------------------------------------ -------------------------------------------------------------------------------- ---- >Takifugu_rubripes_EGR2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTAKAL-E---------------- --------------KV-PVNLGG--FVHPPVDSVYS-------------------------------------------- -------------------------------------------------------VDDIP-------------------- -------------AVAIFPSSDLGA------------------------------------------------------- -------------------------------------------------------------------------------- HYDQMN-VMADGLMGGDMST------------------------------------------------------------ -------------------------------------EKRSLDLSSYSSSFTQPVPHRS--------------------- --------------------------QTFTYMGKFSIDSQYPGN------WNPEGVLNIVSG-IFNVAQPPPPP--PP-- SSSASSSPVSSGSPHH------------------------------------------------------------FSS- GNLNCTMATQSQAEMEHHH-LYSPPPPY--SSS---------------------------GCGESYQ-DPSAFLS----- --------TSTCPIGSYPQPSYSSPKPPGNPDA-------------------------------LFPILPDYSGFFQPA- CQR-------------DMHTSTIQDRKPFGPCHLDTFRV-PPPLTPLNTIRN---------------YTLGGAGGGSSE- ---------------------------------------------------------GGA------PRLPS--------- ---AYSPQNLPLRPILRPRKYPN----------RPSKTPIHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--FCGRKFARSDERKRHTKIHLRQKERKSSTV--SSASSSNS------ ------------------------------GGTTTTPRISLCL------------------------------------- -------------------------------------------------------------------------------- ---- >Tetraodon_nigroviridis_EGR2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------SLASYPSPSYSFPKPPGSSDA-------------------------------LFPIIPDYPGFFQPA- CQR-------------DMNASSVQDRKPFGPCPLDTFRV-PPPLTPLNTIRN---------------YTLGGPGGGSTE- ---------------------------------------------------------GGA------PRLPS--------- ---AYSPQNLPLRPILRPRKYPN----------RPSKTPIHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQS--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--FCGRKFARRPSRKRHTKIHLRQKERKSAAV--SLSSASSA------ ------------------------------SSS----------------------------------------------- -------------------------------------------------------------------------------- ---- >Gasterosteus_aculeatus_EGR2_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTAKLA------------------ --------------NEVFASLSG--FVESIPKDVYS-------------------------------------------- -------------------------------------------------------AEG---------------------- --------------SVVFKEEAVGE------------------------------------------------------- -------------------------------------------------------------------------------- EEDD----SGGFLFEGK--------------------------------------------------------------- -------------------------------------SVPELPYHGDFAQYVATLRTQP--------------------- ----------------------------VAFTGKISVDSRGAGGP-----WTPRDIINVISADIAVP------------- ---VSGSCSGSPEICA------------------------------------------------------------TAEA G--DCTMAHG-HPDISHMYAP--------PSYS---------------------------CSGDMYQ-DQSAGGYLSA-- ------STCSVS--YHPPPTYNPPPKP--TVDGG-----------------------------ALLSIMPEYGGFYQQS- CQRDI--------------QAAFPERKSLA-YSLDSLRV-PPPLTPLNTIRN---------------FTLGAPSAAAEG- ---------------------------------------------------------PMAA------------------- --AFPSHQSLPLRPILRPRKYPN----------RPSKTPVHQRPYPCPAESCDRRFSRSDELSRHLRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFSCD--QCGRKFARSDERRRHMKIHLRQKEKKASA----------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---- >Gasterosteus_aculeatus_EGR2_b -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------TMTAKTL-E---------------- --------------KV-PLNLGG--FVHP--ESVYS-------------------------------------------- -------------------------------------------------------VDDIGSSL----------------- ----------A-TSVAIFPNSDLGA------------------------------------------------------- -------------------------------------------------------------------------------- HYDQMN-VSADGLMNADMS------------------------------------------------------------- -------------------------------------EKRSLDFSPYSSGFSQNASHRN--------------------- --------------------------QTFTYMGKFSIDSQYPGN------WNPEGVINIVSG-IFNVAQPPPPP--PP-- SSSASSSPASSGSPNH------------------------------------------------------------FHSS GNLSCTMAAQNQAEMDHHHHLYSPPPPY--SSS---------------------------GCGEMYQ-DPSAFLS----- --------TSTCSIASYPPPSYSSPKQHGSAEAP-----------------------------GLFPIIPDYSGFFQPA- CQR-------------DMHTAGIQDRKPFGPCPLDPFRV-PPPLTPLNTIRN---------------FTLG-PGGSGSE- ---------------------------------------------------------GGA------PRLPS--------- ---AYSPQNLPLRPILRPRKYPN----------RPSKTPIHERPYPCPADGCDRRFSRSDELTRHIRIHTGHKPFQC--R ICMRNF-SRSDHLTTHIRTHTG---EKPFACD--FCGRKFARSDERKRHTKIHLRQKERKSSTV--SSSSSSSS------ ------------------------------S-SSGVERLSAAISATSG-------------------------------- -------------------------------------------------------------------------------- ---- >Homo_sapiens_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPVTMSS--LLNQLPDNLYP-------------------------------------------- --------------------------------------------------------EEIPS------------------- -------------ALNLFSGSSDSVV------------------------------------------------------ -------------------------------------------------------------------------------- HYNQMAT---ENVMDIGLTN------------------------------------------------------------ -------------------------------------EKPNPELS-YSGSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCGDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSIPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKAEKG----GAPSAS------ ------------------------------SAPPVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Mus_musculus_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPVTMSS--LLNQLPDNLYP-------------------------------------------- --------------------------------------------------------EEIPS------------------- -------------ALNLFSGSSDSVA------------------------------------------------------ -------------------------------------------------------------------------------- HYNQMAT---ENVMDIGLTN------------------------------------------------------------ -------------------------------------EKPNPELS-YSSSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCGDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSIPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKSEKG----GAPSAS------ ------------------------------SAPTVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Canis_familiaris_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPVTMSS--LLNQLPDNLYP-------------------------------------------- --------------------------------------------------------EEIPS------------------- -------------ALNLFSGSSDSVA------------------------------------------------------ -------------------------------------------------------------------------------- HYNQMAT---ENVMDIGLTN------------------------------------------------------------ -------------------------------------EKPNPELS-YSGSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCSDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSIPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKAEKG----GAPSAS------ ------------------------------SAPPVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Bos_taurus_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPVTMSS--LLNQLPDNLYP-------------------------------------------- --------------------------------------------------------EEIPS------------------- -------------ALNLFSGSSDSVA------------------------------------------------------ -------------------------------------------------------------------------------- HYNQMAT---ENVMDIGLTN------------------------------------------------------------ -------------------------------------EKPNPELS-YSGSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCSDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSMPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKAEKG----GAPSAS------ ------------------------------SAAPVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Equus_caballus_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPVTMSS--LLNQLPDNLYP-------------------------------------------- --------------------------------------------------------EEIPS------------------- -------------ALNLFSGSSESVA------------------------------------------------------ -------------------------------------------------------------------------------- HYNQMAT---ENVMDIGLTN------------------------------------------------------------ -------------------------------------EKPNPELS-YSGSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCSDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSIPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKAEKG----GAPSAS------ ------------------------------SAPPVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Loxodonta_africana_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------MEPCAA------------------------------------------------------ -------------------------------------------------------------------------------- WSPRGGR---ENVMDIGLPN------------------------------------------------------------ -------------------------------------EKPNPELS-YSGSFQPAPGNKT--------------------- ----------------------------VTYLGKFAFDSP-------SNWCQDN-IISLMSAGILGVPP----------- ASGALS-TQTST-------------------------------------------------------------------- ----ASMVQPPQGDVEAMYP-ALPPYS---------------------------------NCSDLYS-EPVSFHD----- -------PQGNPGLAYSPQDYQS-AKP--ALDS------------------------------NLFPMIPDYNLYHHPN- ------------------DMGSIPEHKPFQ--GMDPIRVNPPPITPLETIKA---------------FKDK--------- ---------------------------------------------------------------QIHPGFGSLP------- ------QPPLTLKP-IRPRKYPN----------RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFACE--FCGRKFARSDERKRHAKIHLKQKEKKAEKG----GAPSAS------ ------------------------------SAPPVSLA---PVVTTCA-------------------------------- -------------------------------------------------------------------------------- ---- >Danio_rerio_EGR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------DKIPITMSS--LINTIPDSLYPE------------------------------------------- --------------------------------------------------------EDIPT------------------- -------------SMNIFAN-PDSIS------------------------------------------------------ -------------------------------------------------------------------------------- HYSQMNT---DNIMDLGMGG------------------------------------------------------------ -------------------------------------EKGSGEIQYGSGSFQSGRSGQT--------------------- ----------------------------VTYLGKFAFDTPPSGSIGGSGWCPDNNIISLVSAGILGVSP----------- SPGNIT-TQTSS--S----------------------------------------------------------------- ----SGSMGGQSSDMEQVYAPPLPAYS---------------------------------TCGEIYP-EQVTFHHS---- -------PATSSSLPYPSSDYHTTSKP--GMDG------------------------------SLFSMIPDYNLFHHQG- ------------------DVGVM-EHKPFQ--TMDPIRVNPPPITPLETIRA---------------FKDKQQIH----- ---------------------------------------------------------PGFLGGQQHVSQHHQP------- ------SQTLALKP-IRPRKYPN----------RPSKTPVHERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCE--FCGRKFARSDERKRHAKVHLKQKDKKPTDKGSSAGAGGNH------ ------------------------------TSPPSSCGSAGPSSTNIMTVTTCA-------------------------- -------------------------------------------------------------------------------- ---- >Takifugu_rubripes_EGR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPLTMSS--LINTIPDSLYPE------------------------------------------- --------------------------------------------------------EDIPT------------------- -------------SMNIFTN-TESIS------------------------------------------------------ -------------------------------------------------------------------------------- HYSQMNSGAADNIMDLGMGS------------------------------------------------------------ -------------------------------------EKAAAEIQYGS-SFQSNRSAQT--------------------- ----------------------------VTYLGKFAFDTPPSGGIGGSGWCSDNNIISLVSAGILGVSP----------- SPGTVT-TQTSSAAA----------------------------------------------------------------- ----AASMGGQTSDMEQVYGPPLPAYS---------------------------------TCSDLYQ-DQVSFHHS---- -------PATSTTLAYPGNDYHSTPKG--SMDG------------------------------SLFSMIPDYNLFHHQG- ------------------EVGVM-EHKPFQ--TMDPIRVNPPPITPLETIRA---------------FK----------- ----------------------------------------------------------GFISGQQHPPQHHPP------- ------PQTLTLKP-IRPRKYPN----------RPSKTPVHERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCE--FCGRKFARSDERKRHAKVHLKQKDKK-------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---- >Tetraodon_nigroviridis_EGR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPLTMSS--LINTIPDNLYPE------------------------------------------- --------------------------------------------------------EDIPT------------------- -------------SMNIFTN-TESIS------------------------------------------------------ -------------------------------------------------------------------------------- HYSQMNT---DNIMDLGMGS------------------------------------------------------------ -------------------------------------EKATAEIQYGS-SFQSNRSAQT--------------------- ----------------------------VTYLGKFAFDTPPSGGIGGSGWCSDNNIISLVSAGILGVSP----------- SPGTVT-TQTSS--S----------------------------------------------------------------- ----ATSMGGQTSDMEQVYGPPLPAYS---------------------------------TCSDLYQ-DQVSFHHS---- -------PATSTTLAYPGNDYHSTPKG--SMDG------------------------------SLFSMIPDYNLFHHQG- ------------------EVGVM-EHKPFQ--TMDPIRVNPPPITPLETIRA---------------FK----------- ----------------------------------------------------------GFISGQQHPPQHHPP------- ------PQTLTLKP-IRPRKYPN----------RPSKTPVHERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCE--FCGRKFARSDERKRHAKVHLKQKDKKPADK--SSGATGSH------ ------------------------------SSPPSSCG--GPTVGT---------------------------------- -------------------------------------------------------------------------------- ---- >Gasterosteus_aculeatus_EGR3_a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- --------------------------------------------------------MTGKLA------------------ --------------EKLPLTMSS--LINTIPDSLYPE------------------------------------------- --------------------------------------------------------EDIPT------------------- -------------SMNIFTS-TESIN------------------------------------------------------ -------------------------------------------------------------------------------- HYSQMNT---DNIMDLGMGS------------------------------------------------------------ -------------------------------------EKASAEIQYGS-SFQSNRSGQT--------------------- ----------------------------VTYLGKFAFDTPPSGGIGGSGWCSDNNIISLVSAGILGVSP----------- SPGTVT-TQTSS--S----------------------------------------------------------------- ----AASMGGQTSDMEQVYGPPLPAYS---------------------------------TCSDLYQ-DQVSFHHS---- -------PATSTGLAYPGNDYHSTSKA--SMDG------------------------------SLFSMIPDYNLFHHQG- ------------------EVGVM-EHKPFQ--TMDPIRVNPPPITPLETIRA---------------FKDKQQIH----- ---------------------------------------------------------PGFIGGQQHPPQHHPQ------- ------PQTLTLKP-IRPRKYPN----------RPSKTPVHERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQC--R ICMRSF-SRSDHLTTHIRTHTG---EKPFSCE--FCGRKFARSDERKRHAKVHLKQKDKKPADK--SSGAAGSH------ ------------------------------SSPPGSCG--GPTVGTS--------------------------------- -------------------------------------------------------------------------------- ---- >Ciona_savignyi_EGR3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ------------MAAAVALNYPSPNFSNEFPAETFYNP------------------------------------------ -------------------------------------------------------------------------------- ------------QSLEQVASVSDISSFSPVSSPDFLS------------------------------------------- -----------------------------------------------------------------------FDHNAISDS SIDSLECAMNEYYIDQQLDNS----------------------------------------------------------- ---------------------------SMKNGDVIMPPPMTSRLPYSSDLNTFRRESASDI------------------- --------------------------HDILNCGLKNNCQVYQGNNNCNNIYQQTNNYNNIDTNNGSCVNVNFNVSPNMLH IPPVSSFIKNSEAILHQSASPTIKTSPHPYPQIHHEEFTRTRIPSESESLCYDQRRHASLPSITITNLDESESMLHNYQR PRSTSLTTERCSNPPTSPNPASPPVQMTSQQPCSP------------------------LGIHTAKQYVKTEATDCNAQM ANWDSSIGMFTEPAVSPYSRRCSSEIGAINAPTD-----------------------------GYMPMNVMLPAKHEKMY TDDQFVSSNPPYSCQTTGITSTYPCNQQPMFPPSQINFPPILETSSASTVLQQHCHNAHPTMGHGAQMQSENRRHSSEI- ----------------------------------------------------------------TLHRRSHPYLGMSVPP PYPLAVNGTIPYRPRYSRRNNPDL---------------EKKRVHKCTHTGCTKAYTKSSHLKAHQRTHTGEKPYTCNWQ GCDWRF-ARSDELTRHMRKHTG---AKPFKCL--VCGRCFSRSDHLSLHMKRHQA------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---- >Homo_sapiens_EGR4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------------------MAVARGVGSPEPAPPQLYKWGGCGLGEPGSALERRGAAARGRCGRARAPRLPDSFPRGE CPKPGARAPRSVRCGEP